PMID: 31162291

Targeted ultra-deep sequencing of a South African Bantu-speaking cohort to comprehensively map and characterize common and novel variants in 65 pharmacologically-related genes.

Pharmacogenetics and genomics
S Tshabalala, A Choudhury, N Beeton-Kempen, N Martinson, M Ramsay, D Mancama
2019-09

1899 variants were identified in this publication


Variant ID Gene cDNA Protein Consequence Exon Intron
12-21033767-T-C SLCO1B3 c.1332-22T>C - IntronicSNV - 11/15
3-121631841-G-T SLC15A2 c.429-27G>T - IntronicSNV - 4/21
4-155508627-G-C FGA c.510+37C>G - IntronicSNV - 4/5
7-87179143-A-G ABCB1 c.1554+24T>C - IntronicSNV - 14/28
6-31322206-C-T HLA-B c.*54G>A - IntronicSNV - 7/7
11-62768113-C-T SLC22A8 c.437+79G>A - IntronicSNV - 3/10
3-121634360-A-G SLC15A2 c.620-103A>G - IntronicSNV - 6/21
11-62768113-C-G SLC22A8 c.437+79G>C - IntronicSNV - 3/10
3-121634360-A-T SLC15A2 c.620-103A>T - IntronicSNV - 6/21
6-31324829-G-A HLA-B c.73+34C>T - IntronicSNV - 1/7
1-11810271-C-T AGTRAP c.*22C>T - 3-UTRSNV 5/5 -
1-67519430-C-T SLC35D1 c.203+64G>A - IntronicSNV - 1/11
10-101610565-G-A ABCC2 c.4508+12G>A - IntronicSNV - 31/31
5-156482441-G-A HAVCR1 c.150C>T p.Gly50Gly Synonymous 2/8 -
7-99305350-G-A CYP3A7 c.1416+85C>T - IntronicSNV - 12/12
10-96731788-A-G CYP2C9 c.820-73A>G - IntronicSNV - 5/8
5-101627027-T-C SLCO4C1 c.619+20A>G - IntronicSNV - 2/12
6-31324208-G-A HLA-B c.355C>T p.Leu119Phe Missense 3/8 -
6-31324208-G-T HLA-B c.355C>A p.Leu119Ile Missense 3/8 -
6-43411739-T-C ABCC10 c.2401T>C p.Ser801Pro Missense 9/20 -
6-31324852-C-T HLA-B c.73+11G>A - IntronicSNV - 1/7
10-135345603-G-A CYP2E1 c.488-25G>A - IntronicSNV - 3/8
5-156456862-G-T HAVCR1 c.987-10C>A - IntronicSNV - 7/7
12-21428079-T-G SLCO1A2 c.1675+215A>C - IntronicSNV - 12/13
12-21428079-T-C SLCO1A2 c.1675+215A>G - IntronicSNV - 12/13
22-42464617-G-T NAGA c.17-39C>A - IntronicSNV - 1/8
6-31322205-A-T HLA-B c.*55T>A - IntronicSNV - 7/7
6-31239722-A-T HLA-C c.73+54T>A - IntronicSNV - 1/7
6-31239722-A-C HLA-C c.73+54T>G - IntronicSNV - 1/7
5-156479443-CTT-GTC HAVCR1 c.600_602delinsGAC p.Ser201Thr Missense 3/8 -
1-11806234-C-G AGTRAP c.62+340C>G - IntronicSNV - 2/4
1-11806234-C-T AGTRAP c.62+340C>T - IntronicSNV - 2/4
6-43414943-C-T ABCC10 c.3461-43C>T - IntronicSNV - 14/19
6-43414943-C-A ABCC10 c.3461-43C>A - IntronicSNV - 14/19
19-41350615-G-A CYP2A6 c.1224C>T p.Pro408Pro Synonymous 8/9 -
6-160577200-A-T SLC22A1 c.1598+94A>T - IntronicSNV - 10/10
1-171247858-T-C FMO1 c.485-10T>C - IntronicSNV - 4/8
16-28617413-A-C SULT1A1 c.739T>G p.Phe247Val Missense 7/8 -
6-31237342-G-T HLA-C c.1016-40C>A - IntronicSNV - 5/7
6-31324892-G-T HLA-B c.44C>A p.Ala15Glu Missense 1/8 -
20-61303004-T-C SLCO4A1 c.2026-98T>C - IntronicSNV - 11/11
6-31324184-C-A HLA-B c.379G>T p.Val127Leu Missense 3/8 -
6-31324184-C-T HLA-B c.379G>A p.Val127Met Missense 3/8 -
7-87174066-T-A ABCB1 c.2064+73A>T - IntronicSNV - 17/28
1-171251197-T-C FMO1 c.908T>C p.Ile303Thr Missense 7/9 -
11-62768095-C-G SLC22A8 c.437+97G>C - IntronicSNV - 3/10
1-171083174-C-T FMO3 c.855C>T p.Asn285Asn Synonymous 7/9 -
15-92690451-C-T SLCO3A1 c.1688+62C>T - IntronicSNV - 8/9
6-31239821-G-T HLA-C c.28C>A p.Leu10Ile Missense 1/8 -
6-31239821-G-C HLA-C c.28C>G p.Leu10Val Missense 1/8 -
6-31322175-C-T HLA-B c.*85G>A - IntronicSNV - 7/7
7-87135416-T-C ABCB1 c.3490-57A>G - IntronicSNV - 27/28
6-31237727-T-A HLA-C c.1015+16A>T - IntronicSNV - 5/7
1-171252442-T-C FMO1 c.1256+87T>C - IntronicSNV - 8/8
1-171252442-T-A FMO1 c.1256+87T>A - IntronicSNV - 8/8
1-171252442-T-G FMO1 c.1256+87T>G - IntronicSNV - 8/8
1-97981395-T-C DPYD c.1627A>G p.Ile543Val Missense 13/23 -
10-101559158-A-C ABCC2 c.1031+31A>C - IntronicSNV - 8/31
19-41497293-ACCG-GCAC CYP2B6 c.83_86delinsGCAC p.Asp28_arg29delinsGlythr MultiAAMissense 1/9 -
10-101603522-T-C ABCC2 c.3742-34T>C - IntronicSNV - 26/31
12-21014178-A-G SLCO1B3 c.481+106A>G - IntronicSNV - 6/15
15-90335251-C-T ANPEP c.2528+140G>A - IntronicSNV - 18/20
6-31239802-C-G HLA-C c.47G>C p.Gly16Ala Missense 1/8 -
7-99312240-T-G CYP3A7 c.736A>C p.Ile246Leu Missense 8/13 -
15-90347171-G-C ANPEP c.1242C>G p.Ala414Ala Synonymous 7/21 -
10-96802598-A-T CYP2C8 c.1149+49T>A - IntronicSNV - 7/8
1-171083225-C-T FMO3 c.906C>T p.Asn302Asn Synonymous 7/9 -
7-99312240-T-C CYP3A7 c.736A>G p.Ile246Val Missense 8/13 -
6-31322357-G-T HLA-B c.1045+53C>A - IntronicSNV - 6/7
5-101631986-A-G SLCO4C1 c.1-20T>C - 5-UTRSNV 1/13 -
12-21015205-C-A SLCO1B3 c.482-141C>A - IntronicSNV - 6/15
6-31322357-G-A HLA-B c.1045+53C>T - IntronicSNV - 6/7
1-67487375-C-CAGA SLC35D1 c.730-91_730-90insTCT - IntronicInsertion - 8/11
6-160553066-C-T SLC22A1 c.516-198C>T - IntronicSNV - 2/10
15-92647645-G-C SLCO3A1 c.882G>C p.Glu294Asp Missense 4/10 -
1-67470209-T-C SLC35D1 c.960-78A>G - IntronicSNV - 11/11
4-155531500-A-G FGG c.402-151T>C - IntronicSNV - 4/8
12-21036533-T-C SLCO1B3 c.1679T>C p.Val560Ala Missense 13/16 -
19-41351771-C-A CYP2A6 c.973+90G>T - IntronicSNV - 6/8
6-31323107-G-GG HLA-B c.882dupC p.Thr295Hisfs*39 Frameshift 4/8 -
7-99315314-A-G CYP3A7 c.319-52T>C - IntronicSNV - 4/12
6-31324176-C-G HLA-B c.387G>C p.Pro129Pro Synonymous 3/8 -
7-99250394-A-AA CYP3A5 c.1035_1035dup p.Thr346Tyrfs*3 Frameshift 11/13 -
1-171077165-G-A FMO3 c.485-55G>A - IntronicSNV - 4/8
6-160577063-G-A SLC22A1 c.1555G>A p.Val519Ile Missense 10/11 -
6-160577063-G-T SLC22A1 c.1555G>T p.Val519Phe Missense 10/11 -
15-90333616-T-C ANPEP c.2751+75A>G - IntronicSNV - 20/20
17-61562795-G-A ACE c.2058+62G>A - IntronicSNV - 13/24
11-74904362-T-C SLCO2B1 c.1175T>C p.Ile392Thr Missense 9/14 -
15-90333616-T-G ANPEP c.2751+75A>C - IntronicSNV - 20/20
15-90333616-T-A ANPEP c.2751+75A>T - IntronicSNV - 20/20
22-42456461-G-T NAGA c.1102-44C>A - IntronicSNV - 8/8
1-171227216-T-C FMO1 c.1-11T>C - IntronicSNV - 1/8
3-133654846-G-A SLCO2A1 c.1691-105C>T - IntronicSNV - 12/13
1-11810273-CTGCCCC-CTGCCCCCTGCCCC AGTRAP c.*24_*30dup - 3-UTRInsertion 5/5 -
6-43401105-G-A ABCC10 c.1251+7G>A - IntronicSNV - 1/19
6-43413141-A-G ABCC10 c.2946+89A>G - IntronicSNV - 12/19
6-31237002-G-C HLA-C c.1097-52C>G - IntronicSNV - 7/7
17-61561252-C-T ACE c.1629C>T p.Ala543Ala Synonymous 11/25 -
7-99260362-C-A CYP3A5 c.865+77G>T - IntronicSNV - 9/12
13-95859035-C-G ABCC4 c.912G>C p.Lys304Asn Missense 8/31 -
13-95859035-C-A ABCC4 c.912G>T p.Lys304Asn Missense 8/31 -
13-95859035-C-T ABCC4 c.912G>A p.Lys304Lys Synonymous 8/31 -
20-61299088-C-T SLCO4A1 c.1473-9C>T - IntronicSNV - 7/11
20-61299088-C-A SLCO4A1 c.1473-9C>A - IntronicSNV - 7/11
10-135351362-T-C CYP2E1 c.1263T>C p.Phe421Phe Synonymous 8/9 -
20-61299088-C-G SLCO4A1 c.1473-9C>G - IntronicSNV - 7/11
10-135351362-T-G CYP2E1 c.1263T>G p.Phe421Leu Missense 8/9 -
10-96541538-T-A CYP2C19 c.643-40T>A - IntronicSNV - 4/8
1-97548076-A-G DPYD c.2767-50T>C - IntronicSNV - 21/22
6-31239766-C-T HLA-C c.73+10G>A - IntronicSNV - 1/7
19-41515256-G-A CYP2B6 c.778G>A p.Ala260Thr Missense 5/9 -
3-121659878-C-T SLC15A2 c.*24C>T - 3-UTRSNV 22/22 -
19-41515256-G-T CYP2B6 c.778G>T p.Ala260Ser Missense 5/9 -
10-96534768-G-A CYP2C19 c.169-47G>A - IntronicSNV - 1/8
10-96534768-G-C CYP2C19 c.169-47G>C - IntronicSNV - 1/8
1-97544760-C-G DPYD c.2908-58G>C - IntronicSNV - 22/22
1-98165091-T-C DPYD c.496A>G p.Met166Val Missense 6/23 -
1-110232801-A-G GSTM1 c.361-92A>G - IntronicSNV - 5/7
1-67518534-C-T SLC35D1 c.244G>A p.Ala82Thr Missense 3/12 -
16-28617308-A-G SULT1A1 c.776-54T>C - IntronicSNV - 7/7
11-64338485-G-T SLC22A11 c.1624G>T p.Ala542Ser Missense 10/10 -
20-61288626-T-C SLCO4A1 c.796+24T>C - IntronicSNV - 2/11
20-61288626-T-G SLCO4A1 c.796+24T>G - IntronicSNV - 2/11
2-234676458-T-C UGT1A1 c.997-37T>C - IntronicSNV - 2/4
19-41497286-A-T CYP2B6 c.76A>T p.Thr26Ser Missense 1/9 -
8-18074516-G-A NAT1 c.-85-2404G>A - intron_variant - 1/2
17-61558951-C-T ACE c.970C>T p.Arg324Trp Missense 7/25 -
1-98039437-C-T DPYD c.1218G>A p.Met406Ile Missense 11/23 -
12-21450250-C-G SLCO1A2 c.1075+88G>C - IntronicSNV - 8/13
15-90347331-G-A ANPEP c.1180-98C>T - IntronicSNV - 6/20
12-21450250-C-T SLCO1A2 c.1075+88G>A - IntronicSNV - 8/13
20-61288392-C-G SLCO4A1 c.586C>G p.Arg196Gly Missense 2/12 -
20-61288392-C-T SLCO4A1 c.586C>T p.Arg196Cys Missense 2/12 -
15-75044238-G-A CYP1A2 c.1042+43G>A - IntronicSNV - 4/6
3-121613347-G-A SLC15A2 c.24G>A p.Glu8Glu Synonymous 1/22 -
15-90344722-G-C ANPEP c.1686C>G p.Ser562Ser Synonymous 11/21 -
19-41356123-G-C CYP2A6 c.180+29C>G - IntronicSNV - 1/8
20-61288355-G-T SLCO4A1 c.549G>T p.Gly183Gly Synonymous 2/12 -
20-61288355-G-A SLCO4A1 c.549G>A p.Gly183Gly Synonymous 2/12 -
16-28618058-G-A SULT1A1 c.594+24C>T - IntronicSNV - 6/7
13-95727780-T-A ABCC4 c.2712A>T p.Leu904Phe Missense 22/31 -
3-42915878-C-T CYP8B1 c.1431G>A p.Pro477Pro Synonymous 1/1 -
16-28617552-C-G SULT1A1 c.600G>C p.Pro200Pro Synonymous 7/8 -
16-28617552-C-T SULT1A1 c.600G>A p.Pro200Pro Synonymous 7/8 -
4-89039243-T-C ABCG2 c.841+18A>G - IntronicSNV - 7/15
6-31324887-G-C HLA-B c.49C>G p.Leu17Val Missense 1/8 -
6-31324887-G-T HLA-B c.49C>A p.Leu17Met Missense 1/8 -
1-110231041-T-C GSTM1 c.112+174T>C - IntronicSNV - 2/7
6-31237975-T-C HLA-C c.895+12A>G - IntronicSNV - 4/7
19-41350505-C-A CYP2A6 c.1303+31G>T - IntronicSNV - 8/8
19-41350505-C-G CYP2A6 c.1303+31G>C - IntronicSNV - 8/8
19-41350505-C-T CYP2A6 c.1303+31G>A - IntronicSNV - 8/8
6-31237087-C-T HLA-C c.1096+28G>A - IntronicSNV - 7/7
6-31237087-C-A HLA-C c.1096+28G>T - IntronicSNV - 7/7
12-21355489-C-G SLCO1B1 c.1200C>G p.Phe400Leu Missense 10/15 -
6-160560881-A-G SLC22A1 c.1258A>G p.Met420Val Missense 7/11 -
7-99315276-C-T CYP3A7 c.319-14G>A - IntronicSNV - 4/12
6-160560881-A-T SLC22A1 c.1258A>T p.Met420Leu Missense 7/11 -
12-21453135-C-T SLCO1A2 c.910+147G>A - IntronicSNV - 7/13
5-156456709-C-T HAVCR1 c.*35G>A - 3-UTRSNV 8/8 -
22-25010941-G-A GGT1 c.296-67G>A - IntronicSNV - 6/15
7-87168749-C-G ABCB1 c.2320-88G>C - IntronicSNV - 19/28
12-21459876-T-A SLCO1A2 c.382A>T p.Asn128Tyr Missense 4/14 -
6-31324036-T-G HLA-B c.527A>C p.Glu176Ala Missense 3/8 -
6-31324036-T-A HLA-B c.527A>T p.Glu176Val Missense 3/8 -
5-156479557-G-A HAVCR1 c.488C>T p.Thr163Met Missense 3/8 -
17-61557823-G-T ACE c.781G>T p.Ala261Ser Missense 5/25 -
13-95886854-T-A ABCC4 c.531+10A>T - IntronicSNV - 4/30
13-95886854-T-C ABCC4 c.531+10A>G - IntronicSNV - 4/30
10-96707508-G-A CYP2C9 c.482-28G>A - IntronicSNV - 3/8
12-21467666-A-C SLCO1A2 c.203-51T>G - IntronicSNV - 2/13
4-89042960-T-C ABCG2 c.532-16A>G - IntronicSNV - 5/15
3-119534626-G-A NR1I2 c.1108G>A p.Ala370Thr Missense 8/9 -
13-95859058-A-G ABCC4 c.912-23T>C - IntronicSNV - 7/30
6-31237896-C-A HLA-C c.896-34G>T - IntronicSNV - 4/7
19-41512787-C-G CYP2B6 c.485-23C>G - IntronicSNV - 3/8
17-61556554-G-C ACE c.511+93G>C - IntronicSNV - 3/24
8-18257795-C-T NAT2 c.282C>T p.Tyr94Tyr Synonymous 2/2 -
8-27467984-C-A CLU c.97+8G>T - IntronicSNV - 2/8
8-27467984-C-T CLU c.97+8G>A - IntronicSNV - 2/8
12-21068883-A-T SLCO1B3 c.1866-55A>T - IntronicSNV - 15/15
6-31322996-C-T HLA-B c.900G>A p.Pro300Pro Synonymous 5/8 -
7-87229501-T-A ABCB1 c.1-1A>T - 5-UTRSNV 3/29 -
1-171086122-A-T FMO3 c.1257-118A>T - IntronicSNV - 8/8
10-101576960-T-C ABCC2 c.2095-105T>C - IntronicSNV - 16/31
6-31322980-C-T HLA-B c.916G>A p.Val306Ile Missense 5/8 -
1-67508067-A-G SLC35D1 c.637-56T>C - IntronicSNV - 7/11
4-89016625-T-C ABCG2 c.1737+47A>G - IntronicSNV - 14/15
1-11808597-C-A AGTRAP c.294C>A p.Leu98Leu Synonymous 4/5 -
1-11808597-C-T AGTRAP c.294C>T p.Leu98Leu Synonymous 4/5 -
17-61557823-G-A ACE c.781G>A p.Ala261Thr Missense 5/25 -
6-31237857-A-C HLA-C c.901T>G p.Ser301Ala Missense 5/8 -
7-87135435-T-C ABCB1 c.3490-76A>G - IntronicSNV - 27/28
12-21471891-T-A SLCO1A2 c.61-34A>T - IntronicSNV - 1/13
22-25023302-G-A GGT1 c.1021-97G>A - IntronicSNV - 11/15
10-135342101-G-C CYP2E1 c.294G>C p.Ser98Ser Synonymous 2/9 -
17-61570937-T-C ACE c.3053T>C p.Ile1018Thr Missense 20/25 -
11-62750921-C-T SLC22A6 c.628+88G>A - IntronicSNV - 3/9
7-75614082-C-G POR c.1067-13C>G - IntronicSNV - 10/15
19-41512692-C-T CYP2B6 c.485-118C>T - IntronicSNV - 3/8
22-42462180-C-T NAGA c.598-277G>A - IntronicSNV - 5/8
10-101605607-C-T ABCC2 c.4146+68C>T - IntronicSNV - 29/31
15-90346547-C-G ANPEP c.1504-12G>C - IntronicSNV - 9/20
13-95673939-A-T ABCC4 c.3871-3T>A - IntronicSNV - 30/30
13-95673939-A-G ABCC4 c.3871-3T>C - IntronicSNV - 30/30
15-90346547-C-T ANPEP c.1504-12G>A - IntronicSNV - 9/20
1-97848017-T-G DPYD c.1906A>C p.Ile636Leu Missense 15/23 -
12-21294840-A-G SLCO1B1 c.84+248A>G - IntronicSNV - 2/14
6-31237353-T-C HLA-C c.1016-51A>G - IntronicSNV - 5/7
6-31237353-T-A HLA-C c.1016-51A>T - IntronicSNV - 5/7
1-171154959-A-G FMO2 c.107A>G p.Asp36Gly Missense 2/9 -
12-21487383-A-T SLCO1A2 c.60+139T>A - IntronicSNV - 1/13
6-31238135-G-A HLA-C c.747C>T p.Thr249Thr Synonymous 4/8 -
6-43402149-G-C ABCC10 c.1252-210G>C - IntronicSNV - 1/19
5-101631518-A-C SLCO4C1 c.355+94T>G - IntronicSNV - 1/12
17-61558320-C-T ACE c.848-132C>T - IntronicSNV - 5/24
7-87179926-G-A ABCB1 c.1114-32C>T - IntronicSNV - 11/28
12-21014163-T-A SLCO1B3 c.481+91T>A - IntronicSNV - 6/15
12-21014163-T-G SLCO1B3 c.481+91T>G - IntronicSNV - 6/15
10-96732061-T-C CYP2C9 c.961+59T>C - IntronicSNV - 6/8
6-31322205-A-C HLA-B c.*55T>G - IntronicSNV - 7/7
16-28617298-G-C SULT1A1 c.776-44C>G - IntronicSNV - 7/7
16-28617298-G-A SULT1A1 c.776-44C>T - IntronicSNV - 7/7
19-41356123-G-A CYP2A6 c.180+29C>T - IntronicSNV - 1/8
12-21015526-C-T SLCO1B3 c.628+34C>T - IntronicSNV - 7/15
10-96745935-A-G CYP2C9 c.1291+4A>G - IntronicSNV - 8/8
22-25007132-A-G GGT1 c.84A>G p.Ser28Ser Synonymous 5/16 -
11-62752356-G-A SLC22A6 c.1-194C>T - 5-UTRSNV 1/10 -
6-31324194-G-T HLA-B c.369C>A p.Tyr123* Nonsense 3/8 -
7-87173667-A-T ABCB1 c.2065-76T>A - IntronicSNV - 17/28
5-156482459-G-T HAVCR1 c.132C>A p.Ser44Ser Synonymous 2/8 -
