Publications:

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Molecular Mechanisms in Autoimmune Thyroid Disease.

Cells

Vargas-Uricoechea, Hernando H

Publication Date: 2023-03-16

Variant appearance in text: PTPN22: R263Q

PubMed Link: 36980259

Variant Present in the following documents:

• Main text
• cells-12-00918.pdf

View BVdb publication page

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Analysis of PTPN22 -1123 G>C, +788 G>A and +1858 C>T Polymorphisms in Patients with Primary Sjögren's Syndrome.

Diagnostics (Basel, Switzerland)

Menchaca-Tapia, Paula Annahi PA; Marín-Rosales, Miguel M; Salazar-Camarena, Diana Celeste DC; Cruz, Alvaro A; Oregon-Romero, Edith E; Tapia-Llanos, Raziel R; Muñoz-Valle, José Francisco JF; Palafox-Sánchez, Claudia Azucena CA

Publication Date: 2023-02-27

Variant appearance in text: PTPN22: R263Q; rs33996649

PubMed Link: 36900045

Variant Present in the following documents:

• Main text
• diagnostics-13-00899.pdf

View BVdb publication page

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Genetic Polymorphism of PTPN22 in Autoimmune Diseases: A Comprehensive Review.

Medicina (Kaunas, Lithuania)

Tizaoui, Kalthoum K; Shin, Jae Il JI; Jeong, Gwang Hun GH; Yang, Jae Won JW; Park, Seoyeon S; Kim, Ji Hong JH; Hwang, Soo Young SY; Park, Se Jin SJ; Koyanagi, Ai A; Smith, Lee L

Publication Date: 2022-08-02

Variant appearance in text: PTPN22: R263Q; rs33996649

PubMed Link: 36013501

Variant Present in the following documents:

• Main text
• medicina-58-01034.pdf

View BVdb publication page

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Genomic, transcriptomic, and metabolomic profiles of hiPSC-derived dopamine neurons from clinically discordant brothers with identical PRKN deletions.

Npj Parkinson'S Disease

Cukier, Holly N HN; Kim, Hyunjin H; Griswold, Anthony J AJ; Codreanu, Simona G SG; Prince, Lisa M LM; Sherrod, Stacy D SD; McLean, John A JA; Dykxhoorn, Derek M DM; Ess, Kevin C KC; Hedera, Peter P; Bowman, Aaron B AB; Neely, M Diana MD

Publication Date: 2022-06-29

Variant appearance in text: rs33996649

PubMed Link: 35768426

Variant Present in the following documents:

• 41531_2022_346_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Single-nucleotide polymorphisms as important risk factors of diabetes among Middle East population.

Human Genomics

Akhlaghipour, Iman I; Bina, Amir Reza AR; Mogharrabi, Mohammad Reza MR; Fanoodi, Ali A; Ebrahimian, Amir Reza AR; Khojasteh Kaffash, Soroush S; Babazadeh Baghan, Atefeh A; Khorashadizadeh, Mohammad Erfan ME; Taghehchian, Negin N; Moghbeli, Meysam M

Publication Date: 2022-04-02

Variant appearance in text: rs33996649

PubMed Link: 35366956

Variant Present in the following documents:

• Main text

View BVdb publication page

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Characterization of Rheumatoid Arthritis Risk-Associated SNPs and Identification of Novel Therapeutic Sites Using an In-Silico Approach.

Biology

Akhtar, Mehran M; Ali, Yasir Y; Islam, Zia-Ul ZU; Arshad, Maria M; Rauf, Mamoona M; Ali, Muhammad M; Maodaa, Saleh N SN; Al-Farraj, Saleh A SA; El-Serehy, Hamed A HA; Jalil, Fazal F

Publication Date: 2021-06-04

Variant appearance in text: PTPN22: R263Q; rs33996649

PubMed Link: 34199962

Variant Present in the following documents:

• Main text
• biology-10-00501.pdf

View BVdb publication page

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A novel CD209 polymorphism is associated with rheumatoid arthritis patients in Taiwan.

Journal Of Clinical Laboratory Analysis

Chan, Hua-Chen HC; Wang, Shu-Chen SC; Lin, Chia-Hui CH; Lin, Yuan-Zhao YZ; Li, Ruei-Nian RN; Yen, Jeng-Hsien JH

Publication Date: 2021-05

Variant appearance in text: PTPN22: R263Q

PubMed Link: 33792986

Variant Present in the following documents:

• JCLA-35-e23751.pdf

View BVdb publication page

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Influence of PTPN22 Allotypes on Innate and Adaptive Immune Function in Health and Disease.

