TLR4 c.52C>T ;(p.L18F)

Variant ID: 9-120466802-C-T

NM_138554.4(TLR4):c.52C>T;(p.L18F)

This variant was identified in 10 publications

View GRCh38 version.




Publications:


A novel mutation-proof, next-generation vaccine to fight against upcoming SARS-CoV-2 variants and subvariants, designed through AI enabled approaches and tools, along with the machine learning based immune simulation: A vaccine breakthrough.

International Journal Of Biological Macromolecules
Bhattacharya, Manojit M; Alshammari, Abdulrahman A; Alharbi, Metab M; Dhama, Kuldeep K; Lee, Sang-Soo SS; Chakraborty, Chiranjib C
Publication Date: 2023-05-17

Variant appearance in text: TLR4: L18F
PubMed Link: 37207746
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Peptide candidates for the development of therapeutics and vaccines against β-coronavirus infection.

Bioengineered
Chourasia, Rounak R; Padhi, Srichandan S; Phukon, Loreni Chiring LC; Abedin, Md Minhajul MM; Sirohi, Ranjana R; Singh, Sudhir P SP; Rai, Amit Kumar AK
Publication Date: 2022-04

Variant appearance in text: TLR4: L18F
PubMed Link: 35387556
Variant Present in the following documents:
  • Main text
  • KBIE_13_2060453.pdf
View BVdb publication page



A SARS-CoV-2 Wuhan spike virosome vaccine induces superior neutralization breadth compared to one using the Beta spike.

Scientific Reports
van der Velden, Yme U YU; Grobben, Marloes M; Caniels, Tom G TG; Burger, Judith A JA; Poniman, Meliawati M; Oomen, Melissa M; Rijnstra, Esther Siteur-van ES; Tejjani, Khadija K; Guerra, Denise D; Kempers, Ronald R; Stegmann, Toon T; van Gils, Marit J MJ; Sanders, Rogier W RW
Publication Date: 2022-03-10

Variant appearance in text: TLR4: L18F
PubMed Link: 35273217
Variant Present in the following documents:
  • Main text
  • 41598_2022_Article_7590.pdf
View BVdb publication page



A Next-Generation Vaccine Candidate Using Alternative Epitopes to Protect against Wuhan and All Significant Mutant Variants of SARS-CoV-2: An Immunoinformatics Approach.

Aging And Disease
Bhattacharya, Manojit M; Sharma, Ashish Ranjan AR; Ghosh, Pratik P; Lee, Sang-Soo SS; Chakraborty, Chiranjib C
Publication Date: 2021-12

Variant appearance in text: TLR4: L18F
PubMed Link: 34881093
Variant Present in the following documents:
  • Main text
View BVdb publication page



Phosphate-mediated coanchoring of RBD immunogens and molecular adjuvants to alum potentiates humoral immunity against SARS-CoV-2.

Science Advances
Rodrigues, Kristen A KA; Rodriguez-Aponte, Sergio A SA; Dalvie, Neil C NC; Lee, Jeong Hyun JH; Abraham, Wuhbet W; Carnathan, Diane G DG; Jimenez, Luis E LE; Ngo, Julia T JT; Chang, Jason Y H JYH; Zhang, Zeli Z; Yu, Jingyou J; Chang, Aiquan A; Nakao, Catherine C; Goodwin, Benjamin B; Naranjo, Christopher A CA; Zhang, Libin L; Silva, Murillo M; Barouch, Dan H DH; Silvestri, Guido G; Crotty, Shane S; Love, J Christopher JC; Irvine, Darrell J DJ
Publication Date: 2021-12-10

Variant appearance in text: TLR4: L18F
PubMed Link: 34878851
Variant Present in the following documents:
  • Main text
  • sciadv.abj6538.pdf
View BVdb publication page



Phosphate-mediated coanchoring of RBD immunogens and molecular adjuvants to alum potentiates humoral immunity against SARS-CoV-2.

