NRAS c.179G>T ;(p.G60V)

Variant ID: 1-115256532-C-A

NM_002524.4(NRAS):c.179G>T;(p.G60V)

This variant was identified in 16 publications

View GRCh38 version.




Publications:


Efficacy and clinicogenomic correlates of response to immune checkpoint inhibitors alone or with chemotherapy in non-small cell lung cancer.

Nature Communications
Hong, Lingzhi L; Aminu, Muhammad M; Li, Shenduo S; Lu, Xuetao X; Petranovic, Milena M; Saad, Maliazurina B MB; Chen, Pingjun P; Qin, Kang K; Varghese, Susan S; Rinsurongkawong, Waree W; Rinsurongkawong, Vadeerat V; Spelman, Amy A; Elamin, Yasir Y YY; Negrao, Marcelo V MV; Skoulidis, Ferdinandos F; Gay, Carl M CM; Cascone, Tina T; Gandhi, Saumil J SJ; Lin, Steven H SH; Lee, Percy P PP; Carter, Brett W BW; Wu, Carol C CC; Antonoff, Mara B MB; Sepesi, Boris B; Lewis, Jeff J; Gibbons, Don L DL; Vaporciyan, Ara A AA; Le, Xiuning X; Jack Lee, J J; Roy-Chowdhuri, Sinchita S; Routbort, Mark J MJ; Gainor, Justin F JF; Heymach, John V JV; Lou, Yanyan Y; Wu, Jia J; Zhang, Jianjun J; Vokes, Natalie I NI
Publication Date: 2023-02-08

Variant appearance in text: NRAS: 179G>T; G60V
PubMed Link: 36755027
Variant Present in the following documents:
  • 41467_2023_36328_MOESM6_ESM.xlsx, sheet 1
View BVdb publication page



The clinical utility of integrative genomics in childhood cancer extends beyond targetable mutations.

Nature Cancer
Villani, Anita A; Davidson, Scott S; Kanwar, Nisha N; Lo, Winnie W WW; Li, Yisu Y; Cohen-Gogo, Sarah S; Fuligni, Fabio F; Edward, Lisa-Monique LM; Light, Nicholas N; Layeghifard, Mehdi M; Harripaul, Ricardo R; Waldman, Larissa L; Gallinger, Bailey B; Comitani, Federico F; Brunga, Ledia L; Hayes, Reid R; Anderson, Nathaniel D ND; Ramani, Arun K AK; Yuki, Kyoko E KE; Blay, Sasha S; Johnstone, Brittney B; Inglese, Cara C; Hammad, Rawan R; Goudie, Catherine C; Shuen, Andrew A; Wasserman, Jonathan D JD; Venier, Rosemarie E RE; Eliou, Marianne M; Lorenti, Miranda M; Ryan, Carol Ann CA; Braga, Michael M; Gloven-Brown, Meagan M; Han, Jianan J; Montero, Maria M; Spatare, Famida F; Whitlock, James A JA; Scherer, Stephen W SW; Chun, Kathy K; Somerville, Martin J MJ; Hawkins, Cynthia C; Abdelhaleem, Mohamed M; Ramaswamy, Vijay V; Somers, Gino R GR; Kyriakopoulou, Lianna L; Hitzler, Johann J; Shago, Mary M; Morgenstern, Daniel A DA; Tabori, Uri U; Meyn, Stephen S; Irwin, Meredith S MS; Malkin, David D; Shlien, Adam A
Publication Date: 2022-12-30

Variant appearance in text: NRAS: G60V
PubMed Link: 36585449
Variant Present in the following documents:
  • 43018_2022_474_MOESM12_ESM.xlsx, sheet 6
  • 43018_2022_474_MOESM7_ESM.xlsx, sheet 6
  • 43018_2022_474_MOESM2_ESM.xlsx, sheet 6
  • 43018_2022_474_MOESM3_ESM.xlsx, sheet 6
  • 43018_2022_474_MOESM10_ESM.xlsx, sheet 6
View BVdb publication page



Myelodysplastic Syndrome in a Patient With Common Variable Immunodeficiency: A Rare Occurrence.

