NRAS c.181C>T ;(p.Q61*)

Variant ID: 1-115256530-G-A

NM_002524.4(NRAS):c.181C>T;(p.Q61*)

This variant was identified in 45 publications

View GRCh38 version.




Publications:


The Complex Cyto-Molecular Landscape of Thyroid Nodules in Pediatrics.

Cancers
Seminati, Davide D; Ceola, Stefano S; Pincelli, Angela Ida AI; Leni, Davide D; Gatti, Andrea A; Garancini, Mattia M; L'Imperio, Vincenzo V; Cattoni, Alessandro A; Pagni, Fabio F
Publication Date: 2023-03-29

Variant appearance in text: NRAS: Q61X
PubMed Link: 37046700
Variant Present in the following documents:
  • Main text
  • cancers-15-02039.pdf
View BVdb publication page



Recapitulating thyroid cancer histotypes through engineering embryonic stem cells.

Nature Communications
Veschi, Veronica V; Turdo, Alice A; Modica, Chiara C; Verona, Francesco F; Di Franco, Simone S; Gaggianesi, Miriam M; Tirrò, Elena E; Di Bella, Sebastiano S; Iacono, Melania Lo ML; Pantina, Vincenzo Davide VD; Porcelli, Gaetana G; Mangiapane, Laura Rosa LR; Bianca, Paola P; Rizzo, Aroldo A; Sciacca, Elisabetta E; Pillitteri, Irene I; Vella, Veronica V; Belfiore, Antonino A; Bongiorno, Maria Rita MR; Pistone, Giuseppe G; Memeo, Lorenzo L; Colarossi, Lorenzo L; Giuffrida, Dario D; Colarossi, Cristina C; Vigneri, Paolo P; Todaro, Matilde M; Stassi, Giorgio G
Publication Date: 2023-03-11

Variant appearance in text: N/A
PubMed Link: 36906579
Variant Present in the following documents:
View BVdb publication page



Targeted therapies for KRAS-mutant non-small cell lung cancer: from preclinical studies to clinical development-a narrative review.

Translational Lung Cancer Research
Santarpia, Mariacarmela M; Ciappina, Giuliana G; Spagnolo, Calogera Claudia CC; Squeri, Andrea A; Passalacqua, Maria Ilenia MI; Aguilar, Andrés A; Gonzalez-Cao, Maria M; Giovannetti, Elisa E; Silvestris, Nicola N; Rosell, Rafael R
Publication Date: 2023-02-28

Variant appearance in text: NRAS: Q61X
PubMed Link: 36895930
Variant Present in the following documents:
  • Main text
  • tlcr-12-02-346.pdf
View BVdb publication page



High-risk multiple myeloma predicted by circulating plasma cells and its genetic characteristics.

Frontiers In Oncology
Xia, Yuan Y; Shen, Na N; Zhang, Run R; Wu, Yujie Y; Shi, Qinglin Q; Li, Jianyong J; Chen, Lijuan L; Xu, Min M; Jin, Yuanyuan Y
Publication Date: 2023

Variant appearance in text: rs121913254
PubMed Link: 36845679
Variant Present in the following documents:
  • Table_1.xlsx, sheet 2
View BVdb publication page



Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics
Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P
Publication Date: 2023-02-23

Variant appearance in text: NRAS: 181C>T; Gln61Ter
PubMed Link: 36823319
Variant Present in the following documents:
  • 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6
View BVdb publication page



Integrative genomic analysis of childhood acute lymphoblastic leukaemia lacking a genetic biomarker in the UKALL2003 clinical trial.

