Publications:

mTOR Signaling and SREBP Activity Increase FADS2 Expression and Can Activate Sapienate Biosynthesis.

Cell Reports

Triki, Mouna M; Rinaldi, Gianmarco G; Planque, Melanie M; Broekaert, Dorien D; Winkelkotte, Alina M AM; Maier, Carina R CR; Janaki Raman, Sudha S; Vandekeere, Anke A; Van Elsen, Joke J; Orth, Martin F MF; Grünewald, Thomas G P TGP; Schulze, Almut A; Fendt, Sarah-Maria SM

Publication Date: 2020-06-23

Variant appearance in text: NRAS: D69E

PubMed Link: 32579932

Variant Present in the following documents:

• mmc5.xlsx, sheet 3

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Mapping phospho-catalytic dependencies of therapy-resistant tumours reveals actionable vulnerabilities.

Nature Cell Biology

Coppé, Jean-Philippe JP; Mori, Miki M; Pan, Bo B; Yau, Christina C; Wolf, Denise M DM; Ruiz-Saenz, Ana A; Brunen, Diede D; Prahallad, Anirudh A; Cornelissen-Steijger, Paulien P; Kemper, Kristel K; Posch, Christian C; Wang, Changjun C; Dreyer, Courtney A CA; Krijgsman, Oscar O; Lee, Pei Rong Evelyn PRE; Chen, Zhongzhong Z; Peeper, Daniel S DS; Moasser, Mark M MM; Bernards, René R; van 't Veer, Laura J LJ

Publication Date: 2019-06

Variant appearance in text: NRAS: D69E

PubMed Link: 31160710

Variant Present in the following documents:

• Main text

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appreci8: a pipeline for precise variant calling integrating 8 tools.

Bioinformatics (Oxford, England)

Sandmann, Sarah S; Karimi, Mohsen M; de Graaf, Aniek O AO; Rohde, Christian C; Göllner, Stefanie S; Varghese, Julian J; Ernsting, Jan J; Walldin, Gunilla G; van der Reijden, Bert A BA; Müller-Tidow, Carsten C; Malcovati, Luca L; Hellström-Lindberg, Eva E; Jansen, Joop H JH; Dugas, Martin M

Publication Date: 2018-12-15

Variant appearance in text: NRAS: 207C>A; Asp69Glu

PubMed Link: 29945233

Variant Present in the following documents:

• bty518_supplementary_data_s3.xlsx, sheet 9
• bty518_supplementary_data_s4.xlsx, sheet 8
• bty518_supplementary_data_s4.xlsx, sheet 9

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Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One

Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS

Publication Date: 2018

Variant appearance in text: NRAS: D69E

PubMed Link: 29698444

Variant Present in the following documents:

• pone.0196434.s001.xlsx, sheet 1
• pone.0196434.s001.xlsx, sheet 2

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Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications

Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ

Publication Date: 2017-05-11

Variant appearance in text: N-ras: 207C>A

PubMed Link: 28492226

Variant Present in the following documents:

• ncomms15086-s3.xlsx, sheet 1

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