PMID: 21818250

Genomic regions identified by overlapping clusters of nominally-positive SNPs from genome-wide studies of alcohol and illegal substance dependence.

PloS one
C Johnson, T Drgon, D Walther, GR Uhl
2011

258 variants were identified in this publication


Variant ID Gene cDNA Protein Consequence Exon Intron
5-96134235-G-A ERAP1 c.664-1223C>T - IntronicSNV - 3/19
6-125574509-T-C TPD52L1 c.300-354T>C - IntronicSNV - 4/6
11-122618891-A-G UBASH3B c.162-28036A>G - IntronicSNV - 1/13
6-129815171-A-C LAMA2 c.8244+1543A>C - IntronicSNV - 58/64
11-21592228-C-A NELL1 c.1981-82C>A - IntronicSNV - 17/19
3-7169453-A-C GRM7 c.520-18686A>C - IntronicSNV - 1/9
20-42654347-T-C TOX2 c.285+18915T>C - IntronicSNV - 3/8
6-31133894-G-C POU5F1 c.406-70C>G - IntronicSNV - 1/4
21-47982652-G-A DIP2A c.4089+934G>A - IntronicSNV - 34/37
2-213317071-C-A ERBB4 c.82+86102G>T - IntronicSNV - 1/26
6-12124855-G-A HIVEP1 c.4827G>A p.Met1609Ile Missense 4/9 -
15-100857655-C-T ADAMTS17 c.616+13439G>A - IntronicSNV - 3/21
2-213317071-C-T ERBB4 c.82+86102G>A - IntronicSNV - 1/26
3-21752050-G-C ZNF385D c.22+40337C>G - IntronicSNV - 1/7
5-167449057-T-A TENM2 c.1187-25375T>A - IntronicSNV - 6/29
13-100374060-A-C CLYBL c.63-51018A>C - IntronicSNV - 1/8
10-69114388-G-A CTNNA3 c.580-134760C>T - IntronicSNV - 5/17
15-101555292-C-T LRRK1 c.1533-239C>T - IntronicSNV - 11/33
8-17238653-G-C MTMR7 c.25-7904C>G - IntronicSNV - 1/13
8-17238653-G-T MTMR7 c.25-7904C>A - IntronicSNV - 1/13
2-166440547-A-C CSRNP3 c.1-11029A>C - IntronicSNV - 1/4
4-54967358-C-A GSX2 c.574+273C>A - IntronicSNV - 1/1
6-148790699-T-C SASH1 c.427+978T>C - IntronicSNV - 5/19
1-168665974-T-C DPT c.540-121A>G - IntronicSNV - 3/3
3-139784874-A-G CLSTN2 c.110-109919A>G - IntronicSNV - 1/16
16-80655883-T-G CDYL2 c.835-1051A>C - IntronicSNV - 3/6
6-31133894-G-A POU5F1 c.406-70C>T - IntronicSNV - 1/4
6-32180120-T-G NOTCH4 c.2680+131A>C - IntronicSNV - 17/29
9-129165060-T-G MVB12B c.662+7084T>G - IntronicSNV - 6/9
4-40503270-G-A RBM47 c.-155+14614C>T - intron_variant - 1/4
3-29421970-C-A RBMS3 c.76-54267C>A - IntronicSNV - 1/13
12-95521370-C-T FGD6 c.3082+7145G>A - IntronicSNV - 8/20
13-109472849-A-G MYO16 c.877+89A>G - IntronicSNV - 8/34
9-119795696-T-C ASTN2 c.1270+6402A>G - IntronicSNV - 5/21
21-41532330-A-G DSCAM c.3018+6815T>C - IntronicSNV - 16/32
11-21016033-A-G NELL1 c.1300+33927A>G - IntronicSNV - 12/19
18-55732192-T-C NEDD4L c.-316+17450T>C - intron_variant - 1/30
20-15807441-T-C MACROD2 c.646-35949T>C - IntronicSNV - 8/16
