PMID: 28426714

A genetic risk score for CAD, psychological stress, and their interaction as predictors of CAD, fatal MI, non-fatal MI and cardiovascular death.

PloS one
T Svensson, M Kitlinski, G Engström, O Melander
2017

40 variants were identified in this publication


Variant ID Gene cDNA Protein Consequence Exon Intron
6-39174922-T-C KCNK5 c.187-11159A>G - IntronicSNV - 1/4
6-134213181-C-G TCF21 c.*241C>G - IntronicSNV 3/3 -
2-203745885-T-C WDR12 c.1195-225A>G - IntronicSNV - 12/12
2-44072576-G-C ABCG8 c.166-718G>C - IntronicSNV - 2/12
12-121435587-G-A HNF1A c.1501+119G>A - IntronicSNV - 7/9
12-121435587-G-T HNF1A c.1501+119G>T - IntronicSNV - 7/9
5-131667353-A-G SLC22A4 c.952-96A>G - IntronicSNV - 5/9
3-138122122-C-T MRAS c.*1011C>T - 3-UTRSNV 6/6 -
13-111049623-T-C COL4A2 c.181-27458T>C - IntronicSNV - 4/47
2-85767735-C-T MAT2A c.92-471C>T - IntronicSNV - 1/8
6-161143608-T-G PLG c.1256+9T>G - IntronicSNV - 10/18
6-161143608-T-C PLG c.1256+9T>C - IntronicSNV - 10/18
7-129663496-C-T ZC3HC1 c.1088G>A p.Arg363His Missense 8/10 -
7-129663496-C-A ZC3HC1 c.1088G>T p.Arg363Leu Missense 8/10 -
10-104719096-G-A CNNM2 c.1621+39238G>A - IntronicSNV - 1/7
13-28973621-G-A FLT1 c.1552-2416C>T - IntronicSNV - 11/29
1-222823529-A-C MIA3 c.3632-105A>C - IntronicSNV - 8/27
15-91416550-C-G FURIN c.1-2421C>G - IntronicSNV - 1/15
14-100133942-T-A HHIPL1 c.1649-617T>A - IntronicSNV - 6/8
17-2126504-G-C SMG6 c.145+13282C>G - IntronicSNV - 3/11
3-138122122-C-A MRAS c.*1011C>A - 3-UTRSNV 6/6 -
15-91416550-C-A FURIN c.1-2421C>A - IntronicSNV - 1/15
6-35034800-G-C ANKS1A c.2184+6770G>C - IntronicSNV - 13/23
10-91002927-C-T LIPA c.229+2506G>A - IntronicSNV - 3/9
2-44072576-G-T ABCG8 c.166-718G>T - IntronicSNV - 2/12
1-222823529-A-T MIA3 c.3632-105A>T - IntronicSNV - 8/27
1-222823529-A-G MIA3 c.3632-105A>G - IntronicSNV - 8/27
7-107244545-C-T BCAP29 c.589+3595C>T - IntronicSNV - 6/7
6-160863532-T-C SLC22A3 c.1289-261T>C - IntronicSNV - 7/10
15-79089111-A-G ADAMTS7 c.640T>C p.Ser214Pro Missense 4/24 -
14-100133942-T-C HHIPL1 c.1649-617T>C - IntronicSNV - 6/8
6-134213181-C-T TCF21 c.*241C>T - IntronicSNV 3/3 -
1-154422067-T-C IL6R c.997-320T>C - IntronicSNV - 7/9
1-56962821-A-G PLPP3 c.811-473T>C - IntronicSNV - 5/5
9-22003223-C-T CDKN2B c.*2763G>A - 3-UTRSNV 2/2 -
13-110960712-A-G COL4A2 c.99+242A>G - IntronicSNV - 3/47
19-11163601-G-T SMARCA4 c.4425-5330G>T - IntronicSNV - 30/34
6-160961137-T-C LPA c.5673A>G p.Ile1891Met Missense 36/39 -
6-12927544-C-G PHACTR1 c.251-126053C>G - IntronicSNV - 4/14
17-46991752-G-A UBE2Z c.578+1369G>A - IntronicSNV - 3/6