Leukemia
Schwab, Claire C; Cranston, Ruth E RE; Ryan, Sarra L SL; Butler, Ellie E; Winterman, Emily E; Hawking, Zoe Z; Bashton, Matthew M; Enshaei, Amir A; Russell, Lisa J LJ; Kingsbury, Zoya Z; Peden, John F JF; Barretta, Emilio E; Murray, James J; Gibson, Jude J; Hinchliffe, Andrew C AC; Bain, Robert R; Vora, Ajay A; Bentley, David R DR; Ross, Mark T MT; Moorman, Anthony V AV; Harrison, Christine J CJ
Publication Date: 2022-12-22

Variant appearance in text: NRAS: Q61X
PubMed Link: 36550215
Variant Present in the following documents:
  • 41375_2022_1799_MOESM1_ESM.pdf
View BVdb publication page



Genomic landscape of the immunogenicity regulation in skin melanomas with diverse tumor mutation burden.

Frontiers In Immunology
Georgoulias, George G; Zaravinos, Apostolos A
Publication Date: 2022

Variant appearance in text: NRAS: Q61*
PubMed Link: 36389735
Variant Present in the following documents:
  • Table_7.xlsx, sheet 9
View BVdb publication page



A comparison of DNA sequencing and gene expression profiling to assist tissue of origin diagnosis in cancer of unknown primary.

The Journal Of Pathology
Posner, Atara A; Prall, Owen Wj OW; Sivakumaran, Tharani T; Etemadamoghadam, Dariush D; Thio, Niko N; Pattison, Andrew A; Balachander, Shiva S; Fisher, Krista K; Webb, Samantha S; Wood, Colin C; DeFazio, Anna A; Wilcken, Nicholas N; Gao, Bo B; Karapetis, Christos S CS; Singh, Madhu M; Collins, Ian M IM; Richardson, Gary G; Steer, Christopher C; Warren, Mark M; Karanth, Narayan N; Wright, Gavin G; Williams, Scott S; George, Joshy J; Hicks, Rodney J RJ; Boussioutas, Alex A; Gill, Anthony J AJ; Solomon, Benjamin J BJ; Xu, Huiling H; Fellowes, Andrew A; Fox, Stephen B SB; Schofield, Penelope P; Bowtell, David D; Mileshkin, Linda L; Tothill, Richard W RW
Publication Date: 2022-10-26

Variant appearance in text: NRAS: Gln61Ter
PubMed Link: 36287571
Variant Present in the following documents:
  • PATH-259-81-s011.xlsx, sheet 2
View BVdb publication page



Effects of Noonan Syndrome-Germline Mutations on Mitochondria and Energy Metabolism.

Cells
Bajia, Donald D; Bottani, Emanuela E; Derwich, Katarzyna K
Publication Date: 2022-10-01

Variant appearance in text: NRAS: Q61X
PubMed Link: 36231062
Variant Present in the following documents:
  • cells-11-03099.pdf
View BVdb publication page



Prevalence of Molecular Alterations in a Swiss Cohort of 512 Colorectal Carcinoma Patients by Targeted Next-Generation Sequencing Analysis in Routine Diagnostics.

Pathobiology : Journal Of Immunopathology, Molecular And Cellular Biology
Haefliger, Simon S; Marston, Katharina K; Alborelli, Ilaria I; Stauffer, Edouard-Jean EJ; Gugger, Mathias M; Jermann, Philip M PM; Hoeller, Sylvia S; Tornillo, Luigi L; Terracciano, Luigi M LM; Bihl, Michel M; Matter, Matthias S MS
Publication Date: 2022-10-06

Variant appearance in text: NRAS: Q61*
PubMed Link: 36202073
Variant Present in the following documents:
  • pat-0090-0166-s01.pdf
View BVdb publication page



TLS/FUS-ERG fusion gene in acute leukemia and myelodysplastic syndrome evolved to acute leukemia: report of six cases and a literature review.

Annals Of Hematology
Zhang, Heyang H; Zhan, Qianru Q; Wang, Xiaoxue X; Gao, Feng F; Yu, Jinxiang J; Wang, Jing J; Fu, Wei W; Wang, Pingping P; Wei, Xin X; Zhang, Lijun L
Publication Date: 2022-12

Variant appearance in text: rs121913254
PubMed Link: 36181538
Variant Present in the following documents:
  • Main text
  • 277_2022_Article_4979.pdf
View BVdb publication page



Perspectives in Melanoma: meeting report from the Melanoma Bridge (December 2nd - 4th, 2021, Italy).

