TLR4 c.2152_2153delinsGC ;(p.I718A)

Variant ID: 9-120476558-AT-GC

NM_138554.4(TLR4):c.2152_2153delinsGC;(p.I718A)

This variant was identified in 2 publications

View GRCh38 version.




Publications:


Targeting TLR4 signaling by TLR4 Toll/IL-1 receptor domain-derived decoy peptides: identification of the TLR4 Toll/IL-1 receptor domain dimerization interface.

Journal Of Immunology (Baltimore, Md. : 1950)
Toshchakov, Vladimir Y VY; Szmacinski, Henryk H; Couture, Leah A LA; Lakowicz, Joseph R JR; Vogel, Stefanie N SN
Publication Date: 2011-04-15

Variant appearance in text: TLR4: I718A
PubMed Link: 21402890
Variant Present in the following documents:
  • Main text
View BVdb publication page



A dimer of the Toll-like receptor 4 cytoplasmic domain provides a specific scaffold for the recruitment of signalling adaptor proteins.

Plos One
Núñez Miguel, Ricardo R; Wong, Joyce J; Westoll, Julian F JF; Brooks, Heather J HJ; O'Neill, Luke A J LA; Gay, Nicholas J NJ; Bryant, Clare E CE; Monie, Tom P TP
Publication Date: 2007-08-29

Variant appearance in text: TLR4: I718A
PubMed Link: 17726518
Variant Present in the following documents:
  • Main text
  • pone.0000788.pdf
View BVdb publication page