PMID: 29040597

Mendelian randomization: a novel approach for the prediction of adverse drug events and drug repurposing opportunities.

International journal of epidemiology
VM Walker, G Davey Smith, NM Davies, RM Martin
2017-12-01

42 variants were identified in this publication


Variant ID Gene cDNA Protein Consequence Exon Intron
12-112187840-A-G ACAD10 c.2817+691A>G - IntronicSNV - 18/20
4-68482401-T-C UBA6 c.*2314A>G - 3-UTRSNV 33/33 -
4-68520619-T-A UBA6 c.1105-5690A>T - IntronicSNV - 13/32
8-85714073-G-A RALYL c.372-2932G>A - IntronicSNV - 3/8
4-68489018-C-CC UBA6 c.2841-76_2841-76dup - IntronicInsertion - 30/32
12-112183574-T-C ACAD10 c.2116-374T>C - IntronicSNV - 13/20
1-46822372-A-AGAAG NSUN4 c.753+3672_753+3673insGAAG - IntronicInsertion - 4/5
4-68555508-T-A UBA6 c.134+6855A>T - IntronicSNV - 2/32
12-112379095-G-A TMEM116 c.39+1974C>T - IntronicSNV - 4/9
12-112403931-A-G TMEM116 c.1-22824T>C - IntronicSNV - 3/9
5-74648496-G-T HMGCR c.1368+1069G>T - IntronicSNV - 11/19
5-78373664-G-A BHMT2 c.166+229G>A - IntronicSNV - 2/7
4-68555508-T-C UBA6 c.134+6855A>G - IntronicSNV - 2/32
5-78373664-G-C BHMT2 c.166+229G>C - IntronicSNV - 2/7
1-46822998-T-C NSUN4 c.754-3378T>C - IntronicSNV - 4/5
17-61563661-C-G ACE c.2059-257C>G - IntronicSNV - 13/24
5-78367464-C-G BHMT2 c.33+1826C>G - IntronicSNV - 1/7
4-68560272-CACCCG-CACCCGCACCCG UBA6 c.134+2086_134+2091dup - IntronicInsertion - 2/32
12-112313216-A-T MAPKAPK5 c.579+4232A>T - IntronicSNV - 7/13
1-46864511-G-A FAAH c.196-3252G>A - IntronicSNV - 1/14
12-112151476-C-T ACAD10 c.850+1015C>T - IntronicSNV - 6/20
5-78295854-T-G DMGDH c.2386-1734A>C - IntronicSNV - 15/15
1-55522141-A-C PCSK9 c.996+279A>C - IntronicSNV - 6/11
7-44444568-A-G NUDCD3 c.643-386T>C - IntronicSNV - 3/5
4-68494237-AGCTCCAT-AGCTCCATAGCTCCAT UBA6 c.2400+545_2400+552dup - IntronicInsertion - 27/32
1-46822372-A-AG NSUN4 c.753+3672_753+3673insG - IntronicInsertion - 4/5
12-112141570-G-A ACAD10 c.336+1456G>A - IntronicSNV - 3/20
16-56999328-C-T CETP c.233+2292C>T - IntronicSNV - 2/15
1-55522141-A-G PCSK9 c.996+279A>G - IntronicSNV - 6/11
17-61560763-T-C ACE c.1488-58T>C - IntronicSNV - 9/24
12-112086099-T-C BRAP c.1415+1644A>G - IntronicSNV - 11/11
5-78566346-A-G JMY c.1033-7387A>G - IntronicSNV - 1/10
5-78361789-A-G DMGDH c.102-2179T>C - IntronicSNV - 1/15
17-61563661-C-T ACE c.2059-257C>T - IntronicSNV - 13/24
3-122003757-G-T CASR c.2956G>T p.Ala986Ser Missense 7/7 -
17-61563661-C-A ACE c.2059-257C>A - IntronicSNV - 13/24
5-78566346-A-T JMY c.1033-7387A>T - IntronicSNV - 1/10
2-113832333-C-A IL1F10 c.152C>A p.Ala51Asp Missense 4/5 -
5-78337225-G-A DMGDH c.1193+881C>T - IntronicSNV - 7/15
5-78367092-T-C BHMT2 c.33+1454T>C - IntronicSNV - 1/7
4-68520619-T-G UBA6 c.1105-5690A>C - IntronicSNV - 13/32
4-68494244-T-TAGCTC UBA6 c.2400+544_2400+545insGAGCT - IntronicInsertion - 27/32