Blunted diurnal interleukin-6 rhythm is associated with amygdala emotional hyporeactivity and depression: a modulating role of gene-stressor interactions.
Association of Polymorphisms of IL-6 Pathway Genes (IL6, IL6R and IL6ST) with COVID-19 Severity in an Amazonian Population.
Viruses
Rodrigues, Fabíola Brasil Barbosa FBB; da Silva, Rosilene R; Santos, Erika Ferreira Dos EFD; de Brito, Mioni Thieli Figueiredo Magalhães MTFM; da Silva, Andréa Luciana Soares ALS; de Meira Leite, Mauro M; Póvoa da Costa, Flávia F; de Nazaré do Socorro de Almeida Viana, Maria M; de Sarges, Kevin Matheus Lima KML; Cantanhede, Marcos Henrique Damasceno MHD; Veríssimo, Adriana de Oliveira Lameira AOL; Carvalho, Mayara da Silva MDS; Henriques, Daniele Freitas DF; Silva, Carla Pinheiro da CPD; Costa, Igor Brasil IB; Nunes, Juliana Abreu Lima JAL; Costa, Iran Barros IB; Viana, Giselle Maria Rachid GMR; Queiroz, Maria Alice Freitas MAF; Lima, Sandra Souza SS; Lopes, Jeferson da Costa JDC; Torres, Maria Karoliny da Silva MKDS; Vallinoto, Izaura Maria Vieira Cayres IMVC; Bichara, Carlos David Araújo CDA; Vallinoto, Antonio Carlos Rosário ACR; Santos, Eduardo José Melo Dos EJMD
Advanced statistics identification of participant and treatment predictors associated with severe adverse effects induced by fluoropyrimidine-based chemotherapy.
Cancer Chemotherapy And Pharmacology
Korver, Samantha K SK; Bowen, Joanne M JM; Gibson, Rachel J RJ; Ball, Imogen A IA; Secombe, Kate R KR; Wain, Taylor J TJ; Logan, Richard M RM; Tuke, Jonathan J; Mead, Kelly R KR; Richards, Alison M AM; Karapetis, Christos S CS; Keefe, Dorothy M DM; Coller, Janet K JK
Thrombophilia and Immune-Related Genetic Markers in Long COVID.
Viruses
da Silva, Rosilene R; de Sarges, Kevin Matheus Lima KML; Cantanhede, Marcos Henrique Damasceno MHD; da Costa, Flávia Póvoa FP; Dos Santos, Erika Ferreira EF; Rodrigues, Fabíola Brasil Barbosa FBB; de Nazaré do Socorro de Almeida Viana, Maria M; de Meira Leite, Mauro M; da Silva, Andréa Luciana Soares ALS; de Brito, Mioni Thieli Magalhães MTM; da Silva Torres, Maria Karoliny MK; Queiroz, Maria Alice Freitas MAF; Vallinoto, Izaura Maria Vieira Cayres IMVC; Henriques, Daniele Freitas DF; Dos Santos, Carla Pinheiro CP; Viana, Giselle Maria Rachid GMR; Quaresma, Juarez Antônio Simões JAS; Falcão, Luiz Fábio Magno LFM; Vallinoto, Antonio Carlos Rosário ACR; Dos Santos, Eduardo José Melo EJM
Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.
Nature Communications
Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA
Network expansion of genetic associations defines a pleiotropy map of human cell biology.
Nature Genetics
Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P
Publication Date: 2023-02-23
Variant appearance in text: IL6R: 1073A>C; Asp358Ala
Altered IL-6 signalling and risk of tuberculosis disease: a meta-analysis and Mendelian randomisation study.
Medrxiv : The Preprint Server For Health Sciences
Hamilton, Fergus F; Schurz, Haiko H; Yates, Tom A TA; Gilchrist, James J JJ; Möller, Marlo M; Naranbhai, Vivek V; Ghazal, Peter P; Timpson, Nicholas J NJ; , ; Parks, Tom T; Pollara, Gabriele G
Publication Date: 2023-02-08
Variant appearance in text: IL6R: Asp358Ala; rs2228145
Genotype-protein phenotype characterization of NOD2 and IL23R missense variants associated with inflammatory bowel disease: A paradigm from molecular modelling, dynamics, and docking simulations.
