Publications:

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Structural basis of Janus kinase trans-activation.

Cell Reports

Caveney, Nathanael A NA; Saxton, Robert A RA; Waghray, Deepa D; Glassman, Caleb R CR; Tsutsumi, Naotaka N; Hubbard, Stevan R SR; Garcia, K Christopher KC

Publication Date: 2023-03-01

Variant appearance in text: JAK2: E592K

PubMed Link: 36867534

Variant Present in the following documents:

• Main text
• nihms-1887282.pdf

View BVdb publication page

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Identification of novel prognostic and predictive biomarkers in salivary duct carcinoma via comprehensive molecular profiling.

Npj Precision Oncology

Kohsaka, Shinji S; Tada, Yuichiro Y; Ando, Mizuo M; Nakaguro, Masato M; Shirai, Yukina Y; Ueno, Toshihide T; Kojima, Shinya S; Hirai, Hideaki H; Saigusa, Natsuki N; Kano, Satoshi S; Tsukahara, Kiyoaki K; Togashi, Takafumi T; Ozawa, Hiroyuki H; Kondo, Takahito T; Okami, Kenji K; Takahashi, Hideaki H; Kawakita, Daisuke D; Fushimi, Chihiro C; Suzuki, Takayoshi T; Shimizu, Akira A; Okamoto, Isaku I; Okada, Takuro T; Sato, Yuichiro Y; Imanishi, Yorihisa Y; Watanabe, Yoshihiro Y; Sakai, Akihiro A; Ebisumoto, Koji K; Sato, Yukiko Y; Urano, Makoto M; Honma, Yoshitaka Y; Yamazaki, Keisuke K; Ueki, Yushi Y; Hanazawa, Toyoyuki T; Saito, Yuki Y; Shimura, Tomotaka T; Nagao, Toshitaka T; Mano, Hiroyuki H

Publication Date: 2022-11-04

Variant appearance in text: JAK2: Glu592Lys

PubMed Link: 36333410

Variant Present in the following documents:

• 41698_2022_324_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

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Clinical impact of a cancer genomic profiling test using an in-house comprehensive targeted sequencing system.

Cancer Science

Hayashi, Hideyuki H; Tanishima, Shigeki S; Fujii, Kyoko K; Mori, Ryo R; Okada, Chihiro C; Yanagita, Emmy E; Shibata, Yuka Y; Matsuoka, Ryosuke R; Amano, Toraji T; Yamada, Takahiro T; Yabe, Ichiro I; Kinoshita, Ichiro I; Komatsu, Yoshito Y; Dosaka-Akita, Hirotoshi H; Nishihara, Hiroshi H

Publication Date: 2020-10

Variant appearance in text: JAK2: E592K

PubMed Link: 32772458

Variant Present in the following documents:

• CAS-111-3926-s001.xlsx, sheet 4
• CAS-111-3926-s001.xlsx, sheet 5

View BVdb publication page

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Mechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutations.

Science (New York, N.Y.)

Wilmes, Stephan S; Hafer, Maximillian M; Vuorio, Joni J; Tucker, Julie A JA; Winkelmann, Hauke H; Löchte, Sara S; Stanly, Tess A TA; Pulgar Prieto, Katiuska D KD; Poojari, Chetan C; Sharma, Vivek V; Richter, Christian P CP; Kurre, Rainer R; Hubbard, Stevan R SR; Garcia, K Christopher KC; Moraga, Ignacio I; Vattulainen, Ilpo I; Hitchcock, Ian S IS; Piehler, Jacob J

Publication Date: 2020-02-07

Variant appearance in text: JAK2: E592K

PubMed Link: 32029621

Variant Present in the following documents:

• Main text

View BVdb publication page

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Cell Dispersal Influences Tumor Heterogeneity and Introduces a Bias in NGS Data Interpretation.