10-122346343-T-C PLPP4 c.617-2472T>C - IntronicSNV - 6/6
9-102846063-A-G ERP44 c.57+15003T>C - IntronicSNV - 1/11
5-78261957-A-G ARSB c.500-1528T>C - IntronicSNV - 2/7
8-4185750-T-C CSMD1 c.415+91725A>G - IntronicSNV - 3/69
1-169192110-T-C NME7 c.990+7846A>G - IntronicSNV - 10/11
8-4185750-T-A CSMD1 c.415+91725A>T - IntronicSNV - 3/69
7-1158144-A-T C7orf50 c.129+8749T>A - IntronicSNV - 2/4
7-1158144-A-G C7orf50 c.129+8749T>C - IntronicSNV - 2/4
1-201121523-T-A TMEM9 c.67-543A>T - IntronicSNV - 2/5
1-201121523-T-C TMEM9 c.67-543A>G - IntronicSNV - 2/5
18-57176916-G-A CCBE1 c.213-29446C>T - IntronicSNV - 2/10
10-127504389-G-A UROS c.147+357C>T - IntronicSNV - 3/9
4-5427691-G-A STK32B c.562+9030G>A - IntronicSNV - 6/11
5-7539712-A-G ADCY2 c.570+18700A>G - IntronicSNV - 3/24
21-41524631-T-C DSCAM c.3019-7973A>G - IntronicSNV - 16/32
1-246005798-C-A SMYD3 c.899+16000G>T - IntronicSNV - 10/11
13-95901825-A-T ABCC4 c.75-1818T>A - IntronicSNV - 1/30
1-233489054-T-G MAP3K21 c.987-499T>G - IntronicSNV - 2/9
8-4213293-A-G CSMD1 c.415+64182T>C - IntronicSNV - 3/69
10-127642276-A-G FANK1 c.14-26454A>G - IntronicSNV - 1/10
1-245557294-A-C KIF26B c.1000-25587A>C - IntronicSNV - 3/14
4-185323726-G-A IRF2 c.530-3493C>T - IntronicSNV - 6/8
3-14499020-C-T SLC6A6 c.608-438C>T - intron_variant - 5/14
16-84459557-T-C ATP2C2 c.986+150T>C - IntronicSNV - 11/26
16-84459557-T-A ATP2C2 c.986+150T>A - IntronicSNV - 11/26
3-14496162-G-A SLC6A6 c.608-3296G>A - intron_variant - 5/14
3-14496162-G-T SLC6A6 c.608-3296G>T - intron_variant - 5/14
8-3564197-C-A CSMD1 c.1009+1739G>T - IntronicSNV - 7/69
6-45879064-C-T CLIC5 c.1065+2901G>A - IntronicSNV - 5/5
13-103713089-G-A SLC10A2 c.378-2357C>T - IntronicSNV - 1/5
10-61937004-C-T ANK3 c.2185-4060G>A - IntronicSNV - 18/43
8-140982636-T-C TRAPPC9 c.3104+16298A>G - IntronicSNV - 19/22
2-240900121-C-T NDUFA10 c.*414G>A - 3-UTRSNV 10/10 -
21-27497497-G-A APP c.58-13034C>T - IntronicSNV - 1/17
12-72732514-G-A TRHDE c.1054-39261G>A - IntronicSNV - 2/18
7-50507678-C-T FIGNL1 c.*5283G>A - IntergenicSNV 4/4 -
8-139303835-T-A FAM135B c.157+19249A>T - IntronicSNV - 3/19
8-139303835-T-C FAM135B c.157+19249A>G - IntronicSNV - 3/19
1-183812807-G-A RGL1 c.244-3893G>A - IntronicSNV - 3/18
1-55546895-T-C USP24 c.7078+100A>G - IntronicSNV - 59/67
1-183812807-G-T RGL1 c.244-3893G>T - IntronicSNV - 3/18
8-102756851-A-G NCALD c.1-24994T>C - IntronicSNV - 5/7
8-102756851-A-C NCALD c.1-24994T>G - IntronicSNV - 5/7
10-90585138-T-C ANKRD22 c.399+657A>G - IntronicSNV - 4/5