Frontiers In Immunology

Armitage, Lucas H LH; Wallet, Mark A MA; Mathews, Clayton E CE

Publication Date: 2021

Variant appearance in text: PTPN22: R263Q; rs33996649

PubMed Link: 33717184

Variant Present in the following documents:

• Main text

View BVdb publication page

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Association of PTPN22-C1858T Polymorphism With Susceptibility to Mycobacterium tuberculosis and Mycobacterium leprae Infection: A Meta-Analysis.

Frontiers In Immunology

Li, Shuping S; Wang, Xiaohua X; Zhao, Yuming Y; Yang, Juan J; Cui, Tianjiao T; Zhao, Zhizhuang Joe ZJ; Chen, Yun Y; Zheng, Zhihua Z

Publication Date: 2021

Variant appearance in text: rs33996649

PubMed Link: 33717071

Variant Present in the following documents:

• Main text
• fimmu-12-592841.pdf

View BVdb publication page

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Modulation of TCR Signaling by Tyrosine Phosphatases: From Autoimmunity to Immunotherapy.

Frontiers In Cell And Developmental Biology

Castro-Sanchez, Patricia P; Teagle, Alexandra R AR; Prade, Sonja S; Zamoyska, Rose R

Publication Date: 2020

Variant appearance in text: PTPN22: R263Q; rs33996649

PubMed Link: 33425916

Variant Present in the following documents:

• Main text
• fcell-08-608747.pdf

View BVdb publication page

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Differential regulation of JAK/STAT-signaling in patients with ulcerative colitis and Crohn's disease.

World Journal Of Gastroenterology

Cordes, Friederike F; Foell, Dirk D; Ding, John Nik JN; Varga, Georg G; Bettenworth, Dominik D

Publication Date: 2020-07-28

Variant appearance in text: rs33996649

PubMed Link: 32821070

Variant Present in the following documents:

• Main text
• WJG-26-4055.pdf

View BVdb publication page

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Association of Functional Polymorphism in Protein Tyrosine Phosphatase Nonreceptor 22 (PTPN22) Gene with Vitiligo.

Biomarker Insights

Huraib, Ghaleb Bin GB; Al Harthi, Fahad F; Arfin, Misbahul M; Aljamal, Abdulrahman A; Alrawi, Abdulqader Saeed AS; Al-Asmari, Abdulrahman A

Publication Date: 2020

Variant appearance in text: PTPN22: R263Q

PubMed Link: 32076368

Variant Present in the following documents:

• 10.1177_1177271920903038.pdf

View BVdb publication page

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ITGAM is a risk factor to systemic lupus erythematosus and possibly a protection factor to rheumatoid arthritis in patients from Mexico.

Plos One

Ramírez-Bello, Julian J; Sun, Celi C; Valencia-Pacheco, Guillermo G; Singh, Bhupinder B; Barbosa-Cobos, Rosa Elda RE; Saavedra, Miguel A MA; López-Villanueva, Ricardo F RF; Nath, Swapan K SK

Publication Date: 2019

Variant appearance in text: PTPN22: R263Q

PubMed Link: 31774828

Variant Present in the following documents:

• pone.0224543.pdf

View BVdb publication page

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Multiple Sclerosis patients carry an increased burden of exceedingly rare genetic variants in the inflammasome regulatory genes.

Scientific Reports

Vidmar, Lovro L; Maver, Ales A; Drulović, Jelena J; Sepčić, Juraj J; Novaković, Ivana I; Ristič, Smiljana S; Šega, Saša S; Peterlin, Borut B

Publication Date: 2019-06-24

Variant appearance in text: PTPN22: 788G>A; Arg263Gln; rs33996649

PubMed Link: 31235738

Variant Present in the following documents:

• 41598_2019_45598_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Genetic Predispositions of Glucocorticoid Resistance and Therapeutic Outcomes in Polymyalgia Rheumatica and Giant Cell Arteritis.

Journal Of Clinical Medicine

Smutny, Tomas T; Barvik, Ivan I; Veleta, Tomas T; Pavek, Petr P; Soukup, Tomas T

Publication Date: 2019-04-27

Variant appearance in text: rs33996649

PubMed Link: 31035618

Variant Present in the following documents:

• Main text
• jcm-08-00582.pdf

View BVdb publication page

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A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma.

Scientific Reports

Stringer, Brett W BW; Day, Bryan W BW; D'Souza, Rochelle C J RCJ; Jamieson, Paul R PR; Ensbey, Kathleen S KS; Bruce, Zara C ZC; Lim, Yi Chieh YC; Goasdoué, Kate K; Offenhäuser, Carolin C; Akgül, Seçkin S; Allan, Suzanne S; Robertson, Thomas T; Lucas, Peter P; Tollesson, Gert G; Campbell, Scott S; Winter, Craig C; Do, Hongdo H; Dobrovic, Alexander A; Inglis, Po-Ling PL; Jeffree, Rosalind L RL; Johns, Terrance G TG; Boyd, Andrew W AW

Publication Date: 2019-03-20

Variant appearance in text: PTPN22: R263Q; rs33996649

PubMed Link: 30894629

Variant Present in the following documents:

• 41598_2019_41277_MOESM4_ESM.xlsx, sheet 7

View BVdb publication page

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Association of PTPN22 1858C/T Polymorphism with Autoimmune Diseases: A Systematic Review and Bayesian Approach.

