PMID: 23900982

APOM and high-density lipoprotein cholesterol are associated with lung function and per cent emphysema.

The European respiratory journal
KM Burkart, A Manichaikul, JB Wilk, FS Ahmed, GL Burke, P Enright, NN Hansel, D Haynes, SR Heckbert, EA Hoffman, JD Kaufman, J Kurai, L Loehr, SJ London, Y Meng, GT O'Connor, E Oelsner, M Petrini, TD Pottinger, CA Powell, S Redline, JI Rotter, LJ Smith, M Soler Artigas, MD Tobin, MY Tsai, K Watson, W White, TR Young, SS Rich, RG Barr
2014-04

116 variants were identified in this publication


Variant ID Gene cDNA Protein Consequence Exon Intron
1-67800018-G-A IL12RB2 c.958+3525G>A - IntronicSNV - 7/15
8-31983424-G-T NRG1 c.38-469922G>T - IntronicSNV - 1/11
12-44428853-G-T TMEM117 c.410+90708G>T - IntronicSNV - 3/7
6-31916400-A-G CFB c.1036+111A>G - IntronicSNV - 7/17
17-16080849-A-G NCOR1 c.243-5540T>C - IntronicSNV - 3/45
17-16080849-A-T NCOR1 c.243-5540T>A - IntronicSNV - 3/45
6-32154998-C-T PBX2 c.1024+21G>A - IntronicSNV - 6/8
2-218674697-C-T TNS1 c.4810G>A p.Val1604Ile Missense 30/33 -
1-230221783-C-G GALNT2 c.126+18630C>G - IntronicSNV - 1/15
17-28538532-C-T SLC6A4 c.1205-90G>A - IntronicSNV - 9/14
3-190361217-G-T IL1RAP c.1052-820G>T - IntronicSNV - 8/10
1-55507314-G-A PCSK9 c.207+1597G>A - IntronicSNV - 1/11
9-128629537-G-A PBX3 c.50-48428G>A - IntronicSNV - 2/8
8-31970568-T-G NRG1 c.37+473621T>G - IntronicSNV - 1/11
19-36642874-T-G COX7A1 c.16-217A>C - IntronicSNV - 1/3
6-31783507-G-T HSPA1A c.1-27G>T - 5-UTRSNV 1/1 -
12-89741267-G-A DUSP6 c.*1764C>T - IntergenicSNV 3/3 -
12-89741267-G-T DUSP6 c.*1764C>A - IntergenicSNV 3/3 -
2-37094897-T-C STRN c.1547+60A>G - IntronicSNV - 12/17
3-127491509-T-G MGLL c.262+9123A>C - IntronicSNV - 3/7
3-127491509-T-C MGLL c.262+9123A>G - IntronicSNV - 3/7
4-103536670-A-T NFKB1 c.2750-921A>T - IntronicSNV - 23/23
3-25548555-T-C RARB c.448+5741T>C - IntronicSNV - 3/7
6-31472720-G-T MICB c.71-674G>T - IntronicSNV - 1/5
16-27358190-G-A IL4R c.513+251G>A - IntronicSNV - 6/10
17-6900076-G-A ALOX12 c.136-69G>A - IntronicSNV - 1/13
3-25529280-C-T RARB c.307-13393C>T - IntronicSNV - 2/7
6-35378124-G-A PPARD c.1-741G>A - IntronicSNV - 2/7
4-103536670-A-G NFKB1 c.2750-921A>G - IntronicSNV - 23/23
5-148206917-C-A ADRB2 c.523C>A p.Arg175Arg Synonymous 1/1 -
5-148206917-C-T ADRB2 c.523C>T p.Arg175Trp Missense 1/1 -
11-68567825-G-C CPT1A c.556-1002C>G - IntronicSNV - 5/18
