Publications:

Molecular dissection of Janus kinases as drug targets for inflammatory diseases.

Frontiers In Immunology

Kwon, Sunghark S

Publication Date: 2022

Variant appearance in text: JAK2: L983F

PubMed Link: 36569926

Variant Present in the following documents:

• Main text
• fimmu-13-1075192.pdf

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Rational polypharmacological targeting of FLT3, JAK2, ABL, and ERK1 suppresses the adaptive resistance to FLT3 inhibitors in AML.

Blood Advances

Azhar, Mohammad M; Kincaid, Zachary Z; Kesarwani, Meenu M; Menke, Jacob J; Sweiterman, Joshua J; Ansari, Sekhu S; Reaves, Angela A; Ahmed, Arhama A; Shahzad, Rammsha R; Khan, Areeba A; Syed, Nuha N; Amir, Noor N; Wunderlich, Mark M; Latif, Tahir T; Seibel, William L WL; Azam, Mohammad M

Publication Date: 2022-08-31

Variant appearance in text: JAK2: L983F

PubMed Link: 36044389

Variant Present in the following documents:

• main.pdf

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Resistance Mechanisms in Pediatric B-Cell Acute Lymphoblastic Leukemia.

International Journal Of Molecular Sciences

Jędraszek, Krzysztof K; Malczewska, Marta M; Parysek-Wójcik, Karolina K; Lejman, Monika M

Publication Date: 2022-03-12

Variant appearance in text: JAK2: L983F

PubMed Link: 35328487

Variant Present in the following documents:

• Main text
• ijms-23-03067.pdf

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Acquired JAK2 mutations confer resistance to JAK inhibitors in cell models of acute lymphoblastic leukemia.

Npj Precision Oncology

Downes, Charlotte E J CEJ; McClure, Barbara J BJ; Bruning, John B JB; Page, Elyse E; Breen, James J; Rehn, Jacqueline J; Yeung, David T DT; White, Deborah L DL

Publication Date: 2021-08-10

Variant appearance in text: JAK2: L983F

PubMed Link: 34376782

Variant Present in the following documents:

• Main text
• 41698_2021_215_MOESM1_ESM.pdf
• 41698_2021_Article_215.pdf

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Targeting substrate-site in Jak2 kinase prevents emergence of genetic resistance.

Scientific Reports

Kesarwani, Meenu M; Huber, Erika E; Kincaid, Zachary Z; Evelyn, Chris R CR; Biesiada, Jacek J; Rance, Mark M; Thapa, Mahendra B MB; Shah, Neil P NP; Meller, Jarek J; Zheng, Yi Y; Azam, Mohammad M

Publication Date: 2015-09-30

Variant appearance in text: JAK2: L983F

PubMed Link: 26419724

Variant Present in the following documents:

• Main text
• srep14538.pdf

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