PMID: 31681433

Exome Sequencing in BRCA1- and BRCA2-Negative Greek Families Identifies MDM1 and NBEAL1 as Candidate Risk Genes for Hereditary Breast Cancer.

Frontiers in genetics

S Glentis, AC Dimopoulos, K Rouskas, G Ntritsos, E Evangelou, SA Narod, AM Mes-Masson, WD Foulkes, B Rivera, PN Tonin, J Ragoussis, AS Dimas

2019

1745 variants were identified in this publication

Variant ID	Gene	cDNA	Protein	Consequence	Exon	Intron
12-11083515-C-T	PRH2	c.355C>T	p.Arg119Cys	Missense	3/4	-
1-11298552-T-C	MTOR	c.1909A>G	p.Ile637Val	Missense	12/58	-
3-75787194-C-T	ZNF717	c.1580G>A	p.Arg527Lys	Missense	5/5	-
3-75787194-C-A	ZNF717	c.1580G>T	p.Arg527Ile	Missense	5/5	-
3-151171231-T-C	IGSF10	c.656A>G	p.Asn219Ser	Missense	3/6	-
12-11286486-G-T	TAS2R30	c.358C>A	p.Arg120Ser	Missense	1/1	-
12-11286486-G-A	TAS2R30	c.358C>T	p.Arg120Cys	Missense	1/1	-
2-160826659-C-T	PLA2R1	c.2660G>A	p.Arg887His	Missense	18/27	-
13-32890661-G-A	BRCA2	c.64G>A	p.Ala22Thr	Missense	2/27	-
2-186669745-C-A	FSIP2	c.15712C>A	-	missense_variant	17/23	-
X-107929290-C-T	COL4A5	c.4228C>T	p.Arg1410Cys	Missense	46/51	-
7-44610412-C-T	DDX56	c.955G>A	p.Val319Ile	Missense	7/14	-
19-8203392-G-A	FBN3	c.922C>T	p.Leu308Phe	Missense	9/64	-
19-8203392-G-C	FBN3	c.922C>G	p.Leu308Val	Missense	9/64	-
1-26608849-T-C	UBXN11	c.1405A>G	p.Ser469Gly	Missense	15/15	-
1-26608849-T-A	UBXN11	c.1405A>T	p.Ser469Cys	Missense	15/15	-
19-40928814-C-T	SERTAD1	c.640G>A	p.Glu214Lys	Missense	2/2	-
8-134251279-G-T	NDRG1	c.1027C>A	p.Arg343Ser	Missense	16/16	-
11-101832689-A-T	CEP126	c.923A>T	p.His308Leu	Missense	6/11	-
7-120979281-G-A	WNT16	c.980G>A	p.Arg327Gln	Missense	4/4	-
12-111317756-G-A	CCDC63	c.536G>A	p.Arg179Gln	Missense	6/12	-
5-72865362-G-A	UTP15	c.409G>A	p.Val137Met	Missense	5/13	-
6-17764793-C-T	KIF13A	c.4861G>A	p.Glu1621Lys	Missense	38/38	-
22-23915583-T-C	IGLL1	c.512A>G	p.Asn171Ser	Missense	3/3	-
5-132097207-C-T	SEPT8	c.905G>A	p.Arg302His	Missense	7/10	-
16-27761387-G-A	KIAA0556	c.3106G>A	p.Asp1036Asn	Missense	16/28	-
14-105415031-C-G	AHNAK2	c.6757G>C	p.Gly2253Arg	Missense	7/7	-
10-3183003-G-C	PITRM1	c.2650C>G	p.Leu884Val	Missense	24/27	-
19-42814791-G-A	PRR19	c.970G>A	p.Asp324Asn	Missense	3/3	-
17-7578250-T-C	TP53	c.599A>G	p.Asn200Ser	Missense	6/11	-
22-36900737-C-G	FOXRED2	c.604G>C	p.Glu202Gln	Missense	3/9	-
22-36900737-C-T	FOXRED2	c.604G>A	p.Glu202Lys	Missense	3/9	-
19-1455153-T-C	APC2	c.419T>C	p.Phe140Ser	Missense	5/15	-
1-109801345-C-T	CELSR2	c.3602C>T	p.Pro1201Leu	Missense	2/34	-
5-50125738-A-G	PARP8	c.2176A>G	p.Met726Val	Missense	22/26	-
2-96950323-C-T	SNRNP200	c.4165G>A	p.Val1389Ile	Missense	31/45	-
8-37794845-C-T	GOT1L1	c.469G>A	p.Asp157Asn	Missense	4/9	-
7-44148557-G-T	AEBP1	c.1000G>T	p.Glu334*	Nonsense	7/21	-
7-44148557-G-A	AEBP1	c.1000G>A	p.Glu334Lys	Missense	7/21	-
19-11106914-A-G	SMARCA4	c.1619A>G	p.Lys540Arg	Missense	10/35	-
19-48953603-G-A	GRWD1	c.502G>A	p.Val168Met	Missense	4/7	-
19-48953603-G-C	GRWD1	c.502G>C	p.Val168Leu	Missense	4/7	-
17-37873690-G-A	ERBB2	c.1855G>A	p.Glu619Lys	Missense	15/27	-
11-47303165-A-G	MADD	c.1330A>G	p.Asn444Asp	Missense	8/33	-
19-549171-C-T	GZMM	c.598C>T	p.Gln200*	Nonsense	4/5	-
17-37873579-G-A	ERBB2	c.1744G>A	p.Asp582Asn	Missense	15/27	-
1-20073703-C-T	TMCO4	c.566G>A	p.Arg189His	Missense	8/16	-
4-126373018-C-T	FAT4	c.10847C>T	p.Thr3616Met	Missense	9/17	-
1-117156600-T-C	IGSF3	c.619A>G	p.Ser207Gly	Missense	4/12	-
19-19645843-G-A	YJEFN3	c.319G>A	p.Ala107Thr	Missense	4/7	-
13-32899315-G-C	BRCA2	c.419G>C	p.Ser140Thr	Missense	4/27	-
7-151848538-G-T	KMT2C	c.12655C>A	p.Leu4219Ile	Missense	50/59	-
10-101557063-G-A	ABCC2	c.842G>A	p.Ser281Asn	Missense	7/32	-
17-79514675-T-C	FAAP100	c.1433A>G	p.Gln478Arg	Missense	5/9	-
4-39064647-T-A	KLHL5	c.375T>A	p.Ser125Arg	Missense	2/12	-
1-15655944-G-A	FHAD1	c.1813G>A	p.Val605Met	Missense	14/31	-
19-40580431-C-T	ZNF780A	c.1918G>A	p.Ala640Thr	Missense	6/6	-
19-40580431-C-A	ZNF780A	c.1918G>T	p.Ala640Ser	Missense	6/6	-
11-74203256-T-A	LIPT2	c.620A>T	p.Glu207Val	Missense	2/2	-
21-43161672-C-G	RIPK4	c.1681G>C	p.Val561Leu	Missense	8/8	-
21-43161672-C-T	RIPK4	c.1681G>A	p.Val561Met	Missense	8/8	-
6-30997667-A-G	MUC22	c.4459A>G	p.Thr1487Ala	Missense	3/5	-
7-43908448-G-A	URGCP-MRPS24	c.*137C>T	-	IntronicSNV	7/7	-
15-86801237-C-T	AGBL1	c.806C>T	p.Ser269Phe	Missense	8/25	-
2-239344354-G-A	ASB1	c.194G>A	p.Arg65His	Missense	3/5	-
7-94989379-C-G	PON3	c.971G>C	p.Gly324Ala	Missense	9/9	-
22-38119380-C-T	TRIOBP	c.817C>T	p.Arg273Cys	Missense	7/24	-
7-94989379-C-T	PON3	c.971G>A	p.Gly324Asp	Missense	9/9	-
16-71103393-G-A	HYDIN	c.1832C>T	p.Thr611Ile	Missense	14/19	-
16-71103393-G-T	HYDIN	c.1832C>A	p.Thr611Asn	Missense	14/19	-
6-43582176-C-A	POLH	c.2024C>A	p.Ser675Tyr	Missense	11/11	-
14-45579316-A-G	PRPF39	c.1196A>G	p.Asn399Ser	Missense	9/14	-
10-126691579-C-T	CTBP2	c.308G>A	p.Arg103Gln	Missense	5/11	-
3-48627789-C-A	COL7A1	c.1907G>T	p.Gly636Val	Missense	15/118	-
7-100645834-A-T	MUC12	c.11990A>T	p.His3997Leu	Missense	2/12	-
7-100645834-A-G	MUC12	c.11990A>G	p.His3997Arg	Missense	2/12	-
1-109811522-G-A	CELSR2	c.6523G>A	p.Asp2175Asn	Missense	19/34	-
6-152784621-T-C	SYNE1	c.1964A>G	p.Gln655Arg	Missense	19/146	-
1-117142860-C-T	IGSF3	c.1792G>A	p.Val598Met	Missense	8/12	-
17-21319792-G-A	KCNJ12	c.1138G>A	p.Glu380Lys	Missense	3/3	-
10-126683103-C-T	CTBP2	c.715G>A	p.Val239Ile	Missense	7/11	-
2-234115357-C-A	INPP5D	c.*3C>A	-	3_prime_UTR_variant	28/28	-
2-234115357-C-T	INPP5D	c.*3C>T	-	3_prime_UTR_variant	28/28	-
12-85674211-C-G	ALX1	c.172C>G	p.Arg58Gly	Missense	1/4	-
22-35802648-C-T	MCM5	c.526C>T	p.Arg176Cys	Missense	5/17	-
22-36681327-T-C	MYH9	c.5323A>G	p.Lys1775Glu	Missense	38/41	-
3-51661637-C-T	RAD54L2	c.208C>T	p.Arg70Trp	Missense	4/23	-
14-103998955-G-A	TRMT61A	c.368G>A	p.Arg123His	Missense	3/4	-
3-105378061-G-C	CBLB	c.2702C>G	p.Ala901Gly	Missense	19/19	-
15-86253813-C-T	AKAP13	c.5536C>T	p.Pro1846Ser	Missense	19/37	-
7-8196585-G-A	ICA1	c.804+161C>T	-	IntronicSNV	-	8/13
16-89985950-C-T	MC1R	c.284C>T	p.Thr95Met	Missense	1/1	-
20-43836956-A-G	SEMG1	c.1018A>G	p.Ser340Gly	Missense	2/3	-
14-105411680-C-G	AHNAK2	c.10108G>C	p.Gly3370Arg	Missense	7/7	-
3-195300740-C-G	APOD	c.226G>C	p.Val76Leu	Missense	3/5	-
2-30987041-G-A	CAPN13	c.656C>T	p.Ala219Val	Missense	6/23	-
13-32910701-G-A	BRCA2	c.2209G>A	p.Ala737Thr	Missense	11/27	-
13-32910417-TC-T	BRCA2	c.1925delC	p.Ser642Leufs*2	Frameshift	11/27	-
11-76888673-C-T	MYO7A	c.2266C>T	p.Arg756Trp	Missense	19/49	-
6-74481186-C-T	CD109	c.1709C>T	p.Pro570Leu	Missense	15/33	-
3-49365221-G-C	USP4	c.258C>G	p.His86Gln	Missense	3/21	-
17-72943253-G-A	OTOP3	c.1303G>A	p.Val435Met	Missense	6/7	-
17-37868666-T-A	ERBB2	c.1113T>A	p.Phe371Leu	Missense	9/27	-
19-52888358-C-T	ZNF880	c.1525C>T	p.Arg509*	Nonsense	4/4	-
4-90872862-C-A	MMRN1	c.3225C>A	p.Asn1075Lys	Missense	7/8	-
4-90872862-C-G	MMRN1	c.3225C>G	p.Asn1075Lys	Missense	7/8	-
X-140993674-G-T	MAGEC1	c.484G>T	p.Val162Phe	Missense	4/4	-
1-15642964-G-A	FHAD1	c.1260+1G>A	-	IntronicSNV	-	9/30
11-118133248-T-G	MPZL2	c.341A>C	p.Gln114Pro	Missense	3/6	-
4-187088399-G-T	FAM149A	c.1358G>T	p.Gly453Val	Missense	13/14	-
9-124072992-G-A	GSN	c.535G>A	p.Val179Met	Missense	4/17	-
19-549018-G-A	GZMM	c.445G>A	p.Gly149Ser	Missense	4/5	-
12-53453014-G-A	TNS2	c.1589G>A	p.Arg530Gln	Missense	18/29	-
14-68050566-C-T	PLEKHH1	c.3535C>T	p.Arg1179Cys	Missense	25/29	-
X-140993674-G-C	MAGEC1	c.484G>C	p.Val162Leu	Missense	4/4	-
2-242078172-A-G	PASK	c.638T>C	p.Val213Ala	Missense	5/18	-
3-188327604-C-G	LPP	c.1085C>G	p.Ala362Gly	Missense	6/11	-
17-7577146-TAG-TTT	TP53	c.790_792delCTAinsTTT	p.Leu264Phe	Missense	8/11	-
13-32903582-AGA-TGT	BRCA2	c.634_636delAGAinsTGT	p.Arg212Cys	Missense	8/27	-
19-47879329-A-G	DHX34	c.2456A>G	p.Asn819Ser	Missense	11/17	-
1-156926306-C-T	ARHGEF11	c.1577G>A	p.Arg526His	Missense	19/41	-
10-72468469-G-A	ADAMTS14	c.805G>A	p.Asp269Asn	Missense	4/22	-
18-44113283-G-A	LOXHD1	c.4217C>T	p.Ala1406Val	Missense	28/40	-
1-26142081-G-A	SELENON	c.1645G>A	p.Val549Met	Missense	13/13	-
17-37868610-GTG-ATC	ERBB2	c.1057_1059delGTGinsATC	p.Val353Ile	Missense	9/27	-
3-50327010-T-C	IFRD2	c.839A>G	p.Tyr280Cys	Missense	7/12	-
11-2192950-C-T	TH	c.67G>A	p.Ala23Thr	Missense	1/13	-
20-33588193-G-C	MYH7B	c.5005G>C	p.Gly1669Arg	Missense	39/45	-
20-33588193-G-A	MYH7B	c.5005G>A	p.Gly1669Ser	Missense	39/45	-
1-212799882-A-T	FAM71A	c.1663A>T	p.Lys555*	Nonsense	1/1	-
15-86801237-C-G	AGBL1	c.806C>G	p.Ser269Cys	Missense	8/25	-
13-32911391-CTA-TTT	BRCA2	c.2899_2901delCTAinsTTT	p.Leu967Phe	Missense	11/27	-
11-17470143-A-G	ABCC8	c.1252T>C	p.Cys418Arg	Missense	8/39	-
16-3023158-G-A	PKMYT1	c.1369C>T	p.Arg457Trp	Missense	8/9	-
22-46688704-C-A	TTC38	c.1333C>A	p.Arg445Ser	Missense	14/14	-
7-121758435-T-A	AASS	c.613A>T	p.Ile205Leu	Missense	6/24	-
7-121758435-T-C	AASS	c.613A>G	p.Ile205Val	Missense	6/24	-
17-37863291-C-T	ERBB2	c.122C>T	p.Thr41Ile	Missense	2/27	-
13-32890607-G-C	BRCA2	c.10G>C	p.Gly4Arg	Missense	2/27	-
13-32890607-G-A	BRCA2	c.10G>A	p.Gly4Arg	Missense	2/27	-
2-207557965-G-A	DYTN	c.914C>T	p.Ala305Val	Missense	9/12	-
17-74898683-C-G	MGAT5B	c.376C>G	p.Gln126Glu	Missense	4/17	-
9-418173-A-G	DOCK8	c.3806A>G	p.Asn1269Ser	Missense	30/48	-
2-207557965-G-T	DYTN	c.914C>A	p.Ala305Glu	Missense	9/12	-
12-77191233-A-G	ZDHHC17	c.113A>G	p.His38Arg	Missense	2/17	-
3-185209413-C-A	TMEM41A	c.707G>T	p.Gly236Val	Missense	5/5	-
17-61769706-G-A	MAP3K3	c.1579G>A	p.Val527Ile	Missense	15/16	-
1-95448643-G-A	ALG14	c.640C>T	p.Arg214*	Nonsense	4/4	-
3-121448088-G-T	GOLGB1	c.349C>A	p.Gln117Lys	Missense	4/22	-
3-185209413-C-T	TMEM41A	c.707G>A	p.Gly236Glu	Missense	5/5	-
7-92140266-T-C	PEX1	c.1579A>G	p.Thr527Ala	Missense	8/24	-
19-42342173-A-G	LYPD4	c.374T>C	p.Val125Ala	Missense	4/5	-
3-112648099-T-A	CD200R1	c.458A>T	p.Tyr153Phe	Missense	4/8	-
11-66392434-T-G	RBM14-RBM4	c.337+7906T>G	-	IntronicSNV	-	1/2
10-72489891-C-T	ADAMTS14	c.988C>T	p.Arg330Cys	Missense	6/22	-
16-23695377-A-C	PLK1	c.1003A>C	p.Ser335Arg	Missense	5/10	-
14-38064109-C-T	FOXA1	c.69G>A	p.Gln23Gln	Synonymous	1/2	-
1-22846721-G-A	ZBTB40	c.3001G>A	p.Val1001Ile	Missense	14/18	-
14-38064109-C-G	FOXA1	c.69G>C	p.Gln23His	Missense	1/2	-
4-72363294-A-C	SLC4A4	c.1919A>C	p.Asn640Thr	Missense	13/23	-
9-131267089-C-G	GLE1	c.5C>G	p.Pro2Arg	Missense	1/16	-
2-187702100-G-T	ZSWIM2	c.676C>A	p.Leu226Met	Missense	5/9	-
2-179528377-T-A	TTN	c.31484-595A>T	-	IntronicSNV	-	152/311
17-36091625-G-A	HNF1B	c.1006C>T	p.His336Tyr	Missense	4/9	-
2-179584437-C-G	TTN	c.20050G>C	p.Glu6684Gln	Missense	79/312	-
17-7579911-A-C	TP53	c.2T>G	p.Met1Arg	Missense	2/11	-
8-37689051-C-T	ADGRA2	c.1043C>T	p.Thr348Ile	Missense	8/19	-
21-43524191-G-A	UMODL1	c.1513G>A	p.Val505Met	Missense	9/23	-
17-7578181-G-A	TP53	c.668C>T	p.Pro223Leu	Missense	6/11	-
12-6952375-G-A	GNB3	c.241G>A	p.Val81Met	Missense	5/10	-
17-3101168-C-T	OR1A2	c.356C>T	p.Ala119Val	Missense	1/1	-
2-168110876-C-T	XIRP2	c.*240C>T	-	IntronicSNV	11/11	-
1-152281724-G-T	FLG	c.5638C>A	p.His1880Asn	Missense	3/3	-
12-80735883-G-T	OTOGL	c.5179G>T	p.Asp1727Tyr	Missense	43/58	-
9-125281999-C-T	OR1J4	c.580C>T	p.Leu194Phe	Missense	1/1	-
19-58005262-G-A	ZNF419	c.1337G>A	p.Arg446Gln	Missense	5/5	-
19-9578370-C-T	ZNF560	c.1253G>A	p.Gly418Asp	Missense	10/10	-
8-37796297-G-C	GOT1L1	c.218C>G	p.Thr73Ser	Missense	2/9	-
21-43524191-G-T	UMODL1	c.1513G>T	p.Val505Leu	Missense	9/23	-
13-32914305-G-T	BRCA2	c.5813G>T	p.Gly1938Val	Missense	11/27	-
1-152281724-G-C	FLG	c.5638C>G	p.His1880Asp	Missense	3/3	-
6-149997810-C-T	LATS1	c.2657G>A	p.Arg886Gln	Missense	6/8	-
16-20429546-C-G	ACSM5	c.370C>G	p.Arg124Gly	Missense	3/14	-
17-37676297-G-A	CDK12	c.3052G>A	p.Asp1018Asn	Missense	11/14	-
21-43524191-G-C	UMODL1	c.1513G>C	p.Val505Leu	Missense	9/23	-
17-74868836-A-G	MGAT5B	c.69-97A>G	-	IntronicSNV	-	1/16
7-48352767-T-C	ABCA13	c.9620T>C	p.Leu3207Pro	Missense	25/62	-
10-103827050-C-A	HPS6	c.1819C>A	p.Arg607Arg	Synonymous	1/1	-
11-65631998-C-T	MUS81	c.1090C>T	p.Arg364Trp	Missense	11/16	-
7-47342713-G-C	TNS3	c.3292C>G	p.Leu1098Val	Missense	22/31	-
10-103827050-C-T	HPS6	c.1819C>T	p.Arg607*	Nonsense	1/1	-
17-39135066-C-T	KRT40	c.1186G>A	p.Glu396Lys	Missense	8/9	-
17-39135066-C-A	KRT40	c.1186G>T	p.Glu396*	Nonsense	8/9	-
17-7579910-C-T	TP53	c.3G>A	p.Met1Ile	Missense	2/11	-
5-89918423-A-G	ADGRV1	c.463A>G	p.Ile155Val	Missense	5/90	-
3-69087870-C-A	TMF1	c.1996G>T	p.Glu666*	Nonsense	8/17	-
2-130878058-C-G	POTEF	c.31G>C	p.Ala11Pro	Missense	3/17	-
16-70296256-C-A	AARS	c.1664G>T	p.Ser555Ile	Missense	12/21	-
3-69087870-C-G	TMF1	c.1996G>C	p.Glu666Gln	Missense	8/17	-
19-9020771-G-A	MUC16	c.37331C>T	p.Ser12444Phe	Missense	20/84	-
10-3181157-G-A	PITRM1	c.2859C>T	p.Ile953Ile	Synonymous	25/27	-
19-9020771-G-T	MUC16	c.37331C>A	p.Ser12444Tyr	Missense	20/84	-
11-64108754-A-C	CCDC88B	c.401A>C	p.Glu134Ala	Missense	5/27	-
11-18387397-G-A	GTF2H1	c.1628G>A	p.Arg543His	Missense	15/15	-
5-118850709-G-A	HSD17B4	c.1471G>A	p.Ala491Thr	Missense	17/24	-
17-7579908-T-C	TP53	c.5A>G	p.Glu2Gly	Missense	2/11	-
13-32906539-T-G	BRCA2	c.924T>G	p.Phe308Leu	Missense	10/27	-
13-32906539-T-A	BRCA2	c.924T>A	p.Phe308Leu	Missense	10/27	-
13-32907140-A-T	BRCA2	c.1525A>T	p.Arg509*	Nonsense	10/27	-
20-40743945-A-G	PTPRT	c.2993T>C	p.Val998Ala	Missense	22/31	-
2-109421358-A-T	CCDC138	c.749A>T	p.Glu250Val	Missense	7/15	-
1-197073196-G-A	ASPM	c.5185C>T	p.Arg1729Trp	Missense	18/28	-
11-118918750-C-A	HYOU1	c.2419G>T	p.Gly807Trp	Missense	21/26	-