Journal Of Clinical Medicine

Tizaoui, Kalthoum K; Kim, Seon Hui SH; Jeong, Gwang Hun GH; Kronbichler, Andreas A; Lee, Kwang Seob KS; Lee, Keum Hwa KH; Shin, Jae Il JI

Publication Date: 2019-03-12

Variant appearance in text: PTPN22: Arg263Gln

PubMed Link: 30871019

Variant Present in the following documents:

• Main text

View BVdb publication page

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Cannabinoid Signaling in the Skin: Therapeutic Potential of the "C(ut)annabinoid" System.

Molecules (Basel, Switzerland)

Tóth, Kinga Fanni KF; Ádám, Dorottya D; Bíró, Tamás T; Oláh, Attila A

Publication Date: 2019-03-06

Variant appearance in text: PTPN22: R263Q

PubMed Link: 30845666

Variant Present in the following documents:

• Main text

View BVdb publication page

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The Autoimmune-Associated Single Nucleotide Polymorphism Within PTPN22 Correlates With Clinical Outcome After Lung Transplantation.

Frontiers In Immunology

Budding, Kevin K; van Setten, Jessica J; van de Graaf, Eduard A EA; van Rossum, Oliver A OA; Kardol-Hoefnagel, Tineke T; Kwakkel-van Erp, Johanna M JM; Oudijk, Erik-Jan D ED; Hack, C Erik CE; Otten, Henderikus G HG

Publication Date: 2018

Variant appearance in text: rs33996649

PubMed Link: 30705675

Variant Present in the following documents:

• Main text
• fimmu-09-03105.pdf

View BVdb publication page

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Accelerating annotation of articles via automated approaches: evaluation of the neXtA5 curation-support tool by neXtProt.

Database : The Journal Of Biological Databases And Curation

Britan, Aurore A; Cusin, Isabelle I; Hinard, Valérie V; Mottin, Luc L; Pasche, Emilie E; Gobeill, Julien J; Rech de Laval, Valentine V; Gleizes, Anne A; Teixeira, Daniel D; Michel, Pierre-André PA; Ruch, Patrick P; Gaudet, Pascale P

Publication Date: 2018-01-01

Variant appearance in text: rs33996649

PubMed Link: 30576492

Variant Present in the following documents:

• Main text
• bay129.pdf

View BVdb publication page

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The Contribution of PTPN22 to Rheumatic Disease.

Arthritis & Rheumatology (Hoboken, N.J.)

Mustelin, Tomas T; Bottini, Nunzio N; Stanford, Stephanie M SM

Publication Date: 2019-04

Variant appearance in text: PTPN22: R263Q; rs33996649

PubMed Link: 30507064

Variant Present in the following documents:

• Main text

View BVdb publication page

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Protein Tyrosine Phosphatases: Regulators of CD4 T Cells in Inflammatory Bowel Disease.

Frontiers In Immunology

Pike, Kelly A KA; Tremblay, Michel L ML

Publication Date: 2018

Variant appearance in text: rs33996649

PubMed Link: 30429852

Variant Present in the following documents:

• Main text

View BVdb publication page

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Association of PTPN22 gene polymorphism with non-segmental vitiligo in South Indian Tamils.

Postepy Dermatologii I Alergologii

Rajendiran, Kalai Selvi KS; Rajappa, Medha M; Chandrashekar, Laxmisha L; Thappa, D M DM

Publication Date: 2018-06

Variant appearance in text: PTPN22: R263Q

PubMed Link: 30008646

Variant Present in the following documents:

• PDIA-35-32960.pdf

View BVdb publication page

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The Innate Immune System: A Trigger for Many Chronic Inflammatory Intestinal Diseases.

Inflammatory Intestinal Diseases

Kamada, Nobuhiko N; Rogler, Gerhard G

Publication Date: 2016-07

Variant appearance in text: rs33996649

PubMed Link: 29922660

Variant Present in the following documents:

• Main text

View BVdb publication page

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Clinical and genetic characteristics of pulmonary arterial hypertension in Lebanon.

Bmc Medical Genetics

Abou Hassan, Ossama K OK; Haidar, Wiam W; Nemer, Georges G; Skouri, Hadi H; Haddad, Fadi F; BouAkl, Imad I

Publication Date: 2018-05-30

Variant appearance in text: PTPN22: Arg263Gln; rs33996649

PubMed Link: 29843651

Variant Present in the following documents:

• 12881_2018_608_MOESM1_ESM.pdf

View BVdb publication page

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Regulation of autoimmune and anti-tumour T-cell responses by PTPN22.

