NRAS c.35G>C ;(p.G12A)

Variant ID: 1-115258747-C-G

NM_002524.4(NRAS):c.35G>C;(p.G12A)

This variant was identified in 235 publications

View GRCh38 version.




Publications:


Recent Advancements, Limitations, and Future Perspectives of the use of Personalized Medicine in Treatment of Colon Cancer.

Technology In Cancer Research & Treatment
Dey, Amit A; Mitra, Abhijit A; Pathak, Surajit S; Prasad, Suhanya S; Zhang, Alexander Sun AS; Zhang, Hong H; Sun, Xiao-Feng XF; Banerjee, Antara A
Publication Date: 2023

Variant appearance in text: NRAS: G12A
PubMed Link: 37248615
Variant Present in the following documents:
  • 10.1177_15330338231178403.pdf
View BVdb publication page



Molecular profiling of colorectal cancer in a genetically admixed Hispanic population.

Cancer Medicine
Montes-Rodríguez, Ingrid M IM; Centeno-Girona, Hilmaris H; Rivera-Lynch, Camila C; Rivera, Noridza N; Cruz-Correa, Marcia M
Publication Date: 2023-04-11

Variant appearance in text: NRAS: G12A
PubMed Link: 37039257
Variant Present in the following documents:
  • CAM4-12-11686-s002.xlsx, sheet 1
View BVdb publication page



Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.

Nature Communications
Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA
Publication Date: 2023-04-03

Variant appearance in text: NRAS: G12A
PubMed Link: 37012232
Variant Present in the following documents:
  • 41467_2023_37547_MOESM12_ESM.xlsx, sheet 2
View BVdb publication page



Somatic mutation detection and KRAS amplification in testicular germ cell tumors.

Frontiers In Oncology
Cabral, Eduardo R M ERM; Pacanhella, Marilia F MF; Lengert, Andre V H AVH; Dos Reis, Mariana B MB; Leal, Leticia F LF; de Lima, Marcos A MA; da Silva, Aline L V ALV; Pinto, Icaro A IA; Reis, Rui M RM; Pinto, Mariana T MT; Cárcano, Flavio M FM
Publication Date: 2023

Variant appearance in text: NRAS: G12A
PubMed Link: 37007070
Variant Present in the following documents:
  • Main text
  • fonc-13-1133363.pdf
View BVdb publication page



Deep genomic characterization highlights complexities and prognostic markers of pediatric acute myeloid leukemia.

Communications Biology
Cheng, Chi-Keung CK; Yung, Yuk-Lin YL; Chan, Hoi-Yun HY; Leung, Kam-Tong KT; Chan, Kathy Y Y KYY; Leung, Alex W K AWK; Cheng, Frankie W T FWT; Li, Chi-Kong CK; Wan, Thomas S K TSK; Luo, Xi X; Pitts, Herbert-Augustus HA; Cheung, Joyce S JS; Chan, Natalie P H NPH; Ng, Margaret H L MHL
Publication Date: 2023-03-31

Variant appearance in text: N/A
PubMed Link: 37002311
Variant Present in the following documents:
View BVdb publication page



Clinical Review of Mucosal Melanoma: The 11-Year Experience of a Referral Center.

Dermatology Practical & Conceptual
Spadafora, Marco M; Santandrea, Giacomo G; Lai, Michela M; Borsari, Stafania S; Kaleci, Shaniko S; Banzi, Chiara C; Mandato, Vincenzo Dario VD; Pellacani, Giovanni G; Piana, Simonetta S; Longo, Caterina C
Publication Date: 2023-01-01

Variant appearance in text: NRAS: G12A
PubMed Link: 36892398
Variant Present in the following documents:
  • 2582dp1301a57.pdf
View BVdb publication page



High-risk multiple myeloma predicted by circulating plasma cells and its genetic characteristics.

Frontiers In Oncology
Xia, Yuan Y; Shen, Na N; Zhang, Run R; Wu, Yujie Y; Shi, Qinglin Q; Li, Jianyong J; Chen, Lijuan L; Xu, Min M; Jin, Yuanyuan Y
Publication Date: 2023

Variant appearance in text: rs121913237
PubMed Link: 36845679
Variant Present in the following documents:
  • Table_1.xlsx, sheet 2
View BVdb publication page



BdLT-Seq as a barcode decay-based method to unravel lineage-linked transcriptome plasticity.

Nature Communications
Shlyakhtina, Yelyzaveta Y; Bloechl, Bianca B; Portal, Maximiliano M MM
Publication Date: 2023-02-25

Variant appearance in text: NRAS: G12A
PubMed Link: 36841849
Variant Present in the following documents:
  • 41467_2023_36744_MOESM1_ESM.pdf
View BVdb publication page



Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics
Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P
Publication Date: 2023-02-23

Variant appearance in text: NRAS: 35G>C; Gly12Ala
PubMed Link: 36823319
Variant Present in the following documents:
  • 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6
View BVdb publication page



Dynamics of age- versus therapy-related clonal hematopoiesis in long-term survivors of pediatric cancer.

Cancer Discovery
Hagiwara, Kohei K; Natarajan, Sivaraman S; Wang, Zhaoming Z; Zubair, Haseeb H; Mulder, Heather L HL; Dong, Li L; Plyler, Emily M EM; Thimmaiah, Padma P; Ma, Xiaotu X; Ness, Kirsten K KK; Li, Zhenghong Z; Mulrooney, Daniel A DA; Wilson, Carmen L CL; Yasui, Yutaka Y; Hudson, Melissa M MM; Easton, John J; Robison, Leslie L LL; Zhang, Jinghui J
Publication Date: 2023-02-08

Variant appearance in text: NRAS: G12A
PubMed Link: 36751942
Variant Present in the following documents:
  • cd-22-0956_tables_s2_s7_s8_s9_suppst1.xlsx, sheet 4
View BVdb publication page



Spectrum and clinical features of gene mutations in Chinese pediatric acute lymphoblastic leukemia.