1-169701771-C-A	SELE	c.406G>T	p.Ala136Ser	Missense	3/14	-
1-208061255-T-C	CD34	c.*194A>G	-	3-UTRSNV	8/8	-
2-215657112-C-T	BARD1	c.273G>A	p.Trp91*	Nonsense	3/11	-
7-123119922-G-A	IQUB	c.1337C>T	p.Ala446Val	Missense	8/13	-
15-86076823-T-G	AKAP13	c.190T>G	p.Cys64Gly	Missense	4/37	-
16-2980747-C-T	FLYWCH1	c.659C>T	p.Pro220Leu	Missense	4/10	-
11-55563609-A-C	OR5D14	c.578A>C	p.Asp193Ala	Missense	1/1	-
17-18152710-C-T	FLII	c.1789G>A	p.Asp597Asn	Missense	15/30	-
19-17062930-G-T	CPAMD8	c.2498C>A	p.Ser833Tyr	Missense	20/42	-
13-32906995-T-G	BRCA2	c.1380T>G	p.Asn460Lys	Missense	10/27	-
7-117232223-C-A	CFTR	c.2002C>A	p.Arg668Ser	Missense	14/27	-
17-56679798-A-G	TEX14	c.1508T>C	p.Leu503Pro	Missense	12/33	-
8-17611381-C-G	MTUS1	c.1936G>C	p.Glu646Gln	Missense	2/15	-
16-2980747-C-G	FLYWCH1	c.659C>G	p.Pro220Arg	Missense	4/10	-
19-8206844-A-G	FBN3	c.719T>C	p.Ile240Thr	Missense	7/64	-
6-32084337-T-G	ATF6B	c.1793A>C	p.His598Pro	Missense	17/18	-
6-32084337-T-A	ATF6B	c.1793A>T	p.His598Leu	Missense	17/18	-
14-68250147-C-T	ZFYVE26	c.3722G>A	p.Arg1241Gln	Missense	21/42	-
11-55563609-A-G	OR5D14	c.578A>G	p.Asp193Gly	Missense	1/1	-
3-39142562-G-T	GORASP1	c.380C>A	p.Ala127Asp	Missense	4/9	-
1-45798269-T-C	MUTYH	c.658A>G	p.Ile220Val	Missense	8/16	-
1-24192103-C-G	FUCA1	c.402G>C	p.Leu134Phe	Missense	2/8	-
12-49373410-T-A	WNT1	c.264T>A	p.Ser88Arg	Missense	2/4	-
2-242066103-G-A	PASK	c.2227C>T	p.Leu743Phe	Missense	10/18	-
3-69987012-C-A	MITF	c.394C>A	p.Gln132Lys	Missense	3/10	-
7-128441249-G-A	CCDC136	c.356G>A	p.Arg119His	Missense	4/18	-
10-27687437-C-A	PTCHD3	c.2090G>T	p.Trp697Leu	Missense	4/4	-
19-11332560-G-T	DOCK6	c.3517C>A	p.Arg1173Arg	Synonymous	28/48	-
17-36091625-G-T	HNF1B	c.1006C>A	p.His336Asn	Missense	4/9	-
17-36091625-G-C	HNF1B	c.1006C>G	p.His336Asp	Missense	4/9	-
4-1980565-C-T	NSD2	c.4027C>T	p.Pro1343Ser	Missense	24/24	-
4-1980565-C-A	NSD2	c.4027C>A	p.Pro1343Thr	Missense	24/24	-
4-1980565-C-G	NSD2	c.4027C>G	p.Pro1343Ala	Missense	24/24	-
5-70900270-T-A	MCCC2	c.599T>A	p.Ile200Asn	Missense	6/17	-
22-45132831-G-A	PRR5	c.844G>A	p.Glu282Lys	Missense	9/9	-
10-101610499-A-C	ABCC2	c.4454A>C	p.His1485Pro	Missense	31/32	-
11-418414-G-C	ANO9	c.2306C>G	p.Pro769Arg	Missense	23/23	-
11-418414-G-A	ANO9	c.2306C>T	p.Pro769Leu	Missense	23/23	-
19-11332560-G-A	DOCK6	c.3517C>T	p.Arg1173Trp	Missense	28/48	-
9-80943928-A-C	PSAT1	c.901A>C	p.Asn301His	Missense	8/8	-
6-33283570-A-T	ZBTB22	c.1124T>A	p.Val375Asp	Missense	2/2	-
19-39996089-A-G	DLL3	c.1091A>G	p.Asn364Ser	Missense	6/8	-
10-126686605-C-T	CTBP2	c.493G>A	p.Val165Met	Missense	6/11	-
17-7578550-GA-CT	TP53	c.379_380delTCinsCT	p.Ser127Leu	Missense	5/11	-
5-145551522-T-C	LARS	c.245A>G	p.Lys82Arg	Missense	4/32	-
15-44856862-G-A	SPG11	c.6695C>T	p.Pro2232Leu	Missense	37/38	-
11-64037602-G-C	BAD	c.*79C>G	-	3-UTRSNV	4/4	-
11-64037602-G-A	BAD	c.*79C>T	-	3-UTRSNV	4/4	-
19-2408436-G-A	TMPRSS9	c.823G>A	p.Val275Met	Missense	7/17	-
13-32906966-TAG-T	BRCA2	c.1351_1352delAG	p.Ser451Profs*10	Frameshift	10/27	-
3-15259048-A-G	CAPN7	c.328A>G	p.Ile110Val	Missense	3/21	-
7-121682694-T-C	PTPRZ1	c.5834T>C	p.Val1945Ala	Missense	22/30	-
17-48559521-G-A	RSAD1	c.544G>A	p.Ala182Thr	Missense	4/9	-
14-64687258-A-T	SYNE2	c.19964A>T	p.Gln6655Leu	Missense	111/116	-
2-202957848-T-C	KIAA2012	c.625T>C	p.Tyr209His	Missense	4/24	-
2-203991333-T-G	NBEAL1	c.2952T>G	p.Ile984Met	Missense	21/55	-
3-137822704-C-T	DZIP1L	c.110G>A	p.Arg37His	Missense	2/16	-
3-133368472-T-C	TOPBP1	c.1259A>G	p.His420Arg	Missense	10/28	-
3-184603910-G-A	VPS8	c.1741G>A	p.Val581Ile	Missense	21/47	-
7-103205779-G-A	RELN	c.5156C>T	p.Ser1719Leu	Missense	34/65	-
17-56694937-T-A	TEX14	c.598A>T	p.Ile200Phe	Missense	6/33	-
2-74643215-C-T	C2orf81	c.181G>A	p.Asp61Asn	Missense	2/4	-
7-105660850-A-G	CDHR3	c.1685A>G	p.Glu562Gly	Missense	13/19	-
2-179452501-T-C	TTN	c.55831A>G	p.Ser18611Gly	Missense	255/312	-
14-45605405-G-A	FANCM	c.171G>A	p.Leu57Leu	Synonymous	1/23	-
14-45605405-G-C	FANCM	c.171G>C	p.Leu57Phe	Missense	1/23	-
1-201356205-C-T	LAD1	c.284G>A	p.Arg95Gln	Missense	3/10	-
19-2799757-C-T	THOP1	c.557C>T	p.Thr186Met	Missense	5/13	-
13-103701690-G-T	SLC10A2	c.868C>A	p.Pro290Thr	Missense	5/6	-
8-23167422-C-T	LOXL2	c.1639G>A	p.Ala547Thr	Missense	10/14	-
19-2424194-C-T	TMPRSS9	c.2554C>T	p.Arg852Cys	Missense	14/17	-
7-100176362-C-T	LRCH4	c.646G>A	p.Val216Ile	Missense	5/18	-
15-90984854-T-G	IQGAP1	c.766T>G	p.Ser256Ala	Missense	8/38	-
1-243589830-A-G	SDCCAG8	c.1955A>G	p.His652Arg	Missense	16/18	-
17-7579556-A-G	TP53	c.131T>C	p.Met44Thr	Missense	4/11	-
5-79024949-G-C	CMYA5	c.361G>C	p.Val121Leu	Missense	2/13	-
17-7637938-A-G	DNAH2	c.890A>G	p.Lys297Arg	Missense	7/86	-
1-17668888-A-G	PADI4	c.926A>G	p.Tyr309Cys	Missense	8/16	-
17-10404653-C-G	MYH1	c.3512G>C	p.Arg1171Pro	Missense	27/40	-
5-26885797-T-C	CDH9	c.1808A>G	p.Glu603Gly	Missense	11/12	-
9-130116658-C-T	GARNL3	c.1728C>T	p.Asp576Asp	Synonymous	19/28	-
4-108969836-C-T	LEF1	c.*78G>A	-	3_prime_UTR_variant	11/11	-
3-98001858-A-G	OR5H2	c.127A>G	p.Thr43Ala	Missense	1/1	-
9-130116658-C-G	GARNL3	c.1728C>G	p.Asp576Glu	Missense	19/28	-
2-136107663-T-C	ZRANB3	c.482A>G	p.Tyr161Cys	Missense	5/21	-
3-39142562-G-A	GORASP1	c.380C>T	p.Ala127Val	Missense	4/9	-
3-39142562-G-C	GORASP1	c.380C>G	p.Ala127Gly	Missense	4/9	-
11-802020-C-T	PIDD1	c.1247G>A	p.Arg416Gln	Missense	7/16	-
10-126686605-C-A	CTBP2	c.493G>T	p.Val165Leu	Missense	6/11	-
14-64408645-A-G	SYNE2	c.280A>G	p.Ile94Val	Missense	5/116	-
12-113596869-C-T	CFAP73	c.*375C>T	-	3_prime_UTR_variant	8/8	-
1-208072436-G-T	CD34	c.398C>A	p.Thr133Asn	Missense	3/8	-
6-32008500-G-C	CYP21A2	c.1174G>C	p.Ala392Pro	Missense	9/10	-
12-2797746-G-A	CACNA1C	c.5918G>A	p.Arg1973Gln	Missense	46/47	-
16-89865598-G-A	FANCA	c.869C>T	p.Ser290Phe	Missense	10/43	-
17-37864713-C-G	ERBB2	c.365C>G	p.Pro122Arg	Missense	3/27	-
19-49691898-G-A	TRPM4	c.1744G>A	p.Gly582Ser	Missense	13/25	-
1-152190873-G-T	HRNR	c.3232C>A	p.Gln1078Lys	Missense	3/3	-
2-190606152-A-G	ANKAR	c.3785A>G	p.Tyr1262Cys	Missense	20/23	-
14-66975271-C-G	GPHN	c.26C>G	p.Thr9Ser	Missense	1/23	-
1-208072436-G-C	CD34	c.398C>G	p.Thr133Ser	Missense	3/8	-
1-208072436-G-A	CD34	c.398C>T	p.Thr133Ile	Missense	3/8	-
3-53769508-G-A	CACNA1D	c.2789G>A	p.Arg930His	Missense	21/49	-
6-32008500-G-A	CYP21A2	c.1174G>A	p.Ala392Thr	Missense	9/10	-
17-37879573-C-A	ERBB2	c.1948C>A	p.Pro650Thr	Missense	17/27	-
2-120020831-C-T	STEAP3	c.1384C>T	p.Arg462Trp	Missense	6/6	-
13-32911202-G-C	BRCA2	c.2710G>C	p.Gly904Arg	Missense	11/27	-
13-32911202-G-A	BRCA2	c.2710G>A	p.Gly904Arg	Missense	11/27	-
16-89865598-G-C	FANCA	c.869C>G	p.Ser290Cys	Missense	10/43	-
16-89865598-G-T	FANCA	c.869C>A	p.Ser290Tyr	Missense	10/43	-
17-7577093-CG-TA	TP53	c.844_845delCGinsTA	p.Arg282*	Nonsense	8/11	-
2-190606152-A-C	ANKAR	c.3785A>C	p.Tyr1262Ser	Missense	20/23	-
17-45214600-A-G	CDC27	c.1849T>C	p.Phe617Leu	Missense	14/19	-
16-2983209-G-A	FLYWCH1	c.872G>A	p.Arg291Gln	Missense	5/10	-
16-2983209-G-C	FLYWCH1	c.872G>C	p.Arg291Pro	Missense	5/10	-
X-19433335-G-A	MAP3K15	c.1480C>T	p.Arg494Cys	Missense	10/29	-
11-47663996-C-T	MTCH2	c.22G>A	p.Val8Met	Missense	1/13	-
X-19433335-G-T	MAP3K15	c.1480C>A	p.Arg494Ser	Missense	10/29	-
2-198948717-A-G	PLCL1	c.476A>G	p.Asp159Gly	Missense	2/6	-
17-10404653-C-T	MYH1	c.3512G>A	p.Arg1171Gln	Missense	27/40	-
X-1557993-G-C	ASMTL	c.270C>G	p.Ile90Met	Missense	3/13	-
17-71196139-C-T	COG1	c.1049C>T	p.Thr350Met	Missense	5/14	-
17-37864748-C-A	ERBB2	c.400C>A	p.Pro134Thr	Missense	3/27	-
1-55559716-C-T	USP24	c.6248G>A	p.Arg2083Gln	Missense	52/68	-
6-161022107-C-T	LPA	c.2969G>A	p.Arg990Gln	Missense	19/39	-
6-161022107-C-A	LPA	c.2969G>T	p.Arg990Leu	Missense	19/39	-
17-10401968-G-A	MYH1	c.4156C>T	p.Arg1386Cys	Missense	30/40	-
4-187078745-A-G	FAM149A	c.601A>G	p.Lys201Glu	Missense	8/14	-
15-65703439-C-A	IGDCC4	c.340G>T	p.Val114Phe	Missense	2/20	-
17-77705076-C-T	ENPP7	c.175C>T	p.Arg59*	Nonsense	1/6	-
17-76554204-C-T	DNAH17	c.2164G>A	p.Gly722Ser	Missense	14/81	-
19-55263830-A-T	KIR2DL3	c.885A>T	p.Glu295Asp	Missense	8/8	-
13-32913666-C-G	BRCA2	c.5174C>G	p.Ala1725Gly	Missense	11/27	-
1-223178133-C-A	DISP1	c.3394C>A	p.Arg1132Arg	Synonymous	10/10	-
1-223178133-C-T	DISP1	c.3394C>T	p.Arg1132Trp	Missense	10/10	-
2-105859066-C-T	GPR45	c.751C>T	p.Arg251Trp	Missense	1/1	-
2-105859066-C-G	GPR45	c.751C>G	p.Arg251Gly	Missense	1/1	-
17-76554204-C-G	DNAH17	c.2164G>C	p.Gly722Arg	Missense	14/81	-
13-32893264-C-T	BRCA2	c.118C>T	p.Pro40Ser	Missense	3/27	-
X-50438789-C-T	SHROOM4	c.266G>A	p.Arg89Lys	Missense	2/9	-
21-43557725-G-A	UMODL1	c.3952G>A	p.Glu1318Lys	Missense	22/23	-
20-62293880-C-T	RTEL1	c.449C>T	p.Thr150Met	Missense	5/35	-
3-127327309-G-A	MCM2	c.1186G>A	p.Ala396Thr	Missense	7/16	-
1-233136167-C-T	PCNX2	c.5212G>A	p.Ala1738Thr	Missense	30/34	-
4-126238305-C-A	FAT4	c.739C>A	p.Pro247Thr	Missense	1/17	-
4-126238305-C-T	FAT4	c.739C>T	p.Pro247Ser	Missense	1/17	-
10-91177152-C-G	IFIT5	c.196C>G	p.Gln66Glu	Missense	2/2	-
5-118850709-G-T	HSD17B4	c.1471G>T	p.Ala491Ser	Missense	17/24	-
19-8320554-C-T	CERS4	c.355C>T	p.Arg119Trp	Missense	5/12	-
9-140637904-A-G	EHMT1	c.905A>G	p.Lys302Arg	Missense	5/27	-
7-151078993-C-T	WDR86	c.937G>A	p.Gly313Ser	Missense	5/6	-
13-32893406-CT-TG	BRCA2	c.260_261delCTinsTG	p.Thr87Met	Missense	3/27	-
19-49685865-G-T	TRPM4	c.1294G>T	p.Ala432Ser	Missense	11/25	-
20-43653713-C-T	STK4	c.1247C>T	p.Pro416Leu	Missense	10/11	-
20-46264116-G-T	NCOA3	c.1163G>T	p.Arg388Ile	Missense	11/23	-
17-37882905-T-C	ERBB2	c.2963T>C	p.Val988Ala	Missense	24/27	-
14-24587680-G-C	DCAF11	c.661G>C	p.Val221Leu	Missense	7/15	-
11-56258341-C-A	OR5M8	c.506G>T	p.Gly169Val	Missense	1/1	-
11-432044-G-A	ANO9	c.361C>T	p.Arg121*	Nonsense	5/23	-
2-85571211-G-T	RETSAT	c.1444C>A	p.Arg482Arg	Synonymous	9/11	-
17-45214592-T-G	CDC27	c.1857A>C	p.Leu619Phe	Missense	14/19	-
3-133368472-T-G	TOPBP1	c.1259A>C	p.His420Pro	Missense	10/28	-
1-235884023-G-C	LYST	c.9498C>G	p.Phe3166Leu	Missense	40/53	-
2-85571211-G-A	RETSAT	c.1444C>T	p.Arg482Trp	Missense	9/11	-
11-105880425-T-A	MSANTD4	c.875A>T	p.Asp292Val	Missense	3/3	-
4-48683105-G-A	FRYL	c.-81+3585C>T	-	intron_variant	-	3/63
7-48278988-C-T	ABCA13	c.1048C>T	p.Arg350*	Nonsense	9/62	-
7-103767338-G-A	ORC5	c.1265C>T	p.Thr422Met	Missense	14/14	-
20-44048782-C-T	PIGT	c.688C>T	p.Arg230Cys	Missense	6/12	-
5-11732304-C-T	CTNND2	c.118G>A	p.Gly40Arg	Missense	2/22	-
7-48278988-C-G	ABCA13	c.1048C>G	p.Arg350Gly	Missense	9/62	-
7-6013060-G-C	PMS2	c.2559C>G	p.Ile853Met	Missense	15/15	-
4-8620201-C-A	CPZ	c.1516C>A	p.Pro506Thr	Missense	9/10	-
6-46659721-G-T	TDRD6	c.3856G>T	p.Asp1286Tyr	Missense	1/4	-
7-100683213-C-T	MUC17	c.8516C>T	p.Thr2839Ile	Missense	3/13	-
20-44639599-C-G	MMP9	c.559C>G	p.Leu187Val	Missense	4/13	-
2-162851539-C-T	DPP4	c.2131G>A	p.Val711Ile	Missense	25/26	-
9-131397116-C-T	WDR34	c.1066G>A	p.Gly356Ser	Missense	7/9	-
19-49898459-A-G	CCDC155	c.245A>G	p.Asp82Gly	Missense	4/20	-
7-149422444-G-A	KRBA1	c.1165G>A	p.Ala389Thr	Missense	10/18	-
17-37868193-C-G	ERBB2	c.914C>G	p.Ser305Cys	Missense	8/27	-
6-31727989-A-G	MSH5	c.1808A>G	p.Lys603Arg	Missense	19/25	-
16-75276702-G-A	BCAR1	c.299C>T	p.Thr100Met	Missense	2/7	-
7-100647976-C-G	MUC12	c.14132C>G	p.Ser4711Cys	Missense	2/12	-
X-132351308-G-A	TFDP3	c.980C>T	p.Pro327Leu	Missense	1/1	-
1-95538342-C-A	ALG14	c.113G>T	p.Ser38Ile	Missense	1/4	-
3-185214748-G-T	TMEM41A	c.141C>A	p.Asp47Glu	Missense	2/5	-
21-43543057-C-A	UMODL1	c.2944C>A	p.Arg982Arg	Synonymous	17/23	-
1-152329370-A-G	FLG2	c.892T>C	p.Cys298Arg	Missense	3/3	-
3-13916570-C-T	WNT7A	c.172G>A	p.Ala58Thr	Missense	2/4	-
1-20669689-G-A	VWA5B1	c.2429G>A	p.Gly810Asp	Missense	16/22	-
22-42910722-G-T	RRP7A	c.524C>A	p.Thr175Lys	Missense	5/7	-
17-10401968-G-T	MYH1	c.4156C>A	p.Arg1386Ser	Missense	30/40	-
19-49339623-C-T	HSD17B14	c.46G>A	p.Gly16Arg	Missense	1/9	-
3-137822704-C-A	DZIP1L	c.110G>T	p.Arg37Leu	Missense	2/16	-
19-4525845-C-G	PLIN5	c.521-1G>C	-	IntronicSNV	-	5/7
6-109274354-C-T	ARMC2	c.1715C>T	p.Thr572Met	Missense	13/18	-
17-71196139-C-G	COG1	c.1049C>G	p.Thr350Arg	Missense	5/14	-
21-43543057-C-T	UMODL1	c.2944C>T	p.Arg982Trp	Missense	17/23	-
15-99451976-G-A	IGF1R	c.1310G>A	p.Arg437His	Missense	6/21	-
20-60892518-C-T	LAMA5	c.7394G>A	p.Arg2465Gln	Missense	55/80	-
17-79514982-G-C	FAAP100	c.1404-278C>G	-	IntronicSNV	-	4/8
2-116066887-G-C	DPP10	c.133G>C	p.Val45Leu	Missense	2/26	-
12-102158956-T-C	GNPTAB	c.1739A>G	p.Tyr580Cys	Missense	13/21	-
X-129147028-G-A	BCORL1	c.280G>A	p.Asp94Asn	Missense	3/12	-
19-49339623-C-A	HSD17B14	c.46G>T	p.Gly16Trp	Missense	1/9	-
3-15478047-G-A	EAF1	c.725G>A	p.Arg242Gln	Missense	5/6	-
15-78893644-C-T	CHRNA3	c.1340G>A	p.Ser447Asn	Missense	5/6	-
3-108189571-C-T	MYH15	c.1417G>A	p.Asp473Asn	Missense	14/42	-
9-117103859-C-T	AKNA	c.4021G>A	p.Ala1341Thr	Missense	21/22	-
8-17823611-G-A	PCM1	c.2959G>A	p.Val987Met	Missense	19/39	-
13-32907326-TT-T	BRCA2	c.1711delT	p.Ser571Leufs*2	Frameshift	10/27	-
6-20490428-G-T	E2F3	c.772G>T	p.Asp258Tyr	Missense	7/7	-
7-151945051-A-T	KMT2C	c.2468T>A	p.Ile823Asn	Missense	14/59	-
7-151945051-A-G	KMT2C	c.2468T>C	p.Ile823Thr	Missense	14/59	-
2-43010497-C-G	HAAO	c.307G>C	p.Val103Leu	Missense	4/10	-
12-11285924-C-G	TAS2R30	c.920G>C	p.Arg307Pro	Missense	1/1	-
12-18891703-C-A	CAPZA3	c.501C>A	p.Asn167Lys	Missense	1/1	-
2-27353418-G-A	ABHD1	c.1024G>A	p.Ala342Thr	Missense	9/9	-
X-140993320-A-G	MAGEC1	c.130A>G	p.Ser44Gly	Missense	4/4	-
