Modified eQTL and Somatic DNA Segment Alterations in Esophageal Squamous Cell Carcinoma for Genes Related to Immunity, DNA Repair, and Inflammation.
Cancers
Yang, Howard H HH; Liu, Huaitian H; Hu, Nan N; Su, Hua H; Wang, Chaoyu C; Giffen, Carol C; Goldstein, Alisa M AM; Taylor, Philip R PR; Lee, Maxwell P MP
Genetic Determinants Highlight the Existence of Shared Etiopathogenetic Mechanisms Characterizing Age-Related Macular Degeneration and Neurodegenerative Disorders.
Frontiers In Neurology
Strafella, Claudia C; Caputo, Valerio V; Termine, Andrea A; Fabrizio, Carlo C; Ruffo, Paola P; Potenza, Saverio S; Cusumano, Andrea A; Ricci, Federico F; Caltagirone, Carlo C; Giardina, Emiliano E; Cascella, Raffaella R
Two genetic variants explain the association of European ancestry with multiple sclerosis risk in African-Americans.
Scientific Reports
Nakatsuka, Nathan N; Patterson, Nick N; Patsopoulos, Nikolaos A NA; Altemose, Nicolas N; Tandon, Arti A; Beecham, Ashley H AH; McCauley, Jacob L JL; Isobe, Noriko N; Hauser, Stephen S; De Jager, Philip L PL; Hafler, David A DA; Oksenberg, Jorge R JR; Reich, David D
A genetic variant associated with multiple sclerosis inversely affects the expression of CD58 and microRNA-548ac from the same gene.
Plos Genetics
Hecker, Michael M; Boxberger, Nina N; Illner, Nicole N; Fitzner, Brit B; Schröder, Ina I; Winkelmann, Alexander A; Dudesek, Ales A; Meister, Stefanie S; Koczan, Dirk D; Lorenz, Peter P; Thiesen, Hans-Jürgen HJ; Zettl, Uwe Klaus UK
Payer, Lindsay M LM; Steranka, Jared P JP; Ardeljan, Daniel D; Walker, JaNiece J; Fitzgerald, Kathryn C KC; Calabresi, Peter A PA; Cooper, Thomas A TA; Burns, Kathleen H KH
Structural variants caused by Alu insertions are associated with risks for many human diseases.
Proceedings Of The National Academy Of Sciences Of The United States Of America
Payer, Lindsay M LM; Steranka, Jared P JP; Yang, Wan Rou WR; Kryatova, Maria M; Medabalimi, Sibyl S; Ardeljan, Daniel D; Liu, Chunhong C; Boeke, Jef D JD; Avramopoulos, Dimitri D; Burns, Kathleen H KH
Multiple sclerosis risk loci and disease severity in 7,125 individuals from 10 studies.
Neurology. Genetics
George, Michaela F MF; Briggs, Farren B S FB; Shao, Xiaorong X; Gianfrancesco, Milena A MA; Kockum, Ingrid I; Harbo, Hanne F HF; Celius, Elisabeth G EG; Bos, Steffan D SD; Hedström, Anna A; Shen, Ling L; Bernstein, Allan A; Alfredsson, Lars L; Hillert, Jan J; Olsson, Tomas T; Patsopoulos, Nikolaos A NA; De Jager, Philip L PL; Oturai, Annette B AB; Søndergaard, Helle B HB; Sellebjerg, Finn F; Sorensen, Per S PS; Gomez, Refujia R; Caillier, Stacy J SJ; Cree, Bruce A C BA; Oksenberg, Jorge R JR; Hauser, Stephen L SL; D'Alfonso, Sandra S; Leone, Maurizio A MA; Martinelli Boneschi, Filippo F; Sorosina, Melissa M; van der Mei, Ingrid I; Taylor, Bruce V BV; Zhou, Yuan Y; Schaefer, Catherine C; Barcellos, Lisa F LF
No evidence for shared genetic basis of common variants in multiple sclerosis and amyotrophic lateral sclerosis.
