Publications:

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A novel mutation-proof, next-generation vaccine to fight against upcoming SARS-CoV-2 variants and subvariants, designed through AI enabled approaches and tools, along with the machine learning based immune simulation: A vaccine breakthrough.

International Journal Of Biological Macromolecules

Bhattacharya, Manojit M; Alshammari, Abdulrahman A; Alharbi, Metab M; Dhama, Kuldeep K; Lee, Sang-Soo SS; Chakraborty, Chiranjib C

Publication Date: 2023-05-17

Variant appearance in text: TLR4: L452R

PubMed Link: 37207746

Variant Present in the following documents:

• Main text
• main.pdf

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A performance comparison of heterostructure surface plasmon resonance biosensor for the diagnosis of novel coronavirus SARS-CoV-2.

Optical And Quantum Electronics

Akib, Tarik Bin Abdul TBA; Mostufa, Shahriar S; Rana, Md Masud MM; Hossain, Md Biplob MB; Islam, Md Rabiul MR

Publication Date: 2023

Variant appearance in text: TLR4: L452R

PubMed Link: 37008732

Variant Present in the following documents:

• 11082_2023_Article_4700.pdf

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Cross-variant proof predictive vaccine design based on SARS-CoV-2 spike protein using immunoinformatics approach.

Beni-Suef University Journal Of Basic And Applied Sciences

Sahu, Lavanya Kumar LK; Singh, Kiran K

Publication Date: 2023

Variant appearance in text: TLR4: L452R

PubMed Link: 36644779

Variant Present in the following documents:

• Main text
• 43088_2023_Article_341.pdf

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Candidate Multi-Epitope Vaccine against Corona B.1.617 Lineage: In Silico Approach.

Life (Basel, Switzerland)

Seadawy, Mohamed G MG; Zekri, Abdel Rahman N ARN; Saeed, Aya A AA; San, Emmanuel James EJ; Ageez, Amr M AM

Publication Date: 2022-10-27

Variant appearance in text: TLR4: L452R

PubMed Link: 36362871

Variant Present in the following documents:

• Main text
• life-12-01715.pdf

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Glycosylation in SARS-CoV-2 variants: A path to infection and recovery.

Biochemical Pharmacology

Aloor, Arya A; Aradhya, Rajaguru R; Venugopal, Parvathy P; Gopalakrishnan Nair, Bipin B; Suravajhala, Renuka R

Publication Date: 2022-12

Variant appearance in text: TLR4: L452R

PubMed Link: 36328134

Variant Present in the following documents:

• Main text

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The pathogenicity of COVID-19 and the role of pentraxin-3: An updated review study.

Pathology, Research And Practice

Margiana, Ria R; Sharma, Satish Kumar SK; Khan, Bilal Irshad BI; Alameri, Ameer A AA; Opulencia, Maria Jade Catalan MJC; Hammid, Ali Thaeer AT; Hamza, Thulfeqar Ahmed TA; Babakulov, Sharaf Khamrakulovich SK; Abdelbasset, Walid Kamal WK; Jawhar, Zanko Hassan ZH

Publication Date: 2022-09-15

Variant appearance in text: TLR4: L452R

PubMed Link: 36137396

Variant Present in the following documents:

• main.pdf

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Promising natural products against SARS-CoV-2: Structure, function, and clinical trials.

Phytotherapy Research : Ptr

Zhao, Yan Y; Deng, Shanshan S; Bai, Yujiao Y; Guo, Jinlin J; Kai, Guoyin G; Huang, Xinhe X; Jia, Xu X

Publication Date: 2022-10

Variant appearance in text: TLR4: L452R

PubMed Link: 35932157

Variant Present in the following documents:

• Main text

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SARS-CoV-2 and the central nervous system: Emerging insights into hemorrhage-associated neurological consequences and therapeutic considerations.

