PMID: 20959675

A PCSK9-binding antibody that structurally mimics the EGF(A) domain of LDL-receptor reduces LDL cholesterol in vivo.

Journal of lipid research
YG Ni, S Di Marco, JH Condra, LB Peterson, W Wang, F Wang, S Pandit, HA Hammond, R Rosa, RT Cummings, DD Wood, X Liu, MJ Bottomley, X Shen, RM Cubbon, SP Wang, DG Johns, C Volpari, L Hamuro, J Chin, L Huang, JZ Zhao, S Vitelli, P Haytko, D Wisniewski, LJ Mitnaul, CP Sparrow, B Hubbard, A CarfĂ­, A Sitlani
2011-01

2 variants were identified in this publication


Variant ID Gene cDNA Protein Consequence Exon Intron
1-55518374-C-T PCSK9 c.709C>T p.Arg237Trp Missense 5/12 -
1-55509689-T-A PCSK9 c.381T>A p.Ser127Arg Missense 2/12 -