IRG and GBP host resistance factors target aberrant, "non-self" vacuoles characterized by the missing of "self" IRGM proteins.
Plos Pathogens
Haldar, Arun K AK; Saka, Hector A HA; Piro, Anthony S AS; Dunn, Joe Dan JD; Henry, Stanley C SC; Taylor, Gregory A GA; Frickel, Eva M EM; Valdivia, Raphael H RH; Coers, Jörn J