Publications:

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Clinical features and prognosis of pediatric acute lymphocytic leukemia with JAK-STAT pathway genetic abnormalities: a case series.

Annals Of Hematology

Hu, Mengze M; Liu, Rong R; Li, Juanjuan J; Zhang, Lei L; Cao, Jing J; Yue, Mei M; Zhong, Dixiao D; Tang, Ruihong R

Publication Date: 2023-05-20

Variant appearance in text: JAK2: R683G

PubMed Link: 37209119

Variant Present in the following documents:

• Main text
• 277_2023_Article_5245.pdf

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Philadelphia-like acute lymphoblastic leukemia: the journey from molecular background to the role of bone marrow transplant-review article.

Annals Of Hematology

Alghandour, Reham R; Sakr, Doaa H DH; Shaaban, Yasmin Y

Publication Date: 2023-05-02

Variant appearance in text: JAK2: R683G

PubMed Link: 37129698

Variant Present in the following documents:

• Main text
• 277_2023_Article_5241.pdf

View BVdb publication page

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MD-ALL: an Integrative Platform for Molecular Diagnosis of B-cell Acute Lymphoblastic Leukemia.

Research Square

Gu, Zhaohui Z; Hu, Zunsong Z; Jia, Zhilian Z; Liu, Jiangyue J; Mao, Allen A; Han, Helen H

Publication Date: 2023-04-14

Variant appearance in text: JAK2: R683G

PubMed Link: 37090504

Variant Present in the following documents:

• nihpp-rs2798895v1.pdf

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Unmanipulated haploidentical hematopoietic stem cell transplantation for pediatric de novo acute megakaryoblastic leukemia without Down syndrome in China: A single-center study.

Frontiers In Oncology

Huang, Junbin J; Hu, Guanhua G; Suo, Pan P; Bai, Lu L; Cheng, Yifei Y; Wang, Yu Y; Zhang, XiaoHui X; Liu, KaiYan K; Sun, YuQian Y; Xu, LanPing L; Kong, Jun J; Yan, ChenHua C; Huang, Xiaojun X

Publication Date: 2023

Variant appearance in text: JAK2: R683G

PubMed Link: 36874138

Variant Present in the following documents:

• Main text
• fonc-13-1116205.pdf

View BVdb publication page

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A Phenogenetic Axis that Modulates Clinical Manifestation and Predicts Treatment Outcome in Primary Myeloid Neoplasms.

Cancer Research Communications

Shen, Qiujin Q; Feng, Yahui Y; Gong, Xiaowen X; Jia, Yujiao Y; Gao, Qingyan Q; Jiao, Xiaokang X; Qi, Saibing S; Liu, Xueou X; Wei, Hui H; Huang, Bingqing B; Zhao, Ningning N; Song, Xiaoqiang X; Ma, Yueshen Y; Liang, Shihao S; Zhang, Donglei D; Qin, Li L; Wang, Ying Y; Qu, Shiqiang S; Zou, Yao Y; Chen, Yumei Y; Guo, Ye Y; Yi, Shuhua S; An, Gang G; Jiao, Zengtao Z; Zhang, Song S; Li, Linfeng L; Yan, Jun J; Wang, Huijun H; Song, Zhen Z; Mi, Yingchang Y; Qiu, Lugui L; Zhu, Xiaofan X; Wang, Jianxiang J; Xiao, Zhijian Z; Chen, Junren J

Publication Date: 2022-04

Variant appearance in text: JAK2: 2047A>G; R683G

PubMed Link: 36873623

Variant Present in the following documents:

• crc-21-0194-s05.xlsx, sheet 1

View BVdb publication page

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CAR-T cell therapy followed by allogenic hematopoietic stem cell transplantation yielded comparable outcome between Ph like ALL and other high-risk ALL.

Biomarker Research

Dai, Hai-Ping HP; Kong, Dan-Qing DQ; Shen, Hong-Jie HJ; Cui, Wei W; Wang, Qian Q; Li, Zheng Z; Yin, Jia J; Kang, Li-Qing LQ; Yu, Lei L; Wu, De-Pei DP; Tang, Xiao-Wen XW

Publication Date: 2023-02-15

Variant appearance in text: JAK2: R683G

PubMed Link: 36793095

Variant Present in the following documents:

• 40364_2023_Article_451.pdf

View BVdb publication page

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Dynamics of age- versus therapy-related clonal hematopoiesis in long-term survivors of pediatric cancer.

