PMID: 30287823

Germline pathogenic variants of 11 breast cancer genes in 7,051 Japanese patients and 11,241 controls.

Nature communications

Y Momozawa, Y Iwasaki, MT Parsons, Y Kamatani, A Takahashi, C Tamura, T Katagiri, T Yoshida, S Nakamura, K Sugano, Y Miki, M Hirata, K Matsuda, AB Spurdle, M Kubo

2018-10-04

1442 variants were identified in this publication

Variant ID	Gene	cDNA	Protein	Consequence	Exon	Intron
22-29092948-G-A	CHEK2	c.1165C>T	p.Arg389Cys	Missense	11/16	-
22-29092948-G-T	CHEK2	c.1165C>A	p.Arg389Ser	Missense	11/16	-
11-108153554-T-C	ATM	c.3694T>C	p.Ser1232Pro	Missense	25/63	-
13-32968954-C-G	BRCA2	c.9385C>G	p.Pro3129Ala	Missense	25/27	-
13-32968954-C-T	BRCA2	c.9385C>T	p.Pro3129Ser	Missense	25/27	-
13-32915264-G-A	BRCA2	c.6772G>A	p.Glu2258Lys	Missense	11/27	-
17-29652944-A-G	NF1	c.4879A>G	p.Thr1627Ala	Missense	36/57	-
16-68867274-G-A	CDH1	c.2521G>A	p.Glu841Lys	Missense	16/16	-
16-23632742-C-G	PALB2	c.3054G>C	p.Glu1018Asp	Missense	10/13	-
17-29657433-C-G	NF1	c.5666C>G	p.Ser1889Cys	Missense	38/57	-
13-32913457-C-G	BRCA2	c.4965C>G	p.Tyr1655*	Nonsense	11/27	-
13-32913457-C-A	BRCA2	c.4965C>A	p.Tyr1655*	Nonsense	11/27	-
19-1220703-G-A	STK11	c.721G>A	p.Ala241Thr	Missense	5/10	-
11-108115728-G-A	ATM	c.876G>A	p.Pro292Pro	Synonymous	7/63	-
17-29588752-G-A	NF1	c.4538G>A	p.Arg1513Gln	Missense	34/57	-
16-23634405-G-T	PALB2	c.2881C>A	p.Leu961Met	Missense	9/13	-
16-23634405-G-A	PALB2	c.2881C>T	p.Leu961Leu	Synonymous	9/13	-
16-23641346-G-A	PALB2	c.2129C>T	p.Thr710Met	Missense	5/13	-
17-41245262-T-A	BRCA1	c.2286A>T	p.Arg762Ser	Missense	10/23	-
17-41245262-T-C	BRCA1	c.2286A>G	p.Arg762Arg	Synonymous	10/23	-
13-32920978-C-G	BRCA2	c.6952C>G	p.Arg2318Gly	Missense	13/27	-
13-32920978-C-T	BRCA2	c.6952C>T	p.Arg2318*	Nonsense	13/27	-
17-29546036-A-G	NF1	c.1541A>G	p.Gln514Arg	Missense	14/57	-
11-108142115-C-T	ATM	c.3059C>T	p.Thr1020Ile	Missense	20/63	-
17-41251834-G-A	BRCA1	c.505C>T	p.Gln169*	Nonsense	7/23	-
16-23632742-C-A	PALB2	c.3054G>T	p.Glu1018Asp	Missense	10/13	-
13-32929041-G-T	BRCA2	c.7051G>T	p.Ala2351Ser	Missense	14/27	-
19-1220703-G-T	STK11	c.721G>T	p.Ala241Ser	Missense	5/10	-
17-29557285-C-T	NF1	c.2998C>T	p.Arg1000Cys	Missense	23/57	-
16-23647133-G-A	PALB2	c.734C>T	p.Ala245Val	Missense	4/13	-
13-32929041-G-A	BRCA2	c.7051G>A	p.Ala2351Thr	Missense	14/27	-
13-32929041-G-C	BRCA2	c.7051G>C	p.Ala2351Pro	Missense	14/27	-
11-108164152-G-A	ATM	c.4724G>A	p.Arg1575His	Missense	31/63	-
17-41223165-C-T	BRCA1	c.4766G>A	p.Arg1589His	Missense	15/23	-
17-7578522-T-A	TP53	c.408A>T	p.Gln136His	Missense	5/11	-
16-23632772-G-A	PALB2	c.3024C>T	p.Pro1008Pro	Synonymous	10/13	-
16-23632772-G-C	PALB2	c.3024C>G	p.Pro1008Pro	Synonymous	10/13	-
19-1223107-C-T	STK11	c.1044C>T	p.Asp348Asp	Synonymous	8/10	-
19-1221961-C-T	STK11	c.876C>T	p.Tyr292Tyr	Synonymous	7/10	-
13-32913870-A-T	BRCA2	c.5378A>T	p.Asn1793Ile	Missense	11/27	-
16-23619228-C-T	PALB2	c.3307G>A	p.Val1103Met	Missense	12/13	-
16-23619228-C-G	PALB2	c.3307G>C	p.Val1103Leu	Missense	12/13	-
17-41223202-A-G	BRCA1	c.4729T>C	p.Ser1577Pro	Missense	15/23	-
19-1207008-C-T	STK11	c.96C>T	p.Thr32Thr	Synonymous	1/10	-
13-32937504-C-A	BRCA2	c.8165C>A	p.Thr2722Lys	Missense	18/27	-
11-108115589-A-G	ATM	c.737A>G	p.Asn246Ser	Missense	7/63	-
16-23619284-G-A	PALB2	c.3251C>T	p.Ser1084Leu	Missense	12/13	-
17-29657473-G-T	NF1	c.5706G>T	p.Thr1902Thr	Synonymous	38/57	-
11-108143485-A-T	ATM	c.3190A>T	p.Met1064Leu	Missense	22/63	-
11-108143485-A-G	ATM	c.3190A>G	p.Met1064Val	Missense	22/63	-
17-41244007-C-T	BRCA1	c.3541G>A	p.Val1181Ile	Missense	10/23	-
19-1207008-C-G	STK11	c.96C>G	p.Thr32Thr	Synonymous	1/10	-
16-68862090-G-A	CDH1	c.2178G>A	p.Leu726Leu	Synonymous	14/16	-
17-7578437-G-A	TP53	c.493C>T	p.Gln165*	Nonsense	5/11	-
13-32914175-G-C	BRCA2	c.5683G>C	p.Glu1895Gln	Missense	11/27	-
16-68842610-A-C	CDH1	c.546A>C	p.Lys182Asn	Missense	5/16	-
17-7579886-G-A	TP53	c.27C>T	p.Ser9Ser	Synonymous	2/11	-
17-7579886-G-C	TP53	c.27C>G	p.Ser9Arg	Missense	2/11	-
16-23641778-C-T	PALB2	c.1697G>A	p.Arg566His	Missense	5/13	-
16-23649398-C-A	PALB2	c.101G>T	p.Arg34Leu	Missense	2/13	-
13-32913966-C-T	BRCA2	c.5474C>T	p.Ala1825Val	Missense	11/27	-
17-29587401-T-C	NF1	c.4382T>C	p.Ile1461Thr	Missense	33/57	-
17-29553485-G-A	NF1	c.2034G>A	p.Pro678Pro	Synonymous	18/57	-
17-29553485-G-C	NF1	c.2034G>C	p.Pro678Pro	Synonymous	18/57	-
13-32913070-A-G	BRCA2	c.4578A>G	p.Thr1526Thr	Synonymous	11/27	-
11-108196240-C-G	ATM	c.6776C>G	p.Ser2259Cys	Missense	46/63	-
13-32900706-G-C	BRCA2	c.587G>C	p.Ser196Thr	Missense	7/27	-
17-29587459-C-T	NF1	c.4440C>T	p.Asp1480Asp	Synonymous	33/57	-
11-108236132-G-A	ATM	c.9068G>A	p.Gly3023Asp	Missense	63/63	-
11-108137926-G-C	ATM	c.2495G>C	p.Arg832Pro	Missense	17/63	-
11-108137926-G-A	ATM	c.2495G>A	p.Arg832His	Missense	17/63	-
11-108124595-A-G	ATM	c.1953A>G	p.Leu651Leu	Synonymous	13/63	-
17-29653162-G-T	NF1	c.5097G>T	p.Glu1699Asp	Missense	36/57	-
16-23647133-G-C	PALB2	c.734C>G	p.Ala245Gly	Missense	4/13	-
19-1226627-C-G	STK11	c.1283C>G	p.Ser428Trp	Missense	9/10	-
11-108173622-G-A	ATM	c.5362G>A	p.Gly1788Ser	Missense	36/63	-
16-23646813-C-G	PALB2	c.1054G>C	p.Glu352Gln	Missense	4/13	-
13-32968840-G-A	BRCA2	c.9271G>A	p.Val3091Ile	Missense	25/27	-
22-29090043-C-T	CHEK2	c.1567G>A	p.Ala523Thr	Missense	14/16	-
11-108137934-G-T	ATM	c.2503G>T	p.Val835Leu	Missense	17/63	-
16-68845758-G-A	CDH1	c.1004G>A	p.Arg335Gln	Missense	7/16	-
17-29560213-G-A	NF1	c.3690G>A	p.Val1230Val	Synonymous	27/57	-
19-1222991-C-T	STK11	c.928C>T	p.Arg310Trp	Missense	8/10	-
17-41267763-C-A	BRCA1	c.114G>T	p.Lys38Asn	Missense	3/23	-
17-41245669-C-T	BRCA1	c.1879G>A	p.Val627Ile	Missense	10/23	-
17-29654819-C-A	NF1	c.5508C>A	p.Ile1836Ile	Synonymous	37/57	-
17-29654819-C-T	NF1	c.5508C>T	p.Ile1836Ile	Synonymous	37/57	-
19-1207063-A-C	STK11	c.151A>C	p.Met51Leu	Missense	1/10	-
11-108163375-G-T	ATM	c.4466G>T	p.Arg1489Leu	Missense	30/63	-
11-108163375-G-A	ATM	c.4466G>A	p.Arg1489His	Missense	30/63	-
16-23641218-G-A	PALB2	c.2257C>T	p.Arg753*	Nonsense	5/13	-
16-23641218-G-T	PALB2	c.2257C>A	p.Arg753Arg	Synonymous	5/13	-
17-29560213-G-T	NF1	c.3690G>T	p.Val1230Val	Synonymous	27/57	-
13-32912008-G-T	BRCA2	c.3516G>T	p.Ser1172Ser	Synonymous	11/27	-
11-108155144-G-C	ATM	c.3937G>C	p.Glu1313Gln	Missense	26/63	-
22-29085174-A-G	CHEK2	c.1620T>C	p.Asp540Asp	Synonymous	15/16	-
17-29546043-C-G	NF1	c.1548C>G	p.Pro516Pro	Synonymous	14/57	-
13-32911748-A-G	BRCA2	c.3256A>G	p.Ile1086Val	Missense	11/27	-
16-68846049-G-A	CDH1	c.1020G>A	p.Thr340Thr	Synonymous	8/16	-
16-68846049-G-T	CDH1	c.1020G>T	p.Thr340Thr	Synonymous	8/16	-
17-29546043-C-T	NF1	c.1548C>T	p.Pro516Pro	Synonymous	14/57	-
11-108206576-G-T	ATM	c.8156G>T	p.Arg2719Leu	Missense	56/63	-
13-32929011-C-G	BRCA2	c.7021C>G	p.Arg2341Gly	Missense	14/27	-
16-68847301-C-G	CDH1	c.1223C>G	p.Ala408Gly	Missense	9/16	-
16-68847301-C-T	CDH1	c.1223C>T	p.Ala408Val	Missense	9/16	-
10-89690828-G-T	PTEN	c.235G>T	p.Ala79Ser	Missense	4/9	-
10-89690828-G-A	PTEN	c.235G>A	p.Ala79Thr	Missense	4/9	-
16-68862193-G-A	CDH1	c.2281G>A	p.Gly761Arg	Missense	14/16	-
16-23649273-G-C	PALB2	c.109C>G	p.Arg37Gly	Missense	3/13	-
13-32906422-A-G	BRCA2	c.807A>G	p.Thr269Thr	Synonymous	10/27	-
13-32906422-A-T	BRCA2	c.807A>T	p.Thr269Thr	Synonymous	10/27	-
11-108150266-T-G	ATM	c.3333T>G	p.Leu1111Leu	Synonymous	23/63	-
11-108124759-C-T	ATM	c.2117C>T	p.Ser706Leu	Missense	13/63	-
22-29126425-C-T	CHEK2	c.431G>A	p.Arg144Gln	Missense	3/16	-
13-32912806-C-T	BRCA2	c.4314C>T	p.Val1438Val	Synonymous	11/27	-
22-29092948-G-C	CHEK2	c.1165C>G	p.Arg389Gly	Missense	11/16	-
19-1226628-G-C	STK11	c.1284G>C	p.Ser428Ser	Synonymous	9/10	-
19-1226628-G-A	STK11	c.1284G>A	p.Ser428Ser	Synonymous	9/10	-
17-7578540-G-T	TP53	c.390C>A	p.Leu130Leu	Synonymous	5/11	-
13-32911295-G-T	BRCA2	c.2803G>T	p.Asp935Tyr	Missense	11/27	-
13-32911295-G-C	BRCA2	c.2803G>C	p.Asp935His	Missense	11/27	-
11-108098388-C-T	ATM	c.37C>T	p.Arg13Cys	Missense	2/63	-
11-108216597-G-A	ATM	c.8546G>A	p.Arg2849Gln	Missense	58/63	-
11-108216597-G-C	ATM	c.8546G>C	p.Arg2849Pro	Missense	58/63	-
11-108175456-C-G	ATM	c.5551C>G	p.Leu1851Val	Missense	37/63	-
17-29654671-C-A	NF1	c.5360C>A	p.Thr1787Lys	Missense	37/57	-
13-32913346-T-A	BRCA2	c.4854T>A	p.Asp1618Glu	Missense	11/27	-
17-29585493-C-T	NF1	c.4242C>T	p.Ile1414Ile	Synonymous	31/57	-
22-29130495-T-C	CHEK2	c.215A>G	p.Tyr72Cys	Missense	2/16	-
22-29130495-T-G	CHEK2	c.215A>C	p.Tyr72Ser	Missense	2/16	-
13-32907428-A-AA	BRCA2	c.1813dupA	p.Ile605Asnfs*11	Frameshift	10/27	-
11-108158434-C-T	ATM	c.4101C>T	p.Asp1367Asp	Synonymous	27/63	-
19-1220599-C-T	STK11	c.617C>T	p.Ala206Val	Missense	5/10	-
11-108180917-T-G	ATM	c.5793T>G	p.Ala1931Ala	Synonymous	39/63	-
19-1220599-C-G	STK11	c.617C>G	p.Ala206Gly	Missense	5/10	-
13-32954213-C-T	BRCA2	c.9187C>T	p.Pro3063Ser	Missense	24/27	-
17-7577108-C-T	TP53	c.830G>A	p.Cys277Tyr	Missense	8/11	-
13-32914915-T-G	BRCA2	c.6423T>G	p.Gly2141Gly	Synonymous	11/27	-
16-68849575-T-C	CDH1	c.1478T>C	p.Val493Ala	Missense	10/16	-
13-32914046-G-T	BRCA2	c.5554G>T	p.Val1852Phe	Missense	11/27	-
11-108170516-C-T	ATM	c.5081C>T	p.Ala1694Val	Missense	34/63	-
17-29559110-A-G	NF1	c.3217A>G	p.Met1073Val	Missense	25/57	-
13-32914632-A-G	BRCA2	c.6140A>G	p.Tyr2047Cys	Missense	11/27	-
16-23619203-G-A	PALB2	c.3332C>T	p.Pro1111Leu	Missense	12/13	-
17-41244665-G-A	BRCA1	c.2883C>T	p.Asn961Asn	Synonymous	10/23	-
13-32911042-A-G	BRCA2	c.2550A>G	p.Gln850Gln	Synonymous	11/27	-
13-32945234-G-A	BRCA2	c.8629G>A	p.Glu2877Lys	Missense	20/27	-
13-32945234-G-T	BRCA2	c.8629G>T	p.Glu2877*	Nonsense	20/27	-
17-7577108-C-A	TP53	c.830G>T	p.Cys277Phe	Missense	8/11	-
19-1223125-C-T	STK11	c.1062C>T	p.Phe354Phe	Synonymous	8/10	-
19-1223125-C-G	STK11	c.1062C>G	p.Phe354Leu	Missense	8/10	-
16-68849575-T-G	CDH1	c.1478T>G	p.Val493Gly	Missense	10/16	-
16-23646194-A-G	PALB2	c.1673T>C	p.Ile558Thr	Missense	4/13	-
13-32914046-G-C	BRCA2	c.5554G>C	p.Val1852Leu	Missense	11/27	-
13-32914046-G-A	BRCA2	c.5554G>A	p.Val1852Ile	Missense	11/27	-
13-32900694-T-C	BRCA2	c.575T>C	p.Met192Thr	Missense	7/27	-
17-29661953-A-G	NF1	c.5847A>G	p.Arg1949Arg	Synonymous	39/57	-
11-108170516-C-G	ATM	c.5081C>G	p.Ala1694Gly	Missense	34/63	-
22-29121016-G-A	CHEK2	c.670C>T	p.Arg224Cys	Missense	5/16	-
22-29121016-G-C	CHEK2	c.670C>G	p.Arg224Gly	Missense	5/16	-
13-32914995-G-C	BRCA2	c.6503G>C	p.Gly2168Ala	Missense	11/27	-
13-32914995-G-A	BRCA2	c.6503G>A	p.Gly2168Glu	Missense	11/27	-
11-108202221-A-G	ATM	c.7566A>G	p.Gln2522Gln	Synonymous	51/63	-
17-7577091-G-T	TP53	c.847C>A	p.Arg283Ser	Missense	8/11	-
17-7577091-G-A	TP53	c.847C>T	p.Arg283Cys	Missense	8/11	-
13-32907504-C-T	BRCA2	c.1889C>T	p.Thr630Ile	Missense	10/27	-
22-29091225-C-G	CHEK2	c.1394G>C	p.Ser465Thr	Missense	13/16	-
11-108119802-C-T	ATM	c.1208C>T	p.Ser403Leu	Missense	9/63	-
17-41267762-A-T	BRCA1	c.115T>A	p.Cys39Ser	Missense	3/23	-
17-41267762-A-G	BRCA1	c.115T>C	p.Cys39Arg	Missense	3/23	-
11-108129764-A-G	ATM	c.2428A>G	p.Lys810Glu	Missense	16/63	-
17-41267762-A-C	BRCA1	c.115T>G	p.Cys39Gly	Missense	3/23	-
17-41197729-T-C	BRCA1	c.5558A>G	p.Tyr1853Cys	Missense	23/23	-
17-41242960-C-A	BRCA1	c.4185+1G>T	-	IntronicSNV	-	11/22