Bmc Pediatrics
Shen, Diying D; Liu, Lixia L; Xu, Xiaojun X; Song, Hua H; Zhang, Jingying J; Xu, Weiqun W; Zhao, Fenying F; Liang, Juan J; Liao, Chan C; Wang, Yan Y; Xia, Tian T; Wang, Chengcheng C; Lou, Feng F; Cao, Shanbo S; Qin, Jiayue J; Tang, Yongmin Y
Publication Date: 2023-02-04

Variant appearance in text: NRAS: 35G>C
PubMed Link: 36739388
Variant Present in the following documents:
  • 12887_2023_3856_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



DeteX: A highly accurate software for detecting SNV and InDel in single and paired NGS data in cancer research.

Frontiers In Genetics
Cui, Yunlong Y; Li, Hongfeng H; Liu, Pengfei P; Wang, Hailong H; Zhang, Zhenzhen Z; Qu, Hongzhu H; Tian, Caijuan C; Fang, Xiangdong X
Publication Date: 2022

Variant appearance in text: NRAS: 35G>C; Gly12Ala
PubMed Link: 36685970
Variant Present in the following documents:
  • Table5.xlsx, sheet 1
View BVdb publication page



The clinical utility of integrative genomics in childhood cancer extends beyond targetable mutations.

Nature Cancer
Villani, Anita A; Davidson, Scott S; Kanwar, Nisha N; Lo, Winnie W WW; Li, Yisu Y; Cohen-Gogo, Sarah S; Fuligni, Fabio F; Edward, Lisa-Monique LM; Light, Nicholas N; Layeghifard, Mehdi M; Harripaul, Ricardo R; Waldman, Larissa L; Gallinger, Bailey B; Comitani, Federico F; Brunga, Ledia L; Hayes, Reid R; Anderson, Nathaniel D ND; Ramani, Arun K AK; Yuki, Kyoko E KE; Blay, Sasha S; Johnstone, Brittney B; Inglese, Cara C; Hammad, Rawan R; Goudie, Catherine C; Shuen, Andrew A; Wasserman, Jonathan D JD; Venier, Rosemarie E RE; Eliou, Marianne M; Lorenti, Miranda M; Ryan, Carol Ann CA; Braga, Michael M; Gloven-Brown, Meagan M; Han, Jianan J; Montero, Maria M; Spatare, Famida F; Whitlock, James A JA; Scherer, Stephen W SW; Chun, Kathy K; Somerville, Martin J MJ; Hawkins, Cynthia C; Abdelhaleem, Mohamed M; Ramaswamy, Vijay V; Somers, Gino R GR; Kyriakopoulou, Lianna L; Hitzler, Johann J; Shago, Mary M; Morgenstern, Daniel A DA; Tabori, Uri U; Meyn, Stephen S; Irwin, Meredith S MS; Malkin, David D; Shlien, Adam A
Publication Date: 2022-12-30

Variant appearance in text: NRAS: G12A
PubMed Link: 36585449
Variant Present in the following documents:
  • 43018_2022_474_MOESM12_ESM.xlsx, sheet 6
  • 43018_2022_474_MOESM7_ESM.xlsx, sheet 6
  • 43018_2022_474_MOESM2_ESM.xlsx, sheet 6
  • 43018_2022_474_MOESM3_ESM.xlsx, sheet 6
  • 43018_2022_474_MOESM10_ESM.xlsx, sheet 6
View BVdb publication page



Identification of Altered Primary Immunodeficiency-Associated Genes and Their Implications in Pediatric Cancers.

Cancers
Standing, Shaelene S; Tran, Son S; Murguia-Favela, Luis L; Kovalchuk, Olga O; Bose, Pinaki P; Narendran, Aru A
Publication Date: 2022-11-30

Variant appearance in text: NRAS: G12A
PubMed Link: 36497424
Variant Present in the following documents:
  • Main text
  • cancers-14-05942.pdf
View BVdb publication page



Patient-derived xenograft models for gastrointestinal tumors: A single-center retrospective study.

Frontiers In Oncology
Yu, Xiongfei X; Chen, Yiran Y; Lu, Jun J; He, Kuifeng K; Chen, Yanyan Y; Ding, Yongfeng Y; Jin, Ketao K; Wang, Haiyong H; Zhang, Haibin H; Wang, Haohao H; Teng, Lisong L
Publication Date: 2022

Variant appearance in text: NRAS: G12A
PubMed Link: 36465411
Variant Present in the following documents:
  • Table_1.xlsx, sheet 5
View BVdb publication page



Role of RAS signaling in ovarian cancer.

F1000Research
Therachiyil, Lubna L; Anand, Anjana A; Azmi, Abdullah A; Bhat, Ajaz A; Korashy, Hesham M HM; Uddin, Shahab S
Publication Date: 2022

Variant appearance in text: NRAS: G12A
PubMed Link: 36451660
Variant Present in the following documents:
  • Main text
  • f1000research-11-138739.pdf
View BVdb publication page



Transcriptome-based molecular subtypes and differentiation hierarchies improve the classification framework of acute myeloid leukemia.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Cheng, Wen-Yan WY; Li, Jian-Feng JF; Zhu, Yong-Mei YM; Lin, Xiang-Jie XJ; Wen, Li-Jun LJ; Zhang, Fan F; Zhang, Yu-Liang YL; Zhao, Ming M; Fang, Hai H; Wang, Sheng-Yue SY; Lin, Xiao-Jing XJ; Qiao, Niu N; Yin, Wei W; Zhang, Jia-Nan JN; Dai, Yu-Ting YT; Jiang, Lu L; Sun, Xiao-Jian XJ; Xu, Yi Y; Zhang, Tong-Tong TT; Chen, Su-Ning SN; Zhu, Hong-Hu HH; Chen, Zhu Z; Jin, Jie J; Wu, De-Pei DP; Shen, Yang Y; Chen, Sai-Juan SJ
Publication Date: 2022-12-06

Variant appearance in text: NRAS: 35G>C; Gly12Ala
PubMed Link: 36442087
Variant Present in the following documents:
  • pnas.2211429119.sd02.xlsx, sheet 1
View BVdb publication page



A sex-informed approach to improve the personalised decision making process in myelodysplastic syndromes: a multicentre, observational cohort study.

