Assessment of the Potential Role of Selected Single Nucleotide Polymorphisms (SNPs) of Genes Related to the Functioning of Regulatory T Cells in the Pathogenesis of Psoriasis.
International Journal Of Molecular Sciences
Purzycka-Bohdan, Dorota D; Nedoszytko, Bogusław B; Sobalska-Kwapis, Marta M; Zabłotna, Monika M; Żmijewski, Michał A MA; Wierzbicka, Justyna J; Gleń, Jolanta J; Strapagiel, Dominik D; Szczerkowska-Dobosz, Aneta A; Nowicki, Roman J RJ
Cellular and molecular features of COVID-19 associated ARDS: therapeutic relevance.
Journal Of Inflammation (London, England)
Scaramuzzo, Gaetano G; Nucera, Francesco F; Asmundo, Alessio A; Messina, Roberto R; Mari, Matilde M; Montanaro, Federica F; Johansen, Matt D MD; Monaco, Francesco F; Fadda, Guido G; Tuccari, Giovanni G; Hansbro, Nicole G NG; Hansbro, Philip M PM; Hansel, Trevor T TT; Adcock, Ian M IM; David, Antonio A; Kirkham, Paul P; Caramori, Gaetano G; Volta, Carlo Alberto CA; Spadaro, Savino S
Clinical Value of IL6R Gene Variants as Predictive Biomarkers for Toxicity to Tocilizumab in Patients with Rheumatoid Arthritis.
Journal Of Personalized Medicine
Sainz, Luis L; Riera, Pau P; Moya, Patricia P; Bernal, Sara S; Casademont, Jordi J; Díaz-Torné, Cesar C; Millán, Ana Milena AM; Park, Hye Sang HS; Lasa, Adriana A; Corominas, Héctor H
Mendelian randomisation and experimental medicine approaches to interleukin-6 as a drug target in pulmonary arterial hypertension.
The European Respiratory Journal
Toshner, Mark M; Church, Colin C; Harbaum, Lars L; Rhodes, Christopher C; Villar Moreschi, Sofia S SS; Liley, James J; Jones, Rowena R; Arora, Amit A; Batai, Ken K; Desai, Ankit A AA; Coghlan, John G JG; Gibbs, J Simon R JSR; Gor, Dee D; Gräf, Stefan S; Harlow, Louise L; Hernandez-Sanchez, Jules J; Howard, Luke S LS; Humbert, Marc M; Karnes, Jason J; Kiely, David G DG; Kittles, Rick R; Knightbridge, Emily E; Lam, Brian B; Lutz, Katie A KA; Nichols, William C WC; Pauciulo, Michael W MW; Pepke-Zaba, Joanna J; Suntharalingam, Jay J; Soubrier, Florent F; Trembath, Richard C RC; Schwantes-An, Tae-Hwi L TL; Wort, S John SJ; Wilkins, Martin R MR; Gaine, Sean S; Morrell, Nicholas W NW; Corris, Paul A PA; ,
Characterization of Rheumatoid Arthritis Risk-Associated SNPs and Identification of Novel Therapeutic Sites Using an In-Silico Approach.
Biology
Akhtar, Mehran M; Ali, Yasir Y; Islam, Zia-Ul ZU; Arshad, Maria M; Rauf, Mamoona M; Ali, Muhammad M; Maodaa, Saleh N SN; Al-Farraj, Saleh A SA; El-Serehy, Hamed A HA; Jalil, Fazal F
Activated IL-6 signaling contributes to the pathogenesis of, and is a novel therapeutic target for, CALR-mutated MPNs.
Blood Advances
Balliu, Manjola M; Calabresi, Laura L; Bartalucci, Niccolò N; Romagnoli, Simone S; Maggi, Laura L; Manfredini, Rossella R; Lulli, Matteo M; Guglielmelli, Paola P; Vannucchi, Alessandro Maria AM
Genome-wide association study of circulating interleukin 6 levels identifies novel loci.