12-66922606-C-T GRIP1 c.502+1005G>A - IntronicSNV - 5/22
20-42654347-T-A TOX2 c.285+18915T>A - IntronicSNV - 3/8
12-104894402-A-G CHST11 c.118+43095A>G - IntronicSNV - 1/2
6-129793717-C-A LAMA2 c.7301-642C>A - IntronicSNV - 51/64
4-147787745-T-A TTC29 c.885+905A>T - IntronicSNV - 8/12
11-122605909-A-G UBASH3B c.162-41018A>G - IntronicSNV - 1/13
22-45115579-A-G PRR5 c.188+5028A>G - IntronicSNV - 3/8
10-74840975-A-G P4HA1 c.1-6334T>C - IntronicSNV - 1/14
3-41490064-G-T ULK4 c.3492+6924C>A - IntronicSNV - 34/36
13-95893882-T-C ABCC4 c.306+5347A>G - IntronicSNV - 3/30
3-21752050-G-A ZNF385D c.22+40337C>T - IntronicSNV - 1/7
1-216796762-G-T ESRRG c.520+27553C>A - IntronicSNV - 4/7
4-187191787-G-A F11 c.56-976G>A - IntronicSNV - 2/14
10-90585347-A-T ANKRD22 c.399+448T>A - IntronicSNV - 4/5
10-90585347-A-G ANKRD22 c.399+448T>C - IntronicSNV - 4/5
14-80317460-G-A NRXN3 c.1079-10546G>A - IntronicSNV - 6/6
4-173760563-A-C GALNTL6 c.923+25689A>C - IntronicSNV - 7/12
1-55525400-G-A PCSK9 c.1681+64G>A - IntronicSNV - 10/11
12-81798657-G-A PPFIA2 c.762+909C>T - IntronicSNV - 7/30
12-6084191-G-T VWF c.7437+1086C>A - IntronicSNV - 43/51
12-6084191-G-C VWF c.7437+1086C>G - IntronicSNV - 43/51
5-16680772-C-T MYO10 c.4385-559G>A - IntronicSNV - 32/40
9-119766969-C-T ASTN2 c.1438+3402G>A - IntronicSNV - 6/21
9-119766969-C-A ASTN2 c.1438+3402G>T - IntronicSNV - 6/21
1-216796762-G-A ESRRG c.520+27553C>T - IntronicSNV - 4/7
12-72719792-A-C TRHDE c.1053+39058A>C - IntronicSNV - 2/18
11-92620160-A-T FAT3 c.12938-6A>T - IntronicSNV - 23/24
6-32170433-C-T NOTCH4 c.3232-57G>A - IntronicSNV - 20/29
20-49508683-G-A ADNP c.2568C>T p.Val856Val Synonymous 4/4 -
12-95384203-G-A NDUFA12 c.257+3743C>T - IntronicSNV - 3/3
22-23504959-C-T RAB36 c.*1208C>T - 3-UTRSNV 11/11 -
1-214589914-A-G PTPN14 c.345-1845T>C - IntronicSNV - 3/18
1-214589914-A-T PTPN14 c.345-1845T>A - IntronicSNV - 3/18
12-72719792-A-T TRHDE c.1053+39058A>T - IntronicSNV - 2/18
11-122634267-T-C UBASH3B c.162-12660T>C - IntronicSNV - 1/13
8-72195318-A-G EYA1 c.827-11186T>C - IntronicSNV - 9/17
3-41485477-T-C ULK4 c.3492+11511A>G - IntronicSNV - 34/36
3-41485477-T-A ULK4 c.3492+11511A>T - IntronicSNV - 34/36
7-29512086-C-T CHN2 c.577-7809C>T - IntronicSNV - 6/12
3-21762610-G-T ZNF385D c.22+29777C>A - IntronicSNV - 1/7
3-62661513-T-C CADPS c.889-13444A>G - IntronicSNV - 3/29
8-72195318-A-T EYA1 c.827-11186T>A - IntronicSNV - 9/17
21-41137256-G-A IGSF5 c.101-206G>A - IntronicSNV - 2/8
1-66039317-T-C LEPR c.494+1185T>C - IntronicSNV - 5/19
