HR c.553_554delinsTG ;(p.P185C)

Variant ID: 8-21986130-GG-CA

NM_005144.4(HR):c.553_554delinsTG;(p.P185C)

This variant was identified in 4 publications

View GRCh38 version.




Publications:


Heat Shock Protein 90 as a Prognostic Marker and Therapeutic Target for Adrenocortical Carcinoma.

Frontiers In Endocrinology
Siebert, Claudia C; Ciato, Denis D; Murakami, Masanori M; Frei-Stuber, Ludwig L; Perez-Rivas, Luis Gustavo LG; Monteserin-Garcia, José Luis JL; Nölting, Svenja S; Maurer, Julian J; Feuchtinger, Annette A; Walch, Axel K AK; Haak, Harm R HR; Bertherat, Jérôme J; Mannelli, Massimo M; Fassnacht, Martin M; Korpershoek, Esther E; Reincke, Martin M; Stalla, Günter K GK; Hantel, Constanze C; Beuschlein, Felix F
Publication Date: 2019

Variant appearance in text: HR: P185c
PubMed Link: 31379752
Variant Present in the following documents:
  • fendo-10-00487.pdf
View BVdb publication page



HECTD3 Mediates an HSP90-Dependent Degradation Pathway for Protein Kinase Clients.

Cell Reports
Li, Zhaobo Z; Zhou, Lihong L; Prodromou, Chrisostomos C; Savic, Velibor V; Pearl, Laurence H LH
Publication Date: 2017-06-20

Variant appearance in text: HR: p185c
PubMed Link: 28636940
Variant Present in the following documents:
  • mmc2.pdf
  • main.pdf
View BVdb publication page



Y-632 inhibits heat shock protein 90 (Hsp90) function by disrupting the interaction between Hsp90 and Hsp70/Hsp90 organizing protein, and exerts antitumor activity in vitro and in vivo.

Cancer Science
Wang, Wenqian W; Liu, Yang Y; Zhao, Zhixin Z; Xie, Chengying C; Xu, Yongping Y; Hu, Youhong Y; Quan, Haitian H; Lou, Liguang L
Publication Date: 2016-06

Variant appearance in text: HR: p185c
PubMed Link: 27002306
Variant Present in the following documents:
  • CAS-107-782.pdf
View BVdb publication page



Ganetespib: research and clinical development.

Oncotargets And Therapy
Jhaveri, Komal K; Modi, Shanu S
Publication Date: 2015

Variant appearance in text: HR: p185c
PubMed Link: 26244021
Variant Present in the following documents:
  • ott-8-1849.pdf
View BVdb publication page