Human Molecular Genetics
Ahluwalia, Tarunveer S TS; Prins, Bram P BP; Abdollahi, Mohammadreza M; Armstrong, Nicola J NJ; Aslibekyan, Stella S; Bain, Lisa L; Jefferis, Barbara B; Baumert, Jens J; Beekman, Marian M; Ben-Shlomo, Yoav Y; Bis, Joshua C JC; Mitchell, Braxton D BD; de Geus, Eco E; Delgado, Graciela E GE; Marek, Diana D; Eriksson, Joel J; Kajantie, Eero E; Kanoni, Stavroula S; Kemp, John P JP; Lu, Chen C; Marioni, Riccardo E RE; McLachlan, Stela S; Milaneschi, Yuri Y; Nolte, Ilja M IM; Petrelis, Alexandros M AM; Porcu, Eleonora E; Sabater-Lleal, Maria M; Naderi, Elnaz E; Seppälä, Ilkka I; Shah, Tina T; Singhal, Gaurav G; Standl, Marie M; Teumer, Alexander A; Thalamuthu, Anbupalam A; Thiering, Elisabeth E; Trompet, Stella S; Ballantyne, Christie M CM; Benjamin, Emelia J EJ; Casas, Juan P JP; Toben, Catherine C; Dedoussis, George G; Deelen, Joris J; Durda, Peter P; Engmann, Jorgen J; Feitosa, Mary F MF; Grallert, Harald H; Hammarstedt, Ann A; Harris, Sarah E SE; Homuth, Georg G; Hottenga, Jouke-Jan JJ; Jalkanen, Sirpa S; Jamshidi, Yalda Y; Jawahar, Magdalene C MC; Jess, Tine T; Kivimaki, Mika M; Kleber, Marcus E ME; Lahti, Jari J; Liu, Yongmei Y; Marques-Vidal, Pedro P; Mellström, Dan D; Mooijaart, Simon P SP; Müller-Nurasyid, Martina M; Penninx, Brenda B; Revez, Joana A JA; Rossing, Peter P; Räikkönen, Katri K; Sattar, Naveed N; Scharnagl, Hubert H; Sennblad, Bengt B; Silveira, Angela A; Pourcain, Beate St BS; Timpson, Nicholas J NJ; Trollor, Julian J; , ; van Dongen, Jenny J; Van Heemst, Diana D; Visvikis-Siest, Sophie S; Vollenweider, Peter P; Völker, Uwe U; Waldenberger, Melanie M; Willemsen, Gonneke G; Zabaneh, Delilah D; Morris, Richard W RW; Arnett, Donna K DK; Baune, Bernhard T BT; Boomsma, Dorret I DI; Chang, Yen-Pei C YC; Deary, Ian J IJ; Deloukas, Panos P; Eriksson, Johan G JG; Evans, David M DM; Ferreira, Manuel A MA; Gaunt, Tom T; Gudnason, Vilmundur V; Hamsten, Anders A; Heinrich, Joachim J; Hingorani, Aroon A; Humphries, Steve E SE; Jukema, J Wouter JW; Koenig, Wolfgang W; Kumari, Meena M; Kutalik, Zoltan Z; Lawlor, Deborah A DA; Lehtimäki, Terho T; März, Winfried W; Mather, Karen A KA; Naitza, Silvia S; Nauck, Matthias M; Ohlsson, Claes C; Price, Jackie F JF; Raitakari, Olli O; Rice, Ken K; Sachdev, Perminder S PS; Slagboom, Eline E; Sørensen, Thorkild I A TIA; Spector, Tim T; Stacey, David D; Stathopoulou, Maria G MG; Tanaka, Toshiko T; Wannamethee, S Goya SG; Whincup, Peter P; Rotter, Jerome I JI; Dehghan, Abbas A; Boerwinkle, Eric E; Psaty, Bruce M BM; Snieder, Harold H; Alizadeh, Behrooz Z BZ
Genome-wide association study of high-sensitivity C-reactive protein, D-dimer, and interleukin-6 levels in multiethnic HIV+ cohorts.
Aids (London, England)
Sherman, Brad T BT; Hu, Xiaojun X; Singh, Kanal K; Haine, Lillian L; Rupert, Adam W AW; Neaton, James D JD; Lundgren, Jens D JD; Imamichi, Tomozumi T; Chang, Weizhong W; Lane, H Clifford HC; ,
Sex-Specific Genetic Susceptibility to Adverse Neurodevelopmental Outcome in Offspring of Pregnancies at Risk of Early Preterm Delivery.
