Publications:

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Meta-analysis of commonly mutated genes in leptomeningeal carcinomatosis.

Peerj

Congur, Irem I; Koni, Ekin E; Onat, Onur Emre OE; Tokcaer Keskin, Zeynep Z

Publication Date: 2023

Variant appearance in text: NRAS: p110a

PubMed Link: 37096065

Variant Present in the following documents:

• peerj-11-15250.pdf

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Somatic activating BRAF variants cause isolated lymphatic malformations.

Hgg Advances

Zenner, Kaitlyn K; Jensen, Dana M DM; Dmyterko, Victoria V; Shivaram, Giridhar M GM; Myers, Candace T CT; Paschal, Cate R CR; Rudzinski, Erin R ER; Pham, Minh-Hang M MM; Cheng, V Chi VC; Manning, Scott C SC; Bly, Randall A RA; Ganti, Sheila S; Perkins, Jonathan A JA; Bennett, James T JT

Publication Date: 2022-04-14

Variant appearance in text: NRAS: p110a

PubMed Link: 35373151

Variant Present in the following documents:

• mmc2.pdf
• main.pdf

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Recent Developments in Targeting RAS Downstream Effectors for RAS-Driven Cancer Therapy.

Molecules (Basel, Switzerland)

Tatli, Ozge O; Dinler Doganay, Gizem G

Publication Date: 2021-12-14

Variant appearance in text: NRAS: p110a

PubMed Link: 34946644

Variant Present in the following documents:

• Main text
• molecules-26-07561.pdf

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Recent Developments in Targeting RAS Downstream Effectors for RAS-Driven Cancer Therapy.

Molecules (Basel, Switzerland)

Tatli, Ozge O; Dinler Doganay, Gizem G

Publication Date: 2021-12-14

Variant appearance in text: NRAS: p110a

PubMed Link: 34946644

Variant Present in the following documents:

• Main text
• molecules-26-07561.pdf

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Omipalisib Inhibits Esophageal Squamous Cell Carcinoma Growth Through Inactivation of Phosphoinositide 3-Kinase (PI3K)/AKT/Mammalian Target of Rapamycin (mTOR) and ERK Signaling.

Medical Science Monitor : International Medical Journal Of Experimental And Clinical Research

Zhu, Dong-Shan DS; Dong, Jing-Yao JY; Xu, Yao-Yao YY; Zhang, Xin-Tong XT; Fu, Shi-Bo SB; Liu, Wei W

Publication Date: 2020-08-17

Variant appearance in text: NRAS: p110a

PubMed Link: 32804918

Variant Present in the following documents:

• medscimonit-26-e927106.pdf

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Loss of miR-143 and miR-145 in condyloma acuminatum promotes cellular proliferation and inhibits apoptosis by targeting NRAS.

Royal Society Open Science

Liu, Xiaoyan X; Zhang, Yu Y; Wang, Su S; Liu, Guoying G; Ruan, Liming L

Publication Date: 2018-08

Variant appearance in text: NRAS: p110a

PubMed Link: 30225000

Variant Present in the following documents:

• rsos172376.pdf

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The Impact of Cetuximab Plus AKT- or mTOR- Inhibitor in a Patient-Derived Colon Cancer Cell Model with Wild-Type RAS and PIK3CA Mutation.

Journal Of Cancer

Kim, Ju Sun JS; Kim, Jung Eun JE; Kim, Kyung K; Lee, Jeeyun J; Park, Joon Oh JO; Lim, Ho Yeong HY; Park, Young Suk YS; Kang, Won Ki WK; Kim, Seung Tae ST

Publication Date: 2017

Variant appearance in text: NRAS: p110a

PubMed Link: 28928860

Variant Present in the following documents:

• Main text
• jcav08p2713.pdf

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Computational Modeling of complete HOXB13 protein for predicting the functional effect of SNPs and the associated role in hereditary prostate cancer.

Scientific Reports

Chandrasekaran, Gopalakrishnan G; Hwang, Eu Chang EC; Kang, Taek Won TW; Kwon, Dong Deuk DD; Park, Kwangsung K; Lee, Je-Jung JJ; Lakshmanan, Vinoth-Kumar VK

Publication Date: 2017-03-08

Variant appearance in text: N-ras: P110A

PubMed Link: 28272408

Variant Present in the following documents:

• srep43830.pdf

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PIK3CA dependence and sensitivity to therapeutic targeting in urothelial carcinoma.