13-32910982-C-A	BRCA2	c.2490C>A	p.Asn830Lys	Missense	11/27	-
17-41242960-C-T	BRCA1	c.4185+1G>A	-	IntronicSNV	-	11/22
13-32910982-C-T	BRCA2	c.2490C>T	p.Asn830Asn	Synonymous	11/27	-
13-32910982-C-G	BRCA2	c.2490C>G	p.Asn830Lys	Missense	11/27	-
11-108126944-T-C	ATM	c.2127T>C	p.Ile709Ile	Synonymous	14/63	-
13-32912306-A-G	BRCA2	c.3814A>G	p.Met1272Val	Missense	11/27	-
17-29654606-G-A	NF1	c.5295G>A	p.Ser1765Ser	Synonymous	37/57	-
16-23641409-G-T	PALB2	c.2066C>A	p.Ser689*	Nonsense	5/13	-
17-29657473-G-A	NF1	c.5706G>A	p.Thr1902Thr	Synonymous	38/57	-
13-32914606-T-C	BRCA2	c.6114T>C	p.His2038His	Synonymous	11/27	-
10-89711873-A-G	PTEN	c.493-2A>G	-	IntronicSNV	-	5/8
16-68856080-C-G	CDH1	c.1888C>G	p.Leu630Val	Missense	12/16	-
16-23641130-G-A	PALB2	c.2345C>T	p.Pro782Leu	Missense	5/13	-
11-108186750-T-C	ATM	c.6108T>C	p.Tyr2036Tyr	Synonymous	42/63	-
16-23641130-G-T	PALB2	c.2345C>A	p.Pro782Gln	Missense	5/13	-
13-32972356-A-G	BRCA2	c.9706A>G	p.Lys3236Glu	Missense	27/27	-
13-32929146-T-TT	BRCA2	c.7156_7156dup	p.Ser2386Phefs*6	Frameshift	14/27	-
17-7579885-C-T	TP53	c.28G>A	p.Val10Ile	Missense	2/11	-
13-32911593-T-G	BRCA2	c.3101T>G	p.Ile1034Ser	Missense	11/27	-
17-41244007-C-G	BRCA1	c.3541G>C	p.Val1181Leu	Missense	10/23	-
13-32912785-A-G	BRCA2	c.4293A>G	p.Ala1431Ala	Synonymous	11/27	-
17-41246156-G-A	BRCA1	c.1392C>T	p.Thr464Thr	Synonymous	10/23	-
13-32971139-G-A	BRCA2	c.9606G>A	p.Pro3202Pro	Synonymous	26/27	-
16-23646654-G-C	PALB2	c.1213C>G	p.Pro405Ala	Missense	4/13	-
19-1226574-C-T	STK11	c.1230C>T	p.Ala410Ala	Synonymous	9/10	-
17-29676201-C-T	NF1	c.7190C>T	p.Thr2397Ile	Missense	48/57	-
17-7579885-C-G	TP53	c.28G>C	p.Val10Leu	Missense	2/11	-
17-29661994-A-G	NF1	c.5888A>G	p.Asn1963Ser	Missense	39/57	-
17-29654784-C-T	NF1	c.5473C>T	p.Arg1825Trp	Missense	37/57	-
11-108168053-A-G	ATM	c.4949A>G	p.Asn1650Ser	Missense	33/63	-
17-41246156-G-C	BRCA1	c.1392C>G	p.Thr464Thr	Synonymous	10/23	-
17-41234470-A-G	BRCA1	c.4308T>C	p.Ser1436Ser	Synonymous	12/23	-
17-41244643-T-C	BRCA1	c.2905A>G	p.Asn969Asp	Missense	10/23	-
17-29684013-C-A	NF1	c.7711C>A	p.His2571Asn	Missense	52/57	-
16-68845757-C-T	CDH1	c.1003C>T	p.Arg335*	Nonsense	7/16	-
17-29490284-C-G	NF1	c.369C>G	p.Thr123Thr	Synonymous	4/57	-
11-108203586-ATATTA-A	ATM	c.7886_7890delTATTA	p.Ile2629Serfs*25	Frameshift	53/63	-
13-32954030-A-AA	BRCA2	c.9097_9097dupA	p.Thr3033Asnfs*11	Frameshift	23/27	-
11-108155106-A-G	ATM	c.3899A>G	p.Tyr1300Cys	Missense	26/63	-
13-32914229-T-G	BRCA2	c.5737T>G	p.Cys1913Gly	Missense	11/27	-
19-1226570-G-A	STK11	c.1226G>A	p.Arg409Gln	Missense	9/10	-
13-32931967-G-A	BRCA2	c.7706G>A	p.Gly2569Asp	Missense	16/27	-
19-1220590-C-G	STK11	c.608C>G	p.Pro203Arg	Missense	5/10	-
13-32930636-G-A	BRCA2	c.7507G>A	p.Val2503Ile	Missense	15/27	-
19-1226574-C-G	STK11	c.1230C>G	p.Ala410Ala	Synonymous	9/10	-
13-32912919-A-G	BRCA2	c.4427A>G	p.Asp1476Gly	Missense	11/27	-
11-108186763-A-G	ATM	c.6121A>G	p.Met2041Val	Missense	42/63	-
11-108206649-G-A	ATM	c.8229G>A	p.Thr2743Thr	Synonymous	56/63	-
13-32914068-ATTAAA-A	BRCA2	c.5576_5580delTTAAA	p.Ile1859Lysfs*12	Frameshift	11/27	-
17-29665111-G-A	NF1	c.6710G>A	p.Arg2237Gln	Missense	44/57	-
13-32911954-C-T	BRCA2	c.3462C>T	p.Thr1154Thr	Synonymous	11/27	-
17-41203094-G-A	BRCA1	c.5318C>T	p.Thr1773Ile	Missense	20/23	-
13-32954009-C-G	BRCA2	c.9076C>G	p.Gln3026Glu	Missense	23/27	-
19-1220708-G-T	STK11	c.726G>T	p.Gly242Gly	Synonymous	5/10	-
17-29657457-A-G	NF1	c.5690A>G	p.Asn1897Ser	Missense	38/57	-
17-41209101-G-T	BRCA1	c.5245C>A	p.Pro1749Thr	Missense	19/23	-
16-68867342-C-A	CDH1	c.2589C>A	p.Asn863Lys	Missense	16/16	-
13-32950837-G-C	BRCA2	c.8663G>C	p.Arg2888Pro	Missense	21/27	-
13-32950837-G-A	BRCA2	c.8663G>A	p.Arg2888His	Missense	21/27	-
13-32950837-G-T	BRCA2	c.8663G>T	p.Arg2888Leu	Missense	21/27	-
19-1219347-G-A	STK11	c.399G>A	p.Val133Val	Synonymous	3/10	-
13-32906558-T-A	BRCA2	c.943T>A	p.Cys315Ser	Missense	10/27	-
13-32931893-C-T	BRCA2	c.7632C>T	p.Gly2544Gly	Synonymous	16/27	-
16-68847240-G-A	CDH1	c.1162G>A	p.Glu388Lys	Missense	9/16	-
11-108143537-A-G	ATM	c.3242A>G	p.Asn1081Ser	Missense	22/63	-
13-32893253-C-T	BRCA2	c.107C>T	p.Ser36Phe	Missense	3/27	-
13-32914152-C-G	BRCA2	c.5660C>G	p.Thr1887Arg	Missense	11/27	-
11-108151824-G-A	ATM	c.3505G>A	p.Glu1169Lys	Missense	24/63	-
11-108205805-C-G	ATM	c.8120C>G	p.Ser2707Cys	Missense	55/63	-
16-68842610-A-G	CDH1	c.546A>G	p.Lys182Lys	Synonymous	5/16	-
17-7578437-G-T	TP53	c.493C>A	p.Gln165Lys	Missense	5/11	-
13-32912733-C-T	BRCA2	c.4241C>T	p.Thr1414Met	Missense	11/27	-
13-32914175-G-A	BRCA2	c.5683G>A	p.Glu1895Lys	Missense	11/27	-
17-41209101-G-C	BRCA1	c.5245C>G	p.Pro1749Ala	Missense	19/23	-
16-23646327-C-T	PALB2	c.1540G>A	p.Gly514Arg	Missense	4/13	-
17-41226379-C-T	BRCA1	c.4644G>A	p.Thr1548Thr	Synonymous	14/23	-
17-41258497-A-G	BRCA1	c.188T>C	p.Leu63Ser	Missense	4/23	-
17-41258497-A-T	BRCA1	c.188T>A	p.Leu63*	Nonsense	4/23	-
17-41219631-T-G	BRCA1	c.5068A>C	p.Lys1690Gln	Missense	16/23	-
11-108206685-T-G	ATM	c.8265T>G	p.Tyr2755*	Nonsense	56/63	-
17-41226540-T-G	BRCA1	c.4485-2A>C	-	IntronicSNV	-	13/22
16-23641778-C-G	PALB2	c.1697G>C	p.Arg566Pro	Missense	5/13	-
17-29654538-G-A	NF1	c.5227G>A	p.Val1743Ile	Missense	37/57	-
17-41244822-T-A	BRCA1	c.2726A>T	p.Asn909Ile	Missense	10/23	-
17-29654538-G-T	NF1	c.5227G>T	p.Val1743Leu	Missense	37/57	-
17-29556080-G-C	NF1	c.2447G>C	p.Arg816Pro	Missense	21/57	-
17-41246791-C-T	BRCA1	c.757G>A	p.Ala253Thr	Missense	10/23	-
17-41228567-A-G	BRCA1	c.4422T>C	p.Ala1474Ala	Synonymous	13/23	-
13-32913692-G-T	BRCA2	c.5200G>T	p.Glu1734*	Nonsense	11/27	-
17-41219701-G-T	BRCA1	c.4998C>A	p.Tyr1666*	Nonsense	16/23	-
11-108168035-T-C	ATM	c.4931T>C	p.Met1644Thr	Missense	33/63	-
17-41243800-C-T	BRCA1	c.3748G>A	p.Glu1250Lys	Missense	10/23	-
16-23647372-G-A	PALB2	c.495C>T	p.Gly165Gly	Synonymous	4/13	-
13-32944567-G-A	BRCA2	c.8360G>A	p.Arg2787His	Missense	19/27	-
13-32913692-G-C	BRCA2	c.5200G>C	p.Glu1734Gln	Missense	11/27	-
13-32913692-G-A	BRCA2	c.5200G>A	p.Glu1734Lys	Missense	11/27	-
17-29541475-A-T	NF1	c.1399A>T	p.Thr467Ser	Missense	13/57	-
17-41243800-C-A	BRCA1	c.3748G>T	p.Glu1250*	Nonsense	10/23	-
16-23649399-G-A	PALB2	c.100C>T	p.Arg34Cys	Missense	2/13	-
17-41256153-C-T	BRCA1	c.427G>A	p.Glu143Lys	Missense	6/23	-
13-32913070-A-C	BRCA2	c.4578A>C	p.Thr1526Thr	Synonymous	11/27	-
11-108203619-C-G	ATM	c.7919C>G	p.Thr2640Ser	Missense	53/63	-
17-29556080-G-A	NF1	c.2447G>A	p.Arg816Gln	Missense	21/57	-
13-32914593-G-A	BRCA2	c.6101G>A	p.Arg2034His	Missense	11/27	-
17-29557278-G-T	NF1	c.2991G>T	p.Arg997Ser	Missense	23/57	-
17-29508476-C-T	NF1	c.623C>T	p.Ala208Val	Missense	6/57	-
13-32914897-ACTTAA-A	BRCA2	c.6405_6409delCTTAA	p.Asn2135Lysfs*3	Frameshift	11/27	-
17-7574012-C-G	TP53	c.1015G>C	p.Glu339Gln	Missense	10/11	-
17-7574012-C-A	TP53	c.1015G>T	p.Glu339*	Nonsense	10/11	-
17-7574012-C-T	TP53	c.1015G>A	p.Glu339Lys	Missense	10/11	-
11-108180917-T-C	ATM	c.5793T>C	p.Ala1931Ala	Synonymous	39/63	-
17-29550541-C-T	NF1	c.1801C>T	p.Arg601Trp	Missense	16/57	-
17-41246081-C-T	BRCA1	c.1467G>A	p.Glu489Glu	Synonymous	10/23	-
11-108151833-G-T	ATM	c.3514G>T	p.Ala1172Ser	Missense	24/63	-
17-29653162-G-C	NF1	c.5097G>C	p.Glu1699Asp	Missense	36/57	-
11-108124682-C-T	ATM	c.2040C>T	p.Phe680Phe	Synonymous	13/63	-
11-108115564-A-G	ATM	c.712A>G	p.Ile238Val	Missense	7/63	-
11-108123629-G-C	ATM	c.1888G>C	p.Val630Leu	Missense	12/63	-
19-1220590-C-T	STK11	c.608C>T	p.Pro203Leu	Missense	5/10	-
11-108175529-G-A	ATM	c.5624G>A	p.Arg1875Gln	Missense	37/63	-
17-29670074-C-T	NF1	c.7047C>T	p.His2349His	Synonymous	47/57	-
16-23646329-G-T	PALB2	c.1538C>A	p.Thr513Lys	Missense	4/13	-
16-23646329-G-A	PALB2	c.1538C>T	p.Thr513Ile	Missense	4/13	-
17-41244617-T-G	BRCA1	c.2931A>C	p.Pro977Pro	Synonymous	10/23	-
17-29585518-A-G	NF1	c.4267A>G	p.Lys1423Glu	Missense	31/57	-
17-29585518-A-C	NF1	c.4267A>C	p.Lys1423Gln	Missense	31/57	-
13-32914461-A-G	BRCA2	c.5969A>G	p.Asp1990Gly	Missense	11/27	-
17-41256251-T-G	BRCA1	c.329A>C	p.Lys110Thr	Missense	6/23	-
17-29496991-G-A	NF1	c.562G>A	p.Ala188Thr	Missense	5/57	-
11-108175529-G-C	ATM	c.5624G>C	p.Arg1875Pro	Missense	37/63	-
17-41244265-T-C	BRCA1	c.3283A>G	p.Lys1095Glu	Missense	10/23	-
17-29559872-G-A	NF1	c.3469G>A	p.Val1157Ile	Missense	26/57	-
11-108158382-C-T	ATM	c.4049C>T	p.Thr1350Met	Missense	27/63	-
13-32910842-A-G	BRCA2	c.2350A>G	p.Met784Val	Missense	11/27	-
13-32912610-T-C	BRCA2	c.4118T>C	p.Met1373Thr	Missense	11/27	-
17-29576098-C-T	NF1	c.4071C>T	p.Phe1357Phe	Synonymous	30/57	-
13-32911319-A-G	BRCA2	c.2827A>G	p.Ile943Val	Missense	11/27	-
11-108121656-G-A	ATM	c.1464G>A	p.Trp488*	Nonsense	10/63	-
11-108121656-G-T	ATM	c.1464G>T	p.Trp488Cys	Missense	10/63	-
16-23614916-TAAGT-T	PALB2	c.3426_3429delACTT	p.Leu1142Phefs*20	Frameshift	13/13	-
13-32900251-C-T	BRCA2	c.439C>T	p.Gln147*	Nonsense	5/27	-
13-32914464-C-T	BRCA2	c.5972C>T	p.Ala1991Val	Missense	11/27	-
17-7578183-C-T	TP53	c.666G>A	p.Pro222Pro	Synonymous	6/11	-
16-23646375-C-A	PALB2	c.1492G>T	p.Asp498Tyr	Missense	4/13	-
17-7578183-C-A	TP53	c.666G>T	p.Pro222Pro	Synonymous	6/11	-
16-23646375-C-T	PALB2	c.1492G>A	p.Asp498Asn	Missense	4/13	-
17-29557287-T-C	NF1	c.3000T>C	p.Arg1000Arg	Synonymous	23/57	-
13-32903579-G-T	BRCA2	c.632-1G>T	-	IntronicSNV	-	7/26
13-32913026-C-T	BRCA2	c.4534C>T	p.Arg1512Cys	Missense	11/27	-
13-32913026-C-A	BRCA2	c.4534C>A	p.Arg1512Ser	Missense	11/27	-
17-41244435-T-G	BRCA1	c.3113A>C	p.Glu1038Ala	Missense	10/23	-
11-108201135-A-G	ATM	c.7502A>G	p.Asn2501Ser	Missense	50/63	-
16-68867396-C-T	CDH1	c.2643C>T	p.Asp881Asp	Synonymous	16/16	-
22-29121265-C-T	CHEK2	c.539G>A	p.Arg180Gln	Missense	4/16	-
17-41243696-G-T	BRCA1	c.3852C>A	p.His1284Gln	Missense	10/23	-
16-23640966-C-A	PALB2	c.2509G>T	p.Glu837*	Nonsense	5/13	-
16-68847375-G-A	CDH1	c.1297G>A	p.Asp433Asn	Missense	9/16	-
13-32912299-T-G	BRCA2	c.3807T>G	p.Val1269Val	Synonymous	11/27	-
13-32912299-T-C	BRCA2	c.3807T>C	p.Val1269Val	Synonymous	11/27	-
11-108137926-G-T	ATM	c.2495G>T	p.Arg832Leu	Missense	17/63	-
11-108175462-G-A	ATM	c.5557G>A	p.Asp1853Asn	Missense	37/63	-
13-32954246-C-T	BRCA2	c.9220C>T	p.Leu3074Leu	Synonymous	24/27	-
10-89624304-C-T	PTEN	c.78C>T	p.Thr26Thr	Synonymous	1/9	-
16-23640966-C-T	PALB2	c.2509G>A	p.Glu837Lys	Missense	5/13	-
10-89624304-C-A	PTEN	c.78C>A	p.Thr26Thr	Synonymous	1/9	-
11-108121767-G-A	ATM	c.1575G>A	p.Lys525Lys	Synonymous	10/63	-
19-1226620-C-T	STK11	c.1276C>T	p.Arg426Trp	Missense	9/10	-
11-108150302-A-G	ATM	c.3369A>G	p.Ala1123Ala	Synonymous	23/63	-
19-1226620-C-A	STK11	c.1276C>A	p.Arg426Arg	Synonymous	9/10	-
19-1226620-C-G	STK11	c.1276C>G	p.Arg426Gly	Missense	9/10	-
17-41223094-T-C	BRCA1	c.4837A>G	p.Ser1613Gly	Missense	15/23	-
11-108170490-C-T	ATM	c.5055C>T	p.Thr1685Thr	Synonymous	34/63	-
13-32907165-A-G	BRCA2	c.1550A>G	p.Asn517Ser	Missense	10/27	-
17-41245390-C-T	BRCA1	c.2158G>A	p.Glu720Lys	Missense	10/23	-
13-32929056-T-G	BRCA2	c.7066T>G	p.Phe2356Val	Missense	14/27	-
16-68862165-C-G	CDH1	c.2253C>G	p.Asn751Lys	Missense	14/16	-
17-29701168-G-C	NF1	c.8452G>C	p.Val2818Leu	Missense	57/57	-
11-108216478-A-G	ATM	c.8427A>G	p.Gln2809Gln	Synonymous	58/63	-
17-41219707-G-A	BRCA1	c.4992C>T	p.Leu1664Leu	Synonymous	16/23	-
17-41256210-T-C	BRCA1	c.370A>G	p.Ile124Val	Missense	6/23	-