Journal Of Translational Medicine
Ascierto, Paolo A PA; Agarwala, Sanjiv S SS; Blank, Christian C; Caracò, Corrado C; Carvajal, Richard D RD; Ernstoff, Marc S MS; Ferrone, Soldano S; Fox, Bernard A BA; Gajewski, Thomas F TF; Garbe, Claus C; Grob, Jean-Jacques JJ; Hamid, Omid O; Krogsgaard, Michelle M; Lo, Roger S RS; Lund, Amanda W AW; Madonna, Gabriele G; Michielin, Olivier O; Neyns, Bart B; Osman, Iman I; Peters, Solange S; Poulikakos, Poulikos I PI; Quezada, Sergio A SA; Reinfeld, Bradley B; Zitvogel, Laurence L; Puzanov, Igor I; Thurin, Magdalena M
Publication Date: 2022-09-04

Variant appearance in text: NRAS: Q61X
PubMed Link: 36058945
Variant Present in the following documents:
  • Main text
  • 12967_2022_Article_3592.pdf
View BVdb publication page



Evolution of intra-tumoral heterogeneity across different pathological stages in papillary thyroid carcinoma.

Cancer Cell International
Affinito, Ornella O; Orlandella, Francesca Maria FM; Luciano, Neila N; Salvatore, Marco M; Salvatore, Giuliana G; Franzese, Monica M
Publication Date: 2022-08-22

Variant appearance in text: rs121913254
PubMed Link: 35996174
Variant Present in the following documents:
  • 12935_2022_2680_MOESM5_ESM.xlsx, sheet 5
View BVdb publication page



Genomic Landscape of RTK/RAS Pathway and Tumor Immune Infiltration as Prognostic Indicator of Lung Adenocarcinoma.

Frontiers In Oncology
Yin, Xiang-Qian XQ; Yin, Xue-Hui XH; Yu, Ya-Qin YQ; Xu, Lang L; Zhang, Mao M
Publication Date: 2022

Variant appearance in text: rs121913254
PubMed Link: 35936718
Variant Present in the following documents:
  • Table_4.xlsx, sheet 2
View BVdb publication page



Genome-wide analyses of 200,453 individuals yield new insights into the causes and consequences of clonal hematopoiesis.

Nature Genetics
Kar, Siddhartha P SP; Quiros, Pedro M PM; Gu, Muxin M; Jiang, Tao T; Mitchell, Jonathan J; Langdon, Ryan R; Iyer, Vivek V; Barcena, Clea C; Vijayabaskar, M S MS; Fabre, Margarete A MA; Carter, Paul P; Petrovski, Slavé S; Burgess, Stephen S; Vassiliou, George S GS
Publication Date: 2022-08

Variant appearance in text: NRAS: Q61*
PubMed Link: 35835912
Variant Present in the following documents:
  • 41588_2022_1121_MOESM3_ESM.xlsx, sheet 4
View BVdb publication page



Inactivation of the Hippo tumor suppressor pathway promotes melanoma.

Nature Communications
Vittoria, Marc A MA; Kingston, Nathan N; Kotynkova, Kristyna K; Xia, Eric E; Hong, Rui R; Huang, Lee L; McDonald, Shayna S; Tilston-Lunel, Andrew A; Darp, Revati R; Campbell, Joshua D JD; Lang, Deborah D; Xu, Xiaowei X; Ceol, Craig J CJ; Varelas, Xaralabos X; Ganem, Neil J NJ
Publication Date: 2022-06-29

Variant appearance in text: NRAS: Q61X
PubMed Link: 35768444
Variant Present in the following documents:
  • 41467_2022_31399_MOESM1_ESM.pdf
View BVdb publication page



Systematic review and meta-analysis of genomic alterations in acral melanoma.

