Publications:

ATP binding to the pseudokinase domain of JAK2 is critical for pathogenic activation.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Hammarén, Henrik M HM; Ungureanu, Daniela D; Grisouard, Jean J; Skoda, Radek C RC; Hubbard, Stevan R SR; Silvennoinen, Olli O

Publication Date: 2015-04-14

Variant appearance in text: JAK2: N678A

PubMed Link: 25825724

Variant Present in the following documents:

• Main text

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The pseudokinase domain of JAK2 is a dual-specificity protein kinase that negatively regulates cytokine signaling.

Nature Structural & Molecular Biology

Ungureanu, Daniela D; Wu, Jinhua J; Pekkala, Tuija T; Niranjan, Yashavanthi Y; Young, Clifford C; Jensen, Ole N ON; Xu, Chong-Feng CF; Neubert, Thomas A TA; Skoda, Radek C RC; Hubbard, Stevan R SR; Silvennoinen, Olli O

Publication Date: 2011-08-14

Variant appearance in text: JAK2: N678A

PubMed Link: 21841788

Variant Present in the following documents:

• Main text

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