17-41256210-T-G	BRCA1	c.370A>C	p.Ile124Leu	Missense	6/23	-
17-41246792-A-G	BRCA1	c.756T>C	p.Arg252Arg	Synonymous	10/23	-
11-108126975-C-A	ATM	c.2158C>A	p.Arg720Ser	Missense	14/63	-
17-7578244-C-A	TP53	c.605G>T	p.Arg202Leu	Missense	6/11	-
13-32912671-G-A	BRCA2	c.4179G>A	p.Ala1393Ala	Synonymous	11/27	-
13-32954041-A-G	BRCA2	c.9108A>G	p.Gln3036Gln	Synonymous	23/27	-
13-32914623-G-T	BRCA2	c.6131G>T	p.Gly2044Val	Missense	11/27	-
13-32914623-G-C	BRCA2	c.6131G>C	p.Gly2044Ala	Missense	11/27	-
13-32914623-G-A	BRCA2	c.6131G>A	p.Gly2044Asp	Missense	11/27	-
13-32914591-A-G	BRCA2	c.6099A>G	p.Ile2033Met	Missense	11/27	-
17-7579705-C-A	TP53	c.91G>T	p.Val31Phe	Missense	3/11	-
16-23641388-G-A	PALB2	c.2087C>T	p.Thr696Met	Missense	5/13	-
19-1221294-G-A	STK11	c.817G>A	p.Ala273Thr	Missense	6/10	-
13-32972526-G-A	BRCA2	c.9876G>A	p.Pro3292Pro	Synonymous	27/27	-
17-41244113-A-G	BRCA1	c.3435T>C	p.Val1145Val	Synonymous	10/23	-
13-32972526-G-T	BRCA2	c.9876G>T	p.Pro3292Pro	Synonymous	27/27	-
17-41226411-G-A	BRCA1	c.4612C>T	p.Gln1538*	Nonsense	14/23	-
13-32913691-C-T	BRCA2	c.5199C>T	p.Ser1733Ser	Synonymous	11/27	-
11-108168108-A-G	ATM	c.5004A>G	p.Leu1668Leu	Synonymous	33/63	-
17-7578283-G-A	TP53	c.566C>T	p.Ala189Val	Missense	6/11	-
17-41203085-G-A	BRCA1	c.5327C>T	p.Pro1776Leu	Missense	20/23	-
16-23640966-C-G	PALB2	c.2509G>C	p.Glu837Gln	Missense	5/13	-
17-29552151-C-A	NF1	c.1884C>A	p.Tyr628*	Nonsense	17/57	-
11-108099970-C-T	ATM	c.251C>T	p.Ala84Val	Missense	4/63	-
13-32911712-A-T	BRCA2	c.3220A>T	p.Ser1074Cys	Missense	11/27	-
11-108121675-A-G	ATM	c.1483A>G	p.Ile495Val	Missense	10/63	-
17-41244465-C-T	BRCA1	c.3083G>A	p.Arg1028His	Missense	10/23	-
11-108224583-C-T	ATM	c.8762C>T	p.Thr2921Met	Missense	60/63	-
17-7576543-C-A	TP53	c.993+310G>T	-	IntronicSNV	-	9/10
17-7576543-C-T	TP53	c.993+310G>A	-	IntronicSNV	-	9/10
13-32913023-G-A	BRCA2	c.4531G>A	p.Glu1511Lys	Missense	11/27	-
10-89717698-T-G	PTEN	c.723T>G	p.Phe241Leu	Missense	7/9	-
11-108198411-A-C	ATM	c.7015A>C	p.Arg2339Arg	Synonymous	48/63	-
17-29667607-G-C	NF1	c.6943G>C	p.Ala2315Pro	Missense	46/57	-
17-29667607-G-A	NF1	c.6943G>A	p.Ala2315Thr	Missense	46/57	-
17-41244982-A-G	BRCA1	c.2566T>C	p.Tyr856His	Missense	10/23	-
13-32914152-C-T	BRCA2	c.5660C>T	p.Thr1887Met	Missense	11/27	-
16-68853227-C-T	CDH1	c.1610C>T	p.Pro537Leu	Missense	11/16	-
17-29683555-A-G	NF1	c.7630A>G	p.Thr2544Ala	Missense	51/57	-
17-29683555-A-C	NF1	c.7630A>C	p.Thr2544Pro	Missense	51/57	-
19-1207086-C-G	STK11	c.174C>G	p.Gly58Gly	Synonymous	1/10	-
11-108142134-G-A	ATM	c.3077+1G>A	-	IntronicSNV	-	20/62
17-29667607-G-T	NF1	c.6943G>T	p.Ala2315Ser	Missense	46/57	-
13-32945130-G-T	BRCA2	c.8525G>T	p.Arg2842Leu	Missense	20/27	-
16-68772305-C-T	CDH1	c.154C>T	p.Leu52Leu	Synonymous	2/16	-
17-7574017-C-G	TP53	c.1010G>C	p.Arg337Pro	Missense	10/11	-
11-108183149-T-C	ATM	c.5930T>C	p.Phe1977Ser	Missense	40/63	-
22-29083913-C-T	CHEK2	c.1733G>A	p.Arg578His	Missense	16/16	-
11-108164144-G-C	ATM	c.4716G>C	p.Lys1572Asn	Missense	31/63	-
11-108142134-G-T	ATM	c.3077+1G>T	-	IntronicSNV	-	20/62
16-23641246-A-G	PALB2	c.2229T>C	p.Tyr743Tyr	Synonymous	5/13	-
17-41222996-C-G	BRCA1	c.4935G>C	p.Arg1645Ser	Missense	15/23	-
19-1223170-C-T	STK11	c.1107C>T	p.Pro369Pro	Synonymous	8/10	-
13-32929388-A-T	BRCA2	c.7398A>T	p.Val2466Val	Synonymous	14/27	-
17-7573948-C-T	TP53	c.1079G>A	p.Gly360Glu	Missense	10/11	-
13-32929388-A-G	BRCA2	c.7398A>G	p.Val2466Val	Synonymous	14/27	-
16-23641594-C-A	PALB2	c.1881G>T	p.Val627Val	Synonymous	5/13	-
16-23641594-C-T	PALB2	c.1881G>A	p.Val627Val	Synonymous	5/13	-
17-29701060-C-A	NF1	c.8344C>A	p.Pro2782Thr	Missense	57/57	-
13-32914817-G-A	BRCA2	c.6325G>A	p.Val2109Ile	Missense	11/27	-
11-108098564-G-A	ATM	c.134G>A	p.Arg45Gln	Missense	3/63	-
16-23641058-G-A	PALB2	c.2417C>T	p.Pro806Leu	Missense	5/13	-
17-41244569-T-C	BRCA1	c.2979A>G	p.Lys993Lys	Synonymous	10/23	-
17-41223094-T-A	BRCA1	c.4837A>T	p.Ser1613Cys	Missense	15/23	-
11-108121544-G-A	ATM	c.1352G>A	p.Arg451His	Missense	10/63	-
22-29091225-C-T	CHEK2	c.1394G>A	p.Ser465Asn	Missense	13/16	-
13-32914640-G-T	BRCA2	c.6148G>T	p.Val2050Leu	Missense	11/27	-
16-68863655-T-C	CDH1	c.2394T>C	p.Leu798Leu	Synonymous	15/16	-
13-32954242-G-A	BRCA2	c.9216G>A	p.Val3072Val	Synonymous	24/27	-
11-108170490-C-G	ATM	c.5055C>G	p.Thr1685Thr	Synonymous	34/63	-
17-29654756-C-T	NF1	c.5445C>T	p.Pro1815Pro	Synonymous	37/57	-
11-108121767-G-T	ATM	c.1575G>T	p.Lys525Asn	Missense	10/63	-
17-29664851-T-G	NF1	c.6594T>G	p.Asp2198Glu	Missense	43/57	-
19-1220702-G-T	STK11	c.720G>T	p.Ser240Ser	Synonymous	5/10	-
19-1220702-G-A	STK11	c.720G>A	p.Ser240Ser	Synonymous	5/10	-
17-41244797-TG-T	BRCA1	c.2751delC	p.Lys918Serfs*82	Frameshift	10/23	-
13-32900264-T-C	BRCA2	c.452T>C	p.Val151Ala	Missense	5/27	-
16-23646191-T-A	PALB2	c.1676A>T	p.Gln559Leu	Missense	4/13	-
13-32954050-G-C	BRCA2	c.9117G>C	p.Pro3039Pro	Synonymous	23/27	-
13-32954050-G-A	BRCA2	c.9117G>A	p.Pro3039Pro	Synonymous	23/27	-
13-32900742-T-G	BRCA2	c.623T>G	p.Val208Gly	Missense	7/27	-
13-32906890-A-G	BRCA2	c.1275A>G	p.Glu425Glu	Synonymous	10/27	-
13-32907165-A-T	BRCA2	c.1550A>T	p.Asn517Ile	Missense	10/27	-
16-68846136-C-T	CDH1	c.1107C>T	p.Asn369Asn	Synonymous	8/16	-
13-32913674-G-A	BRCA2	c.5182G>A	p.Asp1728Asn	Missense	11/27	-
16-23635380-C-T	PALB2	c.2784G>A	p.Val928Val	Synonymous	8/13	-
16-23646191-T-C	PALB2	c.1676A>G	p.Gln559Arg	Missense	4/13	-
13-32954050-G-T	BRCA2	c.9117G>T	p.Pro3039Pro	Synonymous	23/27	-
11-108178644-T-A	ATM	c.5695T>A	p.Cys1899Ser	Missense	38/63	-
13-32972525-C-T	BRCA2	c.9875C>T	p.Pro3292Leu	Missense	27/27	-
17-29559844-T-C	NF1	c.3441T>C	p.Leu1147Leu	Synonymous	26/57	-
19-1226535-G-A	STK11	c.1191G>A	p.Ala397Ala	Synonymous	9/10	-
19-1226535-G-T	STK11	c.1191G>T	p.Ala397Ala	Synonymous	9/10	-
19-1226535-G-C	STK11	c.1191G>C	p.Ala397Ala	Synonymous	9/10	-
13-32915230-A-G	BRCA2	c.6738A>G	p.Pro2246Pro	Synonymous	11/27	-
17-41197760-C-G	BRCA1	c.5527G>C	p.Ala1843Pro	Missense	23/23	-
13-32929297-A-T	BRCA2	c.7307A>T	p.Asn2436Ile	Missense	14/27	-
13-32914021-A-T	BRCA2	c.5529A>T	p.Ala1843Ala	Synonymous	11/27	-
13-32914021-A-C	BRCA2	c.5529A>C	p.Ala1843Ala	Synonymous	11/27	-
13-32930633-C-A	BRCA2	c.7504C>A	p.Arg2502Ser	Missense	15/27	-
13-32914229-T-C	BRCA2	c.5737T>C	p.Cys1913Arg	Missense	11/27	-
13-32893412-C-A	BRCA2	c.266C>A	p.Pro89Gln	Missense	3/27	-
11-108178641-C-T	ATM	c.5692C>T	p.Arg1898*	Nonsense	38/63	-
16-68862117-G-C	CDH1	c.2205G>C	p.Ala735Ala	Synonymous	14/16	-
16-68835594-G-A	CDH1	c.185G>A	p.Gly62Asp	Missense	3/16	-
13-32912008-G-A	BRCA2	c.3516G>A	p.Ser1172Ser	Synonymous	11/27	-
13-32893412-C-T	BRCA2	c.266C>T	p.Pro89Leu	Missense	3/27	-
17-29560209-A-G	NF1	c.3686A>G	p.Asn1229Ser	Missense	27/57	-
16-68867265-A-G	CDH1	c.2512A>G	p.Ser838Gly	Missense	16/16	-
17-29701047-C-T	NF1	c.8331C>T	p.Asn2777Asn	Synonymous	57/57	-
13-32913407-G-C	BRCA2	c.4915G>C	p.Val1639Leu	Missense	11/27	-
17-41246597-T-C	BRCA1	c.951A>G	p.Gln317Gln	Synonymous	10/23	-
13-32914782-C-T	BRCA2	c.6290C>T	p.Thr2097Met	Missense	11/27	-
17-29556173-T-G	NF1	c.2540T>G	p.Leu847Arg	Missense	21/57	-
17-29556173-T-C	NF1	c.2540T>C	p.Leu847Pro	Missense	21/57	-
17-7578262-C-T	TP53	c.587G>A	p.Arg196Gln	Missense	6/11	-
17-7577139-G-A	TP53	c.799C>T	p.Arg267Trp	Missense	8/11	-
19-1226569-C-T	STK11	c.1225C>T	p.Arg409Trp	Missense	9/10	-
13-32930634-G-A	BRCA2	c.7505G>A	p.Arg2502His	Missense	15/27	-
13-32915263-C-T	BRCA2	c.6771C>T	p.Pro2257Pro	Synonymous	11/27	-
11-108150232-C-G	ATM	c.3299C>G	p.Thr1100Arg	Missense	23/63	-
11-108150232-C-T	ATM	c.3299C>T	p.Thr1100Met	Missense	23/63	-
17-7578414-A-G	TP53	c.516T>C	p.Val172Val	Synonymous	5/11	-
11-108126966-C-T	ATM	c.2149C>T	p.Arg717Trp	Missense	14/63	-
17-41243849-T-C	BRCA1	c.3699A>G	p.Lys1233Lys	Synonymous	10/23	-
17-7579546-C-A	TP53	c.141G>T	p.Pro47Pro	Synonymous	4/11	-
17-7579546-C-T	TP53	c.141G>A	p.Pro47Pro	Synonymous	4/11	-
13-32913407-G-A	BRCA2	c.4915G>A	p.Val1639Ile	Missense	11/27	-
19-1226569-C-G	STK11	c.1225C>G	p.Arg409Gly	Missense	9/10	-
16-68835786-C-T	CDH1	c.377C>T	p.Pro126Leu	Missense	3/16	-
16-68835786-C-A	CDH1	c.377C>A	p.Pro126Gln	Missense	3/16	-
16-68835786-C-G	CDH1	c.377C>G	p.Pro126Arg	Missense	3/16	-
19-1223035-G-A	STK11	c.972G>A	p.Pro324Pro	Synonymous	8/10	-
16-23647146-T-C	PALB2	c.721A>G	p.Asn241Asp	Missense	4/13	-
16-23647146-T-G	PALB2	c.721A>C	p.Asn241His	Missense	4/13	-
13-32914328-T-C	BRCA2	c.5836T>C	p.Ser1946Pro	Missense	11/27	-
17-41246181-A-G	BRCA1	c.1367T>C	p.Ile456Thr	Missense	10/23	-
19-1220612-C-A	STK11	c.630C>A	p.Cys210*	Nonsense	5/10	-
19-1220612-C-T	STK11	c.630C>T	p.Cys210Cys	Synonymous	5/10	-
16-23646935-T-C	PALB2	c.932A>G	p.Lys311Arg	Missense	4/13	-
16-23646935-T-G	PALB2	c.932A>C	p.Lys311Thr	Missense	4/13	-
16-68845757-C-G	CDH1	c.1003C>G	p.Arg335Gly	Missense	7/16	-
17-7578463-C-G	TP53	c.467G>C	p.Arg156Pro	Missense	5/11	-
17-7578463-C-T	TP53	c.467G>A	p.Arg156His	Missense	5/11	-
13-32954181-G-T	BRCA2	c.9155G>T	p.Arg3052Leu	Missense	24/27	-
13-32954181-G-A	BRCA2	c.9155G>A	p.Arg3052Gln	Missense	24/27	-
13-32953632-C-A	BRCA2	c.8933C>A	p.Ser2978*	Nonsense	22/27	-
13-32953632-C-G	BRCA2	c.8933C>G	p.Ser2978*	Nonsense	22/27	-
13-32972356-A-T	BRCA2	c.9706A>T	p.Lys3236*	Nonsense	27/27	-
13-32929040-C-T	BRCA2	c.7050C>T	p.Thr2350Thr	Synonymous	14/27	-
17-41215948-G-T	BRCA1	c.5095C>A	p.Arg1699Arg	Synonymous	17/23	-
17-41215948-G-A	BRCA1	c.5095C>T	p.Arg1699Trp	Missense	17/23	-
11-108137925-C-T	ATM	c.2494C>T	p.Arg832Cys	Missense	17/63	-
17-41246191-C-G	BRCA1	c.1357G>C	p.Glu453Gln	Missense	10/23	-
11-108137925-C-A	ATM	c.2494C>A	p.Arg832Ser	Missense	17/63	-
13-32915129-T-C	BRCA2	c.6637T>C	p.Ser2213Pro	Missense	11/27	-
16-23646834-A-G	PALB2	c.1033T>C	p.Leu345Leu	Synonymous	4/13	-
11-108126975-C-T	ATM	c.2158C>T	p.Arg720Cys	Missense	14/63	-
13-32893236-T-C	BRCA2	c.90T>C	p.Asn30Asn	Synonymous	3/27	-
16-68849520-G-A	CDH1	c.1423G>A	p.Val475Met	Missense	10/16	-
10-89692904-C-G	PTEN	c.388C>G	p.Arg130Gly	Missense	5/9	-
16-23646882-G-C	PALB2	c.985C>G	p.Leu329Val	Missense	4/13	-
11-108151833-G-C	ATM	c.3514G>C	p.Ala1172Pro	Missense	24/63	-
13-32914206-A-G	BRCA2	c.5714A>G	p.His1905Arg	Missense	11/27	-
17-41246737-C-T	BRCA1	c.811G>A	p.Val271Met	Missense	10/23	-
13-32906729-A-C	BRCA2	c.1114A>C	p.Asn372His	Missense	10/27	-
17-41246737-C-G	BRCA1	c.811G>C	p.Val271Leu	Missense	10/23	-
13-32914485-A-G	BRCA2	c.5993A>G	p.Gln1998Arg	Missense	11/27	-
13-32914485-A-C	BRCA2	c.5993A>C	p.Gln1998Pro	Missense	11/27	-
16-68847249-G-A	CDH1	c.1171G>A	p.Val391Ile	Missense	9/16	-
16-68847249-G-T	CDH1	c.1171G>T	p.Val391Phe	Missense	9/16	-
11-108138009-G-C	ATM	c.2578G>C	p.Asp860His	Missense	17/63	-
11-108138009-G-A	ATM	c.2578G>A	p.Asp860Asn	Missense	17/63	-
16-68862165-C-T	CDH1	c.2253C>T	p.Asn751Asn	Synonymous	14/16	-
16-23649398-C-T	PALB2	c.101G>A	p.Arg34His	Missense	2/13	-
17-29552242-C-T	NF1	c.1975C>T	p.Arg659Trp	Missense	17/57	-
13-32914174-C-G	BRCA2	c.5682C>G	p.Tyr1894*	Nonsense	11/27	-
17-41209095-G-C	BRCA1	c.5251C>G	p.Arg1751Gly	Missense	19/23	-
13-32914174-C-T	BRCA2	c.5682C>T	p.Tyr1894Tyr	Synonymous	11/27	-
17-29559871-C-A	NF1	c.3468C>A	p.Asn1156Lys	Missense	26/57	-
16-23640970-G-A	PALB2	c.2505C>T	p.Ser835Ser	Synonymous	5/13	-
