PMID: 22454423

Genetic variations and patient-reported quality of life among patients with lung cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology
JA Sloan, M de Andrade, P Decker, J Wampfler, C Oswold, M Clark, P Yang
2012-05-10

190 variants were identified in this publication


Variant ID Gene cDNA Protein Consequence Exon Intron
13-95752689-G-A ABCC4 c.2535+15487C>T - IntronicSNV - 20/30
5-80042275-T-G MSH3 c.1763+1841T>G - IntronicSNV - 12/23
5-131953510-A-G RAD50 c.3165-252A>G - IntronicSNV - 20/24
16-16181956-T-C ABCC1 c.2460+1108T>C - IntronicSNV - 18/30
13-95845631-T-A ABCC4 c.1263+1459A>T - IntronicSNV - 9/30
13-95845631-T-C ABCC4 c.1263+1459A>G - IntronicSNV - 9/30
10-131504495-T-C MGMT c.126-1664T>C - intron_variant - 2/4
12-1055452-A-G RAD52 c.-19+3316T>C - intron_variant - 1/11
20-33538999-G-C GSS c.129+528C>G - IntronicSNV - 2/12
13-95709072-T-C ABCC4 c.3367-3634A>G - IntronicSNV - 26/30
1-110201580-C-T GSTM4 c.457-42C>T - IntronicSNV - 6/7
13-95878842-G-A ABCC4 c.531+8022C>T - IntronicSNV - 4/30
1-110200360-T-C GSTM4 c.260-34T>C - IntronicSNV - 4/7
13-95726073-T-C ABCC4 c.2917+395A>G - IntronicSNV - 23/30
16-16205501-T-C ABCC1 c.3079+62T>C - IntronicSNV - 22/30
14-65409204-A-T CHURC1-FNTB c.6+18360A>T - IntronicSNV - 2/12
13-95791728-G-A ABCC4 c.2455+21715C>T - IntronicSNV - 19/30
10-101592622-A-G ABCC2 c.3258+734A>G - IntronicSNV - 23/31
6-52846902-T-C GSTA4 c.546+470A>G - IntronicSNV - 6/6
16-16052973-C-T ABCC1 c.48+9317C>T - IntronicSNV - 1/30
16-16052973-C-G ABCC1 c.48+9317C>G - IntronicSNV - 1/30
19-45862515-C-A ERCC2 c.1238-1558G>T - IntronicSNV - 12/22
10-131411620-T-C MGMT c.125+76979T>C - intron_variant - 2/4
13-95855500-T-C ABCC4 c.1161+3286A>G - IntronicSNV - 8/30
10-131319808-C-G MGMT c.-12-14697C>G - intron_variant - 1/4
2-48024876-C-T MSH6 c.628-874C>T - IntronicSNV - 3/9
3-9798140-C-G OGG1 c.748-15C>G - IntronicSNV - 4/6
13-95845272-G-A ABCC4 c.1263+1818C>T - IntronicSNV - 9/30
12-1022452-C-T RAD52 c.*105G>A - 3-UTRSNV 12/12 -
13-95880483-A-G ABCC4 c.531+6381T>C - IntronicSNV - 4/30
13-95785721-G-T ABCC4 c.2456-17466C>A - IntronicSNV - 19/30
10-131342129-A-C MGMT c.125+7488A>C - intron_variant - 2/4
13-95684700-T-C ABCC4 c.3870+2159A>G - IntronicSNV - 30/30
13-95893787-C-T ABCC4 c.306+5442G>A - IntronicSNV - 3/30
13-95893787-C-G ABCC4 c.306+5442G>C - IntronicSNV - 3/30
13-95893787-C-A ABCC4 c.306+5442G>T - IntronicSNV - 3/30
10-106037894-T-C GSTO2 c.366+20T>C - IntronicSNV - 4/6
16-16225971-G-A ABCC1 c.3966+179G>A - IntronicSNV - 27/30
13-95892356-A-G ABCC4 c.307-5268T>C - IntronicSNV - 3/30
13-95935589-T-C ABCC4 c.74+17906A>G - IntronicSNV - 1/30
6-28477895-T-C GPX6 c.241+633A>G - IntronicSNV - 2/4
15-40989021-T-C RAD51 c.-3+1398T>C - intron_variant - 1/9