Human Molecular Genetics
Goris, An A; van Setten, Jessica J; Diekstra, Frank F; Ripke, Stephan S; Patsopoulos, Nikolaos A NA; Sawcer, Stephen J SJ; , ; van Es, Michael M; , ; Andersen, Peter M PM; Melki, Judith J; Meininger, Vincent V; Hardiman, Orla O; Landers, John E JE; Brown, Robert H RH; Shatunov, Aleksey A; Leigh, Nigel N; Al-Chalabi, Ammar A; Shaw, Christopher E CE; Traynor, Bryan J BJ; Chiò, Adriano A; Restagno, Gabriella G; Mora, Gabriele G; Ophoff, Roel A RA; Oksenberg, Jorge R JR; Van Damme, Philip P; Compston, Alastair A; Robberecht, Wim W; Dubois, Bénédicte B; van den Berg, Leonard H LH; De Jager, Philip L PL; Veldink, Jan H JH; de Bakker, Paul I W PI
Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis.
Nature Genetics
, ; Beecham, Ashley H AH; Patsopoulos, Nikolaos A NA; Xifara, Dionysia K DK; Davis, Mary F MF; Kemppinen, Anu A; Cotsapas, Chris C; Shah, Tejas S TS; Spencer, Chris C; Booth, David D; Goris, An A; Oturai, Annette A; Saarela, Janna J; Fontaine, Bertrand B; Hemmer, Bernhard B; Martin, Claes C; Zipp, Frauke F; D'Alfonso, Sandra S; Martinelli-Boneschi, Filippo F; Taylor, Bruce B; Harbo, Hanne F HF; Kockum, Ingrid I; Hillert, Jan J; Olsson, Tomas T; Ban, Maria M; Oksenberg, Jorge R JR; Hintzen, Rogier R; Barcellos, Lisa F LF; , ; , ; Agliardi, Cristina C; Alfredsson, Lars L; Alizadeh, Mehdi M; Anderson, Carl C; Andrews, Robert R; Søndergaard, Helle Bach HB; Baker, Amie A; Band, Gavin G; Baranzini, Sergio E SE; Barizzone, Nadia N; Barrett, Jeffrey J; Bellenguez, Céline C; Bergamaschi, Laura L; Bernardinelli, Luisa L; Berthele, Achim A; Biberacher, Viola V; Binder, Thomas M C TM; Blackburn, Hannah H; Bomfim, Izaura L IL; Brambilla, Paola P; Broadley, Simon S; Brochet, Bruno B; Brundin, Lou L; Buck, Dorothea D; Butzkueven, Helmut H; Caillier, Stacy J SJ; Camu, William W; Carpentier, Wassila W; Cavalla, Paola P; Celius, Elisabeth G EG; Coman, Irène I; Comi, Giancarlo G; Corrado, Lucia L; Cosemans, Leentje L; Cournu-Rebeix, Isabelle I; Cree, Bruce A C BA; Cusi, Daniele D; Damotte, Vincent V; Defer, Gilles G; Delgado, Silvia R SR; Deloukas, Panos P; di Sapio, Alessia A; Dilthey, Alexander T AT; Donnelly, Peter P; Dubois, Bénédicte B; Duddy, Martin M; Edkins, Sarah S; Elovaara, Irina I; Esposito, Federica F; Evangelou, Nikos N; Fiddes, Barnaby B; Field, Judith J; Franke, Andre A; Freeman, Colin C; Frohlich, Irene Y IY; Galimberti, Daniela D; Gieger, Christian C; Gourraud, Pierre-Antoine PA; Graetz, Christiane C; Graham, Andrew A; Grummel, Verena V; Guaschino, Clara C; Hadjixenofontos, Athena A; Hakonarson, Hakon