JAK2 c.2644_2646delinsGAC ;(p.K882D)

Variant ID: 9-5089746-AAA-GAC

NM_004972.3(JAK2):c.2644_2646delinsGAC;(p.K882D)

This variant was identified in 2 publications

View GRCh38 version.




Publications:


The pseudokinase domain of JAK2 is a dual-specificity protein kinase that negatively regulates cytokine signaling.

Nature Structural & Molecular Biology
Ungureanu, Daniela D; Wu, Jinhua J; Pekkala, Tuija T; Niranjan, Yashavanthi Y; Young, Clifford C; Jensen, Ole N ON; Xu, Chong-Feng CF; Neubert, Thomas A TA; Skoda, Radek C RC; Hubbard, Stevan R SR; Silvennoinen, Olli O
Publication Date: 2011-08-14

Variant appearance in text: JAK2: K882D
PubMed Link: 21841788
Variant Present in the following documents:
  • Main text
View BVdb publication page



Analysis of Jak2 catalytic function by peptide microarrays: the role of the JH2 domain and V617F mutation.

Plos One
Sanz, Arturo A; Ungureanu, Daniela D; Pekkala, Tuija T; Ruijtenbeek, Rob R; Touw, Ivo P IP; Hilhorst, Riet R; Silvennoinen, Olli O
Publication Date: 2011-04-18

Variant appearance in text: JAK2: K882D
PubMed Link: 21533163
Variant Present in the following documents:
  • Main text
  • pone.0018522.pdf
View BVdb publication page