Pigment Cell & Melanoma Research
Broit, Natasa N; Johansson, Peter A PA; Rodgers, Chloe B CB; Walpole, Sebastian T ST; Hayward, Nicholas K NK; Pritchard, Antonia L AL
Publication Date: 2022-05

Variant appearance in text: rs121913254
PubMed Link: 35229492
Variant Present in the following documents:
  • PCMR-35-369-s003.xlsx, sheet 6
View BVdb publication page



Cytoskeletal Remodelling as an Achilles' Heel for Therapy Resistance in Melanoma.

Cells
Barreno, Adrian A; Orgaz, Jose L JL
Publication Date: 2022-02-02

Variant appearance in text: NRAS: Q61X
PubMed Link: 35159327
Variant Present in the following documents:
  • Main text
View BVdb publication page



Cytoskeletal Remodelling as an Achilles' Heel for Therapy Resistance in Melanoma.

Cells
Barreno, Adrian A; Orgaz, Jose L JL
Publication Date: 2022-02-02

Variant appearance in text: NRAS: Q61X
PubMed Link: 35159327
Variant Present in the following documents:
  • Main text
View BVdb publication page



Identification of the nucleotide-free state as a therapeutic vulnerability for inhibition of selected oncogenic RAS mutants.

Cell Reports
Khan, Imran I; Koide, Akiko A; Zuberi, Mariyam M; Ketavarapu, Gayatri G; Denbaum, Eric E; Teng, Kai Wen KW; Rhett, J Matthew JM; Spencer-Smith, Russell R; Hobbs, G Aaron GA; Camp, Ernest Ramsay ER; Koide, Shohei S; O'Bryan, John P JP
Publication Date: 2022-02-08

Variant appearance in text: NRAS: Q61x
PubMed Link: 35139380
Variant Present in the following documents:
  • Main text
  • nihms-1778820.pdf
View BVdb publication page



KLF3 and PAX6 are candidate driver genes in late-stage, MSI-hypermutated endometrioid endometrial carcinomas.

Plos One
Rudd, Meghan L ML; Hansen, Nancy F NF; Zhang, Xiaolu X; Urick, Mary Ellen ME; Zhang, Suiyuan S; Merino, Maria J MJ; , ; Mullikin, James C JC; Brody, Lawrence C LC; Bell, Daphne W DW
Publication Date: 2022

Variant appearance in text: rs121913254
PubMed Link: 35081118
Variant Present in the following documents:
  • pone.0251286.s005.xlsx, sheet 8
View BVdb publication page



KLF3 and PAX6 are candidate driver genes in late-stage, MSI-hypermutated endometrioid endometrial carcinomas.

Plos One
Rudd, Meghan L ML; Hansen, Nancy F NF; Zhang, Xiaolu X; Urick, Mary Ellen ME; Zhang, Suiyuan S; Merino, Maria J MJ; , ; Mullikin, James C JC; Brody, Lawrence C LC; Bell, Daphne W DW
Publication Date: 2022

Variant appearance in text: rs121913254
PubMed Link: 35081118
Variant Present in the following documents:
  • pone.0251286.s005.xlsx, sheet 8
View BVdb publication page



Prevalence of targeted therapy-related genetic variations in NSCLC and their relationship with clinicopathological characteristics.

Plos One
Li, Fanghua F; Ye, Peng P; Cai, Peiling P; Dong, Dandan D; Zhang, Yihao Y; Yang, Yue Y; Sun, Xingwang X
Publication Date: 2022

Variant appearance in text: NRAS: Q61X
PubMed Link: 35061839
Variant Present in the following documents:
  • pone.0262822.s002.xlsx, sheet 1
View BVdb publication page



Prevalence of targeted therapy-related genetic variations in NSCLC and their relationship with clinicopathological characteristics.

Plos One
Li, Fanghua F; Ye, Peng P; Cai, Peiling P; Dong, Dandan D; Zhang, Yihao Y; Yang, Yue Y; Sun, Xingwang X
Publication Date: 2022

Variant appearance in text: NRAS: Q61X
PubMed Link: 35061839
Variant Present in the following documents:
  • pone.0262822.s002.xlsx, sheet 1
View BVdb publication page



Recurrent KRAS, KIT and SF3B1 mutations in melanoma of the female genital tract.