The Lancet. Haematology
,
Publication Date: 2022-11-24

Variant appearance in text: NRAS: 35G>C; G12A
PubMed Link: 36436542
Variant Present in the following documents:
  • mmc2.xlsx, sheet 1
View BVdb publication page



Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer.

Nature Communications
Boström, Martin M; Larsson, Erik E
Publication Date: 2022-11-17

Variant appearance in text: NRAS: G12A
PubMed Link: 36396655
Variant Present in the following documents:
  • 41467_2022_34746_MOESM10_ESM.xlsx, sheet 1
View BVdb publication page



Genomic landscape of the immunogenicity regulation in skin melanomas with diverse tumor mutation burden.

Frontiers In Immunology
Georgoulias, George G; Zaravinos, Apostolos A
Publication Date: 2022

Variant appearance in text: NRAS: G12A
PubMed Link: 36389735
Variant Present in the following documents:
  • Table_7.xlsx, sheet 9
View BVdb publication page



Somatic mutations of activating signalling, transcription factor, and tumour suppressor are a precondition for leukaemia transformation in myelodysplastic syndromes.

Journal Of Cellular And Molecular Medicine
Xu, Feng F; Wu, Lin-Yun LY; Guo, Juan J; He, Qi Q; Zhang, Zheng Z; Li, Xiao X
Publication Date: 2022-12

Variant appearance in text: NRAS: G12A
PubMed Link: 36380727
Variant Present in the following documents:
  • Main text
  • JCMM-26-5901.pdf
View BVdb publication page



The kinetics of blast clearance are associated with copy number alterations in childhood B-cell acute lymphoblastic leukemia.

Neoplasia (New York, N.Y.)
Urbańska, Zuzanna Z; Lejman, Monika M; Taha, Joanna J; Madzio, Joanna J; Ostrowska, Kinga K; Miarka-Walczyk, Karolina K; Wypyszczak, Kamila K; Styka, Borys B; Jakubowska, Justyna J; Sędek, Łukasz Ł; Szczepański, Tomasz T; Stańczak, Marcin M; Fendler, Wojciech W; Młynarski, Wojciech W; Pastorczak, Agata A
Publication Date: 2022-10-23

Variant appearance in text: NRAS: Gly12Ala
PubMed Link: 36288679
Variant Present in the following documents:
  • mmc1.pdf
View BVdb publication page



RaScALL: Rapid (Ra) screening (Sc) of RNA-seq data for prognostically significant genomic alterations in acute lymphoblastic leukaemia (ALL).

Plos Genetics
Rehn, Jacqueline J; Mayoh, Chelsea C; Heatley, Susan L SL; McClure, Barbara J BJ; Eadie, Laura N LN; Schutz, Caitlin C; Yeung, David T DT; Cowley, Mark J MJ; Breen, James J; White, Deborah L DL
Publication Date: 2022-10

Variant appearance in text: NRAS: G12A
PubMed Link: 36251721
Variant Present in the following documents:
  • Main text
View BVdb publication page



In Silico Strategies for Designing of Peptide Inhibitors of Oncogenic K-Ras G12V Mutant: Inhibiting Cancer Growth and Proliferation.

Cancers
Ghufran, Mehreen M; Khan, Haider Ali HA; Ullah, Mehran M; Ghufran, Sabreen S; Ayaz, Muhammad M; Siddiq, Muhammad M; Hassan, Syed Shams Ul SSU; Bungau, Simona S
Publication Date: 2022-10-06

Variant appearance in text: NRAS: G12A
PubMed Link: 36230807
Variant Present in the following documents:
  • cancers-14-04884.pdf
View BVdb publication page



Whole-genome analysis identifies novel drivers and high-risk double-hit events in relapsed/refractory myeloma.

Blood
Ansari-Pour, Naser N; Samur, Mehmet K MK; Flynt, Erin E; Gooding, Sarah S; Towfic, Fadi F; Stong, Nicholas N; Ortiz Estevez, Maria M; Mavrommatis, Konstantinos K; Walker, Brian A BA; Morgan, Gareth J GJ; Munshi, Nikhil C NC; Avet Loiseau, Herve H; Thakurta, Anjan A
Publication Date: 2022-10-12

Variant appearance in text: NRAS: G12A
PubMed Link: 36223594
Variant Present in the following documents:
  • BLOOD_BLD-2022-017010-mmc2.xlsx, sheet 1
View BVdb publication page



The mutational landscape of cancer's vulnerability to ionizing radiation.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Gopal, Priyanka P; Yard, Brian D BD; Petty, Aaron A; Lal, Jessica C JC; Bera, Titas K TK; Hoang, Trung Q TQ; Buhimschi, Alexandru B AB; Abazeed, Mohamed E ME
Publication Date: 2022-10-12

Variant appearance in text: NRAS: G12A
PubMed Link: 36222846
Variant Present in the following documents:
  • ccr-22-1914_supplementary_data_2_suppds2.xlsx, sheet 1
View BVdb publication page



Duplex Sequencing Uncovers Recurrent Low-frequency Cancer-associated Mutations in Infant and Childhood KMT2A-rearranged Acute Leukemia.

Hemasphere
Pilheden, Mattias M; Ahlgren, Louise L; Hyrenius-Wittsten, Axel A; Gonzalez-Pena, Veronica V; Sturesson, Helena H; Hansen Marquart, Hanne Vibeke HV; Lausen, Birgitte B; Castor, Anders A; Pronk, Cornelis Jan CJ; Barbany, Gisela G; Pokrovskaja Tamm, Katja K; Fogelstrand, Linda L; Lohi, Olli O; Norén-Nyström, Ulrika U; Asklin, Johanna J; Chen, Yilun Y; Song, Guangchun G; Walsh, Michael M; Ma, Jing J; Zhang, Jinghui J; Saal, Lao H LH; Gawad, Charles C; Hagström-Andersson, Anna K AK
Publication Date: 2022-10

Variant appearance in text: NRAS: G12A
PubMed Link: 36204688
Variant Present in the following documents:
  • hs9-6-e785-s001.xlsx, sheet 6
View BVdb publication page



Comprehensive germline and somatic genomic profiles of Chinese patients with biliary tract cancer.