Ageing Research Reviews

Mitra, Joy J; Kodavati, Manohar M; Provasek, Vincent E VE; Rao, K S KS; Mitra, Sankar S; Hamilton, Dale J DJ; Horner, Philip J PJ; Vahidy, Farhaan S FS; Britz, Gavin W GW; Kent, Thomas A TA; Hegde, Muralidhar L ML

Publication Date: 2022-09

Variant appearance in text: TLR4: L452R

PubMed Link: 35843590

Variant Present in the following documents:

• Main text
• main.pdf

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A conserved subunit vaccine designed against SARS-CoV-2 variants showed evidence in neutralizing the virus.

Applied Microbiology And Biotechnology

Kibria, K M Kaderi KMK; Faruque, Md Omar MO; Islam, Md Shaid Bin MSB; Ullah, Hedayet H; Mahmud, Shafi S; Miah, Mojnu M; Saleh, Amani Ali AA

Publication Date: 2022-06

Variant appearance in text: TLR4: L452R

PubMed Link: 35612630

Variant Present in the following documents:

• Main text
• 253_2022_Article_11988.pdf

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Individual genetic variability mainly of Proinflammatory cytokines, cytokine receptors, and toll-like receptors dictates pathophysiology of COVID-19 disease.

Journal Of Medical Virology

Vakil, Mohammad Kazem MK; Mansoori, Yaser Y; Al-Awsi, Ghaidaa Raheem Lateef GRL; Hosseinipour, Ali A; Ahsant, Samaneh S; Ahmadi, Sedigheh S; Ekrahi, Mohammad M; Montaseri, Zahra Z; Pezeshki, Babak B; Mohaghegh, Poopak P; Sohrabpour, Mojtaba M; Bahmanyar, Maryam M; Daraei, Abdolreza A; Dadkhah Jouybari, Tahereh T; Tavassoli, Alireza A; Ghasemian, Abdolmajid A

Publication Date: 2022-09

Variant appearance in text: TLR4: L452R

PubMed Link: 35538614

Variant Present in the following documents:

• Main text
• JMV-94-4088.pdf

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Reverse vaccinology approach for multi-epitope centered vaccine design against delta variant of the SARS-CoV-2.

Environmental Science And Pollution Research International

Jalal, Khurshid K; Khan, Kanwal K; Basharat, Zarrin Z; Abbas, Muhammad Naseer MN; Uddin, Reaz R; Ali, Fawad F; Khan, Saeed Ahmad SA; Hassan, Syed Shams Ul SSU

Publication Date: 2022-08

Variant appearance in text: TLR4: L452R

PubMed Link: 35414157

Variant Present in the following documents:

• Main text
• 11356_2022_Article_19979.pdf

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Innate Immune Response in SARS-CoV-2 Infection.

Microorganisms

Schiuma, Giovanna G; Beltrami, Silvia S; Bortolotti, Daria D; Rizzo, Sabrina S; Rizzo, Roberta R

Publication Date: 2022-02-23

Variant appearance in text: TLR-4: L452R

PubMed Link: 35336077

Variant Present in the following documents:

• Main text
• microorganisms-10-00501.pdf

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Structural Comparison and Drug Screening of Spike Proteins of Ten SARS-CoV-2 Variants.

Research (Washington, D.C.)

Yang, Qiangzhen Q; Jian, Xuemin X; Syed, Ali Alamdar Shah AAS; Fahira, Aamir A; Zheng, Chenxiang C; Zhu, Zijia Z; Wang, Ke K; Zhang, Jinmai J; Wen, Yanqin Y; Li, Zhiqiang Z; Pan, Dun D; Lu, Tingting T; Wang, Zhuo Z; Shi, Yongyong Y

Publication Date: 2022

Variant appearance in text: TLR4: L452R

PubMed Link: 35198984

Variant Present in the following documents:

• RESEARCH2022-9781758.pdf

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In Silico Analyses on the Comparative Potential of Therapeutic Human Monoclonal Antibodies Against Newly Emerged SARS-CoV-2 Variants Bearing Mutant Spike Protein.