Clinical Value of IL6R Gene Variants as Predictive Biomarkers for Toxicity to Tocilizumab in Patients with Rheumatoid Arthritis.
Journal Of Personalized Medicine
Sainz, Luis L; Riera, Pau P; Moya, Patricia P; Bernal, Sara S; Casademont, Jordi J; Díaz-Torné, Cesar C; Millán, Ana Milena AM; Park, Hye Sang HS; Lasa, Adriana A; Corominas, Héctor H
Genetic studies of plasma analytes identify novel potential biomarkers for several complex traits.
Scientific Reports
Deming, Yuetiva Y; Xia, Jian J; Cai, Yefei Y; Lord, Jenny J; Del-Aguila, Jorge L JL; Fernandez, Maria Victoria MV; Carrell, David D; Black, Kathleen K; Budde, John J; Ma, ShengMei S; Saef, Benjamin B; Howells, Bill B; Bertelsen, Sarah S; Bailey, Matthew M; Ridge, Perry G PG; , ; Holtzman, David D; Morris, John C JC; Bales, Kelly K; Pickering, Eve H EH; Lee, Jin-Moo JM; Heitsch, Laura L; Kauwe, John J; Goate, Alison A; Piccio, Laura L; Cruchaga, Carlos C
Common and rare variant associations with clonal haematopoiesis phenotypes.
Nature
Kessler, Michael D MD; Damask, Amy A; O'Keeffe, Sean S; Banerjee, Nilanjana N; Li, Dadong D; Watanabe, Kyoko K; Marketta, Anthony A; Van Meter, Michael M; Semrau, Stefan S; Horowitz, Julie J; Tang, Jing J; Kosmicki, Jack A JA; Rajagopal, Veera M VM; Zou, Yuxin Y; Houvras, Yariv Y; Ghosh, Arkopravo A; Gillies, Christopher C; Mbatchou, Joelle J; White, Ryan R RR; Verweij, Niek N; Bovijn, Jonas J; Parikshak, Neelroop N NN; LeBlanc, Michelle G MG; Jones, Marcus M; , ; , ; Glass, David J DJ; Lotta, Luca A LA; Cantor, Michael N MN; Atwal, Gurinder S GS; Locke, Adam E AE; Ferreira, Manuel A R MAR; Deering, Raquel R; Paulding, Charles C; Shuldiner, Alan R AR; Thurston, Gavin G; Ferrando, Adolfo A AA; Salerno, Will W; Reid, Jeffrey G JG; Overton, John D JD; Marchini, Jonathan J; Kang, Hyun M HM; Baras, Aris A; Abecasis, Gonçalo R GR; Jorgenson, Eric E
Next-generation whole exome sequencing to delineate the genetic basis of primary congenital glaucoma.
Scientific Reports
Rauf, Bushra B; Khan, Shahid Y SY; Jiao, Xiaodong X; Irum, Bushra B; Ashfaq, Ramla R; Zehra, Mubashra M; Khan, Asma A AA; Naeem, Muhammad Asif MA; Shahzad, Mohsin M; Riazuddin, Sheikh S; Hejtmancik, J Fielding JF; Riazuddin, S Amer SA
Outcomes of Genetic Testing-Based Cardiac Rehabilitation Program in Patients with Acute Myocardial Infarction after Percutaneous Coronary Intervention.
Association of TGFB1 rs1800469 and BCMO1 rs6564851 with coronary heart disease and IL1B rs16944 with all-cause mortality in men from the Northern Ireland PRIME study.
Plos One
Mooney, Rachel E RE; Linden, Gerry J GJ; Winning, Lewis L; Linden, Katie K; Kee, Frank F; McKeown, Pascal P PP; Woodside, Jayne V JV; Patterson, Christopher C CC; McKay, Gareth J GJ
Genetic LGALS1 Variants Are Associated with Heterogeneity in Galectin-1 Serum Levels in Patients with Early Arthritis.
International Journal Of Molecular Sciences
Triguero-Martínez, Ana A; Roy-Vallejo, Emilia E; Montes, Nuria N; de la Fuente, Hortensia H; Ortiz, Ana María AM; Castañeda, Santos S; González-Álvaro, Isidoro I; Lamana, Amalia A
Genome-wide meta-analysis of iron status biomarkers and the effect of iron on all-cause mortality in HUNT.
