Publications:

Immunogenomics of Colorectal Cancer Response to Checkpoint Blockade: Analysis of the KEYNOTE 177 Trial and Validation Cohorts.

Gastroenterology

Bortolomeazzi, Michele M; Keddar, Mohamed Reda MR; Montorsi, Lucia L; Acha-Sagredo, Amelia A; Benedetti, Lorena L; Temelkovski, Damjan D; Choi, Subin S; Petrov, Nedyalko N; Todd, Katrina K; Wai, Patty P; Kohl, Johannes J; Denner, Tamara T; Nye, Emma E; Goldstone, Robert R; Ward, Sophia S; Wilson, Gareth A GA; Al Bakir, Maise M; Swanton, Charles C; John, Susan S; Miles, James J; Larijani, Banafshe B; Kunene, Victoria V; Fontana, Elisa E; Arkenau, Hendrik-Tobias HT; Parker, Peter J PJ; Rodriguez-Justo, Manuel M; Shiu, Kai-Keen KK; Spencer, Jo J; Ciccarelli, Francesca D FD

Publication Date: 2021-10

Variant appearance in text: JAK2: Y934F

PubMed Link: 34197832

Variant Present in the following documents:

• mmc2.xlsx, sheet 3

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Tyrosines 868, 966, and 972 in the kinase domain of JAK2 are autophosphorylated and required for maximal JAK2 kinase activity.

Molecular Endocrinology (Baltimore, Md.)

Argetsinger, Lawrence S LS; Stuckey, Jeanne A JA; Robertson, Scott A SA; Koleva, Rositsa I RI; Cline, Joel M JM; Marto, Jarrod A JA; Myers, Martin G MG; Carter-Su, Christin C

Publication Date: 2010-05

Variant appearance in text: JAK2: Y934F

PubMed Link: 20304997

Variant Present in the following documents:

• Main text

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Jak2 FERM domain interaction with the erythropoietin receptor regulates Jak2 kinase activity.

Molecular And Cellular Biology

Funakoshi-Tago, Megumi M; Pelletier, Stéphane S; Moritake, Hiroshi H; Parganas, Evan E; Ihle, James N JN

Publication Date: 2008-03

Variant appearance in text: JAK2: Y934F

PubMed Link: 18160720

Variant Present in the following documents:

• Main text

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