HR c.208A>G ;(p.K70E)

Variant ID: 8-21986476-T-C

NM_005144.4(HR):c.208A>G;(p.K70E)

This variant was identified in 11 publications

View GRCh38 version.




Publications:


Virological Failure and Acquired Genotypic Resistance Associated With Contemporary Antiretroviral Treatment Regimens.

Open Forum Infectious Diseases
Rhee, Soo-Yon SY; Clutter, Dana D; Hare, C Bradley CB; Tchakoute, Christophe T CT; Sainani, Kristin K; Fessel, W Jeffrey WJ; Hurley, Leo L; Slome, Sally S; Pinsky, Benjamin A BA; Silverberg, Michael J MJ; Shafer, Robert W RW
Publication Date: 2020-09

Variant appearance in text: HR: K70E
PubMed Link: 32904894
Variant Present in the following documents:
  • Main text
  • ofaa316.pdf
View BVdb publication page



Presentation and outcome of suspected sepsis in a high-HIV burden, high antiretroviral coverage setting.

International Journal Of Infectious Diseases : Ijid : Official Publication Of The International Society For Infectious Diseases
Chaka, Wendy W; Berger, Christopher C; Huo, Stella S; Robertson, Valerie V; Tachiona, Chipo C; Magwenzi, Marcelyn M; Magombei, Trish T; Mpamhanga, Chengetai C; Katzenstein, David D; Metcalfe, John J
Publication Date: 2020-07

Variant appearance in text: HR: K70E
PubMed Link: 32289564
Variant Present in the following documents:
  • Main text
  • nihms-1612039.pdf
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Increasing Prevalence of HIV Pretreatment Drug Resistance in Women But Not Men in Rural Uganda During 2005-2013.

Aids Patient Care And Stds
McCluskey, Suzanne M SM; Lee, Guinevere Q GQ; Kamelian, Kimia K; Kembabazi, Annet A; Musinguzi, Nicholas N; Bwana, Mwebesa B MB; Muzoora, Conrad C; Haberer, Jessica E JE; Hunt, Peter W PW; Martin, Jeffrey N JN; Boum, Yap Y; Bangsberg, David R DR; Harrigan, P Richard PR; Siedner, Mark J MJ
Publication Date: 2018-07

Variant appearance in text: HR: K70E
PubMed Link: 29985647
Variant Present in the following documents:
  • Main text
View BVdb publication page



No Evidence That HIV-1 Subtype C Infection Compromises the Efficacy of Tenofovir-Containing Regimens: Cohort Study in the United Kingdom.

The Journal Of Infectious Diseases
White, Ellen E; Smit, Erasmus E; Churchill, Duncan D; Collins, Simon S; Booth, Clare C; Tostevin, Anna A; Sabin, Caroline C; Pillay, Deenan D; Dunn, David T DT; ,
Publication Date: 2016-11-01

Variant appearance in text: HR: K70E
PubMed Link: 27732929
Variant Present in the following documents:
  • Main text
  • jiw213.pdf
View BVdb publication page



High prevalence of the K65R mutation in HIV-1 subtype C infected patients failing tenofovir-based first-line regimens in South Africa.

Plos One
Skhosana, Lindiwe L; Steegen, Kim K; Bronze, Michelle M; Lukhwareni, Azwidowi A; Letsoalo, Esrom E; Papathanasopoulos, Maria A MA; Carmona, Sergio C SC; Stevens, Wendy S WS
Publication Date: 2015

Variant appearance in text: HR: K70E
PubMed Link: 25659108
Variant Present in the following documents:
  • Main text
  • pone.0118145.pdf
View BVdb publication page



Single-agent tenofovir versus combination emtricitabine plus tenofovir for pre-exposure prophylaxis for HIV-1 acquisition: an update of data from a randomised, double-blind, phase 3 trial.

