Integrated molecular drivers coordinate biological and clinical states in melanoma.
Nature Genetics
Conway, Jake R JR; Dietlein, Felix F; Taylor-Weiner, Amaro A; AlDubayan, Saud S; Vokes, Natalie N; Keenan, Tanya T; Reardon, Brendan B; He, Meng Xiao MX; Margolis, Claire A CA; Weirather, Jason L JL; Haq, Rizwan R; Schilling, Bastian B; Stephen Hodi, F F; Schadendorf, Dirk D; Liu, David D; Van Allen, Eliezer M EM
Profiling host ANP32A splicing landscapes to predict influenza A virus polymerase adaptation.
Nature Communications
Domingues, Patricia P; Eletto, Davide D; Magnus, Carsten C; Turkington, Hannah L HL; Schmutz, Stefan S; Zagordi, Osvaldo O; Lenk, Matthias M; Beer, Martin M; Stertz, Silke S; Hale, Benjamin G BG
Mini viral RNAs act as innate immune agonists during influenza virus infection.
Nature Microbiology
Te Velthuis, Aartjan J W AJW; Long, Joshua C JC; Bauer, David L V DLV; Fan, Rebecca L Y RLY; Yen, Hui-Ling HL; Sharps, Jane J; Siegers, Jurre Y JY; Killip, Marian J MJ; French, Hollie H; Oliva-Martín, Maria José MJ; Randall, Richard E RE; de Wit, Emmie E; van Riel, Debby D; Poon, Leo L M LLM; Fodor, Ervin E
Long-Term Culture of Distal Airway Epithelial Cells Allows Differentiation Towards Alveolar Epithelial Cells Suited for Influenza Virus Studies.
Ebiomedicine
Imai-Matsushima, Aki A; Martin-Sancho, Laura L; Karlas, Alexander A; Imai, Seiichiro S; Zoranovic, Tamara T; Hocke, Andreas C AC; Mollenkopf, Hans-Joachim HJ; Berger, Hilmar H; Meyer, Thomas F TF
Recurrent inactivating RASA2 mutations in melanoma.
Nature Genetics
Arafeh, Rand R; Qutob, Nouar N; Emmanuel, Rafi R; Keren-Paz, Alona A; Madore, Jason J; Elkahloun, Abdel A; Wilmott, James S JS; Gartner, Jared J JJ; Di Pizio, Antonella A; Winograd-Katz, Sabina S; Sindiri, Sivasish S; Rotkopf, Ron R; Dutton-Regester, Ken K; Johansson, Peter P; Pritchard, Antonia L AL; Waddell, Nicola N; Hill, Victoria K VK; Lin, Jimmy C JC; Hevroni, Yael Y; Rosenberg, Steven A SA; Khan, Javed J; Ben-Dor, Shifra S; Niv, Masha Y MY; Ulitsky, Igor I; Mann, Graham J GJ; Scolyer, Richard A RA; Hayward, Nicholas K NK; Samuels, Yardena Y
Influenza virus adaptation PB2-627K modulates nucleocapsid inhibition by the pathogen sensor RIG-I.
Cell Host & Microbe
Weber, Michaela M; Sediri, Hanna H; Felgenhauer, Ulrike U; Binzen, Ina I; Bänfer, Sebastian S; Jacob, Ralf R; Brunotte, Linda L; García-Sastre, Adolfo A; Schmid-Burgk, Jonathan L JL; Schmidt, Tobias T; Hornung, Veit V; Kochs, Georg G; Schwemmle, Martin M; Klenk, Hans-Dieter HD; Weber, Friedemann F
The novel human influenza A(H7N9) virus is naturally adapted to efficient growth in human lung tissue.
Mbio
Knepper, Jessica J; Schierhorn, Kristina L KL; Becher, Anne A; Budt, Matthias M; Tönnies, Mario M; Bauer, Torsten T TT; Schneider, Paul P; Neudecker, Jens J; Rückert, Jens C JC; Gruber, Achim D AD; Suttorp, Norbert N; Schweiger, Brunhilde B; Hippenstiel, Stefan S; Hocke, Andreas C AC; Wolff, Thorsten T
The multibasic cleavage site of the hemagglutinin of highly pathogenic A/Vietnam/1203/2004 (H5N1) avian influenza virus acts as a virulence factor in a host-specific manner in mammals.
Journal Of Virology
Suguitan, Amorsolo L AL; Matsuoka, Yumiko Y; Lau, Yuk-Fai YF; Santos, Celia P CP; Vogel, Leatrice L; Cheng, Lily I LI; Orandle, Marlene M; Subbarao, Kanta K