Cancer Discovery

Hagiwara, Kohei K; Natarajan, Sivaraman S; Wang, Zhaoming Z; Zubair, Haseeb H; Mulder, Heather L HL; Dong, Li L; Plyler, Emily M EM; Thimmaiah, Padma P; Ma, Xiaotu X; Ness, Kirsten K KK; Li, Zhenghong Z; Mulrooney, Daniel A DA; Wilson, Carmen L CL; Yasui, Yutaka Y; Hudson, Melissa M MM; Easton, John J; Robison, Leslie L LL; Zhang, Jinghui J

Publication Date: 2023-02-08

Variant appearance in text: JAK2: R683G

PubMed Link: 36751942

Variant Present in the following documents:

• cd-22-0956_tables_s2_s7_s8_s9_suppst1.xlsx, sheet 4
• cd-22-0956_tables_s2_s7_s8_s9_suppst1.xlsx, sheet 2
• cd-22-0956_tables_s2_s7_s8_s9_suppst1.xlsx, sheet 1

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Spectrum and clinical features of gene mutations in Chinese pediatric acute lymphoblastic leukemia.

Bmc Pediatrics

Shen, Diying D; Liu, Lixia L; Xu, Xiaojun X; Song, Hua H; Zhang, Jingying J; Xu, Weiqun W; Zhao, Fenying F; Liang, Juan J; Liao, Chan C; Wang, Yan Y; Xia, Tian T; Wang, Chengcheng C; Lou, Feng F; Cao, Shanbo S; Qin, Jiayue J; Tang, Yongmin Y

Publication Date: 2023-02-04

Variant appearance in text: JAK2: 2047A>G; R683G

PubMed Link: 36739388

Variant Present in the following documents:

• 12887_2023_3856_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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TSLP as a Potential Therapy in the Treatment of CRLF2 B Cell Acute Lymphoblastic Leukemia.

International Journal Of Molecular Sciences

Alkashgari, Hossam R HR; Ruiz-Jimenez, Caleb C; Stoian, Cornelia C; Coats, Jacqueline S JS; Baez, Ineavely I; Chirshev, Evgeny E; Martinez, Shannalee R SR; Dovat, Sinisa S; Francis-Boyle, Olivia L OL; Casiano, Carlos A CA; Payne, Kimberly J KJ

Publication Date: 2022-12-28

Variant appearance in text: JAK2: R683G

PubMed Link: 36613920

Variant Present in the following documents:

• Main text
• ijms-24-00474.pdf

View BVdb publication page

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Integrative genomic analysis of childhood acute lymphoblastic leukaemia lacking a genetic biomarker in the UKALL2003 clinical trial.

Leukemia

Schwab, Claire C; Cranston, Ruth E RE; Ryan, Sarra L SL; Butler, Ellie E; Winterman, Emily E; Hawking, Zoe Z; Bashton, Matthew M; Enshaei, Amir A; Russell, Lisa J LJ; Kingsbury, Zoya Z; Peden, John F JF; Barretta, Emilio E; Murray, James J; Gibson, Jude J; Hinchliffe, Andrew C AC; Bain, Robert R; Vora, Ajay A; Bentley, David R DR; Ross, Mark T MT; Moorman, Anthony V AV; Harrison, Christine J CJ

Publication Date: 2022-12-22

Variant appearance in text: JAK2: R683G

PubMed Link: 36550215

Variant Present in the following documents:

• 41375_2022_1799_MOESM1_ESM.pdf

View BVdb publication page

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Transcriptome-based molecular subtypes and differentiation hierarchies improve the classification framework of acute myeloid leukemia.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Cheng, Wen-Yan WY; Li, Jian-Feng JF; Zhu, Yong-Mei YM; Lin, Xiang-Jie XJ; Wen, Li-Jun LJ; Zhang, Fan F; Zhang, Yu-Liang YL; Zhao, Ming M; Fang, Hai H; Wang, Sheng-Yue SY; Lin, Xiao-Jing XJ; Qiao, Niu N; Yin, Wei W; Zhang, Jia-Nan JN; Dai, Yu-Ting YT; Jiang, Lu L; Sun, Xiao-Jian XJ; Xu, Yi Y; Zhang, Tong-Tong TT; Chen, Su-Ning SN; Zhu, Hong-Hu HH; Chen, Zhu Z; Jin, Jie J; Wu, De-Pei DP; Shen, Yang Y; Chen, Sai-Juan SJ

Publication Date: 2022-12-06

Variant appearance in text: JAK2: 2047A>G; Arg683Gly

PubMed Link: 36442087

Variant Present in the following documents:

• pnas.2211429119.sd02.xlsx, sheet 1

View BVdb publication page

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The kinetics of blast clearance are associated with copy number alterations in childhood B-cell acute lymphoblastic leukemia.