17-61574492-G-C ACE c.3692-6G>C - IntronicSNV - 24/24
12-21036326-G-T SLCO1B3 c.1498-26G>T - IntronicSNV - 12/15
7-99261676-A-G CYP3A5 c.713T>C p.Val238Ala Missense 8/13 -
20-61303252-C-T SLCO4A1 c.*7C>T - 3-UTRSNV 12/12 -
12-21014139-C-G SLCO1B3 c.481+67C>G - IntronicSNV - 6/15
7-99261676-A-T CYP3A5 c.713T>A p.Val238Asp Missense 8/13 -
12-21422492-G-C SLCO1A2 c.2003C>G p.Thr668Ser Missense 14/14 -
11-62747145-A-G SLC22A6 c.1252+61T>C - IntronicSNV - 7/9
17-61566031-G-A ACE c.2328G>A p.Thr776Thr Synonymous 16/25 -
16-28617361-G-A SULT1A1 c.775+16C>T - IntronicSNV - 7/7
4-89015887-T-C ABCG2 c.1738-76A>G - IntronicSNV - 14/15
11-74914479-C-T SLCO2B1 c.1949+7C>T - IntronicSNV - 13/13
6-31323020-T-C HLA-B c.896-20A>G - IntronicSNV - 4/7
10-96741053-A-G CYP2C9 c.1075A>G p.Ile359Val Missense 7/9 -
10-96741053-A-C CYP2C9 c.1075A>C p.Ile359Leu Missense 7/9 -
3-121647286-C-G SLC15A2 c.1225C>G p.Pro409Ala Missense 15/22 -
11-74914479-C-A SLCO2B1 c.1949+7C>A - IntronicSNV - 13/13
19-41356310-G-A CYP2A6 c.22C>T p.Leu8Leu Synonymous 1/9 -
3-119529220-G-A NR1I2 c.331+179G>A - IntronicSNV - 3/8
15-90349191-C-T ANPEP c.614+10G>A - IntronicSNV - 2/20
11-74874979-C-T SLCO2B1 c.148-29C>T - IntronicSNV - 2/13
15-75045692-T-C CYP1A2 c.1253+81T>C - IntronicSNV - 6/6
6-31239752-C-A HLA-C c.73+24G>T - IntronicSNV - 1/7
17-61557939-C-T ACE c.847+50C>T - IntronicSNV - 5/24
6-31239752-C-T HLA-C c.73+24G>A - IntronicSNV - 1/7
11-62749344-G-A SLC22A6 c.767C>T p.Ala256Val Missense 4/10 -
1-97848041-T-G DPYD c.1906-24A>C - IntronicSNV - 14/22
1-11807427-G-A AGTRAP c.63-70G>A - IntronicSNV - 2/4
1-11807427-G-C AGTRAP c.63-70G>C - IntronicSNV - 2/4
17-61566396-C-G ACE c.2544C>G p.Leu848Leu Synonymous 17/25 -
13-95899890-G-A ABCC4 c.185+7C>T - IntronicSNV - 2/30
17-61566396-C-T ACE c.2544C>T p.Leu848Leu Synonymous 17/25 -
10-101579082-T-C ABCC2 c.2620+56T>C - IntronicSNV - 19/31
7-87179695-T-C ABCB1 c.1225-83A>G - IntronicSNV - 12/28
16-28619920-A-G SULT1A1 c.153T>C p.Thr51Thr Synonymous 3/8 -
11-62749494-G-A SLC22A6 c.629-12C>T - IntronicSNV - 3/9
3-121658203-A-C SLC15A2 c.1769A>C p.Asn590Thr Missense 20/22 -
3-121658203-A-G SLC15A2 c.1769A>G p.Asn590Ser Missense 20/22 -
20-61290360-C-T SLCO4A1 c.887+241C>T - IntronicSNV - 3/11
6-31239827-C-G HLA-C c.22G>C p.Ala8Pro Missense 1/8 -
19-41512841-G-T CYP2B6 c.516G>T p.Gln172His Missense 4/9 -
1-67487391-C-G SLC35D1 c.730-106G>C - IntronicSNV - 8/11
22-42459107-C-T NAGA c.760-79G>A - IntronicSNV - 6/8
6-31239827-C-A HLA-C c.22G>T p.Ala8Ser Missense 1/8 -
6-31239827-C-T HLA-C c.22G>A p.Ala8Thr Missense 1/8 -
15-90347783-C-T ANPEP c.963G>A p.Thr321Thr Synonymous 5/21 -
19-41515247-G-A CYP2B6 c.769G>A p.Asp257Asn Missense 5/9 -
7-87138684-G-A ABCB1 c.3396C>T p.Ala1132Ala Synonymous 27/29 -
10-101560169-G-A ABCC2 c.1058G>A p.Arg353His Missense 9/32 -
3-121658376-G-A SLC15A2 c.1908+34G>A - IntronicSNV - 20/21
20-61300457-G-C SLCO4A1 c.2025+27G>C - IntronicSNV - 11/11
10-96740981-C-T CYP2C9 c.1003C>T p.Arg335Trp Missense 7/9 -
17-61558398-G-A ACE c.848-54G>A - IntronicSNV - 5/24
12-21353672-G-A SLCO1B1 c.1135+66G>A - IntronicSNV - 9/14
17-61557689-C-T ACE c.656-9C>T - IntronicSNV - 4/24
19-41351268-G-A CYP2A6 c.1092C>T p.Asp364Asp Synonymous 7/9 -
6-31322888-A-C HLA-B c.1008T>G p.Ser336Arg Missense 5/8 -
12-21051504-A-T SLCO1B3 c.1747+70A>T - IntronicSNV - 14/15
7-99365892-A-C CYP3A4 c.670+85T>G - IntronicSNV - 7/12
17-61561756-A-G ACE c.1775A>G p.Asp592Gly Missense 12/25 -
17-61561756-A-T ACE c.1775A>T p.Asp592Val Missense 12/25 -
15-92647306-G-A SLCO3A1 c.746-203G>A - IntronicSNV - 3/9
15-92647306-G-C SLCO3A1 c.746-203G>C - IntronicSNV - 3/9
3-42916735-T-C CYP8B1 c.574A>G p.Lys192Glu Missense 1/1 -
3-119533910-T-C NR1I2 c.879T>C p.Asn293Asn Synonymous 6/9 -
6-160557515-G-A SLC22A1 c.955-61G>A - IntronicSNV - 5/10
6-31237323-A-G HLA-C c.1016-21T>C - IntronicSNV - 5/7
17-61571630-C-T ACE c.3282-103C>T - IntronicSNV - 21/24
7-87168749-C-T ABCB1 c.2320-88G>A - IntronicSNV - 19/28
3-121647782-C-G SLC15A2 c.1342-47C>G - IntronicSNV - 15/21
6-31322470-C-G HLA-B c.1013-28G>C - IntronicSNV - 5/7
17-61571452-C-T ACE c.3281+25C>T - IntronicSNV - 21/24
13-95860288-C-A ABCC4 c.786-109G>T - IntronicSNV - 6/30
6-31239506-C-G HLA-C c.213G>C p.Pro71Pro Synonymous 2/8 -
3-133748266-G-A SLCO2A1 c.96+285C>T - IntronicSNV - 1/13
3-133748266-G-T SLCO2A1 c.96+285C>A - IntronicSNV - 1/13
3-119526372-G-A NR1I2 c.197+78G>A - IntronicSNV - 2/8
22-25019781-C-G GGT1 c.918C>G p.Pro306Pro Synonymous 11/16 -
3-42916596-T-C CYP8B1 c.713A>G p.Lys238Arg Missense 1/1 -
11-62766431-A-T SLC22A8 c.723T>A p.Thr241Thr Synonymous 5/11 -
9-130914434-A-G LCN2 c.476-28A>G - IntronicSNV - 4/6
7-75614953-T-A POR c.1455T>A p.Ala485Ala Synonymous 13/16 -
1-98293842-T-C DPYD c.151-90A>G - IntronicSNV - 2/22
20-61297564-C-T SLCO4A1 c.1277-168C>T - IntronicSNV - 6/11
20-61296183-G-C SLCO4A1 c.1122-103G>C - IntronicSNV - 5/11
6-31324741-G-A HLA-B c.74-7C>T - IntronicSNV - 1/7
10-96824738-A-G CYP2C8 c.482-21T>C - IntronicSNV - 3/8
1-110232834-G-A GSTM1 c.361-59G>A - IntronicSNV - 5/7
17-61562373-A-G ACE c.1922-224A>G - IntronicSNV - 12/24
6-160551093-T-G SLC22A1 c.412-43T>G - IntronicSNV - 1/10
5-101606071-T-A SLCO4C1 c.802+257A>T - IntronicSNV - 3/12
11-74873659-G-A SLCO2B1 c.17-41G>A - IntronicSNV - 1/13
7-87160561-A-G ABCB1 c.2685+49T>C - IntronicSNV - 22/28
13-95858978-T-C ABCC4 c.969A>G p.Ser323Ser Synonymous 8/31 -
12-21446936-T-C SLCO1A2 c.1380A>G p.Ser460Ser Synonymous 10/14 -
12-21446936-T-A SLCO1A2 c.1380A>T p.Ser460Ser Synonymous 10/14 -
9-130914004-T-C LCN2 c.355+8T>C - IntronicSNV - 3/6
1-110230569-A-G GSTM1 c.36+38A>G - IntronicSNV - 1/7
10-96702066-G-C CYP2C9 c.449G>C p.Arg150Pro Missense 3/9 -
3-133670225-T-C SLCO2A1 c.725-37A>G - IntronicSNV - 5/13
9-130914200-C-T LCN2 c.371C>T p.Thr124Met Missense 4/7 -
15-75041902-G-A CYP1A2 c.1-178G>A - IntronicSNV - 1/6
6-31323958-T-A HLA-B c.605A>T p.Lys202Met Missense 3/8 -
11-62751239-C-T SLC22A6 c.474-76G>A - IntronicSNV - 2/9
7-17379157-G-A AHR c.1708G>A p.Val570Ile Missense 10/11 -
20-61299972-C-T SLCO4A1 c.1876+79C>T - IntronicSNV - 10/11
6-160551203-T-G SLC22A1 c.479T>G p.Leu160Trp Missense 2/11 -
10-96535124-A-G CYP2C19 c.332-23A>G - IntronicSNV - 2/8
10-96702066-G-A CYP2C9 c.449G>A p.Arg150His Missense 3/9 -
10-96702066-G-T CYP2C9 c.449G>T p.Arg150Leu Missense 3/9 -
7-99366047-T-C CYP3A4 c.600A>G p.Gln200Gln Synonymous 7/13 -
22-25023506-G-A GGT1 c.1128G>A p.Pro376Pro Synonymous 12/16 -
4-89022367-C-A ABCG2 c.1367+15G>T - IntronicSNV - 11/15
4-89022367-C-G ABCG2 c.1367+15G>C - IntronicSNV - 11/15
12-21448768-A-G SLCO1A2 c.1076-42T>C - IntronicSNV - 8/13
8-27462481-A-C CLU c.789T>G p.His263Gln Missense 5/9 -
8-27462481-A-G CLU c.789T>C p.His263His Synonymous 5/9 -
10-96827126-A-AA CYP2C8 c.332-6_332-6dup - IntronicInsertion - 2/8
3-133654677-C-T SLCO2A1 c.1755G>A p.Ser585Ser Synonymous 13/14 -
6-160579527-C-T SLC22A1 c.1599-21C>T - IntronicSNV - 10/10
3-133654677-C-A SLCO2A1 c.1755G>T p.Ser585Ser Synonymous 13/14 -
12-21011581-G-A SLCO1B3 c.359+76G>A - IntronicSNV - 5/15
7-99303138-G-A CYP3A7 c.1497C>T p.Thr499Thr Synonymous 13/13 -
6-31324086-G-T HLA-B c.477C>A p.Ala159Ala Synonymous 3/8 -
6-31239577-A-T HLA-C c.142T>A p.Ser48Thr Missense 2/8 -
6-31239577-A-G HLA-C c.142T>C p.Ser48Pro Missense 2/8 -
1-98386300-C-T DPYD c.39+140G>A - IntronicSNV - 1/22
6-31237061-C-T HLA-C c.1096+54G>A - IntronicSNV - 7/7
3-119501581-C-A NR1I2 c.-23+434C>A - intron_variant - 1/8
15-90334240-A-G ANPEP c.2613T>C p.Ile871Ile Synonymous 19/21 -
3-119530546-T-C NR1I2 c.492T>C p.Thr164Thr Synonymous 4/9 -
5-156469808-C-T HAVCR1 c.782-115G>A - IntronicSNV - 4/7
8-27461789-G-C CLU c.934+19C>G - IntronicSNV - 6/8
1-98015121-C-T DPYD c.1519G>A p.Val507Ile Missense 12/23 -
6-31237237-G-A HLA-C c.1048+33C>T - IntronicSNV - 6/7
12-21428246-A-C SLCO1A2 c.1675+48T>G - IntronicSNV - 12/13
12-21317791-C-T SLCO1B1 c.85-7793C>T - IntronicSNV - 2/14
10-101605455-C-T ABCC2 c.4062C>T p.Ala1354Ala Synonymous 29/32 -
5-156479557-G-T HAVCR1 c.488C>A p.Thr163Lys Missense 3/8 -
6-31323116-C-T HLA-B c.873G>A p.Pro291Pro Synonymous 4/8 -
10-96826966-C-G CYP2C8 c.480G>C p.Lys160Asn Missense 3/9 -
3-121659860-C-G SLC15A2 c.*6C>G - 3-UTRSNV 22/22 -
10-96707471-G-C CYP2C9 c.482-65G>C - IntronicSNV - 3/8
6-31236998-C-T HLA-C c.1097-48G>A - IntronicSNV - 7/7
6-31236998-C-G HLA-C c.1097-48G>C - IntronicSNV - 7/7
13-95859058-A-T ABCC4 c.912-23T>A - IntronicSNV - 7/30
7-87180198-C-A ABCB1 c.1000-44G>T - IntronicSNV - 10/28
12-21294784-C-T SLCO1B1 c.84+192C>T - IntronicSNV - 2/14
10-96826966-C-T CYP2C8 c.480G>A p.Lys160Lys Synonymous 3/9 -
10-96580202-C-G CYP2C19 c.820-51C>G - IntronicSNV - 5/8
13-95748312-T-C ABCC4 c.2536-12768A>G - IntronicSNV - 20/30
12-21014126-G-A SLCO1B3 c.481+54G>A - IntronicSNV - 6/15
3-121631841-G-A SLC15A2 c.429-27G>A - IntronicSNV - 4/21
9-130914425-G-A LCN2 c.476-37G>A - IntronicSNV - 4/6
4-155508627-G-A FGA c.510+37C>T - IntronicSNV - 4/5
22-42456271-T-C NAGA c.*12A>G - 3-UTRSNV 9/9 -
13-95829843-G-A ABCC4 c.1727+118C>T - IntronicSNV - 13/30
13-95715147-A-T ABCC4 c.3211-34T>A - IntronicSNV - 25/30
15-90328551-G-A ANPEP c.*29C>T - 3-UTRSNV 21/21 -
13-95818628-T-C ABCC4 c.1825-7A>G - IntronicSNV - 14/30
1-171244541-G-T FMO1 c.378G>T p.Glu126Asp Missense 4/9 -
5-156479469-C-T HAVCR1 c.576G>A p.Thr192Thr Synonymous 3/8 -
1-171244541-G-A FMO1 c.378G>A p.Glu126Glu Synonymous 4/9 -
7-87174066-T-G ABCB1 c.2064+73A>C - IntronicSNV - 17/28
13-95768387-A-C ABCC4 c.2456-132T>G - IntronicSNV - 19/30
9-130913750-G-A LCN2 c.276-167G>A - IntronicSNV - 2/6
7-17379110-G-A AHR c.1661G>A p.Arg554Lys Missense 10/11 -
7-87174066-T-C ABCB1 c.2064+73A>G - IntronicSNV - 17/28
10-96522561-T-C CYP2C19 c.99T>C p.Pro33Pro Synonymous 1/9 -
9-130913798-G-T LCN2 c.276-119G>T - IntronicSNV - 2/6
9-130913798-G-A LCN2 c.276-119G>A - IntronicSNV - 2/6
1-171178152-A-G FMO2 c.1476A>G - synonymous_variant 9/9 -
11-62751658-G-A SLC22A6 c.369+136C>T - IntronicSNV - 1/9
3-133748711-G-C SLCO2A1 c.1-65C>G - 5-UTRSNV 1/14 -
13-95715069-G-T ABCC4 c.3255C>A p.Ile1085Ile Synonymous 26/31 -
1-171083242-A-G FMO3 c.923A>G p.Glu308Gly Missense 7/9 -
6-31324209-G-T HLA-B c.354C>A p.Thr118Thr Synonymous 3/8 -
13-95727780-T-C ABCC4 c.2712A>G p.Leu904Leu Synonymous 22/31 -
8-27464244-T-C CLU c.247-203A>G - IntronicSNV - 3/8
15-90333565-G-A ANPEP c.2751+126C>T - IntronicSNV - 20/20
1-67487256-G-A SLC35D1 c.759C>T p.Thr253Thr Synonymous 9/12 -
6-31324209-G-C HLA-B c.354C>G p.Thr118Thr Synonymous 3/8 -
6-31324209-G-A HLA-B c.354C>T p.Thr118Thr Synonymous 3/8 -
7-87138532-A-G ABCB1 c.3489+59T>C - IntronicSNV - 27/28
22-42456473-C-T NAGA c.1102-56G>A - IntronicSNV - 8/8
5-101597423-A-T SLCO4C1 c.1021+193T>A - IntronicSNV - 5/12
6-31237016-C-T HLA-C c.1097-66G>A - IntronicSNV - 7/7
6-31239449-C-G HLA-C c.270G>C p.Lys90Asn Missense 2/8 -
6-31237124-T-G HLA-C c.1087A>C p.Thr363Pro Missense 7/8 -
13-95714858-A-C ABCC4 c.3366+100T>G - IntronicSNV - 26/30
6-31238029-T-A HLA-C c.853A>T p.Met285Leu Missense 4/8 -
1-171162438-C-T FMO2 c.133-36C>T - IntronicSNV - 2/8
10-96732061-T-A CYP2C9 c.961+59T>A - IntronicSNV - 6/8
6-31324955-C-T HLA-B c.1-20G>A - 5-UTRSNV 1/8 -
19-41355865-G-A CYP2A6 c.201C>T p.Pro67Pro Synonymous 2/9 -
6-31322996-C-G HLA-B c.900G>C p.Pro300Pro Synonymous 5/8 -
6-31237048-A-G HLA-C c.1096+67T>C - IntronicSNV - 7/7
11-74904600-G-A SLCO2B1 c.1413G>A p.Ala471Ala Synonymous 9/14 -
6-31238029-T-G HLA-C c.853A>C p.Met285Leu Missense 4/8 -
7-75613999-G-A POR c.1067-96G>A - IntronicSNV - 10/15
16-66969591-T-G CES2 c.53T>G - missense_variant 1/12 -
17-61560986-A-T ACE c.1586+67A>T - IntronicSNV - 10/24
1-11808413-C-T AGTRAP c.169-59C>T - IntronicSNV - 3/4
12-21008143-A-C SLCO1B3 c.226+40A>C - IntronicSNV - 4/15
17-61561252-C-G ACE c.1629C>G p.Ala543Ala Synonymous 11/25 -
6-43415002-G-A ABCC10 c.3477G>A p.Ser1159Ser Synonymous 15/20 -
12-21011421-A-G SLCO1B3 c.275A>G p.His92Arg Missense 5/16 -
3-121634410-T-A SLC15A2 c.620-53T>A - IntronicSNV - 6/21
13-95847144-C-T ABCC4 c.1209G>A p.Pro403Pro Synonymous 9/31 -
19-41497272-AGC-TGT CYP2B6 c.62_64delinsTGT p.Gln21_arg22delinsLeucys MultiAAMissense 1/9 -
6-31324086-G-C HLA-B c.477C>G p.Ala159Ala Synonymous 3/8 -
6-31324086-G-A HLA-B c.477C>T p.Ala159Ala Synonymous 3/8 -
7-99365913-A-G CYP3A4 c.670+64T>C - IntronicSNV - 7/12
15-75015206-A-G CYP1A1 c.233T>C p.Ile78Thr Missense 2/7 -
10-96824832-C-G CYP2C8 c.482-115G>C - IntronicSNV - 3/8
4-155525486-G-A FGG c.*500C>T - IntergenicSNV 9/9 -
19-41515894-C-T CYP2B6 c.823-5C>T - IntronicSNV - 5/8
19-41515894-C-A CYP2B6 c.823-5C>A - IntronicSNV - 5/8
13-95887098-G-A ABCC4 c.307-10C>T - IntronicSNV - 3/30
15-90328551-G-C ANPEP c.*29C>G - 3-UTRSNV 21/21 -
10-96708974-A-G CYP2C9 c.752A>G p.His251Arg Missense 5/9 -
9-130914425-G-T LCN2 c.476-37G>T - IntronicSNV - 4/6
6-31237257-C-T HLA-C c.1048+13G>A - IntronicSNV - 6/7
6-31324210-G-C HLA-B c.353C>G p.Thr118Ser Missense 3/8 -
10-101591944-T-C ABCC2 c.3258+56T>C - IntronicSNV - 23/31
8-18079654-G-A NAT1 c.98G>A p.Arg33Gln Missense 3/3 -
7-99269397-T-C CYP3A5 c.318+806A>G - IntronicSNV - 4/12
10-96702047-C-T CYP2C9 c.430C>T p.Arg144Cys Missense 3/9 -
5-156482099-TT-TTTT HAVCR1 c.379+113_379+114dup - IntronicInsertion - 2/7
1-110233147-C-T GSTM1 c.528C>T p.Asp176Asp Synonymous 7/8 -
5-101592809-T-A SLCO4C1 c.1469+10A>T - IntronicSNV - 8/12
1-97847874-T-C DPYD c.1974+75A>G - IntronicSNV - 15/22
12-21331499-T-C SLCO1B1 c.482-11T>C - IntronicSNV - 5/14
3-133653566-G-A SLCO2A1 c.1923C>T p.Gly641Gly Synonymous 14/14 -
11-74873858-C-G SLCO2B1 c.147+28C>G - IntronicSNV - 2/13
16-66974146-G-A CES2 c.637G>A p.Gly213Ser Missense 5/12 -
16-66974146-G-C CES2 c.637G>C p.Gly213Arg Missense 5/12 -
15-90342626-G-A ANPEP c.1953+31C>T - IntronicSNV - 13/20