Cureus
Mateti, Nihas R NR; Vaddepally, Raju K RK; Skaria, Priya Elsa PE; Chandra, Abhinav B AB
Publication Date: 2022-09

Variant appearance in text: NRAS: G60V
PubMed Link: 36199647
Variant Present in the following documents:
  • Main text
  • cureus-0014-00000028690.pdf
View BVdb publication page



[Allogeneic hematopoietic stem cell transplantation for Familial platelet disorder with a propensity for acute myeloid malignancies with Runx1 germline mutations: a case report and literature review].

Zhonghua Xue Ye Xue Za Zhi = Zhonghua Xueyexue Zazhi
Wang, L L LL; Guan, J J; Cheng, P P; Zhang, T T; Cheng, H H; Zou, L L
Publication Date: 2022-06-14

Variant appearance in text: NRAS: 179G>T; Gly60Val
PubMed Link: 35968597
Variant Present in the following documents:
  • cjh-43-06-517.pdf
View BVdb publication page



Genomic landscape of patients with FLT3-mutated acute myeloid leukemia (AML) treated within the CALGB 10603/RATIFY trial.

Leukemia
Jahn, Nikolaus N; Jahn, Ekaterina E; Saadati, Maral M; Bullinger, Lars L; Larson, Richard A RA; Ottone, Tiziana T; Amadori, Sergio S; Prior, Thomas W TW; Brandwein, Joseph M JM; Appelbaum, Frederick R FR; Medeiros, Bruno C BC; Tallman, Martin S MS; Ehninger, Gerhard G; Heuser, Michael M; Ganser, Arnold A; Pallaud, Celine C; Gathmann, Insa I; Krzykalla, Julia J; Benner, Axel A; Bloomfield, Clara D CD; Thiede, Christian C; Stone, Richard M RM; Döhner, Hartmut H; Döhner, Konstanze K
Publication Date: 2022-09

Variant appearance in text: NRAS: G60V
PubMed Link: 35922444
Variant Present in the following documents:
  • 41375_2022_1650_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Genome-wide analyses of 200,453 individuals yield new insights into the causes and consequences of clonal hematopoiesis.

Nature Genetics
Kar, Siddhartha P SP; Quiros, Pedro M PM; Gu, Muxin M; Jiang, Tao T; Mitchell, Jonathan J; Langdon, Ryan R; Iyer, Vivek V; Barcena, Clea C; Vijayabaskar, M S MS; Fabre, Margarete A MA; Carter, Paul P; Petrovski, Slavé S; Burgess, Stephen S; Vassiliou, George S GS
Publication Date: 2022-08

Variant appearance in text: NRAS: G60V
PubMed Link: 35835912
Variant Present in the following documents:
  • 41588_2022_1121_MOESM3_ESM.xlsx, sheet 4
View BVdb publication page



Pathophysiologic and clinical implications of molecular profiles resultant from deletion 5q.

Ebiomedicine
Adema, Vera V; Palomo, Laura L; Walter, Wencke W; Mallo, Mar M; Hutter, Stephan S; La Framboise, Thomas T; Arenillas, Leonor L; Meggendorfer, Manja M; Radivoyevitch, Tomas T; Xicoy, Blanca B; Pellagatti, Andrea A; Haferlach, Claudia C; Boultwood, Jacqueline J; Kern, Wolfgang W; Visconte, Valeria V; Sekeres, Mikkael M; Barnard, John J; Haferlach, Torsten T; Solé, Francesc F; Maciejewski, Jaroslaw P JP
Publication Date: 2022-06

Variant appearance in text: NRAS: 179G>T; Gly60Val
PubMed Link: 35617825
Variant Present in the following documents:
  • mmc3.xlsx, sheet 1
View BVdb publication page



Anchored Multiplex PCR Custom Melanoma Next Generation Sequencing Panel for Analysis of Circulating Tumor DNA.