The Lancet. Infectious Diseases
Baeten, Jared M JM; Donnell, Deborah D; Mugo, Nelly R NR; Ndase, Patrick P; Thomas, Katherine K KK; Campbell, James D JD; Wangisi, Jonathan J; Tappero, Jordan W JW; Bukusi, Elizabeth A EA; Cohen, Craig R CR; Katabira, Elly E; Ronald, Allan A; Tumwesigye, Elioda E; Were, Edwin E; Fife, Kenneth H KH; Kiarie, James J; Farquhar, Carey C; John-Stewart, Grace G; Kidoguchi, Lara L; Coombs, Robert W RW; Hendrix, Craig C; Marzinke, Mark A MA; Frenkel, Lisa L; Haberer, Jessica E JE; Bangsberg, David D; Celum, Connie C; ,
Publication Date: 2014-11

Variant appearance in text: HR: K70E
PubMed Link: 25300863
Variant Present in the following documents:
  • Main text
View BVdb publication page



A comprehensive mutational analysis of the Arabidopsis resistance protein RPW8.2 reveals key amino acids for defense activation and protein targeting.

The Plant Cell
Wang, Wenming W; Zhang, Yi Y; Wen, Yingqiang Y; Berkey, Robert R; Ma, Xianfeng X; Pan, Zhiyong Z; Bendigeri, Dipti D; King, Harlan H; Zhang, Qiong Q; Xiao, Shunyuan S
Publication Date: 2013-10

Variant appearance in text: HR: K70E
PubMed Link: 24151293
Variant Present in the following documents:
  • Main text
View BVdb publication page



Incidence and associated factors of HIV drug resistance in Chinese HIV-infected patients receiving antiretroviral treatment.

Plos One
Xing, Hui H; Wang, Xia X; Liao, Lingjie L; Ma, Yanling Y; Su, Bin B; Fu, Jihua J; He, Jianmei J; Chen, Lin L; Pan, Xiaohong X; Dong, Yonghui Y; Liu, Wei W; Hsi, Jenny H JH; Yang, Liting L; Ruan, Yuhua Y; Shao, Yiming Y
Publication Date: 2013

Variant appearance in text: HR: K70E
PubMed Link: 23638072
Variant Present in the following documents:
  • Main text
  • pone.0062408.pdf
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Abacavir/lamivudine versus tenofovir DF/emtricitabine as part of combination regimens for initial treatment of HIV: final results.

The Journal Of Infectious Diseases
Sax, Paul E PE; Tierney, Camlin C; Collier, Ann C AC; Daar, Eric S ES; Mollan, Katie K; Budhathoki, Chakra C; Godfrey, Catherine C; Jahed, Nasreen C NC; Myers, Laurie L; Katzenstein, David D; Farajallah, Awny A; Rooney, James F JF; Ha, Belinda B; Woodward, William C WC; Feinberg, Judith J; Tashima, Karen K; Murphy, Robert L RL; Fischl, Margaret A MA; ,
Publication Date: 2011-10-15

Variant appearance in text: HR: K70E
PubMed Link: 21917892
Variant Present in the following documents:
  • Main text
View BVdb publication page



Atazanavir plus ritonavir or efavirenz as part of a 3-drug regimen for initial treatment of HIV-1.

Annals Of Internal Medicine
Daar, Eric S ES; Tierney, Camlin C; Fischl, Margaret A MA; Sax, Paul E PE; Mollan, Katie K; Budhathoki, Chakra C; Godfrey, Catherine C; Jahed, Nasreen C NC; Myers, Laurie L; Katzenstein, David D; Farajallah, Awny A; Rooney, James F JF; Pappa, Keith A KA; Woodward, William C WC; Patterson, Kristine K; Bolivar, Hector H; Benson, Constance A CA; Collier, Ann C AC; ,
Publication Date: 2011-04-05

Variant appearance in text: HR: K70E
PubMed Link: 21320923
Variant Present in the following documents:
  • Main text
View BVdb publication page



Adult combination antiretroviral therapy in sub-Saharan Africa: lessons from Botswana and future challenges.

Hiv Therapy
Wester, C William CW; Bussmann, Hermann H; Koethe, John J; Moffat, Claire C; Vermund, Sten S; Essex, Max M; Marlink, Richard G RG
Publication Date: 2009-09-01

Variant appearance in text: HR: K70E
PubMed Link: 20161344
Variant Present in the following documents:
  • Main text
View BVdb publication page