X-47041224-C-T	RBM10	c.1652C>T	p.Pro551Leu	Missense	15/24	-
17-7576876-C-T	TP53	c.970G>A	p.Asp324Asn	Missense	9/11	-
11-7663588-G-A	PPFIBP2	c.1577G>A	p.Arg526Gln	Missense	17/24	-
12-117724018-T-G	NOS1	c.1181A>C	p.Asp394Ala	Missense	6/29	-
17-7578228-A-T	TP53	c.621T>A	p.Asp207Glu	Missense	6/11	-
17-7578228-A-C	TP53	c.621T>G	p.Asp207Glu	Missense	6/11	-
20-30729619-G-C	TM9SF4	c.449G>C	p.Arg150Pro	Missense	5/18	-
X-1554587-C-T	ASMTL	c.338G>A	p.Arg113Gln	Missense	4/13	-
13-32900646-CA-TG	BRCA2	c.527_528delCAinsTG	p.Thr176Met	Missense	7/27	-
11-43465025-G-A	TTC17	c.2402G>A	p.Arg801His	Missense	17/24	-
11-47663986-C-T	MTCH2	c.32G>A	p.Gly11Asp	Missense	1/13	-
2-240913012-G-C	NDUFA10	c.1000-12409C>G	-	IntronicSNV	-	9/9
13-32911284-GA-AC	BRCA2	c.2792_2793delGAinsAC	p.Gly931Asp	Missense	11/27	-
1-15893664-C-T	DNAJC16	c.1849C>T	p.Arg617Cys	Missense	14/15	-
19-42931022-C-T	LIPE	c.280G>A	p.Ala94Thr	Missense	1/10	-
X-1557993-G-A	ASMTL	c.270C>T	p.Ile90Ile	Synonymous	3/13	-
12-111291255-C-G	CCDC63	c.56C>G	p.Ser19Trp	Missense	3/12	-
1-36225997-G-A	CLSPN	c.1525C>T	p.Arg509Trp	Missense	8/25	-
X-57515249-G-C	FAAH2	c.1483G>C	p.Gly495Arg	Missense	11/11	-
1-36225997-G-T	CLSPN	c.1525C>A	p.Arg509Arg	Synonymous	8/25	-
11-55761605-A-G	OR5F1	c.497T>C	p.Leu166Ser	Missense	1/1	-
X-17750294-T-A	NHS	c.4603T>A	p.Ser1535Thr	Missense	8/8	-
7-6013060-G-A	PMS2	c.2559C>T	p.Ile853Ile	Synonymous	15/15	-
2-186653566-A-T	FSIP2	c.1703A>T	-	missense_variant	16/23	-
2-186653566-A-G	FSIP2	c.1703A>G	-	missense_variant	16/23	-
4-170189999-C-T	SH3RF1	c.365G>A	p.Arg122Gln	Missense	2/12	-
2-179441295-T-C	TTN	c.61972A>G	p.Ser20658Gly	Missense	274/312	-
19-50393043-C-T	IL4I1	c.1654G>A	p.Val552Met	Missense	10/10	-
1-167384979-T-C	POU2F1	c.2233T>C	p.Ser745Pro	Missense	16/16	-
19-49967718-A-T	ALDH16A1	c.1376A>T	p.Asp459Val	Missense	11/17	-
1-197111665-G-A	ASPM	c.1717C>T	p.Arg573Trp	Missense	3/28	-
12-57858576-C-A	GLI1	c.314C>A	p.Ser105Tyr	Missense	4/12	-
4-170189999-C-G	SH3RF1	c.365G>C	p.Arg122Pro	Missense	2/12	-
7-117232223-C-T	CFTR	c.2002C>T	p.Arg668Cys	Missense	14/27	-
17-10401968-G-C	MYH1	c.4156C>G	p.Arg1386Gly	Missense	30/40	-
15-42145593-C-T	SPTBN5	c.10033G>A	p.Asp3345Asn	Missense	59/68	-
9-131267089-C-A	GLE1	c.5C>A	p.Pro2Gln	Missense	1/16	-
9-124081138-G-A	GSN	c.1324G>A	p.Asp442Asn	Missense	9/17	-
1-156933011-G-A	ARHGEF11	c.1124C>T	p.Ala375Val	Missense	13/41	-
1-65851423-G-C	DNAJC6	c.829G>C	p.Ala277Pro	Missense	7/19	-
1-65851423-G-A	DNAJC6	c.829G>A	p.Ala277Thr	Missense	7/19	-
13-32900238-T-TA	BRCA2	c.426_427insA	-	SpliceAcceptorInsertion	5/27	-
17-7579324-AG-AA	TP53	c.362_363delCTinsAA	p.Ser121*	Nonsense	4/11	-
19-12429782-G-C	ZNF563	c.1057C>G	p.Arg353Gly	Missense	4/4	-
19-12429782-G-A	ZNF563	c.1057C>T	p.Arg353*	Nonsense	4/4	-
22-39715102-T-G	RPL3	c.3+498A>C	-	IntronicSNV	-	1/9
22-39715102-T-C	RPL3	c.3+498A>G	-	IntronicSNV	-	1/9
22-39715102-T-A	RPL3	c.3+498A>T	-	IntronicSNV	-	1/9
20-60901932-C-T	LAMA5	c.5203G>A	p.Val1735Met	Missense	39/80	-
1-20639370-G-A	VWA5B1	c.181G>A	p.Gly61Ser	Missense	3/22	-
1-1277534-G-A	DVL1	c.365C>T	p.Pro122Leu	Missense	4/15	-
1-1277534-G-C	DVL1	c.365C>G	p.Pro122Arg	Missense	4/15	-
4-79328847-C-T	FRAS1	c.4160C>T	p.Ala1387Val	Missense	31/42	-
13-32893276-TC-GG	BRCA2	c.130_131delTCinsGG	p.Ser44Gly	Missense	3/27	-
10-101610499-A-G	ABCC2	c.4454A>G	p.His1485Arg	Missense	31/32	-
14-105353811-C-T	CEP170B	c.3235C>T	p.Arg1079Cys	Missense	12/19	-
17-37865688-C-T	ERBB2	c.557C>T	p.Thr186Ile	Missense	4/27	-
20-10622214-C-A	JAG1	c.2810G>T	p.Arg937Leu	Missense	23/26	-
10-102089635-C-A	PKD2L1	c.226G>T	p.Gly76Cys	Missense	1/16	-
11-14913631-G-T	CYP2R1	c.121C>A	p.Pro41Thr	Missense	1/5	-
1-120468201-A-T	NOTCH2	c.4238T>A	p.Leu1413His	Missense	25/34	-
20-57768809-C-T	ZNF831	c.2735C>T	p.Ala912Val	Missense	1/5	-
11-47359334-C-G	MYBPC3	c.2320G>C	p.Ala774Pro	Missense	24/35	-
11-47359334-C-T	MYBPC3	c.2320G>A	p.Ala774Thr	Missense	24/35	-
12-18891466-C-G	CAPZA3	c.264C>G	p.Ser88Arg	Missense	1/1	-
20-10622214-C-T	JAG1	c.2810G>A	p.Arg937Gln	Missense	23/26	-
7-2297115-T-C	SNX8	c.1019A>G	p.His340Arg	Missense	9/11	-
13-32367033-C-T	RXFP2	c.1594C>T	p.Arg532*	Nonsense	16/18	-
17-7574019-C-A	TP53	c.1008G>T	p.Glu336Asp	Missense	10/11	-
11-14913631-G-C	CYP2R1	c.121C>G	p.Pro41Ala	Missense	1/5	-
22-23915761-C-A	IGLL1	c.334G>T	p.Ala112Ser	Missense	3/3	-
2-46603764-T-A	EPAS1	c.1121T>A	p.Phe374Tyr	Missense	9/16	-
14-105415031-C-A	AHNAK2	c.6757G>T	p.Gly2253Cys	Missense	7/7	-
13-41134399-G-C	FOXO1	c.1229C>G	p.Pro410Arg	Missense	2/3	-
9-136029406-T-C	GBGT1	c.602A>G	p.Tyr201Cys	Missense	7/7	-
19-38875072-G-A	GGN	c.1939C>T	p.Gln647*	Nonsense	4/4	-
1-34330137-C-A	CSMD2	c.801-17540G>T	-	IntronicSNV	-	5/69
19-38875072-G-C	GGN	c.1939C>G	p.Gln647Glu	Missense	4/4	-
16-4935694-C-T	PPL	c.2962G>A	p.Gly988Arg	Missense	22/22	-
3-120394672-A-T	HGD	c.54T>A	p.Asp18Glu	Missense	2/14	-
3-184648315-G-A	VPS8	c.2851G>A	p.Glu951Lys	Missense	33/47	-
17-47246211-C-T	B4GALNT2	c.1444C>T	p.Arg482*	Nonsense	10/11	-
19-50918229-G-A	POLD1	c.2546G>A	p.Arg849His	Missense	20/27	-
9-79985363-G-A	VPS13A	c.8776G>A	p.Gly2926Ser	Missense	65/69	-
19-40580431-C-G	ZNF780A	c.1918G>C	p.Ala640Pro	Missense	6/6	-
6-10874905-A-C	GCM2	c.844T>G	p.Tyr282Asp	Missense	5/5	-
11-62298022-C-G	AHNAK	c.342+4453G>C	-	IntronicSNV	-	4/5
17-7578465-G-A	TP53	c.465C>T	p.Thr155Thr	Synonymous	5/11	-
16-4935694-C-G	PPL	c.2962G>C	p.Gly988Arg	Missense	22/22	-
9-131467682-G-A	PKN3	c.125G>A	p.Arg42His	Missense	2/22	-
13-32907524-AGGTACCTCTGTCTTTTTTTTTTTGTAAATAGTACATATAGTTTTATAGATGACGATTCC-A	BRCA2	c.1909_1910del2879	-	Multi:SpliceDonorDeletion,SpliceAcceptorDeletion	10/27	10/26
11-6891726-C-A	OR10A2	c.741C>A	p.Phe247Leu	Missense	1/1	-
17-7578465-G-T	TP53	c.465C>A	p.Thr155Thr	Synonymous	5/11	-
19-42841018-C-T	MEGF8	c.1304C>T	p.Thr435Met	Missense	7/41	-
12-21229413-G-A	SLCO1B7	c.1634G>A	p.Gly545Glu	Missense	12/13	-
2-233164774-C-T	DIS3L2	c.1684C>T	p.His562Tyr	Missense	14/21	-
14-51288636-G-C	NIN	c.139C>G	p.Pro47Ala	Missense	3/30	-
13-32907480-C-T	BRCA2	c.1865C>T	p.Ala622Val	Missense	10/27	-
11-1078456-C-T	MUC2	c.664C>T	p.Arg222Cys	Missense	6/51	-
13-77739411-A-T	MYCBP2	c.6456T>A	p.Asp2152Glu	Missense	42/83	-
15-62219337-G-A	VPS13C	c.6340C>T	p.Leu2114Phe	Missense	50/83	-
6-147635108-C-G	STXBP5	c.1234C>G	p.Leu412Val	Missense	12/28	-
2-179476308-G-A	TTN	c.42944C>T	p.Pro14315Leu	Missense	218/312	-
2-97755924-C-A	FAHD2B	c.384G>T	p.Lys128Asn	Missense	3/8	-
2-179476308-G-T	TTN	c.42944C>A	p.Pro14315His	Missense	218/312	-
10-134621945-C-T	CFAP46	c.8128G>A	p.Val2710Met	Missense	58/58	-
10-134621945-C-G	CFAP46	c.8128G>C	p.Val2710Leu	Missense	58/58	-
X-55039952-G-T	ALAS2	c.1567C>A	p.His523Asn	Missense	10/11	-
6-161007619-G-A	LPA	c.3991C>T	p.Arg1331Cys	Missense	25/39	-
6-161007619-G-T	LPA	c.3991C>A	p.Arg1331Ser	Missense	25/39	-
X-55039952-G-C	ALAS2	c.1567C>G	p.His523Asp	Missense	10/11	-
X-55039952-G-A	ALAS2	c.1567C>T	p.His523Tyr	Missense	10/11	-
3-50112609-G-C	RBM6	c.3117-25G>C	-	IntronicSNV	-	19/20
13-32907180-GGT-G	BRCA2	c.1565_1566delGT	p.Gly522Alafs*4	Frameshift	10/27	-
17-7684442-A-T	DNAH2	c.6086A>T	p.Asp2029Val	Missense	39/86	-
19-11034281-C-T	YIPF2	c.724G>A	p.Gly242Arg	Missense	8/10	-
19-11034281-C-G	YIPF2	c.724G>C	p.Gly242Arg	Missense	8/10	-
17-7579347-AAGAA-A	TP53	c.338_341delTCTT	p.Phe113Cysfs*9	Frameshift	4/11	-
20-60892011-C-T	LAMA5	c.7580G>A	p.Arg2527His	Missense	56/80	-
19-9056616-G-A	MUC16	c.30830C>T	p.Thr10277Ile	Missense	3/84	-
9-5770093-A-G	RIC1	c.3431A>G	p.Glu1144Gly	Missense	23/26	-
9-5770093-A-T	RIC1	c.3431A>T	p.Glu1144Val	Missense	23/26	-
17-7684442-A-C	DNAH2	c.6086A>C	p.Asp2029Ala	Missense	39/86	-
17-7684442-A-G	DNAH2	c.6086A>G	p.Asp2029Gly	Missense	39/86	-
1-218520315-G-A	TGFB2	c.272G>A	p.Arg91His	Missense	1/7	-
17-18154791-C-G	FLII	c.1384G>C	p.Glu462Gln	Missense	13/30	-
8-95404072-A-C	RAD54B	c.1574T>G	p.Leu525Arg	Missense	10/15	-
13-23914588-G-A	SACS	c.3427C>T	p.Gln1143*	Nonsense	10/10	-
5-167653121-G-A	TENM2	c.5110G>A	p.Val1704Met	Missense	25/30	-
17-37866390-C-T	ERBB2	c.695C>T	p.Pro232Leu	Missense	6/27	-
20-60892011-C-A	LAMA5	c.7580G>T	p.Arg2527Leu	Missense	56/80	-
14-102507911-C-G	DYNC1H1	c.11942C>G	p.Thr3981Arg	Missense	65/78	-
12-53555083-G-A	CSAD	c.874C>T	p.Arg292Cys	Missense	11/17	-
4-1729887-G-T	TACC3	c.758G>T	p.Gly253Val	Missense	4/16	-
16-20439162-G-T	ACSM5	c.974G>T	p.Arg325Leu	Missense	7/14	-
16-20439162-G-A	ACSM5	c.974G>A	p.Arg325Gln	Missense	7/14	-
1-204971736-A-G	NFASC	c.3149A>G	p.Lys1050Arg	Missense	27/30	-
15-77406854-G-C	PEAK1	c.4885C>G	p.Pro1629Ala	Missense	8/8	-
17-43215099-G-A	ACBD4	c.503-28G>A	-	IntronicSNV	-	5/8
19-55481394-C-A	NLRP2	c.11C>A	p.Ser4*	Nonsense	2/13	-
19-55481394-C-T	NLRP2	c.11C>T	p.Ser4Leu	Missense	2/13	-
1-53352682-G-C	ZYG11A	c.2061G>C	p.Gln687His	Missense	13/14	-
2-125660581-G-A	CNTNAP5	c.3556G>A	p.Ala1186Thr	Missense	22/24	-
1-110882077-G-C	RBM15	c.50G>C	p.Arg17Pro	Missense	1/3	-
15-28473387-G-A	HERC2	c.5441C>T	p.Thr1814Met	Missense	35/93	-
7-105656471-G-T	CDHR3	c.1426G>T	p.Ala476Ser	Missense	11/19	-
7-105656471-G-A	CDHR3	c.1426G>A	p.Ala476Thr	Missense	11/19	-
7-55914251-C-G	SEPT14	c.134G>C	p.Arg45Thr	Missense	3/10	-
12-46285585-G-C	ARID2	c.4945G>C	p.Val1649Leu	Missense	17/21	-
18-50832036-G-A	DCC	c.2000G>A	p.Arg667His	Missense	13/29	-
10-105218243-C-T	CALHM1	c.266G>A	p.Arg89Gln	Missense	1/2	-
17-40452768-G-T	STAT5A	c.869G>T	p.Arg290Leu	Missense	9/20	-
17-40452768-G-A	STAT5A	c.869G>A	p.Arg290Gln	Missense	9/20	-
18-21492826-T-C	LAMA3	c.2483T>C	p.Met828Thr	Missense	19/38	-
12-52842643-C-T	KRT6B	c.1186G>A	p.Asp396Asn	Missense	6/9	-
13-39621897-T-A	NHLRC3	c.878T>A	p.Ile293Asn	Missense	7/7	-
1-146672745-T-C	FMO5	c.1172A>G	p.Gln391Arg	Missense	7/9	-
9-133759722-G-A	ABL1	c.2102G>A	p.Arg701Gln	Missense	11/11	-
1-152193195-G-C	HRNR	c.910C>G	p.Arg304Gly	Missense	3/3	-
17-80043134-G-A	FASN	c.4267C>T	p.Arg1423Cys	Missense	24/43	-
X-153690570-G-T	PLXNA3	c.1237G>T	p.Gly413Cys	Missense	4/33	-
X-153690570-G-A	PLXNA3	c.1237G>A	p.Gly413Ser	Missense	4/33	-
5-149677517-G-A	ARSI	c.970C>T	p.Arg324Trp	Missense	2/2	-
5-149677517-G-T	ARSI	c.970C>A	p.Arg324Arg	Synonymous	2/2	-
2-152346522-G-A	NEB	c.19799C>T	p.Thr6600Met	Missense	149/150	-
3-39230770-C-T	XIRP1	c.167G>A	p.Arg56His	Missense	2/2	-
21-30250573-G-T	N6AMT1	c.479C>A	p.Pro160Gln	Missense	5/6	-
21-30250573-G-A	N6AMT1	c.479C>T	p.Pro160Leu	Missense	5/6	-
2-238287746-C-T	COL6A3	c.2030G>A	p.Arg677His	Missense	6/44	-
16-20429546-C-T	ACSM5	c.370C>T	p.Arg124Trp	Missense	3/14	-
2-238287746-C-A	COL6A3	c.2030G>T	p.Arg677Leu	Missense	6/44	-
12-40713899-T-C	LRRK2	c.4937T>C	p.Met1646Thr	Missense	34/51	-
11-800563-C-T	PIDD1	c.2021G>A	p.Arg674His	Missense	12/16	-
4-8620201-C-G	CPZ	c.1516C>G	p.Pro506Ala	Missense	9/10	-
20-44639599-C-T	MMP9	c.559C>T	p.Leu187Phe	Missense	4/13	-
8-100155318-G-A	VPS13B	c.1768G>A	p.Ala590Thr	Missense	13/62	-
19-42406469-A-G	ARHGEF1	c.1505A>G	p.Tyr502Cys	Missense	16/29	-
19-42406469-A-C	ARHGEF1	c.1505A>C	p.Tyr502Ser	Missense	16/29	-
13-32893342-C-G	BRCA2	c.196C>G	p.Gln66Glu	Missense	3/27	-
18-28992884-T-G	DSG4	c.2449T>G	p.Ser817Ala	Missense	16/16	-
6-20490428-G-A	E2F3	c.772G>A	p.Asp258Asn	Missense	7/7	-
16-22268969-C-T	EEF2K	c.907C>T	p.Arg303Cys	Missense	9/18	-
2-140990879-T-C	LRP1B	c.13676A>G	p.Asn4559Ser	Missense	91/91	-
14-94394770-C-T	FAM181A	c.325C>T	p.Arg109Cys	Missense	3/3	-
2-179613191-T-C	TTN	c.10360+4660A>G	-	IntronicSNV	-	45/311
3-183772604-C-T	HTR3C	c.163C>T	p.Arg55Cys	Missense	2/9	-
12-105431901-G-A	ALDH1L2	c.2125C>T	p.Leu709Phe	Missense	18/23	-
3-47908815-G-A	MAP4	c.2987C>T	p.Ser996Phe	Missense	15/19	-
20-61981555-G-A	CHRNA4	c.1208C>T	p.Pro403Leu	Missense	5/6	-
17-45221273-A-C	CDC27	c.1164T>G	p.Phe388Leu	Missense	10/19	-
16-20429546-C-A	ACSM5	c.370C>A	p.Arg124Arg	Synonymous	3/14	-
17-39506824-G-A	KRT33A	c.196C>T	p.Arg66Cys	Missense	1/7	-
10-3183003-G-A	PITRM1	c.2650C>T	p.Leu884Phe	Missense	24/27	-
5-80109479-T-G	MSH3	c.2732T>G	p.Leu911Trp	Missense	20/24	-
13-32912359-A-C	BRCA2	c.3867A>C	p.Lys1289Asn	Missense	11/27	-
13-32912359-A-T	BRCA2	c.3867A>T	p.Lys1289Asn	Missense	11/27	-
X-16142093-G-C	GRPR	c.17G>C	p.Cys6Ser	Missense	1/3	-
22-36691696-A-G	MYH9	c.3340T>C	p.Ser1114Pro	Missense	26/41	-
13-41134399-G-A	FOXO1	c.1229C>T	p.Pro410Leu	Missense	2/3	-
1-3683159-A-C	CCDC27	c.1513A>C	p.Asn505His	Missense	9/12	-
13-32906840-G-GCG	BRCA2	c.1225_1226insCG	p.Glu409Alafs*22	Frameshift	10/27	-
13-32907114-GT-AG	BRCA2	c.1499_1500delGTinsAG	p.Gly500Glu	Missense	10/27	-
11-14913631-G-A	CYP2R1	c.121C>T	p.Pro41Ser	Missense	1/5	-
1-15870933-G-A	DNAJC16	c.614G>A	p.Arg205His	Missense	5/15	-
1-15870933-G-C	DNAJC16	c.614G>C	p.Arg205Pro	Missense	5/15	-
1-15870933-G-T	DNAJC16	c.614G>T	p.Arg205Leu	Missense	5/15	-
1-167345342-A-G	POU2F1	c.668A>G	p.Asn223Ser	Missense	7/16	-
10-52595978-A-G	A1CF	c.460T>C	p.Ser154Pro	Missense	6/13	-
17-7579455-C-T	TP53	c.232G>A	p.Ala78Thr	Missense	4/11	-
17-37876083-G-T	ERBB2	c.1942G>T	p.Ala648Ser	Missense	16/27	-
11-116636108-G-A	BUD13	c.292C>T	p.Arg98Cys	Missense	3/10	-
6-33372831-T-C	KIFC1	c.959T>C	p.Val320Ala	Missense	7/11	-
11-1769085-G-A	IFITM10	c.349C>T	p.Arg117Trp	Missense	2/3	-
17-8644974-G-A	CCDC42	c.310C>T	p.Arg104Trp	Missense	4/7	-
3-188327604-C-T	LPP	c.1085C>T	p.Ala362Val	Missense	6/11	-
12-124393917-C-G	DNAH10	c.9571C>G	p.Pro3191Ala	Missense	57/78	-
19-7685787-G-A	XAB2	c.1916C>T	p.Ala639Val	Missense	14/19	-