10-131474474-G-A MGMT c.126-31685G>A - intron_variant - 2/4
6-52615415-T-G GSTA2 c.629A>C p.Glu210Ala Missense 7/7 -
10-131273707-C-T MGMT c.-13+8147C>T - intron_variant - 1/4
13-95823239-C-T ABCC4 c.1728-357G>A - IntronicSNV - 13/30
13-95823239-C-A ABCC4 c.1728-357G>T - IntronicSNV - 13/30
13-95843575-T-C ABCC4 c.1264-2779A>G - IntronicSNV - 9/30
10-131506190-C-T MGMT c.250C>T p.Leu84Phe Missense 3/5 -
10-131489782-A-G MGMT c.126-16377A>G - intron_variant - 2/4
10-131514470-C-T MGMT c.274+8163C>T - intron_variant - 3/4
9-100459578-T-G XPA c.1-4A>C - 5-UTRSNV 1/6 -
9-100459578-T-C XPA c.1-4A>G - 5-UTRSNV 1/6 -
13-95911900-A-G ABCC4 c.75-11893T>C - IntronicSNV - 1/30
16-16199255-A-G ABCC1 c.2736-1340A>G - IntronicSNV - 20/30
9-100448617-A-G XPA c.555+761T>C - IntronicSNV - 4/5
6-53376648-C-A GCLC c.639+2354G>T - IntronicSNV - 5/14
10-106033903-T-C GSTO2 c.1-771T>C - IntronicSNV - 1/6
16-16086666-C-G ABCC1 c.49-15007C>G - IntronicSNV - 1/30
6-53366989-C-T GCLC c.1282-1678G>A - IntronicSNV - 11/14
10-106025258-G-T GSTO1 c.466-584G>T - IntronicSNV - 4/5
13-95843434-G-T ABCC4 c.1264-2638C>A - IntronicSNV - 9/30
13-95719794-G-A ABCC4 c.3210+4122C>T - IntronicSNV - 25/30
13-95719794-G-C ABCC4 c.3210+4122C>G - IntronicSNV - 25/30
10-101558746-G-T ABCC2 c.868-218G>T - IntronicSNV - 7/31
2-48012846-C-T MSH6 c.260+2214C>T - IntronicSNV - 1/9
10-131489782-A-C MGMT c.126-16377A>C - intron_variant - 2/4
19-45856144-G-A ERCC2 c.1832-70C>T - IntronicSNV - 19/22
6-28499236-A-C GPX5 c.242-319A>C - IntronicSNV - 2/4
13-95719494-G-C ABCC4 c.3211-4381C>G - IntronicSNV - 25/30
3-14199887-G-A XPC c.1496C>T p.Ala499Val Missense 9/16 -
3-14195682-T-G XPC c.2034-1766A>C - IntronicSNV - 10/15
2-48025694-C-T MSH6 c.628-56C>T - IntronicSNV - 3/9
6-52766983-T-C GSTA3 c.272+161A>G - IntronicSNV - 4/6
13-95811599-A-G ABCC4 c.2455+1844T>C - IntronicSNV - 19/30
20-33542605-T-C GSS c.-9+925A>G - intron_variant - 1/12
13-95824103-T-C ABCC4 c.1728-1221A>G - IntronicSNV - 13/30
16-16089441-A-G ABCC1 c.49-12232A>G - IntronicSNV - 1/30
13-95673791-A-C ABCC4 c.*38T>G - 3-UTRSNV 31/31 -
19-45857235-C-T ERCC2 c.1666-643G>A - IntronicSNV - 17/22
19-45924362-G-C ERCC1 c.321+74C>G - IntronicSNV - 3/9
12-1031454-G-A RAD52 c.543+3162C>T - IntronicSNV - 7/11
2-48024402-T-C MSH6 c.627+1200T>C - IntronicSNV - 3/9
13-95942492-T-G ABCC4 c.74+11003A>C - IntronicSNV - 1/30
10-131365052-C-T MGMT c.125+30411C>T - intron_variant - 2/4
12-1050254-G-A RAD52 c.1-8030C>T - IntronicSNV - 1/11
3-14211101-A-C XPC c.412+837T>G - IntronicSNV - 3/15
3-14211101-A-G XPC c.412+837T>C - IntronicSNV - 3/15
16-16170477-G-T ABCC1 c.1988+219G>T - IntronicSNV - 15/30
10-101547042-C-T ABCC2 c.207+2504C>T - IntronicSNV - 2/31
13-95762005-A-G ABCC4 c.2535+6171T>C - IntronicSNV - 20/30
