JAK2 c.2644_2645delinsGC ;(p.K882A)

Variant ID: 9-5089746-AA-GC

NM_004972.3(JAK2):c.2644_2645delinsGC;(p.K882A)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


14-3-3ζ inhibits heme oxygenase-1 (HO-1) degradation and promotes hepatocellular carcinoma proliferation: involvement of STAT3 signaling.

Journal Of Experimental & Clinical Cancer Research : Cr
Song, Jia J; Zhang, Xiaochao X; Liao, Zhibin Z; Liang, Huifang H; Chu, Liang L; Dong, Wei W; Zhang, Xuewu X; Ge, Qianyun Q; Liu, Qiumeng Q; Fan, Pan P; Zhang, Zhanguo Z; Zhang, Bixiang B
Publication Date: 2019-01-03

Variant appearance in text: JAK2: K882A
PubMed Link: 30606233
Variant Present in the following documents:
  • Main text
  • 13046_2018_Article_1007.pdf
View BVdb publication page



TRIM27 mediates STAT3 activation at retromer-positive structures to promote colitis and colitis-associated carcinogenesis.

Nature Communications
Zhang, Hong-Xia HX; Xu, Zhi-Sheng ZS; Lin, Hen H; Li, Mi M; Xia, Tian T; Cui, Kaisa K; Wang, Su-Yun SY; Li, Youjun Y; Shu, Hong-Bing HB; Wang, Yan-Yi YY
Publication Date: 2018-08-24

Variant appearance in text: JAK2: K882A
PubMed Link: 30143645
Variant Present in the following documents:
  • Main text
  • 41467_2018_Article_5796.pdf
View BVdb publication page



ATP binding to the pseudokinase domain of JAK2 is critical for pathogenic activation.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Hammarén, Henrik M HM; Ungureanu, Daniela D; Grisouard, Jean J; Skoda, Radek C RC; Hubbard, Stevan R SR; Silvennoinen, Olli O
Publication Date: 2015-04-14

Variant appearance in text: JAK2: K882A
PubMed Link: 25825724
Variant Present in the following documents:
  • Main text
View BVdb publication page