17-29559871-C-T	NF1	c.3468C>T	p.Asn1156Asn	Synonymous	26/57	-
16-23640970-G-T	PALB2	c.2505C>A	p.Ser835Ser	Synonymous	5/13	-
19-1220597-G-A	STK11	c.615G>A	p.Ala205Ala	Synonymous	5/10	-
11-108170498-T-C	ATM	c.5063T>C	p.Ile1688Thr	Missense	34/63	-
16-23641198-T-C	PALB2	c.2277A>G	p.Gln759Gln	Synonymous	5/13	-
17-29657472-C-G	NF1	c.5705C>G	p.Thr1902Arg	Missense	38/57	-
22-29090054-G-C	CHEK2	c.1556C>G	p.Thr519Arg	Missense	14/16	-
13-32906480-A-G	BRCA2	c.865A>G	p.Asn289Asp	Missense	10/27	-
22-29083956-G-A	CHEK2	c.1690C>T	p.Arg564Trp	Missense	16/16	-
17-29576036-C-T	NF1	c.4009C>T	p.Arg1337Trp	Missense	30/57	-
13-32906480-A-C	BRCA2	c.865A>C	p.Asn289His	Missense	10/27	-
11-108206576-G-A	ATM	c.8156G>A	p.Arg2719His	Missense	56/63	-
17-41242961-C-G	BRCA1	c.4185G>C	p.Gln1395His	Missense	11/23	-
13-32930650-A-G	BRCA2	c.7521A>G	p.Pro2507Pro	Synonymous	15/27	-
17-41244465-C-A	BRCA1	c.3083G>T	p.Arg1028Leu	Missense	10/23	-
17-41242961-C-T	BRCA1	c.4185G>A	p.Gln1395Gln	Synonymous	11/23	-
17-7577120-C-A	TP53	c.818G>T	p.Arg273Leu	Missense	8/11	-
17-7579438-C-T	TP53	c.249G>A	p.Ala83Ala	Synonymous	4/11	-
11-108216581-A-C	ATM	c.8530A>C	p.Ile2844Leu	Missense	58/63	-
17-7577120-C-G	TP53	c.818G>C	p.Arg273Pro	Missense	8/11	-
11-108098555-A-G	ATM	c.125A>G	p.His42Arg	Missense	3/63	-
16-23647023-T-C	PALB2	c.844A>G	p.Arg282Gly	Missense	4/13	-
22-29095854-T-A	CHEK2	c.1109A>T	p.Tyr370Phe	Missense	10/16	-
11-108123554-C-G	ATM	c.1813C>G	p.His605Asp	Missense	12/63	-
19-1219380-G-T	STK11	c.432G>T	p.Pro144Pro	Synonymous	3/10	-
17-41267763-C-T	BRCA1	c.114G>A	p.Lys38Lys	Synonymous	3/23	-
19-1223136-A-G	STK11	c.1073A>G	p.Asp358Gly	Missense	8/10	-
22-29095854-T-C	CHEK2	c.1109A>G	p.Tyr370Cys	Missense	10/16	-
17-29684078-G-A	NF1	c.7776G>A	p.Pro2592Pro	Synonymous	52/57	-
17-29684078-G-C	NF1	c.7776G>C	p.Pro2592Pro	Synonymous	52/57	-
19-1207086-C-T	STK11	c.174C>T	p.Gly58Gly	Synonymous	1/10	-
19-1226621-G-A	STK11	c.1277G>A	p.Arg426Gln	Missense	9/10	-
19-1226621-G-T	STK11	c.1277G>T	p.Arg426Leu	Missense	9/10	-
19-1226621-G-C	STK11	c.1277G>C	p.Arg426Pro	Missense	9/10	-
11-108164131-A-G	ATM	c.4703A>G	p.His1568Arg	Missense	31/63	-
17-41222967-G-A	BRCA1	c.4964C>T	p.Ser1655Phe	Missense	15/23	-
11-108129732-C-T	ATM	c.2396C>T	p.Ala799Val	Missense	16/63	-
13-32910721-T-C	BRCA2	c.2229T>C	p.His743His	Synonymous	11/27	-
19-1226569-C-A	STK11	c.1225C>A	p.Arg409Arg	Synonymous	9/10	-
11-108143552-G-A	ATM	c.3257G>A	p.Arg1086His	Missense	22/63	-
17-7577548-C-A	TP53	c.733G>T	p.Gly245Cys	Missense	7/11	-
11-108143552-G-T	ATM	c.3257G>T	p.Arg1086Leu	Missense	22/63	-
19-1220466-G-C	STK11	c.559G>C	p.Gly187Arg	Missense	4/10	-
16-68863619-C-T	CDH1	c.2358C>T	p.Asp786Asp	Synonymous	15/16	-
13-32930651-G-A	BRCA2	c.7522G>A	p.Gly2508Ser	Missense	15/27	-
11-108114842-C-T	ATM	c.659C>T	p.Ala220Val	Missense	6/63	-
16-23647552-C-T	PALB2	c.315G>A	p.Glu105Glu	Synonymous	4/13	-
16-23647552-C-G	PALB2	c.315G>C	p.Glu105Asp	Missense	4/13	-
11-108173695-C-T	ATM	c.5435C>T	p.Ala1812Val	Missense	36/63	-
17-41245759-C-A	BRCA1	c.1789G>T	p.Glu597*	Nonsense	10/23	-
16-68835642-G-A	CDH1	c.233G>A	p.Gly78Asp	Missense	3/16	-
17-41245759-C-T	BRCA1	c.1789G>A	p.Glu597Lys	Missense	10/23	-
13-32914285-A-G	BRCA2	c.5793A>G	p.Gln1931Gln	Synonymous	11/27	-
17-7577555-G-C	TP53	c.726C>G	p.Cys242Trp	Missense	7/11	-
11-108206685-T-C	ATM	c.8265T>C	p.Tyr2755Tyr	Synonymous	56/63	-
13-32911297-ATAAA-A	BRCA2	c.2805_2808delTAAA	p.Ala938Profs*21	Frameshift	11/27	-
17-7577555-G-A	TP53	c.726C>T	p.Cys242Cys	Synonymous	7/11	-
16-23649273-G-A	PALB2	c.109C>T	p.Arg37Cys	Missense	3/13	-
13-32914894-T-TT	BRCA2	c.6402dupT	p.Asn2135*fs*1	Nonsense	11/27	-
16-23632742-C-T	PALB2	c.3054G>A	p.Glu1018Glu	Synonymous	10/13	-
16-23649273-G-T	PALB2	c.109C>A	p.Arg37Ser	Missense	3/13	-
11-108198458-G-C	ATM	c.7062G>C	p.Ala2354Ala	Synonymous	48/63	-
10-89653834-C-A	PTEN	c.132C>A	p.Gly44Gly	Synonymous	2/9	-
11-108198458-G-A	ATM	c.7062G>A	p.Ala2354Ala	Synonymous	48/63	-
10-89653834-C-T	PTEN	c.132C>T	p.Gly44Gly	Synonymous	2/9	-
17-41246855-C-T	BRCA1	c.693G>A	p.Thr231Thr	Synonymous	10/23	-
17-41246855-C-A	BRCA1	c.693G>T	p.Thr231Thr	Synonymous	10/23	-
13-32912610-T-G	BRCA2	c.4118T>G	p.Met1373Arg	Missense	11/27	-
16-23646911-G-A	PALB2	c.956C>T	p.Ser319Phe	Missense	4/13	-
13-32971139-G-C	BRCA2	c.9606G>C	p.Pro3202Pro	Synonymous	26/27	-
13-32913987-C-A	BRCA2	c.5495C>A	p.Ser1832Tyr	Missense	11/27	-
13-32913987-C-G	BRCA2	c.5495C>G	p.Ser1832Cys	Missense	11/27	-
16-68835779-C-T	CDH1	c.370C>T	p.Arg124Cys	Missense	3/16	-
13-32906876-C-G	BRCA2	c.1261C>G	p.Gln421Glu	Missense	10/27	-
13-32906876-C-T	BRCA2	c.1261C>T	p.Gln421*	Nonsense	10/27	-
17-29556385-A-T	NF1	c.2752A>T	p.Lys918*	Nonsense	21/57	-
17-29556374-G-A	NF1	c.2741G>A	p.Arg914Gln	Missense	21/57	-
17-29663377-A-C	NF1	c.5970A>C	p.Leu1990Leu	Synonymous	40/57	-
17-29663377-A-G	NF1	c.5970A>G	p.Leu1990Leu	Synonymous	40/57	-
17-29667606-C-T	NF1	c.6942C>T	p.Thr2314Thr	Synonymous	46/57	-
17-29667606-C-G	NF1	c.6942C>G	p.Thr2314Thr	Synonymous	46/57	-
13-32937586-G-A	BRCA2	c.8247G>A	p.Gln2749Gln	Synonymous	18/27	-
17-29553484-C-T	NF1	c.2033C>T	p.Pro678Leu	Missense	18/57	-
13-32911300-AACAA-A	BRCA2	c.2808_2811delACAA	p.Ala938Profs*21	Frameshift	11/27	-
17-29684292-A-G	NF1	c.7812A>G	p.Thr2604Thr	Synonymous	53/57	-
11-108192040-G-A	ATM	c.6465G>A	p.Val2155Val	Synonymous	45/63	-
13-32893291-G-C	BRCA2	c.145G>C	p.Glu49Gln	Missense	3/27	-
16-23619299-G-A	PALB2	c.3236C>T	p.Ala1079Val	Missense	12/13	-
13-32893291-G-T	BRCA2	c.145G>T	p.Glu49*	Nonsense	3/27	-
17-41247917-G-A	BRCA1	c.616C>T	p.Gln206*	Nonsense	9/23	-
16-68835594-G-T	CDH1	c.185G>T	p.Gly62Val	Missense	3/16	-
17-41223119-T-C	BRCA1	c.4812A>G	p.Gln1604Gln	Synonymous	15/23	-
16-23637664-C-T	PALB2	c.2641G>A	p.Gly881Ser	Missense	7/13	-
13-32911712-A-G	BRCA2	c.3220A>G	p.Ser1074Gly	Missense	11/27	-
17-29585450-C-A	NF1	c.4199C>A	p.Pro1400Gln	Missense	31/57	-
17-29585450-C-G	NF1	c.4199C>G	p.Pro1400Arg	Missense	31/57	-
17-29585450-C-T	NF1	c.4199C>T	p.Pro1400Leu	Missense	31/57	-
11-108138041-C-T	ATM	c.2610C>T	p.Asn870Asn	Synonymous	17/63	-
11-108138041-C-G	ATM	c.2610C>G	p.Asn870Lys	Missense	17/63	-
17-41234440-TTCT-TTCTTTCT	BRCA1	c.4335_4338dup	p.Gln1447Argfs*16	Frameshift	12/23	-
16-68846092-T-C	CDH1	c.1063T>C	p.Leu355Leu	Synonymous	8/16	-
13-32911295-G-A	BRCA2	c.2803G>A	p.Asp935Asn	Missense	11/27	-
16-68845620-C-T	CDH1	c.866C>T	p.Ala289Val	Missense	7/16	-
17-41245683-G-A	BRCA1	c.1865C>T	p.Ala622Val	Missense	10/23	-
10-89690827-C-A	PTEN	c.234C>A	p.Thr78Thr	Synonymous	4/9	-
17-41245683-G-C	BRCA1	c.1865C>G	p.Ala622Gly	Missense	10/23	-
22-29083956-G-C	CHEK2	c.1690C>G	p.Arg564Gly	Missense	16/16	-
22-29090054-G-T	CHEK2	c.1556C>A	p.Thr519Lys	Missense	14/16	-
22-29092952-T-C	CHEK2	c.1161A>G	p.Ile387Met	Missense	11/16	-
22-29083956-G-T	CHEK2	c.1690C>A	p.Arg564Arg	Synonymous	16/16	-
13-32910678-T-C	BRCA2	c.2186T>C	p.Ile729Thr	Missense	11/27	-
17-7578372-A-G	TP53	c.558T>C	p.Asp186Asp	Synonymous	5/11	-
17-7578372-A-T	TP53	c.558T>A	p.Asp186Glu	Missense	5/11	-
19-1220603-C-T	STK11	c.621C>T	p.Asp207Asp	Synonymous	5/10	-
17-41243899-A-T	BRCA1	c.3649T>A	p.Ser1217Thr	Missense	10/23	-
17-41219633-A-C	BRCA1	c.5066T>G	p.Met1689Arg	Missense	16/23	-
17-41219633-A-G	BRCA1	c.5066T>C	p.Met1689Thr	Missense	16/23	-
16-23619239-G-A	PALB2	c.3296C>T	p.Thr1099Met	Missense	12/13	-
16-23619239-G-C	PALB2	c.3296C>G	p.Thr1099Arg	Missense	12/13	-
17-41243899-A-G	BRCA1	c.3649T>C	p.Ser1217Pro	Missense	10/23	-
17-29490279-C-T	NF1	c.364C>T	p.His122Tyr	Missense	4/57	-
17-41246856-G-A	BRCA1	c.692C>T	p.Thr231Met	Missense	10/23	-
13-32954037-A-T	BRCA2	c.9104A>T	p.Tyr3035Phe	Missense	23/27	-
13-32954037-A-C	BRCA2	c.9104A>C	p.Tyr3035Ser	Missense	23/27	-
11-108143542-C-T	ATM	c.3247C>T	p.His1083Tyr	Missense	22/63	-
17-41215915-C-T	BRCA1	c.5128G>A	p.Gly1710Arg	Missense	17/23	-
17-41215915-C-A	BRCA1	c.5128G>T	p.Gly1710*	Nonsense	17/23	-
17-7578522-T-C	TP53	c.408A>G	p.Gln136Gln	Synonymous	5/11	-
13-32930687-C-T	BRCA2	c.7558C>T	p.Arg2520*	Nonsense	15/27	-
11-108200991-G-A	ATM	c.7358G>A	p.Arg2453His	Missense	50/63	-
17-7578522-T-G	TP53	c.408A>C	p.Gln136His	Missense	5/11	-
16-23641156-A-C	PALB2	c.2319T>G	p.Thr773Thr	Synonymous	5/13	-
16-23641156-A-G	PALB2	c.2319T>C	p.Thr773Thr	Synonymous	5/13	-
13-32907359-A-C	BRCA2	c.1744A>C	p.Thr582Pro	Missense	10/27	-
13-32907359-A-G	BRCA2	c.1744A>G	p.Thr582Ala	Missense	10/27	-
16-68845648-C-T	CDH1	c.894C>T	p.Ala298Ala	Synonymous	7/16	-
16-68842668-G-A	CDH1	c.604G>A	p.Val202Ile	Missense	5/16	-
16-68835644-A-G	CDH1	c.235A>G	p.Thr79Ala	Missense	3/16	-
17-7579882-C-G	TP53	c.31G>C	p.Glu11Gln	Missense	2/11	-
13-32968839-C-A	BRCA2	c.9270C>A	p.Phe3090Leu	Missense	25/27	-
13-32914814-C-T	BRCA2	c.6322C>T	p.Arg2108Cys	Missense	11/27	-
17-41276105-T-C	BRCA1	c.9A>G	p.Leu3Leu	Synonymous	2/23	-
16-68842668-G-C	CDH1	c.604G>C	p.Val202Leu	Missense	5/16	-
17-7578470-C-T	TP53	c.460G>A	p.Gly154Ser	Missense	5/11	-
17-41276105-T-A	BRCA1	c.9A>T	p.Leu3Phe	Missense	2/23	-
11-108175456-C-T	ATM	c.5551C>T	p.Leu1851Phe	Missense	37/63	-
10-89712007-G-A	PTEN	c.625G>A	p.Gly209Arg	Missense	6/9	-
22-29090061-G-T	CHEK2	c.1549C>A	p.Arg517Ser	Missense	14/16	-
13-32893361-A-T	BRCA2	c.215A>T	p.Asn72Ile	Missense	3/27	-
16-68847374-C-G	CDH1	c.1296C>G	p.Asn432Lys	Missense	9/16	-
22-29121266-G-C	CHEK2	c.538C>G	p.Arg180Gly	Missense	4/16	-
22-29121266-G-A	CHEK2	c.538C>T	p.Arg180*	Nonsense	4/16	-
13-32929178-G-A	BRCA2	c.7188G>A	p.Leu2396Leu	Synonymous	14/27	-
13-32929178-G-T	BRCA2	c.7188G>T	p.Leu2396Phe	Missense	14/27	-
10-89712007-G-T	PTEN	c.625G>T	p.Gly209*	Nonsense	6/9	-
13-32945109-C-G	BRCA2	c.8504C>G	p.Ser2835*	Nonsense	20/27	-
22-29090061-G-C	CHEK2	c.1549C>G	p.Arg517Gly	Missense	14/16	-
16-68863607-G-A	CDH1	c.2346G>A	p.Val782Val	Synonymous	15/16	-
17-7578470-C-G	TP53	c.460G>C	p.Gly154Arg	Missense	5/11	-
17-29654671-C-T	NF1	c.5360C>T	p.Thr1787Met	Missense	37/57	-
13-32914640-G-A	BRCA2	c.6148G>A	p.Val2050Ile	Missense	11/27	-
11-108151787-G-A	ATM	c.3468G>A	p.Thr1156Thr	Synonymous	24/63	-
10-89717713-G-A	PTEN	c.738G>A	p.Pro246Pro	Synonymous	7/9	-
11-108236206-C-T	ATM	c.9142C>T	p.Leu3048Phe	Missense	63/63	-
17-41246724-C-T	BRCA1	c.824G>A	p.Gly275Asp	Missense	10/23	-
17-41223118-A-G	BRCA1	c.4813T>C	p.Leu1605Leu	Synonymous	15/23	-
17-41267797-C-T	BRCA1	c.81-1G>A	-	IntronicSNV	-	2/22
17-41223118-A-C	BRCA1	c.4813T>G	p.Leu1605Val	Missense	15/23	-
17-41223118-A-T	BRCA1	c.4813T>A	p.Leu1605Met	Missense	15/23	-
13-32972763-T-C	BRCA2	c.10113T>C	p.Thr3371Thr	Synonymous	27/27	-
17-7578210-T-C	TP53	c.639A>G	p.Arg213Arg	Synonymous	6/11	-
11-108137985-C-T	ATM	c.2554C>T	p.Gln852*	Nonsense	17/63	-
11-108114792-C-T	ATM	c.609C>T	p.Asp203Asp	Synonymous	6/63	-
13-32968844-A-T	BRCA2	c.9275A>T	p.Tyr3092Phe	Missense	25/27	-
13-32911954-C-G	BRCA2	c.3462C>G	p.Thr1154Thr	Synonymous	11/27	-
17-41251831-G-T	BRCA1	c.508C>A	p.Arg170Arg	Synonymous	7/23	-
17-41244612-C-A	BRCA1	c.2936G>T	p.Arg979Leu	Missense	10/23	-
11-108175539-G-T	ATM	c.5634G>T	p.Ser1878Ser	Synonymous	37/63	-
13-32911888-A-C	BRCA2	c.3396A>C	p.Lys1132Asn	Missense	11/27	-
13-32911888-A-G	BRCA2	c.3396A>G	p.Lys1132Lys	Synonymous	11/27	-