6-160553238-C-T SLC22A1 c.516-26C>T - IntronicSNV - 2/10
1-171077198-G-A FMO3 c.485-22G>A - IntronicSNV - 4/8
20-61289958-G-A SLCO4A1 c.797-71G>A - IntronicSNV - 2/11
17-61571755-C-A ACE c.3304C>A p.Pro1102Thr Missense 22/25 -
15-90333654-A-T ANPEP c.2751+37T>A - IntronicSNV - 20/20
3-133653746-G-A SLCO2A1 c.1815-72C>T - IntronicSNV - 13/13
11-62746840-G-A SLC22A6 c.1361+120C>T - IntronicSNV - 8/9
5-156479424-A-T HAVCR1 c.621T>A p.Thr207Thr Synonymous 3/8 -
6-31239681-A-C HLA-C c.74-36T>G - IntronicSNV - 1/7
3-119536074-G-A NR1I2 c.*15G>A - 3-UTRSNV 9/9 -
20-61287672-G-C SLCO4A1 c.1-135G>C - IntronicSNV - 1/11
12-21294329-T-G SLCO1B1 c.1-180T>G - IntronicSNV - 1/14
22-42464645-C-A NAGA c.17-67G>T - IntronicSNV - 1/8
22-42464645-C-T NAGA c.17-67G>A - IntronicSNV - 1/8
1-171252287-A-C FMO1 c.1188A>C p.Val396Val Synonymous 8/9 -
20-61298966-GC-TG SLCO4A1 c.1473-131_1473-130delinsTG - IntronicBlockSubstitution - 7/11
1-171162583-T-C FMO2 c.242T>C p.Phe81Ser Missense 3/9 -
6-160577011-G-A SLC22A1 c.1503G>A p.Val501Val Synonymous 10/11 -
3-133657211-T-C SLCO2A1 c.1690+62A>G - IntronicSNV - 12/13
13-95696252-C-T ABCC4 c.3630-211G>A - IntronicSNV - 28/30
9-130915488-A-T LCN2 c.*90A>T - IntronicSNV - 6/6
3-121643893-T-A SLC15A2 c.1124+13T>A - IntronicSNV - 13/21
13-95695837-A-T ABCC4 c.3735+99T>A - IntronicSNV - 29/30
20-61288427-G-A SLCO4A1 c.621G>A p.Thr207Thr Synonymous 2/12 -
20-61288427-G-T SLCO4A1 c.621G>T p.Thr207Thr Synonymous 2/12 -
17-61560049-G-C ACE c.1341G>C p.Thr447Thr Synonymous 8/25 -
17-61560049-G-T ACE c.1341G>T p.Thr447Thr Synonymous 8/25 -
17-61560049-G-A ACE c.1341G>A p.Thr447Thr Synonymous 8/25 -
19-41351169-CG-TA CYP2A6 c.1161+29_1161+30delinsTA - IntronicBlockSubstitution - 7/8
6-31324895-G-A HLA-B c.41C>T p.Ser14Leu Missense 1/8 -
15-90333654-A-G ANPEP c.2751+37T>C - IntronicSNV - 20/20
20-61287803-G-A SLCO4A1 c.1-4G>A - 5-UTRSNV 2/12 -
20-61288550-C-T SLCO4A1 c.744C>T p.Gly248Gly Synonymous 2/12 -
7-99270099-C-A CYP3A5 c.318+104G>T - IntronicSNV - 4/12
6-31239306-T-A HLA-C c.343+70A>T - IntronicSNV - 2/7
6-31239306-T-G HLA-C c.343+70A>C - IntronicSNV - 2/7
17-61564443-T-A ACE c.2305+9T>A - IntronicSNV - 15/24
10-101590186-C-A ABCC2 c.2743C>A p.Arg915Ser Missense 20/32 -
20-61288370-G-A SLCO4A1 c.564G>A p.Ala188Ala Synonymous 2/12 -
3-133654649-C-T SLCO2A1 c.1783G>A p.Ala595Thr Missense 13/14 -
3-133654649-C-G SLCO2A1 c.1783G>C p.Ala595Pro Missense 13/14 -
10-101557080-C-G ABCC2 c.859C>G p.Leu287Val Missense 7/32 -
10-101557080-C-T ABCC2 c.859C>T p.Leu287Phe Missense 7/32 -
6-43405665-C-T ABCC10 c.1792-7C>T - IntronicSNV - 4/19
4-89061114-C-T ABCG2 c.34G>A p.Val12Met Missense 2/16 -
19-41351169-C-G CYP2A6 c.1161+30G>C - IntronicSNV - 7/8
19-41351169-C-T CYP2A6 c.1161+30G>A - IntronicSNV - 7/8
19-41356225-C-G CYP2A6 c.107G>C p.Gly36Ala Missense 1/9 -
4-155511861-C-T FGA c.1-22G>A - 5-UTRSNV 1/6 -
4-155511861-C-A FGA c.1-22G>T - 5-UTRSNV 1/6 -
20-61298966-G-T SLCO4A1 c.1473-131G>T - IntronicSNV - 7/11
20-61298966-G-A SLCO4A1 c.1473-131G>A - IntronicSNV - 7/11
11-62752014-C-G SLC22A6 c.149G>C p.Arg50Pro Missense 1/10 -
6-31239855-C-G HLA-C c.1-7G>C - 5-UTRSNV 1/8 -
11-62752014-C-A SLC22A6 c.149G>T p.Arg50Leu Missense 1/10 -
11-62752014-C-T SLC22A6 c.149G>A p.Arg50His Missense 1/10 -
6-31239855-C-T HLA-C c.1-7G>A - 5-UTRSNV 1/8 -
6-31239868-G-C HLA-C c.1-20C>G - 5-UTRSNV 1/8 -
10-101591818-A-G ABCC2 c.3188A>G p.Asn1063Ser Missense 23/32 -
6-160575957-A-C SLC22A1 c.1498+15A>C - IntronicSNV - 9/10
6-31239868-G-T HLA-C c.1-20C>A - 5-UTRSNV 1/8 -
6-31239868-G-A HLA-C c.1-20C>T - 5-UTRSNV 1/8 -
1-67487119-C-A SLC35D1 c.797+99G>T - IntronicSNV - 9/11
6-31322888-A-G HLA-B c.1008T>C p.Ser336Ser Synonymous 5/8 -
3-121650421-C-A SLC15A2 c.1665-65C>A - IntronicSNV - 18/21
21-43735365-G-A TFF3 c.124+38C>T - IntronicSNV - 1/2
5-156479424-A-C HAVCR1 c.621T>G p.Thr207Thr Synonymous 3/8 -
10-101552041-A-G ABCC2 c.258A>G p.Val86Val Synonymous 3/32 -
5-101631526-C-G SLCO4C1 c.355+86G>C - IntronicSNV - 1/12
6-31239417-C-A HLA-C c.302G>T p.Ser101Ile Missense 2/8 -
6-31239417-C-T HLA-C c.302G>A p.Ser101Asn Missense 2/8 -
3-133748334-T-A SLCO2A1 c.96+217A>T - IntronicSNV - 1/13
10-96827178-T-C CYP2C8 c.332-64A>G - IntronicSNV - 2/8
20-61287879-G-C SLCO4A1 c.73G>C p.Asp25His Missense 2/12 -
1-11807696-C-T AGTRAP c.168+94C>T - IntronicSNV - 3/4
22-25023302-G-T GGT1 c.1021-97G>T - IntronicSNV - 11/15
7-87178882-A-C ABCB1 c.1555-48T>G - IntronicSNV - 14/28
7-87178882-A-G ABCB1 c.1555-48T>C - IntronicSNV - 14/28
7-87190625-T-C ABCB1 c.781A>G p.Ile261Val Missense 9/29 -
6-31239681-A-T HLA-C c.74-36T>A - IntronicSNV - 1/7
1-171250044-C-T FMO1 c.747C>T p.Thr249Thr Synonymous 6/9 -
22-25010967-G-T GGT1 c.296-41G>T - IntronicSNV - 6/15
22-25010967-G-C GGT1 c.296-41G>C - IntronicSNV - 6/15
22-25010967-G-A GGT1 c.296-41G>A - IntronicSNV - 6/15
6-32557435-A-C HLA-DRB1 c.85T>G p.Ser29Ala Missense 1/6 -
9-130913608-G-T LCN2 c.276-309G>T - IntronicSNV - 2/6
6-31237275-G-A HLA-C c.1043C>T p.Ala348Val Missense 6/8 -
16-66977997-A-G CES2 c.*69A>G - 3-UTRSNV 12/12 -
9-130913608-G-C LCN2 c.276-309G>C - IntronicSNV - 2/6
17-61556527-A-T ACE c.511+66A>T - IntronicSNV - 3/24
22-42461731-C-T NAGA c.759+11G>A - IntronicSNV - 6/8
20-61292536-C-T SLCO4A1 c.1121+9C>T - IntronicSNV - 5/11
19-41351959-A-C CYP2A6 c.875T>G p.Val292Gly Missense 6/9 -
1-171247794-C-T FMO1 c.485-74C>T - IntronicSNV - 4/8
8-18074536-G-A NAT1 c.-85-2384G>A - intron_variant - 1/2
10-101595975-G-T ABCC2 c.3542G>T p.Arg1181Leu Missense 25/32 -
19-41518773-C-T CYP2B6 c.1294+53C>T - IntronicSNV - 8/8
3-121643752-A-G SLC15A2 c.1036-40A>G - IntronicSNV - 12/21
13-95726541-A-G ABCC4 c.2844T>C p.Phe948Phe Synonymous 23/31 -
10-96748701-C-T CYP2C9 c.1389C>T p.Asp463Asp Synonymous 9/9 -
19-41497274-C-T CYP2B6 c.64C>T p.Arg22Cys Missense 1/9 -
6-43412935-T-C ABCC10 c.2829T>C p.Tyr943Tyr Synonymous 12/20 -
22-42456874-C-G NAGA c.1101+54G>C - IntronicSNV - 8/8
6-31237233-A-G HLA-C c.1048+37T>C - IntronicSNV - 6/7
10-101604207-C-G ABCC2 c.3972C>G p.Ile1324Met Missense 28/32 -
10-101604207-C-T ABCC2 c.3972C>T p.Ile1324Ile Synonymous 28/32 -
10-101595996-T-A ABCC2 c.3563T>A p.Val1188Glu Missense 25/32 -
12-21327740-C-A SLCO1B1 c.359+97C>A - IntronicSNV - 4/14
6-31323184-C-T HLA-B c.805G>A p.Ala269Thr Missense 4/8 -
3-119529113-G-T NR1I2 c.331+72G>T - IntronicSNV - 3/8
5-156479464-G-T HAVCR1 c.581C>A p.Thr194Lys Missense 3/8 -
5-156479464-G-A HAVCR1 c.581C>T p.Thr194Met Missense 3/8 -
3-133666209-C-T SLCO2A1 c.1186G>A p.Ala396Thr Missense 9/14 -
3-133666209-C-G SLCO2A1 c.1186G>C p.Ala396Pro Missense 9/14 -
13-95862896-A-G ABCC4 c.621+50T>C - IntronicSNV - 5/30
1-171252287-A-G FMO1 c.1188A>G p.Val396Val Synonymous 8/9 -
13-95862896-A-C ABCC4 c.621+50T>G - IntronicSNV - 5/30
6-31322220-C-T HLA-B c.*40G>A - IntronicSNV - 7/7
19-41356316-T-G CYP2A6 c.16A>C p.Met6Leu Missense 1/9 -
1-110233247-T-C GSTM1 c.567+61T>C - IntronicSNV - 7/7
10-135342101-G-A CYP2E1 c.294G>A p.Ser98Ser Synonymous 2/9 -
20-61290000-C-T SLCO4A1 c.797-29C>T - IntronicSNV - 2/11
20-61290000-C-A SLCO4A1 c.797-29C>A - IntronicSNV - 2/11
10-96827125-AA-AAAA CYP2C8 c.332-7_332-6dup - IntronicInsertion - 2/8
22-25016737-A-G GGT1 c.576-143A>G - IntronicSNV - 8/15
1-171254448-C-A FMO1 c.1364C>A p.Thr455Lys Missense 9/9 -
1-171254448-C-T FMO1 c.1364C>T p.Thr455Met Missense 9/9 -
20-61291686-C-T SLCO4A1 c.888-78C>T - IntronicSNV - 3/11
15-90342657-C-T ANPEP c.1953G>A p.Ser651Ser Synonymous 13/21 -
15-90342657-C-A ANPEP c.1953G>T p.Ser651Ser Synonymous 13/21 -
2-234669148-C-T UGT1A1 c.215C>T p.Ala72Val Missense 1/5 -
7-99303094-G-A CYP3A7 c.*29C>T - 3-UTRSNV 13/13 -
6-31324085-C-T HLA-B c.478G>A p.Ala160Thr Missense 3/8 -
3-42916511-C-A CYP8B1 c.798G>T p.Gly266Gly Synonymous 1/1 -
15-90328558-G-A ANPEP c.*22C>T - 3-UTRSNV 21/21 -
4-155525373-G-A FGG c.*613C>T - IntergenicSNV 9/9 -
15-90328558-G-C ANPEP c.*22C>G - 3-UTRSNV 21/21 -
10-135352356-A-T CYP2E1 c.1370A>T p.His457Leu Missense 9/9 -
7-99361466-C-T CYP3A4 c.1023+12G>A - IntronicSNV - 10/12
7-99367867-C-G CYP3A4 c.319-9G>C - IntronicSNV - 4/12
6-31323885-G-T HLA-B c.619+59C>A - IntronicSNV - 3/7
5-156482099-TTA-CTT HAVCR1 c.379+111_379+113delinsAAG - IntronicBlockSubstitution - 2/7
8-18258279-A-T NAT2 c.766A>T p.Lys256* Nonsense 2/2 -
1-171085315-T-C FMO3 c.1184-33T>C - IntronicSNV - 7/8
6-31239776-A-G HLA-C c.73T>C p.Cys25Arg Missense 1/8 -
6-31239776-A-C HLA-C c.73T>G p.Cys25Gly Missense 1/8 -
16-28619911-T-A SULT1A1 c.162A>T p.Val54Val Synonymous 3/8 -
6-32557435-A-T HLA-DRB1 c.85T>A p.Ser29Thr Missense 1/6 -
22-42456461-G-A NAGA c.1102-44C>T - IntronicSNV - 8/8
6-160560933-C-T SLC22A1 c.1276+34C>T - IntronicSNV - 7/10
11-62750858-T-C SLC22A6 c.628+151A>G - IntronicSNV - 3/9
11-74907721-C-A SLCO2B1 c.1596C>A p.Ser532Arg Missense 10/14 -
11-74907721-C-T SLCO2B1 c.1596C>T p.Ser532Ser Synonymous 10/14 -
16-28619911-T-C SULT1A1 c.162A>G p.Val54Val Synonymous 3/8 -
16-28619911-T-G SULT1A1 c.162A>C p.Val54Val Synonymous 3/8 -
12-21015243-C-T SLCO1B3 c.482-103C>T - IntronicSNV - 6/15
1-171251268-T-C FMO1 c.979T>C p.Phe327Leu Missense 7/9 -
11-64329587-C-T SLC22A11 c.609C>T p.Ala203Ala Synonymous 3/10 -
12-21015243-C-A SLCO1B3 c.482-103C>A - IntronicSNV - 6/15
6-160575715-T-C SLC22A1 c.1386-115T>C - IntronicSNV - 8/10
10-96824883-T-C CYP2C8 c.482-166A>G - IntronicSNV - 3/8
6-31324077-C-T HLA-B c.486G>A p.Thr162Thr Synonymous 3/8 -
15-75045684-A-G CYP1A2 c.1253+73A>G - IntronicSNV - 6/6
9-130914211-G-A LCN2 c.382G>A p.Val128Ile Missense 4/7 -
9-130914211-G-C LCN2 c.382G>C p.Val128Leu Missense 4/7 -
7-99270299-C-T CYP3A5 c.222G>A p.Thr74Thr Synonymous 4/13 -
20-61287669-G-A SLCO4A1 c.1-138G>A - IntronicSNV - 1/11
6-31322395-A-C HLA-B c.1045+15T>G - IntronicSNV - 6/7
1-97658679-A-G DPYD c.2568T>C p.Thr856Thr Synonymous 20/23 -
15-90347338-T-C ANPEP c.1180-105A>G - IntronicSNV - 6/20
22-42464614-G-A NAGA c.17-36C>T - IntronicSNV - 1/8
11-64335218-C-A SLC22A11 c.1206C>A p.Arg402Arg Synonymous 7/10 -
13-95695837-A-C ABCC4 c.3735+99T>G - IntronicSNV - 29/30
15-92397350-C-T SLCO3A1 c.180+32C>T - IntronicSNV - 1/9
6-31323945-A-C HLA-B c.618T>G p.Ala206Ala Synonymous 3/8 -
5-101572807-C-A SLCO4C1 c.2015-85G>T - IntronicSNV - 12/12
11-74862356-T-C SLCO2B1 c.1-71T>C - 5-UTRSNV 1/14 -
6-31323945-A-G HLA-B c.618T>C p.Ala206Ala Synonymous 3/8 -
6-31237896-C-G HLA-C c.896-34G>C - IntronicSNV - 4/7
11-112020916-T-G IL18 c.105A>C p.Ser35Ser Synonymous 4/6 -
11-112020916-T-A IL18 c.105A>T p.Ser35Ser Synonymous 4/6 -
6-31322220-C-G HLA-B c.*40G>C - IntronicSNV - 7/7
5-101574885-A-G SLCO4C1 c.2014+70T>C - IntronicSNV - 12/12
12-21331963-A-G SLCO1B1 c.727+9A>G - IntronicSNV - 7/14
12-21331963-A-C SLCO1B1 c.727+9A>C - IntronicSNV - 7/14
10-96701939-T-A CYP2C9 c.332-10T>A - IntronicSNV - 2/8
4-89039434-A-C ABCG2 c.690-22T>G - IntronicSNV - 6/15
15-90349461-G-A ANPEP c.354C>T p.Asp118Asp Synonymous 2/21 -
12-21459722-A-G SLCO1A2 c.442+94T>C - IntronicSNV - 4/13
12-21329813-C-T SLCO1B1 c.463C>T p.Pro155Ser Missense 5/15 -
10-96702007-G-T CYP2C9 c.390G>T p.Thr130Thr Synonymous 3/9 -
5-101575091-C-T SLCO4C1 c.1878G>A p.Gly626Gly Synonymous 12/13 -
10-135352509-T-C CYP2E1 c.*41T>C - 3-UTRSNV 9/9 -
10-135352509-T-A CYP2E1 c.*41T>A - 3-UTRSNV 9/9 -
11-64323877-C-G SLC22A11 c.393+13C>G - IntronicSNV - 1/9
11-64323877-C-A SLC22A11 c.393+13C>A - IntronicSNV - 1/9
9-130914182-C-A LCN2 c.356-3C>A - IntronicSNV - 3/6
16-28620030-G-C SULT1A1 c.147C>G p.Ser49Ser Synonymous 2/8 -
20-61297955-C-T SLCO4A1 c.1472+28C>T - IntronicSNV - 7/11
6-31237991-G-T HLA-C c.891C>A p.Ser297Arg Missense 4/8 -
15-90334345-C-G ANPEP c.2529-21G>C - IntronicSNV - 18/20
13-95858996-T-A ABCC4 c.951A>T p.Arg317Ser Missense 8/31 -
13-95858996-T-C ABCC4 c.951A>G p.Arg317Arg Synonymous 8/31 -
6-31323945-A-T HLA-B c.618T>A p.Ala206Ala Synonymous 3/8 -
5-156479488-G-A HAVCR1 c.557C>T p.Thr186Met Missense 3/8 -
7-99366077-T-C CYP3A4 c.570A>G p.Gly190Gly Synonymous 7/13 -
20-61292444-G-A SLCO4A1 c.1038G>A p.Ala346Ala Synonymous 5/12 -
10-96702007-G-A CYP2C9 c.390G>A p.Thr130Thr Synonymous 3/9 -
6-43411549-C-T ABCC10 c.2333-122C>T - IntronicSNV - 8/19
15-90344575-G-A ANPEP c.1742+91C>T - IntronicSNV - 11/20
3-42917047-A-C CYP8B1 c.262T>G p.Ser88Ala Missense 1/1 -
3-42917047-A-G CYP8B1 c.262T>C p.Ser88Pro Missense 1/1 -
6-160557154-G-C SLC22A1 c.840-98G>C - IntronicSNV - 4/10
6-160557154-G-A SLC22A1 c.840-98G>A - IntronicSNV - 4/10
1-11805782-T-C AGTRAP c.28-78T>C - IntronicSNV - 1/4
19-41515837-G-A CYP2B6 c.823-62G>A - IntronicSNV - 5/8
9-130914182-C-T LCN2 c.356-3C>T - IntronicSNV - 3/6
12-21428307-G-A SLCO1A2 c.1662C>T p.Cys554Cys Synonymous 12/14 -
20-61297955-C-A SLCO4A1 c.1472+28C>A - IntronicSNV - 7/11
17-61574662-C-A ACE c.3856C>A p.Arg1286Ser Missense 25/25 -
12-21358933-G-C SLCO1B1 c.1463G>C p.Gly488Ala Missense 11/15 -
6-160553372-G-T SLC22A1 c.624G>T p.Leu208Leu Synonymous 3/11 -
6-160553372-G-A SLC22A1 c.624G>A p.Leu208Leu Synonymous 3/11 -
11-62782446-C-A SLC22A8 c.1-16G>T - 5-UTRSNV 2/11 -
15-90335534-G-T ANPEP c.2385C>A p.Thr795Thr Synonymous 18/21 -
19-41355738-C-A CYP2A6 c.328G>T p.Val110Phe Missense 2/9 -
19-41355775-C-T CYP2A6 c.291G>A p.Glu97Glu Synonymous 2/9 -
4-89039434-A-T ABCG2 c.690-22T>A - IntronicSNV - 6/15
8-27456130-G-C CLU c.1187C>G p.Ser396Trp Missense 8/9 -
8-27456130-G-A CLU c.1187C>T p.Ser396Leu Missense 8/9 -
15-90333851-G-A ANPEP c.2670-79C>T - IntronicSNV - 19/20
15-90335534-G-A ANPEP c.2385C>T p.Thr795Thr Synonymous 18/21 -
15-90335534-G-C ANPEP c.2385C>G p.Thr795Thr Synonymous 18/21 -
10-135352268-C-G CYP2E1 c.1298-16C>G - IntronicSNV - 8/8
19-41518221-T-C CYP2B6 c.983T>C p.Ile328Thr Missense 7/9 -
16-28617595-A-G SULT1A1 c.595-38T>C - IntronicSNV - 6/7
6-31237723-G-A HLA-C c.1015+20C>T - IntronicSNV - 5/7