Bmc Cancer
Cai, Yuan-Jun YJ; Ke, Long-Feng LF; Zhang, Wen-Wen WW; Lu, Jian-Ping JP; Chen, Yan-Ping YP
Publication Date: 2021-06-08

Variant appearance in text: NRAS: Q61*
PubMed Link: 34102999
Variant Present in the following documents:
  • Main text
  • 12885_2021_Article_8427.pdf
View BVdb publication page



Alternative lengthening of telomeres in childhood neuroblastoma from genome to proteome.

Nature Communications
Hartlieb, Sabine A SA; Sieverling, Lina L; Nadler-Holly, Michal M; Ziehm, Matthias M; Toprak, Umut H UH; Herrmann, Carl C; Ishaque, Naveed N; Okonechnikov, Konstantin K; Gartlgruber, Moritz M; Park, Young-Gyu YG; Wecht, Elisa Maria EM; Savelyeva, Larissa L; Henrich, Kai-Oliver KO; Rosswog, Carolina C; Fischer, Matthias M; Hero, Barbara B; Jones, David T W DTW; Pfaff, Elke E; Witt, Olaf O; Pfister, Stefan M SM; Volckmann, Richard R; Koster, Jan J; Kiesel, Katharina K; Rippe, Karsten K; Taschner-Mandl, Sabine S; Ambros, Peter P; Brors, Benedikt B; Selbach, Matthias M; Feuerbach, Lars L; Westermann, Frank F
Publication Date: 2021-02-24

Variant appearance in text: rs121913254
PubMed Link: 33627664
Variant Present in the following documents:
  • 41467_2021_21247_MOESM10_ESM.xlsx, sheet 1
View BVdb publication page



Molecular correlates and therapeutic targets in T cell-inflamed versus non-T cell-inflamed tumors across cancer types.

Genome Medicine
Bao, Riyue R; Stapor, Daniel D; Luke, Jason J JJ
Publication Date: 2020-10-27

Variant appearance in text: NRAS: Q61*
PubMed Link: 33106165
Variant Present in the following documents:
  • 13073_2020_787_MOESM1_ESM.xlsx, sheet 9
View BVdb publication page



Usefulness of a novel device to divide core needle biopsy specimens in a spatially matched fashion.

Scientific Reports
Shiraishi, Takumi T; Inui, Shogo S; Inoue, Yuta Y; Saito, Yumiko Y; Taga, Hideto H; Kaneko, Masatomo M; Tsuji, Keisuke K; Ueda, Saya S; Ueda, Takashi T; Matsugasumi, Toru T; Taniguchi, Hidefumi H; Ueno, Akihisa A; Yamada, Takeshi T; Yamada, Yasuhiro Y; Iwata, Tsuyoshi T; Fujihara, Atsuko A; Hongo, Fumiya F; Ukimura, Osamu O
Publication Date: 2020-10-13

Variant appearance in text: rs121913254
PubMed Link: 33051506
Variant Present in the following documents:
  • 41598_2020_74136_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Analysis of genetic alterations identifies the frequent mutation of GNAS in colorectal laterally spreading tumors.

Cancer Communications (London, England)
Nong, Yanying Y; Zhang, Yuru Y; Zhang, Yi Y; Pan, Lei L; Chen, Junsheng J; Zhu, Chaojun C; Han, Lu L; Li, Aimin A; Liu, Side S
Publication Date: 2020-11

Variant appearance in text: rs121913254
PubMed Link: 32762003
Variant Present in the following documents:
  • CAC2-40-636-s001.pdf
View BVdb publication page



Epigenomic and genomic analysis of transcriptome modulation in skin cutaneous melanoma.

