PMID: 18193043

Newly identified loci that influence lipid concentrations and risk of coronary artery disease.

Nature genetics
CJ Willer, S Sanna, AU Jackson, A Scuteri, LL Bonnycastle, R Clarke, SC Heath, NJ Timpson, SS Najjar, HM Stringham, J Strait, WL Duren, A Maschio, F Busonero, A Mulas, G Albai, AJ Swift, MA Morken, N Narisu, D Bennett, S Parish, H Shen, P Galan, P Meneton, S Hercberg, D Zelenika, WM Chen, Y Li, LJ Scott, PA Scheet, J Sundvall, RM Watanabe, R Nagaraja, S Ebrahim, DA Lawlor, Y Ben-Shlomo, G Davey-Smith, AR Shuldiner, R Collins, RN Bergman, M Uda, J Tuomilehto, A Cao, FS Collins, E Lakatta, GM Lathrop, M Boehnke, D Schlessinger, KL Mohlke, GR Abecasis
2008-02

20 variants were identified in this publication


Variant ID Gene cDNA Protein Consequence Exon Intron
1-230294916-C-T GALNT2 c.127-19048C>T - IntronicSNV - 1/15
12-109895168-C-G KCTD10 c.527+267G>C - IntronicSNV - 5/6
9-107647220-C-T ABCA1 c.161-371G>A - IntronicSNV - 3/49
16-56919348-C-A SLC12A3 c.1925+72C>A - IntronicSNV - 15/25
16-56919348-C-G SLC12A3 c.1925+72C>G - IntronicSNV - 15/25
1-230295691-G-A GALNT2 c.127-18273G>A - IntronicSNV - 1/15
9-104362937-A-G GRIN3A c.2766+12721T>C - IntronicSNV - 6/8
1-63049593-C-T DOCK7 c.1801-668G>A - IntronicSNV - 15/48
9-107639414-G-A ABCA1 c.421+5906C>T - IntronicSNV - 5/49
16-68024995-G-A DPEP2 c.732+23C>T - IntronicSNV - 6/10
2-28076708-C-G RBKS c.222+4598G>C - IntronicSNV - 2/7
16-56997233-G-A CETP c.233+197G>A - IntronicSNV - 2/15
1-63049593-C-G DOCK7 c.1801-668G>C - IntronicSNV - 15/48
2-28076708-C-A RBKS c.222+4598G>T - IntronicSNV - 2/7
3-118948171-A-G B4GALT4 c.253+523T>C - IntronicSNV - 3/7
7-72982874-C-T TBL2 c.*1963G>A - IntergenicSNV 7/7 -
15-58727325-A-G LIPC c.88+3006A>G - IntronicSNV - 1/8
2-21232195-G-A APOB c.7545C>T p.Thr2515Thr Synonymous 26/29 -
19-19329924-C-T NCAN c.274C>T p.Pro92Ser Missense 3/15 -
11-116652207-C-T ZPR1 c.1179+667G>A - IntronicSNV - 12/13