6-32151934-A-G AGER c.52+14T>C - IntronicSNV - 1/10
14-65041483-A-G PPP1R36 c.668+176A>G - IntronicSNV - 8/11
7-55141476-G-A EGFR c.88+54418G>A - IntronicSNV - 1/27
8-32453358-G-A NRG1 c.50G>A p.Arg17Gln Missense 2/12 -
11-68567825-G-T CPT1A c.556-1002C>A - IntronicSNV - 5/18
1-55527918-C-T PCSK9 c.1863+689C>T - IntronicSNV - 11/11
12-53507213-G-A SOAT2 c.444-1961G>A - IntronicSNV - 5/14
6-31512720-G-C ATP6V1G2 c.*465C>G - 3-UTRSNV 3/3 -
2-136555659-T-C LCT c.4916A>G p.Asn1639Ser Missense 13/17 -
5-149189489-G-A PPARGC1B c.79-10507G>A - IntronicSNV - 1/11
6-35369491-A-G PPARD c.1-9374A>G - IntronicSNV - 2/7
6-136703304-C-T MAP7 c.637+1505G>A - IntronicSNV - 6/17
6-107665946-T-A PDSS2 c.297-10410A>T - IntronicSNV - 1/7
6-152422455-T-A ESR1 c.*2354T>A - 3-UTRSNV 8/8 -
3-30692451-C-T TGFBR2 c.529+499C>T - IntronicSNV - 4/7
3-49395757-G-A GPX1 c.1-46C>T - 5-UTRSNV 1/2 -
3-99483271-T-A COL8A1 c.-4+19406T>A - intron_variant - 3/4
6-107665946-T-C PDSS2 c.297-10410A>G - IntronicSNV - 1/7
6-32149816-T-C AGER c.964+208A>G - IntronicSNV - 8/10
6-32050067-T-G TNXB c.3482A>C p.His1161Pro Missense 9/44 -
9-119453455-C-T TRIM32 c.-82+3795C>T - intron_variant - 1/1
1-55527479-A-G PCSK9 c.1863+250A>G - IntronicSNV - 11/11
7-139676574-G-A TBXAS1 c.1134+14542G>A - intron_variant - 9/12
6-35378778-C-T PPARD c.1-87C>T - 5-UTRSNV 3/8 -
15-27116718-G-A GABRA5 c.86+2237G>A - IntronicSNV - 3/10
11-115341893-T-C CADM1 c.124+33096A>G - IntronicSNV - 1/9
3-38653277-A-C SCN5A c.704-1822T>G - IntronicSNV - 6/27
3-38653277-A-G SCN5A c.704-1822T>C - IntronicSNV - 6/27
1-55524601-G-C PCSK9 c.1503+281G>C - IntronicSNV - 9/11
5-52316172-C-T ITGA2 c.65-6406C>T - IntronicSNV - 1/29
3-38653277-A-T SCN5A c.704-1822T>A - IntronicSNV - 6/27
22-31209083-T-G OSBP2 c.854-57333T>G - IntronicSNV - 2/13
10-108836579-C-G SORCS1 c.558+87148G>C - IntronicSNV - 1/25
2-240025666-G-A HDAC4 c.2098-1074C>T - IntronicSNV - 15/26
6-31629499-A-G GPANK1 c.*544T>C - 3-UTRSNV 3/3 -
6-31777946-C-T HSPA1L c.1804G>A p.Glu602Lys Missense 2/2 -
12-25024151-G-A BCAT1 c.510+7313C>T - IntronicSNV - 5/10
6-31524851-C-T NFKBIL1 c.335-554C>T - IntronicSNV - 2/3
1-55524601-G-A PCSK9 c.1503+281G>A - IntronicSNV - 9/11
1-92312551-G-T TGFBR3 c.61+14477C>A - IntronicSNV - 2/16
9-98212608-C-T PTCH1 c.3450-386G>A - IntronicSNV - 20/23
15-99498412-G-C IGF1R c.3723-1878G>C - IntronicSNV - 20/20
