JAK2 c.674C>T ;(p.T225I)

Variant ID: 9-5054622-C-T

NM_004972.3(JAK2):c.674C>T;(p.T225I)

This variant was identified in 2 publications

View GRCh38 version.




Publications:


Base editing screens map mutations affecting interferon-γ signaling in cancer.

Cancer Cell
Coelho, Matthew A MA; Cooper, Sarah S; Strauss, Magdalena E ME; Karakoc, Emre E; Bhosle, Shriram S; Gonçalves, Emanuel E; Picco, Gabriele G; Burgold, Thomas T; Cattaneo, Chiara M CM; Veninga, Vivien V; Consonni, Sarah S; Dinçer, Cansu C; Vieira, Sara F SF; Gibson, Freddy F; Barthorpe, Syd S; Hardy, Claire C; Rein, Joel J; Thomas, Mark M; Marioni, John J; Voest, Emile E EE; Bassett, Andrew A; Garnett, Mathew J MJ
Publication Date: 2023-01-10

Variant appearance in text: JAK2: Thr225Ile
PubMed Link: 36669486
Variant Present in the following documents:
  • mmc4.xlsx, sheet 2
View BVdb publication page



PD-L1 targeting and subclonal immune escape mediated by PD-L1 mutations in metastatic colorectal cancer.

Journal For Immunotherapy Of Cancer
Stein, Alexander A; Simnica, Donjete D; Schultheiß, Christoph C; Scholz, Rebekka R; Tintelnot, Joseph J; Gökkurt, Eray E; von Wenserski, Lisa L; Willscher, Edith E; Paschold, Lisa L; Sauer, Markus M; Lorenzen, Sylvie S; Riera-Knorrenschild, Jorge J; Depenbusch, Reinhard R; Ettrich, Thomas J TJ; Dörfel, Steffen S; Al-Batran, Salah-Eddin SE; Karthaus, Meinolf M; Pelzer, Uwe U; Waberer, Lisa L; Hinke, Axel A; Bauer, Marcus M; Massa, Chiara C; Seliger, Barbara B; Wickenhauser, Claudia C; Bokemeyer, Carsten C; Hegewisch-Becker, Susanna S; Binder, Mascha M
Publication Date: 2021-07

Variant appearance in text: JAK2: 674C>T; Thr225Ile
PubMed Link: 34315821
Variant Present in the following documents:
  • jitc-2021-002844supp002.xlsx, sheet 1
View BVdb publication page