17-37881314-C-G	ERBB2	c.2506C>G	p.Leu836Val	Missense	21/27	-
6-32551955-G-T	HLA-DRB1	c.301C>A	p.Arg101Arg	Synonymous	2/6	-
3-38357067-T-C	SLC22A14	c.1397T>C	p.Leu466Pro	Missense	8/10	-
3-38357067-T-A	SLC22A14	c.1397T>A	p.Leu466His	Missense	8/10	-
12-30877343-T-C	CAPRIN2	c.1948A>G	p.Thr650Ala	Missense	10/17	-
4-1746456-C-A	TACC3	c.2348C>A	p.Ala783Asp	Missense	15/16	-
15-55652244-G-A	CCPG1	c.1727C>T	p.Ala576Val	Missense	8/8	-
6-32551955-G-C	HLA-DRB1	c.301C>G	p.Arg101Gly	Missense	2/6	-
6-32551955-G-A	HLA-DRB1	c.301C>T	p.Arg101Trp	Missense	2/6	-
17-8638536-T-A	CCDC42	c.751A>T	p.Lys251*	Nonsense	6/7	-
15-51675980-A-G	GLDN	c.434-2A>G	-	IntronicSNV	-	3/9
7-158829449-C-T	VIPR2	c.742G>A	p.Gly248Arg	Missense	7/13	-
15-53081265-G-T	ONECUT1	c.817C>A	p.Pro273Thr	Missense	1/2	-
19-10334725-A-T	S1PR2	c.857T>A	p.Val286Asp	Missense	2/2	-
19-10334725-A-G	S1PR2	c.857T>C	p.Val286Ala	Missense	2/2	-
8-13072158-C-G	DLC1	c.1348+90620G>C	-	IntronicSNV	-	5/17
8-13072158-C-A	DLC1	c.1348+90620G>T	-	IntronicSNV	-	5/17
12-52845481-G-A	KRT6B	c.382C>T	p.Pro128Ser	Missense	1/9	-
13-32899276-C-T	BRCA2	c.380C>T	p.Ala127Val	Missense	4/27	-
1-26608831-C-T	UBXN11	c.1423G>A	p.Gly475Ser	Missense	15/15	-
11-62259213-G-C	AHNAK	c.433C>G	p.Pro145Ala	Missense	5/6	-
19-49685865-G-A	TRPM4	c.1294G>A	p.Ala432Thr	Missense	11/25	-
14-24587680-G-A	DCAF11	c.661G>A	p.Val221Ile	Missense	7/15	-
11-64575044-C-T	MEN1	c.778G>A	p.Glu260Lys	Missense	4/10	-
18-63492032-A-G	CDH7	c.946A>G	p.Lys316Glu	Missense	6/12	-
7-107570040-A-G	LAMB1	c.4562T>C	p.Ile1521Thr	Missense	30/34	-
2-113513557-C-T	CKAP2L	c.1391G>A	p.Arg464Gln	Missense	4/9	-
13-103520565-A-G	ERCC5	c.2636A>G	p.Asn879Ser	Missense	12/15	-
12-44130331-C-T	PUS7L	c.1578G>A	p.Met526Ile	Missense	7/9	-
2-175432636-G-A	WIPF1	c.1295C>T	p.Pro432Leu	Missense	6/8	-
1-158639328-C-T	SPTA1	c.1703G>A	p.Arg568His	Missense	14/52	-
1-158639328-C-G	SPTA1	c.1703G>C	p.Arg568Pro	Missense	14/52	-
11-3660256-C-A	ART5	c.797G>T	p.Arg266Met	Missense	3/4	-
19-39016135-A-G	RYR1	c.10619A>G	p.Tyr3540Cys	Missense	71/106	-
8-134251279-G-A	NDRG1	c.1027C>T	p.Arg343Cys	Missense	16/16	-
12-662412-G-C	B4GALNT3	c.1323G>C	p.Glu441Asp	Missense	14/20	-
6-11213709-T-C	NEDD9	c.264A>G	p.Gln88Gln	Synonymous	2/7	-
6-11213709-T-A	NEDD9	c.264A>T	p.Gln88His	Missense	2/7	-
17-37264441-G-A	PLXDC1	c.527C>T	p.Ala176Val	Missense	5/14	-
7-44152266-C-T	AEBP1	c.2327C>T	p.Ala776Val	Missense	18/21	-
8-17541943-T-G	MTUS1	c.2732A>C	p.Lys911Thr	Missense	7/15	-
10-103826484-G-A	HPS6	c.1253G>A	p.Gly418Asp	Missense	1/1	-
18-47109955-A-G	LIPG	c.1187A>G	p.Asn396Ser	Missense	8/10	-
18-47109955-A-C	LIPG	c.1187A>C	p.Asn396Thr	Missense	8/10	-
2-136262011-A-G	ZRANB3	c.49T>C	p.Cys17Arg	Missense	2/21	-
2-186665996-C-G	FSIP2	c.11963C>G	-	missense_variant	17/23	-
6-35201057-A-G	SCUBE3	c.691A>G	p.Thr231Ala	Missense	6/22	-
2-186665996-C-T	FSIP2	c.11963C>T	-	missense_variant	17/23	-
10-92675322-G-A	ANKRD1	c.827C>T	p.Ala276Val	Missense	8/9	-
17-18025140-C-A	MYO15A	c.3026C>A	p.Pro1009His	Missense	2/66	-
17-18025140-C-G	MYO15A	c.3026C>G	p.Pro1009Arg	Missense	2/66	-
4-69811110-A-T	UGT2A3	c.778T>A	p.Trp260Arg	Missense	2/6	-
4-69811110-A-C	UGT2A3	c.778T>G	p.Trp260Gly	Missense	2/6	-
1-20027301-G-A	TMCO4	c.1342C>T	p.Arg448Trp	Missense	14/16	-
1-45797139-G-A	MUTYH	c.1267C>T	p.Arg423Cys	Missense	13/16	-
10-50824106-C-G	CHAT	c.287-442C>G	-	IntronicSNV	-	1/14
4-6862665-G-A	KIAA0232	c.556G>A	p.Val186Ile	Missense	7/10	-
10-50824106-C-A	CHAT	c.287-442C>A	-	IntronicSNV	-	1/14
1-11733363-C-A	FBXO6	c.539C>A	p.Thr180Asn	Missense	5/6	-
10-27687638-C-T	PTCHD3	c.1889G>A	p.Arg630Gln	Missense	4/4	-
2-187540395-G-A	ITGAV	c.2771G>A	p.Ser924Asn	Missense	27/30	-
17-7573006-GTGGCTGTAGGAGACAGAAGCAGGGAGGAGAGATGACATCACATGAGTGAGAGGGTCTGT-G	TP53	c.1099_1103del923	-	Multi:SpliceDonorDeletion,SpliceAcceptorDeletion	11/11	10/10
X-78618948-G-C	ITM2A	c.215C>G	p.Ala72Gly	Missense	2/6	-
X-78618948-G-A	ITM2A	c.215C>T	p.Ala72Val	Missense	2/6	-
20-43836950-G-C	SEMG1	c.1012G>C	p.Glu338Gln	Missense	2/3	-
17-37879577-T-G	ERBB2	c.1952T>G	p.Leu651Arg	Missense	17/27	-
8-17500162-T-A	PDGFRL	c.980T>A	p.Ile327Asn	Missense	7/7	-
8-17500162-T-C	PDGFRL	c.980T>C	p.Ile327Thr	Missense	7/7	-
X-140993258-A-T	MAGEC1	c.68A>T	p.Gln23Leu	Missense	4/4	-
6-33283594-G-A	ZBTB22	c.1100C>T	p.Pro367Leu	Missense	2/2	-
19-40895808-A-G	HIPK4	c.2T>C	p.Met1Thr	Missense	1/4	-
2-27724663-A-G	GCKR	c.644+567A>G	-	IntronicSNV	-	8/18
13-32900715-C-T	BRCA2	c.596C>T	p.Ala199Val	Missense	7/27	-
6-32032790-G-A	TNXB	c.6649C>T	p.Pro2217Ser	Missense	19/44	-
1-206905941-G-T	MAPKAPK2	c.*505G>T	-	3-UTRSNV	10/10	-
17-37873661-C-T	ERBB2	c.1826C>T	p.Ser609Phe	Missense	15/27	-
2-187540395-G-T	ITGAV	c.2771G>T	p.Ser924Ile	Missense	27/30	-
2-97757290-C-T	FAHD2B	c.154G>A	p.Val52Ile	Missense	2/8	-
10-103826484-G-T	HPS6	c.1253G>T	p.Gly418Val	Missense	1/1	-
3-128852936-T-C	ISY1-RAB43	c.644A>G	p.Tyr215Cys	Missense	9/13	-
14-105169758-C-T	INF2	c.634C>T	p.Arg212Cys	Missense	4/23	-
2-239013472-G-A	ESPNL	c.661G>A	p.Val221Ile	Missense	3/9	-
6-152757224-G-T	SYNE1	c.4162C>A	p.Arg1388Arg	Synonymous	33/146	-
13-39621965-G-A	NHLRC3	c.946G>A	p.Asp316Asn	Missense	7/7	-
13-39621965-G-T	NHLRC3	c.946G>T	p.Asp316Tyr	Missense	7/7	-
14-105609442-C-T	JAG2	c.3307G>A	p.Val1103Met	Missense	26/26	-
20-5935893-A-G	MCM8	c.482A>G	p.His161Arg	Missense	5/19	-
5-177637232-C-T	HNRNPAB	c.788-322C>T	-	IntronicSNV	-	6/6
17-37868649-G-C	ERBB2	c.1096G>C	p.Gly366Arg	Missense	9/27	-
20-47865924-T-C	ZNFX1	c.3637A>G	p.Ile1213Val	Missense	14/14	-
6-148865088-C-T	SASH1	c.2482C>T	p.Pro828Ser	Missense	18/20	-
8-30916058-A-G	WRN	c.95A>G	p.Lys32Arg	Missense	2/35	-
3-179689390-G-C	PEX5L	c.85C>G	p.Gln29Glu	Missense	2/15	-
11-62302555-G-A	AHNAK	c.262C>T	p.Arg88Cys	Missense	4/6	-
7-100839291-T-A	MOGAT3	c.962A>T	p.Gln321Leu	Missense	7/7	-
17-76481041-A-C	DNAH17	c.7558T>G	p.Phe2520Val	Missense	48/81	-
12-121879022-C-T	KDM2B	c.3299G>A	p.Arg1100Gln	Missense	20/23	-
17-18027809-C-T	MYO15A	c.3622C>T	p.Arg1208Cys	Missense	3/66	-
18-74091461-T-C	ZNF516	c.2609A>G	p.His870Arg	Missense	4/8	-
14-77732925-T-C	NGB	c.410A>G	p.Tyr137Cys	Missense	4/4	-
9-135977479-G-C	RALGDS	c.2057C>G	p.Ser686Cys	Missense	15/18	-
2-30987041-G-C	CAPN13	c.656C>G	p.Ala219Gly	Missense	6/23	-
19-9082456-G-T	MUC16	c.9359C>A	p.Thr3120Asn	Missense	1/84	-
22-46688704-C-T	TTC38	c.1333C>T	p.Arg445Cys	Missense	14/14	-
15-90997745-G-A	IQGAP1	c.1573G>A	p.Val525Met	Missense	14/38	-
22-38121652-C-G	TRIOBP	c.3089C>G	p.Pro1030Arg	Missense	7/24	-
8-38677346-C-T	TACC1	c.584C>T	p.Ala195Val	Missense	3/13	-
7-23224779-G-GG	NUPL2	c.212_212dup	p.Ser72Glnfs*13	Frameshift	2/7	-
11-3660256-C-T	ART5	c.797G>A	p.Arg266Lys	Missense	3/4	-
1-229663025-C-G	ABCB10	c.1676G>C	p.Arg559Pro	Missense	9/13	-
1-229663025-C-A	ABCB10	c.1676G>T	p.Arg559Leu	Missense	9/13	-
1-229663025-C-T	ABCB10	c.1676G>A	p.Arg559His	Missense	9/13	-
16-1388672-C-T	BAIAP3	c.122C>T	p.Thr41Met	Missense	2/33	-
16-1388672-C-G	BAIAP3	c.122C>G	p.Thr41Arg	Missense	2/33	-
20-35740732-A-G	MROH8	c.2809T>C	-	missense_variant	21/25	-
20-8737719-G-A	PLCB1	c.2550G>A	p.Glu850Glu	Synonymous	24/32	-
17-5012622-C-T	ZNF232	c.498+67G>A	-	IntronicSNV	-	3/4
2-198948627-G-A	PLCL1	c.386G>A	p.Arg129His	Missense	2/6	-
17-7579536-TC-T	TP53	c.151delG	p.Glu51Asnfs*72	Frameshift	4/11	-
13-39621897-T-C	NHLRC3	c.878T>C	p.Ile293Thr	Missense	7/7	-
17-7579536-C-A	TP53	c.151G>T	p.Glu51*	Nonsense	4/11	-
16-2120559-G-A	TSC2	c.1819G>A	p.Ala607Thr	Missense	17/42	-
8-8235510-G-A	PRAG1	c.409C>T	p.Arg137*	Nonsense	3/6	-
8-8235510-G-C	PRAG1	c.409C>G	p.Arg137Gly	Missense	3/6	-
13-32913026-CGT-TGG	BRCA2	c.4534_4536delCGTinsTGG	p.Arg1512Trp	Missense	11/27	-
14-73733285-G-A	PAPLN	c.3259G>A	p.Ala1087Thr	Missense	23/26	-
1-146684095-T-C	FMO5	c.496A>G	p.Lys166Glu	Missense	5/9	-
21-40717137-C-T	HMGN1	c.190G>A	p.Glu64Lys	Missense	5/6	-
6-33282922-T-C	ZBTB22	c.1772A>G	p.Glu591Gly	Missense	2/2	-
4-178283446-G-T	NEIL3	c.1639G>T	p.Ala547Ser	Missense	10/10	-
2-128522189-T-C	WDR33	c.626+213A>G	-	IntronicSNV	-	6/21
1-158589121-G-C	SPTA1	c.6421C>G	p.Arg2141Gly	Missense	45/52	-
1-158589121-G-A	SPTA1	c.6421C>T	p.Arg2141Trp	Missense	45/52	-
1-158589121-G-T	SPTA1	c.6421C>A	p.Arg2141Arg	Synonymous	45/52	-
12-124402341-C-T	DNAH10	c.10859C>T	p.Thr3620Ile	Missense	63/78	-
1-209801479-C-T	LAMB3	c.1189G>A	p.Gly397Arg	Missense	11/23	-
10-3181157-G-C	PITRM1	c.2859C>G	p.Ile953Met	Missense	25/27	-
1-54605319-G-GCC	CDCP2	c.1223_1224insGG	p.Met409Alafs*2	Frameshift	5/5	-
6-150005429-G-C	LATS1	c.796C>G	p.Pro266Ala	Missense	4/8	-
6-150005429-G-A	LATS1	c.796C>T	p.Pro266Ser	Missense	4/8	-
6-150005429-G-T	LATS1	c.796C>A	p.Pro266Thr	Missense	4/8	-
1-147084683-A-G	BCL9	c.55A>G	p.Ser19Gly	Missense	5/10	-
2-125504881-T-C	CNTNAP5	c.2150T>C	p.Val717Ala	Missense	14/24	-
12-31820718-C-G	ETFBKMT	c.583C>G	p.Leu195Val	Missense	4/4	-
10-104359297-G-T	SUFU	c.1018G>T	p.Ala340Ser	Missense	8/12	-
22-40364122-G-T	GRAP2	c.536G>T	p.Arg179Leu	Missense	6/8	-
22-40364122-G-A	GRAP2	c.536G>A	p.Arg179Gln	Missense	6/8	-
8-144620334-C-G	ZC3H3	c.1203G>C	p.Lys401Asn	Missense	2/12	-
17-37864640-AGG-TGT	ERBB2	c.292_294delAGGinsTGT	p.Arg98Cys	Missense	3/27	-
12-31820718-C-T	ETFBKMT	c.583C>T	p.Leu195Phe	Missense	4/4	-
20-32255678-A-T	ACTL10	c.375A>T	p.Glu125Asp	Missense	1/1	-
9-98011497-G-A	FANCC	c.77C>T	p.Ser26Phe	Missense	2/15	-
12-65448985-C-T	WIF1	c.931G>A	p.Glu311Lys	Missense	9/10	-
10-13166053-A-T	OPTN	c.941A>T	p.Gln314Leu	Missense	8/14	-
1-34330137-C-T	CSMD2	c.801-17540G>A	-	IntronicSNV	-	5/69
13-25280563-C-A	ATP12A	c.2131C>A	p.Gln711Lys	Missense	15/23	-
17-7579867-TGACT-T	TP53	c.45_48delTCAG	p.Ser15Argfs*28	Frameshift	2/11	-
17-37882871-TC-CT	ERBB2	c.2929_2930delTCinsCT	p.Ser977Leu	Missense	24/27	-
1-152277797-C-G	FLG	c.9565G>C	p.Ala3189Pro	Missense	3/3	-
17-37866369-C-T	ERBB2	c.674C>T	p.Ala225Val	Missense	6/27	-
11-108032676-G-A	NPAT	c.3137C>T	p.Pro1046Leu	Missense	17/18	-
22-45204203-C-T	PRR5-ARHGAP8	c.550C>T	p.Leu184Leu	Synonymous	6/15	-
13-32899235-GA-G	BRCA2	c.339delA	p.Arg113Serfs*8	Frameshift	4/27	-
17-37856541-C-T	ERBB2	c.50C>T	p.Pro17Leu	Missense	1/27	-
13-114309237-C-T	ATP4B	c.133G>A	p.Val45Met	Missense	2/7	-
2-197767367-C-T	PGAP1	c.749G>A	p.Arg250His	Missense	5/27	-
1-152277797-C-A	FLG	c.9565G>T	p.Ala3189Ser	Missense	3/3	-
17-76118721-G-A	TMC6	c.1192C>T	p.Arg398Cys	Missense	10/20	-
17-7579548-G-C	TP53	c.139C>G	p.Pro47Ala	Missense	4/11	-
17-7579548-G-A	TP53	c.139C>T	p.Pro47Ser	Missense	4/11	-
6-83900694-T-C	PGM3	c.38A>G	p.His13Arg	Missense	2/13	-
4-129770150-G-T	JADE1	c.312G>T	p.Glu104Asp	Missense	5/9	-
7-44156490-C-T	POLD2	c.706G>A	p.Ala236Thr	Missense	6/11	-
13-23913826-C-T	SACS	c.4189G>A	p.Glu1397Lys	Missense	10/10	-
13-23913826-C-G	SACS	c.4189G>C	p.Glu1397Gln	Missense	10/10	-
12-68720687-G-A	MDM1	c.248C>T	p.Ser83Leu	Missense	3/3	-
4-90816203-G-T	MMRN1	c.81G>T	p.Trp27Cys	Missense	1/8	-
3-180334078-A-AA	CCDC39	c.2660_2660dup	p.Ser888Ilefs*6	Frameshift	19/20	-
3-186330934-A-T	AHSG	c.4A>T	p.Lys2*	Nonsense	1/7	-
17-45214698-C-G	CDC27	c.1751G>C	p.Ser584Thr	Missense	14/19	-
19-48602951-C-A	PLA2G4C	c.454G>T	p.Val152Phe	Missense	5/17	-
1-6639073-G-A	TAS1R1	c.1955G>A	p.Arg652His	Missense	6/6	-
17-45234430-A-G	CDC27	c.691T>C	p.Ser231Pro	Missense	7/19	-
1-6639073-G-T	TAS1R1	c.1955G>T	p.Arg652Leu	Missense	6/6	-
11-122945462-G-C	CLMP	c.769C>G	p.Arg257Gly	Missense	6/7	-
12-117691500-C-T	NOS1	c.2591G>A	p.Gly864Asp	Missense	17/29	-
3-121388135-C-T	GOLGB1	c.9230G>A	p.Arg3077His	Missense	18/22	-
16-20976519-C-T	DNAH3	c.8687G>A	p.Arg2896His	Missense	53/62	-
9-121929726-G-A	BRINP1	c.1922C>T	p.Ser641Leu	Missense	8/8	-
9-35740902-C-T	GBA2	c.946G>A	p.Gly316Arg	Missense	5/17	-
4-99993787-A-T	ADH5	c.1037T>A	p.Val346Glu	Missense	8/9	-
5-41007422-A-C	MROH2B	c.3743T>G	p.Leu1248Arg	Missense	34/42	-
9-35740902-C-G	GBA2	c.946G>C	p.Gly316Arg	Missense	5/17	-
7-132193335-A-G	PLXNA4	c.118T>C	p.Phe40Leu	Missense	3/5	-
13-32906600-AG-CC	BRCA2	c.985_986delAGinsCC	p.Arg329Pro	Missense	10/27	-
13-32906600-AG-CA	BRCA2	c.985_986delAGinsCA	p.Arg329Gln	Missense	10/27	-
7-891100-G-T	SUN1	c.509-487G>T	-	IntronicSNV	-	5/17
7-21945240-G-A	CDCA7L	c.931C>T	p.Arg311Trp	Missense	7/10	-
20-5966763-A-G	MCM8	c.2149A>G	p.Ile717Val	Missense	16/19	-
17-7572982-AGAC-A	TP53	c.1125_1127delGTC	p.Gln375_ser376delinsHis	MultiAAMissense	11/11	-
1-53668099-C-T	CPT2	c.338C>T	p.Ser113Leu	Missense	3/5	-
17-37866453-T-A	ERBB2	c.758T>A	p.Leu253Gln	Missense	6/27	-
6-150022977-G-A	LATS1	c.286C>T	p.Arg96Trp	Missense	2/8	-
17-41981843-G-C	MPP2	c.1-15C>G	-	5-UTRSNV	2/13	-
17-41981843-G-A	MPP2	c.1-15C>T	-	5-UTRSNV	2/13	-
4-169632895-C-G	PALLD	c.1785C>G	p.Ser595Arg	Missense	10/21	-
11-5364049-G-C	OR51B5	c.706C>G	p.Leu236Val	Missense	5/5	-
4-8605860-C-T	CPZ	c.621C>T	p.Asp207Asp	Synonymous	3/10	-
X-57515249-G-A	FAAH2	c.1483G>A	p.Gly495Arg	Missense	11/11	-
15-57484419-C-T	TCF12	c.454C>T	p.Pro152Ser	Missense	7/20	-
2-182542838-G-T	NEUROD1	c.750C>A	p.Ser250Arg	Missense	2/2	-
2-182542838-G-A	NEUROD1	c.750C>T	p.Ser250Ser	Synonymous	2/2	-
6-152694231-C-T	SYNE1	c.9448G>A	p.Ala3150Thr	Missense	59/146	-
4-8605860-C-A	CPZ	c.621C>A	p.Asp207Glu	Missense	3/10	-
17-37864770-A-C	ERBB2	c.422A>C	p.Gln141Pro	Missense	3/27	-
16-16142079-G-T	ABCC1	c.1299G>T	p.Arg433Ser	Missense	10/31	-
9-131397116-C-G	WDR34	c.1066G>C	p.Gly356Arg	Missense	7/9	-
11-121454211-G-A	SORL1	c.3625G>A	p.Gly1209Arg	Missense	26/48	-
X-140993747-C-T	MAGEC1	c.557C>T	p.Thr186Ile	Missense	4/4	-
