Publications:

Acquired JAK2 mutations confer resistance to JAK inhibitors in cell models of acute lymphoblastic leukemia.

Npj Precision Oncology

Downes, Charlotte E J CEJ; McClure, Barbara J BJ; Bruning, John B JB; Page, Elyse E; Breen, James J; Rehn, Jacqueline J; Yeung, David T DT; White, Deborah L DL

Publication Date: 2021-08-10

Variant appearance in text: JAK2: E930G

PubMed Link: 34376782

Variant Present in the following documents:

• Main text
• 41698_2021_Article_215.pdf

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Targeting substrate-site in Jak2 kinase prevents emergence of genetic resistance.

Scientific Reports

Kesarwani, Meenu M; Huber, Erika E; Kincaid, Zachary Z; Evelyn, Chris R CR; Biesiada, Jacek J; Rance, Mark M; Thapa, Mahendra B MB; Shah, Neil P NP; Meller, Jarek J; Zheng, Yi Y; Azam, Mohammad M

Publication Date: 2015-09-30

Variant appearance in text: JAK2: E930G

PubMed Link: 26419724

Variant Present in the following documents:

• Main text
• srep14538.pdf

View BVdb publication page