7-87168575-T-C ABCB1 c.2397+9A>G - IntronicSNV - 20/28
7-87168575-T-G ABCB1 c.2397+9A>C - IntronicSNV - 20/28
12-21349657-A-C SLCO1B1 c.728-223A>C - IntronicSNV - 7/14
12-21013948-C-T SLCO1B3 c.360-3C>T - IntronicSNV - 5/15
16-28617413-A-G SULT1A1 c.739T>C p.Phe247Leu Missense 7/8 -
3-119528879-C-T NR1I2 c.198-29C>T - IntronicSNV - 2/8
11-74883599-C-T SLCO2B1 c.957C>T p.Asp319Asp Synonymous 7/14 -
7-87160618-A-T ABCB1 c.2677T>A p.Ser893Thr Missense 22/29 -
6-31239543-C-G HLA-C c.176G>C p.Arg59Pro Missense 2/8 -
10-101590186-C-T ABCC2 c.2743C>T p.Arg915Cys Missense 20/32 -
10-101554150-G-A ABCC2 c.577-20G>A - IntronicSNV - 5/31
6-31323991-C-T HLA-B c.572G>A p.Trp191* Nonsense 3/8 -
11-64332891-C-G SLC22A11 c.1058+82C>G - IntronicSNV - 6/9
1-171077372-C-G FMO3 c.627+10C>G - IntronicSNV - 5/8
1-171077372-C-A FMO3 c.627+10C>A - IntronicSNV - 5/8
15-90335379-G-C ANPEP c.2528+12C>G - IntronicSNV - 18/20
15-90335379-G-A ANPEP c.2528+12C>T - IntronicSNV - 18/20
3-121631883-C-T SLC15A2 c.444C>T p.Ile148Ile Synonymous 5/22 -
10-101568013-C-G ABCC2 c.1815+27C>G - IntronicSNV - 13/31
22-25011179-G-T GGT1 c.382+85G>T - IntronicSNV - 7/15
12-21329738-A-T SLCO1B1 c.388A>T p.Asn130Tyr Missense 5/15 -
12-21457352-C-T SLCO1A2 c.589+9G>A - IntronicSNV - 5/13
11-74883577-G-A SLCO2B1 c.935G>A p.Arg312Gln Missense 7/14 -
5-101627411-C-T SLCO4C1 c.356-101G>A - IntronicSNV - 1/12
6-31239543-C-T HLA-C c.176G>A p.Arg59Gln Missense 2/8 -
20-61299073-C-G SLCO4A1 c.1473-24C>G - IntronicSNV - 7/11
20-61299073-C-A SLCO4A1 c.1473-24C>A - IntronicSNV - 7/11
1-171173237-G-A FMO2 c.827+34G>A - IntronicSNV - 6/8
17-61562553-G-A ACE c.1922-44G>A - IntronicSNV - 12/24
21-43732312-G-A TFF3 c.*54C>T - 3-UTRSNV 3/3 -
11-62744751-G-A SLC22A6 c.1470C>T p.Tyr490Tyr Synonymous 9/10 -
6-31323991-C-A HLA-B c.572G>T p.Trp191Leu Missense 3/8 -
6-31323991-C-G HLA-B c.572G>C p.Trp191Ser Missense 3/8 -
1-171077372-C-T FMO3 c.627+10C>T - IntronicSNV - 5/8
3-121631883-C-G SLC15A2 c.444C>G p.Ile148Met Missense 5/22 -
6-31237027-C-T HLA-C c.1097-77G>A - IntronicSNV - 7/7
1-171254588-C-T FMO1 c.1504C>T p.Arg502* Nonsense 9/9 -
6-31324064-T-C HLA-B c.499A>G p.Thr167Ala Missense 3/8 -
22-25010746-T-C GGT1 c.168T>C p.Asp56Asp Synonymous 6/16 -
22-25011179-G-A GGT1 c.382+85G>A - IntronicSNV - 7/15
6-31322303-C-G HLA-B c.1046G>C p.Cys349Ser Missense 7/8 -
11-74883577-G-T SLCO2B1 c.935G>T p.Arg312Leu Missense 7/14 -
4-155525486-G-T FGG c.*500C>A - IntergenicSNV 9/9 -
3-133667507-T-C SLCO2A1 c.978A>G p.Ser326Ser Synonymous 8/14 -
6-43413094-G-A ABCC10 c.2946+42G>A - IntronicSNV - 12/19
15-75042692-T-G CYP1A2 c.613T>G p.Phe205Val Missense 2/7 -
15-92669184-G-A SLCO3A1 c.1175-107G>A - IntronicSNV - 5/9
19-41356225-C-A CYP2A6 c.107G>T p.Gly36Val Missense 1/9 -
7-99315314-A-T CYP3A7 c.319-52T>A - IntronicSNV - 4/12
3-119534322-C-A NR1I2 c.1054+36C>A - IntronicSNV - 7/8
3-119534322-C-G NR1I2 c.1054+36C>G - IntronicSNV - 7/8
3-119534322-C-T NR1I2 c.1054+36C>T - IntronicSNV - 7/8
15-92647834-A-G SLCO3A1 c.1009+62A>G - IntronicSNV - 4/9
11-112025916-G-A IL18 c.1-140C>T - IntronicSNV - 1/5
13-95735326-C-T ABCC4 c.2686+68G>A - IntronicSNV - 21/30
19-41351771-C-T CYP2A6 c.973+90G>A - IntronicSNV - 6/8
17-61574492-G-A ACE c.3692-6G>A - IntronicSNV - 24/24
7-87165750-C-T ABCB1 c.2481+24G>A - IntronicSNV - 21/28
10-96748635-C-A CYP2C9 c.1323C>A p.Ala441Ala Synonymous 9/9 -
7-87165750-C-G ABCB1 c.2481+24G>C - IntronicSNV - 21/28
6-31324003-T-A HLA-B c.560A>T p.Glu187Val Missense 3/8 -
1-67515309-C-T SLC35D1 c.533+156G>A - IntronicSNV - 6/11
6-31324206-G-A HLA-B c.357C>T p.Leu119Leu Synonymous 3/8 -
10-96798578-G-T CYP2C8 c.1291+76C>A - IntronicSNV - 8/8
7-99366068-G-A CYP3A4 c.579C>T p.Ile193Ile Synonymous 7/13 -
13-95839003-G-A ABCC4 c.1497C>T p.Tyr499Tyr Synonymous 11/31 -
20-61297895-C-T SLCO4A1 c.1440C>T p.Pro480Pro Synonymous 7/12 -
1-98015146-T-C DPYD c.1494A>G p.Gln498Gln Synonymous 12/23 -
1-98015146-T-A DPYD c.1494A>T p.Gln498His Missense 12/23 -
1-171174691-G-A FMO2 c.1101G>A p.Ala367Ala Synonymous 7/9 -
6-160553165-C-T SLC22A1 c.516-99C>T - IntronicSNV - 2/10
1-97981587-C-T DPYD c.1525-90G>A - IntronicSNV - 12/22
1-97981587-C-A DPYD c.1525-90G>T - IntronicSNV - 12/22
10-96535246-G-C CYP2C19 c.431G>C p.Arg144Pro Missense 3/9 -
10-96535246-G-A CYP2C19 c.431G>A p.Arg144His Missense 3/9 -
6-160553176-G-A SLC22A1 c.516-88G>A - IntronicSNV - 2/10
6-160553176-G-T SLC22A1 c.516-88G>T - IntronicSNV - 2/10
6-43411599-T-G ABCC10 c.2333-72T>G - IntronicSNV - 8/19
1-67515309-C-G SLC35D1 c.533+156G>C - IntronicSNV - 6/11
10-96701850-T-C CYP2C9 c.331+73T>C - IntronicSNV - 2/8
12-21054369-G-A SLCO1B3 c.1833G>A p.Gly611Gly Synonymous 15/16 -
1-97771947-C-A DPYD c.2059-94G>T - IntronicSNV - 16/22
6-31238029-T-C HLA-C c.853A>G p.Met285Val Missense 4/8 -
6-160551204-G-A SLC22A1 c.480G>A p.Leu160Leu Synonymous 2/11 -
6-160551204-G-C SLC22A1 c.480G>C p.Leu160Phe Missense 2/11 -
6-160551204-G-T SLC22A1 c.480G>T p.Leu160Phe Missense 2/11 -
7-87165750-C-A ABCB1 c.2481+24G>T - IntronicSNV - 21/28
3-121647930-G-A SLC15A2 c.1443G>A p.Val481Val Synonymous 16/22 -
1-98060579-T-C DPYD c.958+36A>G - IntronicSNV - 9/22
3-121641821-A-G SLC15A2 c.868-66A>G - IntronicSNV - 9/21
17-61557689-C-A ACE c.656-9C>A - IntronicSNV - 4/24
3-121647930-G-C SLC15A2 c.1443G>C p.Val481Val Synonymous 16/22 -
3-121647930-G-T SLC15A2 c.1443G>T p.Val481Val Synonymous 16/22 -
19-41354170-C-G CYP2A6 c.608G>C p.Arg203Pro Missense 4/9 -
4-155505231-T-G FGA c.*45A>C - 3-UTRSNV 6/6 -
19-41352762-G-C CYP2A6 c.831+18C>G - IntronicSNV - 5/8
19-41354170-C-T CYP2A6 c.608G>A p.Arg203His Missense 4/9 -
20-61296183-G-A SLCO4A1 c.1122-103G>A - IntronicSNV - 5/11
7-99317993-G-A CYP3A7 c.261C>T p.Pro87Pro Synonymous 4/13 -
3-119526058-T-C NR1I2 c.1-40T>C - IntronicSNV - 1/8
1-171168584-C-G FMO2 c.584C>G p.Ser195* Nonsense 5/9 -
1-171168584-C-T FMO2 c.584C>T p.Ser195Leu Missense 5/9 -
1-171168584-C-A FMO2 c.584C>A p.Ser195* Nonsense 5/9 -
12-20968828-C-T SLCO1B3 c.84+72C>T - IntronicSNV - 3/15
22-25016559-G-A GGT1 c.575+72G>A - IntronicSNV - 8/15
5-156479572-A-G HAVCR1 c.473T>C p.Met158Thr Missense 3/8 -
12-21294329-T-C SLCO1B1 c.1-180T>C - IntronicSNV - 1/14
3-119526176-C-T NR1I2 c.79C>T p.Pro27Ser Missense 2/9 -
6-160560845-A-G SLC22A1 c.1222A>G p.Met408Val Missense 7/11 -
15-75044400-G-C CYP1A2 c.1043-65G>C - IntronicSNV - 4/6
6-31324023-C-T HLA-B c.540G>A p.Arg180Arg Synonymous 3/8 -
3-121642048-A-T SLC15A2 c.958-21A>T - IntronicSNV - 10/21
16-28617361-G-C SULT1A1 c.775+16C>G - IntronicSNV - 7/7
6-31323065-G-C HLA-B c.895+29C>G - IntronicSNV - 4/7
3-133748336-G-A SLCO2A1 c.96+215C>T - IntronicSNV - 1/13
22-42523805-C-T CYP2D6 c.985+39G>A - IntronicSNV - 6/8
12-21294795-A-T SLCO1B1 c.84+203A>T - IntronicSNV - 2/14
6-31324210-G-T HLA-B c.353C>A p.Thr118Asn Missense 3/8 -
6-31324210-G-A HLA-B c.353C>T p.Thr118Ile Missense 3/8 -
13-95696757-T-C ABCC4 c.3457-65A>G - IntronicSNV - 27/30
4-155507658-C-T FGA c.923G>A p.Arg308Gln Missense 5/6 -
12-21294795-A-G SLCO1B1 c.84+203A>G - IntronicSNV - 2/14
15-90347443-C-A ANPEP c.1179+41G>T - IntronicSNV - 6/20
5-156482099-T-C HAVCR1 c.379+113A>G - IntronicSNV - 2/7
6-43415002-G-C ABCC10 c.3477G>C p.Ser1159Ser Synonymous 15/20 -
6-43415002-G-T ABCC10 c.3477G>T p.Ser1159Ser Synonymous 15/20 -
1-110231592-T-C GSTM1 c.178-78T>C - IntronicSNV - 3/7
2-234676702-T-G UGT1A1 c.1084+120T>G - IntronicSNV - 3/4
6-160575751-A-G SLC22A1 c.1386-79A>G - IntronicSNV - 8/10
12-21428371-T-C SLCO1A2 c.1611-13A>G - IntronicSNV - 11/13
10-101611294-G-A ABCC2 c.4544G>A p.Cys1515Tyr Missense 32/32 -
6-31323012-G-A HLA-B c.896-12C>T - IntronicSNV - 4/7
1-171168709-G-A FMO2 c.627+82G>A - IntronicSNV - 5/8
10-96827120-A-T CYP2C8 c.332-6T>A - IntronicSNV - 2/8
12-21353557-C-T SLCO1B1 c.1086C>T p.Tyr362Tyr Synonymous 9/15 -
6-31237664-C-T HLA-C c.1015+79G>A - IntronicSNV - 5/7
7-17373654-C-T AHR c.824C>T p.Pro275Leu Missense 7/11 -
6-31324892-G-A HLA-B c.44C>T p.Ala15Val Missense 1/8 -
6-31237437-T-C HLA-C c.1016-135A>G - IntronicSNV - 5/7
13-95847145-G-A ABCC4 c.1208C>T p.Pro403Leu Missense 9/31 -
6-31237461-G-A HLA-C c.1016-159C>T - IntronicSNV - 5/7
17-61559019-G-A ACE c.1038G>A p.Ser346Ser Synonymous 7/25 -
17-61559019-G-C ACE c.1038G>C p.Ser346Ser Synonymous 7/25 -
6-31324064-T-A HLA-B c.499A>T p.Thr167Ser Missense 3/8 -
10-101591334-G-T ABCC2 c.2884-34G>T - IntronicSNV - 21/31
13-95735378-G-A ABCC4 c.2686+16C>T - IntronicSNV - 21/30
10-101591334-G-C ABCC2 c.2884-34G>C - IntronicSNV - 21/31
13-95735378-G-C ABCC4 c.2686+16C>G - IntronicSNV - 21/30
6-31239407-G-A HLA-C c.312C>T p.Asn104Asn Synonymous 2/8 -
6-31323233-A-T HLA-B c.756T>A p.Thr252Thr Synonymous 4/8 -
22-42523943-A-T CYP2D6 c.886T>A p.Cys296Ser Missense 6/9 -
6-31322229-A-G HLA-B c.*31T>C - IntronicSNV 8/8 -
7-99277534-T-G CYP3A5 c.1-15A>C - 5-UTRSNV 1/13 -
11-64323879-A-T SLC22A11 c.393+15A>T - IntronicSNV - 1/9
3-133663862-A-G SLCO2A1 c.1461+77T>C - IntronicSNV - 10/13
1-97544543-G-T DPYD c.3067C>A p.Pro1023Thr Missense 23/23 -
10-135342260-C-T CYP2E1 c.337+116C>T - IntronicSNV - 2/8
6-31323233-A-C HLA-B c.756T>G p.Thr252Thr Synonymous 4/8 -
10-96798695-C-G CYP2C8 c.1250G>C p.Gly417Ala Missense 8/9 -
7-99262835-C-T CYP3A5 c.624G>A p.Lys208Lys Synonymous 7/13 -
13-95705307-C-T ABCC4 c.3456+42G>A - IntronicSNV - 27/30
4-155531333-A-G FGG c.418T>C p.Tyr140His Missense 5/9 -
13-95725343-A-T ABCC4 c.3018+115T>A - IntronicSNV - 24/30
12-21349611-C-T SLCO1B1 c.728-269C>T - IntronicSNV - 7/14
10-101553640-T-C ABCC2 c.469-9T>C - IntronicSNV - 4/31
10-135352520-T-C CYP2E1 c.*52T>C - 3-UTRSNV 9/9 -
16-28618238-A-G SULT1A1 c.499+34T>C - IntronicSNV - 5/7
10-96535098-T-A CYP2C19 c.332-49T>A - IntronicSNV - 2/8
4-89052964-G-A ABCG2 c.369C>T p.Tyr123Tyr Synonymous 4/16 -
1-98386496-C-G DPYD c.1-18G>C - 5-UTRSNV 1/23 -
11-74862391-A-G SLCO2B1 c.1-36A>G - 5-UTRSNV 1/14 -
11-62763544-A-T SLC22A8 c.842T>A p.Val281Asp Missense 6/11 -
3-121659860-C-T SLC15A2 c.*6C>T - 3-UTRSNV 22/22 -
11-62751812-T-C SLC22A6 c.351A>G p.Pro117Pro Synonymous 1/10 -
3-119534153-C-T NR1I2 c.938-17C>T - IntronicSNV - 6/8
6-31239790-G-A HLA-C c.59C>T p.Thr20Ile Missense 1/8 -
12-21350034-G-A SLCO1B1 c.882G>A p.Leu294Leu Synonymous 8/15 -
4-155525486-G-C FGG c.*500C>G - IntergenicSNV 9/9 -
6-31239417-C-G HLA-C c.302G>C p.Ser101Thr Missense 2/8 -
6-31237893-G-T HLA-C c.896-31C>A - IntronicSNV - 4/7
3-121659197-G-A SLC15A2 c.1909-34G>A - IntronicSNV - 20/21
11-62763544-A-G SLC22A8 c.842T>C p.Val281Ala Missense 6/11 -
3-119534153-C-G NR1I2 c.938-17C>G - IntronicSNV - 6/8
3-133667646-C-T SLCO2A1 c.940+91G>A - IntronicSNV - 7/13
1-98039541-A-G DPYD c.1129-15T>C - IntronicSNV - 10/22
20-61292536-C-G SLCO4A1 c.1121+9C>G - IntronicSNV - 5/11
6-31322174-C-G HLA-B c.*86G>C - IntronicSNV - 7/7
6-43417852-G-C ABCC10 c.*23G>C - 3-UTRSNV 20/20 -
1-171072862-G-T FMO3 c.133-64G>T - IntronicSNV - 2/8
6-31239790-G-C HLA-C c.59C>G p.Thr20Ser Missense 1/8 -
6-31324756-G-A HLA-B c.74-22C>T - IntronicSNV - 1/7
22-42523943-A-G CYP2D6 c.886T>C p.Cys296Arg Missense 6/9 -
22-25011027-C-T GGT1 c.315C>T p.Asn105Asn Synonymous 7/16 -
10-101601664-T-C ABCC2 c.3615-60T>C - IntronicSNV - 25/31
1-171173089-G-A FMO2 c.713G>A p.Arg238Gln Missense 6/9 -
15-90333645-T-G ANPEP c.2751+46A>C - IntronicSNV - 20/20
1-171162547-T-A FMO2 c.206T>A p.Phe69Tyr Missense 3/9 -
5-101606616-T-C SLCO4C1 c.620-106A>G - IntronicSNV - 2/12
4-155506763-C-T FGA c.1818G>A p.Glu606Glu Synonymous 5/6 -
13-95696540-C-T ABCC4 c.3609G>A p.Ala1203Ala Synonymous 28/31 -
13-95768387-A-G ABCC4 c.2456-132T>C - IntronicSNV - 19/30
3-133748333-C-CACAT SLCO2A1 c.96+217_96+218insATGT - IntronicInsertion - 1/13
8-27457507-G-C CLU c.954C>G p.Pro318Pro Synonymous 7/9 -
12-21453466-G-A SLCO1A2 c.726C>T p.Val242Val Synonymous 7/14 -
6-31324003-T-G HLA-B c.560A>C p.Glu187Ala Missense 3/8 -
1-97544618-T-C DPYD c.2992A>G p.Ile998Val Missense 23/23 -
1-97544618-T-A DPYD c.2992A>T p.Ile998Phe Missense 23/23 -
1-11808664-A-C AGTRAP c.361A>C p.Thr121Pro Missense 4/5 -
1-11808664-A-G AGTRAP c.361A>G p.Thr121Ala Missense 4/5 -
4-155507677-G-C FGA c.904C>G p.Pro302Ala Missense 5/6 -
6-31238048-C-T HLA-C c.834G>A p.Glu278Glu Synonymous 4/8 -
4-155507677-G-T FGA c.904C>A p.Pro302Thr Missense 5/6 -
17-61560938-C-T ACE c.1586+19C>T - IntronicSNV - 10/24
5-156464212-T-G HAVCR1 c.952+46A>C - IntronicSNV - 6/7
16-66977094-G-A CES2 c.1421-108G>A - intron_variant - 10/11
5-101574970-T-C SLCO4C1 c.1999A>G p.Met667Val Missense 12/13 -
22-25024016-C-T GGT1 c.1337-32C>T - IntronicSNV - 13/15
12-21015596-C-T SLCO1B3 c.629-94C>T - IntronicSNV - 7/15
8-18074388-G-A NAT1 c.-85-2532G>A - intron_variant - 1/2
16-66975582-G-C CES2 c.1056+33G>C - intron_variant - 7/11
10-101577132-TTT-T ABCC2 c.2162_2163delTT p.Phe721Trpfs*5 Frameshift 17/32 -
16-66969400-G-T CES2 c.54G>T p.Gln18His Missense 1/12 -
6-160575985-C-T SLC22A1 c.1498+43C>T - IntronicSNV - 9/10
3-42916879-G-A CYP8B1 c.430C>T p.Leu144Leu Synonymous 1/1 -
8-18074388-G-T NAT1 c.-85-2532G>T - intron_variant - 1/2
6-160557408-G-T SLC22A1 c.954+42G>T - IntronicSNV - 5/10
1-161203079-C-T NR1I3 c.288G>A p.Gln96Gln Synonymous 4/9 -
13-95859974-T-C ABCC4 c.911+80A>G - IntronicSNV - 7/30
11-64326676-G-A SLC22A11 c.463G>A p.Val155Met Missense 2/10 -
11-64338485-G-A SLC22A11 c.1624G>A p.Ala542Thr Missense 10/10 -
6-160553007-C-T SLC22A1 c.516-257C>T - IntronicSNV - 2/10
15-90346861-C-A ANPEP c.1437+17G>T - IntronicSNV - 8/20
1-171174531-A-G FMO2 c.941A>G p.Glu314Gly Missense 7/9 -
1-171085385-T-A FMO3 c.1221T>A p.Asn407Lys Missense 8/9 -
1-171085385-T-C FMO3 c.1221T>C p.Asn407Asn Synonymous 8/9 -
10-96522517-A-C CYP2C19 c.55A>C p.Ile19Leu Missense 1/9 -
15-90348478-G-A ANPEP c.758-30C>T - IntronicSNV - 3/20
2-234681158-GG-AC UGT1A7 c.1546_1547delGGinsAC p.Gly516Thr Missense 5/5 -
