PTPN22 c.385T>A ;(p.C129S)

Variant ID: 1-114400383-A-T

NM_015967.5(PTPN22):c.385T>A;(p.C129S)

This variant was identified in 5 publications

View GRCh38 version.




Publications:


Redox regulation of PTPN22 affects the severity of T-cell-dependent autoimmune inflammation.

Elife
James, Jaime J; Chen, Yifei Y; Hernandez, Clara M CM; Forster, Florian F; Dagnell, Markus M; Cheng, Qing Q; Saei, Amir A AA; Gharibi, Hassan H; Lahore, Gonzalo Fernandez GF; Åstrand, Annika A; Malhotra, Rajneesh R; Malissen, Bernard B; Zubarev, Roman A RA; Arnér, Elias S J ESJ; Holmdahl, Rikard R
Publication Date: 2022-05-19

Variant appearance in text: PTPN22: C129S
PubMed Link: 35587260
Variant Present in the following documents:
  • Main text
  • elife-74549.pdf
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Identification and structure-function analyses of an allosteric inhibitor of the tyrosine phosphatase PTPN22.

The Journal Of Biological Chemistry
Li, Kangshuai K; Hou, Xuben X; Li, Ruirui R; Bi, Wenxiang W; Yang, Fan F; Chen, Xu X; Xiao, Peng P; Liu, Tiantian T; Lu, Tiange T; Zhou, Yuan Y; Tian, Zhaomei Z; Shen, Yuemao Y; Zhang, Yingkai Y; Wang, Jiangyun J; Fang, Hao H; Sun, Jinpeng J; Yu, Xiao X
Publication Date: 2019-05-24

Variant appearance in text: PTPN22: C129S
PubMed Link: 30979725
Variant Present in the following documents:
  • Main text
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Gold(I) phosphine mediated selective inhibition of lymphoid tyrosine phosphatase.

Journal Of Inorganic Biochemistry
Karver, Mark R MR; Krishnamurthy, Divya D; Bottini, Nunzio N; Barrios, Amy M AM
Publication Date: 2010-03

Variant appearance in text: PTPN22: C129S
PubMed Link: 20083307
Variant Present in the following documents:
  • Main text
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Crystal structure of the human lymphoid tyrosine phosphatase catalytic domain: insights into redox regulation .

Biochemistry
Tsai, Sophia J SJ; Sen, Udayaditya U; Zhao, Lei L; Greenleaf, William B WB; Dasgupta, Jhimli J; Fiorillo, Edoardo E; Orrú, Valeria V; Bottini, Nunzio N; Chen, Xiaojiang S XS
Publication Date: 2009-06-09

Variant appearance in text: PTPN22: C129S
PubMed Link: 19371084
Variant Present in the following documents:
  • Main text
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Structure, inhibitor, and regulatory mechanism of Lyp, a lymphoid-specific tyrosine phosphatase implicated in autoimmune diseases.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Yu, Xiao X; Sun, Jin-Peng JP; He, Yantao Y; Guo, Xiaoling X; Liu, Sijiu S; Zhou, Bo B; Hudmon, Andy A; Zhang, Zhong-Yin ZY
Publication Date: 2007-12-11

Variant appearance in text: Lyp: C129S
PubMed Link: 18056643
Variant Present in the following documents:
  • Main text
View BVdb publication page