Communications Biology
Moksnes, Marta R MR; Graham, Sarah E SE; Wu, Kuan-Han KH; Hansen, Ailin Falkmo AF; Gagliano Taliun, Sarah A SA; Zhou, Wei W; Thorstensen, Ketil K; Fritsche, Lars G LG; Gill, Dipender D; Mason, Amy A; Cucca, Francesco F; Schlessinger, David D; Abecasis, Gonçalo R GR; Burgess, Stephen S; Åsvold, Bjørn Olav BO; Nielsen, Jonas B JB; Hveem, Kristian K; Willer, Cristen J CJ; Brumpton, Ben M BM
Outcome predictors in SARS-CoV-2 disease (COVID-19): The prominent role of IL-6 levels and an IL-6 gene polymorphism in a western Sicilian population.
The Journal Of Infection
Giannitrapani, Lydia L; Augello, Giuseppa G; Mirarchi, Luigi L; Amodeo, Simona S; Veronese, Nicola N; Sasso, Bruna Lo BL; Giglio, Rosaria Vincenza RV; Licata, Anna A; Barbagallo, Mario M; Ciaccio, Marcello M; Cervello, Melchiorre M; Soresi, Maurizio M
Genetic and Clinical Factors Associated with Olokizumab Treatment in Russian Patients with Rheumatoid Arthritis.
Journal Of Personalized Medicine
Mikhaylenko, Dmitry S DS; Kuznetsova, Ekaterina B EB; Musatova, Viktoria V VV; Bure, Irina V IV; Deryagina, Tatiana A TA; Alekseeva, Ekaterina A EA; Tarasov, Vadim V VV; Zamyatnin, Andrey A AA; Nemtsova, Marina V MV
Genome-wide pleiotropy analysis of coronary artery disease and pneumonia identifies shared immune pathways.
Science Advances
Yu, Zhi Z; Zekavat, Seyedeh M SM; Haidermota, Sara S; Bernardo, Rachel R; MacDonald, Bryan T BT; Libby, Peter P; Finucane, Hilary K HK; Natarajan, Pradeep P
Publication Date: 2022-04-22
Variant appearance in text: IL6R: Asp358Ala; rs2228145
Associations of Immune Genetic Variability with Gulf War Illness in 1990-1991 Gulf War Veterans from the Gulf War Illness Consortium (GWIC) Multisite Case-Control Study.
Brain Sciences
Coller, Janet K JK; Tuke, Jonathan J; Wain, Taylor J TJ; Quinn, Emily E; Steele, Lea L; Abreu, Maria M; Aenlle, Kristina K; Klimas, Nancy N; Sullivan, Kimberly K
Association between Biomarkers of Oxidative Stress and Inflammation with Cardiac Necrosis and Heart Failure in Non-ST Segment Elevation Myocardial Infarction Patients and Various Degrees of Kidney Function.
Oxidative Medicine And Cellular Longevity
Roumeliotis, Stefanos S; Veljkovic, Andrej A; Georgianos, Panagiotis I PI; Lazarevic, Gordana G; Perisic, Zoran Z; Hadzi-Djokic, Jovan J; Liakopoulos, Vassilios V; Kocic, Gordana G
IL-6 receptor blockade does not slow β cell loss in new-onset type 1 diabetes.
Jci Insight
Greenbaum, Carla J CJ; Serti, Elisavet E; Lambert, Katharina K; Weiner, Lia J LJ; Kanaparthi, Sai S; Lord, Sandra S; Gitelman, Stephen E SE; Wilson, Darrell M DM; Gaglia, Jason L JL; Griffin, Kurt J KJ; Russell, William E WE; Raskin, Philip P; Moran, Antoinette A; Willi, Steven M SM; Tsalikian, Eva E; DiMeglio, Linda A LA; Herold, Kevan C KC; Moore, Wayne V WV; Goland, Robin R; Harris, Mark M; Craig, Maria E ME; Schatz, Desmond A DA; Baidal, David A DA; Rodriguez, Henry H; Utzschneider, Kristina M KM; Nel, Hendrik J HJ; Soppe, Carol L CL; Boyle, Karen D KD; Cerosaletti, Karen K; Keyes-Elstein, Lynette L; Long, S Alice SA; Thomas, Ranjeny R; McNamara, James G JG; Buckner, Jane H JH; Sanda, Srinath S; ,