17-41245237-A-G	BRCA1	c.2311T>C	p.Leu771Leu	Synonymous	10/23	-
13-32900706-G-T	BRCA2	c.587G>T	p.Ser196Ile	Missense	7/27	-
13-32945109-C-A	BRCA2	c.8504C>A	p.Ser2835*	Nonsense	20/27	-
17-41267797-C-G	BRCA1	c.81-1G>C	-	IntronicSNV	-	2/22
16-68842395-G-C	CDH1	c.456G>C	p.Gln152His	Missense	4/16	-
17-7578210-T-A	TP53	c.639A>T	p.Arg213Arg	Synonymous	6/11	-
13-32968844-A-C	BRCA2	c.9275A>C	p.Tyr3092Ser	Missense	25/27	-
16-68867342-C-T	CDH1	c.2589C>T	p.Asn863Asn	Synonymous	16/16	-
17-41244984-T-G	BRCA1	c.2564A>C	p.Gln855Pro	Missense	10/23	-
17-41244984-T-A	BRCA1	c.2564A>T	p.Gln855Leu	Missense	10/23	-
13-32913077-G-A	BRCA2	c.4585G>A	p.Gly1529Arg	Missense	11/27	-
13-32937526-G-T	BRCA2	c.8187G>T	p.Lys2729Asn	Missense	18/27	-
16-68863630-C-T	CDH1	c.2369C>T	p.Thr790Ile	Missense	15/16	-
19-1221227-G-A	STK11	c.750G>A	p.Thr250Thr	Synonymous	6/10	-
22-29130442-G-A	CHEK2	c.268C>T	p.Pro90Ser	Missense	2/16	-
11-108175539-G-A	ATM	c.5634G>A	p.Ser1878Ser	Synonymous	37/63	-
13-32903579-G-A	BRCA2	c.632-1G>A	-	IntronicSNV	-	7/26
13-32953617-G-A	BRCA2	c.8918G>A	p.Arg2973His	Missense	22/27	-
16-23647487-T-C	PALB2	c.380A>G	p.His127Arg	Missense	4/13	-
22-29121241-C-T	CHEK2	c.563G>A	p.Arg188Gln	Missense	4/16	-
11-108159732-C-T	ATM	c.4138C>T	p.His1380Tyr	Missense	28/63	-
22-29121241-C-G	CHEK2	c.563G>C	p.Arg188Pro	Missense	4/16	-
17-41258531-G-A	BRCA1	c.154C>T	p.Leu52Phe	Missense	4/23	-
16-23647109-A-AA	PALB2	c.758dupT	p.Ser254Ilefs*3	Frameshift	4/13	-
22-29090061-G-A	CHEK2	c.1549C>T	p.Arg517Cys	Missense	14/16	-
13-32903606-TGT-T	BRCA2	c.658_659delGT	p.Val220Ilefs*4	Frameshift	8/27	-
17-41258531-G-T	BRCA1	c.154C>A	p.Leu52Ile	Missense	4/23	-
13-32945167-T-G	BRCA2	c.8562T>G	p.Tyr2854*	Nonsense	20/27	-
13-32945167-T-A	BRCA2	c.8562T>A	p.Tyr2854*	Nonsense	20/27	-
13-32945167-T-C	BRCA2	c.8562T>C	p.Tyr2854Tyr	Synonymous	20/27	-
16-68863674-G-A	CDH1	c.2413G>A	p.Asp805Asn	Missense	15/16	-
11-108122704-A-G	ATM	c.1748A>G	p.Tyr583Cys	Missense	11/63	-
16-68772305-C-G	CDH1	c.154C>G	p.Leu52Val	Missense	2/16	-
17-29560087-A-G	NF1	c.3564A>G	p.Gln1188Gln	Synonymous	27/57	-
17-41246037-C-T	BRCA1	c.1511G>A	p.Arg504His	Missense	10/23	-
16-68842419-C-T	CDH1	c.480C>T	p.Pro160Pro	Synonymous	4/16	-
17-41244004-G-A	BRCA1	c.3544C>T	p.Gln1182*	Nonsense	10/23	-
13-32912395-T-C	BRCA2	c.3903T>C	p.Thr1301Thr	Synonymous	11/27	-
11-108201015-G-C	ATM	c.7382G>C	p.Arg2461Pro	Missense	50/63	-
13-32913027-G-C	BRCA2	c.4535G>C	p.Arg1512Pro	Missense	11/27	-
11-108160359-T-A	ATM	c.4267T>A	p.Cys1423Ser	Missense	29/63	-
13-32929042-C-T	BRCA2	c.7052C>T	p.Ala2351Val	Missense	14/27	-
17-41244405-C-T	BRCA1	c.3143G>A	p.Gly1048Asp	Missense	10/23	-
11-108143287-T-C	ATM	c.3106T>C	p.Phe1036Leu	Missense	21/63	-
16-23646675-C-T	PALB2	c.1192G>A	p.Val398Met	Missense	4/13	-
13-32929042-C-G	BRCA2	c.7052C>G	p.Ala2351Gly	Missense	14/27	-
11-108124764-G-A	ATM	c.2122G>A	p.Glu708Lys	Missense	13/63	-
11-108201015-G-A	ATM	c.7382G>A	p.Arg2461His	Missense	50/63	-
17-41243801-G-T	BRCA1	c.3747C>A	p.Thr1249Thr	Synonymous	10/23	-
17-41243801-G-C	BRCA1	c.3747C>G	p.Thr1249Thr	Synonymous	10/23	-
17-41243801-G-A	BRCA1	c.3747C>T	p.Thr1249Thr	Synonymous	10/23	-
19-1221218-C-T	STK11	c.741C>T	p.Asn247Asn	Synonymous	6/10	-
11-108236086-C-G	ATM	c.9022C>G	p.Arg3008Gly	Missense	63/63	-
11-108236086-C-T	ATM	c.9022C>T	p.Arg3008Cys	Missense	63/63	-
13-32907183-A-G	BRCA2	c.1568A>G	p.His523Arg	Missense	10/27	-
16-23641409-G-A	PALB2	c.2066C>T	p.Ser689Leu	Missense	5/13	-
13-32907183-A-T	BRCA2	c.1568A>T	p.His523Leu	Missense	10/27	-
13-32914592-C-T	BRCA2	c.6100C>T	p.Arg2034Cys	Missense	11/27	-
13-32914592-C-A	BRCA2	c.6100C>A	p.Arg2034Ser	Missense	11/27	-
10-89720852-C-T	PTEN	c.1003C>T	p.Arg335*	Nonsense	8/9	-
16-68855966-G-T	CDH1	c.1774G>T	p.Ala592Ser	Missense	12/16	-
16-68855966-G-A	CDH1	c.1774G>A	p.Ala592Thr	Missense	12/16	-
10-89720852-C-A	PTEN	c.1003C>A	p.Arg335Arg	Synonymous	8/9	-
13-32929011-C-T	BRCA2	c.7021C>T	p.Arg2341Cys	Missense	14/27	-
13-32912812-A-G	BRCA2	c.4320A>G	p.Lys1440Lys	Synonymous	11/27	-
17-41203106-T-C	BRCA1	c.5306A>G	p.Tyr1769Cys	Missense	20/23	-
16-23647575-T-C	PALB2	c.292A>G	p.Ile98Val	Missense	4/13	-
17-41276043-C-T	BRCA1	c.71G>A	p.Cys24Tyr	Missense	2/23	-
22-29107934-C-T	CHEK2	c.884G>A	p.Ser295Asn	Missense	7/16	-
11-108204615-G-A	ATM	c.7930G>A	p.Gly2644Ser	Missense	54/63	-
11-108186600-T-C	ATM	c.6057T>C	p.Tyr2019Tyr	Synonymous	41/63	-
11-108172385-C-T	ATM	c.5188C>T	p.Arg1730*	Nonsense	35/63	-
19-1218482-C-T	STK11	c.357C>T	p.Asn119Asn	Synonymous	2/10	-
11-108143283-T-G	ATM	c.3102T>G	p.Tyr1034*	Nonsense	21/63	-
11-108143283-T-C	ATM	c.3102T>C	p.Tyr1034Tyr	Synonymous	21/63	-
11-108204615-G-C	ATM	c.7930G>C	p.Gly2644Arg	Missense	54/63	-
17-41246346-C-G	BRCA1	c.1202G>C	p.Gly401Ala	Missense	10/23	-
16-23637632-G-C	PALB2	c.2673C>G	p.Cys891Trp	Missense	7/13	-
16-23637632-G-A	PALB2	c.2673C>T	p.Cys891Cys	Synonymous	7/13	-
16-23637632-G-T	PALB2	c.2673C>A	p.Cys891*	Nonsense	7/13	-
11-108206651-A-C	ATM	c.8231A>C	p.Glu2744Ala	Missense	56/63	-
13-32906847-T-C	BRCA2	c.1232T>C	p.Ile411Thr	Missense	10/27	-
17-29508775-G-A	NF1	c.702G>A	p.Leu234Leu	Synonymous	7/57	-
17-41246346-C-T	BRCA1	c.1202G>A	p.Gly401Glu	Missense	10/23	-
22-29083950-G-T	CHEK2	c.1696C>A	p.Arg566Ser	Missense	16/16	-
17-7576568-C-T	TP53	c.993+285G>A	-	IntronicSNV	-	9/10
22-29083950-G-C	CHEK2	c.1696C>G	p.Arg566Gly	Missense	16/16	-
17-41243502-G-A	BRCA1	c.4046C>T	p.Thr1349Met	Missense	10/23	-
17-41243502-G-C	BRCA1	c.4046C>G	p.Thr1349Arg	Missense	10/23	-
19-1226491-C-G	STK11	c.1147C>G	p.Arg383Gly	Missense	9/10	-
17-7577091-G-C	TP53	c.847C>G	p.Arg283Gly	Missense	8/11	-
17-41245932-G-T	BRCA1	c.1616C>A	p.Thr539Lys	Missense	10/23	-
13-32945110-A-G	BRCA2	c.8505A>G	p.Ser2835Ser	Synonymous	20/27	-
17-41245932-G-A	BRCA1	c.1616C>T	p.Thr539Met	Missense	10/23	-
19-1223126-G-C	STK11	c.1063G>C	p.Asp355His	Missense	8/10	-
17-7576541-G-A	TP53	c.993+312C>T	-	IntronicSNV	-	9/10
19-1221967-G-A	STK11	c.882G>A	p.Pro294Pro	Synonymous	7/10	-
16-23641246-A-T	PALB2	c.2229T>A	p.Tyr743*	Nonsense	5/13	-
19-1220466-G-A	STK11	c.559G>A	p.Gly187Ser	Missense	4/10	-
17-41251811-C-T	BRCA1	c.528G>A	p.Thr176Thr	Synonymous	7/23	-
17-41243988-C-T	BRCA1	c.3560G>A	p.Ser1187Asn	Missense	10/23	-
17-29552241-C-A	NF1	c.1974C>A	p.Leu658Leu	Synonymous	17/57	-
16-23641057-C-A	PALB2	c.2418G>T	p.Pro806Pro	Synonymous	5/13	-
10-89720804-A-AA	PTEN	c.955dupA	p.Thr319Asnfs*6	Frameshift	8/9	-
17-29552241-C-T	NF1	c.1974C>T	p.Leu658Leu	Synonymous	17/57	-
17-29497004-G-A	NF1	c.575G>A	p.Arg192Gln	Missense	5/57	-
13-32913662-A-G	BRCA2	c.5170A>G	p.Ile1724Val	Missense	11/27	-
17-29676194-C-T	NF1	c.7183C>T	p.Leu2395Leu	Synonymous	48/57	-
17-41197784-G-A	BRCA1	c.5503C>T	p.Arg1835*	Nonsense	23/23	-
11-108155132-G-A	ATM	c.3925G>A	p.Ala1309Thr	Missense	26/63	-
17-41215969-C-G	BRCA1	c.5075-1G>C	-	IntronicSNV	-	16/22
17-41215969-C-T	BRCA1	c.5075-1G>A	-	IntronicSNV	-	16/22
17-41215969-C-A	BRCA1	c.5075-1G>T	-	IntronicSNV	-	16/22
13-32972800-C-T	BRCA2	c.10150C>T	p.Arg3384*	Nonsense	27/27	-
22-29107975-G-A	CHEK2	c.843C>T	p.Phe281Phe	Synonymous	7/16	-
17-7579441-C-T	TP53	c.246G>A	p.Pro82Pro	Synonymous	4/11	-
13-32972800-C-G	BRCA2	c.10150C>G	p.Arg3384Gly	Missense	27/27	-
19-1226538-G-C	STK11	c.1194G>C	p.Ala398Ala	Synonymous	9/10	-
11-108175550-G-C	ATM	c.5645G>C	p.Arg1882Pro	Missense	37/63	-
22-29121015-C-T	CHEK2	c.671G>A	p.Arg224His	Missense	5/16	-
16-23637698-G-A	PALB2	c.2607C>T	p.Ser869Ser	Synonymous	7/13	-
17-29556369-A-G	NF1	c.2736A>G	p.Gln912Gln	Synonymous	21/57	-
16-68867228-G-A	CDH1	c.2475G>A	p.Pro825Pro	Synonymous	16/16	-
11-108235879-C-T	ATM	c.8921C>T	p.Pro2974Leu	Missense	62/63	-
11-108206607-A-C	ATM	c.8187A>C	p.Gln2729His	Missense	56/63	-
11-108206607-A-T	ATM	c.8187A>T	p.Gln2729His	Missense	56/63	-
11-108188234-T-C	ATM	c.6333T>C	p.His2111His	Synonymous	43/63	-
17-41244526-T-C	BRCA1	c.3022A>G	p.Met1008Val	Missense	10/23	-
17-41215389-C-T	BRCA1	c.5154G>A	p.Trp1718*	Nonsense	18/23	-
17-41215389-C-A	BRCA1	c.5154G>T	p.Trp1718Cys	Missense	18/23	-
17-41244526-T-G	BRCA1	c.3022A>C	p.Met1008Leu	Missense	10/23	-
16-68867388-G-A	CDH1	c.2635G>A	p.Gly879Ser	Missense	16/16	-
13-32907014-A-T	BRCA2	c.1399A>T	p.Lys467*	Nonsense	10/27	-
16-68867388-G-C	CDH1	c.2635G>C	p.Gly879Arg	Missense	16/16	-
11-108160424-G-A	ATM	c.4332G>A	p.Leu1444Leu	Synonymous	29/63	-
11-108160424-G-C	ATM	c.4332G>C	p.Leu1444Leu	Synonymous	29/63	-
11-108200961-G-A	ATM	c.7328G>A	p.Arg2443Gln	Missense	50/63	-
11-108203619-C-T	ATM	c.7919C>T	p.Thr2640Ile	Missense	53/63	-
16-68847239-C-T	CDH1	c.1161C>T	p.Asn387Asn	Synonymous	9/16	-
13-32893420-C-T	BRCA2	c.274C>T	p.Gln92*	Nonsense	3/27	-
11-108165736-A-C	ATM	c.4859A>C	p.Gln1620Pro	Missense	32/63	-
11-108100042-C-G	ATM	c.323C>G	p.Ala108Gly	Missense	4/63	-
17-41244100-G-A	BRCA1	c.3448C>T	p.Pro1150Ser	Missense	10/23	-
17-29548980-T-C	NF1	c.1721+33T>C	-	IntronicSNV	-	15/56
13-32913091-A-C	BRCA2	c.4599A>C	p.Lys1533Asn	Missense	11/27	-
17-29585451-G-T	NF1	c.4200G>T	p.Pro1400Pro	Synonymous	31/57	-
17-29585451-G-A	NF1	c.4200G>A	p.Pro1400Pro	Synonymous	31/57	-
16-68862117-G-A	CDH1	c.2205G>A	p.Ala735Ala	Synonymous	14/16	-
11-108099977-A-G	ATM	c.258A>G	p.Thr86Thr	Synonymous	4/63	-
13-32906673-C-T	BRCA2	c.1058C>T	p.Ser353Leu	Missense	10/27	-
19-1226534-C-A	STK11	c.1190C>A	p.Ala397Glu	Missense	9/10	-
19-1223171-G-A	STK11	c.1108G>A	p.Gly370Arg	Missense	8/10	-
19-1226534-C-T	STK11	c.1190C>T	p.Ala397Val	Missense	9/10	-
17-41203085-G-T	BRCA1	c.5327C>A	p.Pro1776His	Missense	20/23	-
17-7574017-C-A	TP53	c.1010G>T	p.Arg337Leu	Missense	10/11	-
11-108216545-C-T	ATM	c.8494C>T	p.Arg2832Cys	Missense	58/63	-
17-41244429-C-T	BRCA1	c.3119G>A	p.Ser1040Asn	Missense	10/23	-
17-7574017-C-T	TP53	c.1010G>A	p.Arg337His	Missense	10/11	-
17-29667656-A-G	NF1	c.6992A>G	p.Asn2331Ser	Missense	46/57	-
11-108173748-A-G	ATM	c.5488A>G	p.Met1830Val	Missense	36/63	-
17-41244429-C-G	BRCA1	c.3119G>C	p.Ser1040Thr	Missense	10/23	-
13-32930598-T-C	BRCA2	c.7469T>C	p.Ile2490Thr	Missense	15/27	-
17-7573948-C-G	TP53	c.1079G>C	p.Gly360Ala	Missense	10/11	-
17-29686024-G-A	NF1	c.8088G>A	p.Pro2696Pro	Synonymous	55/57	-
13-32893381-A-G	BRCA2	c.235A>G	p.Ile79Val	Missense	3/27	-
17-41246753-A-G	BRCA1	c.795T>C	p.Ser265Ser	Synonymous	10/23	-
16-68846047-A-G	CDH1	c.1018A>G	p.Thr340Ala	Missense	8/16	-
16-68846047-A-T	CDH1	c.1018A>T	p.Thr340Ser	Missense	8/16	-
16-23637631-C-T	PALB2	c.2674G>A	p.Glu892Lys	Missense	7/13	-
16-23647638-A-G	PALB2	c.229T>C	p.Cys77Arg	Missense	4/13	-
16-23637631-C-A	PALB2	c.2674G>T	p.Glu892*	Nonsense	7/13	-
16-23641146-C-T	PALB2	c.2329G>A	p.Asp777Asn	Missense	5/13	-
16-68844111-C-G	CDH1	c.699C>G	p.His233Gln	Missense	6/16	-
16-68844111-C-T	CDH1	c.699C>T	p.His233His	Synonymous	6/16	-
10-89692904-C-T	PTEN	c.388C>T	p.Arg130*	Nonsense	5/9	-
16-68867391-G-C	CDH1	c.2638G>C	p.Glu880Gln	Missense	16/16	-
17-41244796-T-TA	BRCA1	c.2751_2752insT	p.Lys918*fs*1	Nonsense	10/23	-
17-29664860-G-A	NF1	c.6603G>A	p.Thr2201Thr	Synonymous	43/57	-
17-29664860-G-C	NF1	c.6603G>C	p.Thr2201Thr	Synonymous	43/57	-
19-1223080-G-A	STK11	c.1017G>A	p.Pro339Pro	Synonymous	8/10	-
19-1223080-G-C	STK11	c.1017G>C	p.Pro339Pro	Synonymous	8/10	-
19-1221278-C-T	STK11	c.801C>T	p.Ile267Ile	Synonymous	6/10	-