Immunology

Brownlie, Rebecca J RJ; Zamoyska, Rose R; Salmond, Robert J RJ

Publication Date: 2018-07

Variant appearance in text: rs33996649

PubMed Link: 29512901

Variant Present in the following documents:

• Main text

View BVdb publication page

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Role of PTPN2/22 polymorphisms in pathophysiology of Crohn's disease.

World Journal Of Gastroenterology

Sharp, Robert C RC; Beg, Shazia A SA; Naser, Saleh A SA

Publication Date: 2018-02-14

Variant appearance in text: rs33996649

PubMed Link: 29456405

Variant Present in the following documents:

• Main text

View BVdb publication page

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Polymorphisms in Protein Tyrosine Phosphatase Non-receptor Type 2 and 22 (PTPN2/22) Are Linked to Hyper-Proliferative T-Cells and Susceptibility to Mycobacteria in Rheumatoid Arthritis.

Frontiers In Cellular And Infection Microbiology

Sharp, Robert C RC; Beg, Shazia A SA; Naser, Saleh A SA

Publication Date: 2018

Variant appearance in text: PTPN22: R263Q; rs33996649

PubMed Link: 29423382

Variant Present in the following documents:

• Main text
• fcimb-08-00011.pdf

View BVdb publication page

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Functional polymorphisms in pre-miR146a and pre-miR499 are associated with systemic lupus erythematosus but not with rheumatoid arthritis or Graves' disease in Mexican patients.

Oncotarget

Alemán-Ávila, Isidro I; Jiménez-Morales, Mayra M; Beltrán-Ramírez, Olga O; Barbosa-Cobos, Rosa Elda RE; Jiménez-Morales, Silvia S; Sánchez-Muñoz, Fausto F; Valencia-Pacheco, Guillermo G; Amezcua-Guerra, Luis M LM; Juárez-Vicuña, Yaneli Y; Razo-Blanco Hernández, Dulce Milagro DM; Aguilera-Cartas, María Concepción MC; López-Villanueva, Ricardo F RF; Peralta-Zaragoza, Oscar O; Tovilla-Zárate, Carlos C; Ramírez-Bello, Julian J

Publication Date: 2017-11-03

Variant appearance in text: PTPN22: R263Q

PubMed Link: 29190882

Variant Present in the following documents:

• oncotarget-08-91876.pdf

View BVdb publication page

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Protein tyrosine phosphatase nonreceptor type 22 (PTPN22) gene single nucleotide polymorphisms and its interaction with T2DM on pulmonary tuberculosis in Chinese Uygur population.

Oncotarget

Wang, Xian-Hua XH; Ma, Ai-Guo AG; Han, Xiu-Xia XX; Chen, Lei L; Liang, Hui H; Aishan-Litifu, ; Abudumijit-Ablez, ; Xue, Feng F

Publication Date: 2017-09-12

Variant appearance in text: PTPN22: R263Q; rs33996649

PubMed Link: 29029456

Variant Present in the following documents:

• Main text

View BVdb publication page

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Protein tyrosine phosphatase non-receptor 22 and C-Src tyrosine kinase genes are down-regulated in patients with rheumatoid arthritis.

Scientific Reports

Remuzgo-Martínez, Sara S; Genre, Fernanda F; Castañeda, Santos S; Corrales, Alfonso A; Moreno-Fresneda, Pablo P; Ubilla, Begoña B; Mijares, Verónica V; Portilla, Virginia V; González-Vela, Jesús J; Pina, Trinitario T; Ocejo-Vinyals, Gonzalo G; Irure-Ventura, Juan J; Blanco, Ricardo R; Martín, Javier J; Llorca, Javier J; López-Mejías, Raquel R; González-Gay, Miguel A MA

Publication Date: 2017-09-05

Variant appearance in text: PTPN22: R263Q; rs33996649

PubMed Link: 28874816

Variant Present in the following documents:

• Main text
• 41598_2017_Article_10915.pdf

View BVdb publication page

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Inflammation-Related Gene Polymorphisms Associated With Primary Immune Thrombocytopenia.

Frontiers In Immunology

Li, Ju J; Ma, Sai S; Shao, Linlin L; Ma, Chunhong C; Gao, Chengjiang C; Zhang, Xiao-Hui XH; Hou, Ming M; Peng, Jun J

Publication Date: 2017

Variant appearance in text: rs33996649

PubMed Link: 28702029

Variant Present in the following documents:

• Main text

View BVdb publication page

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Association Between Protein Tyrosine Phosphatase Non-Receptor Type 22 (PTPN22) Polymorphisms and Risk of Ankylosing Spondylitis: A Meta-analysis.