15-90346861-C-T ANPEP c.1437+17G>A - IntronicSNV - 8/20
13-95735582-A-G ABCC4 c.2536-38T>C - IntronicSNV - 20/30
6-31322911-C-T HLA-B c.985G>A p.Ala329Thr Missense 5/8 -
6-31322911-C-G HLA-B c.985G>C p.Ala329Pro Missense 5/8 -
6-43412518-C-G ABCC10 c.2606-8C>G - IntronicSNV - 10/19
10-101544447-A-T ABCC2 c.116A>T p.Tyr39Phe Missense 2/32 -
22-42463814-C-G NAGA c.279G>C p.Pro93Pro Synonymous 3/9 -
10-96741058-C-G CYP2C9 c.1080C>G p.Asp360Glu Missense 7/9 -
3-121648168-G-A SLC15A2 c.1526G>A p.Arg509Lys Missense 17/22 -
22-42463814-C-T NAGA c.279G>A p.Pro93Pro Synonymous 3/9 -
7-87225252-A-C ABCB1 c.69-122T>G - IntronicSNV - 3/28
7-87225252-A-G ABCB1 c.69-122T>C - IntronicSNV - 3/28
12-21428247-T-G SLCO1A2 c.1675+47A>C - IntronicSNV - 12/13
12-21428247-T-C SLCO1A2 c.1675+47A>G - IntronicSNV - 12/13
8-27457512-T-G CLU c.949A>C p.Asn317His Missense 7/9 -
13-95768362-T-C ABCC4 c.2456-107A>G - IntronicSNV - 19/30
10-96824406-C-T CYP2C8 c.642+151G>A - IntronicSNV - 4/8
11-74876951-G-A SLCO2B1 c.405G>A p.Pro135Pro Synonymous 4/14 -
7-87138659-A-T ABCB1 c.3421T>A p.Ser1141Thr Missense 27/29 -
8-18079521-A-T NAT1 c.1-36A>T - IntronicSNV - 2/2
7-99250394-A-G CYP3A5 c.1035T>C p.Pro345Pro Synonymous 11/13 -
12-20968683-A-G SLCO1B3 c.11A>G p.His4Arg Missense 3/16 -
5-156484800-C-T HAVCR1 c.46+109G>A - IntronicSNV - 1/7
22-25017006-G-A GGT1 c.702G>A p.Thr234Thr Synonymous 9/16 -
4-89053790-G-A ABCG2 c.204-3C>T - IntronicSNV - 2/15
6-160557704-C-T SLC22A1 c.1061+22C>T - IntronicSNV - 6/10
6-31237975-T-A HLA-C c.895+12A>T - IntronicSNV - 4/7
6-160564522-G-A SLC22A1 c.1277-51G>A - IntronicSNV - 7/10
1-11808239-G-C AGTRAP c.169-233G>C - IntronicSNV - 3/4
13-95768084-G-A ABCC4 c.2535+92C>T - IntronicSNV - 20/30
19-41354660-A-G CYP2A6 c.352T>C p.Phe118Leu Missense 3/9 -
5-156469783-G-A HAVCR1 c.782-90C>T - IntronicSNV - 4/7
10-96796861-G-A CYP2C8 c.*24C>T - 3-UTRSNV 9/9 -
5-156482357-C-T HAVCR1 c.234G>A p.Lys78Lys Synonymous 2/8 -
3-133698349-C-T SLCO2A1 c.210G>A p.Ser70Ser Synonymous 2/14 -
1-171173160-C-T FMO2 c.784C>T p.Arg262Trp Missense 6/9 -
15-90347920-G-A ANPEP c.898-72C>T - IntronicSNV - 4/20
10-101554030-C-T ABCC2 c.577-140C>T - IntronicSNV - 5/31
1-171076966-G-A FMO3 c.472G>A p.Glu158Lys Missense 4/9 -
11-62751911-C-T SLC22A6 c.252G>A p.Pro84Pro Synonymous 1/10 -
11-62751911-C-A SLC22A6 c.252G>T p.Pro84Pro Synonymous 1/10 -
5-156479569-GT-GTGT HAVCR1 c.475_476dup p.Thr160Argfs*12 Frameshift 3/8 -
11-62747083-G-A SLC22A6 c.1253-15C>T - IntronicSNV - 7/9
11-62747083-G-T SLC22A6 c.1253-15C>A - IntronicSNV - 7/9
6-31239407-G-T HLA-C c.312C>A p.Asn104Lys Missense 2/8 -
6-31237876-A-G HLA-C c.896-14T>C - IntronicSNV - 4/7
8-27462385-G-T CLU c.829+56C>A - IntronicSNV - 5/8
8-27462385-G-C CLU c.829+56C>G - IntronicSNV - 5/8
7-99366068-G-C CYP3A4 c.579C>G p.Ile193Met Missense 7/13 -
6-31324051-C-A HLA-B c.512G>T p.Trp171Leu Missense 3/8 -
19-41355919-A-C CYP2A6 c.181-34T>G - IntronicSNV - 1/8
20-61290242-C-T SLCO4A1 c.887+123C>T - IntronicSNV - 3/11
6-31324051-C-T HLA-B c.512G>A p.Trp171* Nonsense 3/8 -
12-21355537-G-A SLCO1B1 c.1248G>A p.Val416Val Synonymous 10/15 -
6-31322885-T-A HLA-B c.1011A>T p.Ser337Ser Synonymous 5/8 -
1-171082954-G-A FMO3 c.828-193G>A - IntronicSNV - 6/8
16-28617354-C-A SULT1A1 c.775+23G>T - IntronicSNV - 7/7
12-21068699-C-T SLCO1B3 c.1866-239C>T - IntronicSNV - 15/15
6-31239501-G-C HLA-C c.218C>G p.Ala73Gly Missense 2/8 -
6-31239501-G-T HLA-C c.218C>A p.Ala73Glu Missense 2/8 -
10-96818106-T-A CYP2C8 c.805A>T p.Ile269Phe Missense 5/9 -
11-62749344-G-C SLC22A6 c.767C>G p.Ala256Gly Missense 4/10 -
7-87133538-A-G ABCB1 c.*21T>C - 3-UTRSNV 29/29 -
6-160557158-G-A SLC22A1 c.840-94G>A - IntronicSNV - 4/10
15-90344716-C-T ANPEP c.1692G>A p.Glu564Glu Synonymous 11/21 -
19-41522804-G-A CYP2B6 c.*72G>A - 3-UTRSNV 9/9 -
8-27464081-C-T CLU c.247-40G>A - IntronicSNV - 3/8
1-67518534-C-A SLC35D1 c.244G>T p.Ala82Ser Missense 3/12 -
1-110232752-A-G GSTM1 c.361-141A>G - IntronicSNV - 5/7
11-74915586-G-A SLCO2B1 c.2091G>A p.Val697Val Synonymous 14/14 -
11-62761161-C-T SLC22A8 c.1326-62G>A - IntronicSNV - 9/10
6-31324151-C-G HLA-B c.412G>C p.Asp138His Missense 3/8 -
6-43417880-G-C ABCC10 c.*51G>C - 3-UTRSNV 20/20 -
6-31237230-A-G HLA-C c.1048+40T>C - IntronicSNV - 6/7
3-133673940-C-A SLCO2A1 c.495G>T p.Glu165Asp Missense 4/14 -
15-45008414-G-A B2M c.347-113G>A - IntronicSNV - 2/3
15-45003839-G-C B2M c.67+28G>C - IntronicSNV - 1/3
13-95748456-T-A ABCC4 c.2536-12912A>T - IntronicSNV - 20/30
13-95748456-T-C ABCC4 c.2536-12912A>G - IntronicSNV - 20/30
12-21428169-G-A SLCO1A2 c.1675+125C>T - IntronicSNV - 12/13
1-161202556-T-C NR1I3 c.548+41A>G - IntronicSNV - 5/8
15-90344963-A-C ANPEP c.1570-125T>G - IntronicSNV - 10/20
17-61573761-T-G ACE c.3387T>G p.Phe1129Leu Missense 23/25 -
19-41515952-G-A CYP2B6 c.876G>A p.Thr292Thr Synonymous 6/9 -
4-89020438-C-T ABCG2 c.1492+38G>A - IntronicSNV - 12/15
8-18258316-G-A NAT2 c.803G>A p.Arg268Lys Missense 2/2 -
8-18258316-G-T NAT2 c.803G>T p.Arg268Ile Missense 2/2 -
4-89016782-A-G ABCG2 c.1648-21T>C - IntronicSNV - 13/15
6-31324829-G-C HLA-B c.73+34C>G - IntronicSNV - 1/7
19-41497295-C-A CYP2B6 c.85C>A p.Arg29Ser Missense 1/9 -
7-87179443-G-A ABCB1 c.1350+44C>T - IntronicSNV - 13/28
7-87179616-C-T ABCB1 c.1225-4G>A - IntronicSNV - 12/28
15-90347814-G-A ANPEP c.932C>T p.Ala311Val Missense 5/21 -
10-101567786-A-T ABCC2 c.1669-54A>T - IntronicSNV - 12/31
3-119530595-C-T NR1I2 c.519+22C>T - IntronicSNV - 4/8
10-96740958-T-C CYP2C9 c.980T>C p.Ile327Thr Missense 7/9 -
12-21331625-C-T SLCO1B1 c.597C>T p.Phe199Phe Synonymous 6/15 -
15-90346392-C-A ANPEP c.1569+78G>T - IntronicSNV - 10/20
15-90346392-C-T ANPEP c.1569+78G>A - IntronicSNV - 10/20
19-41350475-A-C CYP2A6 c.1303+61T>G - IntronicSNV - 8/8
19-41354661-T-C CYP2A6 c.351A>G p.Val117Val Synonymous 3/9 -
10-96798658-T-C CYP2C8 c.1287A>G p.Ser429Ser Synonymous 8/9 -
4-155526028-C-T FGG c.1320G>A p.Ala440Ala Synonymous 9/9 -
19-41497295-C-T CYP2B6 c.85C>T p.Arg29Cys Missense 1/9 -
9-130915466-G-A LCN2 c.*68G>A - IntronicSNV - 6/6
11-112025916-G-C IL18 c.1-140C>G - IntronicSNV - 1/5
3-121647286-C-T SLC15A2 c.1225C>T p.Pro409Ser Missense 15/22 -
11-74911307-C-A SLCO2B1 c.1638C>A p.Asn546Lys Missense 11/14 -
11-64331677-A-G SLC22A11 c.822-103A>G - IntronicSNV - 4/9
11-64323508-G-A SLC22A11 c.37G>A p.Val13Met Missense 1/10 -
16-66977895-C-T CES2 c.1647C>T - synonymous_variant 12/12 -
17-61560763-T-C ACE c.1488-58T>C - IntronicSNV - 9/24
10-135341013-G-A CYP2E1 c.114G>A p.Pro38Pro Synonymous 1/9 -
2-234676630-G-A UGT1A1 c.1084+48G>A - IntronicSNV - 3/4
16-28617574-C-T SULT1A1 c.595-17G>A - IntronicSNV - 6/7
15-90334309-G-T ANPEP c.2544C>A p.Thr848Thr Synonymous 19/21 -
4-155511773-A-G FGA c.54+13T>C - IntronicSNV - 1/5
5-156479463-C-T HAVCR1 c.582G>A p.Thr194Thr Synonymous 3/8 -
15-45008434-T-C B2M c.347-93T>C - IntronicSNV - 2/3
11-74875013-C-T SLCO2B1 c.153C>T p.Phe51Phe Synonymous 3/14 -
16-66969400-G-A CES2 c.54G>A p.Gln18Gln Synonymous 1/12 -
11-74911397-T-C SLCO2B1 c.1728T>C p.Cys576Cys Synonymous 11/14 -
19-41512792-C-T CYP2B6 c.485-18C>T - IntronicSNV - 3/8
6-31324742-T-C HLA-B c.74-8A>G - IntronicSNV - 1/7
4-155507590-T-C FGA c.991A>G p.Thr331Ala Missense 5/6 -
4-155507590-T-A FGA c.991A>T p.Thr331Ser Missense 5/6 -
6-31237405-C-T HLA-C c.1016-103G>A - IntronicSNV - 5/7
4-89060909-T-C ABCG2 c.203+36A>G - IntronicSNV - 2/15
16-28618071-C-G SULT1A1 c.594+11G>C - IntronicSNV - 6/7
12-21329738-A-G SLCO1B1 c.388A>G p.Asn130Asp Missense 5/15 -
4-155525545-A-G FGG c.*441T>C - IntergenicSNV 9/9 -
6-31324953-CTC-TTT HLA-B c.1-20_1-18delinsAAA - 5-UTRBlockSubstitution 1/8 -
17-61562322-T-C ACE c.1922-275T>C - IntronicSNV - 12/24
6-31239593-T-C HLA-C c.126A>G p.Gly42Gly Synonymous 2/8 -
6-31239593-T-A HLA-C c.126A>T p.Gly42Gly Synonymous 2/8 -
6-31239593-T-G HLA-C c.126A>C p.Gly42Gly Synonymous 2/8 -
8-27457479-C-T CLU c.982G>A p.Asp328Asn Missense 7/9 -
10-96580139-C-G CYP2C19 c.820-114C>G - IntronicSNV - 5/8
6-31324024-C-T HLA-B c.539G>A p.Arg180Gln Missense 3/8 -
1-161206370-G-C NR1I3 c.1-15C>G - 5-UTRSNV 2/9 -
22-42461918-G-A NAGA c.598-15C>T - IntronicSNV - 5/8
13-95725359-T-A ABCC4 c.3018+99A>T - IntronicSNV - 24/30
13-95725359-T-C ABCC4 c.3018+99A>G - IntronicSNV - 24/30
7-99310965-C-T CYP3A7 c.865+127G>A - IntronicSNV - 9/12
11-74907582-C-T SLCO2B1 c.1457C>T p.Ser486Phe Missense 10/14 -
19-41512841-G-A CYP2B6 c.516G>A p.Gln172Gln Synonymous 4/9 -
10-101610533-C-T ABCC2 c.4488C>T p.His1496His Synonymous 31/32 -
5-156479589-C-T HAVCR1 c.456G>A p.Thr152Thr Synonymous 3/8 -
7-87178727-C-T ABCB1 c.1662G>A p.Leu554Leu Synonymous 15/29 -
8-27461773-A-T CLU c.934+35T>A - IntronicSNV - 6/8
3-133653602-C-T SLCO2A1 c.1887G>A p.Lys629Lys Synonymous 14/14 -
5-156479589-C-G HAVCR1 c.456G>C p.Thr152Thr Synonymous 3/8 -
16-66977115-G-A CES2 c.1421-87G>A - intron_variant - 10/11
7-87178727-C-G ABCB1 c.1662G>C p.Leu554Leu Synonymous 15/29 -
3-119536069-C-T NR1I2 c.*10C>T - 3-UTRSNV 9/9 -
13-95715132-G-A ABCC4 c.3211-19C>T - IntronicSNV - 25/30
5-156479424-AGT-CGC HAVCR1 c.619_621delinsGCG p.Thr207Ala Missense 3/8 -
6-31322987-C-A HLA-B c.909G>T p.Gln303His Missense 5/8 -
6-31324921-C-T HLA-B c.15G>A p.Ala5Ala Synonymous 1/8 -
6-31324921-C-A HLA-B c.15G>T p.Ala5Ala Synonymous 1/8 -
13-95900071-C-T ABCC4 c.75-64G>A - IntronicSNV - 1/30
1-67487391-C-T SLC35D1 c.730-106G>A - IntronicSNV - 8/11
5-156464242-T-C HAVCR1 c.952+16A>G - IntronicSNV - 6/7
6-31237124-T-C HLA-C c.1087A>G p.Thr363Ala Missense 7/8 -
6-31237124-T-A HLA-C c.1087A>T p.Thr363Ser Missense 7/8 -
1-97544543-G-C DPYD c.3067C>G p.Pro1023Ala Missense 23/23 -
1-97544543-G-A DPYD c.3067C>T p.Pro1023Ser Missense 23/23 -
1-98058923-G-A DPYD c.979C>T p.Pro327Ser Missense 10/23 -
7-17378827-A-G AHR c.1378A>G p.Met460Val Missense 10/11 -
6-43399837-A-G ABCC10 c.1-11A>G - 5-UTRSNV 1/20 -
6-31323958-T-C HLA-B c.605A>G p.Lys202Arg Missense 3/8 -
6-31323958-T-G HLA-B c.605A>C p.Lys202Thr Missense 3/8 -
20-61287727-G-A SLCO4A1 c.1-80G>A - 5-UTRSNV 2/12 -
5-101597582-T-C SLCO4C1 c.1021+34A>G - IntronicSNV - 5/12
6-31239577-A-C HLA-C c.142T>G p.Ser48Ala Missense 2/8 -
3-119533733-G-T NR1I2 c.795-93G>T - IntronicSNV - 5/8
3-119533733-G-A NR1I2 c.795-93G>A - IntronicSNV - 5/8
22-42456473-C-G NAGA c.1102-56G>C - IntronicSNV - 8/8
6-31237333-T-A HLA-C c.1016-31A>T - IntronicSNV - 5/7
3-121649836-A-C SLC15A2 c.1664+39A>C - IntronicSNV - 18/21
3-121649836-A-G SLC15A2 c.1664+39A>G - IntronicSNV - 18/21
12-21008143-A-G SLCO1B3 c.226+40A>G - IntronicSNV - 4/15
15-75014569-T-C CYP1A1 c.825+45A>G - IntronicSNV - 2/6
19-41350475-A-T CYP2A6 c.1303+61T>A - IntronicSNV - 8/8
10-101606861-G-T ABCC2 c.4290G>T p.Val1430Val Synonymous 30/32 -
16-28620030-G-A SULT1A1 c.147C>T p.Ser49Ser Synonymous 2/8 -
6-43413094-G-T ABCC10 c.2946+42G>T - IntronicSNV - 12/19
7-17367299-A-C AHR c.361-84A>C - IntronicSNV - 3/10
11-74907489-C-T SLCO2B1 c.1434-70C>T - IntronicSNV - 9/13
22-25019155-T-C GGT1 c.815T>C p.Val272Ala Missense 10/16 -
11-74907489-C-G SLCO2B1 c.1434-70C>G - IntronicSNV - 9/13
6-31324154-G-C HLA-B c.409C>G p.His137Asp Missense 3/8 -
6-31324154-G-T HLA-B c.409C>A p.His137Asn Missense 3/8 -
6-31324154-G-A HLA-B c.409C>T p.His137Tyr Missense 3/8 -
1-98144610-A-G DPYD c.850+41T>C - IntronicSNV - 8/22
12-21358783-G-T SLCO1B1 c.1332-19G>T - IntronicSNV - 10/14
11-62752289-C-T SLC22A6 c.1-127G>A - 5-UTRSNV 1/10 -
12-21358783-G-A SLCO1B1 c.1332-19G>A - IntronicSNV - 10/14
12-21358783-G-C SLCO1B1 c.1332-19G>C - IntronicSNV - 10/14
1-67487395-G-C SLC35D1 c.730-110C>G - IntronicSNV - 8/11
12-21457434-T-G SLCO1A2 c.516A>C p.Glu172Asp Missense 5/14 -
8-18074536-G-C NAT1 c.-85-2384G>C - intron_variant - 1/2
19-41350582-C-G CYP2A6 c.1257G>C p.Glu419Asp Missense 8/9 -
1-110231380-G-A GSTM1 c.177+21G>A - IntronicSNV - 3/7
6-160575907-G-C SLC22A1 c.1463G>C p.Arg488Thr Missense 9/11 -
4-89053658-A-C ABCG2 c.263+70T>G - IntronicSNV - 3/15
6-160575907-G-T SLC22A1 c.1463G>T p.Arg488Met Missense 9/11 -
3-121643893-T-C SLC15A2 c.1124+13T>C - IntronicSNV - 13/21
1-11808236-A-G AGTRAP c.169-236A>G - IntronicSNV - 3/4
19-41497293-A-G CYP2B6 c.83A>G p.Asp28Gly Missense 1/9 -
15-92647304-G-C SLCO3A1 c.746-205G>C - IntronicSNV - 3/9
11-64331731-G-A SLC22A11 c.822-49G>A - IntronicSNV - 4/9
15-90349870-C-A ANPEP c.1-56G>T - 5-UTRSNV 2/21 -
1-11808602-C-T AGTRAP c.299C>T p.Pro100Leu Missense 4/5 -
15-90349870-C-T ANPEP c.1-56G>A - 5-UTRSNV 2/21 -
4-155505291-G-A FGA c.2586C>T p.Pro862Pro Synonymous 6/6 -
12-21331599-T-C SLCO1B1 c.571T>C p.Leu191Leu Synonymous 6/15 -
6-160553306-C-T SLC22A1 c.558C>T p.Asn186Asn Synonymous 3/11 -
13-95673791-A-C ABCC4 c.*38T>G - 3-UTRSNV 31/31 -
11-62782446-C-T SLC22A8 c.1-16G>A - 5-UTRSNV 2/11 -
13-95815535-A-G ABCC4 c.2214-65T>C - IntronicSNV - 17/30
7-99312378-T-A CYP3A7 c.671-73A>T - IntronicSNV - 7/12
4-89015857-C-T ABCG2 c.1738-46G>A - IntronicSNV - 14/15
17-61566085-G-C ACE c.2382G>C p.Ala794Ala Synonymous 16/25 -
6-31324741-G-C HLA-B c.74-7C>G - IntronicSNV - 1/7
3-121643120-C-A SLC15A2 c.1003-78C>A - IntronicSNV - 11/21
6-31324741-G-T HLA-B c.74-7C>A - IntronicSNV - 1/7
11-62782446-C-G SLC22A8 c.1-16G>C - 5-UTRSNV 2/11 -
13-95815535-A-T ABCC4 c.2214-65T>A - IntronicSNV - 17/30
6-31324270-G-T HLA-B c.344-51C>A - IntronicSNV - 2/7
6-31324270-G-A HLA-B c.344-51C>T - IntronicSNV - 2/7
22-42524947-C-T CYP2D6 c.506-1G>A - IntronicSNV - 3/8
10-101595975-G-A ABCC2 c.3542G>A p.Arg1181Gln Missense 25/32 -
20-61289938-G-A SLCO4A1 c.797-91G>A - IntronicSNV - 2/11
1-171178090-T-C FMO2 c.1414T>C - Missense 9/9 -
6-31324206-G-C HLA-B c.357C>G p.Leu119Leu Synonymous 3/8 -
6-31324206-G-T HLA-B c.357C>A p.Leu119Leu Synonymous 3/8 -
4-89018565-A-G ABCG2 c.1647+40T>C - IntronicSNV - 13/15
1-171174762-G-C FMO2 c.1172G>C p.Arg391Thr Missense 7/9 -