American Journal Of Perinatology
Varner, Michael W MW; Costantine, Maged M MM; Jablonski, Kathleen A KA; Rouse, Dwight J DJ; Mercer, Brian M BM; Leveno, Kenneth J KJ; Reddy, Uma M UM; Buhimschi, Catalin C; Wapner, Ronald J RJ; Sorokin, Yoram Y; Thorp, John M JM; Ramin, Susan M SM; Malone, Fergal D FD; Carpenter, Marshall M; O'sullivan, Mary J MJ; Peaceman, Alan M AM; Dudley, Donald J DJ; Caritis, Steve N SN; ,
Genetic Variation, Magnesium Sulfate Exposure, and Adverse Neurodevelopmental Outcomes Following Preterm Birth.
American Journal Of Perinatology
Clark, Erin A S EAS; Weiner, Steven J SJ; Rouse, Dwight J DJ; Mercer, Brian M BM; Reddy, Uma M UM; Iams, Jay D JD; Wapner, Ronald J RJ; Sorokin, Yoram Y; Malone, Fergal D FD; O'Sullivan, Mary J MJ; Peaceman, Alan M AM; Hankins, Gary D V GDV; Dudley, Donald J DJ; Caritis, Steve N SN; ,
Associations between SNPs and immune-related circulating proteins in schizophrenia.
Scientific Reports
Chan, Man K MK; Cooper, Jason D JD; Heilmann-Heimbach, Stefanie S; Frank, Josef J; Witt, Stephanie H SH; Nöthen, Markus M MM; Steiner, Johann J; Rietschel, Marcella M; Bahn, Sabine S
Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci.
Circulation Research
Jones, Gregory T GT; Tromp, Gerard G; Kuivaniemi, Helena H; Gretarsdottir, Solveig S; Baas, Annette F AF; Giusti, Betti B; Strauss, Ewa E; Van't Hof, Femke N G FN; Webb, Thomas R TR; Erdman, Robert R; Ritchie, Marylyn D MD; Elmore, James R JR; Verma, Anurag A; Pendergrass, Sarah S; Kullo, Iftikhar J IJ; Ye, Zi Z; Peissig, Peggy L PL; Gottesman, Omri O; Verma, Shefali S SS; Malinowski, Jennifer J; Rasmussen-Torvik, Laura J LJ; Borthwick, Kenneth M KM; Smelser, Diane T DT; Crosslin, David R DR; de Andrade, Mariza M; Ryer, Evan J EJ; McCarty, Catherine A CA; Böttinger, Erwin P EP; Pacheco, Jennifer A JA; Crawford, Dana C DC; Carrell, David S DS; Gerhard, Glenn S GS; Franklin, David P DP; Carey, David J DJ; Phillips, Victoria L VL; Williams, Michael J A MJ; Wei, Wenhua W; Blair, Ross R; Hill, Andrew A AA; Vasudevan, Thodor M TM; Lewis, David R DR; Thomson, Ian A IA; Krysa, Jo J; Hill, Geraldine B GB; Roake, Justin J; Merriman, Tony R TR; Oszkinis, Grzegorz G; Galora, Silvia S; Saracini, Claudia C; Abbate, Rosanna R; Pulli, Raffaele R; Pratesi, Carlo C; Saratzis, Athanasios A; Verissimo, Ana R AR; Bumpstead, Suzannah S; Badger, Stephen A SA; Clough, Rachel E RE; Cockerill, Gillian G; Hafez, Hany H; Scott, D Julian A DJ; Futers, T Simon TS; Romaine, Simon P R SP; Bridge, Katherine K; Griffin, Kathryn J KJ; Bailey, Marc A MA; Smith, Alberto A; Thompson, Matthew M MM; van Bockxmeer, Frank M FM; Matthiasson, Stefan E SE; Thorleifsson, Gudmar G; Thorsteinsdottir, Unnur U; Blankensteijn, Jan D JD; Teijink, Joep A W JA; Wijmenga, Cisca C; de Graaf, Jacqueline J; Kiemeney, Lambertus A LA; Lindholt, Jes S JS; Hughes, Anne A; Bradley, Declan T DT; Stirrups, Kathleen K; Golledge, Jonathan J; Norman, Paul E PE; Powell, Janet T JT; Humphries, Steve E SE; Hamby, Stephen E SE; Goodall, Alison H AH; Nelson, Christopher P CP; Sakalihasan, Natzi N; Courtois, Audrey A; Ferrell, Robert E RE; Eriksson, Per P; Folkersen, Lasse L; Franco-Cereceda, Anders A; Eicher, John D JD; Johnson, Andrew D AD; Betsholtz, Christer C; Ruusalepp, Arno A; Franzén, Oscar O; Schadt, Eric E EE; Björkegren, Johan L M JL; Lipovich, Leonard L; Drolet, Anne M AM; Verhoeven, Eric L EL; Zeebregts, Clark J CJ; Geelkerken, Robert H RH; van Sambeek, Marc R MR; van Sterkenburg, Steven M SM; de Vries, Jean-Paul JP; Stefansson, Kari K; Thompson, John R JR; de Bakker, Paul I W PI; Deloukas, Panos P; Sayers, Robert D RD; Harrison, Seamus C SC; van Rij, Andre M AM; Samani, Nilesh J NJ; Bown, Matthew J MJ
Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study.