16-68857441-T-C	CDH1	c.2076T>C	p.Ala692Ala	Synonymous	13/16	-
16-23641247-T-C	PALB2	c.2228A>G	p.Tyr743Cys	Missense	5/13	-
16-23641247-T-A	PALB2	c.2228A>T	p.Tyr743Phe	Missense	5/13	-
13-32893224-A-G	BRCA2	c.78A>G	p.Pro26Pro	Synonymous	3/27	-
19-1220705-T-C	STK11	c.723T>C	p.Ala241Ala	Synonymous	5/10	-
13-32905116-G-A	BRCA2	c.742G>A	p.Ala248Thr	Missense	9/27	-
17-41234431-T-C	BRCA1	c.4347A>G	p.Thr1449Thr	Synonymous	12/23	-
13-32972548-C-T	BRCA2	c.9898C>T	p.Pro3300Ser	Missense	27/27	-
10-89690827-C-T	PTEN	c.234C>T	p.Thr78Thr	Synonymous	4/9	-
13-32968844-A-G	BRCA2	c.9275A>G	p.Tyr3092Cys	Missense	25/27	-
17-41251831-G-A	BRCA1	c.508C>T	p.Arg170Trp	Missense	7/23	-
13-32972548-C-A	BRCA2	c.9898C>A	p.Pro3300Thr	Missense	27/27	-
11-108119802-C-A	ATM	c.1208C>A	p.Ser403*	Nonsense	9/63	-
11-108117764-T-C	ATM	c.975T>C	p.His325His	Synonymous	8/63	-
10-89717676-G-A	PTEN	c.701G>A	p.Arg234Gln	Missense	7/9	-
13-32903579-G-C	BRCA2	c.632-1G>C	-	IntronicSNV	-	7/26
13-32911887-A-G	BRCA2	c.3395A>G	p.Lys1132Arg	Missense	11/27	-
17-41244984-T-C	BRCA1	c.2564A>G	p.Gln855Arg	Missense	10/23	-
22-29085152-A-C	CHEK2	c.1642T>G	p.Ser548Ala	Missense	15/16	-
22-29085152-A-G	CHEK2	c.1642T>C	p.Ser548Pro	Missense	15/16	-
13-32968855-G-A	BRCA2	c.9286G>A	p.Glu3096Lys	Missense	25/27	-
16-23614962-A-G	PALB2	c.3379T>C	p.Cys1127Arg	Missense	13/13	-
22-29092961-G-A	CHEK2	c.1152C>T	p.Asn384Asn	Synonymous	11/16	-
13-32968855-G-T	BRCA2	c.9286G>T	p.Glu3096*	Nonsense	25/27	-
17-41256154-G-A	BRCA1	c.426C>T	p.Pro142Pro	Synonymous	6/23	-
17-41249284-G-T	BRCA1	c.570C>A	p.Thr190Thr	Synonymous	8/23	-
17-41256154-G-C	BRCA1	c.426C>G	p.Pro142Pro	Synonymous	6/23	-
17-7578414-A-C	TP53	c.516T>G	p.Val172Val	Synonymous	5/11	-
17-41256153-C-A	BRCA1	c.427G>T	p.Glu143*	Nonsense	6/23	-
16-23647514-A-G	PALB2	c.353T>C	p.Ile118Thr	Missense	4/13	-
11-108186756-C-T	ATM	c.6114C>T	p.His2038His	Synonymous	42/63	-
17-29533389-G-A	NF1	c.1392G>A	p.Pro464Pro	Synonymous	12/57	-
17-41243988-C-G	BRCA1	c.3560G>C	p.Ser1187Thr	Missense	10/23	-
17-29533389-G-T	NF1	c.1392G>T	p.Pro464Pro	Synonymous	12/57	-
16-68847239-C-A	CDH1	c.1161C>A	p.Asn387Lys	Missense	9/16	-
17-29560153-A-G	NF1	c.3630A>G	p.Glu1210Glu	Synonymous	27/57	-
13-32929116-G-A	BRCA2	c.7126G>A	p.Ala2376Thr	Missense	14/27	-
13-32929116-G-C	BRCA2	c.7126G>C	p.Ala2376Pro	Missense	14/27	-
16-68867273-C-T	CDH1	c.2520C>T	p.Ser840Ser	Synonymous	16/16	-
13-32907259-G-A	BRCA2	c.1644G>A	p.Gln548Gln	Synonymous	10/27	-
16-68835787-G-T	CDH1	c.378G>T	p.Pro126Pro	Synonymous	3/16	-
13-32910619-G-A	BRCA2	c.2127G>A	p.Leu709Leu	Synonymous	11/27	-
16-68835787-G-A	CDH1	c.378G>A	p.Pro126Pro	Synonymous	3/16	-
13-32910619-G-C	BRCA2	c.2127G>C	p.Leu709Leu	Synonymous	11/27	-
17-41247881-A-G	BRCA1	c.652T>C	p.Leu218Leu	Synonymous	9/23	-
16-68847248-C-T	CDH1	c.1170C>T	p.Asn390Asn	Synonymous	9/16	-
13-32930634-G-T	BRCA2	c.7505G>T	p.Arg2502Leu	Missense	15/27	-
13-32930634-G-C	BRCA2	c.7505G>C	p.Arg2502Pro	Missense	15/27	-
17-29684080-A-G	NF1	c.7778A>G	p.Lys2593Arg	Missense	52/57	-
11-108137906-C-T	ATM	c.2475C>T	p.Phe825Phe	Synonymous	17/63	-
17-29654537-A-G	NF1	c.5226A>G	p.Gln1742Gln	Synonymous	37/57	-
17-7573948-C-A	TP53	c.1079G>T	p.Gly360Val	Missense	10/11	-
17-29684077-C-T	NF1	c.7775C>T	p.Pro2592Leu	Missense	52/57	-
13-32929232-A-G	BRCA2	c.7242A>G	p.Ser2414Ser	Synonymous	14/27	-
17-29556255-G-A	NF1	c.2622G>A	p.Lys874Lys	Synonymous	21/57	-
13-32969018-C-T	BRCA2	c.9449C>T	p.Pro3150Leu	Missense	25/27	-
19-1220645-G-T	STK11	c.663G>T	p.Pro221Pro	Synonymous	5/10	-
17-7576655-G-A	TP53	c.993+198C>T	-	IntronicSNV	-	9/10
19-1221319-C-T	STK11	c.842C>T	p.Pro281Leu	Missense	6/10	-
17-41215947-C-T	BRCA1	c.5096G>A	p.Arg1699Gln	Missense	17/23	-
22-29091781-C-T	CHEK2	c.1305G>A	p.Ala435Ala	Synonymous	12/16	-
19-1226627-C-T	STK11	c.1283C>T	p.Ser428Leu	Missense	9/10	-
19-1220645-G-A	STK11	c.663G>A	p.Pro221Pro	Synonymous	5/10	-
17-41243015-G-A	BRCA1	c.4131C>T	p.Ser1377Ser	Synonymous	11/23	-
13-32906980-A-G	BRCA2	c.1365A>G	p.Ser455Ser	Synonymous	10/27	-
16-68862130-C-G	CDH1	c.2218C>G	p.Pro740Ala	Missense	14/16	-
16-68862130-C-T	CDH1	c.2218C>T	p.Pro740Ser	Missense	14/16	-
17-7579579-C-T	TP53	c.108G>A	p.Pro36Pro	Synonymous	4/11	-
22-29091846-G-A	CHEK2	c.1240C>T	p.His414Tyr	Missense	12/16	-
17-29585418-C-G	NF1	c.4167C>G	p.Phe1389Leu	Missense	31/57	-
13-32914137-C-G	BRCA2	c.5645C>G	p.Ser1882*	Nonsense	11/27	-
13-32914137-C-A	BRCA2	c.5645C>A	p.Ser1882*	Nonsense	11/27	-
13-32911304-AGCAA-A	BRCA2	c.2812_2815delGCAA	p.Ala938Profs*21	Frameshift	11/27	-
19-1221319-C-A	STK11	c.842C>A	p.Pro281Gln	Missense	6/10	-
17-41215947-C-A	BRCA1	c.5096G>T	p.Arg1699Leu	Missense	17/23	-
17-41215947-C-G	BRCA1	c.5096G>C	p.Arg1699Pro	Missense	17/23	-
22-29091781-C-A	CHEK2	c.1305G>T	p.Ala435Ala	Synonymous	12/16	-
22-29091754-A-G	CHEK2	c.1332T>C	p.Thr444Thr	Synonymous	12/16	-
17-41243015-G-T	BRCA1	c.4131C>A	p.Ser1377Arg	Missense	11/23	-
17-41243696-G-A	BRCA1	c.3852C>T	p.His1284His	Synonymous	10/23	-
13-32914468-A-G	BRCA2	c.5976A>G	p.Ser1992Ser	Synonymous	11/27	-
17-7579882-C-T	TP53	c.31G>A	p.Glu11Lys	Missense	2/11	-
13-32912212-G-A	BRCA2	c.3720G>A	p.Leu1240Leu	Synonymous	11/27	-
22-29090054-G-A	CHEK2	c.1556C>T	p.Thr519Met	Missense	14/16	-
13-32954042-C-T	BRCA2	c.9109C>T	p.Gln3037*	Nonsense	23/27	-
16-23646942-T-C	PALB2	c.925A>G	p.Ile309Val	Missense	4/13	-
11-108142018-A-G	ATM	c.2962A>G	p.Lys988Glu	Missense	20/63	-
13-32954042-C-A	BRCA2	c.9109C>A	p.Gln3037Lys	Missense	23/27	-
11-108170543-T-C	ATM	c.5108T>C	p.Phe1703Ser	Missense	34/63	-
16-23614909-G-A	PALB2	c.3432C>T	p.Leu1144Leu	Synonymous	13/13	-
16-23614909-G-C	PALB2	c.3432C>G	p.Leu1144Leu	Synonymous	13/13	-
19-1221319-C-G	STK11	c.842C>G	p.Pro281Arg	Missense	6/10	-
16-68856122-G-C	CDH1	c.1930G>C	p.Asp644His	Missense	12/16	-
16-68867247-G-C	CDH1	c.2494G>C	p.Val832Leu	Missense	16/16	-
16-68867247-G-A	CDH1	c.2494G>A	p.Val832Met	Missense	16/16	-
16-23646410-T-A	PALB2	c.1457A>T	p.Lys486Ile	Missense	4/13	-
22-29121000-T-C	CHEK2	c.686A>G	p.Asn229Ser	Missense	5/16	-
16-68856122-G-A	CDH1	c.1930G>A	p.Asp644Asn	Missense	12/16	-
17-41244435-T-C	BRCA1	c.3113A>G	p.Glu1038Gly	Missense	10/23	-
11-108178644-T-C	ATM	c.5695T>C	p.Cys1899Arg	Missense	38/63	-
13-32906579-A-C	BRCA2	c.964A>C	p.Lys322Gln	Missense	10/27	-
11-108214071-T-C	ATM	c.8391T>C	p.Ser2797Ser	Synonymous	57/63	-
10-89720797-A-G	PTEN	c.948A>G	p.Leu316Leu	Synonymous	8/9	-
19-1226538-G-A	STK11	c.1194G>A	p.Ala398Ala	Synonymous	9/10	-
13-32953617-G-C	BRCA2	c.8918G>C	p.Arg2973Pro	Missense	22/27	-
22-29083920-T-C	CHEK2	c.1726A>G	p.Thr576Ala	Missense	16/16	-
22-29083920-T-A	CHEK2	c.1726A>T	p.Thr576Ser	Missense	16/16	-
19-1226627-C-A	STK11	c.1283C>A	p.Ser428*	Nonsense	9/10	-
13-32914521-T-G	BRCA2	c.6029T>G	p.Val2010Gly	Missense	11/27	-
17-41223179-G-A	BRCA1	c.4752C>T	p.Ala1584Ala	Synonymous	15/23	-
17-41215920-G-C	BRCA1	c.5123C>G	p.Ala1708Gly	Missense	17/23	-
17-41215920-G-A	BRCA1	c.5123C>T	p.Ala1708Val	Missense	17/23	-
17-41201211-T-C	BRCA1	c.5333A>G	p.Asp1778Gly	Missense	21/23	-
17-41244936-G-A	BRCA1	c.2612C>T	p.Pro871Leu	Missense	10/23	-
17-41244936-G-C	BRCA1	c.2612C>G	p.Pro871Arg	Missense	10/23	-
17-7579484-T-C	TP53	c.203A>G	p.Glu68Gly	Missense	4/11	-
22-29130426-C-G	CHEK2	c.284G>C	p.Arg95Pro	Missense	2/16	-
22-29091133-C-G	CHEK2	c.1486G>C	p.Ala496Pro	Missense	13/16	-
17-41276070-A-G	BRCA1	c.44T>C	p.Ile15Thr	Missense	2/23	-
17-41246512-G-A	BRCA1	c.1036C>T	p.Pro346Ser	Missense	10/23	-
16-23641186-C-G	PALB2	c.2289G>C	p.Leu763Phe	Missense	5/13	-
13-32944627-C-A	BRCA2	c.8420C>A	p.Ser2807*	Nonsense	19/27	-
13-32944627-C-T	BRCA2	c.8420C>T	p.Ser2807Leu	Missense	19/27	-
17-29562685-A-T	NF1	c.3765A>T	p.Gln1255His	Missense	28/57	-
17-29562685-A-G	NF1	c.3765A>G	p.Gln1255Gln	Synonymous	28/57	-
16-23641520-C-T	PALB2	c.1955G>A	p.Ser652Asn	Missense	5/13	-
17-41215920-G-T	BRCA1	c.5123C>A	p.Ala1708Glu	Missense	17/23	-
11-108154985-G-A	ATM	c.3778G>A	p.Val1260Met	Missense	26/63	-
11-108153474-G-A	ATM	c.3614G>A	p.Arg1205His	Missense	25/63	-
13-32910444-A-G	BRCA2	c.1952A>G	p.Asp651Gly	Missense	11/27	-
17-41244936-G-T	BRCA1	c.2612C>A	p.Pro871Gln	Missense	10/23	-
13-32911593-T-C	BRCA2	c.3101T>C	p.Ile1034Thr	Missense	11/27	-
13-32907262-G-A	BRCA2	c.1647G>A	p.Lys549Lys	Synonymous	10/27	-
16-23647149-G-T	PALB2	c.718C>A	p.Pro240Thr	Missense	4/13	-
22-29083962-G-C	CHEK2	c.1684C>G	p.Arg562Gly	Missense	16/16	-
22-29083962-G-A	CHEK2	c.1684C>T	p.Arg562*	Nonsense	16/16	-
16-68853296-C-G	CDH1	c.1679C>G	p.Thr560Arg	Missense	11/16	-
16-68853296-C-T	CDH1	c.1679C>T	p.Thr560Met	Missense	11/16	-
17-41203135-C-G	BRCA1	c.5278-1G>C	-	IntronicSNV	-	19/22
16-23640969-C-T	PALB2	c.2506G>A	p.Val836Ile	Missense	5/13	-
16-23640969-C-A	PALB2	c.2506G>T	p.Val836Phe	Missense	5/13	-
11-108127004-C-T	ATM	c.2187C>T	p.Tyr729Tyr	Synonymous	14/63	-
22-29130426-C-T	CHEK2	c.284G>A	p.Arg95Gln	Missense	2/16	-
13-32915106-T-G	BRCA2	c.6614T>G	p.Val2205Gly	Missense	11/27	-
17-41203135-C-T	BRCA1	c.5278-1G>A	-	IntronicSNV	-	19/22
17-41203135-C-A	BRCA1	c.5278-1G>T	-	IntronicSNV	-	19/22
17-29663850-G-T	NF1	c.6282G>T	p.Pro2094Pro	Synonymous	41/57	-
11-108206666-A-G	ATM	c.8246A>G	p.Lys2749Arg	Missense	56/63	-
11-108206666-A-T	ATM	c.8246A>T	p.Lys2749Ile	Missense	56/63	-
16-23640969-C-G	PALB2	c.2506G>C	p.Val836Leu	Missense	5/13	-
17-29684090-G-T	NF1	c.7788G>T	p.Ala2596Ala	Synonymous	52/57	-
17-41244748-G-A	BRCA1	c.2800C>T	p.Gln934*	Nonsense	10/23	-
17-29546036-A-C	NF1	c.1541A>C	p.Gln514Pro	Missense	14/57	-
11-108160457-T-A	ATM	c.4365T>A	p.Ser1455Arg	Missense	29/63	-
17-41234580-T-C	BRCA1	c.4198A>G	p.Met1400Val	Missense	12/23	-
13-32905069-A-G	BRCA2	c.695A>G	p.Tyr232Cys	Missense	9/27	-
11-108175550-G-A	ATM	c.5645G>A	p.Arg1882Gln	Missense	37/63	-
17-41244000-T-A	BRCA1	c.3548A>T	p.Lys1183Ile	Missense	10/23	-
17-41244000-T-C	BRCA1	c.3548A>G	p.Lys1183Arg	Missense	10/23	-
13-32900706-G-A	BRCA2	c.587G>A	p.Ser196Asn	Missense	7/27	-
17-41249284-G-A	BRCA1	c.570C>T	p.Thr190Thr	Synonymous	8/23	-
11-108168053-A-C	ATM	c.4949A>C	p.Asn1650Thr	Missense	33/63	-
17-7579542-C-G	TP53	c.145G>C	p.Asp49His	Missense	4/11	-
13-32914277-A-G	BRCA2	c.5785A>G	p.Ile1929Val	Missense	11/27	-
13-32910701-G-T	BRCA2	c.2209G>T	p.Ala737Ser	Missense	11/27	-
11-108200946-C-G	ATM	c.7313C>G	p.Thr2438Arg	Missense	50/63	-
11-108200946-C-T	ATM	c.7313C>T	p.Thr2438Ile	Missense	50/63	-
17-29483084-A-G	NF1	c.144A>G	p.Lys48Lys	Synonymous	2/57	-
17-7576655-G-T	TP53	c.993+198C>A	-	IntronicSNV	-	9/10
17-41243841-T-C	BRCA1	c.3707A>G	p.Asn1236Ser	Missense	10/23	-
17-7579542-C-T	TP53	c.145G>A	p.Asp49Asn	Missense	4/11	-
11-108126944-T-G	ATM	c.2127T>G	p.Ile709Met	Missense	14/63	-
16-68849662-C-A	CDH1	c.1565C>A	p.Thr522Lys	Missense	10/16	-
13-32911312-A-G	BRCA2	c.2820A>G	p.Gln940Gln	Synonymous	11/27	-
16-68849598-G-T	CDH1	c.1501G>T	p.Val501Leu	Missense	10/16	-
16-68849598-G-A	CDH1	c.1501G>A	p.Val501Met	Missense	10/16	-
19-1226601-C-T	STK11	c.1257C>T	p.Ser419Ser	Synonymous	9/10	-
17-7578262-C-G	TP53	c.587G>C	p.Arg196Pro	Missense	6/11	-
19-1226601-C-G	STK11	c.1257C>G	p.Ser419Ser	Synonymous	9/10	-
17-7578262-C-A	TP53	c.587G>T	p.Arg196Leu	Missense	6/11	-
17-29528168-A-G	NF1	c.1176A>G	p.Gln392Gln	Synonymous	10/57	-