20-49489976-C-G BCAS4 c.490-2558C>G - IntronicSNV - 4/5
9-130309028-T-C FAM129B c.56-14971A>G - IntronicSNV - 1/13
18-57138957-T-C CCBE1 c.266-2118A>G - IntronicSNV - 3/10
8-3513337-T-C CSMD1 c.1010-39018A>G - IntronicSNV - 7/69
5-7538237-T-C ADCY2 c.570+17225T>C - IntronicSNV - 3/24
21-27513837-A-G APP c.57+29045T>C - IntronicSNV - 1/17
10-54031443-T-C PRKG1 c.1268+194T>C - IntronicSNV - 11/17
10-54031443-T-A PRKG1 c.1268+194T>A - IntronicSNV - 11/17
8-3513337-T-A CSMD1 c.1010-39018A>T - IntronicSNV - 7/69
13-109478592-A-G MYO16 c.1031+2966A>G - IntronicSNV - 9/34
3-37969439-T-C CTDSPL c.80-19109T>C - IntronicSNV - 1/6
5-107313403-A-C FBXL17 c.1822+43223T>G - IntronicSNV - 7/8
8-4213293-A-T CSMD1 c.415+64182T>A - IntronicSNV - 3/69
8-4213293-A-C CSMD1 c.415+64182T>G - IntronicSNV - 3/69
16-82936043-A-G CDH13 c.157+43965A>G - IntronicSNV - 2/13
10-115316812-T-C HABP2 c.69+3863T>C - IntronicSNV - 1/12
7-11554096-A-G THSD7A c.1822+26950T>C - IntronicSNV - 6/27
3-16408457-C-T RFTN1 c.1030+3126G>A - IntronicSNV - 6/9
8-97865490-G-A CPQ c.641+18082G>A - IntronicSNV - 3/7
8-3937595-A-G CSMD1 c.416-47974T>C - IntronicSNV - 3/69
14-57052897-G-A TMEM260 c.344+267G>A - IntronicSNV - 3/15
22-37408135-T-C TST c.596-769A>G - IntronicSNV - 2/2
1-28220484-C-A RPA2 c.728+39G>T - IntronicSNV - 8/8
4-147787745-T-C TTC29 c.885+905A>G - IntronicSNV - 8/12
11-20659757-G-A SLC6A5 c.1870-248G>A - IntronicSNV - 12/15
9-7165427-G-A KDM4C c.2901+70G>A - IntronicSNV - 20/21
9-7165427-G-C KDM4C c.2901+70G>C - IntronicSNV - 20/21
16-83232212-C-T CDH13 c.484-18738C>T - IntronicSNV - 4/13
16-82925549-G-C CDH13 c.157+33471G>C - IntronicSNV - 2/13
8-3053592-G-T CSMD1 c.5194+3644C>A - IntronicSNV - 33/69
10-115320498-C-T HABP2 c.70-6750C>T - IntronicSNV - 1/12
8-3053592-G-A CSMD1 c.5194+3644C>T - IntronicSNV - 33/69
5-107313403-A-G FBXL17 c.1822+43223T>C - IntronicSNV - 7/8
2-207953889-T-C KLF7 c.734-584A>G - IntronicSNV - 2/3
8-17229752-C-A MTMR7 c.147+875G>T - IntronicSNV - 2/13
15-89706770-A-C ABHD2 c.538+8005A>C - IntronicSNV - 9/14
20-20053676-T-C CFAP61 c.295-1270T>C - IntronicSNV - 3/26
1-183816683-G-T RGL1 c.244-17G>T - IntronicSNV - 3/18
8-139299165-C-T FAM135B c.158-21080G>A - IntronicSNV - 3/19
9-7150997-T-C KDM4C c.2782-14241T>C - IntronicSNV - 19/21
8-17181772-T-C MTMR7 c.865+6887A>G - IntronicSNV - 7/13
8-17181772-T-G MTMR7 c.865+6887A>C - IntronicSNV - 7/13
1-172360164-A-G DNM3 c.2522+2215A>G - IntronicSNV - 20/20
14-33228298-A-G AKAP6 c.3373-14586A>G - IntronicSNV - 11/13