1-15642964-G-C	FHAD1	c.1260+1G>C	-	IntronicSNV	-	9/30
11-6644232-C-T	DCHS1	c.8675G>A	p.Arg2892Gln	Missense	21/21	-
7-107570040-A-C	LAMB1	c.4562T>G	p.Ile1521Ser	Missense	30/34	-
20-3729011-C-T	HSPA12B	c.823C>T	p.Arg275Cys	Missense	8/13	-
10-32103189-C-T	ARHGAP12	c.1817G>A	p.Arg606His	Missense	13/19	-
9-132671178-A-G	FNBP1	c.1286T>C	p.Met429Thr	Missense	12/17	-
X-153693126-C-T	PLXNA3	c.1958C>T	p.Pro653Leu	Missense	10/33	-
9-134504021-G-A	RAPGEF1	c.881C>T	p.Ala294Val	Missense	8/24	-
7-95906535-C-T	SLC25A13	c.185G>A	p.Ser62Asn	Missense	3/18	-
17-37868669-GG-G	ERBB2	c.1116delG	p.Ser373Alafs*58	Frameshift	9/27	-
19-9076006-A-G	MUC16	c.11440T>C	p.Ser3814Pro	Missense	3/84	-
19-758613-G-A	MISP	c.1667G>A	p.Arg556His	Missense	2/5	-
17-7579577-G-A	TP53	c.110C>T	p.Ser37Phe	Missense	4/11	-
2-27729379-C-G	GCKR	c.901C>G	p.Arg301Gly	Missense	11/19	-
2-27729379-C-T	GCKR	c.901C>T	p.Arg301*	Nonsense	11/19	-
8-124094998-G-T	TBC1D31	c.281G>T	p.Arg94Leu	Missense	3/22	-
8-124094998-G-A	TBC1D31	c.281G>A	p.Arg94His	Missense	3/22	-
16-89254538-G-A	CDH15	c.823G>A	p.Gly275Arg	Missense	7/14	-
15-41148092-C-T	SPINT1	c.1120C>T	p.His374Tyr	Missense	9/11	-
12-18892040-A-C	CAPZA3	c.838A>C	p.Met280Leu	Missense	1/1	-
1-235715488-C-T	GNG4	c.149G>A	p.Arg50Gln	Missense	3/3	-
1-54605319-G-GC	CDCP2	c.1223_1224insG	p.Met409Hisfs*81	Frameshift	5/5	-
1-54605319-G-GT	CDCP2	c.1223_1224insA	p.Met409Hisfs*81	Frameshift	5/5	-
1-226037619-G-A	TMEM63A	c.2065C>T	p.Arg689Cys	Missense	21/25	-
15-90167197-G-T	TICRR	c.3656G>T	p.Ser1219Ile	Missense	20/22	-
5-93990395-A-C	SLF1	c.1093A>C	p.Lys365Gln	Missense	9/21	-
1-235884023-G-A	LYST	c.9498C>T	p.Phe3166Phe	Synonymous	40/53	-
4-42445607-G-A	ATP8A1	c.3098C>T	p.Pro1033Leu	Missense	33/37	-
17-7579485-C-T	TP53	c.202G>A	p.Glu68Lys	Missense	4/11	-
11-126162947-C-G	TIRAP	c.643C>G	p.Arg215Gly	Missense	5/5	-
11-126162947-C-A	TIRAP	c.643C>A	p.Arg215Ser	Missense	5/5	-
11-126162947-C-T	TIRAP	c.643C>T	p.Arg215Cys	Missense	5/5	-
17-73559233-G-A	LLGL2	c.667G>A	p.Val223Met	Missense	7/25	-
17-37872153-G-T	ERBB2	c.1474G>T	p.Ala492Ser	Missense	12/27	-
19-46332369-C-T	SYMPK	c.1844G>A	p.Arg615His	Missense	14/27	-
19-46332369-C-A	SYMPK	c.1844G>T	p.Arg615Leu	Missense	14/27	-
1-14107658-A-T	PRDM2	c.3368A>T	p.Asp1123Val	Missense	8/10	-
2-114500349-C-T	SLC35F5	c.670G>A	p.Glu224Lys	Missense	7/16	-
2-114500349-C-A	SLC35F5	c.670G>T	p.Glu224*	Nonsense	7/16	-
1-95538342-C-T	ALG14	c.113G>A	p.Ser38Asn	Missense	1/4	-
9-123673673-T-C	TRAF1	c.824A>G	p.Asn275Ser	Missense	6/8	-
12-68724924-T-TT	MDM1	c.98_98dup	p.Tyr34Valfs*7	Frameshift	2/3	-
2-113593794-G-T	IL1B	c.13C>A	p.Pro5Thr	Missense	2/7	-
18-19154339-T-C	ESCO1	c.466A>G	p.Lys156Glu	Missense	4/12	-
8-15605938-C-A	TUSC3	c.992C>A	p.Ser331*	Nonsense	9/11	-
8-15605938-C-G	TUSC3	c.992C>G	p.Ser331*	Nonsense	9/11	-
1-152192121-G-A	HRNR	c.1984C>T	p.Arg662Cys	Missense	3/3	-
1-152192121-G-C	HRNR	c.1984C>G	p.Arg662Gly	Missense	3/3	-
1-242042364-A-G	EXO1	c.1828A>G	p.Ser610Gly	Missense	11/14	-
19-42879956-A-G	MEGF8	c.7366A>G	p.Thr2456Ala	Missense	41/41	-
19-48953603-G-T	GRWD1	c.502G>T	p.Val168Leu	Missense	4/7	-
17-37871558-G-A	ERBB2	c.1168G>A	p.Ala390Thr	Missense	10/27	-
17-37865670-C-T	ERBB2	c.539C>T	p.Ala180Val	Missense	4/27	-
12-18891466-C-A	CAPZA3	c.264C>A	p.Ser88Arg	Missense	1/1	-
1-167515428-G-A	CREG1	c.569C>T	p.Ala190Val	Missense	3/4	-
17-37884049-TC-CG	ERBB2	c.3520_3521delTCinsCG	p.Ser1174Arg	Missense	27/27	-
1-152192121-G-T	HRNR	c.1984C>A	p.Arg662Ser	Missense	3/3	-
1-242042364-A-C	EXO1	c.1828A>C	p.Ser610Arg	Missense	11/14	-
4-148546142-C-T	TMEM184C	c.479C>T	p.Pro160Leu	Missense	4/10	-
10-32308786-G-A	KIF5B	c.2306C>T	p.Thr769Met	Missense	20/26	-
22-23915761-C-T	IGLL1	c.334G>A	p.Ala112Thr	Missense	3/3	-
17-7578179-C-T	TP53	c.670G>A	p.Glu224Lys	Missense	6/11	-
17-7579506-C-T	TP53	c.181G>A	p.Asp61Asn	Missense	4/11	-
2-232894725-G-T	DIS3L2	c.301G>T	p.Ala101Ser	Missense	5/21	-
16-3534831-C-G	NAA60	c.705C>G	p.Gly235Gly	Synonymous	6/7	-
11-1775352-C-T	CTSD	c.844G>A	p.Gly282Arg	Missense	7/9	-
15-28358774-C-T	HERC2	c.13964G>A	p.Arg4655His	Missense	91/93	-
18-77679298-A-G	PQLC1	c.494T>C	p.Ile165Thr	Missense	5/6	-
1-160321967-C-T	NCSTN	c.967C>T	p.Arg323Cys	Missense	8/17	-
1-197111665-G-T	ASPM	c.1717C>A	p.Arg573Arg	Synonymous	3/28	-
13-36239272-G-T	NBEA	c.8350G>T	p.Val2784Phe	Missense	55/58	-
X-140993801-G-C	MAGEC1	c.611G>C	p.Arg204Pro	Missense	4/4	-
4-55964922-G-A	KDR	c.2315C>T	p.Ala772Val	Missense	16/30	-
13-32910431-CTGTT-C	BRCA2	c.1939_1942delTGTT	p.Cys647Hisfs*12	Frameshift	11/27	-
8-144589985-G-A	ZC3H3	c.1646C>T	p.Ser549Leu	Missense	4/12	-
17-76492005-C-A	DNAH17	c.5855G>T	p.Gly1952Val	Missense	38/81	-
X-132888183-G-A	GPC3	c.358C>T	p.Arg120Cys	Missense	3/8	-
11-17655816-G-C	OTOG	c.7504G>C	p.Gly2502Arg	Missense	43/55	-
22-29446480-G-C	ZNRF3	c.2311G>C	p.Gly771Arg	Missense	8/9	-
17-39324123-C-T	KRTAP4-3	c.302G>A	p.Arg101His	Missense	1/1	-
5-138739707-C-A	SPATA24	c.43G>T	p.Val15Leu	Missense	1/6	-
3-39226336-G-A	XIRP1	c.4601C>T	p.Thr1534Met	Missense	2/2	-
17-7573959-CCC-AGC	TP53	c.1066_1068delGGGinsAGC	p.Gly356Ser	Missense	10/11	-
1-235929555-G-A	LYST	c.5945C>T	p.Thr1982Ile	Missense	21/53	-
1-147084965-C-T	BCL9	c.337C>T	p.Pro113Ser	Missense	5/10	-
X-102755560-G-T	RAB40A	c.125C>A	p.Pro42Gln	Missense	3/3	-
X-102755560-G-A	RAB40A	c.125C>T	p.Pro42Leu	Missense	3/3	-
2-238289980-G-C	COL6A3	c.1475C>G	p.Thr492Ser	Missense	5/44	-
7-151853100-C-A	KMT2C	c.11855G>T	p.Arg3952Ile	Missense	46/59	-
X-24759542-A-G	POLA1	c.2249A>G	p.Lys750Arg	Missense	21/37	-
3-113082077-T-G	CFAP44	c.2849A>C	p.Glu950Ala	Missense	21/21	-
13-32890602-C-G	BRCA2	c.5C>G	p.Pro2Arg	Missense	2/27	-
6-32151427-G-A	AGER	c.260C>T	p.Pro87Leu	Missense	3/11	-
1-100949904-G-A	CDC14A	c.1034G>A	p.Arg345Gln	Missense	11/15	-
5-138739707-C-T	SPATA24	c.43G>A	p.Val15Met	Missense	1/6	-
17-72846368-C-T	GRIN2C	c.1468G>A	p.Val490Ile	Missense	6/13	-
13-32906537-T-C	BRCA2	c.922T>C	p.Phe308Leu	Missense	10/27	-
10-126716115-G-A	CTBP2	c.58+11451C>T	-	IntronicSNV	-	3/10
12-118199278-G-C	KSR2	c.524C>G	-	missense_variant	4/20	-
18-74091731-C-T	ZNF516	c.2339G>A	p.Arg780His	Missense	4/8	-
12-118199278-G-A	KSR2	c.524C>T	-	missense_variant	4/20	-
17-37879690-AGA-TGT	ERBB2	c.2065_2067delAGAinsTGT	p.Arg689Cys	Missense	17/27	-
19-52091068-G-T	ZNF175	c.1484G>T	p.Arg495Leu	Missense	5/5	-
19-52091068-G-A	ZNF175	c.1484G>A	p.Arg495Gln	Missense	5/5	-
5-178139380-C-T	ZNF354A	c.1499G>A	p.Gly500Glu	Missense	5/5	-
1-170129701-T-C	METTL11B	c.197T>C	p.Met66Thr	Missense	2/4	-
19-9082456-G-A	MUC16	c.9359C>T	p.Thr3120Ile	Missense	1/84	-
17-7578476-G-A	TP53	c.454C>T	p.Pro152Ser	Missense	5/11	-
6-170070759-G-C	WDR27	c.362C>G	p.Ser121Trp	Missense	4/26	-
6-170070759-G-T	WDR27	c.362C>A	p.Ser121*	Nonsense	4/26	-
10-102256987-C-T	SEC31B	c.2041G>A	p.Glu681Lys	Missense	17/26	-
5-112176819-C-T	APC	c.5528C>T	p.Pro1843Leu	Missense	16/16	-
15-89382103-G-C	ACAN	c.280G>C	p.Val94Leu	Missense	3/16	-
15-91310183-C-T	BLM	c.2237C>T	p.Ala746Val	Missense	10/22	-
6-111688947-T-A	REV3L	c.6044A>T	p.Glu2015Val	Missense	15/33	-
3-41949348-G-A	ULK4	c.1171C>T	p.Pro391Ser	Missense	12/37	-
10-104359297-G-C	SUFU	c.1018G>C	p.Ala340Pro	Missense	8/12	-
14-64066066-C-T	WDR89	c.595G>A	p.Asp199Asn	Missense	3/3	-
10-43882669-T-C	HNRNPF	c.664A>G	p.Ile222Val	Missense	4/4	-
13-61986858-A-C	PCDH20	c.1374T>G	p.Asp458Glu	Missense	2/2	-
7-95222201-T-C	PDK4	c.400A>G	p.Met134Val	Missense	4/11	-
19-35250448-C-T	ZNF599	c.1258G>A	p.Glu420Lys	Missense	4/4	-
22-39137513-C-T	SUN2	c.1195G>A	p.Val399Ile	Missense	10/18	-
7-121718017-T-C	AASS	c.2537A>G	p.His846Arg	Missense	23/24	-
X-140993747-C-G	MAGEC1	c.557C>G	p.Thr186Ser	Missense	4/4	-
11-1253691-C-T	MUC5B	c.1855C>T	p.Arg619Trp	Missense	16/49	-
11-1253691-C-G	MUC5B	c.1855C>G	p.Arg619Gly	Missense	16/49	-
16-4935694-C-A	PPL	c.2962G>T	p.Gly988Trp	Missense	22/22	-
1-43777350-G-A	TIE1	c.1342G>A	p.Val448Met	Missense	10/23	-
1-113637053-G-A	LRIG2	c.608G>A	p.Arg203Gln	Missense	5/18	-
1-6266749-C-T	RNF207	c.154C>T	p.Arg52Cys	Missense	2/18	-
19-9069507-G-T	MUC16	c.17939C>A	p.Thr5980Asn	Missense	3/84	-
19-55748011-C-T	PPP6R1	c.1988G>A	p.Arg663Gln	Missense	17/24	-
11-128354963-T-C	ETS1	c.485A>G	p.Tyr162Cys	Missense	5/8	-
2-179600787-T-C	TTN	c.10654A>G	p.Thr3552Ala	Missense	47/312	-
19-35250448-C-A	ZNF599	c.1258G>T	p.Glu420*	Nonsense	4/4	-
17-27896342-C-T	TP53I13	c.148C>T	p.Pro50Ser	Missense	3/7	-
17-37872848-TG-T	ERBB2	c.1727delG	p.Cys576Phefs*29	Frameshift	14/27	-
X-2871204-C-G	ARSE	c.410G>C	p.Gly137Ala	Missense	5/11	-
2-179597590-T-C	TTN	c.12581A>G	p.Lys4194Arg	Missense	52/312	-
X-2871204-C-A	ARSE	c.410G>T	p.Gly137Val	Missense	5/11	-
2-170030537-G-A	LRP2	c.10906C>T	p.Arg3636Trp	Missense	56/79	-
4-129891542-C-A	SCLT1	c.768G>T	p.Met256Ile	Missense	10/21	-
11-47363549-T-C	MYBPC3	c.1783A>G	p.Ile595Val	Missense	18/35	-
13-32900238-T-TG	BRCA2	c.426_427insG	-	SpliceAcceptorInsertion	5/27	-
18-34298542-G-A	FHOD3	c.2756G>A	p.Arg919Gln	Missense	16/25	-
10-50827796-C-G	CHAT	c.413C>G	p.Pro138Arg	Missense	3/15	-
1-216390763-G-T	USH2A	c.3123C>A	p.His1041Gln	Missense	15/21	-
17-33331503-G-A	LIG3	c.3008G>A	p.Arg1003Gln	Missense	20/20	-
7-111379198-G-C	DOCK4	c.5197C>G	p.Pro1733Ala	Missense	48/52	-
11-66460857-G-A	SPTBN2	c.4654C>T	p.Arg1552Cys	Missense	23/37	-
14-105609442-C-A	JAG2	c.3307G>T	p.Val1103Leu	Missense	26/26	-
7-117250575-G-C	CFTR	c.2991G>C	p.Leu997Phe	Missense	19/27	-
21-45711025-C-G	AIRE	c.927C>G	p.Ile309Met	Missense	8/14	-
4-184182568-A-G	WWC2	c.1792A>G	p.Ser598Gly	Missense	11/23	-
9-136595269-G-A	SARDH	c.731C>T	p.Thr244Met	Missense	5/21	-
13-32913076-C-G	BRCA2	c.4584C>G	p.Ser1528Arg	Missense	11/27	-
6-152757224-G-A	SYNE1	c.4162C>T	p.Arg1388Trp	Missense	33/146	-
17-48559671-C-T	RSAD1	c.694C>T	p.Arg232Trp	Missense	4/9	-
10-50827796-C-T	CHAT	c.413C>T	p.Pro138Leu	Missense	3/15	-
10-50827796-C-A	CHAT	c.413C>A	p.Pro138Gln	Missense	3/15	-
3-185214748-G-C	TMEM41A	c.141C>G	p.Asp47Glu	Missense	2/5	-
11-126162665-C-T	TIRAP	c.361C>T	p.Arg121Trp	Missense	5/5	-
3-50005855-G-A	RBM6	c.997G>A	p.Glu333Lys	Missense	3/21	-
10-95093661-G-C	MYOF	c.4573C>G	p.Arg1525Gly	Missense	42/54	-
14-65258486-G-A	SPTB	c.2755C>T	p.His919Tyr	Missense	14/35	-
X-140993885-C-T	MAGEC1	c.695C>T	p.Pro232Leu	Missense	4/4	-
10-95093661-G-A	MYOF	c.4573C>T	p.Arg1525Trp	Missense	42/54	-
6-32729613-T-C	HLA-DQB2	c.188A>G	p.Glu63Gly	Missense	2/5	-
11-108032167-T-C	NPAT	c.3646A>G	p.Asn1216Asp	Missense	17/18	-
7-121638042-A-G	PTPRZ1	c.1222A>G	p.Met408Val	Missense	10/30	-
18-46812845-T-G	DYM	c.905A>C	p.Asn302Thr	Missense	9/17	-
13-32907140-AGA-TGG	BRCA2	c.1525_1527delAGAinsTGG	p.Arg509Trp	Missense	10/27	-
12-117725949-C-T	NOS1	c.1057G>A	p.Val353Ile	Missense	5/29	-
16-31143814-G-A	PRSS8	c.641C>T	p.Pro214Leu	Missense	5/6	-
17-37868631-A-T	ERBB2	c.1078A>T	p.Asn360Tyr	Missense	9/27	-
9-78973431-G-A	PCSK5	c.5176G>A	p.Glu1726Lys	Missense	37/37	-
1-6528150-T-C	PLEKHG5	c.2746A>G	p.Thr916Ala	Missense	20/21	-
12-11285924-C-T	TAS2R30	c.920G>A	p.Arg307His	Missense	1/1	-
15-41308365-A-C	INO80	c.3323T>G	p.Val1108Gly	Missense	27/36	-
5-79026339-A-C	CMYA5	c.1751A>C	p.Glu584Ala	Missense	2/13	-
11-134062648-C-A	NCAPD3	c.1981G>T	p.Asp661Tyr	Missense	16/35	-
2-24260860-G-A	WDCP	c.1505C>T	p.Pro502Leu	Missense	2/4	-
13-32910603-CC-C	BRCA2	c.2111delC	p.Pro704Glnfs*26	Frameshift	11/27	-
19-40581579-G-A	ZNF780A	c.770C>T	p.Ser257Phe	Missense	6/6	-
7-111379198-G-A	DOCK4	c.5197C>T	p.Pro1733Ser	Missense	48/52	-
12-124907067-C-A	NCOR2	c.1363G>T	p.Ala455Ser	Missense	14/49	-
3-39108050-T-G	WDR48	c.280T>G	p.Ser94Ala	Missense	4/19	-
1-155013020-G-A	DCST1	c.451G>A	p.Val151Met	Missense	6/17	-
17-7577120-C-A	TP53	c.818G>T	p.Arg273Leu	Missense	8/11	-
17-7579472-G-A	TP53	c.215C>T	p.Pro72Leu	Missense	4/11	-
13-32900263-GTA-ATG	BRCA2	c.451_453delGTAinsATG	p.Val151Met	Missense	5/27	-
19-50491689-C-A	VRK3	c.1157G>T	p.Gly386Val	Missense	12/15	-
4-1729887-G-A	TACC3	c.758G>A	p.Gly253Asp	Missense	4/16	-
9-418173-A-C	DOCK8	c.3806A>C	p.Asn1269Thr	Missense	30/48	-
2-172935641-T-C	METAP1D	c.547T>C	p.Tyr183His	Missense	6/10	-
4-13603200-T-G	BOD1L1	c.5324A>C	p.Gln1775Pro	Missense	10/26	-
4-13603200-T-A	BOD1L1	c.5324A>T	p.Gln1775Leu	Missense	10/26	-
19-1057343-G-A	ABCA7	c.4795G>A	p.Val1599Met	Missense	35/47	-
1-20005587-C-T	HTR6	c.1049C>T	p.Ser350Leu	Missense	3/3	-
5-79031745-A-G	CMYA5	c.7157A>G	p.Gln2386Arg	Missense	2/13	-
12-117693813-C-T	NOS1	c.2532-2254G>A	-	IntronicSNV	-	16/28
12-18891703-C-T	CAPZA3	c.501C>T	p.Asn167Asn	Synonymous	1/1	-
5-79024949-G-A	CMYA5	c.361G>A	p.Val121Ile	Missense	2/13	-
7-47436435-C-T	TNS3	c.986G>A	p.Arg329His	Missense	16/31	-
7-47436435-C-G	TNS3	c.986G>C	p.Arg329Pro	Missense	16/31	-
7-47436435-C-A	TNS3	c.986G>T	p.Arg329Leu	Missense	16/31	-
3-52548787-C-T	STAB1	c.3749C>T	p.Ser1250Leu	Missense	35/69	-
1-233314839-C-T	PCNX2	c.3149G>A	p.Arg1050His	Missense	16/34	-
19-41515255-C-T	CYP2B6	c.777C>T	p.Ser259Ser	Synonymous	5/9	-
8-42167039-G-A	IKBKB	c.686+496G>A	-	IntronicSNV	-	7/20
1-94476377-C-T	ABCA4	c.5693G>A	p.Arg1898His	Missense	40/50	-
16-20963832-C-T	DNAH3	c.11111G>A	p.Arg3704Lys	Missense	56/62	-
15-62261612-T-C	VPS13C	c.2668A>G	p.Thr890Ala	Missense	26/83	-
19-9050232-C-T	MUC16	c.31399G>A	p.Gly10467Arg	Missense	5/84	-
2-239040065-G-A	ESPNL	c.2710G>A	p.Val904Met	Missense	9/9	-
20-30729619-G-A	TM9SF4	c.449G>A	p.Arg150Gln	Missense	5/18	-
3-48638472-T-C	UQCRC1	c.902A>G	p.Asn301Ser	Missense	8/13	-