Medical Science Monitor : International Medical Journal Of Experimental And Clinical Research

Wang, Weiming W; Meng, Xiantao X; Liu, Yupeng Y; Ma, Xiaojun X; Zhang, Qian Q; Li, Chunhui C; Li, Chenye C; Ren, Liubao L

Publication Date: 2017-05-30

Variant appearance in text: PTPN22: R263Q

PubMed Link: 28555069

Variant Present in the following documents:

• medscimonit-23-2619.pdf

View BVdb publication page

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Next-generation DNA sequencing identifies novel gene variants and pathways involved in specific language impairment.

Scientific Reports

Chen, Xiaowei Sylvia XS; Reader, Rose H RH; Hoischen, Alexander A; Veltman, Joris A JA; Simpson, Nuala H NH; Francks, Clyde C; Newbury, Dianne F DF; Fisher, Simon E SE

Publication Date: 2017-04-25

Variant appearance in text: PTPN22: R263Q; rs33996649

PubMed Link: 28440294

Variant Present in the following documents:

• srep46105-s2.xls, sheet 9

View BVdb publication page

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Genotype-Phenotype Associations of the CD-Associated Single Nucleotide Polymorphism within the Gene Locus Encoding Protein Tyrosine Phosphatase Non-Receptor Type 22 in Patients of the Swiss IBD Cohort.

Plos One

Spalinger, Marianne R MR; Zeitz, Jonas J; Biedermann, Luc L; Rossel, Jean-Benoit JB; Sulz, Michael C MC; Frei, Pascal P; Scharl, Sylvie S; Vavricka, Stephan R SR; Fried, Michael M; Rogler, Gerhard G; Scharl, Michael M; ,

Publication Date: 2016

Variant appearance in text: rs33996649

PubMed Link: 27467733

Variant Present in the following documents:

• Main text

View BVdb publication page

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Genetic Association of PTPN22 Polymorphisms with Autoimmune Hepatitis and Primary Biliary Cholangitis in Japan.

Scientific Reports

Umemura, Takeji T; Joshita, Satoru S; Yamazaki, Tomoo T; Komatsu, Michiharu M; Katsuyama, Yoshihiko Y; Yoshizawa, Kaname K; Tanaka, Eiji E; Ota, Masao M

Publication Date: 2016-07-11

Variant appearance in text: rs33996649

PubMed Link: 27406031

Variant Present in the following documents:

• Main text

View BVdb publication page

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The role for protein tyrosine phosphatase non-receptor type 22 in regulating intestinal homeostasis.

United European Gastroenterology Journal

Spalinger, Marianne R MR; Scharl, Michael M

Publication Date: 2016-06

Variant appearance in text: rs33996649

PubMed Link: 27403297

Variant Present in the following documents:

• Main text

View BVdb publication page

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Molecular analysis of urothelial cancer cell lines for modeling tumor biology and drug response.

Oncogene

Nickerson, M L ML; Witte, N N; Im, K M KM; Turan, S S; Owens, C C; Misner, K K; Tsang, S X SX; Cai, Z Z; Wu, S S; Dean, M M; Costello, J C JC; Theodorescu, D D

Publication Date: 2017-01-05

Variant appearance in text: PTPN22: R263Q; rs33996649

PubMed Link: 27270441

Variant Present in the following documents:

• onc2016172x3.xls, sheet 3

View BVdb publication page

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Serum Immunoglobulin G Levels to Porphyromonas gingivalis Peptidylarginine Deiminase Affect Clinical Response to Biological Disease-Modifying Antirheumatic Drug in Rheumatoid Arthritis.

Plos One

Kobayashi, Tetsuo T; Ito, Satoshi S; Kobayashi, Daisuke D; Shimada, Atsushi A; Narita, Ichiei I; Murasawa, Akira A; Nakazono, Kiyoshi K; Yoshie, Hiromasa H

Publication Date: 2016

Variant appearance in text: PTPN22: R263Q; rs33996649

PubMed Link: 27111223

Variant Present in the following documents:

• Main text
• pone.0154182.pdf

View BVdb publication page

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Role of PTPN22 and CSK gene polymorphisms as predictors of susceptibility and clinical heterogeneity in patients with Henoch-Schönlein purpura (IgA vasculitis).