Neoplasia (New York, N.Y.)

Urbańska, Zuzanna Z; Lejman, Monika M; Taha, Joanna J; Madzio, Joanna J; Ostrowska, Kinga K; Miarka-Walczyk, Karolina K; Wypyszczak, Kamila K; Styka, Borys B; Jakubowska, Justyna J; Sędek, Łukasz Ł; Szczepański, Tomasz T; Stańczak, Marcin M; Fendler, Wojciech W; Młynarski, Wojciech W; Pastorczak, Agata A

Publication Date: 2022-10-23

Variant appearance in text: JAK2: 2047A>G; Arg683Gly

PubMed Link: 36288679

Variant Present in the following documents:

• Main text
• main.pdf

View BVdb publication page

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JAK2 Alterations in Acute Lymphoblastic Leukemia: Molecular Insights for Superior Precision Medicine Strategies.

Frontiers In Cell And Developmental Biology

Downes, Charlotte Ej CE; McClure, Barbara J BJ; McDougal, Daniel P DP; Heatley, Susan L SL; Bruning, John B JB; Thomas, Daniel D; Yeung, David T DT; White, Deborah L DL

Publication Date: 2022

Variant appearance in text: JAK2: R683G

PubMed Link: 35903543

Variant Present in the following documents:

• Main text
• fcell-10-942053.pdf

View BVdb publication page

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Suspicions regarding the genetic inheritance of acute lymphoblastic leukemia in patients with down syndrome.

Journal Of Mother And Child

Behluli, Emir E; Nuhii, Nexhibe N; Liehr, Thomas T; Temaj, Gazmend G

Publication Date: 2022-07-20

Variant appearance in text: JAK2: R683G

PubMed Link: 35853737

Variant Present in the following documents:

• Main text
• jmotherandchild-26-1-jmotherandchild.20222601.d-22-00002.pdf

View BVdb publication page

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Genome-wide analyses of 200,453 individuals yield new insights into the causes and consequences of clonal hematopoiesis.

Nature Genetics

Kar, Siddhartha P SP; Quiros, Pedro M PM; Gu, Muxin M; Jiang, Tao T; Mitchell, Jonathan J; Langdon, Ryan R; Iyer, Vivek V; Barcena, Clea C; Vijayabaskar, M S MS; Fabre, Margarete A MA; Carter, Paul P; Petrovski, Slavé S; Burgess, Stephen S; Vassiliou, George S GS

Publication Date: 2022-08

Variant appearance in text: JAK2: R683G

PubMed Link: 35835912

Variant Present in the following documents:

• 41588_2022_1121_MOESM3_ESM.xlsx, sheet 3

View BVdb publication page

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Outcomes of allogeneic hematopoietic cell transplantation in adults with fusions associated with Ph-like ALL.

Blood Advances

Aldoss, Ibrahim I; Yang, Dongyun D; Tomasian, Vanina V; Mokhtari, Sally S; Jackson, Ryan R; Gu, Zhaohui Z; Telatar, Milhan M; Yew, Hooi H; Al Malki, Monzr M MM; Salhotra, Amandeep A; Khaled, Samer S; Ali, Haris H; Aribi, Ahmed A; Sandhu, Karamjeet S KS; Mei, Matthew M; Arslan, Shukaib S; Koller, Paul P; Artz, Andrew A; Aoun, Patricia P; Gu, Dongqing D; Snyder, David D; Stewart, Forrest M FM; Curtin, Peter P; Stein, Anthony S AS; Pillai, Raju R; Marcucci, Guido G; Forman, Stephen J SJ; Pullarkat, Vinod V; Nakamura, Ryotaro R; Afkhami, Michelle M

Publication Date: 2022-09-13

Variant appearance in text: JAK2: 2047A>G; R683G

PubMed Link: 35816633

Variant Present in the following documents:

• advancesADV2022007597-suppl1.xlsx, sheet 1

View BVdb publication page

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Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma.