22-19187327-T-C	CLTCL1	c.3791A>G	p.Gln1264Arg	Missense	24/33	-
17-7579524-GTGAACCATTGTTC-G	TP53	c.151_163del13	p.Glu51Leufs*68	Frameshift	4/11	-
22-45258168-G-A	PRR5-ARHGAP8	c.1388G>A	-	missense_variant	15/15	-
2-179479607-G-A	TTN	c.41023C>T	p.Pro13675Ser	Missense	209/312	-
2-179479607-G-C	TTN	c.41023C>G	p.Pro13675Ala	Missense	209/312	-
19-35758620-G-A	LSR	c.1840G>A	p.Glu614Lys	Missense	8/9	-
17-73729629-C-T	ITGB4	c.1513C>T	p.Arg505Trp	Missense	13/40	-
15-52186062-C-G	TMOD3	c.547C>G	p.Pro183Ala	Missense	6/10	-
5-160047528-C-A	ATP10B	c.2242G>T	p.Val748Leu	Missense	15/26	-
19-36036001-T-C	GAPDHS	c.1156T>C	p.Tyr386His	Missense	11/11	-
5-112228668-C-T	REEP5	c.352-5788G>A	-	IntronicSNV	-	3/4
5-112228668-C-A	REEP5	c.352-5788G>T	-	IntronicSNV	-	3/4
19-11363634-C-G	DOCK6	c.133G>C	p.Val45Leu	Missense	3/48	-
3-39425226-A-G	SLC25A38	c.11A>G	p.Asn4Ser	Missense	1/7	-
7-23016406-C-T	FAM126A	c.436G>A	p.Ala146Thr	Missense	6/11	-
17-8021612-C-A	ALOXE3	c.93G>T	p.Gln31His	Missense	2/16	-
19-11363634-C-T	DOCK6	c.133G>A	p.Val45Ile	Missense	3/48	-
17-11840819-G-T	DNAH9	c.12640G>T	p.Gly4214Cys	Missense	66/69	-
17-11840819-G-C	DNAH9	c.12640G>C	p.Gly4214Arg	Missense	66/69	-
17-48458188-G-A	EME1	c.1601G>A	p.Arg534His	Missense	9/9	-
17-48458188-G-C	EME1	c.1601G>C	p.Arg534Pro	Missense	9/9	-
18-50832036-G-T	DCC	c.2000G>T	p.Arg667Leu	Missense	13/29	-
4-77230712-G-T	FAM47E-STBD1	c.*386G>T	-	3-UTRSNV	7/7	-
1-26608831-C-A	UBXN11	c.1423G>T	p.Gly475Cys	Missense	15/15	-
1-85736519-G-T	BCL10	c.128C>A	p.Ala43Glu	Missense	2/3	-
3-50112609-G-T	RBM6	c.3117-25G>T	-	IntronicSNV	-	19/20
4-89318021-T-G	HERC6	c.906T>G	p.Tyr302*	Nonsense	7/22	-
4-89318021-T-A	HERC6	c.906T>A	p.Tyr302*	Nonsense	7/22	-
2-179600475-C-A	TTN	c.10966G>T	p.Ala3656Ser	Missense	47/312	-
2-179600475-C-G	TTN	c.10966G>C	p.Ala3656Pro	Missense	47/312	-
10-95085594-T-C	MYOF	c.5260A>G	p.Asn1754Asp	Missense	46/54	-
3-75787546-G-C	ZNF717	c.1228C>G	p.Leu410Val	Missense	5/5	-
18-2694682-G-A	SMCHD1	c.1031G>A	p.Arg344Gln	Missense	8/48	-
4-8613762-G-T	CPZ	c.1203G>T	p.Lys401Asn	Missense	7/10	-
17-38935980-C-T	KRT27	c.818G>A	p.Arg273Lys	Missense	4/8	-
19-17062930-G-A	CPAMD8	c.2498C>T	p.Ser833Phe	Missense	20/42	-
1-22846721-G-T	ZBTB40	c.3001G>T	p.Val1001Phe	Missense	14/18	-
12-117289603-A-G	RNFT2	c.1201-852A>G	-	IntronicSNV	-	10/10
11-93494810-C-T	C11orf54	c.754C>T	p.Arg252Cys	Missense	8/8	-
5-149449827-C-T	CSF1R	c.1237G>A	p.Gly413Ser	Missense	9/22	-
4-8613762-G-A	CPZ	c.1203G>A	p.Lys401Lys	Synonymous	7/10	-
7-99696247-C-T	MCM7	c.146G>A	p.Arg49Gln	Missense	5/14	-
1-160123000-G-A	ATP1A4	c.193G>A	p.Val65Met	Missense	2/22	-
12-2788668-C-G	CACNA1C	c.5150C>G	p.Ala1717Gly	Missense	42/47	-
7-100684773-C-A	MUC17	c.10076C>A	p.Thr3359Asn	Missense	3/13	-
12-2788668-C-T	CACNA1C	c.5150C>T	p.Ala1717Val	Missense	42/47	-
20-47558417-C-T	ARFGEF2	c.169C>T	p.Pro57Ser	Missense	3/39	-
9-124081138-G-C	GSN	c.1324G>C	p.Asp442His	Missense	9/17	-
20-1638293-A-T	SIRPG	c.68T>A	p.Leu23His	Missense	1/6	-
10-74594137-C-G	MCU	c.171C>G	p.Ser57Ser	Synonymous	2/8	-
17-7579438-CCGCC-C	TP53	c.247_250delGCGG	p.Ala83Profs*39	Frameshift	4/11	-
3-51673633-G-T	RAD54L2	c.2059G>T	p.Val687Phe	Missense	13/23	-
4-72363294-A-T	SLC4A4	c.1919A>T	p.Asn640Ile	Missense	13/23	-
1-248637549-A-G	OR2T3	c.898A>G	p.Lys300Glu	Missense	1/1	-
6-158485972-G-A	SYNJ2	c.1474G>A	p.Glu492Lys	Missense	11/27	-
10-74594137-C-T	MCU	c.171C>T	p.Ser57Ser	Synonymous	2/8	-
1-90179936-C-T	LRRC8C	c.1807C>T	p.Arg603Cys	Missense	3/3	-
10-95093661-G-T	MYOF	c.4573C>A	p.Arg1525Arg	Synonymous	42/54	-
3-58870326-T-G	C3orf67	c.285A>C	p.Lys95Asn	Missense	7/16	-
11-57296313-G-T	TIMM10	c.150C>A	p.Cys50*	Nonsense	3/3	-
5-82789493-G-A	VCAN	c.574G>A	p.Gly192Arg	Missense	4/15	-
16-2168022-C-A	PKD1	c.971G>T	p.Arg324Leu	Missense	5/46	-
4-79328846-G-T	FRAS1	c.4159G>T	p.Ala1387Ser	Missense	31/42	-
17-7577138-CG-AA	TP53	c.799_800delCGinsAA	p.Arg267Lys	Missense	8/11	-
17-74868887-C-T	MGAT5B	c.69-46C>T	-	IntronicSNV	-	1/16
16-2168022-C-T	PKD1	c.971G>A	p.Arg324His	Missense	5/46	-
1-153658297-G-A	NPR1	c.1621G>A	p.Gly541Ser	Missense	9/22	-
13-32911394-G-C	BRCA2	c.2902G>C	p.Gly968Arg	Missense	11/27	-
17-80042508-G-A	FASN	c.4649C>T	p.Ser1550Leu	Missense	27/43	-
1-153658297-G-T	NPR1	c.1621G>T	p.Gly541Cys	Missense	9/22	-
17-37866434-C-A	ERBB2	c.739C>A	p.Pro247Thr	Missense	6/27	-
19-14000196-G-T	C19orf57	c.1473C>A	p.Asp491Glu	Missense	6/8	-
19-39905650-T-C	PLEKHG2	c.128T>C	p.Met43Thr	Missense	3/19	-
2-240913012-G-A	NDUFA10	c.1000-12409C>T	-	IntronicSNV	-	9/9
12-56092638-G-T	ITGA7	c.854C>A	p.Ala285Asp	Missense	6/25	-
19-14000196-G-A	C19orf57	c.1473C>T	p.Asp491Asp	Synonymous	6/8	-
5-173416495-G-T	C5orf47	c.229G>T	p.Val77Phe	Missense	1/5	-
20-1286015-G-A	SNPH	c.802G>A	p.Val268Met	Missense	6/6	-
20-1286015-G-T	SNPH	c.802G>T	p.Val268Leu	Missense	6/6	-
4-100002537-G-C	ADH5	c.323C>G	p.Thr108Ser	Missense	4/9	-
8-39646261-T-A	ADAM2	c.571-2A>T	-	IntronicSNV	-	7/20
1-204950996-G-A	NFASC	c.2318G>A	p.Arg773Gln	Missense	21/30	-
11-62296152-G-A	AHNAK	c.342+6323C>T	-	IntronicSNV	-	4/5
10-116213225-C-T	ABLIM1	c.1279G>A	p.Gly427Ser	Missense	13/23	-
17-7579512-C-G	TP53	c.175G>C	p.Gly59Arg	Missense	4/11	-
11-94322358-G-T	PIWIL4	c.986G>T	p.Arg329Leu	Missense	8/20	-
7-99817878-C-T	PVRIG	c.260C>T	p.Thr87Met	Missense	3/6	-
9-124072992-G-C	GSN	c.535G>C	p.Val179Leu	Missense	4/17	-
19-9068115-G-A	MUC16	c.19331C>T	p.Thr6444Ile	Missense	3/84	-
7-99627504-C-G	ZKSCAN1	c.601C>G	p.Pro201Ala	Missense	4/6	-
19-9068115-G-T	MUC16	c.19331C>A	p.Thr6444Asn	Missense	3/84	-
17-74073386-C-A	GALR2	c.1038C>A	p.Ser346Arg	Missense	2/2	-
17-33324768-A-T	LIG3	c.1835A>T	p.Glu612Val	Missense	12/20	-
12-974498-C-T	WNK1	c.2139+3062C>T	-	IntronicSNV	-	8/27
14-94849061-C-A	SERPINA1	c.514G>T	p.Gly172Trp	Missense	2/5	-
14-94849061-C-T	SERPINA1	c.514G>A	p.Gly172Arg	Missense	2/5	-
2-179441932-G-A	TTN	c.61426C>T	p.Pro20476Ser	Missense	273/312	-
12-124323006-A-G	DNAH10	c.4552A>G	p.Met1518Val	Missense	28/78	-
13-32910540-C-G	BRCA2	c.2048C>G	p.Ser683Cys	Missense	11/27	-
5-131923710-G-A	RAD50	c.980G>A	p.Arg327His	Missense	7/25	-
17-7577111-G-A	TP53	c.827C>T	p.Ala276Val	Missense	8/11	-
5-5186275-G-A	ADAMTS16	c.874G>A	p.Val292Met	Missense	5/23	-
9-117103859-C-A	AKNA	c.4021G>T	p.Ala1341Ser	Missense	21/22	-
13-32907395-A-G	BRCA2	c.1780A>G	p.Ile594Val	Missense	10/27	-
3-184910078-G-A	EHHADH	c.1820C>T	p.Ser607Phe	Missense	7/7	-
20-34092583-A-G	CEP250	c.6386A>G	p.His2129Arg	Missense	30/35	-
7-127224437-C-T	GCC1	c.800G>A	p.Arg267Lys	Missense	1/2	-
15-41337221-G-A	INO80	c.2788C>T	p.Arg930Cys	Missense	24/36	-
2-136362513-T-C	R3HDM1	c.98T>C	p.Ile33Thr	Missense	3/26	-
X-55039960-G-A	ALAS2	c.1559C>T	p.Pro520Leu	Missense	10/11	-
X-78010499-G-A	LPAR4	c.133G>A	p.Val45Ile	Missense	2/2	-
3-98001858-A-C	OR5H2	c.127A>C	p.Thr43Pro	Missense	1/1	-
17-7577119-AC-AA	TP53	c.818_819delGTinsAA	p.Arg273Gln	Missense	8/11	-
17-37868267-CGG-TGT	ERBB2	c.988_990delCGGinsTGT	p.Arg330Cys	Missense	8/27	-
10-50824106-C-T	CHAT	c.287-442C>T	-	IntronicSNV	-	1/14
5-159686752-C-A	CCNJL	c.451G>T	p.Val151Phe	Missense	5/7	-
12-113596869-C-A	CFAP73	c.*375C>A	-	3_prime_UTR_variant	8/8	-
17-72851039-G-A	GRIN2C	c.193C>T	p.Leu65Phe	Missense	2/13	-
16-70298927-G-A	AARS	c.1426C>T	p.Arg476Trp	Missense	11/21	-
19-1122220-A-G	SBNO2	c.1067T>C	p.Ile356Thr	Missense	11/32	-
19-1122220-A-T	SBNO2	c.1067T>A	p.Ile356Asn	Missense	11/32	-
10-13264107-G-C	UCMA	c.413C>G	p.Thr138Ser	Missense	5/5	-
5-159686752-C-T	CCNJL	c.451G>A	p.Val151Ile	Missense	5/7	-
16-1306923-C-T	TPSD1	c.380C>T	p.Ala127Val	Missense	3/5	-
3-48506279-G-A	ATRIP	c.2105G>A	p.Arg702Gln	Missense	12/13	-
16-1306923-C-A	TPSD1	c.380C>A	p.Ala127Glu	Missense	3/5	-
13-32910413-TC-CT	BRCA2	c.1921_1922delTCinsCT	p.Ser641Leu	Missense	11/27	-
22-29446480-G-A	ZNRF3	c.2311G>A	p.Gly771Arg	Missense	8/9	-
17-37865645-A-G	ERBB2	c.514A>G	p.Ile172Val	Missense	4/27	-
18-28612233-G-T	DSC3	c.79C>A	p.Arg27Ser	Missense	2/16	-
18-2747533-T-C	SMCHD1	c.3815T>C	p.Ile1272Thr	Missense	30/48	-
18-34320679-G-A	FHOD3	c.3112G>A	p.Ala1038Thr	Missense	18/25	-
17-5266268-A-G	RABEP1	c.1625A>G	p.Gln542Arg	Missense	10/18	-
5-90016771-G-A	ADGRV1	c.9643G>A	p.Glu3215Lys	Missense	45/90	-
1-152281724-G-A	FLG	c.5638C>T	p.His1880Tyr	Missense	3/3	-
4-153896053-G-A	FHDC1	c.1610G>A	p.Arg537His	Missense	11/11	-
1-158621237-G-A	SPTA1	c.3397C>T	p.Arg1133Trp	Missense	24/52	-
13-32367033-C-G	RXFP2	c.1594C>G	p.Arg532Gly	Missense	16/18	-
1-169438042-T-G	SLC19A2	c.1063A>C	p.Lys355Gln	Missense	4/6	-
7-156752665-G-A	NOM1	c.1429G>A	p.Val477Met	Missense	4/11	-
12-124907067-C-T	NCOR2	c.1363G>A	p.Ala455Thr	Missense	14/49	-
11-124740144-G-A	ROBO3	c.850G>A	p.Asp284Asn	Missense	5/28	-
17-7579497-G-C	TP53	c.190C>G	p.Pro64Ala	Missense	4/11	-
4-36189112-T-C	ARAP2	c.1639A>G	p.Thr547Ala	Missense	8/33	-
19-10335552-G-T	S1PR2	c.30C>A	p.Asn10Lys	Missense	2/2	-
X-140994997-G-A	MAGEC1	c.1807G>A	p.Glu603Lys	Missense	4/4	-
X-140994997-G-C	MAGEC1	c.1807G>C	p.Glu603Gln	Missense	4/4	-
3-126227314-G-A	UROC1	c.356C>T	p.Pro119Leu	Missense	4/20	-
7-156755781-G-A	NOM1	c.1823G>A	p.Arg608His	Missense	6/11	-
3-50391167-C-T	CYB561D2	c.661C>T	p.Gln221*	Nonsense	4/4	-
18-28612233-G-A	DSC3	c.79C>T	p.Arg27Cys	Missense	2/16	-
5-131931472-G-A	RAD50	c.2177G>A	p.Arg726His	Missense	13/25	-
3-126227314-G-C	UROC1	c.356C>G	p.Pro119Arg	Missense	4/20	-
11-116631542-G-C	BUD13	c.1163C>G	p.Ser388Cys	Missense	5/10	-
13-23914588-G-C	SACS	c.3427C>G	p.Gln1143Glu	Missense	10/10	-
13-23914588-G-T	SACS	c.3427C>A	p.Gln1143Lys	Missense	10/10	-
15-48451979-C-T	MYEF2	c.548G>A	p.Arg183His	Missense	6/17	-
5-142500573-A-G	ARHGAP26	c.1559A>G	p.Gln520Arg	Missense	18/23	-
1-226570748-G-A	PARP1	c.1148C>T	p.Ser383Phe	Missense	8/23	-
20-43836960-A-G	SEMG1	c.1022A>G	p.Gln341Arg	Missense	2/3	-
1-226570748-G-T	PARP1	c.1148C>A	p.Ser383Tyr	Missense	8/23	-
11-62600554-G-C	WDR74	c.1028C>G	p.Thr343Arg	Missense	12/12	-
11-62600554-G-A	WDR74	c.1028C>T	p.Thr343Ile	Missense	12/12	-
4-114294537-G-A	ANK2	c.11791G>A	p.Glu3931Lys	Missense	45/46	-
13-32890616-G-A	BRCA2	c.19G>A	p.Glu7Lys	Missense	2/27	-
2-203972703-C-T	NBEAL1	c.1654C>T	p.Arg552*	Nonsense	13/55	-
5-74046462-C-T	GFM2	c.461G>A	p.Arg154Gln	Missense	7/21	-
18-18533600-T-C	ROCK1	c.4000A>G	p.Thr1334Ala	Missense	32/33	-
2-96963419-T-C	SNRNP200	c.1159A>G	p.Met387Val	Missense	10/45	-
1-10529326-A-G	DFFA	c.206T>C	p.Ile69Thr	Missense	2/6	-
5-55250787-G-C	IL6ST	c.1301C>G	p.Pro434Arg	Missense	11/17	-
19-40582086-A-G	ZNF780A	c.263T>C	p.Val88Ala	Missense	6/6	-
11-1017504-G-A	MUC6	c.5297C>T	p.Thr1766Ile	Missense	31/33	-
15-55663993-T-C	CCPG1	c.704A>G	p.Tyr235Cys	Missense	6/8	-
15-55663993-T-A	CCPG1	c.704A>T	p.Tyr235Phe	Missense	6/8	-
1-45480232-T-A	UROD	c.758T>A	p.Leu253Gln	Missense	7/10	-
19-55250976-T-G	KIR2DL3	c.58T>G	p.Trp20Gly	Missense	2/8	-
1-14142973-C-G	PRDM2	c.5088C>G	p.Ile1696Met	Missense	9/10	-
18-7049171-C-T	LAMA1	c.674G>A	p.Arg225His	Missense	5/63	-
9-131267089-C-T	GLE1	c.5C>T	p.Pro2Leu	Missense	1/16	-
10-126683111-C-T	CTBP2	c.707G>A	p.Ser236Asn	Missense	7/11	-
2-128390856-C-T	MYO7B	c.5351C>T	p.Pro1784Leu	Missense	39/47	-
2-128390856-C-A	MYO7B	c.5351C>A	p.Pro1784Gln	Missense	39/47	-
17-37868252-G-A	ERBB2	c.973G>A	p.Glu325Lys	Missense	8/27	-
1-36211107-C-A	CLSPN	c.2911G>T	p.Gly971Cys	Missense	16/25	-
19-39016135-A-T	RYR1	c.10619A>T	p.Tyr3540Phe	Missense	71/106	-
15-55663993-T-G	CCPG1	c.704A>C	p.Tyr235Ser	Missense	6/8	-
11-118849720-C-G	FOXR1	c.190C>G	p.Pro64Ala	Missense	3/6	-
20-9424868-C-A	PLCB4	c.2822C>A	p.Ser941Tyr	Missense	28/36	-
17-46700458-C-T	HOXB9	c.557G>A	p.Arg186Gln	Missense	2/2	-
4-42551048-T-C	ATP8A1	c.1634A>G	p.Asn545Ser	Missense	19/37	-
19-49339590-G-A	HSD17B14	c.79C>T	p.Arg27Cys	Missense	1/9	-
1-53580635-C-T	SLC1A7	c.226G>A	p.Gly76Arg	Missense	3/11	-
1-198718604-G-A	PTPRC	c.2998G>A	p.Asp1000Asn	Missense	28/33	-
6-32032790-G-T	TNXB	c.6649C>A	p.Pro2217Thr	Missense	19/44	-
17-5042763-G-A	USP6	c.1292G>A	p.Gly431Asp	Missense	14/30	-
11-1028379-C-T	MUC6	c.1600G>A	p.Gly534Ser	Missense	14/33	-
17-5042763-G-T	USP6	c.1292G>T	p.Gly431Val	Missense	14/30	-
11-94322358-G-A	PIWIL4	c.986G>A	p.Arg329Gln	Missense	8/20	-
2-186666113-G-A	FSIP2	c.12080G>A	-	missense_variant	17/23	-
8-105235958-G-A	RIMS2	c.3335-21186G>A	-	IntronicSNV	-	19/23
1-41618297-G-A	SCMH1	c.50C>T	p.Pro17Leu	Missense	4/16	-
1-6534643-C-A	PLEKHG5	c.307G>T	p.Val103Leu	Missense	6/21	-
3-184612670-C-T	VPS8	c.1955C>T	p.Ala652Val	Missense	22/47	-
1-6534643-C-T	PLEKHG5	c.307G>A	p.Val103Met	Missense	6/21	-
17-37871567-C-A	ERBB2	c.1177C>A	p.Gln393Lys	Missense	10/27	-
10-126681789-T-G	CTBP2	c.1021A>C	p.Ile341Leu	Missense	9/11	-
11-47663963-G-A	MTCH2	c.55C>T	p.Gln19*	Nonsense	1/13	-
22-38121652-C-T	TRIOBP	c.3089C>T	p.Pro1030Leu	Missense	7/24	-
3-186330934-A-G	AHSG	c.4A>G	p.Lys2Glu	Missense	1/7	-
10-61028353-C-A	FAM13C	c.902G>T	p.Arg301Leu	Missense	8/12	-
10-61028353-C-T	FAM13C	c.902G>A	p.Arg301Gln	Missense	8/12	-
3-193185248-G-T	ATP13A4	c.971C>A	p.Pro324Gln	Missense	10/30	-
6-152576061-C-T	SYNE1	c.19424G>A	p.Arg6475Gln	Missense	104/146	-
11-57296313-G-A	TIMM10	c.150C>T	p.Cys50Cys	Synonymous	3/3	-
3-193185248-G-A	ATP13A4	c.971C>T	p.Pro324Leu	Missense	10/30	-
17-7578408-CCT-CAT	TP53	c.520_522delAGGinsCAT	p.Arg174His	Missense	5/11	-
20-60892518-C-G	LAMA5	c.7394G>C	p.Arg2465Pro	Missense	55/80	-
19-22154829-A-C	ZNF208	c.3007T>G	p.Cys1003Gly	Missense	4/4	-