Frontiers In Oncology
Diefenbach, Russell J RJ; Lee, Jenny H JH; Stewart, Ashleigh A; Menzies, Alexander M AM; Carlino, Matteo S MS; Saw, Robyn P M RPM; Stretch, Jonathan R JR; Long, Georgina V GV; Scolyer, Richard A RA; Rizos, Helen H
Publication Date: 2022

Variant appearance in text: NRAS: G60V
PubMed Link: 35494035
Variant Present in the following documents:
  • Main text
  • Table_2.xlsx, sheet 1
  • fonc-12-820510.pdf
View BVdb publication page



Effects of NRAS Mutations on Leukemogenesis and Targeting of Children With Acute Lymphoblastic Leukemia.

Frontiers In Cell And Developmental Biology
Qian, Jiabi J; Li, Zifeng Z; Pei, Kunlin K; Li, Ziping Z; Li, Chunjie C; Yan, Muxia M; Qian, Maoxiang M; Song, Yuanbin Y; Zhang, Hui H; He, Yingyi Y
Publication Date: 2022

Variant appearance in text: NRAS: G60V
PubMed Link: 35211470
Variant Present in the following documents:
  • DataSheet2.xlsx, sheet 8
View BVdb publication page



Distinct genetic pathways define pre-malignant versus compensatory clonal hematopoiesis in Shwachman-Diamond syndrome.

Nature Communications
Kennedy, Alyssa L AL; Myers, Kasiani C KC; Bowman, James J; Gibson, Christopher J CJ; Camarda, Nicholas D ND; Furutani, Elissa E; Muscato, Gwen M GM; Klein, Robert H RH; Ballotti, Kaitlyn K; Liu, Shanshan S; Harris, Chad E CE; Galvin, Ashley A; Malsch, Maggie M; Dale, David D; Gansner, John M JM; Nakano, Taizo A TA; Bertuch, Alison A; Vlachos, Adrianna A; Lipton, Jeffrey M JM; Castillo, Paul P; Connelly, James J; Churpek, Jane J; Edwards, John R JR; Hijiya, Nobuko N; Ho, Richard H RH; Hofmann, Inga I; Huang, James N JN; Keel, Siobán S; Lamble, Adam A; Lau, Bonnie W BW; Norkin, Maxim M; Stieglitz, Elliot E; Stock, Wendy W; Walkovich, Kelly K; Boettcher, Steffen S; Brendel, Christian C; Fleming, Mark D MD; Davies, Stella M SM; Weller, Edie A EA; Bahl, Christopher C; Carter, Scott L SL; Shimamura, Akiko A; Lindsley, R Coleman RC
Publication Date: 2021-02-26

Variant appearance in text: NRAS: G60V
PubMed Link: 33637765
Variant Present in the following documents:
  • 41467_2021_21588_MOESM1_ESM.pdf
View BVdb publication page



Resistance of t(17;19)-acute lymphoblastic leukemia cell lines to multiagents in induction therapy.

Cancer Medicine
Watanabe, Atsushi A; Inukai, Takeshi T; Kagami, Keiko K; Abe, Masako M; Takagi, Masatoshi M; Fukushima, Takashi T; Fukushima, Hiroko H; Nanmoku, Toru T; Terui, Kiminori K; Ito, Tatsuya T; Toki, Tsutomu T; Ito, Etsuro E; Fujimura, Junya J; Goto, Hiroaki H; Endo, Mikiya M; Look, Thomas T; Kamps, Mark M; Minegishi, Masayoshi M; Takita, Junko J; Inaba, Toshiya T; Takahashi, Hiroyuki H; Ohara, Akira A; Harama, Daisuke D; Shinohara, Tamao T; Somazu, Shinpei S; Oshiro, Hiroko H; Akahane, Koshi K; Goi, Kumiko K; Sugita, Kanji K
Publication Date: 2019-09

Variant appearance in text: NRAS: G60V
PubMed Link: 31305009
Variant Present in the following documents:
  • Main text
  • CAM4-8-5274.pdf
View BVdb publication page



Resectable lung lesions malignancy assessment and cancer detection by ultra-deep sequencing of targeted gene mutations in plasma cell-free DNA.

