Publications:

Janus kinase 2 activation mechanisms revealed by analysis of suppressing mutations.

The Journal Of Allergy And Clinical Immunology

Hammarén, Henrik M HM; Virtanen, Anniina T AT; Abraham, Bobin George BG; Peussa, Heidi H; Hubbard, Stevan R SR; Silvennoinen, Olli O

Publication Date: 2019-04

Variant appearance in text: JAK2: G552A

PubMed Link: 30092288

Variant Present in the following documents:

• Main text

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ATP binding to the pseudokinase domain of JAK2 is critical for pathogenic activation.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Hammarén, Henrik M HM; Ungureanu, Daniela D; Grisouard, Jean J; Skoda, Radek C RC; Hubbard, Stevan R SR; Silvennoinen, Olli O

Publication Date: 2015-04-14

Variant appearance in text: JAK2: G552A

PubMed Link: 25825724

Variant Present in the following documents:

• Main text

View BVdb publication page