Publications:

Stromal induction of BRD4 phosphorylation Results in Chromatin Remodeling and BET inhibitor Resistance in Colorectal Cancer.

Nature Communications

Wang, Wenyu W; Tang, Yen-An YA; Xiao, Qian Q; Lee, Wee Chyan WC; Cheng, Bing B; Niu, Zhitong Z; Oguz, Gokce G; Feng, Min M; Lee, Puay Leng PL; Li, Baojie B; Yang, Zi-Huan ZH; Chen, Yu-Feng YF; Lan, Ping P; Wu, Xiao-Jian XJ; Yu, Qiang Q

Publication Date: 2021-07-21

Variant appearance in text: JAK2: K882R

PubMed Link: 34290255

Variant Present in the following documents:

• Main text
• 41467_2021_24687_MOESM1_ESM.pdf
• 41467_2021_Article_24687.pdf

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Cbl-mediated K63-linked ubiquitination of JAK2 enhances JAK2 phosphorylation and signal transduction.

Scientific Reports

Liu, Chun-Shan CS; Yang-Yen, Hsin-Fang HF; Suen, Ching-Shu CS; Hwang, Ming-Jing MJ; Yen, Jeffrey Jong-Young JJ

Publication Date: 2017-07-04

Variant appearance in text: JAK2: K882R

PubMed Link: 28676638

Variant Present in the following documents:

• Main text
• 41598_2017_4078_MOESM1_ESM.pdf
• 41598_2017_Article_4078.pdf

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Mechanistic insights into activation and SOCS3-mediated inhibition of myeloproliferative neoplasm-associated JAK2 mutants from biochemical and structural analyses.

The Biochemical Journal

Varghese, Leila N LN; Ungureanu, Daniela D; Liau, Nicholas P D NP; Young, Samuel N SN; Laktyushin, Artem A; Hammaren, Henrik H; Lucet, Isabelle S IS; Nicola, Nicos A NA; Silvennoinen, Olli O; Babon, Jeffrey J JJ; Murphy, James M JM

Publication Date: 2014-03-01

Variant appearance in text: JAK2: K882R

PubMed Link: 24354892

Variant Present in the following documents:

• Main text

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Jak2 FERM domain interaction with the erythropoietin receptor regulates Jak2 kinase activity.

Molecular And Cellular Biology

Funakoshi-Tago, Megumi M; Pelletier, Stéphane S; Moritake, Hiroshi H; Parganas, Evan E; Ihle, James N JN

Publication Date: 2008-03

Variant appearance in text: JAK2: K882R

PubMed Link: 18160720

Variant Present in the following documents:

• Main text

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