Frontiers In Oncology
Yu, Haipeng H; Xu, Yan Y; Gao, Wei W; Li, Mei M; He, Ji'an J; Deng, Xiaoqian X; Xing, Wenge W
Publication Date: 2022

Variant appearance in text: NRAS: G12A
PubMed Link: 36072793
Variant Present in the following documents:
  • Table_3.xlsx, sheet 1
View BVdb publication page



NPM1 exon 5 mutations in acute myeloid leukemia: Implications in diagnosis and minimal residual monitoring.

Ejhaem
Wang, Peng P; Segal, Jeremy J; Drazer, Michael W MW; Venkataraman, Girish G; Arber, Daniel A DA; Gurbuxani, Sandeep S
Publication Date: 2022-08

Variant appearance in text: NRAS: G12A
PubMed Link: 36051025
Variant Present in the following documents:
  • Main text
  • JHA2-3-962.pdf
View BVdb publication page



Genomic landscape of patients with FLT3-mutated acute myeloid leukemia (AML) treated within the CALGB 10603/RATIFY trial.

Leukemia
Jahn, Nikolaus N; Jahn, Ekaterina E; Saadati, Maral M; Bullinger, Lars L; Larson, Richard A RA; Ottone, Tiziana T; Amadori, Sergio S; Prior, Thomas W TW; Brandwein, Joseph M JM; Appelbaum, Frederick R FR; Medeiros, Bruno C BC; Tallman, Martin S MS; Ehninger, Gerhard G; Heuser, Michael M; Ganser, Arnold A; Pallaud, Celine C; Gathmann, Insa I; Krzykalla, Julia J; Benner, Axel A; Bloomfield, Clara D CD; Thiede, Christian C; Stone, Richard M RM; Döhner, Hartmut H; Döhner, Konstanze K
Publication Date: 2022-09

Variant appearance in text: NRAS: G12A; rs121913237
PubMed Link: 35922444
Variant Present in the following documents:
  • 41375_2022_1650_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Exploiting gene dependency to inform drug development for multiple myeloma.

Scientific Reports
Went, Molly M; Hoang, Phuc H PH; Law, Philip J PJ; Kaiser, Martin F MF; Houlston, Richard S RS
Publication Date: 2022-07-26

Variant appearance in text: NRAS: G12A
PubMed Link: 35882937
Variant Present in the following documents:
  • 41598_2022_16940_MOESM2_ESM.xlsx, sheet 8
View BVdb publication page



Clonal Evolution at First Sight: A Combined Visualization of Diverse Diagnostic Methods Improves Understanding of Leukemic Progression.

Frontiers In Oncology
Sandmann, Sarah S; Behrens, Yvonne Lisa YL; Davenport, Claudia C; Thol, Felicitas F; Heuser, Michael M; Dörfel, Daniela D; Löhr, Friederike F; Castrup, Agnes A; Steinemann, Doris D; Varghese, Julian J; Schlegelberger, Brigitte B; Dugas, Martin M; Göhring, Gudrun G
Publication Date: 2022

Variant appearance in text: NRAS: 35G>C; Gly12Ala
PubMed Link: 35875134
Variant Present in the following documents:
  • Main text
  • fonc-12-888114.pdf
View BVdb publication page



Genome-wide analyses of 200,453 individuals yield new insights into the causes and consequences of clonal hematopoiesis.

Nature Genetics
Kar, Siddhartha P SP; Quiros, Pedro M PM; Gu, Muxin M; Jiang, Tao T; Mitchell, Jonathan J; Langdon, Ryan R; Iyer, Vivek V; Barcena, Clea C; Vijayabaskar, M S MS; Fabre, Margarete A MA; Carter, Paul P; Petrovski, Slavé S; Burgess, Stephen S; Vassiliou, George S GS
Publication Date: 2022-08

Variant appearance in text: NRAS: G12A
PubMed Link: 35835912
Variant Present in the following documents:
  • 41588_2022_1121_MOESM3_ESM.xlsx, sheet 2
View BVdb publication page



The genetic heterogeneity and drug resistance mechanisms of relapsed refractory multiple myeloma.

Nature Communications
Vo, Josh N JN; Wu, Yi-Mi YM; Mishler, Jeanmarie J; Hall, Sarah S; Mannan, Rahul R; Wang, Lisha L; Ning, Yu Y; Zhou, Jin J; Hopkins, Alexander C AC; Estill, James C JC; Chan, Wallace K B WKB; Yesil, Jennifer J; Cao, Xuhong X; Rao, Arvind A; Tsodikov, Alexander A; Talpaz, Moshe M; Cole, Craig E CE; Ye, Jing C JC; , ; Bergsagel, P Leif PL; Auclair, Daniel D; Cho, Hearn Jay HJ; Robinson, Dan R DR; Chinnaiyan, Arul M AM
Publication Date: 2022-06-29

Variant appearance in text: NRAS: 35G>C; Gly12Ala; rs121913237
PubMed Link: 35768438
Variant Present in the following documents:
  • 41467_2022_31430_MOESM4_ESM.xlsx, sheet 1
View BVdb publication page



Integrated genomic analyses of acral and mucosal melanomas nominate novel driver genes.

Genome Medicine
Wang, Meng M; Banik, Ishani I; Shain, A Hunter AH; Yeh, Iwei I; Bastian, Boris C BC
Publication Date: 2022-06-16

Variant appearance in text: NRAS: G12A
PubMed Link: 35706047
Variant Present in the following documents:
  • 13073_2022_1068_MOESM4_ESM.xlsx, sheet 1
View BVdb publication page



Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma.

