Structural basis of Janus kinase trans-activation.
Cell Reports
Caveney, Nathanael A NA; Saxton, Robert A RA; Waghray, Deepa D; Glassman, Caleb R CR; Tsutsumi, Naotaka N; Hubbard, Stevan R SR; Garcia, K Christopher KC
JAK2 ex13InDel drives oncogenic transformation and is associated with chronic eosinophilic leukemia and polycythemia vera.
Blood
Patel, Ami B AB; Franzini, Anca A; Leroy, Emilie E; Kim, Soo Jin SJ; Pomicter, Anthony D AD; Genet, Lidvine L; Xiao, Michael M; Yan, Dongqing D; Ahmann, Jonathan M JM; Agarwal, Archana M AM; Clair, Phillip P; Addada, Juanah J; Lambert, Jonathan J; Salmon, Matthew M; Gleich, Gerald J GJ; Cross, Nicholas C P NCP; Constantinescu, Stefan N SN; O'Hare, Thomas T; Prchal, Josef T JT; Deininger, Michael W MW
Uncoupling JAK2 V617F activation from cytokine-induced signalling by modulation of JH2 αC helix.
The Biochemical Journal
Leroy, Emilie E; Dusa, Alexandra A; Colau, Didier D; Motamedi, Amir A; Cahu, Xavier X; Mouton, Céline C; Huang, Lily J LJ; Shiau, Andrew K AK; Constantinescu, Stefan N SN