Arthritis Research & Therapy

López-Mejías, Raquel R; Genre, Fernanda F; Remuzgo-Martínez, Sara S; Pérez, Belén Sevilla BS; Castañeda, Santos S; Llorca, Javier J; Ortego-Centeno, Norberto N; Ubilla, Begoña B; Mijares, Verónica V; Pina, Trinitario T; Calvo-Río, Vanesa V; Palmou, Natalia N; Miranda-Filloy, José A JA; Parejo, Antonio Navas AN; Argila, Diego D; Sánchez-Pérez, Javier J; Rubio, Esteban E; Luque, Manuel León ML; Blanco-Madrigal, Juan María JM; Galíndez-Aguirregoikoa, Eva E; Ocejo-Vinyals, J Gonzalo JG; Martín, Javier J; Blanco, Ricardo R; González-Gay, Miguel A MA

Publication Date: 2015-10-13

Variant appearance in text: PTPN22: R263Q; rs33996649

PubMed Link: 26458874

Variant Present in the following documents:

• Main text
• 13075_2015_Article_796.pdf

View BVdb publication page

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Immunogenetics of systemic lupus erythematosus: A comprehensive review.

Journal Of Autoimmunity

Ghodke-Puranik, Yogita Y; Niewold, Timothy B TB

Publication Date: 2015-11

Variant appearance in text: PTPN22: Arg263Gln

PubMed Link: 26324017

Variant Present in the following documents:

• Main text

View BVdb publication page

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Application of whole genome and RNA sequencing to investigate the genomic landscape of common variable immunodeficiency disorders.

Clinical Immunology (Orlando, Fla.)

van Schouwenburg, Pauline A PA; Davenport, Emma E EE; Kienzler, Anne-Kathrin AK; Marwah, Ishita I; Wright, Benjamin B; Lucas, Mary M; Malinauskas, Tomas T; Martin, Hilary C HC; , ; Lockstone, Helen E HE; Cazier, Jean-Baptiste JB; Chapel, Helen M HM; Knight, Julian C JC; Patel, Smita Y SY

Publication Date: 2015-10

Variant appearance in text: PTPN22: 750+2404G>A; R263Q

PubMed Link: 26122175

Variant Present in the following documents:

• NIHMS64345-supplement-Supplementary_tables.xlsx, sheet 9

View BVdb publication page

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Role of protein tyrosine phosphatases in regulating the immune system: implications for chronic intestinal inflammation.

Inflammatory Bowel Diseases

Spalinger, Marianne R MR; McCole, Declan F DF; Rogler, Gerhard G; Scharl, Michael M

Publication Date: 2015-03

Variant appearance in text: rs33996649

PubMed Link: 25581833

Variant Present in the following documents:

• Main text

View BVdb publication page

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Whole-genome sequencing of the world's oldest people.

Plos One

Gierman, Hinco J HJ; Fortney, Kristen K; Roach, Jared C JC; Coles, Natalie S NS; Li, Hong H; Glusman, Gustavo G; Markov, Glenn J GJ; Smith, Justin D JD; Hood, Leroy L; Coles, L Stephen LS; Kim, Stuart K SK

Publication Date: 2014

Variant appearance in text: PTPN22: R263Q; rs33996649

PubMed Link: 25390934

Variant Present in the following documents:

• pone.0112430.s004.xlsx, sheet 1

View BVdb publication page

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The eSNV-detect: a computational system to identify expressed single nucleotide variants from transcriptome sequencing data.

Nucleic Acids Research

Tang, Xiaojia X; Baheti, Saurabh S; Shameer, Khader K; Thompson, Kevin J KJ; Wills, Quin Q; Niu, Nifang N; Holcomb, Ilona N IN; Boutet, Stephane C SC; Ramakrishnan, Ramesh R; Kachergus, Jennifer M JM; Kocher, Jean-Pierre A JP; Weinshilboum, Richard M RM; Wang, Liewei L; Thompson, E Aubrey EA; Kalari, Krishna R KR

Publication Date: 2014-12-16

Variant appearance in text: PTPN22: R263Q; rs33996649

PubMed Link: 25352556

Variant Present in the following documents:

• supp_gku1005_nar-01266-met-n-2014-File012.xlsx, sheet 13
• supp_gku1005_nar-01266-met-n-2014-File012.xlsx, sheet 7

View BVdb publication page

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Protein tyrosine phosphatase PTPN22 +1858C/T polymorphism is associated with active vitiligo.

Experimental And Therapeutic Medicine

Garcia-Melendez, Martha Elena ME; Salinas-Santander, Mauricio M; Sanchez-Dominguez, Celia C; Gonzalez-Cardenas, Hugo H; Cerda-Flores, Ricardo M RM; Ocampo-Candiani, Jorge J; Ortiz-López, Rocío R

Publication Date: 2014-11

Variant appearance in text: PTPN22: R263Q

PubMed Link: 25289035

Variant Present in the following documents:

• etm-08-05-1433.pdf

View BVdb publication page

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NCI-60 whole exome sequencing and pharmacological CellMiner analyses.

