PMID: 27488001

N-acetyltransferase 2 (NAT2) gene polymorphism as a predisposing factor for phenytoin intoxication in tuberculous meningitis or tuberculoma patients having seizures - A pilot study.

The Indian journal of medical research
PS Adole, PS Kharbanda, S Sharma

9 variants were identified in this publication

Variant ID Gene cDNA Protein Consequence Exon Intron
3-197748392-TG-AC LMLN c.1441_1442delTGinsAC p.Cys481Thr Missense 13/16 -
8-18257795-C-T NAT2 c.282C>T p.Tyr94Tyr Synonymous 2/2 -
8-18257854-T-C NAT2 c.341T>C p.Ile114Thr Missense 2/2 -
8-18258370-G-A NAT2 c.857G>A p.Gly286Glu Missense 2/2 -
8-18258316-G-T NAT2 c.803G>T p.Arg268Ile Missense 2/2 -
8-18258316-G-A NAT2 c.803G>A p.Arg268Lys Missense 2/2 -
8-18257994-C-T NAT2 c.481C>T p.Leu161Leu Synonymous 2/2 -
3-197707219-G-C LMLN c.572G>C p.Gly191Ala Missense 6/16 -
8-18257704-G-A NAT2 c.191G>A p.Arg64Gln Missense 2/2 -