Alcohol, Intraocular Pressure, and Open-Angle Glaucoma: A Systematic Review and Meta-analysis.
Ophthalmology
Stuart, Kelsey V KV; Madjedi, Kian K; Luben, Robert N RN; Chua, Sharon Y L SYL; Warwick, Alasdair N AN; Chia, Mark M; Pasquale, Louis R LR; Wiggs, Janey L JL; Kang, Jae H JH; Hysi, Pirro G PG; Tran, Jessica H JH; Foster, Paul J PJ; Khawaja, Anthony P AP; ,
Association of TLR 9 gene polymorphisms with remission in patients with rheumatoid arthritis receiving TNF-α inhibitors and development of machine learning models.
Scientific Reports
Kim, Woorim W; Kim, Tae Hyeok TH; Oh, Soo Jin SJ; Kim, Hyun Jeong HJ; Kim, Joo Hee JH; Kim, Hyoun-Ah HA; Jung, Ju-Yang JY; Choi, In Ah IA; Lee, Kyung Eun KE
Germline Genetic Variants of Viral Entry and Innate Immunity May Influence Susceptibility to SARS-CoV-2 Infection: Toward a Polygenic Risk Score for Risk Stratification.
Frontiers In Immunology
Grolmusz, Vince Kornél VK; Bozsik, Anikó A; Papp, János J; Patócs, Attila A
Fibronectin extra domain A (FN-EDA) elevates intraocular pressure through Toll-like receptor 4 signaling.
Scientific Reports
Roberts, Amanda L AL; Mavlyutov, Timur A TA; Perlmutter, Tanisha E TE; Curry, Stacy M SM; Harris, Sherri L SL; Chauhan, Anil K AK; McDowell, Colleen M CM
Uric Acid Has Direct Proinflammatory Effects on Human Macrophages by Increasing Proinflammatory Mediators and Bacterial Phagocytosis Probably via URAT1.
Biomolecules
Martínez-Reyes, Camilo P CP; Manjarrez-Reyna, Aarón N AN; Méndez-García, Lucia A LA; Aguayo-Guerrero, José A JA; Aguirre-Sierra, Beatriz B; Villalobos-Molina, Rafael R; López-Vidal, Yolanda Y; Bobadilla, Karen K; Escobedo, Galileo G
Pleiotropic effect of the ABCG2 gene in gout: involvement in serum urate levels and progression from hyperuricemia to gout.
Arthritis Research & Therapy
Wrigley, Rebekah R; Phipps-Green, Amanda J AJ; Topless, Ruth K RK; Major, Tanya J TJ; Cadzow, Murray M; Riches, Philip P; Tausche, Anne-Kathrin AK; Janssen, Matthijs M; Joosten, Leo A B LAB; Jansen, Tim L TL; So, Alexander A; Harré Hindmarsh, Jennie J; Stamp, Lisa K LK; Dalbeth, Nicola N; Merriman, Tony R TR
Genetic Variability as a Regulator of TLR4 and NOD Signaling in Response to Bacterial Driven DNA Damage Response (DDR) and Inflammation: Focus on the Gastrointestinal (GI) Tract.
Frontiers In Genetics
Spanou, Evagelia E; Kalisperati, Polyxeni P; Pateras, Ioannis S IS; Papalampros, Alexandros A; Barbouti, Alexandra A; Tzioufas, Athanasios G AG; Kotsinas, Athanassios A; Sougioultzis, Stavros S
Genetic dissection of host immune response in pneumonia development and progression.
Scientific Reports
Smelaya, Tamara V TV; Belopolskaya, Olesya B OB; Smirnova, Svetlana V SV; Kuzovlev, Artem N AN; Moroz, Viktor V VV; Golubev, Arkadiy M AM; Pabalan, Noel A NA; Salnikova, Lyubov E LE
Association of Toll-like receptor 4 (TLR4) with chronic plaque type psoriasis and psoriatic arthritis.
Archives Of Dermatological Research
Smith, Rh Ll RL; Hébert, H L HL; Massey, J J; Bowes, J J; Marzo-Ortega, H H; Ho, P P; McHugh, N J NJ; Worthington, J J; Barton, A A; Griffiths, C E M CE; Warren, R B RB
The Toll-Like Receptor 4 (TLR4) Variant rs2149356 and Risk of Gout in European and Polynesian Sample Sets.
