Oncogenic RAS commandeers amino acid sensing machinery to aberrantly activate mTORC1 in multiple myeloma.
Nature Communications
Yang, Yandan Y; Bolomsky, Arnold A; Oellerich, Thomas T; Chen, Ping P; Ceribelli, Michele M; Häupl, Björn B; Wright, George W GW; Phelan, James D JD; Huang, Da Wei DW; Lord, James W JW; Van Winkle, Callie K CK; Yu, Xin X; Wisniewski, Jan J; Wang, James Q JQ; Tosto, Frances A FA; Beck, Erin E; Wilson, Kelli K; McKnight, Crystal C; Travers, Jameson J; Klumpp-Thomas, Carleen C; Smith, Grace A GA; Pittaluga, Stefania S; Maric, Irina I; Kazandjian, Dickran D; Thomas, Craig J CJ; Young, Ryan M RM
A pilot study of the use of dynamic analysis of cell-free DNA from aqueous humor and vitreous fluid for the diagnosis and treatment monitoring of vitreoretinal lymphomas.
Haematologica
Wang, Xiaoxiao X; Su, Wenru W; Gao, Yan Y; Feng, Yanfen Y; Wang, Xiaoxia X; Chen, Xiaoqing X; Hu, Yunwei Y; Ma, Yutong Y; Ou, Qiuxiang Q; Liang, Dan D; Huang, Huiqiang H
Multiclonal complexity of pediatric acute lymphoblastic leukemia and the prognostic relevance of subclonal mutations
Haematologica
Antić, Željko Ž; Yu, Jiangyan J; Van Reijmersdal, Simon V SV; Van Dijk, Anke A; Dekker, Linde L; Segerink, Wouter H WH; Sonneveld, Edwin E; Fiocco, Marta M; Pieters, Rob R; Hoogerbrugge, Peter M PM; Van Leeuwen, Frank N FN; Van Kessel, Ad Geurts AG; Waanders, Esme E; Kuiper, Roland P RP
Multiclonal complexity of pediatric acute lymphoblastic leukemia and the prognostic relevance of subclonal mutations
Haematologica
Antić, Željko Ž; Yu, Jiangyan J; Van Reijmersdal, Simon V SV; Van Dijk, Anke A; Dekker, Linde L; Segerink, Wouter H WH; Sonneveld, Edwin E; Fiocco, Marta M; Pieters, Rob R; Hoogerbrugge, Peter M PM; Van Leeuwen, Frank N FN; Van Kessel, Ad Geurts AG; Waanders, Esme E; Kuiper, Roland P RP
Activating KRAS, NRAS, and BRAF mutants enhance proteasome capacity and reduce endoplasmic reticulum stress in multiple myeloma.
Proceedings Of The National Academy Of Sciences Of The United States Of America
Shirazi, Fazal F; Jones, Richard J RJ; Singh, Ram K RK; Zou, Jianxuan J; Kuiatse, Isere I; Berkova, Zuzana Z; Wang, Hua H; Lee, Hans C HC; Hong, Samuel S; Dick, Larry L; Chattopadhyay, Nibedita N; Orlowski, Robert Z RZ
Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.
Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Mutational analysis of pulmonary tumours with neuroendocrine features using targeted massive parallel sequencing: a comparison of a neglected tumour group.
British Journal Of Cancer
Vollbrecht, Claudia C; Werner, Robert R; Walter, Robert Fred Henry RF; Christoph, Daniel Christian DC; Heukamp, Lukas Carl LC; Peifer, Martin M; Hirsch, Burkhard B; Burbat, Lina L; Mairinger, Thomas T; Schmid, Kurt Werner KW; Wohlschlaeger, Jeremias J; Mairinger, Fabian Dominik FD