14-33228298-A-T AKAP6 c.3373-14586A>T - IntronicSNV - 11/13
11-20669971-T-G SLC6A5 c.2070+1491T>G - IntronicSNV - 14/15
2-167177359-T-C SCN9A c.1-9093A>G - IntronicSNV - 1/26
8-3564181-A-C CSMD1 c.1009+1755T>G - IntronicSNV - 7/69
6-12117555-G-A HIVEP1 c.95-2568G>A - IntronicSNV - 3/8
6-148801719-C-T SASH1 c.627+6361C>T - IntronicSNV - 7/19
3-21762610-G-C ZNF385D c.22+29777C>G - IntronicSNV - 1/7
3-21762610-G-A ZNF385D c.22+29777C>T - IntronicSNV - 1/7
6-169022053-C-G SMOC2 c.907+13134C>G - IntronicSNV - 9/12
6-169022053-C-T SMOC2 c.907+13134C>T - IntronicSNV - 9/12
12-66944945-G-A GRIP1 c.137-9215C>T - IntronicSNV - 2/22
7-28848524-G-A CREB5 c.1006-280G>A - IntronicSNV - 8/10
1-162104658-T-C NOS1AP c.106-19537T>C - IntronicSNV - 1/9
10-74900783-C-T ECD c.1128-1288G>A - IntronicSNV - 9/13
1-28227665-T-C RPA2 c.334-3447A>G - IntronicSNV - 4/8
8-4217893-C-T CSMD1 c.415+59582G>A - IntronicSNV - 3/69
7-154652279-C-T DPP6 c.1714+6742C>T - intron_variant - 17/25
7-154652279-C-G DPP6 c.1714+6742C>G - intron_variant - 17/25
9-101829542-G-A COL15A1 c.3837+193G>A - IntronicSNV - 40/41
14-94941587-G-A SERPINA9 c.-18+886C>T - intron_variant - 1/4
21-40196388-C-T ETS2 c.*1575C>T - 3-UTRSNV 11/11 -
3-62663519-T-G CADPS c.889-15450A>C - IntronicSNV - 3/29
3-62663519-T-C CADPS c.889-15450A>G - IntronicSNV - 3/29
6-128833290-C-T PTPRK c.100+8114G>A - IntronicSNV - 1/30
6-169031488-C-T SMOC2 c.908-19873C>T - IntronicSNV - 9/12
3-62652520-A-G CADPS c.889-4451T>C - IntronicSNV - 3/29
15-33958127-A-G RYR3 c.5619+2189A>G - IntronicSNV - 36/103
16-53882657-C-T FTO c.895+4447C>T - IntronicSNV - 4/8
2-234923954-C-T TRPM8 c.*698C>T - IntronicSNV - 25/25
8-102754874-C-A NCALD c.1-23017G>T - IntronicSNV - 5/7
12-1997181-C-G CACNA2D4 c.782-946G>C - IntronicSNV - 6/37
12-1997181-C-T CACNA2D4 c.782-946G>A - IntronicSNV - 6/37
15-33958127-A-C RYR3 c.5619+2189A>C - IntronicSNV - 36/103
12-25245604-T-G LRMP c.606+2473T>G - IntronicSNV - 13/20
12-25245604-T-C LRMP c.606+2473T>C - IntronicSNV - 13/20
15-27183836-G-A GABRA5 c.725-1236G>A - IntronicSNV - 8/10
20-20059715-C-T CFAP61 c.566+3456C>T - IntronicSNV - 6/26
20-36989096-G-A LBP c.589-262G>A - IntronicSNV - 5/14
4-21324191-T-C KCNIP4 c.62-439859A>G - IntronicSNV - 1/8
15-27185306-C-T GABRA5 c.877+82C>T - IntronicSNV - 9/10
6-152738345-A-G SYNE1 c.5422-195T>C - IntronicSNV - 40/145
1-231363000-A-G C1orf131 c.511-186T>C - IntronicSNV - 3/6
1-20140581-C-T RNF186 c.*330G>A - 3-UTRSNV 1/1 -
8-3564181-A-T CSMD1 c.1009+1755T>A - IntronicSNV - 7/69