Aging
Chen, Wuzhen W; Cheng, Pu P; Jiang, Jingxin J; Ren, Yunqing Y; Wu, Dang D; Xue, Dan D
Publication Date: 2020-07-07

Variant appearance in text: NRAS: 181C>T
PubMed Link: 32639949
Variant Present in the following documents:
  • aging-12-103115-s013..xlsx, sheet 1
View BVdb publication page



Mutational concordance between primary and metastatic melanoma: a next-generation sequencing approach.

Journal Of Translational Medicine
Manca, Antonella A; Paliogiannis, Panagiotis P; Colombino, Maria M; Casula, Milena M; Lissia, Amelia A; Botti, Gerardo G; Caracò, Corrado C; Ascierto, Paolo A PA; Sini, Maria Cristina MC; Palomba, Grazia G; Pisano, Marina M; , ; , ; Doneddu, Valentina V; Cossu, Antonio A; Palmieri, Giuseppe G; ,
Publication Date: 2019-08-28

Variant appearance in text: rs121913254
PubMed Link: 31455347
Variant Present in the following documents:
  • 12967_2019_2039_MOESM1_ESM.xlsx, sheet 2
View BVdb publication page



Prospective evaluation of two screening methods for molecular testing of metastatic melanoma: Diagnostic performance of BRAF V600E immunohistochemistry and of a NRAS-BRAF fully automated real-time PCR-based assay.

Plos One
Vallée, Audrey A; Denis-Musquer, Marie M; Herbreteau, Guillaume G; Théoleyre, Sandrine S; Bossard, Céline C; Denis, Marc G MG
Publication Date: 2019

Variant appearance in text: NRAS: Q61X
PubMed Link: 31415669
Variant Present in the following documents:
  • Main text
  • pone.0221123.pdf
View BVdb publication page



Relevance and clinicopathologic relationship of BRAF V600E, TERT and NRAS mutations for papillary thyroid carcinoma patients in Northwest China.

Diagnostic Pathology
Huang, Meiling M; Yan, Changjiao C; Xiao, Jingjing J; Wang, Ting T; Ling, Rui R
Publication Date: 2019-07-12

Variant appearance in text: NRAS: Q61X
PubMed Link: 31300059
Variant Present in the following documents:
  • Main text
  • 13000_2019_Article_849.pdf
View BVdb publication page



Next-generation sequencing of circulating tumor DNA for detection of gene mutations in lung cancer: implications for precision treatment.

Oncotargets And Therapy
Lai, Jinhuo J; Du, Bin B; Wang, Yao Y; Wu, Riping R; Yu, Zongyang Z
Publication Date: 2018

Variant appearance in text: NRAS: 181C>T; Q61*
PubMed Link: 30588023
Variant Present in the following documents:
  • Main text
View BVdb publication page



Whole-exon sequencing of human myeloma cell lines shows mutations related to myeloma patients at relapse with major hits in the DNA regulation and repair pathways.

Journal Of Hematology & Oncology
Tessoulin, Benoît B; Moreau-Aubry, Agnès A; Descamps, Géraldine G; Gomez-Bougie, Patricia P; Maïga, Sophie S; Gaignard, Alban A; Chiron, David D; Ménoret, Emmanuelle E; Le Gouill, Steven S; Moreau, Philippe P; Amiot, Martine M; Pellat-Deceunynck, Catherine C
Publication Date: 2018-12-13

Variant appearance in text: rs121913254
PubMed Link: 30545397
Variant Present in the following documents:
  • 13045_2018_679_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: NRAS: Q61*
PubMed Link: 29698444
Variant Present in the following documents:
  • pone.0196434.s001.xlsx, sheet 3
  • pone.0196434.s001.xlsx, sheet 2
View BVdb publication page



Discovery of coding regions in the human genome by integrated proteogenomics analysis workflow.

Nature Communications
Zhu, Yafeng Y; Orre, Lukas M LM; Johansson, Henrik J HJ; Huss, Mikael M; Boekel, Jorrit J; Vesterlund, Mattias M; Fernandez-Woodbridge, Alejandro A; Branca, Rui M M RMM; Lehtiö, Janne J
Publication Date: 2018-03-02

Variant appearance in text: rs121913254
PubMed Link: 29500430
Variant Present in the following documents:
  • 41467_2018_3311_MOESM5_ESM.xlsx, sheet 1
View BVdb publication page



Chromothripsis 18 in multiple myeloma patient with rapid extramedullary relapse.

