Publications:

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Sensitive Quantification of Cell-Free Tumor DNA for Early Detection of Recurrence in Colorectal Cancer.

Frontiers In Genetics

Stasik, Sebastian S; Mende, Marika M; Schuster, Caroline C; Mahler, Sandra S; Aust, Daniela D; Tannapfel, Andrea A; Reinacher-Schick, Anke A; Baretton, Gustavo G; Krippendorf, Claudia C; Bornhäuser, Martin M; Ehninger, Gerhard G; Folprecht, Gunnar G; Thiede, Christian C

Publication Date: 2021

Variant appearance in text: NRAS: 350A>G; Lys117Arg

PubMed Link: 35069704

Variant Present in the following documents:

• fgene-12-811291.pdf

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Association of clonal hematopoiesis with chronic obstructive pulmonary disease.

Blood

Miller, Peter G PG; Qiao, Dandi D; Rojas-Quintero, Joselyn J; Honigberg, Michael C MC; Sperling, Adam S AS; Gibson, Christopher J CJ; Bick, Alexander G AG; Niroula, Abhishek A; McConkey, Marie E ME; Sandoval, Brittany B; Miller, Brian C BC; Shi, Weiwei W; Viswanathan, Kaushik K; Leventhal, Matthew M; Werner, Lillian L; Moll, Matthew M; Cade, Brian E BE; Barr, R Graham RG; Correa, Adolfo A; Cupples, L Adrienne LA; Gharib, Sina A SA; Jain, Deepti D; Gogarten, Stephanie M SM; Lange, Leslie A LA; London, Stephanie J SJ; Manichaikul, Ani A; O'Connor, George T GT; Oelsner, Elizabeth C EC; Redline, Susan S; Rich, Stephen S SS; Rotter, Jerome I JI; Ramachandran, Vasan V; Yu, Bing B; Sholl, Lynette L; Neuberg, Donna D; Jaiswal, Siddhartha S; Levy, Bruce D BD; Owen, Caroline A CA; Natarajan, Pradeep P; Silverman, Edwin K EK; van Galen, Peter P; Tesfaigzi, Yohannes Y; Cho, Michael H MH; Ebert, Benjamin L BL; ,

Publication Date: 2022-01-20

Variant appearance in text: NRAS: K117R

PubMed Link: 34855941

Variant Present in the following documents:

• 10.1182-2021013531_bloodbld2021013531-suppl1.pdf
• bloodBLD2021013531-suppl1.pdf

View BVdb publication page

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Molecular and functional profiling identifies therapeutically targetable vulnerabilities in plasmablastic lymphoma.

Nature Communications

Frontzek, Fabian F; Staiger, Annette M AM; Zapukhlyak, Myroslav M; Xu, Wendan W; Bonzheim, Irina I; Borgmann, Vanessa V; Sander, Philip P; Baptista, Maria Joao MJ; Heming, Jan-Niklas JN; Berning, Philipp P; Wullenkord, Ramona R; Erdmann, Tabea T; Lutz, Mathias M; Veratti, Pia P; Ehrenfeld, Sophia S; Wienand, Kirsty K; Horn, Heike H; Goodlad, John R JR; Wilson, Matthew R MR; Anagnostopoulos, Ioannis I; Lamping, Mario M; Gonzalez-Barca, Eva E; Climent, Fina F; Salar, Antonio A; Castellvi, Josep J; Abrisqueta, Pau P; Menarguez, Javier J; Aldamiz, Teresa T; Richter, Julia J; Klapper, Wolfram W; Tzankov, Alexandar A; Dirnhofer, Stefan S; Rosenwald, Andreas A; Mate, José Luis JL; Tapia, Gustavo G; Lenz, Peter P; Miething, Cornelius C; Hartmann, Wolfgang W; Chapuy, Björn B; Fend, Falko F; Ott, German G; Navarro, José-Tomas JT; Grau, Michael M; Lenz, Georg G

Publication Date: 2021-08-31

Variant appearance in text: NRAS: 350A>G; K117R

PubMed Link: 34465776

Variant Present in the following documents:

• 41467_2021_25405_MOESM7_ESM.xlsx, sheet 2
• 41467_2021_25405_MOESM9_ESM.xlsx, sheet 1

View BVdb publication page

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CD133-directed CAR T-cells for MLL leukemia: on-target, off-tumor myeloablative toxicity.

Leukemia

Bueno, Clara C; Velasco-Hernandez, Talia T; Gutiérrez-Agüera, Francisco F; Zanetti, Samanta Romina SR; Baroni, Matteo L ML; Sánchez-Martínez, Diego D; Molina, Oscar O; Closa, Adria A; Agraz-Doblás, Antonio A; Marín, Pedro P; Eyras, Eduardo E; Varela, Ignacio I; Menéndez, Pablo P

Publication Date: 2019-08

Variant appearance in text: NRAS: K117R

PubMed Link: 30778134

Variant Present in the following documents:

• 41375_2019_Article_418.pdf

View BVdb publication page

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Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One

Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS

Publication Date: 2018

Variant appearance in text: NRAS: K117R

PubMed Link: 29698444

Variant Present in the following documents:

• pone.0196434.s001.xlsx, sheet 1
• pone.0196434.s001.xlsx, sheet 3
• pone.0196434.s001.xlsx, sheet 2

View BVdb publication page

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Mutation status and prognostic values of KRAS, NRAS, BRAF and PIK3CA in 353 Chinese colorectal cancer patients.