19-22154829-A-G	ZNF208	c.3007T>C	p.Cys1003Arg	Missense	4/4	-
4-155254540-G-C	DCHS2	c.2820C>G	p.His940Gln	Missense	5/8	-
3-50005373-C-T	RBM6	c.515C>T	p.Pro172Leu	Missense	3/21	-
6-158487551-T-C	SYNJ2	c.1601T>C	p.Met534Thr	Missense	12/27	-
6-158487551-T-A	SYNJ2	c.1601T>A	p.Met534Lys	Missense	12/27	-
4-157891943-T-C	PDGFC	c.113A>G	p.Gln38Arg	Missense	1/6	-
17-45214523-A-C	CDC27	c.1926T>G	p.Asn642Lys	Missense	14/19	-
2-239165676-A-C	PER2	c.1952T>G	p.Leu651Arg	Missense	17/23	-
7-100677873-C-T	MUC17	c.3176C>T	p.Thr1059Met	Missense	3/13	-
7-100677873-C-G	MUC17	c.3176C>G	p.Thr1059Arg	Missense	3/13	-
20-8737719-G-T	PLCB1	c.2550G>T	p.Glu850Asp	Missense	24/32	-
17-41955315-G-A	MPP2	c.1519C>T	p.Arg507Cys	Missense	13/13	-
20-33585405-G-A	MYH7B	c.3835G>A	p.Asp1279Asn	Missense	32/45	-
8-8185582-C-T	PRAG1	c.2716G>A	-	missense_variant	5/6	-
1-47737769-C-T	STIL	c.2362G>A	p.Val788Ile	Missense	13/17	-
17-37884085-G-A	ERBB2	c.3556G>A	p.Ala1186Thr	Missense	27/27	-
8-8185582-C-A	PRAG1	c.2716G>T	-	missense_variant	5/6	-
8-8185582-C-G	PRAG1	c.2716G>C	-	missense_variant	5/6	-
10-24813493-T-C	KIAA1217	c.2698T>C	p.Ser900Pro	Missense	13/21	-
2-120020831-C-A	STEAP3	c.1384C>A	p.Arg462Arg	Synonymous	6/6	-
3-130293232-T-C	COL6A6	c.3410T>C	p.Ile1137Thr	Missense	7/36	-
17-3955341-G-A	ZZEF1	c.5524C>T	p.Arg1842Trp	Missense	35/55	-
1-53569237-G-T	SLC1A7	c.478C>A	p.Arg160Ser	Missense	5/11	-
7-73456961-G-A	ELN	c.250G>A	p.Ala84Thr	Missense	6/33	-
1-53569237-G-A	SLC1A7	c.478C>T	p.Arg160Cys	Missense	5/11	-
7-73456961-G-T	ELN	c.250G>T	p.Ala84Ser	Missense	6/33	-
22-46688704-C-G	TTC38	c.1333C>G	p.Arg445Gly	Missense	14/14	-
1-55067043-A-T	ACOT11	c.986A>T	p.Asp329Val	Missense	9/17	-
19-56028918-C-T	SSC5D	c.3275C>T	p.Pro1092Leu	Missense	14/14	-
9-5765705-G-C	RIC1	c.3044G>C	p.Ser1015Thr	Missense	21/26	-
20-57768655-G-A	ZNF831	c.2581G>A	p.Asp861Asn	Missense	1/5	-
20-57768655-G-C	ZNF831	c.2581G>C	p.Asp861His	Missense	1/5	-
17-30216347-C-T	UTP6	c.500G>A	p.Arg167His	Missense	7/19	-
2-74759825-G-A	HTRA2	c.1195G>A	p.Gly399Ser	Missense	7/8	-
2-172926265-A-G	METAP1D	c.80A>G	p.Tyr27Cys	Missense	2/10	-
11-831554-CG-CGCG	CRACR2B	c.878_879dup	p.Gly294Argfs*52	Frameshift	8/8	-
12-121879022-C-A	KDM2B	c.3299G>T	p.Arg1100Leu	Missense	20/23	-
22-45754606-C-T	SMC1B	c.2932G>A	p.Asp978Asn	Missense	19/25	-
9-35295780-C-T	UNC13B	c.614C>T	p.Thr205Ile	Missense	8/39	-
17-7577537-CCG-TGT	TP53	c.742_744delCGGinsTGT	p.Arg248Cys	Missense	7/11	-
19-10395141-G-A	ICAM1	c.988G>A	p.Val330Met	Missense	5/7	-
9-35295780-C-G	UNC13B	c.614C>G	p.Thr205Arg	Missense	8/39	-
1-27875286-T-A	AHDC1	c.3341A>T	p.Tyr1114Phe	Missense	6/7	-
4-106157698-T-C	TET2	c.2599T>C	p.Tyr867His	Missense	3/3	-
13-32913528-CT-TG	BRCA2	c.5036_5037delCTinsTG	p.Thr1679Met	Missense	11/27	-
18-74701943-T-C	MBP	c.329A>G	p.Glu110Gly	Missense	3/7	-
11-1263137-C-T	MUC5B	c.5027C>T	p.Thr1676Met	Missense	31/49	-
12-53696859-C-T	C12orf10	c.371C>T	p.Pro124Leu	Missense	3/7	-
8-124089460-C-G	TBC1D31	c.187C>G	p.Gln63Glu	Missense	2/22	-
19-49119368-G-A	RPL18	c.389C>T	p.Ser130Phe	Missense	5/7	-
6-111621304-T-A	REV3L	c.9308A>T	p.Asn3103Ile	Missense	33/33	-
11-101832689-A-G	CEP126	c.923A>G	p.His308Arg	Missense	6/11	-
12-6562262-G-A	TAPBPL	c.94G>A	p.Ala32Thr	Missense	2/7	-
15-90992792-G-T	IQGAP1	c.1079G>T	p.Ser360Ile	Missense	11/38	-
7-44150626-C-T	AEBP1	c.1600C>T	p.Arg534Cys	Missense	13/21	-
1-41976300-G-A	HIVEP3	c.7043C>T	p.Pro2348Leu	Missense	9/9	-
19-40366142-C-T	FCGBP	c.14092G>A	p.Ala4698Thr	Missense	30/36	-
11-47303964-A-G	MADD	c.1502A>G	p.Asn501Ser	Missense	9/33	-
1-152759989-G-A	LCE1E	c.214G>A	p.Gly72Arg	Missense	2/2	-
7-47342713-G-A	TNS3	c.3292C>T	p.Leu1098Phe	Missense	22/31	-
12-88500556-C-T	CEP290	c.2713G>A	p.Glu905Lys	Missense	25/54	-
22-38610661-G-A	MAFF	c.271G>A	p.Asp91Asn	Missense	3/3	-
10-70760271-T-C	KIF1BP	c.518T>C	p.Met173Thr	Missense	2/7	-
19-54672316-A-G	TMC4	c.551T>C	p.Met184Thr	Missense	4/15	-
22-19226874-T-C	CLTCL1	c.719A>G	p.Asn240Ser	Missense	5/33	-
12-58350618-C-T	ATP23	c.686C>T	p.Ala229Val	Missense	6/6	-
17-21203961-G-A	MAP2K3	c.270G>A	p.Met90Ile	Missense	4/12	-
2-234113242-C-G	INPP5D	c.3365C>G	-	missense_variant	27/28	-
11-5364175-G-A	OR51B5	c.580C>T	p.Arg194*	Nonsense	5/5	-
17-42477385-T-C	GPATCH8	c.2060A>G	p.His687Arg	Missense	8/8	-
7-48237906-G-C	ABCA13	c.236G>C	p.Gly79Ala	Missense	3/62	-
14-96730863-C-T	BDKRB1	c.844C>T	p.Arg282*	Nonsense	3/3	-
14-96730863-C-G	BDKRB1	c.844C>G	p.Arg282Gly	Missense	3/3	-
1-78958451-A-T	PTGFR	c.23A>T	p.Gln8Leu	Missense	2/3	-
5-131931472-G-T	RAD50	c.2177G>T	p.Arg726Leu	Missense	13/25	-
15-72119273-G-A	MYO9A	c.7295C>T	p.Ser2432Leu	Missense	42/42	-
11-6891726-C-G	OR10A2	c.741C>G	p.Phe247Leu	Missense	1/1	-
2-228173636-A-G	COL4A3	c.4484A>G	p.Gln1495Arg	Missense	49/52	-
1-204944417-G-A	NFASC	c.1577G>A	p.Arg526Gln	Missense	15/30	-
17-7578372-A-T	TP53	c.558T>A	p.Asp186Glu	Missense	5/11	-
12-117977550-C-T	KSR2	c.1661G>A	-	missense_variant	10/20	-
19-39062686-G-A	RYR1	c.13774G>A	p.Asp4592Asn	Missense	95/106	-
22-18178965-G-A	BCL2L13	c.445G>A	p.Gly149Ser	Missense	5/7	-
6-148855036-C-T	SASH1	c.1864C>T	p.Arg622Cys	Missense	15/20	-
5-139747113-A-G	SLC4A9	c.2122A>G	p.Met708Val	Missense	15/22	-
1-20027301-G-T	TMCO4	c.1342C>A	p.Arg448Arg	Synonymous	14/16	-
17-74073094-G-T	GALR2	c.746G>T	p.Trp249Leu	Missense	2/2	-
17-41139295-G-A	RUNDC1	c.521G>A	p.Arg174His	Missense	2/5	-
12-56637583-G-C	ANKRD52	c.2966C>G	p.Ala989Gly	Missense	27/28	-
19-42914668-G-A	LIPE	c.1210C>T	p.Arg404Cys	Missense	2/10	-
17-80203891-C-T	CSNK1D	c.1222G>A	p.Gly408Ser	Missense	9/10	-
12-9908952-C-T	CD69	c.128G>A	p.Cys43Tyr	Missense	2/5	-
8-140744344-G-A	TRAPPC9	c.3451C>T	p.Arg1151Cys	Missense	22/23	-
X-49021370-C-T	MAGIX	c.449C>T	p.Pro150Leu	Missense	4/6	-
17-7579574-T-C	TP53	c.113A>G	p.Gln38Arg	Missense	4/11	-
7-151680202-A-G	GALNTL5	c.500A>G	p.Glu167Gly	Missense	4/9	-
9-134308115-A-G	PRRC2B	c.227A>G	p.Asn76Ser	Missense	2/31	-
1-227216822-C-T	CDC42BPA	c.3620G>A	p.Arg1207Gln	Missense	28/35	-
11-122945462-G-A	CLMP	c.769C>T	p.Arg257*	Nonsense	6/7	-
17-37879812-AG-TT	ERBB2	c.2107_2108delAGinsTT	p.Ser703Phe	Missense	18/27	-
9-86912927-C-T	SLC28A3	c.677G>A	p.Trp226*	Nonsense	8/19	-
13-32907516-CT-AG	BRCA2	c.1901_1902delCTinsAG	p.Ala634Glu	Missense	10/27	-
8-100844615-A-G	VPS13B	c.9424A>G	p.Ser3142Gly	Missense	52/62	-
2-43927245-C-T	PLEKHH2	c.1148C>T	p.Ser383Leu	Missense	8/30	-
19-49564639-G-A	NTF4	c.616C>T	p.Arg206Trp	Missense	2/2	-
11-124747839-G-T	ROBO3	c.2993G>T	p.Gly998Val	Missense	21/28	-
20-1629967-G-A	SIRPG	c.161C>T	p.Thr54Ile	Missense	2/6	-
11-68181342-T-C	LRP5	c.2689T>C	p.Ser897Pro	Missense	12/23	-
12-102158877-C-T	GNPTAB	c.1818G>A	p.Met606Ile	Missense	13/21	-
2-113514767-T-C	CKAP2L	c.181A>G	p.Thr61Ala	Missense	4/9	-
2-232392957-G-T	NMUR1	c.775C>A	p.Arg259Arg	Synonymous	2/3	-
16-2120559-G-T	TSC2	c.1819G>T	p.Ala607Ser	Missense	17/42	-
17-7671351-G-C	DNAH2	c.3809G>C	p.Arg1270Pro	Missense	23/86	-
21-43161252-G-A	RIPK4	c.2101C>T	p.Pro701Ser	Missense	8/8	-
X-15307659-T-A	ASB11	c.559A>T	p.Arg187Trp	Missense	5/7	-
7-4153885-C-T	SDK1	c.3802C>T	p.Arg1268Trp	Missense	25/45	-
4-2941317-G-A	NOP14	c.2255C>T	p.Pro752Leu	Missense	16/19	-
16-72984832-C-G	ZFHX3	c.2752G>C	p.Gly918Arg	Missense	3/10	-
11-66619301-C-A	PC	c.1942G>T	p.Ala648Ser	Missense	16/23	-
16-72984832-C-T	ZFHX3	c.2752G>A	p.Gly918Arg	Missense	3/10	-
1-235922671-T-G	LYST	c.6482A>C	p.Glu2161Ala	Missense	23/53	-
X-48823056-G-C	KCND1	c.1396C>G	p.Leu466Val	Missense	4/6	-
18-74728772-A-G	MBP	c.177+16T>C	-	IntronicSNV	-	1/6
2-169764285-C-A	G6PC2	c.764C>A	p.Pro255His	Missense	5/5	-
17-74073386-C-G	GALR2	c.1038C>G	p.Ser346Arg	Missense	2/2	-
2-232392957-G-A	NMUR1	c.775C>T	p.Arg259Trp	Missense	2/3	-
3-130380745-A-G	COL6A6	c.6095A>G	p.Glu2032Gly	Missense	34/36	-
19-1818839-G-A	REXO1	c.2768C>T	p.Ala923Val	Missense	9/16	-
17-7671351-G-A	DNAH2	c.3809G>A	p.Arg1270His	Missense	23/86	-
9-104187894-A-G	ALDOB	c.640T>C	p.Tyr214His	Missense	7/9	-
1-110882077-G-T	RBM15	c.50G>T	p.Arg17Leu	Missense	1/3	-
17-37868666-T-G	ERBB2	c.1113T>G	p.Phe371Leu	Missense	9/27	-
11-63992434-C-T	TRPT1	c.19G>A	p.Val7Met	Missense	3/7	-
2-238289984-C-G	COL6A3	c.1471G>C	p.Asp491His	Missense	5/44	-
11-63992434-C-A	TRPT1	c.19G>T	p.Val7Leu	Missense	3/7	-
1-146672745-T-G	FMO5	c.1172A>C	p.Gln391Pro	Missense	7/9	-
4-187118692-G-A	CYP4V2	c.610G>A	p.Ala204Thr	Missense	5/11	-
10-102057293-C-T	PKD2L1	c.802G>A	p.Gly268Ser	Missense	5/16	-
11-26463582-C-T	ANO3	c.164C>T	p.Ser55Phe	Missense	2/27	-
17-72931898-T-C	OTOP3	c.2T>C	p.Met1Thr	Missense	1/7	-
11-66468196-C-T	SPTBN2	c.3374G>A	p.Arg1125Gln	Missense	16/37	-
12-55420584-C-G	NEUROD4	c.361C>G	p.Gln121Glu	Missense	2/2	-
2-179479607-G-T	TTN	c.41023C>A	p.Pro13675Thr	Missense	209/312	-
19-5604875-T-C	SAFB2	c.1369A>G	p.Thr457Ala	Missense	10/21	-
2-109421358-A-G	CCDC138	c.749A>G	p.Glu250Gly	Missense	7/15	-
13-32893421-CAA-C	BRCA2	c.275_276delAA	p.Gln92Leufs*8	Frameshift	3/27	-
17-7578251-TTT-T	TP53	c.598_599delAA	p.Asn200Phefs*8	Frameshift	6/11	-
11-56258314-C-T	OR5M8	c.533G>A	p.Cys178Tyr	Missense	1/1	-
13-103701690-G-A	SLC10A2	c.868C>T	p.Pro290Ser	Missense	5/6	-
7-4153885-C-A	SDK1	c.3802C>A	p.Arg1268Arg	Synonymous	25/45	-
8-17510766-C-G	MTUS1	c.3313G>C	p.Glu1105Gln	Missense	12/15	-
12-56090739-C-T	ITGA7	c.1681G>A	p.Val561Met	Missense	12/25	-
13-32899296-C-T	BRCA2	c.400C>T	p.Leu134Phe	Missense	4/27	-
11-121440937-T-C	SORL1	c.3295T>C	p.Phe1099Leu	Missense	23/48	-
2-179482089-C-T	TTN	c.40019G>A	p.Arg13340His	Missense	203/312	-
1-52442588-C-T	RAB3B	c.202G>A	p.Glu68Lys	Missense	2/5	-
20-10393439-C-A	MKKS	c.724G>T	p.Ala242Ser	Missense	3/6	-
19-17088196-C-G	CPAMD8	c.1740G>C	-	missense_variant	15/42	-
12-8990937-C-A	A2ML1	c.861C>A	p.Asp287Glu	Missense	9/36	-
4-48583490-C-T	FRYL	c.2119G>A	p.Val707Ile	Missense	21/64	-
17-37865699-CG-AA	ERBB2	c.568_569delCGinsAA	p.Arg190Lys	Missense	4/27	-
22-43015795-C-T	CYB5R3	c.890G>A	p.Arg297His	Missense	9/9	-
12-8990937-C-T	A2ML1	c.861C>T	p.Asp287Asp	Synonymous	9/36	-
12-6952375-G-T	GNB3	c.241G>T	p.Val81Leu	Missense	5/10	-
2-168110876-C-G	XIRP2	c.*240C>G	-	IntronicSNV	11/11	-
10-126683099-G-A	CTBP2	c.719C>T	p.Ser240Phe	Missense	7/11	-
2-168110876-C-A	XIRP2	c.*240C>A	-	IntronicSNV	11/11	-
6-75831080-C-T	COL12A1	c.7024G>A	p.Val2342Ile	Missense	44/66	-
X-75649236-A-T	MAGEE1	c.913A>T	p.Ser305Cys	Missense	1/1	-
17-45219283-T-C	CDC27	c.1505A>G	p.Tyr502Cys	Missense	12/19	-
9-78790143-G-A	PCSK5	c.1900+98G>A	-	IntronicSNV	-	14/36
2-75914985-A-T	GCFC2	c.1658T>A	p.Ile553Asn	Missense	11/17	-
11-17631453-C-T	OTOG	c.4642C>T	p.Leu1548Phe	Missense	35/55	-
17-5389469-T-G	DERL2	c.13A>C	p.Ser5Arg	Missense	1/7	-
17-5389469-T-C	DERL2	c.13A>G	p.Ser5Gly	Missense	1/7	-
12-53700853-G-A	C12orf10	c.1051G>A	p.Gly351Ser	Missense	7/7	-
X-49021639-C-T	MAGIX	c.619C>T	p.Arg207Trp	Missense	5/6	-
18-33795564-C-T	MOCOS	c.1421C>T	p.Thr474Met	Missense	8/15	-
18-33795564-C-A	MOCOS	c.1421C>A	p.Thr474Lys	Missense	8/15	-
1-6635259-C-G	TAS1R1	c.1067C>G	p.Ser356Cys	Missense	3/6	-
11-2946317-C-T	SLC22A18	c.1165C>T	p.Arg389Cys	Missense	11/11	-
11-118531367-A-T	TREH	c.983T>A	p.Ile328Asn	Missense	10/16	-
13-32913207-C-T	BRCA2	c.4715C>T	p.Ala1572Val	Missense	11/27	-
8-6389998-T-G	ANGPT2	c.299A>C	p.Tyr100Ser	Missense	2/9	-
8-6389998-T-A	ANGPT2	c.299A>T	p.Tyr100Phe	Missense	2/9	-
7-2317934-G-A	SNX8	c.101C>T	p.Pro34Leu	Missense	2/11	-
7-2317934-G-C	SNX8	c.101C>G	p.Pro34Arg	Missense	2/11	-
15-48559812-G-A	SLC12A1	c.2209G>A	p.Ala737Thr	Missense	18/27	-
16-68855966-G-A	CDH1	c.1774G>A	p.Ala592Thr	Missense	12/16	-
8-141672767-T-A	PTK2	c.3012+2249A>T	-	IntronicSNV	-	31/31
8-141672767-T-C	PTK2	c.3012+2249A>G	-	IntronicSNV	-	31/31
7-103197603-G-A	RELN	c.5618C>T	p.Thr1873Ile	Missense	38/65	-
20-62839672-C-G	MYT1	c.1123C>G	p.Arg375Gly	Missense	7/23	-
20-62839672-C-T	MYT1	c.1123C>T	p.Arg375Trp	Missense	7/23	-
12-51739625-C-A	CELA1	c.53G>T	p.Arg18Leu	Missense	2/8	-
2-220431630-C-T	OBSL1	c.2056G>A	p.Val686Ile	Missense	5/9	-
14-105609400-G-A	JAG2	c.3349C>T	p.Arg1117Trp	Missense	26/26	-
11-118531367-A-G	TREH	c.983T>C	p.Ile328Thr	Missense	10/16	-
11-63884416-G-A	FLRT1	c.677G>A	p.Arg226His	Missense	2/2	-
11-63884416-G-T	FLRT1	c.677G>T	p.Arg226Leu	Missense	2/2	-
16-68855966-G-T	CDH1	c.1774G>T	p.Ala592Ser	Missense	12/16	-
1-152190873-G-A	HRNR	c.3232C>T	p.Gln1078*	Nonsense	3/3	-
1-216465694-G-C	USH2A	c.1663C>G	p.Leu555Val	Missense	10/21	-
12-51739625-C-T	CELA1	c.53G>A	p.Arg18His	Missense	2/8	-
19-1923155-C-T	SCAMP4	c.482C>T	p.Ser161Leu	Missense	6/7	-
17-37864647-G-A	ERBB2	c.299G>A	p.Arg100Gln	Missense	3/27	-
12-52845481-G-C	KRT6B	c.382C>G	p.Pro128Ala	Missense	1/9	-
1-55518412-C-A	PCSK9	c.747C>A	p.Ser249Arg	Missense	5/12	-
20-46279918-C-T	NCOA3	c.3832C>T	p.Pro1278Ser	Missense	20/23	-
12-111291255-C-T	CCDC63	c.56C>T	p.Ser19Leu	Missense	3/12	-
12-111291255-C-A	CCDC63	c.56C>A	p.Ser19*	Nonsense	3/12	-
16-72984832-C-A	ZFHX3	c.2752G>T	p.Gly918Trp	Missense	3/10	-
5-79030623-C-T	CMYA5	c.6035C>T	p.Ser2012Phe	Missense	2/13	-
1-175325592-C-T	TNR	c.2981G>A	p.Gly994Glu	Missense	16/23	-
20-44639599-C-A	MMP9	c.559C>A	p.Leu187Ile	Missense	4/13	-
5-79030623-C-G	CMYA5	c.6035C>G	p.Ser2012Cys	Missense	2/13	-
1-175375513-G-A	TNR	c.338C>T	p.Thr113Ile	Missense	3/23	-
12-88519133-C-T	CEP290	c.1079G>A	p.Arg360Gln	Missense	13/54	-
22-42910722-G-A	RRP7A	c.524C>T	p.Thr175Met	Missense	5/7	-
19-18120757-G-A	ARRDC2	c.758G>A	p.Arg253Gln	Missense	5/8	-