Plos Medicine
Prins, Bram P BP; Abbasi, Ali A; Wong, Anson A; Vaez, Ahmad A; Nolte, Ilja I; Franceschini, Nora N; Stuart, Philip E PE; Guterriez Achury, Javier J; Mistry, Vanisha V; Bradfield, Jonathan P JP; Valdes, Ana M AM; Bras, Jose J; Shatunov, Aleksey A; , ; , ; , ; , ; , ; , ; , ; , ; , ; , ; , ; , ; , ; , ; Lu, Chen C; Han, Buhm B; Raychaudhuri, Soumya S; Bevan, Steve S; Mayes, Maureen D MD; Tsoi, Lam C LC; Evangelou, Evangelos E; Nair, Rajan P RP; Grant, Struan F A SF; Polychronakos, Constantin C; Radstake, Timothy R D TR; van Heel, David A DA; Dunstan, Melanie L ML; Wood, Nicholas W NW; Al-Chalabi, Ammar A; Dehghan, Abbas A; Hakonarson, Hakon H; Markus, Hugh S HS; Elder, James T JT; Knight, Jo J; Arking, Dan E DE; Spector, Timothy D TD; Koeleman, Bobby P C BP; van Duijn, Cornelia M CM; Martin, Javier J; Morris, Andrew P AP; Weersma, Rinse K RK; Wijmenga, Cisca C; Munroe, Patricia B PB; Perry, John R B JR; Pouget, Jennie G JG; Jamshidi, Yalda Y; Snieder, Harold H; Alizadeh, Behrooz Z BZ
Many obesity-associated SNPs strongly associate with DNA methylation changes at proximal promoters and enhancers.
Genome Medicine
Voisin, Sarah S; Almén, Markus Sällman MS; Zheleznyakova, Galina Y GY; Lundberg, Lina L; Zarei, Sanaz S; Castillo, Sandra S; Eriksson, Fia Ence FE; Nilsson, Emil K EK; Blüher, Matthias M; Böttcher, Yvonne Y; Kovacs, Peter P; Klovins, Janis J; Rask-Andersen, Mathias M; Schiöth, Helgi B HB
Analysis of the role of interleukin 6 receptor haplotypes in the regulation of circulating levels of inflammatory biomarkers and risk of coronary heart disease.
Plos One
Gigante, Bruna B; Strawbridge, Rona J RJ; Velasquez, Ilais Moreno IM; Golabkesh, Zahra Z; Silveira, Angela A; Goel, Anuj A; Baldassarre, Damiano D; Veglia, Fabrizio F; Tremoli, Elena E; Clarke, Robert R; Watkins, Hugh H; Hamsten, Anders A; Humphries, Steve E SE; de Faire, Ulf U
Genome-wide association study of CSF levels of 59 alzheimer's disease candidate proteins: significant associations with proteins involved in amyloid processing and inflammation.
Plos Genetics
Kauwe, John S K JS; Bailey, Matthew H MH; Ridge, Perry G PG; Perry, Rachel R; Wadsworth, Mark E ME; Hoyt, Kaitlyn L KL; Staley, Lyndsay A LA; Karch, Celeste M CM; Harari, Oscar O; Cruchaga, Carlos C; Ainscough, Benjamin J BJ; Bales, Kelly K; Pickering, Eve H EH; Bertelsen, Sarah S; , ; Fagan, Anne M AM; Holtzman, David M DM; Morris, John C JC; Goate, Alison M AM
Polymorphisms in the inflammatory pathway genes TLR2, TLR4, TLR9, LY96, NFKBIA, NFKB1, TNFA, TNFRSF1A, IL6R, IL10, IL23R, PTPN22, and PPARG are associated with susceptibility of inflammatory bowel disease in a Danish cohort.
