PMID: 17804797

The self-inhibited structure of full-length PCSK9 at 1.9 A reveals structural homology with resistin within the C-terminal domain.

Proceedings of the National Academy of Sciences of the United States of America
EN Hampton, MW Knuth, J Li, JL Harris, SA Lesley, G Spraggon

4 variants were identified in this publication

Variant ID Gene cDNA Protein Consequence Exon Intron
1-55524222-C-T PCSK9 c.1405C>T p.Arg469Trp Missense 9/12 -
1-55525200-T-G PCSK9 c.1545T>G p.Phe515Leu Missense 10/12 -
1-55509689-T-A PCSK9 c.381T>A p.Ser127Arg Missense 2/12 -
1-55518422-C-T PCSK9 c.757C>T p.Leu253Phe Missense 5/12 -