17-37864593-G-T	ERBB2	c.245G>T	p.Gly82Val	Missense	3/27	-
6-32049177-C-T	TNXB	c.4010G>A	p.Arg1337His	Missense	10/44	-
4-77230712-G-C	FAM47E-STBD1	c.*386G>C	-	3-UTRSNV	7/7	-
5-167653121-G-T	TENM2	c.5110G>T	p.Val1704Leu	Missense	25/30	-
17-18152710-C-G	FLII	c.1789G>C	p.Asp597His	Missense	15/30	-
3-14199940-C-A	XPC	c.1443G>T	p.Lys481Asn	Missense	9/16	-
15-41148251-G-A	SPINT1	c.1279G>A	p.Gly427Ser	Missense	9/11	-
19-17831206-G-A	MAP1S	c.119-539G>A	-	IntronicSNV	-	1/6
9-77377724-C-T	TRPM6	c.3863G>A	p.Gly1288Glu	Missense	26/39	-
15-78893923-A-G	CHRNA3	c.1061T>C	p.Met354Thr	Missense	5/6	-
6-32049177-C-G	TNXB	c.4010G>C	p.Arg1337Pro	Missense	10/44	-
6-32049177-C-A	TNXB	c.4010G>T	p.Arg1337Leu	Missense	10/44	-
3-57893682-G-A	SLMAP	c.1471G>A	p.Glu491Lys	Missense	15/21	-
20-34067860-C-T	CEP250	c.2476C>T	p.Arg826Trp	Missense	20/35	-
1-152193195-G-A	HRNR	c.910C>T	p.Arg304Cys	Missense	3/3	-
17-76133356-G-C	TMC8	c.1168G>C	p.Val390Leu	Missense	10/16	-
17-77710990-C-T	ENPP7	c.1177C>T	p.Arg393Trp	Missense	4/6	-
X-19398315-C-T	MAP3K15	c.2512G>A	p.Gly838Ser	Missense	19/29	-
19-49409101-G-A	NUCB1	c.335G>A	p.Arg112Gln	Missense	4/13	-
17-5066289-C-T	USP6	c.3026C>T	p.Ser1009Phe	Missense	25/30	-
17-37864772-C-T	ERBB2	c.424C>T	p.Leu142Phe	Missense	3/27	-
11-116636108-G-T	BUD13	c.292C>A	p.Arg98Ser	Missense	3/10	-
15-89382103-G-T	ACAN	c.280G>T	p.Val94Leu	Missense	3/16	-
15-89382103-G-A	ACAN	c.280G>A	p.Val94Met	Missense	3/16	-
16-9857547-C-A	GRIN2A	c.3854G>T	p.Arg1285Met	Missense	14/14	-
5-140221071-G-T	PCDHA1	c.2394+52802G>T	-	IntronicSNV	-	1/3
16-9857547-C-T	GRIN2A	c.3854G>A	p.Arg1285Lys	Missense	14/14	-
22-46760125-A-G	CELSR1	c.8803T>C	p.Tyr2935His	Missense	34/35	-
3-183818224-G-A	HTR3E	c.64G>A	p.Glu22Lys	Missense	1/8	-
2-203995185-G-T	NBEAL1	c.3463G>T	p.Glu1155*	Nonsense	24/55	-
13-32900675-G-C	BRCA2	c.556G>C	p.Ala186Pro	Missense	7/27	-
17-47246239-G-A	B4GALNT2	c.1472G>A	p.Arg491His	Missense	10/11	-
13-32907450-A-T	BRCA2	c.1835A>T	p.Glu612Val	Missense	10/27	-
2-46707851-G-A	TMEM247	c.425G>A	p.Arg142Gln	Missense	2/3	-
1-197091124-C-T	ASPM	c.3791G>A	p.Arg1264His	Missense	16/28	-
19-35741258-C-T	LSR	c.294C>T	p.Tyr98Tyr	Synonymous	2/9	-
4-107847026-C-A	DKK2	c.303G>T	p.Met101Ile	Missense	2/4	-
2-33572566-G-A	LTBP1	c.3989G>A	p.Arg1330Gln	Missense	26/34	-
3-52436832-C-T	BAP1	c.1946G>A	p.Cys649Tyr	Missense	15/17	-
4-6862665-G-T	KIAA0232	c.556G>T	p.Val186Phe	Missense	7/10	-
10-7290605-C-T	SFMBT2	c.877G>A	p.Ala293Thr	Missense	8/21	-
7-151848538-G-C	KMT2C	c.12655C>G	p.Leu4219Val	Missense	50/59	-
2-179600475-C-T	TTN	c.10966G>A	p.Ala3656Thr	Missense	47/312	-
7-893208-G-A	SUN1	c.967G>A	p.Gly323Arg	Missense	9/18	-
3-52436832-C-G	BAP1	c.1946G>C	p.Cys649Ser	Missense	15/17	-
11-6891809-T-C	OR10A2	c.824T>C	p.Ile275Thr	Missense	1/1	-
12-6859407-T-C	MLF2	c.335A>G	p.Asn112Ser	Missense	6/9	-
12-117669852-G-A	NOS1	c.3320C>T	p.Thr1107Met	Missense	22/29	-
15-33954490-T-C	RYR3	c.4759T>C	p.Ser1587Pro	Missense	35/104	-
15-33954490-T-A	RYR3	c.4759T>A	p.Ser1587Thr	Missense	35/104	-
7-4801973-G-C	FOXK1	c.2080G>C	p.Ala694Pro	Missense	9/9	-
7-4801973-G-A	FOXK1	c.2080G>A	p.Ala694Thr	Missense	9/9	-
12-123339487-C-G	HIP1R	c.754C>G	p.Arg252Gly	Missense	9/32	-
8-17882958-C-T	PCM1	c.5930C>T	p.Ser1977Leu	Missense	37/39	-
X-48923285-C-T	CCDC120	c.865C>T	p.Arg289Cys	Missense	9/10	-
9-78790138-A-G	PCSK5	c.1900+93A>G	-	IntronicSNV	-	14/36
1-41474343-G-A	CTPS1	c.1406G>A	p.Gly469Glu	Missense	15/19	-
19-13993764-G-A	C19orf57	c.1765C>T	p.Arg589Trp	Missense	8/8	-
18-72234625-C-T	CNDP1	c.713C>T	p.Ala238Val	Missense	6/12	-
2-233990592-A-C	INPP5D	c.487A>C	p.Thr163Pro	Missense	4/28	-
18-72234625-C-A	CNDP1	c.713C>A	p.Ala238Glu	Missense	6/12	-
2-141298635-C-T	LRP1B	c.7420G>A	p.Gly2474Ser	Missense	45/91	-
17-27896342-C-G	TP53I13	c.148C>G	p.Pro50Ala	Missense	3/7	-
19-13059563-G-A	RAD23A	c.536G>A	p.Arg179Gln	Missense	5/9	-
6-17602826-G-T	FAM8A1	c.718G>T	p.Glu240*	Nonsense	2/5	-
7-100205706-G-C	PCOLCE	c.1330G>C	p.Ala444Pro	Missense	9/9	-
7-107626756-G-C	LAMB1	c.476C>G	p.Thr159Ser	Missense	6/34	-
17-7579713-T-C	TP53	c.83A>G	p.Glu28Gly	Missense	3/11	-
8-105080802-G-A	RIMS2	c.3334+53959G>A	-	IntronicSNV	-	19/23
22-39884847-G-C	MGAT3	c.1495G>C	p.Asp499His	Missense	2/2	-
1-26189517-C-T	PAQR7	c.814G>A	p.Gly272Arg	Missense	2/2	-
14-67390981-A-G	GPHN	c.800A>G	p.Asn267Ser	Missense	8/23	-
17-72851210-C-T	GRIN2C	c.22G>A	p.Ala8Thr	Missense	2/13	-
6-170070759-G-A	WDR27	c.362C>T	p.Ser121Leu	Missense	4/26	-
8-98731338-G-A	MTDH	c.1442G>A	p.Arg481His	Missense	10/12	-
3-179689390-G-A	PEX5L	c.85C>T	p.Gln29*	Nonsense	2/15	-
3-47307226-A-T	KIF9	c.910T>A	p.Ser304Thr	Missense	9/22	-
7-44098033-C-T	DBNL	c.710C>T	p.Thr237Met	Missense	8/13	-
12-130648429-G-A	FZD10	c.942G>A	p.Leu314Leu	Synonymous	1/1	-
1-185704020-G-A	HMCN1	c.109G>A	p.Glu37Lys	Missense	1/107	-
5-89979871-G-A	ADGRV1	c.6133G>A	p.Gly2045Arg	Missense	28/90	-
19-42880839-G-C	MEGF8	c.8249G>C	p.Gly2750Ala	Missense	41/41	-
2-219562237-A-G	STK36	c.2750A>G	p.Gln917Arg	Missense	24/27	-
4-88235068-G-C	HSD17B13	c.602C>G	p.Ser201*	Nonsense	5/7	-
4-77230712-G-A	FAM47E-STBD1	c.*386G>A	-	3-UTRSNV	7/7	-
19-42813971-C-T	PRR19	c.235C>T	p.His79Tyr	Missense	2/3	-
16-15163979-G-T	RRN3	c.1392C>A	p.Phe464Leu	Missense	14/18	-
14-21549035-C-T	ARHGEF40	c.358C>T	p.Arg120Cys	Missense	13/24	-
1-887938-G-A	NOC2L	c.1045C>T	p.Pro349Ser	Missense	10/19	-
13-32912081-A-G	BRCA2	c.3589A>G	p.Lys1197Glu	Missense	11/27	-
14-21549035-C-A	ARHGEF40	c.358C>A	p.Arg120Ser	Missense	13/24	-
X-117805080-C-T	DOCK11	c.5171C>T	p.Pro1724Leu	Missense	46/53	-
7-151902197-C-G	KMT2C	c.3955G>C	p.Asp1319His	Missense	25/59	-
16-67338357-A-G	KCTD19	c.418T>C	p.Ser140Pro	Missense	3/16	-
10-103343423-G-A	POLL	c.907C>T	p.Pro303Ser	Missense	6/9	-
19-1061830-G-A	ABCA7	c.5513G>A	p.Arg1838His	Missense	41/47	-
16-67338357-A-T	KCTD19	c.418T>A	p.Ser140Thr	Missense	3/16	-
10-103343423-G-T	POLL	c.907C>A	p.Pro303Thr	Missense	6/9	-
2-204000802-G-C	NBEAL1	c.4129G>C	p.Gly1377Arg	Missense	27/55	-
19-41515255-C-A	CYP2B6	c.777C>A	p.Ser259Arg	Missense	5/9	-
11-118133248-T-A	MPZL2	c.341A>T	p.Gln114Leu	Missense	3/6	-
19-1061830-G-T	ABCA7	c.5513G>T	p.Arg1838Leu	Missense	41/47	-
16-67237476-C-G	ELMO3	c.1940C>G	-	missense_variant	19/20	-
20-60886089-G-C	LAMA5	c.10150C>G	p.Arg3384Gly	Missense	74/80	-
20-60886089-G-A	LAMA5	c.10150C>T	p.Arg3384Cys	Missense	74/80	-
13-32905149-AGA-TGG	BRCA2	c.775_777delAGAinsTGG	p.Arg259Trp	Missense	9/27	-
15-78911138-T-C	CHRNA3	c.202A>G	p.Met68Val	Missense	2/6	-
3-48677452-C-T	CELSR3	c.9566G>A	p.Arg3189Gln	Missense	34/35	-
12-130647809-G-T	FZD10	c.322G>T	p.Val108Phe	Missense	1/1	-
19-22154829-A-T	ZNF208	c.3007T>A	p.Cys1003Ser	Missense	4/4	-
12-130647809-G-A	FZD10	c.322G>A	p.Val108Ile	Missense	1/1	-
13-32911824-T-C	BRCA2	c.3332T>C	p.Ile1111Thr	Missense	11/27	-
10-24762833-G-A	KIAA1217	c.1523G>A	p.Arg508His	Missense	6/21	-
2-97531651-G-A	SEMA4C	c.274C>T	p.Pro92Ser	Missense	4/15	-
2-96933097-C-T	CIAO1	c.178C>T	p.His60Tyr	Missense	2/7	-
10-24762833-G-T	KIAA1217	c.1523G>T	p.Arg508Leu	Missense	6/21	-
15-66621382-G-A	DIS3L	c.2027G>A	p.Arg676His	Missense	13/17	-
1-43787367-G-A	TIE1	c.3326G>A	p.Arg1109His	Missense	22/23	-
7-6049010-G-C	AIMP2	c.16G>C	p.Val6Leu	Missense	1/4	-
6-32726794-C-G	HLA-DQB2	c.479G>C	p.Arg160Pro	Missense	3/5	-
6-32726794-C-T	HLA-DQB2	c.479G>A	p.Arg160Gln	Missense	3/5	-
2-68613814-A-C	PLEK	c.653A>C	p.Tyr218Ser	Missense	5/9	-
6-33373341-C-T	KIFC1	c.1469C>T	p.Ala490Val	Missense	7/11	-
5-96112237-A-G	ERAP1	c.2689T>C	p.Ser897Pro	Missense	19/20	-
17-7667554-C-T	DNAH2	c.3299C>T	p.Ala1100Val	Missense	20/86	-
22-38877244-G-C	KDELR3	c.379G>C	p.Glu127Gln	Missense	4/5	-
3-48677191-G-A	CELSR3	c.9827C>T	p.Pro3276Leu	Missense	34/35	-
16-68387410-C-T	PRMT7	c.1591C>T	p.Arg531Trp	Missense	16/19	-
19-19646458-A-G	YJEFN3	c.664A>G	p.Ile222Val	Missense	6/7	-
6-31134122-A-C	POU5F1	c.406-298T>G	-	IntronicSNV	-	1/4
6-31134122-A-G	POU5F1	c.406-298T>C	-	IntronicSNV	-	1/4
3-52550173-G-A	STAB1	c.4063G>A	p.Glu1355Lys	Missense	38/69	-
18-2925359-C-T	LPIN2	c.1801G>A	p.Glu601Lys	Missense	14/20	-
12-88454728-A-G	CEP290	c.6401T>C	p.Ile2134Thr	Missense	47/54	-
2-128389835-G-A	MYO7B	c.5186G>A	p.Arg1729Gln	Missense	38/47	-
1-167038251-G-A	GPA33	c.323C>T	p.Thr108Ile	Missense	3/7	-
3-48677389-C-T	CELSR3	c.9629G>A	p.Arg3210Gln	Missense	34/35	-
17-7579532-TTGTTCAATAT-T	TP53	c.148_157delATTGAACAAT	p.Ile50Glyfs*70	Frameshift	4/11	-
13-32900238-T-TT	BRCA2	c.426dupT	-	SpliceAcceptorInsertion	5/27	-
17-7578269-G-A	TP53	c.580C>T	p.Leu194Phe	Missense	6/11	-
9-414863-A-G	DOCK8	c.3612A>G	p.Lys1204Lys	Synonymous	29/48	-
2-39239286-G-T	SOS1	c.2371C>A	p.Leu791Ile	Missense	14/23	-
5-72865362-G-T	UTP15	c.409G>T	p.Val137Leu	Missense	5/13	-
3-48677191-G-T	CELSR3	c.9827C>A	p.Pro3276His	Missense	34/35	-
7-4051764-A-C	SDK1	c.2317A>C	p.Lys773Gln	Missense	16/45	-
2-198949074-C-T	PLCL1	c.833C>T	p.Ala278Val	Missense	2/6	-
6-148855036-C-A	SASH1	c.1864C>A	p.Arg622Ser	Missense	15/20	-
15-33022994-C-G	GREM1	c.103C>G	p.Pro35Ala	Missense	2/2	-
17-37864626-A-T	ERBB2	c.278A>T	p.Gln93Leu	Missense	3/27	-
17-45234331-T-G	CDC27	c.790A>C	p.Thr264Pro	Missense	7/19	-
12-56092638-G-C	ITGA7	c.854C>G	p.Ala285Gly	Missense	6/25	-
12-56092638-G-A	ITGA7	c.854C>T	p.Ala285Val	Missense	6/25	-
3-195300740-C-T	APOD	c.226G>A	p.Val76Met	Missense	3/5	-
3-50368118-C-T	RASSF1	c.464G>A	p.Arg155His	Missense	5/5	-
2-152471058-A-G	NEB	c.10604T>C	p.Ile3535Thr	Missense	74/150	-
22-24709420-C-T	SPECC1L	c.293C>T	p.Ser98Phe	Missense	4/17	-
2-68613814-A-G	PLEK	c.653A>G	p.Tyr218Cys	Missense	5/9	-
6-17764896-G-C	KIF13A	c.4758C>G	p.Asp1586Glu	Missense	38/38	-
4-134072821-G-A	PCDH10	c.1526G>A	p.Gly509Asp	Missense	1/5	-
2-116066882-T-C	DPP10	c.128T>C	p.Leu43Ser	Missense	2/26	-
17-41143549-C-G	RUNDC1	c.1658C>G	p.Ser553Cys	Missense	5/5	-
1-41283849-T-C	KCNQ4	c.419T>C	p.Ile140Thr	Missense	3/14	-
3-129289978-G-T	PLXND1	c.3505C>A	p.Arg1169Ser	Missense	18/36	-
1-45500083-C-T	ZSWIM5	c.2350G>A	p.Val784Met	Missense	11/14	-
3-129289978-G-A	PLXND1	c.3505C>T	p.Arg1169Cys	Missense	18/36	-
16-75276547-T-C	BCAR1	c.454A>G	p.Thr152Ala	Missense	2/7	-
17-5066289-C-G	USP6	c.3026C>G	p.Ser1009Cys	Missense	25/30	-
17-75398327-C-T	SEPT9	c.209C>T	p.Ala70Val	Missense	2/11	-
1-44422884-C-T	IPO13	c.1289C>T	p.Thr430Met	Missense	6/20	-
17-76133356-G-A	TMC8	c.1168G>A	p.Val390Ile	Missense	10/16	-
22-44368856-C-T	SAMM50	c.535C>T	p.Pro179Ser	Missense	6/15	-
1-27875286-T-C	AHDC1	c.3341A>G	p.Tyr1114Cys	Missense	6/7	-
22-44368856-C-G	SAMM50	c.535C>G	p.Pro179Ala	Missense	6/15	-
15-45393430-G-A	DUOX2	c.2894C>T	p.Ser965Leu	Missense	22/34	-
10-16967417-T-C	CUBN	c.6469A>G	p.Asn2157Asp	Missense	43/67	-
18-65179687-T-C	DSEL	c.2189A>G	p.Asp730Gly	Missense	2/2	-
5-170338070-T-C	RANBP17	c.692T>C	p.Ile231Thr	Missense	7/28	-
X-140993801-G-T	MAGEC1	c.611G>T	p.Arg204Leu	Missense	4/4	-
12-6566659-C-T	TAPBPL	c.653C>T	p.Pro218Leu	Missense	4/7	-
9-414863-A-T	DOCK8	c.3612A>T	p.Lys1204Asn	Missense	29/48	-
1-6528150-T-G	PLEKHG5	c.2746A>C	p.Thr916Pro	Missense	20/21	-
19-12386869-A-C	ZNF44	c.32T>G	p.Val11Gly	Missense	2/4	-
2-170030537-G-C	LRP2	c.10906C>G	p.Arg3636Gly	Missense	56/79	-
8-145737064-C-G	RECQL4	c.3502G>C	-	missense_variant,splice_region_variant	21/22	-
12-123339487-C-T	HIP1R	c.754C>T	p.Arg252Trp	Missense	9/32	-
9-414863-A-C	DOCK8	c.3612A>C	p.Lys1204Asn	Missense	29/48	-
2-228884530-G-A	SPHKAP	c.1040C>T	p.Ser347Phe	Missense	7/11	-
5-150922130-T-C	FAT2	c.8558A>G	p.Glu2853Gly	Missense	9/23	-
22-44360335-G-A	SAMM50	c.136G>A	p.Val46Ile	Missense	3/15	-
9-121929828-C-T	BRINP1	c.1820G>A	p.Arg607Gln	Missense	8/8	-
2-176965359-C-T	HOXD12	c.684C>T	p.Asn228Asn	Synonymous	2/2	-
19-12386869-A-T	ZNF44	c.32T>A	p.Val11Glu	Missense	2/4	-
7-154263965-T-G	DPP6	c.591T>G	p.Asp197Glu	Missense	5/26	-
19-50905151-G-A	POLD1	c.433G>A	p.Ala145Thr	Missense	4/27	-
13-32906837-A-G	BRCA2	c.1222A>G	p.Met408Val	Missense	10/27	-
3-50326292-C-T	IFRD2	c.1154G>A	p.Arg385His	Missense	9/12	-
13-41767589-G-A	KBTBD7	c.805C>T	p.His269Tyr	Missense	1/1	-
3-51673633-G-A	RAD54L2	c.2059G>A	p.Val687Ile	Missense	13/23	-
13-32906945-A-G	BRCA2	c.1330A>G	p.Asn444Asp	Missense	10/27	-
8-145737064-C-T	RECQL4	c.3502G>A	-	missense_variant,splice_region_variant	21/22	-
17-76118721-G-C	TMC6	c.1192C>G	p.Arg398Gly	Missense	10/20	-
11-62288492-A-C	AHNAK	c.342+13983T>G	-	IntronicSNV	-	4/5
17-7577061-C-CGC	TP53	c.877_878insCG	p.Gly293Alafs*53	Frameshift	8/11	-
1-183212401-C-T	LAMC2	c.3448C>T	p.Arg1150Cys	Missense	23/23	-
4-77053804-G-A	NUP54	c.635C>T	p.Thr212Met	Missense	5/11	-
17-76471536-C-T	DNAH17	c.8335G>A	p.Ala2779Thr	Missense	54/81	-
9-140069828-C-T	ANAPC2	c.2117G>A	p.Arg706His	Missense	12/13	-
12-63543693-G-A	AVPR1A	c.924C>T	p.Phe308Phe	Synonymous	1/2	-
5-38486008-T-C	LIFR	c.2410A>G	p.Lys804Glu	Missense	17/20	-
12-63543693-G-T	AVPR1A	c.924C>A	p.Phe308Leu	Missense	1/2	-
17-37863282-G-T	ERBB2	c.113G>T	p.Ser38Ile	Missense	2/27	-
1-153659131-G-A	NPR1	c.1768G>A	p.Val590Met	Missense	11/22	-
17-37863362-CTG-TTT	ERBB2	c.193_195delCTGinsTTT	p.Leu65Phe	Missense	2/27	-
5-150502492-A-C	ANXA6	c.1219T>G	p.Ser407Ala	Missense	16/26	-
11-55761734-T-A	OR5F1	c.368A>T	p.Tyr123Phe	Missense	1/1	-
9-101830877-G-A	COL15A1	c.3878G>A	p.Gly1293Asp	Missense	41/42	-
19-53268990-C-G	ZNF600	c.2019G>C	p.Lys673Asn	Missense	3/3	-
14-50122494-G-T	POLE2	c.823C>A	p.Leu275Ile	Missense	11/19	-
7-47342790-G-A	TNS3	c.3215C>T	p.Thr1072Met	Missense	22/31	-