6-43400691-C-T ABCC10 c.844C>T p.Leu282Phe Missense 1/20 -
10-96824406-C-A CYP2C8 c.642+151G>T - IntronicSNV - 4/8
6-31239829-C-T HLA-C c.20G>A p.Arg7Gln Missense 1/8 -
1-67487109-T-C SLC35D1 c.797+109A>G - IntronicSNV - 9/11
5-156479509-A-G HAVCR1 c.536T>C p.Leu179Pro Missense 3/8 -
10-101610455-G-A ABCC2 c.4410G>A p.Glu1470Glu Synonymous 31/32 -
8-18079577-T-G NAT1 c.21T>G p.Leu7Leu Synonymous 3/3 -
3-121659197-G-T SLC15A2 c.1909-34G>T - IntronicSNV - 20/21
12-21014030-A-G SLCO1B3 c.439A>G p.Thr147Ala Missense 6/16 -
7-99319792-C-A CYP3A7 c.218+127G>T - IntronicSNV - 3/12
12-21014030-A-C SLCO1B3 c.439A>C p.Thr147Pro Missense 6/16 -
22-42522613-G-C CYP2D6 c.1457C>G p.Thr486Ser Missense 9/9 -
6-31324100-G-T HLA-B c.463C>A p.Arg155Ser Missense 3/8 -
6-31324100-G-A HLA-B c.463C>T p.Arg155Cys Missense 3/8 -
5-156479426-T-C HAVCR1 c.619A>G p.Thr207Ala Missense 3/8 -
1-67516316-T-A SLC35D1 c.393-129A>T - IntronicSNV - 4/11
1-161199781-C-T NR1I3 c.933-219G>A - IntronicSNV - 8/8
6-31237463-C-T HLA-C c.1016-161G>A - IntronicSNV - 5/7
6-31237254-C-T HLA-C c.1048+16G>A - IntronicSNV - 6/7
1-98060579-T-A DPYD c.958+36A>T - IntronicSNV - 9/22
15-75015410-G-A CYP1A1 c.29C>T p.Thr10Met Missense 2/7 -
6-160557569-C-T SLC22A1 c.955-7C>T - IntronicSNV - 5/10
10-101590538-G-A ABCC2 c.2813G>A p.Ser938Asn Missense 21/32 -
7-99272310-G-A CYP3A5 c.166-102C>T - IntronicSNV - 2/12
22-25011124-G-T GGT1 c.382+30G>T - IntronicSNV - 7/15
10-96827150-C-T CYP2C8 c.332-36G>A - IntronicSNV - 2/8
6-31237463-C-G HLA-C c.1016-161G>C - IntronicSNV - 5/7
10-96541616-G-C CYP2C19 c.681G>C p.Pro227Pro Synonymous 5/9 -
6-31324023-C-G HLA-B c.540G>C p.Arg180Arg Synonymous 3/8 -
6-31324077-C-G HLA-B c.486G>C p.Thr162Thr Synonymous 3/8 -
6-31324077-C-A HLA-B c.486G>T p.Thr162Thr Synonymous 3/8 -
8-18077126-G-T NAT1 c.1-2431G>T - IntronicSNV - 1/2
15-75015193-G-T CYP1A1 c.246C>A p.Pro82Pro Synonymous 2/7 -
15-75015193-G-A CYP1A1 c.246C>T p.Pro82Pro Synonymous 2/7 -
15-75015193-G-C CYP1A1 c.246C>G p.Pro82Pro Synonymous 2/7 -
10-101563815-G-A ABCC2 c.1249G>A p.Val417Ile Missense 10/32 -
4-155525545-A-T FGG c.*441T>A - IntergenicSNV 9/9 -
1-97544771-T-A DPYD c.2908-69A>T - IntronicSNV - 22/22
1-97544771-T-C DPYD c.2908-69A>G - IntronicSNV - 22/22
6-31237987-C-A HLA-C c.895G>T p.Glu299* Nonsense 4/8 -
6-31237987-C-G HLA-C c.895G>C p.Glu299Gln Missense 4/8 -
6-31237987-C-T HLA-C c.895G>A p.Glu299Lys Missense 4/8 -
6-31237230-A-T HLA-C c.1048+40T>A - IntronicSNV - 6/7
6-31322459-T-C HLA-B c.1013-17A>G - IntronicSNV - 5/7
11-62748416-G-A SLC22A6 c.1037+41C>T - IntronicSNV - 6/9
11-62782278-C-T SLC22A8 c.153G>A p.Pro51Pro Synonymous 2/11 -
15-75015410-G-C CYP1A1 c.29C>G p.Thr10Arg Missense 2/7 -
11-62748601-G-A SLC22A6 c.922-29C>T - IntronicSNV - 5/9
11-62748601-G-C SLC22A6 c.922-29C>G - IntronicSNV - 5/9
13-95696129-A-T ABCC4 c.3630-88T>A - IntronicSNV - 28/30
6-31323953-C-T HLA-B c.610G>A p.Glu204Lys Missense 3/8 -
6-31323953-C-G HLA-B c.610G>C p.Glu204Gln Missense 3/8 -
6-31323953-C-A HLA-B c.610G>T p.Glu204* Nonsense 3/8 -
15-92638193-G-C SLCO3A1 c.729G>C p.Ala243Ala Synonymous 3/10 -
15-92638193-G-A SLCO3A1 c.729G>A p.Ala243Ala Synonymous 3/10 -
15-92638193-G-T SLCO3A1 c.729G>T p.Ala243Ala Synonymous 3/10 -
6-31322487-G-A HLA-B c.1013-45C>T - IntronicSNV - 5/7
1-67507914-C-G SLC35D1 c.729+5G>C - IntronicSNV - 8/11
11-64332009-C-T SLC22A11 c.942+109C>T - IntronicSNV - 5/9
6-31324208-G-C HLA-B c.355C>G p.Leu119Val Missense 3/8 -
7-87178626-C-T ABCB1 c.1725+38G>A - IntronicSNV - 15/28
6-31239653-C-A HLA-C c.74-8G>T - IntronicSNV - 1/7
10-135350643-C-T CYP2E1 c.1044C>T p.Pro348Pro Synonymous 7/9 -
10-135350643-C-G CYP2E1 c.1044C>G p.Pro348Pro Synonymous 7/9 -
8-18257916-C-G NAT2 c.403C>G p.Leu135Val Missense 2/2 -
6-31239653-C-G HLA-C c.74-8G>C - IntronicSNV - 1/7
6-31239653-C-T HLA-C c.74-8G>A - IntronicSNV - 1/7
17-61558448-C-G ACE c.848-4C>G - IntronicSNV - 5/24
7-99269401-A-C CYP3A5 c.318+802T>G - IntronicSNV - 4/12
7-99375790-A-G CYP3A4 c.166-87T>C - IntronicSNV - 2/12
15-75012940-G-A CYP1A1 c.1429C>T p.Arg477Trp Missense 7/7 -
15-75012940-G-C CYP1A1 c.1429C>G p.Arg477Gly Missense 7/7 -
10-96798695-C-A CYP2C8 c.1250G>T p.Gly417Val Missense 8/9 -
3-121646641-A-G SLC15A2 c.1161A>G p.Ala387Ala Synonymous 14/22 -
10-96798695-C-T CYP2C8 c.1250G>A p.Gly417Asp Missense 8/9 -
6-31237513-T-C HLA-C c.1016-211A>G - IntronicSNV - 5/7
12-21294293-T-G SLCO1B1 c.1-216T>G - IntronicSNV - 1/14
12-21471732-A-G SLCO1A2 c.186T>C p.Asn62Asn Synonymous 2/14 -
6-160543329-G-GG SLC22A1 c.362_362dup p.Cys121Trpfs*8 Frameshift 1/11 -
15-92671801-C-A SLCO3A1 c.1512+82C>A - IntronicSNV - 7/9
20-61298952-G-A SLCO4A1 c.1473-145G>A - IntronicSNV - 7/11
13-95818445-G-A ABCC4 c.2001C>T p.Pro667Pro Synonymous 15/31 -
13-95839024-A-G ABCC4 c.1476T>C p.Asn492Asn Synonymous 11/31 -
8-27466315-T-C CLU c.246+140A>G - IntronicSNV - 3/8
1-67519422-G-A SLC35D1 c.203+72C>T - IntronicSNV - 1/11
5-156456902-C-G HAVCR1 c.987-50G>C - IntronicSNV - 7/7
12-21030672-A-T SLCO1B3 c.971-34A>T - IntronicSNV - 9/15
3-133692497-A-G SLCO2A1 c.397+10T>C - IntronicSNV - 3/13
6-31237162-C-G HLA-C c.1049G>C p.Cys350Ser Missense 7/8 -
3-121643804-C-T SLC15A2 c.1048C>T p.Leu350Phe Missense 13/22 -
3-121643804-C-G SLC15A2 c.1048C>G p.Leu350Val Missense 13/22 -
12-21015610-A-G SLCO1B3 c.629-80A>G - IntronicSNV - 7/15
3-119529104-G-C NR1I2 c.331+63G>C - IntronicSNV - 3/8
6-31239614-G-T HLA-C c.105C>A p.Ala35Ala Synonymous 2/8 -
6-31239614-G-A HLA-C c.105C>T p.Ala35Ala Synonymous 2/8 -
8-18080333-T-C NAT1 c.777T>C p.Ser259Ser Synonymous 3/3 -
3-119529104-G-A NR1I2 c.331+63G>A - IntronicSNV - 3/8
8-18080333-T-G NAT1 c.777T>G p.Ser259Arg Missense 3/3 -
10-101571442-G-T ABCC2 c.1967+83G>T - IntronicSNV - 15/31
10-101571442-G-A ABCC2 c.1967+83G>A - IntronicSNV - 15/31
22-25016311-G-A GGT1 c.399G>A p.Ala133Ala Synonymous 8/16 -
16-28619866-C-T SULT1A1 c.207G>A p.Lys69Lys Synonymous 3/8 -
15-90346645-C-T ANPEP c.1503+28G>A - IntronicSNV - 9/20
15-92694174-A-G SLCO3A1 c.1689-6A>G - IntronicSNV - 8/9
15-90346645-C-A ANPEP c.1503+28G>T - IntronicSNV - 9/20
7-99264352-A-G CYP3A5 c.433-40T>C - IntronicSNV - 5/12
3-121648102-G-A SLC15A2 c.1507-47G>A - IntronicSNV - 16/21
13-95839008-T-C ABCC4 c.1492A>G p.Lys498Glu Missense 11/31 -
7-99359812-T-C CYP3A4 c.1102A>G p.Ile368Val Missense 11/13 -
1-171173242-T-C FMO2 c.827+39T>C - IntronicSNV - 6/8
1-67487401-G-C SLC35D1 c.730-116C>G - IntronicSNV - 8/11
6-31324271-A-C HLA-B c.344-52T>G - IntronicSNV - 2/7
1-161199805-A-G NR1I3 c.933-243T>C - IntronicSNV - 8/8
1-171168585-A-T FMO2 c.585A>T p.Ser195Ser Synonymous 5/9 -
1-171168585-A-G FMO2 c.585A>G p.Ser195Ser Synonymous 5/9 -
6-160543123-T-C SLC22A1 c.156T>C p.Ser52Ser Synonymous 1/11 -
6-31322197-T-C HLA-B c.*63A>G - IntronicSNV - 7/7
10-96805788-T-A CYP2C8 c.820-80A>T - IntronicSNV - 5/8
1-171080080-G-A FMO3 c.769G>A p.Val257Met Missense 6/9 -
1-171168709-G-C FMO2 c.627+82G>C - IntronicSNV - 5/8
1-67474977-C-T SLC35D1 c.877-127G>A - IntronicSNV - 10/11
22-42457091-A-C NAGA c.958-20T>G - IntronicSNV - 7/8
1-171061990-A-G FMO3 c.132+59A>G - IntronicSNV - 2/8
2-234676412-CT-TC UGT1A1 c.997-83_997-82delinsTC - IntronicBlockSubstitution - 2/4
6-31322402-C-T HLA-B c.1045+8G>A - IntronicSNV - 6/7
5-101582984-C-T SLCO4C1 c.1783G>A p.Gly595Ser Missense 10/13 -
13-95715014-A-G ABCC4 c.3310T>C p.Leu1104Leu Synonymous 26/31 -
11-64332862-A-C SLC22A11 c.1058+53A>C - IntronicSNV - 6/9
13-95696252-C-G ABCC4 c.3630-211G>C - IntronicSNV - 28/30
1-110231572-A-C GSTM1 c.178-98A>C - IntronicSNV - 3/7
19-41350648-A-G CYP2A6 c.1191T>C p.Ser397Ser Synonymous 8/9 -
10-101606683-G-A ABCC2 c.4147-35G>A - IntronicSNV - 29/31
1-171174635-A-G FMO2 c.1045A>G p.Met349Val Missense 7/9 -
3-119526056-T-C NR1I2 c.1-42T>C - IntronicSNV - 1/8
8-27462369-G-A CLU c.829+72C>T - IntronicSNV - 5/8
7-87225281-C-A ABCB1 c.69-151G>T - IntronicSNV - 3/28
1-171168693-C-T FMO2 c.627+66C>T - IntronicSNV - 5/8
1-98186465-G-C DPYD c.483+601C>G - IntronicSNV - 5/22
11-64334968-G-A SLC22A11 c.1059-103G>A - IntronicSNV - 6/9
4-89028478-T-A ABCG2 c.1195-60A>T - IntronicSNV - 9/15
12-21015243-C-G SLCO1B3 c.482-103C>G - IntronicSNV - 6/15
4-89028478-T-C ABCG2 c.1195-60A>G - IntronicSNV - 9/15
16-55866915-C-T CES1 c.52+1G>A - IntronicSNV - 1/13
3-119535884-A-G NR1I2 c.1161-31A>G - IntronicSNV - 8/8
10-96802598-A-C CYP2C8 c.1149+49T>G - IntronicSNV - 7/8
7-99312378-T-C CYP3A7 c.671-73A>G - IntronicSNV - 7/12
5-156459856-C-T HAVCR1 c.986+9G>A - IntronicSNV - 7/7
7-87195616-G-A ABCB1 c.531-59C>T - IntronicSNV - 7/28
6-31322470-C-T HLA-B c.1013-28G>A - IntronicSNV - 5/7
17-61564052-A-G ACE c.2193A>G p.Ala731Ala Synonymous 14/25 -
20-61287700-T-C SLCO4A1 c.1-107T>C - IntronicSNV - 1/11
6-43413595-A-G ABCC10 c.3205A>G p.Ser1069Gly Missense 13/20 -
1-171174365-C-G FMO2 c.828-53C>G - IntronicSNV - 6/8
7-87165701-G-T ABCB1 c.2481+73C>A - IntronicSNV - 21/28
13-95815804-A-G ABCC4 c.2213+60T>C - IntronicSNV - 17/30
1-98293821-C-T DPYD c.151-69G>A - IntronicSNV - 2/22
19-41350489-C-G CYP2A6 c.1303+47G>C - IntronicSNV - 8/8
6-31237014-G-A HLA-C c.1097-64C>T - IntronicSNV - 7/7
5-101606170-T-A SLCO4C1 c.802+158A>T - IntronicSNV - 3/12
2-234676413-T-C UGT1A1 c.997-82T>C - IntronicSNV - 2/4
12-21448741-A-G SLCO1A2 c.1076-15T>C - IntronicSNV - 8/13
17-61559244-C-T ACE c.1118+145C>T - IntronicSNV - 7/24
10-96609775-A-C CYP2C19 c.1251A>C p.Gly417Gly Synonymous 8/9 -
3-133748763-G-C SLCO2A1 c.1-117C>G - 5-UTRSNV 1/14 -
1-171083012-C-G FMO3 c.828-135C>G - IntronicSNV - 6/8
1-171174365-C-T FMO2 c.828-53C>T - IntronicSNV - 6/8
7-87165701-G-A ABCB1 c.2481+73C>T - IntronicSNV - 21/28
10-101572880-C-A ABCC2 c.2073C>A p.Val691Val Synonymous 16/32 -
1-171251196-A-G FMO1 c.907A>G p.Ile303Val Missense 7/9 -
19-41350587-T-C CYP2A6 c.1252A>G p.Asn418Asp Missense 8/9 -
22-25019781-C-T GGT1 c.918C>T p.Pro306Pro Synonymous 11/16 -
6-31237766-A-T HLA-C c.992T>A p.Met331Lys Missense 5/8 -
12-21377806-T-C SLCO1B1 c.1865+33T>C - IntronicSNV - 14/14
15-75041917-C-A CYP1A2 c.1-163C>A - IntronicSNV - 1/6
1-98165030-T-C DPYD c.557A>G p.Tyr186Cys Missense 6/23 -
10-96612473-A-G CYP2C19 c.1292-17A>G - IntronicSNV - 8/8
10-135345675-G-A CYP2E1 c.535G>A p.Val179Ile Missense 4/9 -
3-121643699-G-A SLC15A2 c.1036-93G>A - IntronicSNV - 12/21
11-64332861-C-A SLC22A11 c.1058+52C>A - IntronicSNV - 6/9
17-61571471-G-T ACE c.3281+44G>T - IntronicSNV - 21/24
13-95816860-G-A ABCC4 c.2035-88C>T - IntronicSNV - 15/30
3-42916240-G-A CYP8B1 c.1069C>T p.Leu357Phe Missense 1/1 -
1-171155103-C-T FMO2 c.132+119C>T - IntronicSNV - 2/8
15-92671801-C-T SLCO3A1 c.1512+82C>T - IntronicSNV - 7/9
20-61289821-G-C SLCO4A1 c.797-208G>C - IntronicSNV - 2/11
8-18077007-G-C NAT1 c.-7+9G>C - intron_variant - 2/2
1-97770920-C-T DPYD c.2194G>A p.Val732Ile Missense 18/23 -
3-121643699-G-C SLC15A2 c.1036-93G>C - IntronicSNV - 12/21
17-61568594-A-G ACE c.2764A>G p.Lys922Glu Missense 19/25 -
1-171168545-T-C FMO2 c.545T>C p.Phe182Ser Missense 5/9 -
11-62760748-G-T SLC22A8 c.1590C>A p.Ile530Ile Synonymous 11/11 -
17-61571471-G-A ACE c.3281+44G>A - IntronicSNV - 21/24
6-160543220-C-T SLC22A1 c.253C>T p.Leu85Phe Missense 1/11 -
6-160543220-C-G SLC22A1 c.253C>G p.Leu85Val Missense 1/11 -
11-62760973-G-A SLC22A8 c.1452C>T p.Leu484Leu Synonymous 10/11 -
6-31237017-C-T HLA-C c.1097-67G>A - IntronicSNV - 7/7
6-43412865-T-C ABCC10 c.2759T>C p.Ile920Thr Missense 12/20 -
10-96701854-C-A CYP2C9 c.331+77C>A - IntronicSNV - 2/8
10-96701854-C-T CYP2C9 c.331+77C>T - IntronicSNV - 2/8
20-61296364-C-T SLCO4A1 c.1200C>T p.Thr400Thr Synonymous 6/12 -
6-43415429-C-T ABCC10 c.3629C>T p.Thr1210Ile Missense 16/20 -
20-61297601-G-A SLCO4A1 c.1277-131G>A - IntronicSNV - 6/11
11-64331731-G-C SLC22A11 c.822-49G>C - IntronicSNV - 4/9
19-41355738-C-T CYP2A6 c.328G>A p.Val110Ile Missense 2/9 -
19-41355738-C-G CYP2A6 c.328G>C p.Val110Leu Missense 2/9 -
5-156479425-G-A HAVCR1 c.620C>T p.Thr207Ile Missense 3/8 -
7-99306685-C-G CYP3A7 c.1226G>C p.Arg409Thr Missense 11/13 -
1-171173121-C-T FMO2 c.745C>T p.Arg249* Nonsense 6/9 -
1-98293842-T-G DPYD c.151-90A>C - IntronicSNV - 2/22
12-21391976-A-C SLCO1B1 c.1929A>C p.Leu643Phe Missense 15/15 -
16-28617485-C-G SULT1A1 c.667G>C p.Val223Leu Missense 7/8 -
16-28617485-C-T SULT1A1 c.667G>A p.Val223Met Missense 7/8 -
6-31323875-C-T HLA-B c.619+69G>A - IntronicSNV - 3/7
6-31322209-A-T HLA-B c.*51T>A - IntronicSNV - 7/7
1-110230767-G-C GSTM1 c.37-25G>C - IntronicSNV - 1/7
1-110230767-G-A GSTM1 c.37-25G>A - IntronicSNV - 1/7
6-160543008-C-T SLC22A1 c.41C>T p.Ser14Phe Missense 1/11 -
6-160543008-C-G SLC22A1 c.41C>G p.Ser14Cys Missense 1/11 -
3-133692471-C-G SLCO2A1 c.397+36G>C - IntronicSNV - 3/13
11-64329649-G-A SLC22A11 c.652+19G>A - IntronicSNV - 3/9
8-27468141-T-G CLU c.1-53A>C - IntronicSNV - 1/8
8-27468141-T-C CLU c.1-53A>G - IntronicSNV - 1/8
3-133666152-A-G SLCO2A1 c.1243T>C p.Leu415Leu Synonymous 9/14 -
11-62752182-T-C SLC22A6 c.1-20A>G - 5-UTRSNV 1/10 -
12-21034017-A-T SLCO1B3 c.1497+63A>T - IntronicSNV - 12/15
11-74880856-C-A SLCO2B1 c.781+47C>A - IntronicSNV - 6/13
8-18074322-A-T NAT1 c.-85-2598A>T - intron_variant - 1/2
6-31324245-A-T HLA-B c.344-26T>A - IntronicSNV - 2/7
6-31324245-A-C HLA-B c.344-26T>G - IntronicSNV - 2/7
6-31324245-A-G HLA-B c.344-26T>C - IntronicSNV - 2/7
3-119528759-C-T NR1I2 c.198-149C>T - IntronicSNV - 2/8
1-161205570-A-C NR1I3 c.238+67T>G - IntronicSNV - 3/8
1-161205570-A-G NR1I3 c.238+67T>C - IntronicSNV - 3/8
10-96824738-A-T CYP2C8 c.482-21T>A - IntronicSNV - 3/8
17-61557200-C-T ACE c.582C>T p.Asn194Asn Synonymous 4/25 -
5-156484992-G-A HAVCR1 c.1-38C>T - 5-UTRSNV 1/8 -
6-31237660-A-G HLA-C c.1015+83T>C - IntronicSNV - 5/7
4-89022362-C-T ABCG2 c.1367+20G>A - IntronicSNV - 11/15
12-21353648-A-C SLCO1B1 c.1135+42A>C - IntronicSNV - 9/14