Plos One
Bank, Steffen S; Skytt Andersen, Paal P; Burisch, Johan J; Pedersen, Natalia N; Roug, Stine S; Galsgaard, Julie J; Ydegaard Turino, Stine S; Brodersen, Jacob Broder JB; Rashid, Shaista S; Kaiser Rasmussen, Britt B; Avlund, Sara S; Bastholm Olesen, Thomas T; Jürgen Hoffmann, Hans H; Kragh Thomsen, Marianne M; Ostergaard Thomsen, Vibeke V; Frydenberg, Morten M; Andersen Nexø, Bjørn B; Sode, Jacob J; Vogel, Ulla U; Andersen, Vibeke V
The contribution of the functional IL6R polymorphism rs2228145, eQTLs and other genome-wide SNPs to the heritability of plasma sIL-6R levels.
Behavior Genetics
van Dongen, Jenny J; Jansen, Rick R; Smit, Dirk D; Hottenga, Jouke-Jan JJ; Mbarek, Hamdi H; Willemsen, Gonneke G; Kluft, Cornelis C; , ; Penninx, Brenda W J BW; Ferreira, Manuel A MA; Boomsma, Dorret I DI; de Geus, Eco J C EJ
Are C-reactive protein associated genetic variants associated with serum levels and retinal markers of microvascular pathology in Asian populations from Singapore?
Plos One
Dorajoo, Rajkumar R; Li, Ruoying R; Ikram, Mohammad Kamran MK; Liu, Jianjun J; Froguel, Philippe P; Lee, Jeannette J; Sim, Xueling X; Ong, Rick Twee-Hee RT; Tay, Wan Ting WT; Peng, Chen C; Young, Terri L TL; Blakemore, Alexandra I F AI; Cheng, Ching Yu CY; Aung, Tin T; Mitchell, Paul P; Wang, Jie Jin JJ; Klaver, Caroline C CC; Boerwinkle, Eric E; Klein, Ronald R; Siscovick, David S DS; Jensen, Richard A RA; Gudnason, Vilmundur V; Smith, Albert Vernon AV; Teo, Yik Ying YY; Wong, Tien Yin TY; Tai, E-Shyong ES; Heng, Chew-Kiat CK; Friedlander, Yechiel Y
Interleukin-6 receptor polymorphism is prevalent in HIV-negative Castleman Disease and is associated with increased soluble interleukin-6 receptor levels.
Plos One
Stone, Katie K; Woods, Emily E; Szmania, Susann M SM; Stephens, Owen W OW; Garg, Tarun K TK; Barlogie, Bart B; Shaughnessy, John D JD; Hall, Brett B; Reddy, Manjula M; Hoering, Antje A; Hansen, Emily E; van Rhee, Frits F
Single nucleotide polymorphisms (SNPs) involved in insulin resistance, weight regulation, lipid metabolism and inflammation in relation to metabolic syndrome: an epidemiological study.
Cardiovascular Diabetology
Povel, Cécile M CM; Boer, Jolanda M A JM; Onland-Moret, N Charlotte NC; Dollé, Martijn E T ME; Feskens, Edith J M EJ; van der Schouw, Yvonne T YT
C-reactive protein (CRP) promoter polymorphisms influence circulating CRP levels in a genome-wide association study of African Americans.
Human Molecular Genetics
Doumatey, Ayo P AP; Chen, Guanjie G; Tekola Ayele, Fasil F; Zhou, Jie J; Erdos, Michael M; Shriner, Daniel D; Huang, Hanxia H; Adeleye, Jokotade J; Balogun, Williams W; Fasanmade, Olufemi O; Johnson, Thomas T; Oli, Johnnie J; Okafor, Godfrey G; Amoah, Albert A; Eghan, Benjamin A BA; Agyenim-Boateng, Kofi K; Acheampong, Joseph J; Adebamowo, Clement C; Gerry, Norman P NP; Christman, Michael F MF; Adeyemo, Adebowale A; Rotimi, Charles N CN
The role of inflammatory pathway genetic variation on maternal metabolic phenotypes during pregnancy.