Journal Of Medical Genetics
Peng, Muyun M; Xie, Yuancai Y; Li, Xiaohua X; Qian, Youhui Y; Tu, Xiaonian X; Yao, Xumei X; Cheng, Fangsheng F; Xu, Feiyue F; Kong, Deju D; He, Bing B; Liu, Chaoyu C; Cao, Fengjun F; Yang, Haoxian H; Yu, Fenglei F; Xu, Chuanbo C; Tian, Geng G
Publication Date: 2019-10

Variant appearance in text: NRAS: 179G>T; Gly60Val
PubMed Link: 30981987
Variant Present in the following documents:
  • jmedgenet-2018-105825supp002.xlsx, sheet 5
View BVdb publication page



Competitive evolution of NSCLC tumor clones and the drug resistance mechanism of first-generation EGFR-TKIs in Chinese NSCLC patients.

Heliyon
Deng, Qinfang Q; Xie, Boxiong B; Wu, Leilei L; Ji, Xianxiu X; Li, Chao C; Feng, Li L; Fang, Qiyu Q; Bao, Yuchen Y; Li, Jialu J; Jin, Shengnan S; Ding, Chunming C; Li, Yixue Y; Zhou, Songwen S
Publication Date: 2018-12

Variant appearance in text: NRAS: G60V
PubMed Link: 30603682
Variant Present in the following documents:
  • mmc2.xlsx, sheet 1
View BVdb publication page



The evolutionary landscape of colorectal tumorigenesis.

Nature Ecology & Evolution
Cross, William W; Kovac, Michal M; Mustonen, Ville V; Temko, Daniel D; Davis, Hayley H; Baker, Ann-Marie AM; Biswas, Sujata S; Arnold, Roland R; Chegwidden, Laura L; Gatenbee, Chandler C; Anderson, Alexander R AR; Koelzer, Viktor H VH; Martinez, Pierre P; Jiang, Xiaowei X; Domingo, Enric E; Woodcock, Dan J DJ; Feng, Yun Y; Kovacova, Monika M; Maughan, Tim T; , ; Jansen, Marnix M; Rodriguez-Justo, Manuel M; Ashraf, Shazad S; Guy, Richard R; Cunningham, Christopher C; East, James E JE; Wedge, David C DC; Wang, Lai Mun LM; Palles, Claire C; Heinimann, Karl K; Sottoriva, Andrea A; Leedham, Simon J SJ; Graham, Trevor A TA; Tomlinson, Ian P M IPM
Publication Date: 2018-10

Variant appearance in text: NRAS: G60V
PubMed Link: 30177804
Variant Present in the following documents:
  • Main text
  • emss-78631.pdf
View BVdb publication page



appreci8: a pipeline for precise variant calling integrating 8 tools.

Bioinformatics (Oxford, England)
Sandmann, Sarah S; Karimi, Mohsen M; de Graaf, Aniek O AO; Rohde, Christian C; Göllner, Stefanie S; Varghese, Julian J; Ernsting, Jan J; Walldin, Gunilla G; van der Reijden, Bert A BA; Müller-Tidow, Carsten C; Malcovati, Luca L; Hellström-Lindberg, Eva E; Jansen, Joop H JH; Dugas, Martin M
Publication Date: 2018-12-15

Variant appearance in text: NRAS: 179G>T; Gly60Val
PubMed Link: 29945233
Variant Present in the following documents:
  • bty518_supplementary_data_s4.xlsx, sheet 8
View BVdb publication page



Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications
Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ
Publication Date: 2017-05-11

Variant appearance in text: N-ras: 179G>T
PubMed Link: 28492226
Variant Present in the following documents:
  • ncomms15086-s3.xlsx, sheet 1
View BVdb publication page