JAK2 c.2738A>T ;(p.Y913F)

Variant ID: 9-5089840-A-T

NM_004972.3(JAK2):c.2738A>T;(p.Y913F)

This variant was identified in 2 publications

View GRCh38 version.




Publications:


Tyrosines 868, 966, and 972 in the kinase domain of JAK2 are autophosphorylated and required for maximal JAK2 kinase activity.

Molecular Endocrinology (Baltimore, Md.)
Argetsinger, Lawrence S LS; Stuckey, Jeanne A JA; Robertson, Scott A SA; Koleva, Rositsa I RI; Cline, Joel M JM; Marto, Jarrod A JA; Myers, Martin G MG; Carter-Su, Christin C
Publication Date: 2010-05

Variant appearance in text: JAK2: Y913F
PubMed Link: 20304997
Variant Present in the following documents:
  • Main text
View BVdb publication page



Jak2 FERM domain interaction with the erythropoietin receptor regulates Jak2 kinase activity.

Molecular And Cellular Biology
Funakoshi-Tago, Megumi M; Pelletier, Stéphane S; Moritake, Hiroshi H; Parganas, Evan E; Ihle, James N JN
Publication Date: 2008-03

Variant appearance in text: JAK2: Y913F
PubMed Link: 18160720
Variant Present in the following documents:
  • Main text
View BVdb publication page