Scientific Reports

Guo, Fang F; Gong, Hai H; Zhao, Huanhuan H; Chen, Jing J; Zhang, Yiming Y; Zhang, Lihua L; Shi, Xin X; Zhang, Aifeng A; Jin, Hui H; Zhang, Jianqiong J; He, Youji Y

Publication Date: 2018-04-17

Variant appearance in text: NRAS: K117R

PubMed Link: 29666387

Variant Present in the following documents:

• 41598_2018_Article_24306.pdf

View BVdb publication page

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Comprehensive genomic sequencing detects important genetic differences between right-sided and left-sided colorectal cancer.

Oncotarget

Shimada, Yoshifumi Y; Kameyama, Hitoshi H; Nagahashi, Masayuki M; Ichikawa, Hiroshi H; Muneoka, Yusuke Y; Yagi, Ryoma R; Tajima, Yosuke Y; Okamura, Takuma T; Nakano, Masato M; Sakata, Jun J; Kobayashi, Takashi T; Nogami, Hitoshi H; Maruyama, Satoshi S; Takii, Yasumasa Y; Hayashida, Tetsu T; Takaishi, Hiromasa H; Kitagawa, Yuko Y; Oki, Eiji E; Konishi, Tsuyoshi T; Ishida, Fumio F; Kudo, Shin-Ei SE; Ring, Jennifer E JE; Protopopov, Alexei A; Lyle, Stephen S; Ling, Yiwei Y; Okuda, Shujiro S; Ishikawa, Takashi T; Akazawa, Kohei K; Takabe, Kazuaki K; Wakai, Toshifumi T

Publication Date: 2017-11-07

Variant appearance in text: NRAS: K117R

PubMed Link: 29212173

Variant Present in the following documents:

• oncotarget-08-93567-s003.xlsx, sheet 1

View BVdb publication page

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Molecular characterization of circulating colorectal tumor cells defines genetic signatures for individualized cancer care.

Oncotarget

Kong, Say Li SL; Liu, Xingliang X; Suhaimi, Nur-Afidah Mohamed NM; Koh, Kenneth Jia Hao KJH; Hu, Min M; Lee, Daniel Yoke San DYS; Cima, Igor I; Phyo, Wai Min WM; Lee, Esther Xing Wei EXW; Tai, Joyce A JA; Foong, Yu Miin YM; Vo, Jess Honganh JH; Koh, Poh Koon PK; Zhang, Tong T; Ying, Jackie Y JY; Lim, Bing B; Tan, Min-Han MH; Hillmer, Axel M AM

Publication Date: 2017-09-15

Variant appearance in text: NRAS: K117R

PubMed Link: 28978093

Variant Present in the following documents:

• oncotarget-08-68026-s002.xlsx, sheet 3

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Extreme assay sensitivity in molecular diagnostics further unveils intratumour heterogeneity in metastatic colorectal cancer as well as artifactual low-frequency mutations in the KRAS gene.

British Journal Of Cancer

Mariani, Sara S; Bertero, Luca L; Osella-Abate, Simona S; Di Bello, Cristiana C; Francia di Celle, Paola P; Coppola, Vittoria V; Sapino, Anna A; Cassoni, Paola P; Marchiò, Caterina C

Publication Date: 2017-07-25

Variant appearance in text: NRAS: K117R

PubMed Link: 28618430

Variant Present in the following documents:

• bjc2017170a.pdf

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Prevalence of NRAS, PTEN and AKT1 gene mutations in the central nervous system metastases of non-small cell lung cancer.

Brain Tumor Pathology

Nicoś, Marcin M; Krawczyk, Paweł P; Jarosz, Bożena B; Sawicki, Marek M; Trojanowski, Tomasz T; Milanowski, Janusz J

Publication Date: 2017-01

Variant appearance in text: NRAS: K117R

PubMed Link: 28097440

Variant Present in the following documents:

• Main text
• 10014_2016_Article_276.pdf

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BRAF and RAS mutations as prognostic factors in metastatic colorectal cancer patients undergoing liver resection.

British Journal Of Cancer

Schirripa, M M; Bergamo, F F; Cremolini, C C; Casagrande, M M; Lonardi, S S; Aprile, G G; Yang, D D; Marmorino, F F; Pasquini, G G; Sensi, E E; Lupi, C C; De Maglio, G G; Borrelli, N N; Pizzolitto, S S; Fasola, G G; Bertorelle, R R; Rugge, M M; Fontanini, G G; Zagonel, V V; Loupakis, F F; Falcone, A A

Publication Date: 2015-06-09

Variant appearance in text: NRAS: K117R

PubMed Link: 25942399

Variant Present in the following documents:

View BVdb publication page

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