8-18257704-G-A NAT2 c.191G>A p.Arg64Gln Missense 2/2 -
5-156479524-G-T HAVCR1 c.521C>A p.Thr174Lys Missense 3/8 -
3-119501780-G-C NR1I2 c.-23+633G>C - intron_variant - 1/8
6-31322209-A-C HLA-B c.*51T>G - IntronicSNV - 7/7
6-31322209-A-G HLA-B c.*51T>C - IntronicSNV - 7/7
6-31324892-G-C HLA-B c.44C>G p.Ala15Gly Missense 1/8 -
3-133692471-C-T SLCO2A1 c.397+36G>A - IntronicSNV - 3/13
20-61303004-T-G SLCO4A1 c.2026-98T>G - IntronicSNV - 11/11
11-62752182-T-A SLC22A6 c.1-20A>T - 5-UTRSNV 1/10 -
6-31237876-A-C HLA-C c.896-14T>G - IntronicSNV - 4/7
11-74880856-C-T SLCO2B1 c.781+47C>T - IntronicSNV - 6/13
6-31324184-C-G HLA-B c.379G>C p.Val127Leu Missense 3/8 -
8-18074322-A-G NAT1 c.-85-2598A>G - intron_variant - 1/2
1-11805771-G-A AGTRAP c.28-89G>A - IntronicSNV - 1/4
6-160557408-G-C SLC22A1 c.954+42G>C - IntronicSNV - 5/10
10-135352490-C-T CYP2E1 c.*22C>T - 3-UTRSNV 9/9 -
1-161199704-C-T NR1I3 c.933-142G>A - IntronicSNV - 8/8
19-41349640-G-C CYP2A6 c.*61C>G - 3-UTRSNV 9/9 -
1-110233057-T-C GSTM1 c.457-19T>C - IntronicSNV - 6/7
6-31239585-C-T HLA-C c.134G>A p.Arg45His Missense 2/8 -
13-95735604-G-C ABCC4 c.2536-60C>G - IntronicSNV - 20/30
13-95735604-G-T ABCC4 c.2536-60C>A - IntronicSNV - 20/30
7-87225279-G-A ABCB1 c.69-149C>T - IntronicSNV - 3/28
10-101553259-C-T ABCC2 c.334-49C>T - IntronicSNV - 3/31
19-41509950-G-A CYP2B6 c.216G>A p.Pro72Pro Synonymous 2/9 -
19-41509950-G-C CYP2B6 c.216G>C p.Pro72Pro Synonymous 2/9 -
7-99365859-A-T CYP3A4 c.670+118T>A - IntronicSNV - 7/12
22-25011222-T-G GGT1 c.382+128T>G - IntronicSNV - 7/15
19-41349636-G-T CYP2A6 c.*65C>A - 3-UTRSNV 9/9 -
19-41349636-G-A CYP2A6 c.*65C>T - 3-UTRSNV 9/9 -
15-92459474-C-T SLCO3A1 c.432C>T p.Ala144Ala Synonymous 2/10 -
19-41349636-G-C CYP2A6 c.*65C>G - 3-UTRSNV 9/9 -
16-28617514-C-T SULT1A1 c.638G>A p.Arg213His Missense 7/8 -
3-133666333-G-T SLCO2A1 c.1106-44C>A - IntronicSNV - 8/13
9-130914170-C-T LCN2 c.356-15C>T - IntronicSNV - 3/6
8-18258279-A-G NAT2 c.766A>G p.Lys256Glu Missense 2/2 -
3-119526149-G-A NR1I2 c.52G>A p.Glu18Lys Missense 2/9 -
10-135345675-G-T CYP2E1 c.535G>T p.Val179Phe Missense 4/9 -
6-160560862-G-C SLC22A1 c.1239G>C p.Ala413Ala Synonymous 7/11 -
6-160560862-G-A SLC22A1 c.1239G>A p.Ala413Ala Synonymous 7/11 -
12-21329813-C-A SLCO1B1 c.463C>A p.Pro155Thr Missense 5/15 -
3-133667267-C-A SLCO2A1 c.1105+113G>T - IntronicSNV - 8/13
3-133667267-C-T SLCO2A1 c.1105+113G>A - IntronicSNV - 8/13
8-27457432-C-G CLU c.1029G>C p.Glu343Asp Missense 7/9 -
13-95726394-C-A ABCC4 c.2917+74G>T - IntronicSNV - 23/30
6-31322303-C-T HLA-B c.1046G>A p.Cys349Tyr Missense 7/8 -
17-61557822-C-T ACE c.780C>T p.Arg260Arg Synonymous 5/25 -
6-31324063-G-A HLA-B c.500C>T p.Thr167Ile Missense 3/8 -
7-17373771-G-T AHR c.908+33G>T - IntronicSNV - 7/10
5-156482101-A-T HAVCR1 c.379+111T>A - IntronicSNV - 2/7
9-130914170-C-G LCN2 c.356-15C>G - IntronicSNV - 3/6
9-130914170-C-A LCN2 c.356-15C>A - IntronicSNV - 3/6
5-156479600-T-C HAVCR1 c.445A>G p.Thr149Ala Missense 3/8 -
22-42463689-T-C NAGA c.324+80A>G - IntronicSNV - 3/8
22-42463689-T-G NAGA c.324+80A>C - IntronicSNV - 3/8
10-96748635-C-T CYP2C9 c.1323C>T p.Ala441Ala Synonymous 9/9 -
3-133667698-G-A SLCO2A1 c.940+39C>T - IntronicSNV - 7/13
3-133667698-G-T SLCO2A1 c.940+39C>A - IntronicSNV - 7/13
6-31237162-C-T HLA-C c.1049G>A p.Cys350Tyr Missense 7/8 -
15-90335788-C-T ANPEP c.2255G>A p.Ser752Asn Missense 17/21 -
13-95829870-T-C ABCC4 c.1727+91A>G - IntronicSNV - 13/30
6-31239430-C-T HLA-C c.289G>A p.Ala97Thr Missense 2/8 -
13-95847020-A-G ABCC4 c.1263+70T>C - IntronicSNV - 9/30
13-95847020-A-C ABCC4 c.1263+70T>G - IntronicSNV - 9/30
5-101576401-G-A SLCO4C1 c.1876+21C>T - IntronicSNV - 11/12
7-75614953-T-C POR c.1455T>C p.Ala485Ala Synonymous 13/16 -
10-101542578-C-T ABCC2 c.1-24C>T - 5-UTRSNV 1/32 -
3-119529104-G-T NR1I2 c.331+63G>T - IntronicSNV - 3/8
7-87138511-G-A ABCB1 c.3489+80C>T - IntronicSNV - 27/28
19-41350664-A-T CYP2A6 c.1175T>A p.Phe392Tyr Missense 8/9 -
19-41354036-G-A CYP2A6 c.654+88C>T - IntronicSNV - 4/8
1-171254485-A-G FMO1 c.1401A>G p.Pro467Pro Synonymous 9/9 -
6-160557724-C-T SLC22A1 c.1061+42C>T - IntronicSNV - 6/10
8-27467946-C-T CLU c.97+46G>A - IntronicSNV - 2/8
3-42916238-G-A CYP8B1 c.1071C>T p.Leu357Leu Synonymous 1/1 -
6-31237871-G-A HLA-C c.896-9C>T - IntronicSNV - 4/7
6-31239614-G-C HLA-C c.105C>G p.Ala35Ala Synonymous 2/8 -
10-96522645-T-C CYP2C19 c.168+15T>C - IntronicSNV - 1/8
5-156479508-CA-TGGAACAGTCGTTGTCATTG HAVCR1 c.536_537delinsCAATGACAACGACTGTTCCA p.Leu179delinsPrometthrthrthrvalpro MultiAAMissense 3/8 -
6-31323233-A-G HLA-B c.756T>C p.Thr252Thr Synonymous 4/8 -
1-171077201-T-C FMO3 c.485-19T>C - IntronicSNV - 4/8
7-87165734-G-A ABCB1 c.2481+40C>T - IntronicSNV - 21/28
4-155505241-A-C FGA c.*35T>G - 3-UTRSNV 6/6 -
3-121634425-T-G SLC15A2 c.620-38T>G - IntronicSNV - 6/21
5-156456731-G-T HAVCR1 c.*13C>A - 3-UTRSNV 8/8 -
1-171162438-C-A FMO2 c.133-36C>A - IntronicSNV - 2/8
5-156479568-C-T HAVCR1 c.477G>A p.Thr159Thr Synonymous 3/8 -
12-21349863-A-G SLCO1B1 c.728-17A>G - IntronicSNV - 7/14
4-155507658-C-A FGA c.923G>T p.Arg308Leu Missense 5/6 -
1-98386496-C-A DPYD c.1-18G>T - 5-UTRSNV 1/23 -
15-75043592-C-T CYP1A2 c.894C>T p.Ser298Ser Synonymous 3/7 -
15-75043592-C-A CYP1A2 c.894C>A p.Ser298Arg Missense 3/7 -
13-95860214-C-T ABCC4 c.786-35G>A - IntronicSNV - 6/30
7-87133470-T-A ABCB1 c.*89A>T - 3-UTRSNV 29/29 -
13-95829903-A-G ABCC4 c.1727+58T>C - IntronicSNV - 13/30
6-31322339-C-T HLA-B c.1046-36G>A - IntronicSNV - 6/7
7-99270318-G-A CYP3A5 c.219-16C>T - IntronicSNV - 3/12
8-27468005-G-A CLU c.84C>T p.Asp28Asp Synonymous 2/9 -
1-161199656-G-A NR1I3 c.933-94C>T - IntronicSNV - 8/8
21-43733568-C-G TFF3 c.271+27G>C - IntronicSNV - 2/2
4-155526231-G-A FGG c.1130-13C>T - IntronicSNV - 8/8
7-99245914-A-G CYP3A5 c.*14T>C - 3-UTRSNV 13/13 -
10-101604006-A-G ABCC2 c.3844-73A>G - IntronicSNV - 27/31
6-31324820-G-T HLA-B c.73+43C>A - IntronicSNV - 1/7
6-31324938-C-T HLA-B c.1-3G>A - 5-UTRSNV 1/8 -
10-101605503-C-T ABCC2 c.4110C>T p.Leu1370Leu Synonymous 29/32 -
19-41352840-G-A CYP2A6 c.771C>T p.Arg257Arg Synonymous 5/9 -
19-41352840-G-T CYP2A6 c.771C>A p.Arg257Arg Synonymous 5/9 -
5-156479478-G-A HAVCR1 c.567C>T p.Ser189Ser Synonymous 3/8 -
6-31324742-T-A HLA-B c.74-8A>T - IntronicSNV - 1/7
15-90342845-C-T ANPEP c.1820-55G>A - IntronicSNV - 12/20
12-21428093-G-A SLCO1A2 c.1675+201C>T - IntronicSNV - 12/13
16-28618071-C-T SULT1A1 c.594+11G>A - IntronicSNV - 6/7
6-160552978-G-A SLC22A1 c.516-286G>A - IntronicSNV - 2/10
1-171083149-T-C FMO3 c.830T>C p.Val277Ala Missense 7/9 -
1-171086184-T-C FMO3 c.1257-56T>C - IntronicSNV - 8/8
12-21011310-T-C SLCO1B3 c.227-63T>C - IntronicSNV - 4/15
10-101563785-C-T ABCC2 c.1219C>T p.Leu407Leu Synonymous 10/32 -
15-92647304-G-A SLCO3A1 c.746-205G>A - IntronicSNV - 3/9
15-92459187-T-C SLCO3A1 c.181-36T>C - IntronicSNV - 1/9
15-92459187-T-G SLCO3A1 c.181-36T>G - IntronicSNV - 1/9
3-121650637-A-G SLC15A2 c.1761+55A>G - IntronicSNV - 19/21
6-160557643-C-G SLC22A1 c.1022C>G p.Pro341Arg Missense 6/11 -
6-43402565-G-T ABCC10 c.1458G>T p.Gly486Gly Synonymous 2/20 -
7-99365943-C-A CYP3A4 c.670+34G>T - IntronicSNV - 7/12
7-99365943-C-G CYP3A4 c.670+34G>C - IntronicSNV - 7/12
13-95899354-A-G ABCC4 c.186-5T>C - IntronicSNV - 2/30
4-89015857-C-A ABCG2 c.1738-46G>T - IntronicSNV - 14/15
1-67487401-G-T SLC35D1 c.730-116C>A - IntronicSNV - 8/11
6-31237255-G-A HLA-C c.1048+15C>T - IntronicSNV - 6/7
1-67487389-G-C SLC35D1 c.730-104C>G - IntronicSNV - 8/11
19-41350594-G-A CYP2A6 c.1245C>T p.His415His Synonymous 8/9 -
8-18257994-C-T NAT2 c.481C>T p.Leu161Leu Synonymous 2/2 -
15-92459187-T-A SLCO3A1 c.181-36T>A - IntronicSNV - 1/9
22-42466509-C-G NAGA c.1-208G>C - 5-UTRSNV 1/9 -
6-160557643-C-T SLC22A1 c.1022C>T p.Pro341Leu Missense 6/11 -
1-171077393-C-A FMO3 c.627+31C>A - IntronicSNV - 5/8
1-171077393-C-T FMO3 c.627+31C>T - IntronicSNV - 5/8
17-61556298-C-G ACE c.418-70C>G - IntronicSNV - 2/24
22-42463366-C-T NAGA c.325-72G>A - IntronicSNV - 3/8
1-67487407-G-A SLC35D1 c.730-122C>T - IntronicSNV - 8/11
1-67487407-G-C SLC35D1 c.730-122C>G - IntronicSNV - 8/11
1-67487407-G-T SLC35D1 c.730-122C>A - IntronicSNV - 8/11
11-74914226-C-T SLCO2B1 c.1829-126C>T - IntronicSNV - 12/13
3-121613361-T-C SLC15A2 c.38T>C p.Leu13Pro Missense 1/22 -
11-74914226-C-A SLCO2B1 c.1829-126C>A - IntronicSNV - 12/13
6-31239518-C-T HLA-C c.201G>A p.Pro67Pro Synonymous 2/8 -
3-119529025-C-T NR1I2 c.315C>T p.Ser105Ser Synonymous 3/9 -
6-31239518-C-G HLA-C c.201G>C p.Pro67Pro Synonymous 2/8 -
6-31324024-C-A HLA-B c.539G>T p.Arg180Leu Missense 3/8 -
19-41522870-C-A CYP2B6 c.*138C>A - 3-UTRSNV 9/9 -
10-96741058-C-A CYP2C9 c.1080C>A p.Asp360Glu Missense 7/9 -
21-43732425-C-T TFF3 c.272-46G>A - IntronicSNV - 2/2
19-41351267-C-T CYP2A6 c.1093G>A p.Val365Met Missense 7/9 -
1-11808706-T-A AGTRAP c.364+39T>A - IntronicSNV - 4/4
1-11808706-T-G AGTRAP c.364+39T>G - IntronicSNV - 4/4
4-155510536-C-T FGA c.180+53G>A - IntronicSNV - 2/5
1-11807426-C-T AGTRAP c.63-71C>T - IntronicSNV - 2/4
8-18077007-G-T NAT1 c.-7+9G>T - intron_variant - 2/2
6-31322197-T-A HLA-B c.*63A>T - IntronicSNV - 7/7
13-95714891-G-A ABCC4 c.3366+67C>T - IntronicSNV - 26/30
13-95714891-G-C ABCC4 c.3366+67C>G - IntronicSNV - 26/30
3-119501780-G-A NR1I2 c.-23+633G>A - intron_variant - 1/8
12-21015760-G-A SLCO1B3 c.699G>A p.Met233Ile Missense 8/16 -
10-135352490-C-A CYP2E1 c.*22C>A - 3-UTRSNV 9/9 -
10-135352490-C-G CYP2E1 c.*22C>G - 3-UTRSNV 9/9 -
15-90349558-C-T ANPEP c.257G>A p.Arg86Gln Missense 2/21 -
15-92459474-C-G SLCO3A1 c.432C>G p.Ala144Ala Synonymous 2/10 -
15-92459474-C-A SLCO3A1 c.432C>A p.Ala144Ala Synonymous 2/10 -
10-101544357-G-A ABCC2 c.34-8G>A - IntronicSNV - 1/31
11-74877004-G-A SLCO2B1 c.448+10G>A - IntronicSNV - 4/13
1-110230714-T-A GSTM1 c.37-78T>A - IntronicSNV - 1/7
10-101610488-C-G ABCC2 c.4443C>G p.Asn1481Lys Missense 31/32 -
6-31238009-T-A HLA-C c.873A>T p.Gln291His Missense 4/8 -
6-31238009-T-C HLA-C c.873A>G p.Gln291Gln Synonymous 4/8 -
6-31238009-T-G HLA-C c.873A>C p.Gln291His Missense 4/8 -
5-156479570-T-TTGT HAVCR1 c.476_477insAAC p.Thr160dupThr InFrameInsertion 3/8 -
10-101577035-T-A ABCC2 c.2095-30T>A - IntronicSNV - 16/31
19-41354553-C-A CYP2A6 c.459G>T p.Ala153Ala Synonymous 3/9 -
15-90348682-A-T ANPEP c.627T>A p.Thr209Thr Synonymous 3/21 -
3-119533865-G-A NR1I2 c.834G>A p.Gly278Gly Synonymous 6/9 -
10-96798548-C-T CYP2C8 c.1291+106G>A - IntronicSNV - 8/8
16-28617128-T-C SULT1A1 c.*14A>G - 3-UTRSNV 8/8 -
10-101610488-C-T ABCC2 c.4443C>T p.Asn1481Asn Synonymous 31/32 -
6-160575979-G-T SLC22A1 c.1498+37G>T - IntronicSNV - 9/10
17-61560033-G-A ACE c.1325G>A p.Arg442His Missense 8/25 -
17-61560033-G-C ACE c.1325G>C p.Arg442Pro Missense 8/25 -
17-61574662-C-T ACE c.3856C>T p.Arg1286Cys Missense 25/25 -
5-156479508-CA-TGGAACAGTCGTTGTCATTGGAACAGTCGTTGTCGTTG HAVCR1 c.536_537delinsCAACGACAACGACTGTTCCAATGACAACGACTGTTCCA p.Leu179delinsProthrthrthrthrvalprometthrthrthrvalpro MultiAAMissense 3/8 -
19-41356227-C-G CYP2A6 c.105G>C p.Pro35Pro Synonymous 1/9 -
19-41356227-C-T CYP2A6 c.105G>A p.Pro35Pro Synonymous 1/9 -
6-43403792-G-C ABCC10 c.1637-39G>C - IntronicSNV - 3/19
15-90341018-C-T ANPEP c.2010-65G>A - IntronicSNV - 14/20
6-43405613-C-T ABCC10 c.1792-59C>T - IntronicSNV - 4/19
10-101605550-G-T ABCC2 c.4146+11G>T - IntronicSNV - 29/31
22-25011109-A-C GGT1 c.382+15A>C - IntronicSNV - 7/15
22-42462084-A-G NAGA c.598-181T>C - IntronicSNV - 5/8
7-87160618-A-C ABCB1 c.2677T>G p.Ser893Ala Missense 22/29 -
10-101605550-G-C ABCC2 c.4146+11G>C - IntronicSNV - 29/31
6-160557646-G-A SLC22A1 c.1025G>A p.Arg342His Missense 6/11 -
4-155529851-A-C FGG c.667-49T>G - IntronicSNV - 6/8
6-43401027-A-G ABCC10 c.1180A>G p.Asn394Asp Missense 1/20 -
6-31239549-A-G HLA-C c.170T>C p.Phe57Ser Missense 2/8 -
6-31323203-A-G HLA-B c.786T>C p.Asp262Asp Synonymous 4/8 -
6-31239549-A-C HLA-C c.170T>G p.Phe57Cys Missense 2/8 -
19-41349943-G-C CYP2A6 c.1304-61C>G - IntronicSNV - 8/8
15-90344352-T-C ANPEP c.1809A>G p.Ile603Met Missense 12/21 -
19-41354553-C-T CYP2A6 c.459G>A p.Ala153Ala Synonymous 3/9 -
19-41354553-C-G CYP2A6 c.459G>C p.Ala153Ala Synonymous 3/9 -
7-99246026-A-G CYP3A5 c.1414-3T>C - IntronicSNV - 12/12
2-234676412-C-T UGT1A1 c.997-83C>T - IntronicSNV - 2/4
12-21349611-C-G SLCO1B1 c.728-269C>G - IntronicSNV - 7/14
4-155529851-A-T FGG c.667-49T>A - IntronicSNV - 6/8
1-67512920-A-C SLC35D1 c.636+28T>G - IntronicSNV - 7/11
6-31324847-C-G HLA-B c.73+16G>C - IntronicSNV - 1/7
1-67512920-A-T SLC35D1 c.636+28T>A - IntronicSNV - 7/11
6-31237061-C-A HLA-C c.1096+54G>T - IntronicSNV - 7/7
19-41515210-C-T CYP2B6 c.732C>T p.Tyr244Tyr Synonymous 5/9 -
19-41515952-G-T CYP2B6 c.876G>T p.Thr292Thr Synonymous 6/9 -
12-21294813-A-G SLCO1B1 c.84+221A>G - IntronicSNV - 2/14
6-31322987-C-T HLA-B c.909G>A p.Gln303Gln Synonymous 5/8 -
12-21015818-T-C SLCO1B3 c.727+30T>C - IntronicSNV - 8/15
15-90348538-C-A ANPEP c.757+14G>T - IntronicSNV - 3/20
15-92663905-C-T SLCO3A1 c.1174+46C>T - IntronicSNV - 5/9
16-28618237-TA-CG SULT1A1 c.499+34_499+35delinsCG - IntronicBlockSubstitution - 5/7
1-161202605-G-A NR1I3 c.540C>T p.Pro180Pro Synonymous 5/9 -
1-67519435-C-A SLC35D1 c.203+59G>T - IntronicSNV - 1/11
1-67474977-C-A SLC35D1 c.877-127G>T - IntronicSNV - 10/11
4-155525970-G-A FGG c.*16C>T - 3-UTRSNV 9/9 -
11-64323507-C-G SLC22A11 c.36C>G p.Gly12Gly Synonymous 1/10 -
11-64323507-C-T SLC22A11 c.36C>T p.Gly12Gly Synonymous 1/10 -
3-121613366-T-TT SLC15A2 c.43dupT p.Ser15Phefs*6 Frameshift 1/22 -
10-96829159-T-A CYP2C8 c.1A>T p.Met1Leu Missense 1/9 -
10-96829159-T-C CYP2C8 c.1A>G p.Met1Val Missense 1/9 -
3-121643303-T-A SLC15A2 c.1035+73T>A - IntronicSNV - 12/21
3-119501798-T-A NR1I2 c.-23+651T>A - intron_variant - 1/8
11-64335035-G-A SLC22A11 c.1059-36G>A - IntronicSNV - 6/9