Frontiers In Immunology

Das, Nabarun Chandra NC; Chakraborty, Pritha P; Bayry, Jagadeesh J; Mukherjee, Suprabhat S

Publication Date: 2021

Variant appearance in text: TLR4: L452R

PubMed Link: 35082779

Variant Present in the following documents:

• Main text
• fimmu-12-782506.pdf

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Molecular Evolution of Severe Acute Respiratory Syndrome Coronavirus 2: Hazardous and More Hazardous Strains Behind the Coronavirus Disease 2019 Pandemic and Their Targeting by Drugs and Vaccines.

Frontiers In Cellular And Infection Microbiology

Tuli, Hardeep Singh HS; Sak, Katrin K; Aggarwal, Poonam P; Iqubal, Ashif A; Upadhaya, Sushil K SK; Kaur, Jagjit J; Kaur, Ginpreet G; Aggarwal, Diwakar D

Publication Date: 2021

Variant appearance in text: TLR-4: L452R

PubMed Link: 34970505

Variant Present in the following documents:

• Main text

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An update on host immunity correlates and prospects of re-infection in COVID-19.

International Reviews Of Immunology

Negi, Neema N; Maurya, Shesh Prakash SP; Singh, Ravinder R; Das, Bimal Kumar BK

Publication Date: 2021-12-28

Variant appearance in text: TLR4: L452R

PubMed Link: 34961403

Variant Present in the following documents:

• Main text

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An update on host immunity correlates and prospects of re-infection in COVID-19.

International Reviews Of Immunology

Negi, Neema N; Maurya, Shesh Prakash SP; Singh, Ravinder R; Das, Bimal Kumar BK

Publication Date: 2022

Variant appearance in text: TLR4: L452R

PubMed Link: 34961403

Variant Present in the following documents:

• Main text

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The Development of mRNA Vaccines for Infectious Diseases: Recent Updates.

Infection And Drug Resistance

Nitika, ; Wei, Jiao J; Hui, Ai-Min AM

Publication Date: 2021

Variant appearance in text: TLR-4: L452R

PubMed Link: 34916811

Variant Present in the following documents:

• Main text
• idr-14-5271.pdf

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Coronavirus Disease (COVID-19) Control between Drug Repurposing and Vaccination: A Comprehensive Overview.

Vaccines

Al-Karmalawy, Ahmed A AA; Soltane, Raya R; Abo Elmaaty, Ayman A; Tantawy, Mohamed A MA; Antar, Samar A SA; Yahya, Galal G; Chrouda, Amani A; Pashameah, Rami Adel RA; Mustafa, Muhamad M; Abu Mraheil, Mobarak M; Mostafa, Ahmed A

Publication Date: 2021-11-12

Variant appearance in text: TLR4: L452R

PubMed Link: 34835248

Variant Present in the following documents:

• Main text

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An update comprehensive review on the status of COVID-19: vaccines, drugs, variants and neurological symptoms.

Turkish Journal Of Biology = Turk Biyoloji Dergisi

Özkan Oktay, Ebru E; Tuncay, Salih S; Kaman, Tuğba T; Karasakal, Ömer Faruk ÖF; Özcan, Öznur Özge ÖÖ; Soylamiş, Tuğçe T; Karahan, Mesut M; Konuk, Muhsin M

Publication Date: 2021

Variant appearance in text: TLR4: L452R

PubMed Link: 34803439

Variant Present in the following documents:

• Main text
• turkjbio-45-342.pdf

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Comparative structural analyses of selected spike protein-RBD mutations in SARS-CoV-2 lineages.