Nature Communications
Gounder, Mrinal M MM; Agaram, Narasimhan P NP; Trabucco, Sally E SE; Robinson, Victoria V; Ferraro, Richard A RA; Millis, Sherri Z SZ; Krishnan, Anita A; Lee, Jessica J; Attia, Steven S; Abida, Wassim W; Drilon, Alexander A; Chi, Ping P; Angelo, Sandra P D' SP; Dickson, Mark A MA; Keohan, Mary Lou ML; Kelly, Ciara M CM; Agulnik, Mark M; Chawla, Sant P SP; Choy, Edwin E; Chugh, Rashmi R; Meyer, Christian F CF; Myer, Parvathi A PA; Moore, Jessica L JL; Okimoto, Ross A RA; Pollock, Raphael E RE; Ravi, Vinod V; Singh, Arun S AS; Somaiah, Neeta N; Wagner, Andrew J AJ; Healey, John H JH; Frampton, Garrett M GM; Venstrom, Jeffrey M JM; Ross, Jeffrey S JS; Ladanyi, Marc M; Singer, Samuel S; Brennan, Murray F MF; Schwartz, Gary K GK; Lazar, Alexander J AJ; Thomas, David M DM; Maki, Robert G RG; Tap, William D WD; Ali, Siraj M SM; Jin, Dexter X DX
Publication Date: 2022-06-15

Variant appearance in text: NRAS: G12A
PubMed Link: 35705558
Variant Present in the following documents:
  • 41467_2022_30496_MOESM2_ESM.xls, sheet 1
View BVdb publication page



Rare presentation of multiple thromboses in Erdheim-Chester disease: a case-based review.

International Journal Of Hematology
Liu, Yongchang Y; Huang, Changpin C; Meng, Xiaohu X; Fang, Xin X; Xie, Xupin X; Wang, Changrong C; Wang, Meiyun M
Publication Date: 2022-11

Variant appearance in text: NRAS: G12A
PubMed Link: 35687294
Variant Present in the following documents:
  • Main text
  • 12185_2022_Article_3393.pdf
View BVdb publication page



Clonal evolution after treatment pressure in multiple myeloma: heterogenous genomic aberrations and transcriptomic convergence.

Leukemia
Misund, Kristine K; Hofste Op Bruinink, Davine D; Coward, Eivind E; Hoogenboezem, Remco M RM; Rustad, Even Holth EH; Sanders, Mathijs A MA; Rye, Morten M; Sponaas, Anne-Marit AM; van der Holt, Bronno B; Zweegman, Sonja S; Hovig, Eivind E; Meza-Zepeda, Leonardo A LA; Sundan, Anders A; Myklebost, Ola O; Sonneveld, Pieter P; Waage, Anders A
Publication Date: 2022-07

Variant appearance in text: NRAS: G12A
PubMed Link: 35643867
Variant Present in the following documents:
  • 41375_2022_1597_MOESM3_ESM.xlsx, sheet 7
  • 41375_2022_1597_MOESM4_ESM.xlsx, sheet 1
View BVdb publication page



Pathophysiologic and clinical implications of molecular profiles resultant from deletion 5q.

Ebiomedicine
Adema, Vera V; Palomo, Laura L; Walter, Wencke W; Mallo, Mar M; Hutter, Stephan S; La Framboise, Thomas T; Arenillas, Leonor L; Meggendorfer, Manja M; Radivoyevitch, Tomas T; Xicoy, Blanca B; Pellagatti, Andrea A; Haferlach, Claudia C; Boultwood, Jacqueline J; Kern, Wolfgang W; Visconte, Valeria V; Sekeres, Mikkael M; Barnard, John J; Haferlach, Torsten T; Solé, Francesc F; Maciejewski, Jaroslaw P JP
Publication Date: 2022-06

Variant appearance in text: NRAS: 35G>C; Gly12Ala
PubMed Link: 35617825
Variant Present in the following documents:
  • mmc3.xlsx, sheet 1
View BVdb publication page



Construction and validation of an immunoediting-based optimized neoantigen load (ioTNL) model to predict the response and prognosis of immune checkpoint therapy in various cancers.

Aging
Su, Xiaofan X; Jin, Haoxuan H; Wang, Jiaqian J; Lu, Huiping H; Gu, Tiantian T; Gao, Zhibo Z; Li, Manxiang M
Publication Date: 2022-05-25

Variant appearance in text: NRAS: 35G>C; G12A
PubMed Link: 35613927
Variant Present in the following documents:
  • aging-14-204101-s004.xlsx, sheet 1
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Feasibility and clinical utility of comprehensive genomic profiling of hematological malignancies.

Cancer Science
Fukuhara, Suguru S; Oshikawa-Kumade, Yuji Y; Kogure, Yasunori Y; Shingaki, Sumito S; Kariyazono, Hirokazu H; Kikukawa, Yoshiya Y; Koya, Junji J; Saito, Yuki Y; Tabata, Mariko M; Yoshifuji, Kota K; Mizuno, Kota K; Miyagi-Maeshima, Akiko A; Matsushita, Hiromichi H; Sugiyama, Masanaka M; Ogawa, Chitose C; Inamoto, Yoshihiro Y; Fukuda, Takahiro T; Sugano, Masato M; Yamauchi, Nobuhiko N; Minami, Yosuke Y; Hirata, Makoto M; Yoshida, Teruhiko T; Kohno, Takashi T; Kohsaka, Shinji S; Mano, Hiroyuki H; Shiraishi, Yuichi Y; Ogawa, Seishi S; Izutsu, Koji K; Kataoka, Keisuke K
Publication Date: 2022-08

Variant appearance in text: NRAS: G12A
PubMed Link: 35579198
Variant Present in the following documents:
  • CAS-113-2763-s003.xlsx, sheet 10
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Lenalidomide promotes the development of TP53-mutated therapy-related myeloid neoplasms.