Nature Communications

Gounder, Mrinal M MM; Agaram, Narasimhan P NP; Trabucco, Sally E SE; Robinson, Victoria V; Ferraro, Richard A RA; Millis, Sherri Z SZ; Krishnan, Anita A; Lee, Jessica J; Attia, Steven S; Abida, Wassim W; Drilon, Alexander A; Chi, Ping P; Angelo, Sandra P D' SP; Dickson, Mark A MA; Keohan, Mary Lou ML; Kelly, Ciara M CM; Agulnik, Mark M; Chawla, Sant P SP; Choy, Edwin E; Chugh, Rashmi R; Meyer, Christian F CF; Myer, Parvathi A PA; Moore, Jessica L JL; Okimoto, Ross A RA; Pollock, Raphael E RE; Ravi, Vinod V; Singh, Arun S AS; Somaiah, Neeta N; Wagner, Andrew J AJ; Healey, John H JH; Frampton, Garrett M GM; Venstrom, Jeffrey M JM; Ross, Jeffrey S JS; Ladanyi, Marc M; Singer, Samuel S; Brennan, Murray F MF; Schwartz, Gary K GK; Lazar, Alexander J AJ; Thomas, David M DM; Maki, Robert G RG; Tap, William D WD; Ali, Siraj M SM; Jin, Dexter X DX

Publication Date: 2022-06-15

Variant appearance in text: JAK2: R683G

PubMed Link: 35705558

Variant Present in the following documents:

• 41467_2022_30496_MOESM2_ESM.xls, sheet 1

View BVdb publication page

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IRF4 deficiency vulnerates B-cell progeny for leukemogenesis via somatically acquired Jak3 mutations conferring IL-7 hypersensitivity.

Cell Death And Differentiation

Das Gupta, Dennis D; Paul, Christoph C; Samel, Nadine N; Bieringer, Maria M; Staudenraus, Daniel D; Marini, Federico F; Raifer, Hartmann H; Menke, Lisa L; Hansal, Lea L; Camara, Bärbel B; Roth, Edith E; Daum, Patrick P; Wanzel, Michael M; Mernberger, Marco M; Nist, Andrea A; Bauer, Uta-Maria UM; Helmprobst, Frederik F; Buchholz, Malte M; Roth, Katrin K; Bastian, Lorenz L; Hartmann, Alina M AM; Baldus, Claudia C; Ikuta, Koichi K; Neubauer, Andreas A; Burchert, Andreas A; Jäck, Hans-Martin HM; Klein, Matthias M; Bopp, Tobias T; Stiewe, Thorsten T; Pagenstecher, Axel A; Lohoff, Michael M

Publication Date: 2022-11

Variant appearance in text: JAK2: R683G

PubMed Link: 35459909

Variant Present in the following documents:

• Main text
• 41418_2022_Article_1005.pdf

View BVdb publication page

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Simultaneous monitoring of disease and microbe dynamics through plasma DNA sequencing in pediatric patients with acute lymphoblastic leukemia.

Science Advances

Barsan, Valentin V; Xia, Yuntao Y; Klein, David D; Gonzalez-Pena, Veronica V; Youssef, Sarah S; Inaba, Yuki Y; Mahmud, Ousman O; Natarajan, Sivaraman S; Agarwal, Vibhu V; Pang, Yakun Y; Autry, Robert R; Pui, Ching-Hon CH; Inaba, Hiroto H; Evans, William W; Gawad, Charles C

Publication Date: 2022-04-22

Variant appearance in text: JAK2: R683G

PubMed Link: 35442732

Variant Present in the following documents:

• sciadv.abj1360.pdf

View BVdb publication page

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An alternative CYB5A transcript is expressed in aneuploid ALL and enriched in relapse.

Bmc Genomic Data

Bartsch, Lorenz L; Schroeder, Michael P MP; Hänzelmann, Sonja S; Bastian, Lorenz L; Lázaro-Navarro, Juan J; Schlee, Cornelia C; Tanchez, Jutta Ortiz JO; Schulze, Veronika V; Isaakidis, Konstandina K; Rieger, Michael A MA; Gökbuget, Nicola N; Eckert, Cornelia C; Serve, Hubert H; Horstmann, Martin M; Schrappe, Martin M; Brüggemann, Monika M; Baldus, Claudia D CD; Neumann, Martin M

Publication Date: 2022-04-18

Variant appearance in text: JAK2: R683G

PubMed Link: 35436854

Variant Present in the following documents:

• 12863_2022_1041_MOESM15_ESM.xlsx, sheet 2

View BVdb publication page

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Distinct genomic landscape of Chinese pediatric acute myeloid leukemia impacts clinical risk classification.