5-52339114-T-C ITGA2 c.295+1063T>C - IntronicSNV - 3/29
3-170724390-G-A SLC2A2 c.613-496C>T - IntronicSNV - 5/10
17-53833551-G-A PCTP c.141+4946G>A - IntronicSNV - 1/5
1-53588752-G-A SLC1A7 c.216-8107C>T - IntronicSNV - 2/10
6-31917540-T-C CFB c.1408+206T>C - IntronicSNV - 10/17
6-32412592-G-C HLA-DRA c.*175G>C - 3_prime_UTR_variant 5/5 -
6-32412592-G-A HLA-DRA c.*175G>A - 3_prime_UTR_variant 5/5 -
10-108836579-C-T SORCS1 c.558+87148G>A - IntronicSNV - 1/25
6-31512720-G-T ATP6V1G2 c.*465C>A - 3-UTRSNV 3/3 -
6-32050067-T-C TNXB c.3482A>G p.His1161Arg Missense 9/44 -
6-32050067-T-A TNXB c.3482A>T p.His1161Leu Missense 9/44 -
3-30697889-A-G TGFBR2 c.529+5937A>G - IntronicSNV - 4/7
5-485929-T-C SLC9A3 c.676-583A>G - IntronicSNV - 3/16
7-139676574-G-C TBXAS1 c.1134+14542G>C - intron_variant - 9/12
6-31618121-A-T BAG6 c.109-717T>A - IntronicSNV - 2/24
6-31618121-A-C BAG6 c.109-717T>G - IntronicSNV - 2/24
6-31946614-G-A STK19 c.568-66G>A - IntronicSNV - 3/7
6-31940897-A-G STK19 c.567+363A>G - IntronicSNV - 3/7
1-55523361-A-G PCSK9 c.1180+174A>G - IntronicSNV - 7/11
1-55507314-G-T PCSK9 c.207+1597G>T - IntronicSNV - 1/11
2-218683154-A-G TNS1 c.3589T>C p.Trp1197Arg Missense 24/33 -
2-218683154-A-T TNS1 c.3589T>A p.Trp1197Arg Missense 24/33 -
16-27366126-A-G IL4R c.671-1003A>G - IntronicSNV - 7/10
6-31783507-G-C HSPA1A c.1-27G>C - 5-UTRSNV 1/1 -
3-119667289-G-A GSK3B c.283-1091C>T - IntronicSNV - 2/10
10-16880207-T-A CUBN c.10033-1826A>T - IntronicSNV - 62/66
8-100717494-G-A VPS13B c.6529+5334G>A - IntronicSNV - 36/61
17-43905481-T-G CRHR1 c.328-1100T>G - IntronicSNV - 4/13
1-156353970-A-G RHBG c.1028-348A>G - IntronicSNV - 9/11
22-31227901-T-C OSBP2 c.854-38515T>C - IntronicSNV - 2/13
2-218674697-C-G TNS1 c.4810G>C p.Val1604Leu Missense 30/33 -
1-218614743-G-A TGFB2 c.*39G>A - 3-UTRSNV 7/7 -
5-52289766-T-G ITGA2 c.64+4404T>G - IntronicSNV - 1/29
6-32628428-C-A HLA-DQB1 c.773-402G>T - IntronicSNV - 4/4
12-24990664-G-C BCAT1 c.818-1134C>G - IntronicSNV - 7/10
20-25195913-T-C ENTPD6 c.622+335T>C - IntronicSNV - 5/13
6-31783507-G-A HSPA1A c.1-27G>A - 5-UTRSNV 1/1 -
17-67501174-T-C MAP2K6 c.17-747T>C - IntronicSNV - 1/11
17-67501174-T-A MAP2K6 c.17-747T>A - IntronicSNV - 1/11
21-43699230-G-A ABCG1 c.621+2175G>A - IntronicSNV - 5/14
1-55524237-G-A PCSK9 c.1420G>A p.Val474Ile Missense 9/12 -
10-84514445-C-A NRG3 c.1027+16039C>A - IntronicSNV - 3/8