11-108121543-C-T	ATM	c.1351C>T	p.Arg451Cys	Missense	10/63	-
19-1220708-G-A	STK11	c.726G>A	p.Gly242Gly	Synonymous	5/10	-
13-32914725-G-T	BRCA2	c.6233G>T	p.Gly2078Val	Missense	11/27	-
13-32914725-G-A	BRCA2	c.6233G>A	p.Gly2078Glu	Missense	11/27	-
13-32914200-T-C	BRCA2	c.5708T>C	p.Ile1903Thr	Missense	11/27	-
17-29676161-A-G	NF1	c.7150A>G	p.Ile2384Val	Missense	48/57	-
17-29585418-C-T	NF1	c.4167C>T	p.Phe1389Phe	Synonymous	31/57	-
16-68853202-A-C	CDH1	c.1585A>C	p.Thr529Pro	Missense	11/16	-
13-32929232-A-T	BRCA2	c.7242A>T	p.Ser2414Ser	Synonymous	14/27	-
17-7579358-C-G	TP53	c.329G>C	p.Arg110Pro	Missense	4/11	-
17-7579358-C-T	TP53	c.329G>A	p.Arg110His	Missense	4/11	-
17-7579358-C-A	TP53	c.329G>T	p.Arg110Leu	Missense	4/11	-
16-68849456-C-T	CDH1	c.1359C>T	p.His453His	Synonymous	10/16	-
19-1223055-G-A	STK11	c.992G>A	p.Arg331Gln	Missense	8/10	-
17-41244617-T-C	BRCA1	c.2931A>G	p.Pro977Pro	Synonymous	10/23	-
13-32910953-G-A	BRCA2	c.2461G>A	p.Val821Ile	Missense	11/27	-
13-32910718-A-G	BRCA2	c.2226A>G	p.Gln742Gln	Synonymous	11/27	-
17-29556180-A-C	NF1	c.2547A>C	p.Gly849Gly	Synonymous	21/57	-
13-32972853-G-C	BRCA2	c.10203G>C	p.Thr3401Thr	Synonymous	27/27	-
16-68857445-G-A	CDH1	c.2080G>A	p.Val694Ile	Missense	13/16	-
17-41245390-C-A	BRCA1	c.2158G>T	p.Glu720*	Nonsense	10/23	-
17-7579705-C-T	TP53	c.91G>A	p.Val31Ile	Missense	3/11	-
16-68862165-C-A	CDH1	c.2253C>A	p.Asn751Lys	Missense	14/16	-
11-108224583-C-A	ATM	c.8762C>A	p.Thr2921Lys	Missense	60/63	-
16-68835753-C-T	CDH1	c.344C>T	p.Thr115Met	Missense	3/16	-
17-7579706-G-A	TP53	c.90C>T	p.Asn30Asn	Synonymous	3/11	-
17-41219701-G-C	BRCA1	c.4998C>G	p.Tyr1666*	Nonsense	16/23	-
13-32906957-C-T	BRCA2	c.1342C>T	p.Arg448Cys	Missense	10/27	-
13-32906957-C-A	BRCA2	c.1342C>A	p.Arg448Ser	Missense	10/27	-
13-32912868-A-G	BRCA2	c.4376A>G	p.Asn1459Ser	Missense	11/27	-
16-23646645-A-G	PALB2	c.1222T>C	p.Tyr408His	Missense	4/13	-
16-23646645-A-C	PALB2	c.1222T>G	p.Tyr408Asp	Missense	4/13	-
10-89720749-C-T	PTEN	c.900C>T	p.Ile300Ile	Synonymous	8/9	-
11-108121767-G-C	ATM	c.1575G>C	p.Lys525Asn	Missense	10/63	-
17-29490284-C-T	NF1	c.369C>T	p.Thr123Thr	Synonymous	4/57	-
13-32914174-C-A	BRCA2	c.5682C>A	p.Tyr1894*	Nonsense	11/27	-
13-32930633-C-T	BRCA2	c.7504C>T	p.Arg2502Cys	Missense	15/27	-
19-1219380-G-A	STK11	c.432G>A	p.Pro144Pro	Synonymous	3/10	-
16-68863641-G-A	CDH1	c.2380G>A	p.Val794Ile	Missense	15/16	-
17-7579366-G-A	TP53	c.321C>T	p.Tyr107Tyr	Synonymous	4/11	-
17-41222946-A-G	BRCA1	c.4985T>C	p.Phe1662Ser	Missense	15/23	-
17-41222946-A-C	BRCA1	c.4985T>G	p.Phe1662Cys	Missense	15/23	-
11-108216581-A-G	ATM	c.8530A>G	p.Ile2844Val	Missense	58/63	-
17-29546048-C-A	NF1	c.1553C>A	p.Thr518Asn	Missense	14/57	-
17-29546048-C-T	NF1	c.1553C>T	p.Thr518Ile	Missense	14/57	-
13-32900670-T-C	BRCA2	c.551T>C	p.Leu184Pro	Missense	7/27	-
11-108098524-C-T	ATM	c.94C>T	p.Arg32Cys	Missense	3/63	-
13-32911841-A-G	BRCA2	c.3349A>G	p.Ile1117Val	Missense	11/27	-
13-32906859-A-G	BRCA2	c.1244A>G	p.His415Arg	Missense	10/27	-
16-23646911-G-T	PALB2	c.956C>A	p.Ser319Tyr	Missense	4/13	-
13-32906648-A-G	BRCA2	c.1033A>G	p.Lys345Glu	Missense	10/27	-
17-41209095-G-A	BRCA1	c.5251C>T	p.Arg1751*	Nonsense	19/23	-
13-32972884-A-G	BRCA2	c.10234A>G	p.Ile3412Val	Missense	27/27	-
17-41245021-T-C	BRCA1	c.2527A>G	p.Thr843Ala	Missense	10/23	-
13-32954037-A-G	BRCA2	c.9104A>G	p.Tyr3035Cys	Missense	23/27	-
11-108200991-G-C	ATM	c.7358G>C	p.Arg2453Pro	Missense	50/63	-
13-32900639-C-T	BRCA2	c.520C>T	p.Arg174Cys	Missense	7/27	-
13-32912737-G-A	BRCA2	c.4245G>A	p.Glu1415Glu	Synonymous	11/27	-
17-41226540-T-A	BRCA1	c.4485-2A>T	-	IntronicSNV	-	13/22
16-68835623-G-C	CDH1	c.214G>C	p.Asp72His	Missense	3/16	-
16-68835623-G-A	CDH1	c.214G>A	p.Asp72Asn	Missense	3/16	-
11-108196142-A-G	ATM	c.6678A>G	p.Leu2226Leu	Synonymous	46/63	-
13-32937526-G-A	BRCA2	c.8187G>A	p.Lys2729Lys	Synonymous	18/27	-
13-32937438-T-C	BRCA2	c.8099T>C	p.Ile2700Thr	Missense	18/27	-
13-32913027-G-A	BRCA2	c.4535G>A	p.Arg1512His	Missense	11/27	-
13-32912402-A-G	BRCA2	c.3910A>G	p.Thr1304Ala	Missense	11/27	-
11-108122704-A-C	ATM	c.1748A>C	p.Tyr583Ser	Missense	11/63	-
11-108122704-A-T	ATM	c.1748A>T	p.Tyr583Phe	Missense	11/63	-
13-32929423-T-TT	BRCA2	c.7433_7433dup	-	SpliceDonorInsertion	14/27	-
22-29121000-T-A	CHEK2	c.686A>T	p.Asn229Ile	Missense	5/16	-
22-29121000-T-G	CHEK2	c.686A>C	p.Asn229Thr	Missense	5/16	-
17-29679351-G-A	NF1	c.7471G>A	p.Gly2491Ser	Missense	50/57	-
13-32900252-A-G	BRCA2	c.440A>G	p.Gln147Arg	Missense	5/27	-
13-32900252-A-T	BRCA2	c.440A>T	p.Gln147Leu	Missense	5/27	-
17-41201179-C-G	BRCA1	c.5365G>C	p.Ala1789Pro	Missense	21/23	-
17-41201179-C-A	BRCA1	c.5365G>T	p.Ala1789Ser	Missense	21/23	-
19-1223126-G-A	STK11	c.1063G>A	p.Asp355Asn	Missense	8/10	-
11-108123629-G-A	ATM	c.1888G>A	p.Val630Met	Missense	12/63	-
16-68842700-A-G	CDH1	c.636A>G	p.Gly212Gly	Synonymous	5/16	-
11-108123628-C-T	ATM	c.1887C>T	p.Ser629Ser	Synonymous	12/63	-
17-41201179-C-T	BRCA1	c.5365G>A	p.Ala1789Thr	Missense	21/23	-
16-68867258-T-C	CDH1	c.2505T>C	p.Tyr835Tyr	Synonymous	16/16	-
13-32915263-C-G	BRCA2	c.6771C>G	p.Pro2257Pro	Synonymous	11/27	-
11-108206607-A-G	ATM	c.8187A>G	p.Gln2729Gln	Synonymous	56/63	-
11-108186743-G-A	ATM	c.6101G>A	p.Arg2034Gln	Missense	42/63	-
13-32906673-C-A	BRCA2	c.1058C>A	p.Ser353*	Nonsense	10/27	-
13-32906673-C-G	BRCA2	c.1058C>G	p.Ser353*	Nonsense	10/27	-
11-108236132-G-T	ATM	c.9068G>T	p.Gly3023Val	Missense	63/63	-
11-108198440-G-A	ATM	c.7044G>A	p.Thr2348Thr	Synonymous	48/63	-
17-29576014-A-G	NF1	c.3987A>G	p.Ser1329Ser	Synonymous	30/57	-
13-32914245-A-G	BRCA2	c.5753A>G	p.His1918Arg	Missense	11/27	-
11-108202221-A-T	ATM	c.7566A>T	p.Gln2522His	Missense	51/63	-
13-32915315-G-A	BRCA2	c.6823G>A	p.Glu2275Lys	Missense	11/27	-
11-108172386-G-A	ATM	c.5189G>A	p.Arg1730Gln	Missense	35/63	-
17-7578244-C-T	TP53	c.605G>A	p.Arg202His	Missense	6/11	-
17-29490282-A-G	NF1	c.367A>G	p.Thr123Ala	Missense	4/57	-
11-108201100-C-T	ATM	c.7467C>T	p.Ser2489Ser	Synonymous	50/63	-
17-29679367-G-C	NF1	c.7487G>C	p.Arg2496Pro	Missense	50/57	-
17-29679367-G-A	NF1	c.7487G>A	p.Arg2496Gln	Missense	50/57	-
11-108186756-C-G	ATM	c.6114C>G	p.His2038Gln	Missense	42/63	-
11-108186756-C-A	ATM	c.6114C>A	p.His2038Gln	Missense	42/63	-
13-32930609-C-T	BRCA2	c.7480C>T	p.Arg2494*	Nonsense	15/27	-
13-32930609-C-A	BRCA2	c.7480C>A	p.Arg2494Arg	Synonymous	15/27	-
11-108121562-G-A	ATM	c.1370G>A	p.Arg457Gln	Missense	10/63	-
17-41243886-T-G	BRCA1	c.3662A>C	p.Glu1221Ala	Missense	10/23	-
19-1223090-G-A	STK11	c.1027G>A	p.Asp343Asn	Missense	8/10	-
11-108141831-C-T	ATM	c.2879C>T	p.Pro960Leu	Missense	19/63	-
11-108141831-C-A	ATM	c.2879C>A	p.Pro960His	Missense	19/63	-
17-7574029-C-T	TP53	c.998G>A	p.Arg333His	Missense	10/11	-
11-108172386-G-T	ATM	c.5189G>T	p.Arg1730Leu	Missense	35/63	-
19-1223150-A-G	STK11	c.1087A>G	p.Thr363Ala	Missense	8/10	-
16-23641057-C-T	PALB2	c.2418G>A	p.Pro806Pro	Synonymous	5/13	-
22-29130651-T-C	CHEK2	c.59A>G	p.Gln20Arg	Missense	2/16	-
13-32913920-G-A	BRCA2	c.5428G>A	p.Val1810Ile	Missense	11/27	-
10-89711873-A-C	PTEN	c.493-2A>C	-	IntronicSNV	-	5/8
10-89711873-A-T	PTEN	c.493-2A>T	-	IntronicSNV	-	5/8
17-29483121-A-G	NF1	c.181A>G	p.Ile61Val	Missense	2/57	-
17-29663850-G-A	NF1	c.6282G>A	p.Pro2094Pro	Synonymous	41/57	-
22-29130426-C-A	CHEK2	c.284G>T	p.Arg95Leu	Missense	2/16	-
17-29657368-C-T	NF1	c.5601C>T	p.Ile1867Ile	Synonymous	38/57	-
10-89711995-A-G	PTEN	c.613A>G	p.Met205Val	Missense	6/9	-
13-32893435-G-T	BRCA2	c.289G>T	p.Glu97*	Nonsense	3/27	-
16-68849662-C-T	CDH1	c.1565C>T	p.Thr522Ile	Missense	10/16	-
17-41256190-G-C	BRCA1	c.390C>G	p.Tyr130*	Nonsense	6/23	-
13-32968951-C-T	BRCA2	c.9382C>T	p.Arg3128*	Nonsense	25/27	-
17-41256190-G-T	BRCA1	c.390C>A	p.Tyr130*	Nonsense	6/23	-
17-7579473-G-T	TP53	c.214C>A	p.Pro72Thr	Missense	4/11	-
13-32972853-G-A	BRCA2	c.10203G>A	p.Thr3401Thr	Synonymous	27/27	-
11-108192097-C-T	ATM	c.6522C>T	p.Ser2174Ser	Synonymous	45/63	-
17-7579473-G-A	TP53	c.214C>T	p.Pro72Ser	Missense	4/11	-
17-7579473-G-C	TP53	c.214C>G	p.Pro72Ala	Missense	4/11	-
17-41246512-G-C	BRCA1	c.1036C>G	p.Pro346Ala	Missense	10/23	-
17-41256190-G-A	BRCA1	c.390C>T	p.Tyr130Tyr	Synonymous	6/23	-
17-41197775-C-A	BRCA1	c.5512G>T	p.Val1838Leu	Missense	23/23	-
17-41197775-C-T	BRCA1	c.5512G>A	p.Val1838Met	Missense	23/23	-
13-32907054-G-A	BRCA2	c.1439G>A	p.Cys480Tyr	Missense	10/27	-
17-7579558-C-G	TP53	c.129G>C	p.Leu43Phe	Missense	4/11	-
19-1226588-G-C	STK11	c.1244G>C	p.Arg415Pro	Missense	9/10	-
19-1226588-G-A	STK11	c.1244G>A	p.Arg415His	Missense	9/10	-
16-68847302-G-A	CDH1	c.1224G>A	p.Ala408Ala	Synonymous	9/16	-
16-23641408-C-T	PALB2	c.2067G>A	p.Ser689Ser	Synonymous	5/13	-
13-32937362-A-G	BRCA2	c.8023A>G	p.Ile2675Val	Missense	18/27	-
16-68847302-G-T	CDH1	c.1224G>T	p.Ala408Ala	Synonymous	9/16	-
17-41223133-A-G	BRCA1	c.4798T>C	p.Leu1600Leu	Synonymous	15/23	-
17-41256182-C-T	BRCA1	c.398G>A	p.Arg133His	Missense	6/23	-
13-32914127-G-T	BRCA2	c.5635G>T	p.Glu1879*	Nonsense	11/27	-
13-32914127-G-A	BRCA2	c.5635G>A	p.Glu1879Lys	Missense	11/27	-
11-108188136-G-A	ATM	c.6235G>A	p.Val2079Ile	Missense	43/63	-
11-108126976-G-A	ATM	c.2159G>A	p.Arg720His	Missense	14/63	-
19-1207037-G-T	STK11	c.125G>T	p.Arg42Leu	Missense	1/10	-
16-68853202-A-G	CDH1	c.1585A>G	p.Thr529Ala	Missense	11/16	-
16-23641408-C-A	PALB2	c.2067G>T	p.Ser689Ser	Synonymous	5/13	-
17-29557278-G-A	NF1	c.2991G>A	p.Arg997Arg	Synonymous	23/57	-
19-1219347-G-T	STK11	c.399G>T	p.Val133Val	Synonymous	3/10	-
11-108224608-G-A	ATM	c.8786+1G>A	-	IntronicSNV	-	60/62
11-108117809-C-A	ATM	c.1020C>A	p.Ala340Ala	Synonymous	8/63	-
17-41244935-C-A	BRCA1	c.2613G>T	p.Pro871Pro	Synonymous	10/23	-
13-32899248-C-T	BRCA2	c.352C>T	p.Arg118Cys	Missense	4/27	-
17-41231356-A-G	BRCA1	c.4358-2725T>C	-	IntronicSNV	-	12/22
13-32914007-G-A	BRCA2	c.5515G>A	p.Val1839Ile	Missense	11/27	-
17-29552151-C-T	NF1	c.1884C>T	p.Tyr628Tyr	Synonymous	17/57	-
11-108098424-G-A	ATM	c.72+1G>A	-	IntronicSNV	-	2/62
11-108098424-G-T	ATM	c.72+1G>T	-	IntronicSNV	-	2/62
17-41243501-C-A	BRCA1	c.4047G>T	p.Thr1349Thr	Synonymous	10/23	-
13-32913870-A-G	BRCA2	c.5378A>G	p.Asn1793Ser	Missense	11/27	-
11-108224608-G-T	ATM	c.8786+1G>T	-	IntronicSNV	-	60/62
17-41244935-C-T	BRCA1	c.2613G>A	p.Pro871Pro	Synonymous	10/23	-
16-68867356-G-A	CDH1	c.2603G>A	p.Arg868His	Missense	16/16	-
17-41244612-C-T	BRCA1	c.2936G>A	p.Arg979His	Missense	10/23	-
11-108224608-G-C	ATM	c.8786+1G>C	-	IntronicSNV	-	60/62
16-68844102-C-T	CDH1	c.690C>T	p.Leu230Leu	Synonymous	6/16	-
16-68844102-C-G	CDH1	c.690C>G	p.Leu230Leu	Synonymous	6/16	-
11-108170523-T-C	ATM	c.5088T>C	p.Tyr1696Tyr	Synonymous	34/63	-
13-32972525-C-A	BRCA2	c.9875C>A	p.Pro3292Gln	Missense	27/27	-
10-89720772-G-A	PTEN	c.923G>A	p.Arg308His	Missense	8/9	-
13-32912475-G-C	BRCA2	c.3983G>C	p.Ser1328Thr	Missense	11/27	-
13-32912475-G-A	BRCA2	c.3983G>A	p.Ser1328Asn	Missense	11/27	-
16-23646594-C-T	PALB2	c.1273G>A	p.Val425Met	Missense	4/13	-
22-29121232-CC-C	CHEK2	c.573+1delG	-	IntronicDeletion	4/16	-
19-1223108-G-A	STK11	c.1045G>A	p.Glu349Lys	Missense	8/10	-
13-32911603-A-G	BRCA2	c.3111A>G	p.Gln1037Gln	Synonymous	11/27	-
11-108137925-C-G	ATM	c.2494C>G	p.Arg832Gly	Missense	17/63	-