Nature Communications

Liu, Ting T; Rao, Jianan J; Hu, Wenting W; Cui, Bowen B; Cai, Jiaoyang J; Liu, Yuhan Y; Sun, Huiying H; Chen, Xiaoxiao X; Tang, Yanjing Y; Chen, Jing J; Wang, Xiang X; Wang, Han H; Qian, Wubin W; Mao, Binchen B; Guo, Sheng S; Wang, Ronghua R; Liu, Yu Y; Shen, Shuhong S

Publication Date: 2022-03-28

Variant appearance in text: JAK2: R683G

PubMed Link: 35347147

Variant Present in the following documents:

• 41467_2022_29336_MOESM8_ESM.xlsx, sheet 1

View BVdb publication page

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Integrated Genomic Analysis Identifies UBTF Tandem Duplications as a Recurrent Lesion in Pediatric Acute Myeloid Leukemia.

Blood Cancer Discovery

Umeda, Masayuki M; Ma, Jing J; Huang, Benjamin J BJ; Hagiwara, Kohei K; Westover, Tamara T; Abdelhamed, Sherif S; Barajas, Juan M JM; Thomas, Melvin E ME; Walsh, Michael P MP; Song, Guangchun G; Tian, Liqing L; Liu, Yanling Y; Chen, Xiaolong X; Kolekar, Pandurang P; Tran, Quang Q; Foy, Scott G SG; Maciaszek, Jamie L JL; Kleist, Andrew B AB; Leonti, Amanda R AR; Ju, Bengsheng B; Easton, John J; Wu, Huiyun H; Valentine, Virginia V; Valentine, Marcus B MB; Liu, Yen-Chun YC; Ries, Rhonda E RE; Smith, Jenny L JL; Parganas, Evan E; Iacobucci, Ilaria I; Hiltenbrand, Ryan R; Miller, Jonathan J; Myers, Jason R JR; Rampersaud, Evadnie E; Rahbarinia, Delaram D; Rusch, Michael M; Wu, Gang G; Inaba, Hiroto H; Wang, Yi-Cheng YC; Alonzo, Todd A TA; Downing, James R JR; Mullighan, Charles G CG; Pounds, Stanley S; Babu, M Madan MM; Zhang, Jinghui J; Rubnitz, Jeffrey E JE; Meshinchi, Soheil S; Ma, Xiaotu X; Klco, Jeffery M JM

Publication Date: 2022-05-05

Variant appearance in text: JAK2: R683G

PubMed Link: 35176137

Variant Present in the following documents:

• bcd-21-0160_supplemental_tables_supp1-32.xlsx, sheet 18

View BVdb publication page

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Potent, p53-independent induction of NOXA sensitizes MLL-rearranged B-cell acute lymphoblastic leukemia cells to venetoclax.

Oncogene

Fidyt, Klaudyna K; Pastorczak, Agata A; Cyran, Julia J; Crump, Nicholas T NT; Goral, Agnieszka A; Madzio, Joanna J; Muchowicz, Angelika A; Poprzeczko, Martyna M; Domka, Krzysztof K; Komorowski, Lukasz L; Winiarska, Magdalena M; Harman, Joe R JR; Siudakowska, Karolina K; Graczyk-Jarzynka, Agnieszka A; Patkowska, Elzbieta E; Lech-Maranda, Ewa E; Mlynarski, Wojciech W; Golab, Jakub J; Milne, Thomas A TA; Firczuk, Malgorzata M

Publication Date: 2022-03

Variant appearance in text: JAK2: R683G

PubMed Link: 35091682

Variant Present in the following documents:

• 41388_2022_2196_MOESM1_ESM.pdf

View BVdb publication page

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Whole-transcriptome analysis in acute lymphoblastic leukemia: a report from the DFCI ALL Consortium Protocol 16-001.

Blood Advances

Tran, Thai Hoa TH; Langlois, Sylvie S; Meloche, Caroline C; Caron, Maxime M; Saint-Onge, Pascal P; Rouette, Alexandre A; Bataille, Alain R AR; Jimenez-Cortes, Camille C; Sontag, Thomas T; Bittencourt, Henrique H; Laverdière, Caroline C; Lavallée, Vincent-Philippe VP; Leclerc, Jean-Marie JM; Cole, Peter D PD; Gennarini, Lisa M LM; Kahn, Justine M JM; Kelly, Kara M KM; Michon, Bruno B; Santiago, Raoul R; Stevenson, Kristen E KE; Welch, Jennifer J G JJG; Schroeder, Kaitlin M KM; Koch, Victoria V; Cellot, Sonia S; Silverman, Lewis B LB; Sinnett, Daniel D

Publication Date: 2022-02-22

Variant appearance in text: JAK2: R683G

PubMed Link: 34933343

Variant Present in the following documents:

• advancesADV2021005634-suppl1.xlsx, sheet 3

View BVdb publication page

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Transcriptional and Mutational Profiling of B-Other Acute Lymphoblastic Leukemia for Improved Diagnostics.