13-95784156-A-G ABCC4 c.2456-15901T>C - IntronicSNV - 19/30
1-94353449-G-T GCLM c.*1097C>A - 3-UTRSNV 7/7 -
1-94353449-G-A GCLM c.*1097C>T - 3-UTRSNV 7/7 -
10-131452917-C-T MGMT c.126-53242C>T - intron_variant - 2/4
10-131452917-C-G MGMT c.126-53242C>G - intron_variant - 2/4
1-110259016-G-T GSTM5 c.568-943G>T - IntronicSNV - 7/7
6-52708797-G-A GSTA5 c.-31+2057C>T - intron_variant - 1/6
6-53376091-T-C GCLC c.640-2043A>G - IntronicSNV - 5/14
6-53376091-T-A GCLC c.640-2043A>T - IntronicSNV - 5/14
2-47646968-C-T MSH2 c.1076+3400C>T - IntronicSNV - 6/15
19-45857235-C-G ERCC2 c.1666-643G>C - IntronicSNV - 17/22
6-52851979-A-G GSTA4 c.139+176T>C - IntronicSNV - 3/6
10-131559810-A-T MGMT c.414+2205A>T - intron_variant - 4/4
13-95691512-T-C ABCC4 c.3735+4424A>G - IntronicSNV - 29/30
10-131399616-G-T MGMT c.125+64975G>T - intron_variant - 2/4
10-131514391-T-C MGMT c.274+8084T>C - intron_variant - 3/4
9-100444951-C-G XPA c.673+2254G>C - IntronicSNV - 5/5
10-101605693-A-G ABCC2 c.4146+154A>G - IntronicSNV - 29/31
19-45871606-T-C ERCC2 c.360+282A>G - IntronicSNV - 5/22
13-95780019-T-C ABCC4 c.2456-11764A>G - IntronicSNV - 19/30
1-53069514-C-G GPX7 c.138+1295C>G - IntronicSNV - 1/2
1-53069514-C-T GPX7 c.138+1295C>T - IntronicSNV - 1/2
13-95822761-C-T ABCC4 c.1824+25G>A - IntronicSNV - 14/30
12-1058688-A-C RAD52 c.-19+80T>G - intron_variant - 1/11
13-95843434-G-A ABCC4 c.1264-2638C>T - IntronicSNV - 9/30
14-77796758-C-T GSTZ1 c.524+56C>T - IntronicSNV - 8/8
13-95757943-G-A ABCC4 c.2535+10233C>T - IntronicSNV - 20/30
13-95757943-G-C ABCC4 c.2535+10233C>G - IntronicSNV - 20/30
14-77792040-C-T GSTZ1 c.67+776C>T - IntronicSNV - 2/8
14-65408509-G-A CHURC1-FNTB c.6+17665G>A - IntronicSNV - 2/12
6-52703396-C-A GSTA5 c.88-989G>T - IntronicSNV - 2/6
6-52703396-C-T GSTA5 c.88-989G>A - IntronicSNV - 2/6
6-52703766-T-C GSTA5 c.88-1359A>G - IntronicSNV - 2/6
13-95849910-C-T ABCC4 c.1162-2719G>A - IntronicSNV - 8/30
6-52703766-T-G GSTA5 c.88-1359A>C - IntronicSNV - 2/6
8-30583904-C-T GSR c.306+1143G>A - IntronicSNV - 1/12
15-40987725-C-T RAD51 c.-3+102C>T - intron_variant - 1/9
10-131328646-T-C MGMT c.-12-5859T>C - intron_variant - 1/4
15-40987725-C-A RAD51 c.-3+102C>A - intron_variant - 1/9
5-131970885-T-G RAD50 c.3390-1922T>G - IntronicSNV - 21/24
10-101566010-C-T ABCC2 c.1530+806C>T - IntronicSNV - 11/31
5-80025471-G-A MSH3 c.1568+687G>A - IntronicSNV - 10/23
1-110201580-C-G GSTM4 c.457-42C>G - IntronicSNV - 6/7
16-16203345-C-T ABCC1 c.2872-1887C>T - IntronicSNV - 21/30
20-33529766-T-G GSS c.492-134A>C - IntronicSNV - 5/12
13-95903435-T-A ABCC4 c.75-3428A>T - IntronicSNV - 1/30
1-110260742-T-C GSTM5 c.*694T>C - 3-UTRSNV 8/8 -
5-80171134-A-T MSH3 c.3303-436A>T - IntronicSNV - 23/23
14-77794192-C-T GSTZ1 c.217-63C>T - IntronicSNV - 4/8
6-52617731-C-G GSTA2 c.335G>C p.Ser112Thr Missense 5/7 -