19-1207037-G-A	STK11	c.125G>A	p.Arg42Gln	Missense	1/10	-
16-68867391-G-A	CDH1	c.2638G>A	p.Glu880Lys	Missense	16/16	-
11-108142115-C-A	ATM	c.3059C>A	p.Thr1020Lys	Missense	20/63	-
17-41244405-C-G	BRCA1	c.3143G>C	p.Gly1048Ala	Missense	10/23	-
11-108139269-G-A	ATM	c.2771G>A	p.Arg924Gln	Missense	18/63	-
11-108121562-G-T	ATM	c.1370G>T	p.Arg457Leu	Missense	10/63	-
11-108172385-C-G	ATM	c.5188C>G	p.Arg1730Gly	Missense	35/63	-
16-23637698-G-T	PALB2	c.2607C>A	p.Ser869Ser	Synonymous	7/13	-
17-29562787-C-T	NF1	c.3867C>T	p.Phe1289Phe	Synonymous	28/57	-
17-29562787-C-G	NF1	c.3867C>G	p.Phe1289Leu	Missense	28/57	-
16-68855985-G-A	CDH1	c.1793G>A	p.Arg598Gln	Missense	12/16	-
13-32893253-C-A	BRCA2	c.107C>A	p.Ser36Tyr	Missense	3/27	-
11-108186563-A-G	ATM	c.6020A>G	p.Glu2007Gly	Missense	41/63	-
11-108186563-A-C	ATM	c.6020A>C	p.Glu2007Ala	Missense	41/63	-
13-32912687-T-C	BRCA2	c.4195T>C	p.Cys1399Arg	Missense	11/27	-
17-41246305-C-A	BRCA1	c.1243G>T	p.Val415Phe	Missense	10/23	-
16-68867204-G-A	CDH1	c.2451G>A	p.Ala817Ala	Synonymous	16/16	-
11-108127037-A-G	ATM	c.2220A>G	p.Ala740Ala	Synonymous	14/63	-
11-108106476-C-T	ATM	c.411C>T	p.Tyr137Tyr	Synonymous	5/63	-
17-41203102-C-T	BRCA1	c.5310G>A	p.Gly1770Gly	Synonymous	20/23	-
17-41203102-C-G	BRCA1	c.5310G>C	p.Gly1770Gly	Synonymous	20/23	-
17-41245236-A-G	BRCA1	c.2312T>C	p.Leu771Ser	Missense	10/23	-
17-29677303-C-T	NF1	c.7361C>T	p.Thr2454Ile	Missense	49/57	-
17-41246305-C-T	BRCA1	c.1243G>A	p.Val415Ile	Missense	10/23	-
17-29528456-A-G	NF1	c.1213A>G	p.Thr405Ala	Missense	11/57	-
10-89692880-A-G	PTEN	c.364A>G	p.Ile122Val	Missense	5/9	-
22-29083955-C-T	CHEK2	c.1691G>A	p.Arg564Gln	Missense	16/16	-
17-29559778-G-A	NF1	c.3375G>A	p.Ala1125Ala	Synonymous	26/57	-
17-29559778-G-T	NF1	c.3375G>T	p.Ala1125Ala	Synonymous	26/57	-
17-7579470-C-T	TP53	c.217G>A	p.Val73Met	Missense	4/11	-
17-41244405-C-A	BRCA1	c.3143G>T	p.Gly1048Val	Missense	10/23	-
13-32905082-T-C	BRCA2	c.708T>C	p.His236His	Synonymous	9/27	-
17-29483074-A-G	NF1	c.134A>G	p.Asn45Ser	Missense	2/57	-
11-108117809-C-T	ATM	c.1020C>T	p.Ala340Ala	Synonymous	8/63	-
17-41276094-C-T	BRCA1	c.20G>A	p.Arg7His	Missense	2/23	-
17-7579366-G-T	TP53	c.321C>A	p.Tyr107*	Nonsense	4/11	-
22-29130638-G-A	CHEK2	c.72C>T	p.Ser24Ser	Synonymous	2/16	-
11-108139183-A-G	ATM	c.2685A>G	p.Leu895Leu	Synonymous	18/63	-
17-41243908-C-T	BRCA1	c.3640G>A	p.Glu1214Lys	Missense	10/23	-
17-29677202-T-G	NF1	c.7260T>G	p.Ala2420Ala	Synonymous	49/57	-
13-32914461-A-C	BRCA2	c.5969A>C	p.Asp1990Ala	Missense	11/27	-
13-32899248-C-A	BRCA2	c.352C>A	p.Arg118Ser	Missense	4/27	-
17-41247917-G-C	BRCA1	c.616C>G	p.Gln206Glu	Missense	9/23	-
17-41219631-T-A	BRCA1	c.5068A>T	p.Lys1690*	Nonsense	16/23	-
11-108153473-C-T	ATM	c.3613C>T	p.Arg1205Cys	Missense	25/63	-
11-108192129-T-C	ATM	c.6554T>C	p.Ile2185Thr	Missense	45/63	-
17-41245618-A-T	BRCA1	c.1930T>A	p.Cys644Ser	Missense	10/23	-
13-32899279-A-G	BRCA2	c.383A>G	p.Asp128Gly	Missense	4/27	-
10-89685308-A-G	PTEN	c.203A>G	p.Tyr68Cys	Missense	3/9	-
13-32945130-G-A	BRCA2	c.8525G>A	p.Arg2842His	Missense	20/27	-
13-32893271-A-G	BRCA2	c.125A>G	p.Tyr42Cys	Missense	3/27	-
13-32929401-A-G	BRCA2	c.7411A>G	p.Thr2471Ala	Missense	14/27	-
17-41226540-T-C	BRCA1	c.4485-2A>G	-	IntronicSNV	-	13/22
22-29130458-T-C	CHEK2	c.252A>G	p.Glu84Glu	Synonymous	2/16	-
17-7577121-G-C	TP53	c.817C>G	p.Arg273Gly	Missense	8/11	-
17-7577121-G-T	TP53	c.817C>A	p.Arg273Ser	Missense	8/11	-
17-29592288-C-T	NF1	c.4703C>T	p.Thr1568Met	Missense	35/57	-
16-23641217-C-T	PALB2	c.2258G>A	p.Arg753Gln	Missense	5/13	-
17-7576654-G-C	TP53	c.993+199C>G	-	IntronicSNV	-	9/10
17-41249283-C-T	BRCA1	c.571G>A	p.Val191Ile	Missense	8/23	-
11-108192078-C-T	ATM	c.6503C>T	p.Ser2168Leu	Missense	45/63	-
11-108163487-C-T	ATM	c.4578C>T	p.Pro1526Pro	Synonymous	30/63	-
11-108192078-C-G	ATM	c.6503C>G	p.Ser2168Trp	Missense	45/63	-
13-32893361-A-G	BRCA2	c.215A>G	p.Asn72Ser	Missense	3/27	-
13-32914068-ATTAA-A	BRCA2	c.5576_5579delTTAA	p.Ile1859Lysfs*3	Frameshift	11/27	-
13-32929297-A-G	BRCA2	c.7307A>G	p.Asn2436Ser	Missense	14/27	-
10-89717698-T-C	PTEN	c.723T>C	p.Phe241Phe	Synonymous	7/9	-
17-41247907-G-A	BRCA1	c.626C>T	p.Pro209Leu	Missense	9/23	-
13-32912150-T-C	BRCA2	c.3658T>C	p.Tyr1220His	Missense	11/27	-
17-29657472-C-T	NF1	c.5705C>T	p.Thr1902Met	Missense	38/57	-
17-7577548-C-G	TP53	c.733G>C	p.Gly245Arg	Missense	7/11	-
17-41243573-C-T	BRCA1	c.3975G>A	p.Arg1325Arg	Synonymous	10/23	-
11-108164101-C-T	ATM	c.4673C>T	p.Thr1558Met	Missense	31/63	-
16-23619278-C-T	PALB2	c.3257G>A	p.Arg1086Gln	Missense	12/13	-
11-108204681-A-C	ATM	c.7996A>C	p.Thr2666Pro	Missense	54/63	-
17-41246737-C-A	BRCA1	c.811G>T	p.Val271Leu	Missense	10/23	-
13-32906977-A-G	BRCA2	c.1362A>G	p.Lys454Lys	Synonymous	10/27	-
11-108204681-A-G	ATM	c.7996A>G	p.Thr2666Ala	Missense	54/63	-
17-41245201-T-C	BRCA1	c.2347A>G	p.Ile783Val	Missense	10/23	-
16-68847374-C-T	CDH1	c.1296C>T	p.Asn432Asn	Synonymous	9/16	-
17-41223048-A-G	BRCA1	c.4883T>C	p.Met1628Thr	Missense	15/23	-
13-32968839-C-G	BRCA2	c.9270C>G	p.Phe3090Leu	Missense	25/27	-
13-32968839-C-T	BRCA2	c.9270C>T	p.Phe3090Phe	Synonymous	25/27	-
13-32914206-A-T	BRCA2	c.5714A>T	p.His1905Leu	Missense	11/27	-
13-32911463-A-G	BRCA2	c.2971A>G	p.Asn991Asp	Missense	11/27	-
16-68862138-G-A	CDH1	c.2226G>A	p.Leu742Leu	Synonymous	14/16	-
22-29130427-G-C	CHEK2	c.283C>G	p.Arg95Gly	Missense	2/16	-
22-29130427-G-A	CHEK2	c.283C>T	p.Arg95*	Nonsense	2/16	-
17-29559864-A-G	NF1	c.3461A>G	p.Asn1154Ser	Missense	26/57	-
17-29559864-A-T	NF1	c.3461A>T	p.Asn1154Ile	Missense	26/57	-
11-108160359-T-C	ATM	c.4267T>C	p.Cys1423Arg	Missense	29/63	-
13-32906833-C-T	BRCA2	c.1218C>T	p.Ala406Ala	Synonymous	10/27	-
13-32912812-A-C	BRCA2	c.4320A>C	p.Lys1440Asn	Missense	11/27	-
17-41243501-C-T	BRCA1	c.4047G>A	p.Thr1349Thr	Synonymous	10/23	-
13-32906833-C-G	BRCA2	c.1218C>G	p.Ala406Ala	Synonymous	10/27	-
16-68867382-G-A	CDH1	c.2629G>A	p.Gly877Arg	Missense	16/16	-
17-41222975-C-T	BRCA1	c.4956G>A	p.Met1652Ile	Missense	15/23	-
22-29121019-G-A	CHEK2	c.667C>T	p.Arg223Cys	Missense	5/16	-
17-7578406-C-A	TP53	c.524G>T	p.Arg175Leu	Missense	5/11	-
11-108099994-A-C	ATM	c.275A>C	p.Lys92Thr	Missense	4/63	-
17-29508775-G-T	NF1	c.702G>T	p.Leu234Leu	Synonymous	7/57	-
11-108173629-A-G	ATM	c.5369A>G	p.Asp1790Gly	Missense	36/63	-
11-108173629-A-T	ATM	c.5369A>T	p.Asp1790Val	Missense	36/63	-
17-29701104-C-T	NF1	c.8388C>T	p.Ser2796Ser	Synonymous	57/57	-
17-29586143-C-T	NF1	c.4363C>T	p.Arg1455Cys	Missense	32/57	-
13-32912670-C-G	BRCA2	c.4178C>G	p.Ala1393Gly	Missense	11/27	-
11-108192057-G-A	ATM	c.6482G>A	p.Arg2161His	Missense	45/63	-
13-32912670-C-T	BRCA2	c.4178C>T	p.Ala1393Val	Missense	11/27	-
17-7577538-C-A	TP53	c.743G>T	p.Arg248Leu	Missense	7/11	-
19-1220473-C-T	STK11	c.566C>T	p.Thr189Ile	Missense	4/10	-
17-41209095-G-T	BRCA1	c.5251C>A	p.Arg1751Arg	Synonymous	19/23	-
17-7577538-C-G	TP53	c.743G>C	p.Arg248Pro	Missense	7/11	-
16-68844171-C-A	CDH1	c.759C>A	p.Thr253Thr	Synonymous	6/16	-
16-68844171-C-T	CDH1	c.759C>T	p.Thr253Thr	Synonymous	6/16	-
16-68844171-C-G	CDH1	c.759C>G	p.Thr253Thr	Synonymous	6/16	-
13-32912553-C-T	BRCA2	c.4061C>T	p.Thr1354Met	Missense	11/27	-
16-68835678-G-A	CDH1	c.269G>A	p.Arg90Gln	Missense	3/16	-
11-108141873-C-G	ATM	c.2921C>G	p.Ser974Cys	Missense	19/63	-
11-108141873-C-A	ATM	c.2921C>A	p.Ser974Tyr	Missense	19/63	-
11-108141873-C-T	ATM	c.2921C>T	p.Ser974Phe	Missense	19/63	-
17-41219701-G-A	BRCA1	c.4998C>T	p.Tyr1666Tyr	Synonymous	16/23	-
13-32906626-C-T	BRCA2	c.1011C>T	p.Asn337Asn	Synonymous	10/27	-
16-68857343-G-A	CDH1	c.1978G>A	p.Val660Met	Missense	13/16	-
17-29552200-A-G	NF1	c.1933A>G	p.Met645Val	Missense	17/57	-
22-29085152-A-T	CHEK2	c.1642T>A	p.Ser548Thr	Missense	15/16	-
22-29083950-G-A	CHEK2	c.1696C>T	p.Arg566Cys	Missense	16/16	-
17-29657433-C-T	NF1	c.5666C>T	p.Ser1889Phe	Missense	38/57	-
11-108139302-C-A	ATM	c.2804C>A	p.Thr935Lys	Missense	18/63	-
16-23646488-T-C	PALB2	c.1379A>G	p.Gln460Arg	Missense	4/13	-
17-29585395-G-T	NF1	c.4144G>T	p.Gly1382Cys	Missense	31/57	-
17-29585395-G-A	NF1	c.4144G>A	p.Gly1382Ser	Missense	31/57	-
17-29556373-C-T	NF1	c.2740C>T	p.Arg914Trp	Missense	21/57	-
17-41245466-G-A	BRCA1	c.2082C>T	p.Ser694Ser	Synonymous	10/23	-
11-108139302-C-T	ATM	c.2804C>T	p.Thr935Met	Missense	18/63	-
11-108139302-C-G	ATM	c.2804C>G	p.Thr935Arg	Missense	18/63	-
17-41258471-A-G	BRCA1	c.212+2T>C	-	IntronicSNV	-	4/22
17-41215349-C-G	BRCA1	c.5193+1G>C	-	IntronicSNV	-	18/22
17-41215349-C-A	BRCA1	c.5193+1G>T	-	IntronicSNV	-	18/22
17-41215349-C-T	BRCA1	c.5193+1G>A	-	IntronicSNV	-	18/22
17-41199659-C-T	BRCA1	c.5467+1G>A	-	IntronicSNV	-	22/22
13-32971138-C-T	BRCA2	c.9605C>T	p.Pro3202Leu	Missense	26/27	-
16-23646194-A-C	PALB2	c.1673T>G	p.Ile558Ser	Missense	4/13	-
16-23646192-G-A	PALB2	c.1675C>T	p.Gln559*	Nonsense	4/13	-
13-32954009-C-T	BRCA2	c.9076C>T	p.Gln3026*	Nonsense	23/27	-
13-32906958-G-A	BRCA2	c.1343G>A	p.Arg448His	Missense	10/27	-
11-108155170-G-A	ATM	c.3963G>A	p.Met1321Ile	Missense	26/63	-
13-32911438-A-C	BRCA2	c.2946A>C	p.Ile982Ile	Synonymous	11/27	-
17-29677247-A-G	NF1	c.7305A>G	p.Lys2435Lys	Synonymous	49/57	-
13-32911438-A-G	BRCA2	c.2946A>G	p.Ile982Met	Missense	11/27	-
17-29701168-G-A	NF1	c.8452G>A	p.Val2818Met	Missense	57/57	-
19-1226491-C-T	STK11	c.1147C>T	p.Arg383Cys	Missense	9/10	-
16-68847351-G-A	CDH1	c.1273G>A	p.Val425Ile	Missense	9/16	-
16-68847351-G-C	CDH1	c.1273G>C	p.Val425Leu	Missense	9/16	-
17-29677247-A-T	NF1	c.7305A>T	p.Lys2435Asn	Missense	49/57	-
17-29677247-A-C	NF1	c.7305A>C	p.Lys2435Asn	Missense	49/57	-
16-68847350-C-T	CDH1	c.1272C>T	p.Val424Val	Synonymous	9/16	-
11-108142059-A-G	ATM	c.3003A>G	p.Leu1001Leu	Synonymous	20/63	-
22-29095882-G-A	CHEK2	c.1081C>T	p.Arg361Cys	Missense	10/16	-
17-29661908-T-C	NF1	c.5802T>C	p.Asn1934Asn	Synonymous	39/57	-
11-108142059-A-C	ATM	c.3003A>C	p.Leu1001Leu	Synonymous	20/63	-
19-1207176-C-A	STK11	c.264C>A	p.Ile88Ile	Synonymous	1/10	-
19-1207176-C-T	STK11	c.264C>T	p.Ile88Ile	Synonymous	1/10	-
22-29121230-C-A	CHEK2	c.573+1G>T	-	IntronicSNV	-	4/15
17-29533260-C-T	NF1	c.1263C>T	p.Ser421Ser	Synonymous	12/57	-
22-29121230-C-T	CHEK2	c.573+1G>A	-	IntronicSNV	-	4/15
17-41245067-T-G	BRCA1	c.2481A>C	p.Glu827Asp	Missense	10/23	-
17-41256153-C-G	BRCA1	c.427G>C	p.Glu143Gln	Missense	6/23	-
17-41222989-T-G	BRCA1	c.4942A>C	p.Lys1648Gln	Missense	15/23	-
17-41222989-T-C	BRCA1	c.4942A>G	p.Lys1648Glu	Missense	15/23	-
13-32914477-C-T	BRCA2	c.5985C>T	p.Asn1995Asn	Synonymous	11/27	-
17-41245067-T-C	BRCA1	c.2481A>G	p.Glu827Glu	Synonymous	10/23	-
11-108192097-C-A	ATM	c.6522C>A	p.Ser2174Arg	Missense	45/63	-
16-68867397-G-A	CDH1	c.2644G>A	p.Asp882Asn	Missense	16/16	-
13-32911907-A-C	BRCA2	c.3415A>C	p.Lys1139Gln	Missense	11/27	-
13-32911907-A-G	BRCA2	c.3415A>G	p.Lys1139Glu	Missense	11/27	-
17-29684090-G-A	NF1	c.7788G>A	p.Ala2596Ala	Synonymous	52/57	-
13-32937638-C-T	BRCA2	c.8299C>T	p.Pro2767Ser	Missense	18/27	-
11-108123554-C-T	ATM	c.1813C>T	p.His605Tyr	Missense	12/63	-
13-32893422-A-G	BRCA2	c.276A>G	p.Gln92Gln	Synonymous	3/27	-
17-41243908-C-A	BRCA1	c.3640G>T	p.Glu1214*	Nonsense	10/23	-
13-32929127-A-G	BRCA2	c.7137A>G	p.Gly2379Gly	Synonymous	14/27	-
17-29556923-A-G	NF1	c.2921A>G	p.Asn974Ser	Missense	22/57	-