H; Halfpenny, Christopher C; Hall, Gillian G; Hall, Per P; Hamsten, Anders A; Harley, James J; Harrower, Timothy T; Hawkins, Clive C; Hellenthal, Garrett G; Hillier, Charles C; Hobart, Jeremy J; Hoshi, Muni M; Hunt, Sarah E SE; Jagodic, Maja M; Jelčić, Ilijas I; Jochim, Angela A; Kendall, Brian B; Kermode, Allan A; Kilpatrick, Trevor T; Koivisto, Keijo K; Konidari, Ioanna I; Korn, Thomas T; Kronsbein, Helena H; Langford, Cordelia C; Larsson, Malin M; Lathrop, Mark M; Lebrun-Frenay, Christine C; Lechner-Scott, Jeannette J; Lee, Michelle H MH; Leone, Maurizio A MA; Leppä, Virpi V; Liberatore, Giuseppe G; Lie, Benedicte A BA; Lill, Christina M CM; Lindén, Magdalena M; Link, Jenny J; Luessi, Felix F; Lycke, Jan J; Macciardi, Fabio F; Männistö, Satu S; Manrique, Clara P CP; Martin, Roland R; Martinelli, Vittorio V; Mason, Deborah D; Mazibrada, Gordon G; McCabe, Cristin C; Mero, Inger-Lise IL; Mescheriakova, Julia J; Moutsianas, Loukas L; Myhr, Kjell-Morten KM; Nagels, Guy G; Nicholas, Richard R; Nilsson, Petra P; Piehl, Fredrik F; Pirinen, Matti M; Price, Siân E SE; Quach, Hong H; Reunanen, Mauri M; Robberecht, Wim W; Robertson, Neil P NP; Rodegher, Mariaemma M; Rog, David D; Salvetti, Marco M; Schnetz-Boutaud, Nathalie C NC; Sellebjerg, Finn F; Selter, Rebecca C RC; Schaefer, Catherine C; Shaunak, Sandip S; Shen, Ling L; Shields, Simon S; Siffrin, Volker V; Slee, Mark M; Sorensen, Per Soelberg PS; Sorosina, Melissa M; Sospedra, Mireia M; Spurkland, Anne A; Strange, Amy A; Sundqvist, Emilie E; Thijs, Vincent V; Thorpe, John J; Ticca, Anna A; Tienari, Pentti P; van Duijn, Cornelia C; Visser, Elizabeth M EM; Vucic, Steve S; Westerlind, Helga H; Wiley, James S JS; Wilkins, Alastair A; Wilson, James F JF; Winkelmann, Juliane J; Zajicek, John J; Zindler, Eva E; Haines, Jonathan L JL; Pericak-Vance, Margaret A MA; Ivinson, Adrian J AJ; Stewart, Graeme G; Hafler, David D; Hauser, Stephen L SL; Compston, Alastair A; McVean, Gil G; De Jager, Philip P; Sawcer, Stephen J SJ; McCauley, Jacob L JL
Genetic risk variants in African Americans with multiple sclerosis.
Neurology
Isobe, Noriko N; Gourraud, Pierre-Antoine PA; Harbo, Hanne F HF; Caillier, Stacy J SJ; Santaniello, Adam A; Khankhanian, Pouya P; Maiers, Martin M; Spellman, Stephen S; Cereb, Nezih N; Yang, SooYoung S; Pando, Marcelo J MJ; Piccio, Laura L; Cross, Anne H AH; De Jager, Philip L PL; Cree, Bruce A C BA; Hauser, Stephen L SL; Oksenberg, Jorge R JR
A genome-wide integrative genomic study localizes genetic factors influencing antibodies against Epstein-Barr virus nuclear antigen 1 (EBNA-1).