5-156479572-A-T HAVCR1 c.473T>A p.Met158Lys Missense 3/8 -
6-31322229-A-C HLA-B c.*31T>G - IntronicSNV - 7/7
17-61564522-T-C ACE c.2305+88T>C - IntronicSNV - 15/24
1-110230628-C-T GSTM1 c.36+97C>T - IntronicSNV - 1/7
3-121641693-G-A SLC15A2 c.852G>A p.Ala284Ala Synonymous 9/22 -
22-25023213-G-A GGT1 c.1021-186G>A - IntronicSNV - 11/15
7-99269491-G-A CYP3A5 c.318+712C>T - IntronicSNV - 4/12
17-61562309-C-T ACE c.1922-288C>T - IntronicSNV - 12/24
3-121643170-A-C SLC15A2 c.1003-28A>C - IntronicSNV - 11/21
3-121643170-A-T SLC15A2 c.1003-28A>T - IntronicSNV - 11/21
17-61559923-C-T ACE c.1215C>T p.Pro405Pro Synonymous 8/25 -
1-171076888-G-T FMO3 c.394G>T p.Asp132Tyr Missense 4/9 -
12-21353317-T-G SLCO1B1 c.971-125T>G - IntronicSNV - 8/14
12-21294291-G-C SLCO1B1 c.1-218G>C - IntronicSNV - 1/14
5-101627435-C-T SLCO4C1 c.356-125G>A - IntronicSNV - 1/12
16-28618237-T-C SULT1A1 c.499+35A>G - IntronicSNV - 5/7
3-121641528-G-A SLC15A2 c.781-94G>A - IntronicSNV - 8/21
3-121641528-G-C SLC15A2 c.781-94G>C - IntronicSNV - 8/21
4-155505291-G-T FGA c.2586C>A p.Pro862Pro Synonymous 6/6 -
4-155505291-G-C FGA c.2586C>G p.Pro862Pro Synonymous 6/6 -
12-21011480-T-G SLCO1B3 c.334T>G p.Ser112Ala Missense 5/16 -
12-21011480-T-C SLCO1B3 c.334T>C p.Ser112Pro Missense 5/16 -
6-43414216-T-C ABCC10 c.3460+32T>C - IntronicSNV - 14/19
6-31323960-G-C HLA-B c.603C>G p.Asp201Glu Missense 3/8 -
6-31323960-G-A HLA-B c.603C>T p.Asp201Asp Synonymous 3/8 -
3-133670073-T-C SLCO2A1 c.840A>G p.Arg280Arg Synonymous 6/14 -
3-133670073-T-A SLCO2A1 c.840A>T p.Arg280Arg Synonymous 6/14 -
3-133698280-C-T SLCO2A1 c.234+45G>A - IntronicSNV - 2/13
3-133698280-C-A SLCO2A1 c.234+45G>T - IntronicSNV - 2/13
3-133698280-C-G SLCO2A1 c.234+45G>C - IntronicSNV - 2/13
11-62747083-G-C SLC22A6 c.1253-15C>G - IntronicSNV - 7/9
12-21051489-C-A SLCO1B3 c.1747+55C>A - IntronicSNV - 14/15
12-21051489-C-T SLCO1B3 c.1747+55C>T - IntronicSNV - 14/15
9-130913638-A-T LCN2 c.276-279A>T - IntronicSNV - 2/6
6-160560769-C-T SLC22A1 c.1146C>T p.Ser382Ser Synonymous 7/11 -
3-133692743-C-T SLCO2A1 c.235-74G>A - IntronicSNV - 2/13
1-171076888-G-C FMO3 c.394G>C p.Asp132His Missense 4/9 -
5-101631592-A-T SLCO4C1 c.355+20T>A - IntronicSNV - 1/12
15-90334146-G-A ANPEP c.2669+38C>T - IntronicSNV - 19/20
5-101631592-A-G SLCO4C1 c.355+20T>C - IntronicSNV - 1/12
15-90334146-G-T ANPEP c.2669+38C>A - IntronicSNV - 19/20
15-90334146-G-C ANPEP c.2669+38C>G - IntronicSNV - 19/20
2-234675829-C-T UGT1A1 c.996+18C>T - IntronicSNV - 2/4
1-98015269-G-A DPYD c.1371C>T p.Asn457Asn Synonymous 12/23 -
12-21294655-A-G SLCO1B1 c.84+63A>G - IntronicSNV - 2/14
21-43735529-T-C TFF3 c.1-3A>G - 5-UTRSNV 1/3 -
3-121648234-T-C SLC15A2 c.1553+39T>C - IntronicSNV - 17/21
17-61562774-T-A ACE c.2058+41T>A - IntronicSNV - 13/24
17-61562774-T-C ACE c.2058+41T>C - IntronicSNV - 13/24
17-61562774-T-G ACE c.2058+41T>G - IntronicSNV - 13/24
10-135352514-A-T CYP2E1 c.*46A>T - 3-UTRSNV 9/9 -
10-135352514-A-G CYP2E1 c.*46A>G - 3-UTRSNV 9/9 -
10-96535099-C-T CYP2C19 c.332-48C>T - IntronicSNV - 2/8
1-67512903-G-T SLC35D1 c.636+45C>A - IntronicSNV - 7/11
3-121643163-G-A SLC15A2 c.1003-35G>A - IntronicSNV - 11/21
3-121643163-G-C SLC15A2 c.1003-35G>C - IntronicSNV - 11/21
15-90328465-T-C ANPEP c.*115A>G - 3-UTRSNV 21/21 -
7-87229501-T-C ABCB1 c.1-1A>G - 5-UTRSNV 3/29 -
7-87135435-T-G ABCB1 c.3490-76A>C - IntronicSNV - 27/28
12-21459782-G-A SLCO1A2 c.442+34C>T - IntronicSNV - 4/13
12-21459782-G-T SLCO1A2 c.442+34C>A - IntronicSNV - 4/13
1-98015122-G-A DPYD c.1518C>T p.Tyr506Tyr Synonymous 12/23 -
19-41515813-C-T CYP2B6 c.823-86C>T - IntronicSNV - 5/8
6-43414234-G-T ABCC10 c.3460+50G>T - IntronicSNV - 14/19
15-92663630-A-G SLCO3A1 c.1010-65A>G - IntronicSNV - 4/9
10-101577018-G-A ABCC2 c.2095-47G>A - IntronicSNV - 16/31
6-43414234-G-C ABCC10 c.3460+50G>C - IntronicSNV - 14/19
6-43414234-G-A ABCC10 c.3460+50G>A - IntronicSNV - 14/19
6-31237727-T-C HLA-C c.1015+16A>G - IntronicSNV - 5/7
1-171251407-A-G FMO1 c.1118A>G p.Lys373Arg Missense 7/9 -
6-160553008-G-A SLC22A1 c.516-256G>A - IntronicSNV - 2/10
6-31237723-G-C HLA-C c.1015+20C>G - IntronicSNV - 5/7
13-95714976-C-G ABCC4 c.3348G>C p.Lys1116Asn Missense 26/31 -
13-95714976-C-T ABCC4 c.3348G>A p.Lys1116Lys Synonymous 26/31 -
15-90335243-A-G ANPEP c.2528+148T>C - IntronicSNV - 18/20
17-61574675-G-A ACE c.3869G>A p.Arg1290Gln Missense 25/25 -
1-98157362-G-A DPYD c.681-8C>T - IntronicSNV - 6/22
1-98157362-G-T DPYD c.681-8C>A - IntronicSNV - 6/22
1-97981242-T-C DPYD c.1740+40A>G - IntronicSNV - 13/22
12-21453424-G-A SLCO1A2 c.768C>T p.Asn256Asn Synonymous 7/14 -
8-18080312-A-T NAT1 c.756A>T p.Leu252Leu Synonymous 3/3 -
13-95839161-A-T ABCC4 c.1354-15T>A - IntronicSNV - 10/30
6-31324819-C-T HLA-B c.73+44G>A - IntronicSNV - 1/7
19-41356049-A-C CYP2A6 c.180+103T>G - IntronicSNV - 1/8
6-31324819-C-A HLA-B c.73+44G>T - IntronicSNV - 1/7
4-89020470-A-G ABCG2 c.1492+6T>C - IntronicSNV - 12/15
19-41356049-A-G CYP2A6 c.180+103T>C - IntronicSNV - 1/8
6-31237449-T-C HLA-C c.1016-147A>G - IntronicSNV - 5/7
6-31237449-T-G HLA-C c.1016-147A>C - IntronicSNV - 5/7
4-155511857-C-T FGA c.1-18G>A - 5-UTRSNV 1/6 -
5-156479524-G-A HAVCR1 c.521C>T p.Thr174Met Missense 3/8 -
5-156479524-G-C HAVCR1 c.521C>G p.Thr174Arg Missense 3/8 -
5-101627029-A-G SLCO4C1 c.619+18T>C - IntronicSNV - 2/12
3-121646759-G-A SLC15A2 c.1206+73G>A - IntronicSNV - 14/21
7-99277528-T-G CYP3A5 c.1-9A>C - 5-UTRSNV 1/13 -
15-92459486-C-G SLCO3A1 c.444C>G p.Asp148Glu Missense 2/10 -
10-96827485-G-A CYP2C8 c.169-37C>T - IntronicSNV - 1/8
15-92459486-C-T SLCO3A1 c.444C>T p.Asp148Asp Synonymous 2/10 -
1-67487376-C-A SLC35D1 c.730-91G>T - IntronicSNV - 8/11
1-67474880-T-C SLC35D1 c.877-30A>G - IntronicSNV - 10/11
11-64331701-C-T SLC22A11 c.822-79C>T - IntronicSNV - 4/9
5-156469572-T-C HAVCR1 c.837+66A>G - IntronicSNV - 5/7
6-31324200-G-T HLA-B c.363C>A p.Ser121Arg Missense 3/8 -
6-31324200-G-C HLA-B c.363C>G p.Ser121Arg Missense 3/8 -
6-31324200-G-A HLA-B c.363C>T p.Ser121Ser Synonymous 3/8 -
6-43401105-G-C ABCC10 c.1251+7G>C - IntronicSNV - 1/19
17-61566085-G-A ACE c.2382G>A p.Ala794Ala Synonymous 16/25 -
10-96698690-T-C CYP2C9 c.168+83T>C - IntronicSNV - 1/8
3-121643170-A-G SLC15A2 c.1003-28A>G - IntronicSNV - 11/21
17-61561017-C-T ACE c.1586+98C>T - IntronicSNV - 10/24
17-61573761-T-C ACE c.3387T>C p.Phe1129Phe Synonymous 23/25 -
6-31239449-C-A HLA-C c.270G>T p.Lys90Asn Missense 2/8 -
5-101585351-C-T SLCO4C1 c.1611G>A p.Arg537Arg Synonymous 9/13 -
15-90335256-T-C ANPEP c.2528+135A>G - IntronicSNV - 18/20
12-21422479-C-A SLCO1A2 c.*3G>T - 3-UTRSNV 14/14 -
10-96609568-T-C CYP2C19 c.1150-106T>C - IntronicSNV - 7/8
17-61557286-C-T ACE c.655+13C>T - IntronicSNV - 4/24
7-17373654-C-A AHR c.824C>A p.Pro275Gln Missense 7/11 -
16-28618072-G-A SULT1A1 c.594+10C>T - IntronicSNV - 6/7
6-31324829-G-T HLA-B c.73+34C>A - IntronicSNV - 1/7
12-21011296-A-T SLCO1B3 c.227-77A>T - IntronicSNV - 4/15
12-21011296-A-G SLCO1B3 c.227-77A>G - IntronicSNV - 4/15
6-31322395-A-G HLA-B c.1045+15T>C - IntronicSNV - 6/7
12-21036411-A-G SLCO1B3 c.1557A>G p.Ala519Ala Synonymous 13/16 -
6-31324895-G-T HLA-B c.41C>A p.Ser14* Nonsense 1/8 -
6-31324895-G-C HLA-B c.41C>G p.Ser14Trp Missense 1/8 -
20-61292537-G-A SLCO4A1 c.1121+10G>A - IntronicSNV - 5/11
1-97544695-T-C DPYD c.2915A>G p.Gln972Arg Missense 23/23 -
5-156479569-G-GCTG HAVCR1 c.476_477insAGC p.Thr159_thr160insAla InFrameInsertion 3/8 -
17-61556527-A-G ACE c.511+66A>G - IntronicSNV - 3/24
19-41355754-T-C CYP2A6 c.312A>G p.Gln104Gln Synonymous 2/9 -
17-61570863-C-T ACE c.2979C>T p.Ile993Ile Synonymous 20/25 -
22-25010885-G-A GGT1 c.295+12G>A - IntronicSNV - 6/15
6-31322395-A-T HLA-B c.1045+15T>A - IntronicSNV - 6/7
22-25010885-G-T GGT1 c.295+12G>T - IntronicSNV - 6/15
15-92705844-G-T SLCO3A1 c.1754-142G>T - IntronicSNV - 9/9
15-92705844-G-A SLCO3A1 c.1754-142G>A - IntronicSNV - 9/9
1-171174312-T-A FMO2 c.828-106T>A - IntronicSNV - 6/8
1-97547831-G-A DPYD c.2907+55C>T - IntronicSNV - 22/22
1-97547831-G-C DPYD c.2907+55C>G - IntronicSNV - 22/22
15-92647324-G-A SLCO3A1 c.746-185G>A - IntronicSNV - 3/9
1-171062005-G-T FMO3 c.132+74G>T - IntronicSNV - 2/8
4-155505692-C-G FGA c.2185G>C p.Glu729Gln Missense 6/6 -
12-21349885-A-G SLCO1B1 c.733A>G p.Ile245Val Missense 8/15 -
6-31238001-A-C HLA-C c.881T>G p.Leu294Arg Missense 4/8 -
6-31238001-A-G HLA-C c.881T>C p.Leu294Pro Missense 4/8 -
6-31238001-A-T HLA-C c.881T>A p.Leu294His Missense 4/8 -
6-31324202-T-C HLA-B c.361A>G p.Ser121Gly Missense 3/8 -
6-31324202-T-A HLA-B c.361A>T p.Ser121Cys Missense 3/8 -
7-87199564-C-A ABCB1 c.287-25G>T - IntronicSNV - 5/28
1-97839016-A-G DPYD c.2058+101T>C - IntronicSNV - 16/22
7-87199564-C-T ABCB1 c.287-25G>A - IntronicSNV - 5/28
15-90349461-G-T ANPEP c.354C>A p.Asp118Glu Missense 2/21 -
19-41356281-T-C CYP2A6 c.51A>G p.Val17Val Synonymous 1/9 -
20-61303154-C-T SLCO4A1 c.2078C>T p.Ser693Leu Missense 12/12 -
6-31237858-T-C HLA-C c.900A>G p.Pro300Pro Synonymous 5/8 -
7-99358615-G-A CYP3A4 c.1251-11C>T - IntronicSNV - 11/12
10-101556824-G-T ABCC2 c.633-30G>T - IntronicSNV - 6/31
3-119526349-G-A NR1I2 c.197+55G>A - IntronicSNV - 2/8
6-31237991-G-C HLA-C c.891C>G p.Ser297Arg Missense 4/8 -
7-87180198-C-T ABCB1 c.1000-44G>A - IntronicSNV - 10/28
1-98348885-G-A DPYD c.85C>T p.Arg29Cys Missense 2/23 -
6-31324227-C-G HLA-B c.344-8G>C - IntronicSNV - 2/7
12-21428062-C-T SLCO1A2 c.1675+232G>A - IntronicSNV - 12/13
6-31322340-G-T HLA-B c.1046-37C>A - IntronicSNV - 6/7
6-31322340-G-A HLA-B c.1046-37C>T - IntronicSNV - 6/7
6-31324227-C-A HLA-B c.344-8G>T - IntronicSNV - 2/7
5-101627435-C-G SLCO4C1 c.356-125G>C - IntronicSNV - 1/12
12-21377559-G-C SLCO1B1 c.1748-97G>C - IntronicSNV - 13/14
4-155505242-G-A FGA c.*34C>T - 3-UTRSNV 6/6 -
13-95748221-T-C ABCC4 c.2536-12677A>G - IntronicSNV - 20/30
9-130914353-T-C LCN2 c.475+49T>C - IntronicSNV - 4/6
10-96602622-C-T CYP2C19 c.990C>T p.Val330Val Synonymous 7/9 -
10-96829159-T-G CYP2C8 c.1A>C p.Met1Leu Missense 1/9 -
15-92647531-C-T SLCO3A1 c.768C>T p.Asp256Asp Synonymous 4/10 -
7-87225046-G-A ABCB1 c.117+36C>T - IntronicSNV - 4/28
7-87138532-A-C ABCB1 c.3489+59T>G - IntronicSNV - 27/28
10-96541538-T-C CYP2C19 c.643-40T>C - IntronicSNV - 4/8
1-171236840-C-G FMO1 c.291C>G p.His97Gln Missense 3/9 -
6-31324151-C-T HLA-B c.412G>A p.Asp138Asn Missense 3/8 -
1-11807459-G-A AGTRAP c.63-38G>A - IntronicSNV - 2/4
7-87179601-A-G ABCB1 c.1236T>C p.Gly412Gly Synonymous 13/29 -
3-119533773-T-C NR1I2 c.795-53T>C - IntronicSNV - 5/8
13-95861804-A-G ABCC4 c.669T>C p.Ile223Ile Synonymous 6/31 -
3-133657450-G-A SLCO2A1 c.1626-113C>T - IntronicSNV - 11/13
6-43413669-G-A ABCC10 c.3279G>A p.Gly1093Gly Synonymous 13/20 -
11-62748600-C-T SLC22A6 c.922-28G>A - IntronicSNV - 5/9
8-18257854-T-C NAT2 c.341T>C p.Ile114Thr Missense 2/2 -
5-101572549-C-A SLCO4C1 c.*13G>T - 3-UTRSNV 13/13 -
5-101572549-C-G SLCO4C1 c.*13G>C - 3-UTRSNV 13/13 -
19-41354496-C-A CYP2A6 c.493+23G>T - IntronicSNV - 3/8
17-61573760-T-TCA ACE c.3386_3387insCA p.Val1130Metfs*43 Frameshift 23/25 -
13-95815454-T-C ABCC4 c.2230A>G p.Met744Val Missense 18/31 -
6-160551092-G-A SLC22A1 c.412-44G>A - IntronicSNV - 1/10
10-101560106-C-T ABCC2 c.1032-37C>T - IntronicSNV - 8/31
22-25023207-G-A GGT1 c.1021-192G>A - IntronicSNV - 11/15
1-171177858-G-T FMO2 c.1257-75G>T - IntronicSNV - 8/8
15-90336373-T-G ANPEP c.2158-16A>C - IntronicSNV - 15/20
15-90336373-T-C ANPEP c.2158-16A>G - IntronicSNV - 15/20
3-133657450-G-T SLCO2A1 c.1626-113C>A - IntronicSNV - 11/13
6-160560845-A-C SLC22A1 c.1222A>C p.Met408Leu Missense 7/11 -
10-101560106-C-A ABCC2 c.1032-37C>A - IntronicSNV - 8/31
22-25010943-T-C GGT1 c.296-65T>C - IntronicSNV - 6/15
3-121647467-C-T SLC15A2 c.1341+65C>T - IntronicSNV - 15/21
6-31324003-T-C HLA-B c.560A>G p.Glu187Gly Missense 3/8 -
5-101574970-T-G SLCO4C1 c.1999A>C p.Met667Leu Missense 12/13 -
6-43412518-C-A ABCC10 c.2606-8C>A - IntronicSNV - 10/19
6-31324194-G-A HLA-B c.369C>T p.Tyr123Tyr Synonymous 3/8 -
4-89028544-A-G ABCG2 c.1195-126T>C - IntronicSNV - 9/15
4-89028544-A-C ABCG2 c.1195-126T>G - IntronicSNV - 9/15
19-41351963-G-A CYP2A6 c.871C>T p.Leu291Leu Synonymous 6/9 -
11-62782305-G-C SLC22A8 c.126C>G p.Ala42Ala Synonymous 2/11 -
11-62782305-G-A SLC22A8 c.126C>T p.Ala42Ala Synonymous 2/11 -
3-119526394-G-A NR1I2 c.197+100G>A - IntronicSNV - 2/8
1-171250008-A-G FMO1 c.711A>G p.Thr237Thr Synonymous 6/9 -
7-99361387-C-G CYP3A4 c.1023+91G>C - IntronicSNV - 10/12
15-90335733-C-T ANPEP c.2310G>A p.Glu770Glu Synonymous 17/21 -
11-64336361-G-T SLC22A11 c.1382+111G>T - IntronicSNV - 8/9
3-133673940-C-G SLCO2A1 c.495G>C p.Glu165Asp Missense 4/14 -
3-121613496-C-T SLC15A2 c.105+68C>T - IntronicSNV - 1/21
15-90335379-G-T ANPEP c.2528+12C>A - IntronicSNV - 18/20
5-101597815-T-C SLCO4C1 c.900-78A>G - IntronicSNV - 4/12
19-41354712-A-G CYP2A6 c.344-44T>C - IntronicSNV - 2/8
17-61562171-G-T ACE c.1921+269G>T - IntronicSNV - 12/24
17-61562171-G-A ACE c.1921+269G>A - IntronicSNV - 12/24
8-18258103-G-A NAT2 c.590G>A p.Arg197Gln Missense 2/2 -
10-135347397-T-G CYP2E1 c.963T>G p.Ile321Met Missense 6/9 -
10-135347397-T-C CYP2E1 c.963T>C p.Ile321Ile Synonymous 6/9 -
12-21015815-T-G SLCO1B3 c.727+27T>G - IntronicSNV - 8/15
19-41350507-T-C CYP2A6 c.1303+29A>G - IntronicSNV - 8/8
7-99366047-T-A CYP3A4 c.600A>T p.Gln200His Missense 7/13 -
17-61571836-C-T ACE c.3380+5C>T - IntronicSNV - 22/24
15-92690222-G-C SLCO3A1 c.1521G>C p.Thr507Thr Synonymous 8/10 -
15-92690222-G-A SLCO3A1 c.1521G>A p.Thr507Thr Synonymous 8/10 -
22-42456271-T-G NAGA c.*12A>C - 3-UTRSNV 9/9 -
6-43403393-C-T ABCC10 c.1480-96C>T - IntronicSNV - 2/19
8-27461773-A-G CLU c.934+35T>C - IntronicSNV - 6/8
5-101627414-A-T SLCO4C1 c.356-104T>A - IntronicSNV - 1/12
7-99319851-C-A CYP3A7 c.218+68G>T - IntronicSNV - 3/12