Science Advances
Rodrigues, Kristen A KA; Rodriguez-Aponte, Sergio A SA; Dalvie, Neil C NC; Lee, Jeong Hyun JH; Abraham, Wuhbet W; Carnathan, Diane G DG; Jimenez, Luis E LE; Ngo, Julia T JT; Chang, Jason Y H JYH; Zhang, Zeli Z; Yu, Jingyou J; Chang, Aiquan A; Nakao, Catherine C; Goodwin, Benjamin B; Naranjo, Christopher A CA; Zhang, Libin L; Silva, Murillo M; Barouch, Dan H DH; Silvestri, Guido G; Crotty, Shane S; Love, J Christopher JC; Irvine, Darrell J DJ
Publication Date: 2021-12-10

Variant appearance in text: TLR4: L18F
PubMed Link: 34878851
Variant Present in the following documents:
  • Main text
  • sciadv.abj6538.pdf
View BVdb publication page



Application of omics technology to combat the COVID-19 pandemic.

Medcomm
Yang, Jingjing J; Yan, Yunzheng Y; Zhong, Wu W
Publication Date: 2021-09

Variant appearance in text: TLR4: L18F
PubMed Link: 34766152
Variant Present in the following documents:
  • Main text
View BVdb publication page



Mechanism of a COVID-19 nanoparticle vaccine candidate that elicits a broadly neutralizing antibody response to SARS-CoV-2 variants.

Science Advances
Zhang, Yi-Nan YN; Paynter, Jennifer J; Sou, Cindy C; Fourfouris, Tatiana T; Wang, Ying Y; Abraham, Ciril C; Ngo, Timothy T; Zhang, Yi Y; He, Linling L; Zhu, Jiang J
Publication Date: 2021-10-22

Variant appearance in text: TLR4: L18F
PubMed Link: 34669468
Variant Present in the following documents:
  • Main text
View BVdb publication page



Full-Length Recombinant hSP-D Binds and Inhibits SARS-CoV-2.

Biomolecules
Arroyo, Raquel R; Grant, Shawn N SN; Colombo, Miriam M; Salvioni, Lucia L; Corsi, Fabio F; Truffi, Marta M; Ottolina, Davide D; Hurst, Brett B; Salzberg, Marc M; Prosperi, Davide D; Kingma, Paul S PS
Publication Date: 2021-07-28

Variant appearance in text: TLR-4: L18F
PubMed Link: 34439781
Variant Present in the following documents:
  • Main text
  • biomolecules-11-01114.pdf
View BVdb publication page



Identification of Highly Conserved SARS-CoV-2 Antigenic Epitopes with Wide Coverage Using Reverse Vaccinology Approach.

Viruses
Hisham, Yasmin Y; Ashhab, Yaqoub Y; Hwang, Sang-Hyun SH; Kim, Dong-Eun DE
Publication Date: 2021-04-28

Variant appearance in text: TLR4: L18F
PubMed Link: 33925069
Variant Present in the following documents:
  • Main text
View BVdb publication page



Organoids as a new model for improving regenerative medicine and cancer personalized therapy in renal diseases.

Cell Death & Disease
Grassi, Ludovica L; Alfonsi, Romina R; Francescangeli, Federica F; Signore, Michele M; De Angelis, Maria Laura ML; Addario, Antonio A; Costantini, Manuela M; Flex, Elisabetta E; Ciolfi, Andrea A; Pizzi, Simone S; Bruselles, Alessandro A; Pallocca, Matteo M; Simone, Giuseppe G; Haoui, Mustapha M; Falchi, Mario M; Milella, Michele M; Sentinelli, Steno S; Di Matteo, Paola P; Stellacci, Emilia E; Gallucci, Michele M; Muto, Giovanni G; Tartaglia, Marco M; De Maria, Ruggero R; Bonci, Désirée D
Publication Date: 2019-02-27

Variant appearance in text: TLR4: 52C>T; Leu18Phe
PubMed Link: 30814510
Variant Present in the following documents:
  • 41419_2019_1453_MOESM27_ESM.xlsx, sheet 1
View BVdb publication page