Plos One

Reinhold, William C WC; Varma, Sudhir S; Sousa, Fabricio F; Sunshine, Margot M; Abaan, Ogan D OD; Davis, Sean R SR; Reinhold, Spencer W SW; Kohn, Kurt W KW; Morris, Joel J; Meltzer, Paul S PS; Doroshow, James H JH; Pommier, Yves Y

Publication Date: 2014

Variant appearance in text: PTPN22: R263Q; rs33996649

PubMed Link: 25032700

Variant Present in the following documents:

• pone.0101670.s004.xlsx, sheet 1

View BVdb publication page

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PTPN22: the archetypal non-HLA autoimmunity gene.

Nature Reviews. Rheumatology

Stanford, Stephanie M SM; Bottini, Nunzio N

Publication Date: 2014-10

Variant appearance in text: PTPN22: Arg263Gln; rs33996649

PubMed Link: 25003765

Variant Present in the following documents:

• Main text

View BVdb publication page

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Systemic Lupus Erythematosus: Old and New Susceptibility Genes versus Clinical Manifestations.

Current Genomics

J, De Azevêdo Silva de AS; C, Addobbati A; P, Sandrin-Garcia SG; S, Crovella C

Publication Date: 2014-02

Variant appearance in text: Lyp: R263Q

PubMed Link: 24653663

Variant Present in the following documents:

• Main text
• CG-15-52.pdf

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Genetics of the type I interferon pathway in systemic lupus erythematosus.

International Journal Of Clinical Rheumatology

Ghodke-Puranik, Yogita Y; Niewold, Timothy B TB

Publication Date: 2013-12-01

Variant appearance in text: PTPN22: Arg263Gln

PubMed Link: 24416080

Variant Present in the following documents:

• Main text

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Tyrosine phosphatase PTPN22: multifunctional regulator of immune signaling, development, and disease.

Annual Review Of Immunology

Bottini, Nunzio N; Peterson, Erik J EJ

Publication Date: 2014

Variant appearance in text: PTPN22: R263Q; rs33996649

PubMed Link: 24364806

Variant Present in the following documents:

• Main text

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PTPN22 association in systemic lupus erythematosus (SLE) with respect to individual ancestry and clinical sub-phenotypes.

Plos One

Namjou, Bahram B; Kim-Howard, Xana X; Sun, Celi C; Adler, Adam A; Chung, Sharon A SA; Kaufman, Kenneth M KM; Kelly, Jennifer A JA; Glenn, Stuart B SB; Guthridge, Joel M JM; Scofield, Robert H RH; Kimberly, Robert P RP; Brown, Elizabeth E EE; Alarcón, Graciela S GS; Edberg, Jeffrey C JC; Kim, Jae-Hoon JH; Choi, Jiyoung J; Ramsey-Goldman, Rosalind R; Petri, Michelle A MA; Reveille, John D JD; Vilá, Luis M LM; Boackle, Susan A SA; Freedman, Barry I BI; Tsao, Betty P BP; Langefeld, Carl D CD; Vyse, Timothy J TJ; Jacob, Chaim O CO; Pons-Estel, Bernardo B; , ; Niewold, Timothy B TB; Moser Sivils, Kathy L KL; Merrill, Joan T JT; Anaya, Juan-Manuel JM; Gilkeson, Gary S GS; Gaffney, Patrick M PM; Bae, Sang-Cheol SC; Alarcón-Riquelme, Marta E ME; , ; Harley, John B JB; Criswell, Lindsey A LA; James, Judith A JA; Nath, Swapan K SK

Publication Date: 2013

Variant appearance in text: PTPN22: R263Q; rs33996649

PubMed Link: 23950893

Variant Present in the following documents:

• Main text

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Identification of the PTPN22 functional variant R620W as susceptibility genetic factor for giant cell arteritis.

Annals Of The Rheumatic Diseases

Serrano, A A; Márquez, A A; Mackie, S L SL; Carmona, F D FD; Solans, R R; Miranda-Filloy, J A JA; Hernández-Rodríguez, J J; Cid, M C MC; Castañeda, S S; Morado, I C IC; Narváez, J J; Blanco, R R; Sopeña, B B; García-Villanueva, M J MJ; Monfort, J J; Ortego-Centeno, N N; Unzurrunzaga, A A; Marí-Alfonso, B B; Sánchez Martín, J J; de Miguel, E E; Magro, C C; Raya, E E; , ; , ; Braun, N N; Latus, J J; Molberg, O O; Lie, B A BA; Moosig, F F; Witte, T T; Morgan, A W AW; González-Gay, M A MA; Martín, J J

Publication Date: 2013-11

Variant appearance in text: PTPN22: R263Q; rs33996649

PubMed Link: 23946333

Variant Present in the following documents:

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Lack of association between the protein tyrosine phosphatase non-receptor type 22 R263Q and R620W functional genetic variants and endogenous non-anterior uveitis.