9-16212179-G-C C9orf92 c.254+3035C>G - IntronicSNV - 3/3
9-102846063-A-T ERP44 c.57+15003T>A - IntronicSNV - 1/11
16-82925549-G-A CDH13 c.157+33471G>A - IntronicSNV - 2/13
6-45924967-A-G CLIC5 c.541-1986T>C - IntronicSNV - 1/5
20-15902630-C-T MACROD2 c.776-11291C>T - IntronicSNV - 10/16
16-82925549-G-T CDH13 c.157+33471G>T - IntronicSNV - 2/13
6-129970962-C-T ARHGAP18 c.114-7799G>A - IntronicSNV - 1/14
1-214588601-G-A PTPN14 c.345-532C>T - IntronicSNV - 3/18
17-31789102-T-C ASIC2 c.556-350017A>G - IntronicSNV - 1/9
12-53039073-G-A KRT2 c.1650C>T p.Gly550Gly Synonymous 9/9 -
1-174805122-T-G RABGAP1L c.297+24024T>G - IntronicSNV - 2/8
1-162122627-A-G NOS1AP c.106-1568A>G - IntronicSNV - 1/9
12-111645043-A-G CUX2 c.64-6961A>G - IntronicSNV - 1/21
8-72184898-G-A EYA1 c.827-766C>T - IntronicSNV - 9/17
4-22441466-G-C ADGRA3 c.921-1423C>G - IntronicSNV - 7/18
4-22441466-G-T ADGRA3 c.921-1423C>A - IntronicSNV - 7/18
5-167435994-A-G TENM2 c.1186+15807A>G - IntronicSNV - 6/29
3-16408457-C-G RFTN1 c.1030+3126G>C - IntronicSNV - 6/9
21-41645484-A-C DSCAM c.2356+2540T>G - IntronicSNV - 11/32
2-240908234-G-A NDUFA10 c.1000-7631C>T - IntronicSNV - 9/9
1-162122627-A-T NOS1AP c.106-1568A>T - IntronicSNV - 1/9
3-16408778-C-T RFTN1 c.1030+2805G>A - IntronicSNV - 6/9
4-95558854-T-C PDLIM5 c.782-2573T>C - IntronicSNV - 8/12
11-88469243-A-T GRM5 c.912-82672T>A - IntronicSNV - 3/8
11-88452034-G-T GRM5 c.912-65463C>A - IntronicSNV - 3/8
16-54019686-G-A FTO c.1364+51665G>A - IntronicSNV - 8/8
19-52127134-C-G SIGLEC5 c.1464+2151G>C - IntronicSNV - 8/8
19-52127134-C-T SIGLEC5 c.1464+2151G>A - IntronicSNV - 8/8
3-10966588-A-G SLC6A11 c.1121-1102A>G - IntronicSNV - 8/13
8-140963979-C-T TRAPPC9 c.3104+34955G>A - IntronicSNV - 19/22
8-140963979-C-A TRAPPC9 c.3104+34955G>T - IntronicSNV - 19/22
3-134678040-C-T EPHB1 c.805+7146C>T - IntronicSNV - 3/15
8-4185750-T-G CSMD1 c.415+91725A>C - IntronicSNV - 3/69
4-178256913-C-A NEIL3 c.350C>A p.Pro117His Missense 3/10 -
4-178256913-C-G NEIL3 c.350C>G p.Pro117Arg Missense 3/10 -
4-178256913-C-T NEIL3 c.350C>T p.Pro117Leu Missense 3/10 -
14-73742281-G-A NUMB c.*1005C>T - 3-UTRSNV 13/13 -
20-51720422-T-C TSHZ2 c.40+130550T>C - IntronicSNV - 1/2
11-20669971-T-C SLC6A5 c.2070+1491T>C - IntronicSNV - 14/15
5-96134235-G-C ERAP1 c.664-1223C>G - IntronicSNV - 3/19
21-41596300-T-C DSCAM c.2357-35135A>G - IntronicSNV - 11/32
22-30855697-C-T SEC14L3 c.*311G>A - 3-UTRSNV 12/12 -
1-174805122-T-A RABGAP1L c.297+24024T>A - IntronicSNV - 2/8
1-168698173-C-T DPT c.240G>A p.Thr80Thr Synonymous 1/4 -