Plos Genetics
Rubicz, Rohina R; Yolken, Robert R; Drigalenko, Eugene E; Carless, Melanie A MA; Dyer, Thomas D TD; Bauman, Lara L; Melton, Phillip E PE; Kent, Jack W JW; Harley, John B JB; Curran, Joanne E JE; Johnson, Matthew P MP; Cole, Shelley A SA; Almasy, Laura L; Moses, Eric K EK; Dhurandhar, Nikhil V NV; Kraig, Ellen E; Blangero, John J; Leach, Charles T CT; Göring, Harald H H HH
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
Nature
, ; , ; Sawcer, Stephen S; Hellenthal, Garrett G; Pirinen, Matti M; Spencer, Chris C A CC; Patsopoulos, Nikolaos A NA; Moutsianas, Loukas L; Dilthey, Alexander A; Su, Zhan Z; Freeman, Colin C; Hunt, Sarah E SE; Edkins, Sarah S; Gray, Emma E; Booth, David R DR; Potter, Simon C SC; Goris, An A; Band, Gavin G; Oturai, Annette Bang AB; Strange, Amy A; Saarela, Janna J; Bellenguez, Céline C; Fontaine, Bertrand B; Gillman, Matthew M; Hemmer, Bernhard B; Gwilliam, Rhian R; Zipp, Frauke F; Jayakumar, Alagurevathi A; Martin, Roland R; Leslie, Stephen S; Hawkins, Stanley S; Giannoulatou, Eleni E; D'alfonso, Sandra S; Blackburn, Hannah H; Martinelli Boneschi, Filippo F; Liddle, Jennifer J; Harbo, Hanne F HF; Perez, Marc L ML; Spurkland, Anne A; Waller, Matthew J MJ; Mycko, Marcin P MP; Ricketts, Michelle M; Comabella, Manuel M; Hammond, Naomi N; Kockum, Ingrid I; McCann, Owen T OT; Ban, Maria M; Whittaker, Pamela P; Kemppinen, Anu A; Weston, Paul P; Hawkins, Clive C; Widaa, Sara S; Zajicek, John J; Dronov, Serge S; Robertson, Neil N; Bumpstead, Suzannah J SJ; Barcellos, Lisa F LF; Ravindrarajah, Rathi R; Abraham, Roby R; Alfredsson, Lars L; Ardlie, Kristin K; Aubin, Cristin C; Baker, Amie A; Baker, Katharine K; Baranzini, Sergio E SE; Bergamaschi, Laura L; Bergamaschi, Roberto R; Bernstein, Allan A; Berthele, Achim A; Boggild, Mike M; Bradfield, Jonathan P JP; Brassat, David D; Broadley, Simon A SA; Buck, Dorothea D; Butzkueven, Helmut H; Capra, Ruggero R; Carroll, William M WM; Cavalla, Paola P; Celius, Elisabeth G EG; Cepok, Sabine S; Chiavacci, Rosetta R; Clerget-Darpoux, Françoise F; Clysters, Katleen K; Comi, Giancarlo G; Cossburn, Mark M; Cournu-Rebeix, Isabelle I; Cox, Mathew B MB; Cozen, Wendy W; Cree, Bruce A C BA; Cross, Anne H AH; Cusi, Daniele D; Daly, Mark J MJ; Davis, Emma E; de Bakker, Paul I W PI; Debouverie, Marc M; D'hooghe, Marie Beatrice MB; Dixon, Katherine K; Dobosi, Rita R; Dubois, Bénédicte B; Ellinghaus, David D; Elovaara, Irina I; Esposito, Federica F; Fontenille, Claire C; Foote, Simon S; Franke, Andre A; Galimberti, Daniela D; Ghezzi, Angelo A; Glessner, Joseph J; Gomez, Refujia R; Gout, Olivier O; Graham, Colin C; Grant, Struan F A SF; Guerini, Franca Rosa FR; Hakonarson, Hakon H; Hall, Per P; Hamsten, Anders A; Hartung, Hans-Peter HP; Heard, Rob N RN; Heath, Simon S; Hobart, Jeremy J; Hoshi, Muna M; Infante-Duarte, Carmen C; Ingram, Gillian G; Ingram, Wendy W; Islam, Talat T; Jagodic, Maja M; Kabesch, Michael M; Kermode, Allan G AG; Kilpatrick, Trevor J TJ; Kim, Cecilia C; Klopp, Norman N; Koivisto, Keijo K; Larsson, Malin M; Lathrop, Mark M; Lechner-Scott, Jeannette