Molecular Vision

Cénit, María Carmen MC; Márquez, Ana A; Cordero-Coma, Miguel M; Fonollosa, Alejandro A; Llorenç, Victor V; Artaraz, Joseba J; Díaz Valle, David D; Blanco, Ricardo R; Cañal, Joaquín J; Salom, David D; García Serrano, José Luis JL; de Ramón, Enrique E; José del Rio, María M; Gorroño-Echebarría, Marina Begoña MB; Martín-Villa, José Manuel JM; Molins, Blanca B; Ortego-Centeno, Norberto N; Martín, Javier J

Publication Date: 2013

Variant appearance in text: PTPN22: R263Q; rs33996649

PubMed Link: 23559857

Variant Present in the following documents:

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The autoimmune-predisposing variant of lymphoid tyrosine phosphatase favors T helper 1 responses.

Human Immunology

Vang, Torkel T; Landskron, Johannes J; Viken, Marte K MK; Oberprieler, Nikolaus N; Torgersen, Knut M KM; Mustelin, Tomas T; Tasken, Kjetil K; Tautz, Lutz L; Rickert, Robert C RC; Lie, Benedicte A BA

Publication Date: 2013-05

Variant appearance in text: PTPN22: R263Q; rs33996649

PubMed Link: 23333624

Variant Present in the following documents:

• Main text

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Meta-analysis of 125 rheumatoid arthritis-related single nucleotide polymorphisms studied in the past two decades.

Plos One

Jiang, Yongshuai Y; Zhang, Ruijie R; Zheng, Jiajia J; Liu, Panpan P; Tang, Guoping G; Lv, Hongchao H; Zhang, Lanying L; Shang, Zhenwei Z; Zhan, Yuanbo Y; Lv, Wenhua W; Shi, Miao M; Zhang, Ruimin R

Publication Date: 2012

Variant appearance in text: rs33996649

PubMed Link: 23251581

Variant Present in the following documents:

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Potential of ayurgenomics approach in complex trait research: leads from a pilot study on rheumatoid arthritis.

Plos One

Juyal, Ramesh C RC; Negi, Sapna S; Wakhode, Preeti P; Bhat, Sulekha S; Bhat, Bheema B; Thelma, B K BK

Publication Date: 2012

Variant appearance in text: PTPN22: R263Q

PubMed Link: 23049851

Variant Present in the following documents:

• pone.0045752.pdf

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Biochemical and functional studies of lymphoid-specific tyrosine phosphatase (Lyp) variants S201F and R266W.

Plos One

Liu, Jing J; Chen, Ming M; Li, Rong R; Yang, Fan F; Shi, Xuanren X; Zhu, Lichao L; Wang, Hong-Mei HM; Yao, Wei W; Liu, Qiji Q; Meng, Fan-Guo FG; Sun, Jin-Peng JP; Pang, Qi Q; Yu, Xiao X

Publication Date: 2012

Variant appearance in text: PTPN22: R263Q; rs33996649

PubMed Link: 22952725

Variant Present in the following documents:

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High basal activity of the PTPN22 gain-of-function variant blunts leukocyte responsiveness negatively affecting IL-10 production in ANCA vasculitis.

Plos One

Cao, Yali Y; Yang, Jiajin J; Colby, Kerry K; Hogan, Susan L SL; Hu, Yichun Y; Jennette, Caroline E CE; Berg, Elisabeth A EA; Zhang, Youkang Y; Jennette, J Charles JC; Falk, Ronald J RJ; Preston, Gloria A GA

Publication Date: 2012

Variant appearance in text: PTPN22: R263Q; rs33996649

PubMed Link: 22880107

Variant Present in the following documents:

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The genetic basis of graves' disease.

Current Genomics

Płoski, Rafał R; Szymański, Konrad K; Bednarczuk, Tomasz T

Publication Date: 2011-12

Variant appearance in text: PTPN22: R263Q

PubMed Link: 22654555

Variant Present in the following documents:

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Overexpression of the autoimmunity-associated phosphatase PTPN22 promotes survival of antigen-stimulated CLL cells by selectively activating AKT.

Blood

Negro, Roberto R; Gobessi, Stefania S; Longo, Pablo G PG; He, Yantao Y; Zhang, Zhong-Yin ZY; Laurenti, Luca L; Efremov, Dimitar G DG

Publication Date: 2012-06-28

Variant appearance in text: PTPN22: R263Q

PubMed Link: 22569400

Variant Present in the following documents:

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PTPN22 splice forms: a new role in rheumatoid arthritis.

Genome Medicine

Diaz-Gallo, Lina-Marcela LM; Martin, Javier J

Publication Date: 2012-02-24

Variant appearance in text: PTPN22: R263Q; rs33996649

PubMed Link: 22364193

Variant Present in the following documents:

• Main text

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