Molecular Cytogenetics
Smetana, Jan J; Oppelt, Jan J; Štork, Martin M; Pour, Luděk L; Kuglík, Petr P
Publication Date: 2018

Variant appearance in text: rs121913254
PubMed Link: 29375670
Variant Present in the following documents:
  • 13039_2018_357_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Comprehensive genomic profiling of lung cancer using a validated panel to explore therapeutic targets in East Asian patients.

Cancer Science
Liu, Liping L; Liu, Jilong J; Shao, Di D; Deng, Qiuhua Q; Tang, Hailing H; Liu, Zu Z; Chen, Xuewei X; Guo, Fengming F; Lin, Yongping Y; Mao, Mao M; Kristiansen, Karsten K; Ye, Mingzhi M; He, Jianxing J
Publication Date: 2017-12

Variant appearance in text: NRAS: Q61X
PubMed Link: 28949084
Variant Present in the following documents:
  • CAS-108-2487.pdf
View BVdb publication page



Pan-urologic cancer genomic subtypes that transcend tissue of origin.

Nature Communications
Chen, Fengju F; Zhang, Yiqun Y; Bossé, Dominick D; Lalani, Aly-Khan A AA; Hakimi, A Ari AA; Hsieh, James J JJ; Choueiri, Toni K TK; Gibbons, Don L DL; Ittmann, Michael M; Creighton, Chad J CJ
Publication Date: 2017-08-04

Variant appearance in text: NRAS: 181C>T
PubMed Link: 28775315
Variant Present in the following documents:
  • 41467_2017_289_MOESM7_ESM.xlsx, sheet 1
View BVdb publication page



Detecting protein variants by mass spectrometry: a comprehensive study in cancer cell-lines.

Genome Medicine
Alfaro, Javier A JA; Ignatchenko, Alexandr A; Ignatchenko, Vladimir V; Sinha, Ankit A; Boutros, Paul C PC; Kislinger, Thomas T
Publication Date: 2017-07-18

Variant appearance in text: rs121913254
PubMed Link: 28716134
Variant Present in the following documents:
  • 13073_2017_454_MOESM6_ESM.xlsx, sheet 1
  • 13073_2017_454_MOESM7_ESM.xlsx, sheet 1
View BVdb publication page



RAF proteins exert both specific and compensatory functions during tumour progression of NRAS-driven melanoma.

Nature Communications
Dorard, Coralie C; Estrada, Charlène C; Barbotin, Céline C; Larcher, Magalie M; Garancher, Alexandra A; Leloup, Jessy J; Beermann, Friedrich F; Baccarini, Manuela M; Pouponnot, Celio C; Larue, Lionel L; Eychène, Alain A; Druillennec, Sabine S
Publication Date: 2017-05-12

Variant appearance in text: NRAS: Q61*
PubMed Link: 28497782
Variant Present in the following documents:
  • ncomms15262-s1.pdf
View BVdb publication page



NF1-mutated melanoma tumors harbor distinct clinical and biological characteristics.

Molecular Oncology
Cirenajwis, Helena H; Lauss, Martin M; Ekedahl, Henrik H; Törngren, Therese T; Kvist, Anders A; Saal, Lao H LH; Olsson, Håkan H; Staaf, Johan J; Carneiro, Ana A; Ingvar, Christian C; Harbst, Katja K; Hayward, Nicholas K NK; Jönsson, Göran G
Publication Date: 2017-04

Variant appearance in text: NRAS: 181C>T; Q61*
PubMed Link: 28267273
Variant Present in the following documents:
  • MOL2-11-438-s003.xls, sheet 1
View BVdb publication page



Genome-wide chemical mutagenesis screens allow unbiased saturation of the cancer genome and identification of drug resistance mutations.