Plos One
Urbanek, Margrit M; Hayes, M Geoffrey MG; Lee, Hoon H; Freathy, Rachel M RM; Lowe, Lynn P LP; Ackerman, Christine C; Jafari, Nadereh N; Dyer, Alan R AR; Cox, Nancy J NJ; Dunger, David B DB; Hattersley, Andrew T AT; Metzger, Boyd E BE; Lowe, William L WL
The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis.
Lancet (London, England)
, ; Swerdlow, Daniel I DI; Holmes, Michael V MV; Kuchenbaecker, Karoline B KB; Engmann, Jorgen E L JE; Shah, Tina T; Sofat, Reecha R; Guo, Yiran Y; Chung, Christina C; Peasey, Anne A; Pfister, Roman R; Mooijaart, Simon P SP; Ireland, Helen A HA; Leusink, Maarten M; Langenberg, Claudia C; Li, Ka Wah KW; Palmen, Jutta J; Howard, Philip P; Cooper, Jackie A JA; Drenos, Fotios F; Hardy, John J; Nalls, Michael A MA; Li, Yun Rose YR; Lowe, Gordon G; Stewart, Marlene M; Bielinski, Suzette J SJ; Peto, Julian J; Timpson, Nicholas J NJ; Gallacher, John J; Dunlop, Malcolm M; Houlston, Richard R; Tomlinson, Ian I; Tzoulaki, Ioanna I; Luan, Jian'an J; Boer, Jolanda M A JM; Forouhi, Nita G NG; Onland-Moret, N Charlotte NC; van der Schouw, Yvonne T YT; Schnabel, Renate B RB; Hubacek, Jaroslav A JA; Kubinova, Ruzena R; Baceviciene, Migle M; Tamosiunas, Abdonas A; Pajak, Andrzej A; Topor-Madry, Roman R; Malyutina, Sofia S; Baldassarre, Damiano D; Sennblad, Bengt B; Tremoli, Elena E; de Faire, Ulf U; Ferrucci, Luigi L; Bandenelli, Stefania S; Tanaka, Toshiko T; Meschia, James F JF; Singleton, Andrew A; Navis, Gerjan G; Mateo Leach, Irene I; Bakker, Stephan J L SJ; Gansevoort, Ron T RT; Ford, Ian I; Epstein, Stephen E SE; Burnett, Mary Susan MS; Devaney, Joe M JM; Jukema, J Wouter JW; Westendorp, Rudi G J RG; Jan de Borst, Gert G; van der Graaf, Yolanda Y; de Jong, Pim A PA; Mailand-van der Zee, Anke-Hilse AH; Klungel, Olaf H OH; de Boer, Anthonius A; Doevendans, Pieter A PA; Stephens, Jeffrey W JW; Eaton, Charles B CB; Robinson, Jennifer G JG; Manson, JoAnn E JE; Fowkes, F Gerry FG; Frayling, Timonthy M TM; Price, Jackie F JF; Whincup, Peter H PH; Morris, Richard W RW; Lawlor, Debbie A DA; Smith, George Davey GD; Ben-Shlomo, Yoav Y; Redline, Susan S; Lange, Leslie A LA; Kumari, Meena M; Wareham, Nick J NJ; Verschuren, W M Monique WM; Benjamin, Emelia J EJ; Whittaker, John C JC; Hamsten, Anders A; Dudbridge, Frank F; Delaney, J A Chris JA; Wong, Andrew A; Kuh, Diana D; Hardy, Rebecca R; Castillo, Berta Almoguera BA; Connolly, John J JJ; van der Harst, Pim P; Brunner, Eric J EJ; Marmot, Michael G MG; Wassel, Christina L CL; Humphries, Steve E SE; Talmud, Philippa J PJ; Kivimaki, Mika M; Asselbergs, Folkert W FW; Voevoda, Mikhail M; Bobak, Martin M; Pikhart, Hynek H; Wilson, James G JG; Hakonarson, Hakon H; Reiner, Alex P AP; Keating, Brendan J BJ; Sattar, Naveed N; Hingorani, Aroon D AD; Casas, Juan Pablo JP
Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies.