Bmc Cancer

Ross, R L RL; McPherson, H R HR; Kettlewell, L L; Shnyder, S D SD; Hurst, C D CD; Alder, O O; Knowles, M A MA

Publication Date: 2016-07-28

Variant appearance in text: NRAS: p110a

PubMed Link: 27465249

Variant Present in the following documents:

• Main text
• 12885_2016_Article_2570.pdf

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Precision medicine in colorectal cancer: the molecular profile alters treatment strategies.

Therapeutic Advances In Medical Oncology

Tran, Nguyen H NH; Cavalcante, Ludmila L LL; Lubner, Sam J SJ; Mulkerin, Daniel L DL; LoConte, Noelle K NK; Clipson, Linda L; Matkowskyj, Kristina A KA; Deming, Dustin A DA

Publication Date: 2015-09

Variant appearance in text: NRAS: p110a

PubMed Link: 26327923

Variant Present in the following documents:

• Main text

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The phosphoinositide 3-kinase pathway and therapy resistance in cancer.

F1000Prime Reports

Brown, Kristin K KK; Toker, Alex A

Publication Date: 2015

Variant appearance in text: NRAS: p110a

PubMed Link: 25750731

Variant Present in the following documents:

• biolrep-07-13.pdf

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Synergistic effects of targeted PI3K signaling inhibition and chemotherapy in liposarcoma.

Plos One

Guo, Shang S; Lopez-Marquez, Hector H; Fan, Kenneth C KC; Choy, Edwin E; Cote, Gregory G; Harmon, David D; Nielsen, G Petur GP; Yang, Cao C; Zhang, Changqing C; Mankin, Henry H; Hornicek, Francis J FJ; Borger, Darrell R DR; Duan, Zhenfeng Z

Publication Date: 2014

Variant appearance in text: NRAS: p110a

PubMed Link: 24695632

Variant Present in the following documents:

• pone.0093996.pdf

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Novel somatic mutations to PI3K pathway genes in metastatic melanoma.

Plos One

Shull, Austin Y AY; Latham-Schwark, Alicia A; Ramasamy, Poornema P; Leskoske, Kristin K; Oroian, Dora D; Birtwistle, Marc R MR; Buckhaults, Phillip J PJ

Publication Date: 2012

Variant appearance in text: NRAS: p110a

PubMed Link: 22912864

Variant Present in the following documents:

• pone.0043369.pdf

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Melanoma: from mutations to medicine.

Genes & Development

Tsao, Hensin H; Chin, Lynda L; Garraway, Levi A LA; Fisher, David E DE

Publication Date: 2012-06-01

Variant appearance in text: NRAS: p110a

PubMed Link: 22661227

Variant Present in the following documents:

• Main text

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PIK3CA mutations frequently coexist with RAS and BRAF mutations in patients with advanced cancers.

Plos One

Janku, Filip F; Lee, J Jack JJ; Tsimberidou, Apostolia M AM; Hong, David S DS; Naing, Aung A; Falchook, Gerald S GS; Fu, Siqing S; Luthra, Rajyalakshmi R; Garrido-Laguna, Ignacio I; Kurzrock, Razelle R

Publication Date: 2011

Variant appearance in text: NRAS: p110a

PubMed Link: 21829508

Variant Present in the following documents:

• pone.0022769.pdf

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Dissection of RAS downstream pathways in melanomagenesis: a role for Ral in transformation.

Oncogene

Mishra, P J PJ; Ha, L L; Rieker, J J; Sviderskaya, E V EV; Bennett, D C DC; Oberst, M D MD; Kelly, K K; Merlino, G G

Publication Date: 2010-04-22

Variant appearance in text: NRAS: p110a

PubMed Link: 20118982

Variant Present in the following documents:

• Main text

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A novel AKT3 mutation in melanoma tumours and cell lines.

British Journal Of Cancer

Davies, M A MA; Stemke-Hale, K K; Tellez, C C; Calderone, T L TL; Deng, W W; Prieto, V G VG; Lazar, A J F AJ; Gershenwald, J E JE; Mills, G B GB

Publication Date: 2008-10-21

Variant appearance in text: NRAS: p110a

PubMed Link: 18813315

Variant Present in the following documents:

• 6604637a.pdf

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