PMID: 19443683

A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates.

Proceedings of the National Academy of Sciences of the United States of America
JC Chan, DE Piper, Q Cao, D Liu, C King, W Wang, J Tang, Q Liu, J Higbee, Z Xia, Y Di, S Shetterly, Z Arimura, H Salomonis, WG Romanow, ST Thibault, R Zhang, P Cao, XP Yang, T Yu, M Lu, MW Retter, G Kwon, K Henne, O Pan, MM Tsai, B Fuchslocher, E Yang, L Zhou, KJ Lee, M Daris, J Sheng, Y Wang, WD Shen, WC Yeh, M Emery, NP Walker, B Shan, M Schwarz, SM Jackson

1 variant was identified in this publication

Variant ID Gene cDNA Protein Consequence Exon Intron
1-55525252-AA-GC PCSK9 c.1597_1598delAAinsGC p.Asn533Ala Missense 10/12 -