PMID: 16452151

A mutation in Tac1p, a transcription factor regulating CDR1 and CDR2, is coupled with loss of heterozygosity at chromosome 5 to mediate antifungal resistance in Candida albicans.

A Coste, V Turner, F Ischer, J Morschhäuser, A Forche, A Selmecki, J Berman, J Bille, D Sanglard

2 variants were identified in this publication

Variant ID Gene cDNA Protein Consequence Exon Intron
1-55521767-TG-AC PCSK9 c.901_902delTGinsAC p.Cys301Thr Missense 6/12 -
3-58107210-CT-TG FLNB c.3106_3107delCTinsTG p.Leu1036Trp Missense 20/46 -