12-1024594-G-T RAD52 c.866-896C>A - IntronicSNV - 9/11
6-53401103-C-G GCLC c.150+8191G>C - IntronicSNV - 1/14
13-95707113-T-A ABCC4 c.3367-1675A>T - IntronicSNV - 26/30
13-95707113-T-C ABCC4 c.3367-1675A>G - IntronicSNV - 26/30
6-52765760-A-G GSTA3 c.273-887T>C - IntronicSNV - 4/6
16-16052973-C-A ABCC1 c.48+9317C>A - IntronicSNV - 1/30
10-101547042-C-G ABCC2 c.207+2504C>G - IntronicSNV - 2/31
10-131238239-C-G MGMT c.1-27241C>G - IntergenicSNV - 1/4
13-95918063-G-A ABCC4 c.75-18056C>T - IntronicSNV - 1/30
16-16155103-A-C ABCC1 c.1677+4951A>C - IntronicSNV - 12/30
19-45871606-T-A ERCC2 c.360+282A>T - IntronicSNV - 5/22
5-80168937-G-A MSH3 c.3133G>A p.Ala1045Thr Missense 23/24 -
11-4126009-T-G RRM1 c.109-1267T>G - IntronicSNV - 2/18
13-95933670-C-A ABCC4 c.74+19825G>T - IntronicSNV - 1/30
10-101594729-G-A ABCC2 c.3414+437G>A - IntronicSNV - 24/31
3-14195682-T-C XPC c.2034-1766A>G - IntronicSNV - 10/15
10-131238239-C-T MGMT c.1-27241C>T - IntergenicSNV - 1/4
13-95888671-T-C ABCC4 c.307-1583A>G - IntronicSNV - 3/30
16-16085236-C-T ABCC1 c.49-16437C>T - IntronicSNV - 1/30
6-52842781-T-C GSTA4 c.*487A>G - 3-UTRSNV 7/7 -
10-131449487-C-A MGMT c.126-56672C>A - intron_variant - 2/4
6-28499236-A-T GPX5 c.242-319A>T - IntronicSNV - 2/4
3-9788168-C-T BRPF1 c.3479+30C>T - IntronicSNV - 13/13
14-77790872-T-A GSTZ1 c.16-341T>A - IntronicSNV - 1/8
1-110198727-C-G GSTM4 c.1-285C>G - 5-UTRSNV 1/8 -
6-52843429-A-G GSTA4 c.547-39T>C - IntronicSNV - 6/6
19-44075636-G-A XRCC1 c.144+3426C>T - IntronicSNV - 2/16
10-131514862-A-G MGMT c.274+8555A>G - intron_variant - 3/4
1-94372878-T-C GCLM c.126+1716A>G - IntronicSNV - 1/6
1-53074532-C-A GPX7 c.*435C>A - 3-UTRSNV 3/3 -
16-16110955-G-T ABCC1 c.615+477G>T - IntronicSNV - 5/30
19-45857235-C-A ERCC2 c.1666-643G>T - IntronicSNV - 17/22
13-95820852-A-G ABCC4 c.1824+1934T>C - IntronicSNV - 14/30
5-80171134-A-C MSH3 c.3303-436A>C - IntronicSNV - 23/23
12-1022679-A-G RAD52 c.1196-61T>C - IntronicSNV - 11/11
6-53382370-G-C GCLC c.447-3075C>G - IntronicSNV - 3/14
5-79965536-A-G MSH3 c.580-380A>G - IntronicSNV - 3/23
5-80016874-T-C MSH3 c.1341-4398T>C - IntronicSNV - 8/23
2-48019485-T-C MSH6 c.457+1223T>C - IntronicSNV - 2/9
13-95951593-T-C ABCC4 c.74+1902A>G - IntronicSNV - 1/30
13-95903435-T-C ABCC4 c.75-3428A>G - IntronicSNV - 1/30
12-1052488-A-G RAD52 c.-19+6280T>C - intron_variant - 1/11
14-77792824-G-C GSTZ1 c.68-357G>C - IntronicSNV - 2/8
10-131449487-C-G MGMT c.126-56672C>G - intron_variant - 2/4
16-16108894-G-C ABCC1 c.489+409G>C - IntronicSNV - 4/30
16-16108894-G-A ABCC1 c.489+409G>A - IntronicSNV - 4/30
10-131449487-C-T MGMT c.126-56672C>T - intron_variant - 2/4
5-80171134-A-G MSH3 c.3303-436A>G - IntronicSNV - 23/23
20-33525407-G-A GSS c.609-581C>T - IntronicSNV - 6/12