Cancers

Chouvarine, Philippe P; Antić, Željko Ž; Lentes, Jana J; Schröder, Charlotte C; Alten, Julia J; Brüggemann, Monika M; Carrillo-de Santa Pau, Enrique E; Illig, Thomas T; Laguna, Teresa T; Schewe, Denis D; Stanulla, Martin M; Tang, Ming M; Zimmermann, Martin M; Schrappe, Martin M; Schlegelberger, Brigitte B; Cario, Gunnar G; Bergmann, Anke K AK

Publication Date: 2021-11-12

Variant appearance in text: JAK2: R683G

PubMed Link: 34830809

Variant Present in the following documents:

• Main text

View BVdb publication page

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IKZF1 deletions associate with CRLF2 overexpression leading to a poor prognosis in B-cell precursor acute lymphoblastic leukaemia.

Translational Oncology

Maciel, Ana Luiza Tardem ALT; Barbosa, Thayana da Conceição TDC; Blunck, Caroline Barbieri CB; Wolch, Karolyne K; Machado, Amanda de Albuquerque Lopes AAL; da Costa, Elaine Sobral ES; Bergier, Lavínia Lustosa LL; Schramm, Márcia Trindade MT; Ikoma-Coltutato, Maura Rosane Valério MRV; Lins, Mecneide Mendes MM; Aguiar, Thais Ferraz TF; Mansur, Marcela Braga MB; Emerenciano, Mariana M

Publication Date: 2022-01

Variant appearance in text: JAK2: R683G

PubMed Link: 34826720

Variant Present in the following documents:

• Main text
• main.pdf

View BVdb publication page

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IKZF1 deletions associate with CRLF2 overexpression leading to a poor prognosis in B-cell precursor acute lymphoblastic leukaemia.

Translational Oncology

Maciel, Ana Luiza Tardem ALT; Barbosa, Thayana da Conceição TDC; Blunck, Caroline Barbieri CB; Wolch, Karolyne K; Machado, Amanda de Albuquerque Lopes AAL; da Costa, Elaine Sobral ES; Bergier, Lavínia Lustosa LL; Schramm, Márcia Trindade MT; Ikoma-Coltutato, Maura Rosane Valério MRV; Lins, Mecneide Mendes MM; Aguiar, Thais Ferraz TF; Mansur, Marcela Braga MB; Emerenciano, Mariana M

Publication Date: 2021-11-23

Variant appearance in text: JAK2: R683G

PubMed Link: 34826720

Variant Present in the following documents:

• Main text
• main.pdf

View BVdb publication page

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Integrative Genomic Analysis of Pediatric Myeloid-Related Acute Leukemias Identifies Novel Subtypes and Prognostic Indicators.

Blood Cancer Discovery

Fornerod, Maarten M; Ma, Jing J; Noort, Sanne S; Liu, Yu Y; Walsh, Michael P MP; Shi, Lei L; Nance, Stephanie S; Liu, Yanling Y; Wang, Yuanyuan Y; Song, Guangchun G; Lamprecht, Tamara T; Easton, John J; Mulder, Heather L HL; Yergeau, Donald D; Myers, Jacquelyn J; Kamens, Jennifer L JL; Obeng, Esther A EA; Pigazzi, Martina M; Jarosova, Marie M; Kelaidi, Charikleia C; Polychronopoulou, Sophia S; Lamba, Jatinder K JK; Baker, Sharyn D SD; Rubnitz, Jeffrey E JE; Reinhardt, Dirk D; van den Heuvel-Eibrink, Marry M MM; Locatelli, Franco F; Hasle, Henrik H; Klco, Jeffery M JM; Downing, James R JR; Zhang, Jinghui J; Pounds, Stanley S; Zwaan, C Michel CM; Gruber, Tanja A TA; , ; , ; , ; , ; , ; ,

Publication Date: 2021-11

Variant appearance in text: JAK2: R683G

PubMed Link: 34778799

Variant Present in the following documents:

• bloodcandisc-2-586-s001.xlsx, sheet 11

View BVdb publication page

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Janus Kinase Signaling: Oncogenic Criminal of Lymphoid Cancers.

