TLR4 c.174C>G ;(p.N58K)

Variant ID: 9-120470921-C-G

NM_138554.4(TLR4):c.174C>G;(p.N58K)

This variant was identified in 2 publications

View GRCh38 version.




Publications:


MD-2 residues tyrosine 42, arginine 69, aspartic acid 122, and leucine 125 provide species specificity for lipid IVA.

The Journal Of Biological Chemistry
Meng, Jianmin J; Drolet, Joshua R JR; Monks, Brian G BG; Golenbock, Douglas T DT
Publication Date: 2010-09-03

Variant appearance in text: TLR4: N58K
PubMed Link: 20592019
Variant Present in the following documents:
  • Main text
View BVdb publication page



Novel roles of lysines 122, 125, and 58 in functional differences between human and murine MD-2.

Journal Of Immunology (Baltimore, Md. : 1950)
Vasl, Jozica J; Oblak, Alja A; Gioannini, Theresa L TL; Weiss, Jerrold P JP; Jerala, Roman R
Publication Date: 2009-10-15

Variant appearance in text: TLR4: N58K
PubMed Link: 19783674
Variant Present in the following documents:
  • Main text
View BVdb publication page