Genome Research
Brammeld, Jonathan S JS; Petljak, Mia M; Martincorena, Inigo I; Williams, Steven P SP; Alonso, Luz Garcia LG; Dalmases, Alba A; Bellosillo, Beatriz B; Robles-Espinoza, Carla Daniela CD; Price, Stacey S; Barthorpe, Syd S; Tarpey, Patrick P; Alifrangis, Constantine C; Bignell, Graham G; Vidal, Joana J; Young, Jamie J; Stebbings, Lucy L; Beal, Kathryn K; Stratton, Michael R MR; Saez-Rodriguez, Julio J; Garnett, Mathew M; Montagut, Clara C; Iorio, Francesco F; McDermott, Ultan U
Publication Date: 2017-04

Variant appearance in text: NRAS: Q61x
PubMed Link: 28179366
Variant Present in the following documents:
  • supp_gr.213546.116_Supplemental_Table_S1.xlsx, sheet 1
View BVdb publication page



A set of defined oncogenic mutation alleles seems to better predict the response to cetuximab in CRC patient-derived xenograft than KRAS 12/13 mutations.

Oncotarget
Chen, Dawei D; Huang, Xuesong X; Cai, Jie J; Guo, Sheng S; Qian, Wubin W; Wery, Jean-Pierre JP; Li, Qi-Xiang QX
Publication Date: 2015-12-01

Variant appearance in text: NRAS: Q61X
PubMed Link: 26512781
Variant Present in the following documents:
  • Main text
View BVdb publication page



Extended RAS and BRAF Mutation Analysis Using Next-Generation Sequencing.

Plos One
Sakai, Kazuko K; Tsurutani, Junji J; Yamanaka, Takeharu T; Yoneshige, Azusa A; Ito, Akihiko A; Togashi, Yosuke Y; De Velasco, Marco A MA; Terashima, Masato M; Fujita, Yoshihiko Y; Tomida, Shuta S; Tamura, Takao T; Nakagawa, Kazuhiko K; Nishio, Kazuto K
Publication Date: 2015

Variant appearance in text: NRAS: Q61*
PubMed Link: 25954997
Variant Present in the following documents:
  • Main text
  • pone.0121891.pdf
View BVdb publication page



Melanoma genome sequencing reveals frequent PREX2 mutations.

Nature
Berger, Michael F MF; Hodis, Eran E; Heffernan, Timothy P TP; Deribe, Yonathan Lissanu YL; Lawrence, Michael S MS; Protopopov, Alexei A; Ivanova, Elena E; Watson, Ian R IR; Nickerson, Elizabeth E; Ghosh, Papia P; Zhang, Hailei H; Zeid, Rhamy R; Ren, Xiaojia X; Cibulskis, Kristian K; Sivachenko, Andrey Y AY; Wagle, Nikhil N; Sucker, Antje A; Sougnez, Carrie C; Onofrio, Robert R; Ambrogio, Lauren L; Auclair, Daniel D; Fennell, Timothy T; Carter, Scott L SL; Drier, Yotam Y; Stojanov, Petar P; Singer, Meredith A MA; Voet, Douglas D; Jing, Rui R; Saksena, Gordon G; Barretina, Jordi J; Ramos, Alex H AH; Pugh, Trevor J TJ; Stransky, Nicolas N; Parkin, Melissa M; Winckler, Wendy W; Mahan, Scott S; Ardlie, Kristin K; Baldwin, Jennifer J; Wargo, Jennifer J; Schadendorf, Dirk D; Meyerson, Matthew M; Gabriel, Stacey B SB; Golub, Todd R TR; Wagner, Stephan N SN; Lander, Eric S ES; Getz, Gad G; Chin, Lynda L; Garraway, Levi A LA
Publication Date: 2012-05-09

Variant appearance in text: rs121913254
PubMed Link: 22622578
Variant Present in the following documents:
  • NIHMS362881-supplement-3.xlsx, sheet 5
View BVdb publication page