Plos One
Rasheed, Humaira H; McKinney, Cushla C; Stamp, Lisa K LK; Dalbeth, Nicola N; Topless, Ruth K RK; Day, Richard R; Kannangara, Diluk D; Williams, Kenneth K; Smith, Malcolm M; Janssen, Matthijs M; Jansen, Tim L TL; Joosten, Leo A LA; Radstake, Timothy R TR; Riches, Philip L PL; Tausche, Anne-Kathrin AK; Lioté, Frederic F; Lu, Leo L; Stahl, Eli A EA; Choi, Hyon K HK; So, Alexander A; Merriman, Tony R TR
Multiplicative interaction of functional inflammasome genetic variants in determining the risk of gout.
Arthritis Research & Therapy
McKinney, Cushla C; Stamp, Lisa K LK; Dalbeth, Nicola N; Topless, Ruth K RK; Day, Richard O RO; Kannangara, Diluk Rw DR; Williams, Kenneth M KM; Janssen, Matthijs M; Jansen, Timothy L TL; Joosten, Leo A LA; Radstake, Timothy R TR; Riches, Philip L PL; Tausche, Anne-Kathrin AK; Lioté, Frederic F; So, Alexander A; Merriman, Tony R TR
Polymorphisms of an innate immune gene, toll-like receptor 4, and aggressive prostate cancer risk: a systematic review and meta-analysis.
Plos One
Weng, Pei-Hsuan PH; Huang, Yi-Ling YL; Page, John H JH; Chen, Jen-Hau JH; Xu, Jianfeng J; Koutros, Stella S; Berndt, Sonja S; Chanock, Stephen S; Yeager, Meredith M; Witte, John S JS; Eeles, Rosalind A RA; Easton, Douglas F DF; Neal, David E DE; Donovan, Jenny J; Hamdy, Freddie C FC; Muir, Kenneth R KR; Giles, Graham G; Severi, Gianluca G; Smith, Jeffrey R JR; Balistreri, Carmela R CR; Shui, Irene M IM; Chen, Yen-Ching YC
Should a Toll-like receptor 4 (TLR-4) agonist or antagonist be designed to treat cancer? TLR-4: its expression and effects in the ten most common cancers.
Oncotargets And Therapy
Mai, Chun Wai CW; Kang, Yew Beng YB; Pichika, Mallikarjuna Rao MR
Association of inherited variation in Toll-like receptor genes with malignant melanoma susceptibility and survival.
Plos One
Gast, Andreas A; Bermejo, Justo Lorenzo JL; Claus, Rainer R; Brandt, Andreas A; Weires, Marianne M; Weber, Alexander A; Plass, Christoph C; Sucker, Antje A; Hemminki, Kari K; Schadendorf, Dirk D; Kumar, Rajiv R
Genetic variation in the toll-like receptor 4 and prostate cancer incidence and mortality.
The Prostate
Shui, Irene M IM; Stark, Jennifer R JR; Penney, Kathryn L KL; Schumacher, Fredrick R FR; Epstein, Mara M MM; Pitt, Michael J MJ; Stampfer, Meir J MJ; Tamimi, Rulla M RM; Lindstrom, Sara S; Sesso, Howard D HD; Fall, Katja K; Ma, Jing J; Kraft, Peter P; Giovannucci, Edward E; Mucci, Lorelei A LA
Polymorphisms in innate immunity genes and risk of childhood leukemia.
Human Immunology
Han, Sohee S; Lan, Qing Q; Park, Ae Kyung AK; Lee, Kyoung-Mu KM; Park, Sue K SK; Ahn, Hyo Seop HS; Shin, Hee Young HY; Kang, Hyoung Jin HJ; Koo, Hong Hoe HH; Seo, Jong Jin JJ; Choi, Ji Eun JE; Ahn, Yoon-Ok YO; Chanock, Stephen J SJ; Kim, Ho H; Rothman, Nathaniel N; Kang, Daehee D
Sequence variants in the TLR4 and TLR6-1-10 genes and prostate cancer risk. Results based on pooled analysis from three independent studies.
Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology
Lindström, Sara S; Hunter, David J DJ; Grönberg, Henrik H; Stattin, Pär P; Wiklund, Fredrik F; Xu, Jianfeng J; Chanock, Stephen J SJ; Hayes, Richard R; Kraft, Peter P
Association of common polymorphisms in IL10, and in other genes related to inflammatory response and obesity with colorectal cancer.
Cancer Causes & Control : Ccc
Tsilidis, Konstantinos K KK; Helzlsouer, Kathy J KJ; Smith, Michael W MW; Grinberg, Victoriya V; Hoffman-Bolton, Judith J; Clipp, Sandra L SL; Visvanathan, Kala K; Platz, Elizabeth A EA