Lancet (London, England)
, ; Sarwar, Nadeem N; Butterworth, Adam S AS; Freitag, Daniel F DF; Gregson, John J; Willeit, Peter P; Gorman, Donal N DN; Gao, Pei P; Saleheen, Danish D; Rendon, Augusto A; Nelson, Christopher P CP; Braund, Peter S PS; Hall, Alistair S AS; Chasman, Daniel I DI; Tybjærg-Hansen, Anne A; Chambers, John C JC; Benjamin, Emelia J EJ; Franks, Paul W PW; Clarke, Robert R; Wilde, Arthur A M AA; Trip, Mieke D MD; Steri, Maristella M; Witteman, Jacqueline C M JC; Qi, Lu L; van der Schoot, C Ellen CE; de Faire, Ulf U; Erdmann, Jeanette J; Stringham, Heather M HM; Koenig, Wolfgang W; Rader, Daniel J DJ; Melzer, David D; Reich, David D; Psaty, Bruce M BM; Kleber, Marcus E ME; Panagiotakos, Demosthenes B DB; Willeit, Johann J; Wennberg, Patrik P; Woodward, Mark M; Adamovic, Svetlana S; Rimm, Eric B EB; Meade, Tom W TW; Gillum, Richard F RF; Shaffer, Jonathan A JA; Hofman, Albert A; Onat, Altan A; Sundström, Johan J; Wassertheil-Smoller, Sylvia S; Mellström, Dan D; Gallacher, John J; Cushman, Mary M; Tracy, Russell P RP; Kauhanen, Jussi J; Karlsson, Magnus M; Salonen, Jukka T JT; Wilhelmsen, Lars L; Amouyel, Philippe P; Cantin, Bernard B; Best, Lyle G LG; Ben-Shlomo, Yoav Y; Manson, JoAnn E JE; Davey-Smith, George G; de Bakker, Paul I W PI; O'Donnell, Christopher J CJ; Wilson, James F JF; Wilson, Anthony G AG; Assimes, Themistocles L TL; Jansson, John-Olov JO; Ohlsson, Claes C; Tivesten, Åsa Å; Ljunggren, Östen Ö; Reilly, Muredach P MP; Hamsten, Anders A; Ingelsson, Erik E; Cambien, Francois F; Hung, Joseph J; Thomas, G Neil GN; Boehnke, Michael M; Schunkert, Heribert H; Asselbergs, Folkert W FW; Kastelein, John J P JJ; Gudnason, Vilmundur V; Salomaa, Veikko V; Harris, Tamara B TB; Kooner, Jaspal S JS; Allin, Kristine H KH; Nordestgaard, Børge G BG; Hopewell, Jemma C JC; Goodall, Alison H AH; Ridker, Paul M PM; Hólm, Hilma H; Watkins, Hugh H; Ouwehand, Willem H WH; Samani, Nilesh J NJ; Kaptoge, Stephen S; Di Angelantonio, Emanuele E; Harari, Olivier O; Danesh, John J
Large-scale candidate gene analysis in whites and African Americans identifies IL6R polymorphism in relation to atrial fibrillation: the National Heart, Lung, and Blood Institute's Candidate Gene Association Resource (CARe) project.
Circulation. Cardiovascular Genetics
Schnabel, Renate B RB; Kerr, Kathleen F KF; Lubitz, Steven A SA; Alkylbekova, Ermeg L EL; Marcus, Gregory M GM; Sinner, Moritz F MF; Magnani, Jared W JW; Wolf, Philip A PA; Deo, Rajat R; Lloyd-Jones, Donald M DM; Lunetta, Kathryn L KL; Mehra, Reena R; Levy, Daniel D; Fox, Ervin R ER; Arking, Dan E DE; Mosley, Thomas H TH; Müller-Nurasyid, Martina M; Young, Taylor R TR; Wichmann, H-Erich HE; Seshadri, Sudha S; Farlow, Deborah N DN; Rotter, Jerome I JI; Soliman, Elsayed Z EZ; Glazer, Nicole L NL; Wilson, James G JG; Breteler, Monique M B MM; Sotoodehnia, Nona N; Newton-Cheh, Christopher C; Kääb, Stefan S; Ellinor, Patrick T PT; Alonso, Alvaro A; Benjamin, Emelia J EJ; Heckbert, Susan R SR; ,
Association of genomic loci from a cardiovascular gene SNP array with fibrinogen levels in European Americans and African-Americans from six cohort studies: the Candidate Gene Association Resource (CARe).