Immunologic Research

Roy, Urmi U

Publication Date: 2021-11-16

Variant appearance in text: TLR4: L452R

PubMed Link: 34782989

Variant Present in the following documents:

• 12026_2021_Article_9250.pdf

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Comparative structural analyses of selected spike protein-RBD mutations in SARS-CoV-2 lineages.

Immunologic Research

Roy, Urmi U

Publication Date: 2022-04

Variant appearance in text: TLR4: L452R

PubMed Link: 34782989

Variant Present in the following documents:

• 12026_2021_Article_9250.pdf

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Application of omics technology to combat the COVID-19 pandemic.

Medcomm

Yang, Jingjing J; Yan, Yunzheng Y; Zhong, Wu W

Publication Date: 2021-09

Variant appearance in text: TLR4: L452R

PubMed Link: 34766152

Variant Present in the following documents:

• Main text
• MCO2-2-381.pdf

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Mechanism of a COVID-19 nanoparticle vaccine candidate that elicits a broadly neutralizing antibody response to SARS-CoV-2 variants.

Science Advances

Zhang, Yi-Nan YN; Paynter, Jennifer J; Sou, Cindy C; Fourfouris, Tatiana T; Wang, Ying Y; Abraham, Ciril C; Ngo, Timothy T; Zhang, Yi Y; He, Linling L; Zhu, Jiang J

Publication Date: 2021-10-22

Variant appearance in text: TLR4: L452R

PubMed Link: 34669468

Variant Present in the following documents:

• Main text

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Cheap and Commonplace: Making the Case for BCG and γδ T Cells in COVID-19.

Frontiers In Immunology

Morrison, Alexandra L AL; Sharpe, Sally S; White, Andrew D AD; Bodman-Smith, Mark M

Publication Date: 2021

Variant appearance in text: TLR4: L452R

PubMed Link: 34567010

Variant Present in the following documents:

• Main text
• fimmu-12-743924.pdf

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Control of SARS-CoV-2 infection after Spike DNA or Spike DNA+Protein co-immunization in rhesus macaques.

Plos Pathogens

Rosati, Margherita M; Agarwal, Mahesh M; Hu, Xintao X; Devasundaram, Santhi S; Stellas, Dimitris D; Chowdhury, Bhabadeb B; Bear, Jenifer J; Burns, Robert R; Donohue, Duncan D; Pessaint, Laurent L; Andersen, Hanne H; Lewis, Mark G MG; Terpos, Evangelos E; Dimopoulos, Meletios Athanasios MA; Wlodawer, Alexander A; Mullins, James I JI; Venzon, David J DJ; Pavlakis, George N GN; Felber, Barbara K BK

Publication Date: 2021-09

Variant appearance in text: TLR-4: L452R

PubMed Link: 34551020

Variant Present in the following documents:

• Main text

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Engineered SARS-CoV-2 receptor binding domain improves manufacturability in yeast and immunogenicity in mice.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Dalvie, Neil C NC; Rodriguez-Aponte, Sergio A SA; Hartwell, Brittany L BL; Tostanoski, Lisa H LH; Biedermann, Andrew M AM; Crowell, Laura E LE; Kaur, Kawaljit K; Kumru, Ozan S OS; Carter, Lauren L; Yu, Jingyou J; Chang, Aiquan A; McMahan, Katherine K; Courant, Thomas T; Lebas, Celia C; Lemnios, Ashley A AA; Rodrigues, Kristen A KA; Silva, Murillo M; Johnston, Ryan S RS; Naranjo, Christopher A CA; Tracey, Mary Kate MK; Brady, Joseph R JR; Whittaker, Charles A CA; Yun, Dongsoo D; Brunette, Natalie N; Wang, Jing Yang JY; Walkey, Carl C; Fiala, Brooke B; Kar, Swagata S; Porto, Maciel M; Lok, Megan M; Andersen, Hanne H; Lewis, Mark G MG; Love, Kerry R KR; Camp, Danielle L DL; Silverman, Judith Maxwell JM; Kleanthous, Harry H; Joshi, Sangeeta B SB; Volkin, David B DB; Dubois, Patrice M PM; Collin, Nicolas N; King, Neil P NP; Barouch, Dan H DH; Irvine, Darrell J DJ; Love, J Christopher JC

Publication Date: 2021-09-21

Variant appearance in text: TLR4: L452R

PubMed Link: 34493582

Variant Present in the following documents:

• Main text

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Risk Factors Associated with the Clinical Outcomes of COVID-19 and Its Variants in the Context of Cytokine Storm and Therapeutics/Vaccine Development Challenges.