Cancers

Li, Boheng B; Wan, Qin Q; Li, Zhubo Z; Chng, Wee-Joo WJ

Publication Date: 2021-10-14

Variant appearance in text: JAK2: R683G

PubMed Link: 34680295

Variant Present in the following documents:

• Main text

View BVdb publication page

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Recent Advances in Molecular Diagnostics and Targeted Therapy of Myeloproliferative Neoplasms.

Cancers

Stivala, Simona S; Meyer, Sara C SC

Publication Date: 2021-10-09

Variant appearance in text: JAK2: R683G

PubMed Link: 34680185

Variant Present in the following documents:

• Main text
• cancers-13-05035.pdf

View BVdb publication page

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: JAK2: R683G

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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Analysis of acute lymphoblastic leukemia drug sensitivity by changes in impedance via stromal cell adherence.

Plos One

Luong, Annie A; Cerignoli, Fabio F; Abassi, Yama Y; Heisterkamp, Nora N; Abdel-Azim, Hisham H

Publication Date: 2021

Variant appearance in text: JAK2: R683G

PubMed Link: 34591931

Variant Present in the following documents:

• Main text
• pone.0258140.pdf

View BVdb publication page

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Integration of Molecular Information in Risk Assessment of Patients with Myeloproliferative Neoplasms.

Cells

Loscocco, Giuseppe G GG; Coltro, Giacomo G; Guglielmelli, Paola P; Vannucchi, Alessandro M AM

Publication Date: 2021-08-02

Variant appearance in text: JAK2: R683G

PubMed Link: 34440731

Variant Present in the following documents:

• Main text
• cells-10-01962.pdf

View BVdb publication page

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Single-Cell RNA-Seq of T Cells in B-ALL Patients Reveals an Exhausted Subset with Remarkable Heterogeneity.

Advanced Science (Weinheim, Baden-Wurttemberg, Germany)

Wang, Xiaofang X; Chen, Yanjuan Y; Li, Zongcheng Z; Huang, Bingyan B; Xu, Ling L; Lai, Jing J; Lu, Yuhong Y; Zha, Xianfeng X; Liu, Bing B; Lan, Yu Y; Li, Yangqiu Y

Publication Date: 2021-10

Variant appearance in text: JAK2: R683G

PubMed Link: 34365737

Variant Present in the following documents:

• ADVS-8-2101447-s004.xlsx, sheet 1

View BVdb publication page

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Clinical application of whole transcriptome sequencing for the classification of patients with acute lymphoblastic leukemia.

Bmc Cancer

Walter, Wencke W; Shahswar, Rabia R; Stengel, Anna A; Meggendorfer, Manja M; Kern, Wolfgang W; Haferlach, Torsten T; Haferlach, Claudia C

Publication Date: 2021-08-02

Variant appearance in text: JAK2: 2047A>G

PubMed Link: 34340673

Variant Present in the following documents:

• 12885_2021_8635_MOESM9_ESM.xlsx, sheet 1

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Mutational profiling in acute lymphoblastic leukemia by RNA sequencing and chromosomal genomic array testing.

Cancer Medicine

Yeung, Cecilia C; Qu, Xiaoyu X; Sala-Torra, Olga O; Woolston, David D; Radich, Jerry J; Fang, Min M

Publication Date: 2021-08

Variant appearance in text: JAK2: 2047A>G; R683G

PubMed Link: 34288525

Variant Present in the following documents:

• Main text
• CAM4-10-5629.pdf

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Network Analysis Reveals Synergistic Genetic Dependencies for Rational Combination Therapy in Philadelphia Chromosome-Like Acute Lymphoblastic Leukemia.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Ding, Yang-Yang YY; Kim, Hannah H; Madden, Kellyn K; Loftus, Joseph P JP; Chen, Gregory M GM; Allen, David Hottman DH; Zhang, Ruitao R; Xu, Jason J; Chen, Chia-Hui CH; Hu, Yuxuan Y; Tasian, Sarah K SK; Tan, Kai K

Publication Date: 2021-09-15

Variant appearance in text: JAK2: R683G

PubMed Link: 34210682

Variant Present in the following documents:

• Main text
• 5109.pdf

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Network Analysis Reveals Synergistic Genetic Dependencies for Rational Combination Therapy in Philadelphia Chromosome-Like Acute Lymphoblastic Leukemia.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Ding, Yang-Yang YY; Kim, Hannah H; Madden, Kellyn K; Loftus, Joseph P JP; Chen, Gregory M GM; Allen, David Hottman DH; Zhang, Ruitao R; Xu, Jason J; Chen, Chia-Hui CH; Hu, Yuxuan Y; Tasian, Sarah K SK; Tan, Kai K

Publication Date: 2021-09-15

Variant appearance in text: JAK2: R683G

PubMed Link: 34210682

Variant Present in the following documents:

• Main text
• 5109.pdf

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Genomic Analyses of Pediatric Acute Lymphoblastic Leukemia Ph+ and Ph-Like-Recent Progress in Treatment.