Scientific Reports

Pongor, Lőrinc L; Harami-Papp, Hajnalka H; Méhes, Előd E; Czirók, András A; Győrffy, Balázs B

Publication Date: 2017-08-04

Variant appearance in text: JAK2: 1774G>A

PubMed Link: 28779157

Variant Present in the following documents:

• 41598_2017_7487_MOESM6_ESM.xls, sheet 1
• 41598_2017_7487_MOESM5_ESM.xls, sheet 4
• 41598_2017_7487_MOESM5_ESM.xls, sheet 1
• 41598_2017_7487_MOESM5_ESM.xls, sheet 5
• 41598_2017_7487_MOESM5_ESM.xls, sheet 3
• 41598_2017_7487_MOESM6_ESM.xls, sheet 2
• 41598_2017_7487_MOESM5_ESM.xls, sheet 2

View BVdb publication page

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A Landscape of Pharmacogenomic Interactions in Cancer.

Cell

Iorio, Francesco F; Knijnenburg, Theo A TA; Vis, Daniel J DJ; Bignell, Graham R GR; Menden, Michael P MP; Schubert, Michael M; Aben, Nanne N; Gonçalves, Emanuel E; Barthorpe, Syd S; Lightfoot, Howard H; Cokelaer, Thomas T; Greninger, Patricia P; van Dyk, Ewald E; Chang, Han H; de Silva, Heshani H; Heyn, Holger H; Deng, Xianming X; Egan, Regina K RK; Liu, Qingsong Q; Mironenko, Tatiana T; Mitropoulos, Xeni X; Richardson, Laura L; Wang, Jinhua J; Zhang, Tinghu T; Moran, Sebastian S; Sayols, Sergi S; Soleimani, Maryam M; Tamborero, David D; Lopez-Bigas, Nuria N; Ross-Macdonald, Petra P; Esteller, Manel M; Gray, Nathanael S NS; Haber, Daniel A DA; Stratton, Michael R MR; Benes, Cyril H CH; Wessels, Lodewyk F A LFA; Saez-Rodriguez, Julio J; McDermott, Ultan U; Garnett, Mathew J MJ

Publication Date: 2016-07-28

Variant appearance in text: JAK2: 1774G>A; E592K

PubMed Link: 27397505

Variant Present in the following documents:

• mmc3.xlsx, sheet 3

View BVdb publication page

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Individualized strategies to target specific mechanisms of disease in malignant melanoma patients displaying unique mutational signatures.

Oncotarget

Curiel-Olmo, Soraya S; García-Castaño, Almudena A; Vidal, Rebeca R; Pisonero, Helena H; Varela, Ignacio I; León-Castillo, Alicia A; Trillo, Eugenio E; González-Vela, Carmen C; García-Diaz, Nuria N; Almaraz, Carmen C; Moreno, Thaidy T; Cereceda, Laura L; Madureira, Rebeca R; Martinez, Nerea N; Ortiz-Romero, Pablo P; Valdizán, Elsa E; Piris, Miguel A MA; Vaqué, José P JP; Piris, Miguel M; Vaqué, José J

Publication Date: 2015-09-22

Variant appearance in text: JAK2: E592K

PubMed Link: 26327537

Variant Present in the following documents:

• oncotarget-06-25452-s003.xlsx, sheet 1

View BVdb publication page

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NCI-60 whole exome sequencing and pharmacological CellMiner analyses.

Plos One

Reinhold, William C WC; Varma, Sudhir S; Sousa, Fabricio F; Sunshine, Margot M; Abaan, Ogan D OD; Davis, Sean R SR; Reinhold, Spencer W SW; Kohn, Kurt W KW; Morris, Joel J; Meltzer, Paul S PS; Doroshow, James H JH; Pommier, Yves Y

Publication Date: 2014

Variant appearance in text: JAK2: E592K

PubMed Link: 25032700

Variant Present in the following documents:

• pone.0101670.s004.xlsx, sheet 1

View BVdb publication page

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Ab initio modeling and experimental assessment of Janus Kinase 2 (JAK2) kinase-pseudokinase complex structure.

Plos Computational Biology

Wan, Xiaobo X; Ma, Yue Y; McClendon, Christopher L CL; Huang, Lily Jun-shen LJ; Huang, Niu N

Publication Date: 2013-04

Variant appearance in text: JAK2: E592K

PubMed Link: 23592968

Variant Present in the following documents:

• Main text
• pcbi.1003022.pdf

View BVdb publication page

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