Blood
Sperling, Adam S AS; Guerra, Veronica A VA; Kennedy, James A JA; Yan, Yuanqing Y; Hsu, Joanne I JI; Wang, Feng F; Nguyen, Andrew T AT; Miller, Peter G PG; McConkey, Marie E ME; Quevedo Barrios, Vanessa A VA; Furudate, Ken K; Zhang, Linda L; Kanagal-Shamanna, Rashmi R; Zhang, Jianhua J; Little, Latasha L; Gumbs, Curtis C; Daver, Naval N; DiNardo, Courtney D CD; Kadia, Tapan T; Ravandi, Farhad F; Kantarjian, Hagop H; Garcia-Manero, Guillermo G; Futreal, P Andrew PA; Ebert, Benjamin L BL; Takahashi, Koichi K
Publication Date: 2022-10-20

Variant appearance in text: NRAS: G12A
PubMed Link: 35512188
Variant Present in the following documents:
  • BLOOD_BLD-2021-014956-mmc1.pdf
View BVdb publication page



RUNX1 mutations contribute to the progression of MDS due to disruption of antitumor cellular defense: a study on patients with lower-risk MDS.

Leukemia
Kaisrlikova, Monika M; Vesela, Jitka J; Kundrat, David D; Votavova, Hana H; Dostalova Merkerova, Michaela M; Krejcik, Zdenek Z; Divoky, Vladimir V; Jedlicka, Marek M; Fric, Jan J; Klema, Jiri J; Mikulenkova, Dana D; Stastna Markova, Marketa M; Lauermannova, Marie M; Mertova, Jolana J; Soukupova Maaloufova, Jacqueline J; Jonasova, Anna A; Cermak, Jaroslav J; Belickova, Monika M
Publication Date: 2022-07

Variant appearance in text: NRAS: 35G>C; Gly12Ala
PubMed Link: 35505182
Variant Present in the following documents:
  • 41375_2022_1584_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



RAS activation induces synthetic lethality of MEK inhibition with mitochondrial oxidative metabolism in acute myeloid leukemia.

Leukemia
Decroocq, Justine J; Birsen, Rudy R; Montersino, Camille C; Chaskar, Prasad P; Mano, Jordi J; Poulain, Laury L; Friedrich, Chloe C; Alary, Anne-Sophie AS; Guermouche, Helene H; Sahal, Ambrine A; Fouquet, Guillemette G; Gotanègre, Mathilde M; Simonetta, Federico F; Mouche, Sarah S; Gestraud, Pierre P; Lescure, Auriane A; Del Nery, Elaine E; Bosc, Claudie C; Grenier, Adrien A; Mazed, Fetta F; Mondesir, Johanna J; Chapuis, Nicolas N; Ho, Liza L; Boughalem, Aicha A; Lelorc'h, Marc M; Gobeaux, Camille C; Fontenay, Michaela M; Recher, Christian C; Vey, Norbert N; Guillé, Arnaud A; Birnbaum, Daniel D; Hermine, Olivier O; Radford-Weiss, Isabelle I; Tsantoulis, Petros P; Collette, Yves Y; Castellano, Rémy R; Sarry, Jean-Emmanuel JE; Pasmant, Eric E; Bouscary, Didier D; Kosmider, Olivier O; Tamburini, Jerome J
Publication Date: 2022-05

Variant appearance in text: NRAS: G12A
PubMed Link: 35354920
Variant Present in the following documents:
  • Main text
  • 41375_2022_Article_1541.pdf
View BVdb publication page



Distinct genomic landscape of Chinese pediatric acute myeloid leukemia impacts clinical risk classification.

Nature Communications
Liu, Ting T; Rao, Jianan J; Hu, Wenting W; Cui, Bowen B; Cai, Jiaoyang J; Liu, Yuhan Y; Sun, Huiying H; Chen, Xiaoxiao X; Tang, Yanjing Y; Chen, Jing J; Wang, Xiang X; Wang, Han H; Qian, Wubin W; Mao, Binchen B; Guo, Sheng S; Wang, Ronghua R; Liu, Yu Y; Shen, Shuhong S
Publication Date: 2022-03-28

Variant appearance in text: NRAS: G12A
PubMed Link: 35347147
Variant Present in the following documents:
  • 41467_2022_29336_MOESM7_ESM.xlsx, sheet 1
  • 41467_2022_29336_MOESM8_ESM.xlsx, sheet 1
View BVdb publication page



Custom multi‑tumor next‑generation sequencing panel for routine molecular diagnosis of solid tumors: Validation and results from three‑year clinical use.

International Journal Of Molecular Medicine
Chevrier, Sandy S; Brasselet, Astrid A; Carnet, Marion M; Chevriaux, Angélique A; Gibeaud, Anne A; Jourdain, Marine M; Mananet, Hugo H; Truntzer, Caroline C; Beltjens, Françoise F; Charon-Barra, Céline C; Arnould, Laurent L; Albuisson, Juliette J; Comte, Anthony A; Derangère, Valentin V; Goussot, Vincent V; Boidot, Romain R
Publication Date: 2022-05

Variant appearance in text: NRAS: 35G>C; Gly12Ala
PubMed Link: 35244186
Variant Present in the following documents:
  • Supplementary_Data3.xlsx, sheet 1
View BVdb publication page



Systematic review and meta-analysis of genomic alterations in acral melanoma.

Pigment Cell & Melanoma Research
Broit, Natasa N; Johansson, Peter A PA; Rodgers, Chloe B CB; Walpole, Sebastian T ST; Hayward, Nicholas K NK; Pritchard, Antonia L AL
Publication Date: 2022-05

Variant appearance in text: NRAS: G12A
PubMed Link: 35229492
Variant Present in the following documents:
  • PCMR-35-369-s003.xlsx, sheet 6
  • PCMR-35-369-s003.xlsx, sheet 8
  • PCMR-35-369-s003.xlsx, sheet 12
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Effects of NRAS Mutations on Leukemogenesis and Targeting of Children With Acute Lymphoblastic Leukemia.