S JS; Leone, Maurizio A MA; Leppä, Virpi V; Liljedahl, Ulrika U; Bomfim, Izaura Lima IL; Lincoln, Robin R RR; Link, Jenny J; Liu, Jianjun J; Lorentzen, Aslaug R AR; Lupoli, Sara S; Macciardi, Fabio F; Mack, Thomas T; Marriott, Mark M; Martinelli, Vittorio V; Mason, Deborah D; McCauley, Jacob L JL; Mentch, Frank F; Mero, Inger-Lise IL; Mihalova, Tania T; Montalban, Xavier X; Mottershead, John J; Myhr, Kjell-Morten KM; Naldi, Paola P; Ollier, William W; Page, Alison A; Palotie, Aarno A; Pelletier, Jean J; Piccio, Laura L; Pickersgill, Trevor T; Piehl, Fredrik F; Pobywajlo, Susan S; Quach, Hong L HL; Ramsay, Patricia P PP; Reunanen, Mauri M; Reynolds, Richard R; Rioux, John D JD; Rodegher, Mariaemma M; Roesner, Sabine S; Rubio, Justin P JP; Rückert, Ina-Maria IM; Salvetti, Marco M; Salvi, Erika E; Santaniello, Adam A; Schaefer, Catherine A CA; Schreiber, Stefan S; Schulze, Christian C; Scott, Rodney J RJ; Sellebjerg, Finn F; Selmaj, Krzysztof W KW; Sexton, David D; Shen, Ling L; Simms-Acuna, Brigid B; Skidmore, Sheila S; Sleiman, Patrick M A PM; Smestad, Cathrine C; Sørensen, Per Soelberg PS; Søndergaard, Helle Bach HB; Stankovich, Jim J; Strange, Richard C RC; Sulonen, Anna-Maija AM; Sundqvist, Emilie E; Syvänen, Ann-Christine AC; Taddeo, Francesca F; Taylor, Bruce B; Blackwell, Jenefer M JM; Tienari, Pentti P; Bramon, Elvira E; Tourbah, Ayman A; Brown, Matthew A MA; Tronczynska, Ewa E; Casas, Juan P JP; Tubridy, Niall N; Corvin, Aiden A; Vickery, Jane J; Jankowski, Janusz J; Villoslada, Pablo P; Markus, Hugh S HS; Wang, Kai K; Mathew, Christopher G CG; Wason, James J; Palmer, Colin N A CN; Wichmann, H-Erich HE; Plomin, Robert R; Willoughby, Ernest E; Rautanen, Anna A; Winkelmann, Juliane J; Wittig, Michael M; Trembath, Richard C RC; Yaouanq, Jacqueline J; Viswanathan, Ananth C AC; Zhang, Haitao H; Wood, Nicholas W NW; Zuvich, Rebecca R; Deloukas, Panos P; Langford, Cordelia C; Duncanson, Audrey A; Oksenberg, Jorge R JR; Pericak-Vance, Margaret A MA; Haines, Jonathan L JL; Olsson, Tomas T; Hillert, Jan J; Ivinson, Adrian J AJ; De Jager, Philip L PL; Peltonen, Leena L; Stewart, Graeme J GJ; Hafler, David A DA; Hauser, Stephen L SL; McVean, Gil G; Donnelly, Peter P; Compston, Alastair A
Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.
Human Molecular Genetics
Baranzini, Sergio E SE; Wang, Joanne J; Gibson, Rachel A RA; Galwey, Nicholas N; Naegelin, Yvonne Y; Barkhof, Frederik F; Radue, Ernst-Wilhelm EW; Lindberg, Raija L P RL; Uitdehaag, Bernard M G BM; Johnson, Michael R MR; Angelakopoulou, Aspasia A; Hall, Leslie L; Richardson, Jill C JC; Prinjha, Rab K RK; Gass, Achim A; Geurts, Jeroen J G JJ; Kragt, Jolijn J; Sombekke, Madeleine M; Vrenken, Hugo H; Qualley, Pamela P; Lincoln, Robin R RR; Gomez, Refujia R; Caillier, Stacy J SJ; George, Michaela F MF; Mousavi, Hourieh H; Guerrero, Rosa R; Okuda, Darin T DT; Cree, Bruce A C BA; Green, Ari J AJ; Waubant, Emmanuelle E; Goodin, Douglas S DS; Pelletier, Daniel D; Matthews, Paul M PM; Hauser, Stephen L SL; Kappos, Ludwig L; Polman, Chris H CH; Oksenberg, Jorge R JR