International Journal Of Molecular Sciences

Kaczmarska, Agnieszka A; Śliwa, Patrycja P; Zawitkowska, Joanna J; Lejman, Monika M

Publication Date: 2021-06-15

Variant appearance in text: JAK2: R683G

PubMed Link: 34203891

Variant Present in the following documents:

• Main text

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Therapeutic potential of ruxolitinib and ponatinib in patients with EPOR-rearranged Philadelphia chromosome-like acute lymphoblastic leukemia.

Haematologica

Niswander, Lisa M LM; Loftus, Joseph P JP; Lainey, Élodie É; Caye-Eude, Aurélie A; Pondrom, Morgane M; Hottman, David A DA; Iacobucci, Ilaria I; Mullighan, Charles G CG; Jain, Nitin N; Konopleva, Marina M; Cavé, Hélène H; Baruchel, André A; Rohrlich, Pierre S PS; Tasian, Sarah K SK

Publication Date: 2021-10-01

Variant appearance in text: JAK2: R683G

PubMed Link: 34196168

Variant Present in the following documents:

• 1062763.pdf

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Functional Consequences of Mutations in Myeloproliferative Neoplasms.

Hemasphere

Constantinescu, Stefan N SN; Vainchenker, William W; Levy, Gabriel G; Papadopoulos, Nicolas N

Publication Date: 2021-06

Variant appearance in text: JAK2: R683G

PubMed Link: 34095761

Variant Present in the following documents:

• Main text
• hs9-5-e578.pdf

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Janus Kinases in Leukemia.

Cancers

Raivola, Juuli J; Haikarainen, Teemu T; Abraham, Bobin George BG; Silvennoinen, Olli O

Publication Date: 2021-02-14

Variant appearance in text: JAK2: R683G

PubMed Link: 33672930

Variant Present in the following documents:

• Main text
• cancers-13-00800.pdf

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The acquisition of molecular drivers in pediatric therapy-related myeloid neoplasms.

Nature Communications

Schwartz, Jason R JR; Ma, Jing J; Kamens, Jennifer J; Westover, Tamara T; Walsh, Michael P MP; Brady, Samuel W SW; Robert Michael, J J; Chen, Xiaolong X; Montefiori, Lindsey L; Song, Guangchun G; Wu, Gang G; Wu, Huiyun H; Branstetter, Cristyn C; Hiltenbrand, Ryan R; Walsh, Michael F MF; Nichols, Kim E KE; Maciaszek, Jamie L JL; Liu, Yanling Y; Kumar, Priyadarshini P; Easton, John J; Newman, Scott S; Rubnitz, Jeffrey E JE; Mullighan, Charles G CG; Pounds, Stanley S; Zhang, Jinghui J; Gruber, Tanja T; Ma, Xiaotu X; Klco, Jeffery M JM

Publication Date: 2021-02-12

Variant appearance in text: JAK2: R683G

PubMed Link: 33579957

Variant Present in the following documents:

• 41467_2021_21255_MOESM7_ESM.xlsx, sheet 1
• 41467_2021_21255_MOESM24_ESM.xlsx, sheet 1

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Integration of intra-sample contextual error modeling for improved detection of somatic mutations from deep sequencing.

Science Advances

Abelson, Sagi S; Zeng, Andy G X AGX; Nofech-Mozes, Ido I; Wang, Ting Ting TT; Ng, Stanley W K SWK; Minden, Mark D MD; Pugh, Trevor J TJ; Awadalla, Philip P; Shlush, Liran I LI; Murphy, Tracy T; Chan, Steven M SM; Dick, John E JE; Bratman, Scott V SV

Publication Date: 2020-12

Variant appearance in text: JAK2: R683G

PubMed Link: 33298453

Variant Present in the following documents:

• abe3722_Table_S3.xlsx, sheet 3

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Impact of Mutational Profile on the Management of Myeloproliferative Neoplasms: A Short Review of the Emerging Data.

Oncotargets And Therapy

Loscocco, Giuseppe G GG; Guglielmelli, Paola P; Vannucchi, Alessandro M AM

Publication Date: 2020

Variant appearance in text: JAK2: R683G

PubMed Link: 33293830

Variant Present in the following documents:

• Main text
• ott-13-12367.pdf

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