TLR4 c.589_591delinsATG ;(p.V197M)

Variant ID: 9-120474995-GTT-ATG

NM_138554.4(TLR4):c.589_591delinsATG;(p.V197M)

This variant was identified in 4 publications

View GRCh38 version.




Publications:


Genetic variants determine intrafamilial variability of SARS-CoV-2 clinical outcomes in 19 Italian families.

Plos One
Azzarà, Alessia A; Cassano, Ilaria I; Paccagnella, Elisa E; Tirindelli, Maria Cristina MC; Nobile, Carolina C; Schittone, Valentina V; Lintas, Carla C; Sacco, Roberto R; Gurrieri, Fiorella F
Publication Date: 2022

Variant appearance in text: TLR4: Val197Met
PubMed Link: 36228008
Variant Present in the following documents:
  • Main text
  • pone.0275988.pdf
View BVdb publication page



Transmembrane protease serine 2 (TMPRSS2) rs75603675, comorbidity, and sex are the primary predictors of COVID-19 severity.

Life Science Alliance
Villapalos-García, Gonzalo G; Zubiaur, Pablo P; Rivas-Durán, Rebeca R; Campos-Norte, Pilar P; Arévalo-Román, Cristina C; Fernández-Rico, Marta M; García-Fraile Fraile, Lucio L; Fernández-Campos, Paula P; Soria-Chacartegui, Paula P; Fernández de Córdoba-Oñate, Sara S; Delgado-Wicke, Pablo P; Fernández-Ruiz, Elena E; González-Álvaro, Isidoro I; Sanz, Jesús J; Abad-Santos, Francisco F; de Los Santos, Ignacio I
Publication Date: 2022-10

Variant appearance in text: TLR4: Val197Met
PubMed Link: 35636966
Variant Present in the following documents:
  • Main text
View BVdb publication page



Human genetic basis of coronavirus disease 2019.

Signal Transduction And Targeted Therapy
Deng, Hao H; Yan, Xue X; Yuan, Lamei L
Publication Date: 2021-09-20

Variant appearance in text: TLR4: Val197Met
PubMed Link: 34545062
Variant Present in the following documents:
  • Main text
  • 41392_2021_Article_736.pdf
View BVdb publication page



SARS-CoV-2 infection: molecular mechanisms of severe outcomes to suggest therapeutics.

Expert Review Of Proteomics
Hartog, Nicholas N; Faber, William W; Frisch, Austin A; Bauss, Jacob J; Bupp, Caleb P CP; Rajasekaran, Surender S; Prokop, Jeremy W JW
Publication Date: 2021-02

Variant appearance in text: TLR4: Val197Met
PubMed Link: 33779460
Variant Present in the following documents:
  • Main text
View BVdb publication page