Vaccines

Hanna, John J; Tipparaju, Padmavathi P; Mulherkar, Tania T; Lin, Edward E; Mischley, Victoria V; Kulkarni, Ratuja R; Bolton, Aliyah A; Byrareddy, Siddappa N SN; Jain, Pooja P

Publication Date: 2021-08-23

Variant appearance in text: TLR4: L452R

PubMed Link: 34452063

Variant Present in the following documents:

• Main text
• vaccines-09-00938.pdf

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An in-depth in silico and immunoinformatics approach for designing a potential multi-epitope construct for the effective development of vaccine to combat against SARS-CoV-2 encompassing variants of concern and interest.

Computers In Biology And Medicine

Saba, Abdullah Al AA; Adiba, Maisha M; Saha, Piyal P; Hosen, Md Ismail MI; Chakraborty, Sajib S; Nabi, A H M Nurun AHMN

Publication Date: 2021-09

Variant appearance in text: TLR4: L452R

PubMed Link: 34352457

Variant Present in the following documents:

• Main text
• main.pdf

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SARS-CoV-2: is there neuroinvasion?

Fluids And Barriers Of The Cns

McQuaid, Conor C; Brady, Molly M; Deane, Rashid R

Publication Date: 2021-07-14

Variant appearance in text: TLR4: L452R

PubMed Link: 34261487

Variant Present in the following documents:

• Main text

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Understanding COVID-19: are children the key?

Bmj Paediatrics Open

Warner, Suz S; Richter, Alex A; Stamataki, Zania Z; Kelly, Deirdre D

Publication Date: 2021

Variant appearance in text: TLR4: L452R

PubMed Link: 34192201

Variant Present in the following documents:

• Main text
• bmjpo-2021-001063.draft_revisions.pdf
• bmjpo-2021-001063.pdf

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SARS-CoV-2 and helminth co-infections, and environmental pollution exposure: An epidemiological and immunological perspective.

Environment International

Naidoo, Pragalathan P; Ghazi, Terisha T; Chuturgoon, Anil A AA; Naidoo, Rajen N RN; Ramsuran, Veron V; Mpaka-Mbatha, Miranda N MN; Bhengu, Khethiwe N KN; Nembe, Nomzamo N; Duma, Zamathombeni Z; Pillay, Roxanne R; Singh, Ravesh R; Mkhize-Kwitshana, Zilungile L ZL

Publication Date: 2021-11

Variant appearance in text: TLR4: L452R

PubMed Link: 34171587

Variant Present in the following documents:

• Main text
• main.pdf

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Increased burden of ultra-rare protein-altering variants among 4,877 individuals with schizophrenia.

Nature Neuroscience

Genovese, Giulio G; Fromer, Menachem M; Stahl, Eli A EA; Ruderfer, Douglas M DM; Chambert, Kimberly K; Landén, Mikael M; Moran, Jennifer L JL; Purcell, Shaun M SM; Sklar, Pamela P; Sullivan, Patrick F PF; Hultman, Christina M CM; McCarroll, Steven A SA

Publication Date: 2016-11

Variant appearance in text: TLR4: 1355T>G; Leu452Arg

PubMed Link: 27694994

Variant Present in the following documents:

• NIHMS815183-supplement-supp_table3.xlsx, sheet 1

View BVdb publication page

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