Publications:

Molecular basis for pseudokinase-dependent autoinhibition of JAK2 tyrosine kinase.

Nature Structural & Molecular Biology

Shan, Yibing Y; Gnanasambandan, Kavitha K; Ungureanu, Daniela D; Kim, Eric T ET; Hammarén, Henrik H; Yamashita, Kazuo K; Silvennoinen, Olli O; Shaw, David E DE; Hubbard, Stevan R SR

Publication Date: 2014-07

Variant appearance in text: JAK2: R588A

PubMed Link: 24918548

Variant Present in the following documents:

• Main text

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Ab initio modeling and experimental assessment of Janus Kinase 2 (JAK2) kinase-pseudokinase complex structure.

Plos Computational Biology

Wan, Xiaobo X; Ma, Yue Y; McClendon, Christopher L CL; Huang, Lily Jun-shen LJ; Huang, Niu N

Publication Date: 2013-04

Variant appearance in text: JAK2: R588A

PubMed Link: 23592968

Variant Present in the following documents:

• Main text
• pcbi.1003022.pdf

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JAK2 V617F constitutive activation requires JH2 residue F595: a pseudokinase domain target for specific inhibitors.

Plos One

Dusa, Alexandra A; Mouton, Céline C; Pecquet, Christian C; Herman, Murielle M; Constantinescu, Stefan N SN

Publication Date: 2010-06-16

Variant appearance in text: JAK2: R588A

PubMed Link: 20585391

Variant Present in the following documents:

• Main text
• pone.0011157.pdf

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