Blood
Wassel, Christina L CL; Lange, Leslie A LA; Keating, Brendan J BJ; Taylor, Kira C KC; Johnson, Andrew D AD; Palmer, Cameron C; Ho, Lindsey A LA; Smith, Nicholas L NL; Lange, Ethan M EM; Li, Yun Y; Yang, Qiong Q; Delaney, Joseph A JA; Tang, Weihong W; Tofler, Geoffrey G; Redline, Susan S; Taylor, Herman A HA; Wilson, James G JG; Tracy, Russell P RP; Jacobs, David R DR; Folsom, Aaron R AR; Green, David D; O'Donnell, Christopher J CJ; Reiner, Alexander P AP
Novel loci, including those related to Crohn disease, psoriasis, and inflammation, identified in a genome-wide association study of fibrinogen in 17 686 women: the Women's Genome Health Study.
Circulation. Cardiovascular Genetics
Danik, Jacqueline S JS; Paré, Guillaume G; Chasman, Daniel I DI; Zee, Robert Y L RY; Kwiatkowski, David J DJ; Parker, Alex A; Miletich, Joseph P JP; Ridker, Paul M PM
Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease.
Jama
Elliott, Paul P; Chambers, John C JC; Zhang, Weihua W; Clarke, Robert R; Hopewell, Jemma C JC; Peden, John F JF; Erdmann, Jeanette J; Braund, Peter P; Engert, James C JC; Bennett, Derrick D; Coin, Lachlan L; Ashby, Deborah D; Tzoulaki, Ioanna I; Brown, Ian J IJ; Mt-Isa, Shahrul S; McCarthy, Mark I MI; Peltonen, Leena L; Freimer, Nelson B NB; Farrall, Martin M; Ruokonen, Aimo A; Hamsten, Anders A; Lim, Noha N; Froguel, Philippe P; Waterworth, Dawn M DM; Vollenweider, Peter P; Waeber, Gerard G; Jarvelin, Marjo-Riitta MR; Mooser, Vincent V; Scott, James J; Hall, Alistair S AS; Schunkert, Heribert H; Anand, Sonia S SS; Collins, Rory R; Samani, Nilesh J NJ; Watkins, Hugh H; Kooner, Jaspal S JS
Inflammation and stress-related candidate genes, plasma interleukin-6 levels, and longevity in older adults.
Experimental Gerontology
Walston, Jeremy D JD; Matteini, Amy M AM; Nievergelt, Caroline C; Lange, Leslie A LA; Fallin, Dani M DM; Barzilai, Nir N; Ziv, Elad E; Pawlikowska, Ludmila L; Kwok, Pui P; Cummings, Steve R SR; Kooperberg, Charles C; LaCroix, Andrea A; Tracy, Russell P RP; Atzmon, Gil G; Lange, Ethan M EM; Reiner, Alex P AP
Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.
Plos Genetics
Lowe, Jennifer K JK; Maller, Julian B JB; Pe'er, Itsik I; Neale, Benjamin M BM; Salit, Jacqueline J; Kenny, Eimear E EE; Shea, Jessica L JL; Burkhardt, Ralph R; Smith, J Gustav JG; Ji, Weizhen W; Noel, Martha M; Foo, Jia Nee JN; Blundell, Maude L ML; Skilling, Vita V; Garcia, Laura L; Sullivan, Marcia L ML; Lee, Heather E HE; Labek, Anna A; Ferdowsian, Hope H; Auerbach, Steven B SB; Lifton, Richard P RP; Newton-Cheh, Christopher C; Breslow, Jan L JL; Stoffel, Markus M; Daly, Mark J MJ; Altshuler, David M DM; Friedman, Jeffrey M JM
A common variant of the interleukin 6 receptor (IL-6r) gene increases IL-6r and IL-6 levels, without other inflammatory effects.
Genes And Immunity
Rafiq, S S; Frayling, T M TM; Murray, A A; Hurst, A A; Stevens, K K; Weedon, M N MN; Henley, W W; Ferrucci, L L; Bandinelli, S S; Corsi, A-M AM; Guralnik, J M JM; Melzer, D D