Frontiers In Cell And Developmental Biology
Qian, Jiabi J; Li, Zifeng Z; Pei, Kunlin K; Li, Ziping Z; Li, Chunjie C; Yan, Muxia M; Qian, Maoxiang M; Song, Yuanbin Y; Zhang, Hui H; He, Yingyi Y
Publication Date: 2022

Variant appearance in text: NRAS: G12A
PubMed Link: 35211470
Variant Present in the following documents:
  • Main text
  • DataSheet2.xlsx, sheet 8
View BVdb publication page



Integrated Genomic Analysis Identifies UBTF Tandem Duplications as a Recurrent Lesion in Pediatric Acute Myeloid Leukemia.

Blood Cancer Discovery
Umeda, Masayuki M; Ma, Jing J; Huang, Benjamin J BJ; Hagiwara, Kohei K; Westover, Tamara T; Abdelhamed, Sherif S; Barajas, Juan M JM; Thomas, Melvin E ME; Walsh, Michael P MP; Song, Guangchun G; Tian, Liqing L; Liu, Yanling Y; Chen, Xiaolong X; Kolekar, Pandurang P; Tran, Quang Q; Foy, Scott G SG; Maciaszek, Jamie L JL; Kleist, Andrew B AB; Leonti, Amanda R AR; Ju, Bengsheng B; Easton, John J; Wu, Huiyun H; Valentine, Virginia V; Valentine, Marcus B MB; Liu, Yen-Chun YC; Ries, Rhonda E RE; Smith, Jenny L JL; Parganas, Evan E; Iacobucci, Ilaria I; Hiltenbrand, Ryan R; Miller, Jonathan J; Myers, Jason R JR; Rampersaud, Evadnie E; Rahbarinia, Delaram D; Rusch, Michael M; Wu, Gang G; Inaba, Hiroto H; Wang, Yi-Cheng YC; Alonzo, Todd A TA; Downing, James R JR; Mullighan, Charles G CG; Pounds, Stanley S; Babu, M Madan MM; Zhang, Jinghui J; Rubnitz, Jeffrey E JE; Meshinchi, Soheil S; Ma, Xiaotu X; Klco, Jeffery M JM
Publication Date: 2022-05-05

Variant appearance in text: NRAS: G12A
PubMed Link: 35176137
Variant Present in the following documents:
  • bcd-21-0160_supplemental_tables_supp1-32.xlsx, sheet 18
View BVdb publication page



Chronic neutrophilic leukemia complicated with monoclonal gammopathy of undetermined significance: A case report and literature review.

Journal Of Clinical Laboratory Analysis
Gao, Jia-Pei JP; Zhai, Li-Jia LJ; Gao, Xiao-Hui XH; Min, Feng-Ling FL
Publication Date: 2022-04

Variant appearance in text: NRAS: G12A
PubMed Link: 35170077
Variant Present in the following documents:
  • Main text
  • JCLA-36-e24287.pdf
View BVdb publication page



Mutational profiling of melanomas in patients from the southeast coast of China.

Translational Cancer Research
Zheng, Ai-Wen AW; Jia, Dong-Dong DD; Zhou, Cheng-Cheng CC; Li, Tao T
Publication Date: 2020-08

Variant appearance in text: NRAS: G12A
PubMed Link: 35117841
Variant Present in the following documents:
  • Main text
View BVdb publication page



Prognostic Impact of Tumor Budding on Moroccan Colon Cancer Patients.

International Journal Of Surgical Oncology
El Agy, Fatima F; El Bardai, Sanae S; Bouguenouch, Laila L; Lahmidani, Nada N; El Abkari, Mohammed M; Benjelloun, El Bachir EB; Ousadden, Abdelmalek A; Mazaz, Khalid K; ImaneToughrai, ; Ibrahimi, Sidi Adil SA; Benbrahim, Zineb Z; Chbani, Laila L
Publication Date: 2022

Variant appearance in text: NRAS: G12A
PubMed Link: 35096426
Variant Present in the following documents:
  • IJSO2022-9334570.pdf
View BVdb publication page



KLF3 and PAX6 are candidate driver genes in late-stage, MSI-hypermutated endometrioid endometrial carcinomas.

Plos One
Rudd, Meghan L ML; Hansen, Nancy F NF; Zhang, Xiaolu X; Urick, Mary Ellen ME; Zhang, Suiyuan S; Merino, Maria J MJ; , ; Mullikin, James C JC; Brody, Lawrence C LC; Bell, Daphne W DW
Publication Date: 2022

Variant appearance in text: rs121913237
PubMed Link: 35081118
Variant Present in the following documents:
  • pone.0251286.s005.xlsx, sheet 8
View BVdb publication page



KLF3 and PAX6 are candidate driver genes in late-stage, MSI-hypermutated endometrioid endometrial carcinomas.

Plos One
Rudd, Meghan L ML; Hansen, Nancy F NF; Zhang, Xiaolu X; Urick, Mary Ellen ME; Zhang, Suiyuan S; Merino, Maria J MJ; , ; Mullikin, James C JC; Brody, Lawrence C LC; Bell, Daphne W DW
Publication Date: 2022

Variant appearance in text: rs121913237
PubMed Link: 35081118
Variant Present in the following documents:
  • pone.0251286.s005.xlsx, sheet 8
View BVdb publication page



Fusobacterium nucleatum and Bacteroides fragilis detection in colorectal tumours: Optimal target site and correlation with total bacterial load.

Plos One
Rye, Marie S MS; Garrett, Kerryn L KL; Holt, Robert A RA; Platell, Cameron F CF; McCoy, Melanie J MJ
Publication Date: 2022

Variant appearance in text: NRAS: G12A
PubMed Link: 34995318
Variant Present in the following documents:
  • Main text
  • pone.0262416.pdf
View BVdb publication page



Fusobacterium nucleatum and Bacteroides fragilis detection in colorectal tumours: Optimal target site and correlation with total bacterial load.

Plos One
Rye, Marie S MS; Garrett, Kerryn L KL; Holt, Robert A RA; Platell, Cameron F CF; McCoy, Melanie J MJ
Publication Date: 2022

Variant appearance in text: NRAS: G12A
PubMed Link: 34995318
Variant Present in the following documents:
  • Main text
  • pone.0262416.pdf
View BVdb publication page



Immunosuppression and outcomes in adult patients with de novo acute myeloid leukemia with normal karyotypes.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Ferraro, Francesca F; Miller, Christopher A CA; Christensen, Keegan A KA; Helton, Nichole M NM; O'Laughlin, Margaret M; Fronick, Catrina C CC; Fulton, Robert S RS; Kohlschmidt, Jessica J; Eisfeld, Ann-Kathrin AK; Bloomfield, Clara D CD; Ramakrishnan, Sai Mukund SM; Day, Ryan B RB; Wartman, Lukas D LD; Uy, Geoffrey L GL; Welch, John S JS; Christopher, Matthew J MJ; Heath, Sharon E SE; Baty, Jack D JD; Schuelke, Matthew J MJ; Payton, Jacqueline E JE; Spencer, David H DH; Rettig, Michael P MP; Link, Daniel C DC; Walter, Matthew J MJ; Westervelt, Peter P; DiPersio, John F JF; Ley, Timothy J TJ
Publication Date: 2021-12-07

Variant appearance in text: NRAS: G12A
PubMed Link: 34845035
Variant Present in the following documents:
  • pnas.2116427118.sd02.xlsx, sheet 1
View BVdb publication page



Immunosuppression and outcomes in adult patients with de novo acute myeloid leukemia with normal karyotypes.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Ferraro, Francesca F; Miller, Christopher A CA; Christensen, Keegan A KA; Helton, Nichole M NM; O'Laughlin, Margaret M; Fronick, Catrina C CC; Fulton, Robert S RS; Kohlschmidt, Jessica J; Eisfeld, Ann-Kathrin AK; Bloomfield, Clara D CD; Ramakrishnan, Sai Mukund SM; Day, Ryan B RB; Wartman, Lukas D LD; Uy, Geoffrey L GL; Welch, John S JS; Christopher, Matthew J MJ; Heath, Sharon E SE; Baty, Jack D JD; Schuelke, Matthew J MJ; Payton, Jacqueline E JE; Spencer, David H DH; Rettig, Michael P MP; Link, Daniel C DC; Walter, Matthew J MJ; Westervelt, Peter P; DiPersio, John F JF; Ley, Timothy J TJ
Publication Date: 2021-12-07

Variant appearance in text: NRAS: G12A
PubMed Link: 34845035
Variant Present in the following documents:
  • pnas.2116427118.sd02.xlsx, sheet 1
View BVdb publication page



The Pan-Tumor Landscape of Targetable Kinase Fusions in Circulating Tumor DNA.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Lee, Jessica K JK; Hazar-Rethinam, Mehlika M; Decker, Brennan B; Gjoerup, Ole O; Madison, Russell W RW; Lieber, Daniel S DS; Chung, Jon H JH; Schrock, Alexa B AB; Creeden, James J; Venstrom, Jeffrey J; Alexander, Brian B; Oxnard, Geoffrey R GR
Publication Date: 2022-02-15

Variant appearance in text: NRAS: G12A
PubMed Link: 34753780
Variant Present in the following documents:
  • 728.pdf
View BVdb publication page



Machine learning random forest for predicting oncosomatic variant NGS analysis.

Scientific Reports
Pellegrino, Eric E; Jacques, Coralie C; Beaufils, Nathalie N; Nanni, Isabelle I; Carlioz, Antoine A; Metellus, Philippe P; Ouafik, L'Houcine L
Publication Date: 2021-11-08

Variant appearance in text: NRAS: 35G>C
PubMed Link: 34750410
Variant Present in the following documents:
  • 41598_2021_1253_MOESM1_ESM.pdf
View BVdb publication page



Low neoantigen expression and poor T-cell priming underlie early immune escape in colorectal cancer.

Nature Cancer
Westcott, Peter M K PMK; Sacks, Nathan J NJ; Schenkel, Jason M JM; Ely, Zackery A ZA; Smith, Olivia O; Hauck, Haley H; Jaeger, Alex M AM; Zhang, Daniel D; Backlund, Coralie M CM; Beytagh, Mary C MC; Patten, J J JJ; Elbashir, Ryan R; Eng, George G; Irvine, Darrell J DJ; Yilmaz, Omer H OH; Jacks, Tyler T
Publication Date: 2021-10

Variant appearance in text: NRAS: 35G>C; Gly12Ala
PubMed Link: 34738089
Variant Present in the following documents:
  • NIHMS1725490-supplement-Source_Data_Figure_1.xlsx, sheet 1
View BVdb publication page



Genomic Abnormalities as Biomarkers and Therapeutic Targets in Acute Myeloid Leukemia.

Cancers
Ribeiro, Sara S; Eiring, Anna M AM; Khorashad, Jamshid S JS
Publication Date: 2021-10-09

Variant appearance in text: NRAS: G12A
PubMed Link: 34680203
Variant Present in the following documents:
  • Main text
View BVdb publication page



The retrospective molecular analysis of large or giant congenital melanocytic nevi in a group of Polish children.

Journal Of Mother And Child
Wertheim-Tysarowska, Katarzyna K; Szczygielski, Orest O; Seliga, Katarzyna K; Tysarowski, Andrzej A; Bal, Jerzy J; Michalak, Elżbieta E; Rygiel, Agnieszka Magdalena AM; Sawicka, Ewa E
Publication Date: 2021-10-11

Variant appearance in text: NRAS: 35G>C; Gly12Ala
PubMed Link: 34643354
Variant Present in the following documents:
  • Main text
  • jmotherandchild-25-019.pdf
View BVdb publication page